LOCUS       NC_016845.1            22166 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_016845.1 Klebsiella pneumoniae subsp. pneumoniae HS11286
            chromosome, complete genome.
ACCESSION   NC_016845
VERSION     NC_016845.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:53:27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2761811
            Orig. end    :: 2783977
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22166
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2771811:2773977]"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12166
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     cand_cluster    1..22166
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22166
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="4"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     CDS             433..1905
                     /NRPS_PKS="Domain: Beta_elim_lyase (181-397). E-value:
                     1.2e-12. Score: 39.5. Matches aSDomain:
                     nrpspksdomains_ctg1_2623_Beta_elim_lyase.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 425.7;
                     E-value: 3.4e-129)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2623"
                     /transl_table=11
                     /translation="MSTLNPILAGSAQSVEAYQQVIEQTSQAVVQWLKQPEMYQGKSVD
                     ELRERISLEFNEQGLGNQAAIDRAIEYFLKDSLSVHHPQCVAHLHCPSLVISQAAEVLI
                     NATNQSMDSWDQSPSATIIEMKLIEWLRARVGFPAGDAGVFTSGGTQSNLMGLMLARDA
                     FFARQGHSIQQDGLPGDIRKYKVLCSENAHFSVQKNMALMGLGYRSVTLVKTDEFARMD
                     VSDLQAKIAQAQANGEQIMAIVATAGTTDAGAIDPLRDIAGIAAEHQIWLHVDAAWGGA
                     LLLSEQYRDYLDGLELVDSVTLDFHKQFFQTISCGAFLLKDARHYELMRYQAAYLNSEF
                     DEEHGVPNLVSKSLQTTRRFDALKLWMGLEALGQKQYAAIIDHGVTMAKNVAEYVKSQP
                     TLELVMQPQLASVLFRSRPAQMAGSDAAAIALLNQRVGDALLASGRANVGVTEHNGVTC
                     LKLTLLNPVVTLDDVKVLLNLVERTAQELLAQ"
     PFAM_domain     625..1680
                     /aSDomain="Pyridoxal_deC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00282.21"
                     /description="Pyridoxal-dependent decarboxylase conserved
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2623_0098"
                     /evalue="1.20E-64"
                     /label="ctg1_2623"
                     /locus_tag="ctg1_2623"
                     /protein_end="416"
                     /protein_start="64"
                     /score="218.5"
                     /tool="antismash"
                     /translation="AIDRAIEYFLKDSLSVHHPQCVAHLHCPSLVISQAAEVLINATNQ
                     SMDSWDQSPSATIIEMKLIEWLRARVGFPAGDAGVFTSGGTQSNLMGLMLARDAFFARQ
                     GHSIQQDGLPGDIRKYKVLCSENAHFSVQKNMALMGLGYRSVTLVKTDEFARMDVSDLQ
                     AKIAQAQANGEQIMAIVATAGTTDAGAIDPLRDIAGIAAEHQIWLHVDAAWGGALLLSE
                     QYRDYLDGLELVDSVTLDFHKQFFQTISCGAFLLKDARHYELMRYQAAYLNSEFDEEHG
                     VPNLVSKSLQTTRRFDALKLWMGLEALGQKQYAAIIDHGVTMAKNVAEYVKSQPTLELV
                     MQPQLASVLFRS"
     aSDomain        976..1623
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2623_Beta_elim_lyase.1"
                     /evalue="1.20E-12"
                     /label="ctg1_2623_Beta_elim_lyase.1"
                     /locus_tag="ctg1_2623"
                     /protein_end="397"
                     /protein_start="181"
                     /score="39.5"
                     /tool="antismash"
                     /translation="RKYKVLCSENAHFSVQKNMALMGLGYRSVTLVKTDEFARMDVSDL
                     QAKIAQAQANGEQIMAIVATAGTTDAGAIDPLRDIAGIAAEHQIWLHVDAAWGGALLLS
                     EQYRDYLDGLELVDSVTLDFHKQFFQTISCGAFLLKDARHYELMRYQAAYLNSEFDEEH
                     GVPNLVSKSLQTTRRFDALKLWMGLEALGQKQYAAIIDHGVTMAKNVAEYVKS"
     CDS             2112..2993
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 137.5; E-value: 9.1e-42)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2624"
                     /transl_table=11
                     /translation="MEKRLPGLDLDALRSFVTGMECGSFAQAALRLSRSTSAVSAQLKK
                     LESQCGAALVTKQGRHLVLTAEGEKLMSYARRLLALNDETLRALQGERLTGEIHLGMQE
                     DFGESLMPEILGQFKRHHPQVRIVARVDRNGPLRQALAEEALDLALLWQTEDQGSGLGL
                     CPLAWIAHPDLDIRALLVSGEPLPLVMFDSPCLMRSRAIACLDAAGIPWQVVFVSHSLS
                     GIWAAVQAGLGLTIRTRIGMPGNLRPAGGLLPAPGSLAVSLRQTPREEHHSAAVALLGE
                     LMTEALQGWLNR"
     PFAM_domain     2139..2318
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2624_0099"
                     /evalue="5.00E-16"
                     /label="ctg1_2624"
                     /locus_tag="ctg1_2624"
                     /protein_end="69"
                     /protein_start="9"
                     /score="58.5"
                     /tool="antismash"
                     /translation="LDALRSFVTGMECGSFAQAALRLSRSTSAVSAQLKKLESQCGAAL
                     VTKQGRHLVLTAEGE"
     PFAM_domain     2385..2972
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2624_0100"
                     /evalue="3.20E-20"
                     /label="ctg1_2624"
                     /locus_tag="ctg1_2624"
                     /protein_end="287"
                     /protein_start="91"
                     /score="72.5"
                     /tool="antismash"
                     /translation="ERLTGEIHLGMQEDFGESLMPEILGQFKRHHPQVRIVARVDRNGP
                     LRQALAEEALDLALLWQTEDQGSGLGLCPLAWIAHPDLDIRALLVSGEPLPLVMFDSPC
                     LMRSRAIACLDAAGIPWQVVFVSHSLSGIWAAVQAGLGLTIRTRIGMPGNLRPAGGLLP
                     APGSLAVSLRQTPREEHHSAAVALLGELMTEAL"
     CDS             complement(3103..4293)
                     /gene_functions="other (smcogs) SMCOG1241:lipoprotein dsbF
                     (Score: 118; E-value: 6e-36)"
                     /gene_kind="other"
                     /locus_tag="ctg1_2625"
                     /transl_table=11
                     /translation="MSILIAFLGGMLTLLSPCTLPVIPLLFASVRGRRGQLAIMLAGMA
                     LMFGAVSWLVTVASGWVVNLTLAGRGLALAFFALVGLSLLSQRVAQRLTSPLVALGNQL
                     NDASSRQRGWIGSLLAGLAVGLLWAPCAGPVLGAILSLGFVHPGQATTGGLLLAYGSGG
                     ALMLFLLGWCGAALIARLRRGQAFGERLRRLAGGAMLASVALIASGGDRYLQSAGGLSQ
                     ALEQRLAARLPQPEQKTSLQPIAAPQPSSAMPSLAGGSAWINSPALTPERLKGKVVLVD
                     FWTRECINCQHTLPYVRDWANKYRAAGLVVIGVHTPEYPWERSLPLLRQAVKDWRITYP
                     VVADNEYAIWNAFGNQYWPAHYIFDARGQLRYTAFGEGDYARQEQVIQQLLQESKA"
     PFAM_domain     complement(3178..3480)
                     /aSDomain="AhpC-TSA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00578.23"
                     /description="AhpC/TSA family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2625_0102"
                     /evalue="8.80E-11"
                     /label="ctg1_2625"
                     /locus_tag="ctg1_2625"
                     /protein_end="372"
                     /protein_start="271"
                     /score="41.9"
                     /tool="antismash"
                     /translation="RLKGKVVLVDFWTRECINCQHTLPYVRDWANKYRAAGLVVIGVHT
                     PEYPWERSLPLLRQAVKDWRITYPVVADNEYAIWNAFGNQYWPAHYIFDARGQLRY"
     PFAM_domain     complement(3694..4278)
                     /aSDomain="DsbD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02683.17"
                     /description="Cytochrome C biogenesis protein transmembrane
                     region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2625_0101"
                     /evalue="4.30E-12"
                     /label="ctg1_2625"
                     /locus_tag="ctg1_2625"
                     /protein_end="200"
                     /protein_start="5"
                     /score="46.5"
                     /tool="antismash"
                     /translation="AFLGGMLTLLSPCTLPVIPLLFASVRGRRGQLAIMLAGMALMFGA
                     VSWLVTVASGWVVNLTLAGRGLALAFFALVGLSLLSQRVAQRLTSPLVALGNQLNDASS
                     RQRGWIGSLLAGLAVGLLWAPCAGPVLGAILSLGFVHPGQATTGGLLLAYGSGGALMLF
                     LLGWCGAALIARLRRGQAFGERLRRLAGGAML"
     CDS             complement(4396..5739)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 155.4; E-value: 5e-47)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2626"
                     /transl_table=11
                     /translation="MRFWPASLQSRLMALLFLALLLANTLTLSLLFYERMSSARSVMLG
                     NLASDVATSVAILDRLPAAERPQWLPKLARGNYRYLLDAGERGDYPDNWRARDAARSLQ
                     EALSAQYPVSIVAIPGPRQHIQAHITLHDGAPLTLDLWPKLPAIARWLPVVLIAQFVLL
                     LACAWYAVRQVLLPISRFTHAVNALEPASDTAGTMAEQGPEEVRRAARAFNAMQARIHD
                     HLQERARILAAISHDLQTPITRMKLRVEMADQPELRDKLLQDLDNMTRLVREGIAFART
                     SQPLEEARQRLNLDAFLDTIVCDYADVGRPVQFCPEETAGVVWIPPQALRRVMTNLIDN
                     ALKFGTTATVTLTRDAVGDITLHVLDEGPGIPEAALQAVLQPFYRLEDSRNRDTGGTGL
                     GLAIAAQLVSQMDGALRLANRPQGGLDASVRLAAAGLYPDVSSGKTDN"
     PFAM_domain     complement(4447..4758)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2626_0103"
                     /evalue="5.50E-20"
                     /label="ctg1_2626"
                     /locus_tag="ctg1_2626"
                     /protein_end="431"
                     /protein_start="327"
                     /score="72.0"
                     /tool="antismash"
                     /translation="QALRRVMTNLIDNALKFGTTATVTLTRDAVGDITLHVLDEGPGIP
                     EAALQAVLQPFYRLEDSRNRDTGGTGLGLAIAAQLVSQMDGALRLANRPQGGLDASVRL
                     "
     CDS             complement(5736..6476)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 203.4; E-value: 5.8e-62)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2627"
                     /transl_table=11
                     /translation="LERIDHILVVDDDRDIRELIVDYLEKSGYRASGAANGKAMWSVLK
                     NHQIDLIVLDIMMPGEDGLTLCRQLRANPQQDIPVLMLTARTDDSDRILGLEMGADDYL
                     IKPFVARELLARIKAILRRTRALPPNLQITEAGRLIAFGDWLLDTAARHLLDDSGAIVA
                     LSGAEYRLLRVFLDHPQRVLNRDQLLNLTQGRDAELFERSIDLLVSRLRQRLREDAREP
                     AYIKTVRSEGYMLSVPVSIRERHE"
     PFAM_domain     complement(5772..5993)
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2627_0105"
                     /evalue="2.30E-19"
                     /label="ctg1_2627"
                     /locus_tag="ctg1_2627"
                     /protein_end="235"
                     /protein_start="161"
                     /score="69.4"
                     /tool="antismash"
                     /translation="VALSGAEYRLLRVFLDHPQRVLNRDQLLNLTQGRDAELFERSIDL
                     LVSRLRQRLREDAREPAYIKTVRSEGYML"
     PFAM_domain     complement(6123..6458)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2627_0104"
                     /evalue="2.70E-32"
                     /label="ctg1_2627"
                     /locus_tag="ctg1_2627"
                     /protein_end="118"
                     /protein_start="6"
                     /score="111.4"
                     /tool="antismash"
                     /translation="ILVVDDDRDIRELIVDYLEKSGYRASGAANGKAMWSVLKNHQIDL
                     IVLDIMMPGEDGLTLCRQLRANPQQDIPVLMLTARTDDSDRILGLEMGADDYLIKPFVA
                     RELLARIK"
     CDS             complement(6563..7555)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 135;
                     E-value: 6.8e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2628"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.4e-13, bitscore:
                     49.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.6e-18, bitscore: 65.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRLSLIRYTSAVALGLSTLWSAAVCAAEDAGAFDKIQQIRAGDL
                     NIGYVDIGPRDGQPVILLHGWPYDIQSYAQVAPALAQKGYRVIVPYLRGYGTTRFLSAS
                     TPRNGQPSAMAADIVHLMDALNIRQADLAGFDWGARTADIVAALWPQRVKSLVSVSGYL
                     ISSQQIGEKPLPPQAELSWWYQFYFATPRGEAGYRQNTHDFAKFIWHQASPQWQFSDAT
                     FAKTARALDNPDHVAITISNYRWRLGLEKGEAKYAGYEQRLAALPPITVPTITLEGANN
                     GAPHPAPASYRAKFTGKYEHRDLPGAVGHNPPQEDPTAFVQAVVDADRL"
     PFAM_domain     complement(6998..7381)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00561.22"
                     /description="alpha/beta hydrolase fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2628_0106"
                     /evalue="6.60E-18"
                     /label="ctg1_2628"
                     /locus_tag="ctg1_2628"
                     /protein_end="186"
                     /protein_start="58"
                     /score="65.4"
                     /tool="antismash"
                     /translation="PVILLHGWPYDIQSYAQVAPALAQKGYRVIVPYLRGYGTTRFLSA
                     STPRNGQPSAMAADIVHLMDALNIRQADLAGFDWGARTADIVAALWPQRVKSLVSVSGY
                     LISSQQIGEKPLPPQAELSWWYQF"
     CDS             7799..8818
                     /locus_tag="ctg1_2629"
                     /transl_table=11
                     /translation="MAIFDGHNDLLLNLWLHHREDPVSAFFAGIENGHLDYPRMLQGGF
                     AGGLFALFVPPQEYIARMTPQYASQRWDPIDILWQQLAILKQLIAHSAGRLRLCLSAAD
                     IERCREDKVLAMVAHIEGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNGSFP
                     GSPDTGPGLTAAGIDLIKQVNALKMQIDVSHMNEKAFWDTAHHATSPLVATHSNAHALC
                     PQPRNLTDQQLRAIRDSGGVVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGED
                     HVALGSDFDGITLPDELGDVAGLPRLINTLRASGYDQLVLDKLLWRNWLRVLKNVWQQ"
     PFAM_domain     7802..8800
                     /aSDomain="Peptidase_M19"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01244.23"
                     /description="Membrane dipeptidase (Peptidase family M19)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2629_0107"
                     /evalue="3.00E-91"
                     /label="ctg1_2629"
                     /locus_tag="ctg1_2629"
                     /protein_end="334"
                     /protein_start="1"
                     /score="306.0"
                     /tool="antismash"
                     /translation="AIFDGHNDLLLNLWLHHREDPVSAFFAGIENGHLDYPRMLQGGFA
                     GGLFALFVPPQEYIARMTPQYASQRWDPIDILWQQLAILKQLIAHSAGRLRLCLSAADI
                     ERCREDKVLAMVAHIEGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNGSFPG
                     SPDTGPGLTAAGIDLIKQVNALKMQIDVSHMNEKAFWDTAHHATSPLVATHSNAHALCP
                     QPRNLTDQQLRAIRDSGGVVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGEDH
                     VALGSDFDGITLPDELGDVAGLPRLINTLRASGYDQLVLDKLLWRNWLRVLK"
     CDS             9081..10007
                     /locus_tag="ctg1_2630"
                     /transl_table=11
                     /translation="MFIKVLGSAAGGGFPQWNCNCANCQGLRDGTIQAAPRTQSSIIVS
                     DNGKEWVLCNASPDISQQIANTPELNKAGVLRGTHIGGIILTDSQIDHTTGLLSLREGC
                     PHQVWCTPEVHEDLSTGFPVFTMLRHWNGGLVHHPIAPQQPFTVDACPDLQFTAVPIAS
                     NAPPYSPYRDRPLPGHNVALFIENRRNGQTLFYAPGLGEPDETLLPWLQKADCLLIDGT
                     VWQDDELQAAGVGRNTGRDMGHLALGDEHGMMALLASLPAKRKILIHINNTNPILNEQS
                     PQRQALTQQGIEVSWDGMAITLQDTAC"
     aSDomain        9087..9989
                     /aSDomain="TIGR02108"
                     /aSTool="tigrfam"
                     /description="PQQ_syn_pqqB: coenzyme PQQ biosynthesis
                     protein B"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2630_0026"
                     /evalue="1.40E-124"
                     /identifier="TIGR02108"
                     /label="ctg1_2630"
                     /locus_tag="ctg1_2630"
                     /protein_end="303"
                     /protein_start="2"
                     /score="413.1"
                     /tool="antismash"
                     /translation="IKVLGSAAGGGFPQWNCNCANCQGLRDGTIQAAPRTQSSIIVSDN
                     GKEWVLCNASPDISQQIANTPELNKAGVLRGTHIGGIILTDSQIDHTTGLLSLREGCPH
                     QVWCTPEVHEDLSTGFPVFTMLRHWNGGLVHHPIAPQQPFTVDACPDLQFTAVPIASNA
                     PPYSPYRDRPLPGHNVALFIENRRNGQTLFYAPGLGEPDETLLPWLQKADCLLIDGTVW
                     QDDELQAAGVGRNTGRDMGHLALGDEHGMMALLASLPAKRKILIHINNTNPILNEQSPQ
                     RQALTQQGIEVSWDGMAITL"
     PFAM_domain     9231..9890
                     /aSDomain="Lactamase_B_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12706.9"
                     /description="Beta-lactamase superfamily domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2630_0108"
                     /evalue="1.50E-44"
                     /label="ctg1_2630"
                     /locus_tag="ctg1_2630"
                     /protein_end="270"
                     /protein_start="50"
                     /score="152.0"
                     /tool="antismash"
                     /translation="WVLCNASPDISQQIANTPELNKAGVLRGTHIGGIILTDSQIDHTT
                     GLLSLREGCPHQVWCTPEVHEDLSTGFPVFTMLRHWNGGLVHHPIAPQQPFTVDACPDL
                     QFTAVPIASNAPPYSPYRDRPLPGHNVALFIENRRNGQTLFYAPGLGEPDETLLPWLQK
                     ADCLLIDGTVWQDDELQAAGVGRNTGRDMGHLALGDEHGMMALLASLPAKRKILIHI"
     CDS             10001..10756
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2631"
                     /sec_met_domain="TIGR02111 (E-value: 2.6e-117, bitscore:
                     388.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLITDTLSPQAFEEALRAKGAFYHIHHPYHIAMHNGDATREQIQG
                     WVANRFYYQTTIPLKDAAIMANCPDAQTRRKWVQRILDHDGSHGEDGGIEAWLRLGEAV
                     GLSRDDLLSERHVLPGVRFAVDAYLNFARRACWQEAACSSLTELFAPQIHQSRLDSWPQ
                     HYPWIKEEGYFYFRSRLSQANRDVEHGLALAKAYCDSAEKQNRMLEILQFKLDILWSML
                     DAMTMAYALQRPPYHTVTDKAAWHTTRLV"
     aSDomain        10019..10723
                     /aSDomain="TIGR02111"
                     /aSTool="tigrfam"
                     /description="PQQ_syn_pqqC: coenzyme PQQ biosynthesis
                     protein C"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2631_0027"
                     /evalue="2.30E-117"
                     /identifier="TIGR02111"
                     /label="ctg1_2631"
                     /locus_tag="ctg1_2631"
                     /protein_end="241"
                     /protein_start="6"
                     /score="388.6"
                     /tool="antismash"
                     /translation="LSPQAFEEALRAKGAFYHIHHPYHIAMHNGDATREQIQGWVANRF
                     YYQTTIPLKDAAIMANCPDAQTRRKWVQRILDHDGSHGEDGGIEAWLRLGEAVGLSRDD
                     LLSERHVLPGVRFAVDAYLNFARRACWQEAACSSLTELFAPQIHQSRLDSWPQHYPWIK
                     EEGYFYFRSRLSQANRDVEHGLALAKAYCDSAEKQNRMLEILQFKLDILWSMLDAMTMA
                     YALQRPPYHTVTD"
     PFAM_domain     10040..10669
                     /aSDomain="TENA_THI-4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03070.18"
                     /description="TENA/THI-4/PQQC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2631_0109"
                     /evalue="9.40E-69"
                     /label="ctg1_2631"
                     /locus_tag="ctg1_2631"
                     /protein_end="223"
                     /protein_start="13"
                     /score="231.5"
                     /tool="antismash"
                     /translation="EALRAKGAFYHIHHPYHIAMHNGDATREQIQGWVANRFYYQTTIP
                     LKDAAIMANCPDAQTRRKWVQRILDHDGSHGEDGGIEAWLRLGEAVGLSRDDLLSERHV
                     LPGVRFAVDAYLNFARRACWQEAACSSLTELFAPQIHQSRLDSWPQHYPWIKEEGYFYF
                     RSRLSQANRDVEHGLALAKAYCDSAEKQNRMLEILQFKLDILWSMLD"
     CDS             10759..11037
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2632"
                     /sec_met_domain="PF05402 (E-value: 3.3e-15, bitscore: 54.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.1e-38, bitscore:
                     128.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKTSIVAFRRGYRLQWEAAQESHVILYPEGMAKLNETAAAILEL
                     VDGRRDVAAIIAMLNERFPEAGGVDDDVIEFLQIACQQKWITCREPE"
     aSDomain        10780..11016
                     /aSDomain="TIGR03859"
                     /aSTool="tigrfam"
                     /description="PQQ_PqqD: coenzyme PQQ biosynthesis protein
                     PqqD"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2632_0028"
                     /evalue="9.90E-35"
                     /identifier="TIGR03859"
                     /label="ctg1_2632"
                     /locus_tag="ctg1_2632"
                     /protein_end="86"
                     /protein_start="7"
                     /score="116.3"
                     /tool="antismash"
                     /translation="AFRRGYRLQWEAAQESHVILYPEGMAKLNETAAAILELVDGRRDV
                     AAIIAMLNERFPEAGGVDDDVIEFLQIACQQKWI"
     PFAM_domain     10828..11016
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2632_0110"
                     /evalue="2.80E-14"
                     /label="ctg1_2632"
                     /locus_tag="ctg1_2632"
                     /protein_end="86"
                     /protein_start="23"
                     /score="53.2"
                     /tool="antismash"
                     /translation="HVILYPEGMAKLNETAAAILELVDGRRDVAAIIAMLNERFPEAGG
                     VDDDVIEFLQIACQQKWI"
     CDS             11024..12166
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2633"
                     /sec_met_domain="PF04055 (E-value: 1e-22, bitscore: 79.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.1e-06, bitscore: 26.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.8e-06, bitscore: 26.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSQSKPTVNPPLWLLAELTYRCPLQCPYCSNPLDFARQDKELTTE
                     QWIEVFRQARAMGSVQLGFSGGEPLTRKDLPELIRAARDLGFYTNLITSGIGLTESKLD
                     AFSEAGLDHIQISFQASDEVLNAALAGNKKAFQQKLTMAKAVKARDYPMVLNFVLHRHN
                     IDQLDKIIELCIELEADDVELATCQFYGWAFLNREGLLPTREQIARAEQVVADYRQKMA
                     ASGNLTNLLFVTPDYYEERPKGCMGGWGSIFLSVTPEGTALPCHSARQLPVAFPSVLEQ
                     SLESIWYDSFGFNRYRGYDWMPEPCRSCDEKEKDFGGCRCQAFMLTGSADNADPVCSKS
                     PHHHKILEARREAACSDIKVSQLQFRNRTRSQLIFQTRDL"
     aSDomain        11042..12124
                     /aSDomain="TIGR02109"
                     /aSTool="tigrfam"
                     /description="PQQ_syn_pqqE: coenzyme PQQ biosynthesis
                     enzyme PqqE"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2633_0029"
                     /evalue="1.00E-190"
                     /identifier="TIGR02109"
                     /label="ctg1_2633"
                     /locus_tag="ctg1_2633"
                     /protein_end="367"
                     /protein_start="6"
                     /score="631.2"
                     /tool="antismash"
                     /translation="TVNPPLWLLAELTYRCPLQCPYCSNPLDFARQDKELTTEQWIEVF
                     RQARAMGSVQLGFSGGEPLTRKDLPELIRAARDLGFYTNLITSGIGLTESKLDAFSEAG
                     LDHIQISFQASDEVLNAALAGNKKAFQQKLTMAKAVKARDYPMVLNFVLHRHNIDQLDK
                     IIELCIELEADDVELATCQFYGWAFLNREGLLPTREQIARAEQVVADYRQKMAASGNLT
                     NLLFVTPDYYEERPKGCMGGWGSIFLSVTPEGTALPCHSARQLPVAFPSVLEQSLESIW
                     YDSFGFNRYRGYDWMPEPCRSCDEKEKDFGGCRCQAFMLTGSADNADPVCSKSPHHHKI
                     LEARREAACSDIKVSQLQFRN"
     PFAM_domain     11075..11542
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2633_0111"
                     /evalue="5.20E-22"
                     /label="ctg1_2633"
                     /locus_tag="ctg1_2633"
                     /protein_end="173"
                     /protein_start="17"
                     /score="79.1"
                     /tool="antismash"
                     /translation="LTYRCPLQCPYCSNPLDFARQDKELTTEQWIEVFRQARAMGSVQL
                     GFSGGEPLTRKDLPELIRAARDLGFYTNLITSGIGLTESKLDAFSEAGLDHIQISFQAS
                     DEVLNAALAGNKKAFQQKLTMAKAVKARDYPMVLNFVLHRHNIDQLDKIIEL"
     PFAM_domain     11756..11953
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2633_0112"
                     /evalue="6.80E-06"
                     /label="ctg1_2633"
                     /locus_tag="ctg1_2633"
                     /protein_end="310"
                     /protein_start="244"
                     /score="26.6"
                     /tool="antismash"
                     /translation="CMGGWGSIFLSVTPEGTALPCHSARQLPVAFPSVLEQSLESIWYD
                     SFGFNRYRGYDWMPEPCRSCD"
     CDS             12166..12915
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2634"
                     /sec_met_domain="Peptidase_M16 (E-value: 6.3e-38, bitscore:
                     128.3, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLATRTVTLPGGLQATLVHQPQADRAAALARVAAGSHHEPSRFP
                     GLAHLLEHLLFYGGERYQDDDRLMGWVQRQGGSVNATTLARHSAFFFEVAADALADGVA
                     RLQEMLQAPLLLREDIQREVAVIDAEYRLIQQHEPSRREAAVRHAASAPAAFRRFQVGS
                     ADALAGDLAALQAALGDFHRTHYVARRMQLWLQGPQSLEALGELAARSPPGLPQARLRR
                     RRRRCAWASSLHCSWRSPASPRCGAAR"
     aSDomain        12181..12813
                     /aSDomain="TIGR02110"
                     /aSTool="tigrfam"
                     /description="PQQ_syn_pqqF: coenzyme PQQ biosynthesis
                     protein PqqF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2634_0030"
                     /evalue="8.70E-113"
                     /identifier="TIGR02110"
                     /label="ctg1_2634"
                     /locus_tag="ctg1_2634"
                     /protein_end="216"
                     /protein_start="5"
                     /score="376.3"
                     /tool="antismash"
                     /translation="RTVTLPGGLQATLVHQPQADRAAALARVAAGSHHEPSRFPGLAHL
                     LEHLLFYGGERYQDDDRLMGWVQRQGGSVNATTLARHSAFFFEVAADALADGVARLQEM
                     LQAPLLLREDIQREVAVIDAEYRLIQQHEPSRREAAVRHAASAPAAFRRFQVGSADALA
                     GDLAALQAALGDFHRTHYVARRMQLWLQGPQSLEALGELAARSPPGLP"
     PFAM_domain     12214..12624
                     /aSDomain="Peptidase_M16"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00675.22"
                     /description="Insulinase (Peptidase family M16)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2634_0113"
                     /evalue="1.10E-35"
                     /label="ctg1_2634"
                     /locus_tag="ctg1_2634"
                     /protein_end="153"
                     /protein_start="16"
                     /score="122.9"
                     /tool="antismash"
                     /translation="TLVHQPQADRAAALARVAAGSHHEPSRFPGLAHLLEHLLFYGGER
                     YQDDDRLMGWVQRQGGSVNATTLARHSAFFFEVAADALADGVARLQEMLQAPLLLREDI
                     QREVAVIDAEYRLIQQHEPSRREAAVRHAASAP"
     aSDomain        12981..14210
                     /aSDomain="TIGR02110"
                     /aSTool="tigrfam"
                     /description="PQQ_syn_pqqF: coenzyme PQQ biosynthesis
                     protein PqqF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2635_0031"
                     /evalue="3.80E-148"
                     /identifier="TIGR02110"
                     /label="ctg1_2635"
                     /locus_tag="ctg1_2635"
                     /protein_end="410"
                     /protein_start="0"
                     /score="493.2"
                     /tool="antismash"
                     /translation="MAGLRQRRLAGDVALNWLYQDRHLGWLALVFASDRPEEVDRQITH
                     WLQALQQTTPEQQLHYYQLSRRRFQALSPLDQLRQRAFGFAPGAPPAGFADFCAALQAA
                     PSVRLACQTVSPGEPVATQGFSLPLSRWRRRPESDPALAFAFYPQAAGDLVAKCPEEAA
                     PLLHLPSPGEPPRLLLRPPFYCSPDQAEGLARGEQLRPQLAALRHAGGHGEWHLFDGSW
                     QLTLQLPEPGRRPEAILQAILRQLALPVASLTPPPESIAIRYLMAQLPERLGTCGHQKG
                     WLAALAGGSAEDAQWIARQLSLITAPVNPPMPAPAPCRRGVERLVYPGGDTALLVFIPL
                     PDGASLAALRLLAQHCEPLFFQRLRVEQQIGYVVSCRYQRVADRDGLLMALQSPDRRAG
                     ELLRCGKDFLR"
     CDS             12981..14450
                     /locus_tag="ctg1_2635"
                     /transl_table=11
                     /translation="MAGLRQRRLAGDVALNWLYQDRHLGWLALVFASDRPEEVDRQITH
                     WLQALQQTTPEQQLHYYQLSRRRFQALSPLDQLRQRAFGFAPGAPPAGFADFCAALQAA
                     PSVRLACQTVSPGEPVATQGFSLPLSRWRRRPESDPALAFAFYPQAAGDLVAKCPEEAA
                     PLLHLPSPGEPPRLLLRPPFYCSPDQAEGLARGEQLRPQLAALRHAGGHGEWHLFDGSW
                     QLTLQLPEPGRRPEAILQAILRQLALPVASLTPPPESIAIRYLMAQLPERLGTCGHQKG
                     WLAALAGGSAEDAQWIARQLSLITAPVNPPMPAPAPCRRGVERLVYPGGDTALLVFIPL
                     PDGASLAALRLLAQHCEPLFFQRLRVEQQIGYVVSCRYQRVADRDGLLMALQSPDRRAG
                     ELLRCGKDFLRQLAPMDEATFRPLQQRLAAQIRASRPPEARALSALRQEYGLPELTPQA
                     VDALRVAEVADLAREMTRRRRRWQVLFTTGD"
     CDS             complement(14447..15184)
                     /locus_tag="ctg1_2636"
                     /transl_table=11
                     /translation="VTRNRLLLVQTGTPPTAIRQAHGDLPRWFRTLLAPWQTQLTTVRV
                     FEDEPLPTPDNQTLAVLTGSWAMVTDRLAWSERTADWIRQAVAIDMPLFGVCYGHQLMA
                     HALGGEVAYHPGGRESGSQTITLSPWGVDDPLLSGLPATFPAHLSHLQTVTRLPEGATV
                     LAASAHDPHQIVRYGPHAVSTQFHPEFTAPIARSLIRHREAVLQAEGIDAQRLHEEVQE
                     SPQGAAILTRFVSAFLTPDAPGH"
     PFAM_domain     complement(14609..14956)
                     /aSDomain="GATase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00117.30"
                     /description="Glutamine amidotransferase class-I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2636_0114"
                     /evalue="1.00E-17"
                     /label="ctg1_2636"
                     /locus_tag="ctg1_2636"
                     /protein_end="192"
                     /protein_start="76"
                     /score="64.6"
                     /tool="antismash"
                     /translation="ERTADWIRQAVAIDMPLFGVCYGHQLMAHALGGEVAYHPGGRESG
                     SQTITLSPWGVDDPLLSGLPATFPAHLSHLQTVTRLPEGATVLAASAHDPHQIVRYGPH
                     AVSTQFHPEFTA"
     CDS             complement(15297..17207)
                     /locus_tag="ctg1_2637"
                     /transl_table=11
                     /translation="MPLLRDEIRDHSAEEMLFIRRAAIAFLLVVVCFGVLIVNLYHLQV
                     EQHDFYQTRSNQNDIKMLPIAPSRGLIFDRNGIPLVQNITLYRLQVIPSKIHDMAALLQ
                     QLTPIVDLTPDDIASFRDDMHHTSRYKAVTLKSDLSDVEVARFAVNEFRFPGVTVESYQ
                     QREYPYGAELAHVVGYVSKINDSDLQRLAKNGEEENYAADRNIGKQGIEGYYEKALHGT
                     TGYQEVEVDNHGRVVRLLKEVPPVAGKNLYLTLDLHLQQYIESVLKGQRAAVVVVDPRD
                     GGVLAMVSSPSYDPNPFVKGIGYQAYKSLLENPDRPLINRVTQGLYPPASTVKPYMALS
                     ALSAGVITPNTTFFGAPTWTLPGTQRRYRDWLKTGHGMLNVTKAIEESADTFFYQVAFE
                     MGIDRIHEWLSKFGYGQSTGIDLNEEYAGVLPSREWKQRVHKKPWYQGDTISVGIGQGY
                     WIATPIQMVKALTTLLNNGKVQDPHLLYSMKQGNHVERYQQPANLPQVGDPKSPYWGIV
                     RNGMYGMANQPNGTGYKLFHTAPYQIAAKSGTSQVFSLKQNQTYNAKMIPVRLRDHIFY
                     TLFAPYQHPKVAMALILENGGGDGVVAGPTARAILDHIFVPQQASSAAADVPQRDSADA
                     Q"
     aSDomain        complement(15363..17150)
                     /aSDomain="TIGR03423"
                     /aSTool="tigrfam"
                     /description="pbp2_mrdA: penicillin-binding protein 2"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2637_0032"
                     /evalue="1.00E-227"
                     /identifier="TIGR03423"
                     /label="ctg1_2637"
                     /locus_tag="ctg1_2637"
                     /protein_end="615"
                     /protein_start="19"
                     /score="755.4"
                     /tool="antismash"
                     /translation="RRAAIAFLLVVVCFGVLIVNLYHLQVEQHDFYQTRSNQNDIKMLP
                     IAPSRGLIFDRNGIPLVQNITLYRLQVIPSKIHDMAALLQQLTPIVDLTPDDIASFRDD
                     MHHTSRYKAVTLKSDLSDVEVARFAVNEFRFPGVTVESYQQREYPYGAELAHVVGYVSK
                     INDSDLQRLAKNGEEENYAADRNIGKQGIEGYYEKALHGTTGYQEVEVDNHGRVVRLLK
                     EVPPVAGKNLYLTLDLHLQQYIESVLKGQRAAVVVVDPRDGGVLAMVSSPSYDPNPFVK
                     GIGYQAYKSLLENPDRPLINRVTQGLYPPASTVKPYMALSALSAGVITPNTTFFGAPTW
                     TLPGTQRRYRDWLKTGHGMLNVTKAIEESADTFFYQVAFEMGIDRIHEWLSKFGYGQST
                     GIDLNEEYAGVLPSREWKQRVHKKPWYQGDTISVGIGQGYWIATPIQMVKALTTLLNNG
                     KVQDPHLLYSMKQGNHVERYQQPANLPQVGDPKSPYWGIVRNGMYGMANQPNGTGYKLF
                     HTAPYQIAAKSGTSQVFSLKQNQTYNAKMIPVRLRDHIFYTLFAPYQHPKVAMALILEN
                     GGGDGVVAGPTARAILDHIF"
     PFAM_domain     complement(15372..16391)
                     /aSDomain="Transpeptidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00905.24"
                     /description="Penicillin binding protein transpeptidase
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2637_0116"
                     /evalue="6.10E-79"
                     /label="ctg1_2637"
                     /locus_tag="ctg1_2637"
                     /protein_end="612"
                     /protein_start="272"
                     /score="265.5"
                     /tool="antismash"
                     /translation="AVVVVDPRDGGVLAMVSSPSYDPNPFVKGIGYQAYKSLLENPDRP
                     LINRVTQGLYPPASTVKPYMALSALSAGVITPNTTFFGAPTWTLPGTQRRYRDWLKTGH
                     GMLNVTKAIEESADTFFYQVAFEMGIDRIHEWLSKFGYGQSTGIDLNEEYAGVLPSREW
                     KQRVHKKPWYQGDTISVGIGQGYWIATPIQMVKALTTLLNNGKVQDPHLLYSMKQGNHV
                     ERYQQPANLPQVGDPKSPYWGIVRNGMYGMANQPNGTGYKLFHTAPYQIAAKSGTSQVF
                     SLKQNQTYNAKMIPVRLRDHIFYTLFAPYQHPKVAMALILENGGGDGVVAGPTARAILD
                     "
     PFAM_domain     complement(16494..17015)
                     /aSDomain="PBP_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03717.17"
                     /description="Penicillin-binding Protein dimerisation
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2637_0115"
                     /evalue="1.40E-43"
                     /label="ctg1_2637"
                     /locus_tag="ctg1_2637"
                     /protein_end="238"
                     /protein_start="64"
                     /score="149.5"
                     /tool="antismash"
                     /translation="IAPSRGLIFDRNGIPLVQNITLYRLQVIPSKIHDMAALLQQLTPI
                     VDLTPDDIASFRDDMHHTSRYKAVTLKSDLSDVEVARFAVNEFRFPGVTVESYQQREYP
                     YGAELAHVVGYVSKINDSDLQRLAKNGEEENYAADRNIGKQGIEGYYEKALHGTTGYQE
                     VEVDNHGRVVR"
     CDS             complement(17406..17882)
                     /locus_tag="ctg1_2638"
                     /transl_table=11
                     /translation="MDTIVIILALCGGALLSVQAAINGRLGSQVGVLRSAFLTFATGAL
                     VTGLLILFFAPATSVNLLQVPKWQLLGAFCGVPYIVIMVLAVQRIGTATATVAVIFGQL
                     TMSLLIDNFGWLGNSTMAFSPARLAAVICLALALYLIYTSGKSATSHVAARAEQ"
     PFAM_domain     complement(17463..17870)
                     /aSDomain="DMT_YdcZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04657.15"
                     /description="Putative inner membrane exporter, YdcZ"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2638_0117"
                     /evalue="1.90E-31"
                     /label="ctg1_2638"
                     /locus_tag="ctg1_2638"
                     /protein_end="140"
                     /protein_start="4"
                     /score="109.3"
                     /tool="antismash"
                     /translation="VIILALCGGALLSVQAAINGRLGSQVGVLRSAFLTFATGALVTGL
                     LILFFAPATSVNLLQVPKWQLLGAFCGVPYIVIMVLAVQRIGTATATVAVIFGQLTMSL
                     LIDNFGWLGNSTMAFSPARLAAVICLALALYL"
     CDS             complement(17892..18326)
                     /locus_tag="ctg1_2639"
                     /transl_table=11
                     /translation="MALLFILLVIAGGMGLSVEAGLLGPLASQVGDLWATMSIFGIGAV
                     LTFFLMLFFSPRSSPSFFSLPGWQLTGGLLGAGYVVILTVATPVIGIAMTMIGILAGQI
                     AKSLAIDHYGLFGSPRRKIDPRRAMALMLIMAALLLVALG"
     PFAM_domain     complement(17907..18317)
                     /aSDomain="DMT_YdcZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04657.15"
                     /description="Putative inner membrane exporter, YdcZ"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2639_0118"
                     /evalue="1.40E-28"
                     /label="ctg1_2639"
                     /locus_tag="ctg1_2639"
                     /protein_end="140"
                     /protein_start="3"
                     /score="100.0"
                     /tool="antismash"
                     /translation="LFILLVIAGGMGLSVEAGLLGPLASQVGDLWATMSIFGIGAVLTF
                     FLMLFFSPRSSPSFFSLPGWQLTGGLLGAGYVVILTVATPVIGIAMTMIGILAGQIAKS
                     LAIDHYGLFGSPRRKIDPRRAMALMLIMAALLL"
     CDS             18426..19358
                     /gene_functions="regulatory (smcogs) SMCOG1031:LysR family
                     transcriptional regulator (Score: 259; E-value: 1e-78)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2640"
                     /transl_table=11
                     /translation="MADASSVDFRALQLFIAVYDNQSFSVVARREGVSPSLISRTIQQL
                     EDALGQQLFYRNTRAVVPTEAGRLFAASARELLGQYADAQRALQDRAQVPGGLVRINAP
                     VYFGQRHIAPWLPELAALHPKLQFDLTLTDDFIDPHRDATDILFRISSLPDAGYHARVF
                     GSQRYYLTASPEYVSRYGSPTSPEALHQHCTLVYGGSQGANRWLFRQREEAWVHYPLTP
                     LMTSNNADALLTSAIGGMGIVLFPDWMVSEALHNGTLVTLMDRYSAAISHTPSYIAAIY
                     PYTRHPSLNVRTVIDYFADVFGSPPYWQR"
     PFAM_domain     18450..18629
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2640_0119"
                     /evalue="1.20E-17"
                     /label="ctg1_2640"
                     /locus_tag="ctg1_2640"
                     /protein_end="68"
                     /protein_start="8"
                     /score="63.7"
                     /tool="antismash"
                     /translation="FRALQLFIAVYDNQSFSVVARREGVSPSLISRTIQQLEDALGQQL
                     FYRNTRAVVPTEAGR"
     PFAM_domain     18702..19328
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2640_0120"
                     /evalue="3.80E-32"
                     /label="ctg1_2640"
                     /locus_tag="ctg1_2640"
                     /protein_end="301"
                     /protein_start="92"
                     /score="111.5"
                     /tool="antismash"
                     /translation="QVPGGLVRINAPVYFGQRHIAPWLPELAALHPKLQFDLTLTDDFI
                     DPHRDATDILFRISSLPDAGYHARVFGSQRYYLTASPEYVSRYGSPTSPEALHQHCTLV
                     YGGSQGANRWLFRQREEAWVHYPLTPLMTSNNADALLTSAIGGMGIVLFPDWMVSEALH
                     NGTLVTLMDRYSAAISHTPSYIAAIYPYTRHPSLNVRTVIDYFADV"
     CDS             19627..21804
                     /locus_tag="ctg1_2641"
                     /transl_table=11
                     /translation="MSTSNDPSNNASAGKCPFHAETPKQSAGSGTANRDWWPNQLRVDL
                     LNQHSNRSNPLGENFNYREEFKKLDYSALKADLRALLTDSQEWWPADWGSYIGLFIRMA
                     WHGAGTYRTVDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPVKQKYGQKISWADLY
                     MLAGNVALENAGFRTFGFGAGREDVWEPDLDVDWGDEKEWLAHRHPESLAKQAIGATEM
                     GLIYVNPEGPNASGEPLSAAAAIRATFGNMAMDDEEIVALIAGGHTLGKTHGAAETSHV
                     GAEPEAAPLEAQGLGWHSSYGSGAGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQ
                     TRSPAGAIQFEAKDAPEIIPDPFNPEKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQA
                     FNEAFARAWFKLTHRDMGPKSRYLGPEVPKEDLIWQDPLPAATHQPSAEDIASLKTAIA
                     GAGLSVSELVSVAWASASTFRGGDKRGGANGARLALAPQKDWPVNAIASRVLPTLQAIQ
                     RASGKASLADIIVLAGVVGVEQAAAAAGVSVNVPFTPGRVDALPEQTDVESFDLLQPLA
                     DGFRNYRRIEGGVSTETLLIDKAQQLTLTAPEMTVLVGGLRVLGANYDGSKHGVFTDRV
                     GVLSNDFFVNLLDMATVWKAADDNAELFTGSDRKTGEAKYSATRVDLVFGSNSVLRALA
                     EVYACADGQQKLVHDFVAAWTKVMNLDRFDL"
     aSDomain        19696..21801
                     /aSDomain="TIGR00198"
                     /aSTool="tigrfam"
                     /description="cat_per_HPI: catalase/peroxidase HPI"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2641_0033"
                     /evalue="0.00E+00"
                     /identifier="TIGR00198"
                     /label="ctg1_2641"
                     /locus_tag="ctg1_2641"
                     /protein_end="725"
                     /protein_start="23"
                     /score="1262.2"
                     /tool="antismash"
                     /translation="KQSAGSGTANRDWWPNQLRVDLLNQHSNRSNPLGENFNYREEFKK
                     LDYSALKADLRALLTDSQEWWPADWGSYIGLFIRMAWHGAGTYRTVDGRGGAGRGQQRF
                     APLNSWPDNVSLDKARRLLWPVKQKYGQKISWADLYMLAGNVALENAGFRTFGFGAGRE
                     DVWEPDLDVDWGDEKEWLAHRHPESLAKQAIGATEMGLIYVNPEGPNASGEPLSAAAAI
                     RATFGNMAMDDEEIVALIAGGHTLGKTHGAAETSHVGAEPEAAPLEAQGLGWHSSYGSG
                     AGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAKDAPEIIPDPF
                     NPEKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKSRY
                     LGPEVPKEDLIWQDPLPAATHQPSAEDIASLKTAIAGAGLSVSELVSVAWASASTFRGG
                     DKRGGANGARLALAPQKDWPVNAIASRVLPTLQAIQRASGKASLADIIVLAGVVGVEQA
                     AAAAGVSVNVPFTPGRVDALPEQTDVESFDLLQPLADGFRNYRRIEGGVSTETLLIDKA
                     QQLTLTAPEMTVLVGGLRVLGANYDGSKHGVFTDRVGVLSNDFFVNLLDMATVWKAADD
                     NAELFTGSDRKTGEAKYSATRVDLVFGSNSVLRALAEVYACADGQQKLVHDFVAAWTKV
                     MNLDRFDL"
     PFAM_domain     19873..20814
                     /aSDomain="peroxidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00141.25"
                     /description="Peroxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2641_0121"
                     /evalue="6.50E-46"
                     /label="ctg1_2641"
                     /locus_tag="ctg1_2641"
                     /protein_end="396"
                     /protein_start="82"
                     /score="157.0"
                     /tool="antismash"
                     /translation="TDSQEWWPADWGSYIGLFIRMAWHGAGTYRTVDGRGGAGRGQQRF
                     APLNSWPDNVSLDKARRLLWPVKQKYGQKISWADLYMLAGNVALENAGFRTFGFGAGRE
                     DVWEPDLDVDWGDEKEWLAHRHPESLAKQAIGATEMGLIYVNPEGPNASGEPLSAAAAI
                     RATFGNMAMDDEEIVALIAGGHTLGKTHGAAETSHVGAEPEAAPLEAQGLGWHSSYGSG
                     AGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAKDAPEIIPDPF
                     NPEKKRKPTMLVTDLTLRFDPEFEKISRRFLND"
     PFAM_domain     20833..21720
                     /aSDomain="peroxidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00141.25"
                     /description="Peroxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2641_0122"
                     /evalue="4.50E-34"
                     /label="ctg1_2641"
                     /locus_tag="ctg1_2641"
                     /protein_end="698"
                     /protein_start="402"
                     /score="118.2"
                     /tool="antismash"
                     /translation="AFARAWFKLTHRDMGPKSRYLGPEVPKEDLIWQDPLPAATHQPSA
                     EDIASLKTAIAGAGLSVSELVSVAWASASTFRGGDKRGGANGARLALAPQKDWPVNAIA
                     SRVLPTLQAIQRASGKASLADIIVLAGVVGVEQAAAAAGVSVNVPFTPGRVDALPEQTD
                     VESFDLLQPLADGFRNYRRIEGGVSTETLLIDKAQQLTLTAPEMTVLVGGLRVLGANYD
                     GSKHGVFTDRVGVLSNDFFVNLLDMATVWKAADDNAELFTGSDRKTGEAKYSATRVDLV
                     FGSNSVLRALAEVYA"
ORIGIN
        1 cgcggcaacc agctggcgat ggccaccggc ctgaccaccc tgcgtcatct gcgcgacaac
       61 aagatcgccg acaaagtcgc cgcccagggc gagtggctga aaggtaaact ggccgagctg
      121 cagaaacgct acccggtgat tggccacgtt cgcggtctcg gtctgatgat cggtatcgaa
      181 atcgtcaagc cgaacgaagc gcaggatcac atgggctgct acccggctga cggcgaactc
      241 tctgccctgc tgcagaagaa atgcttcgaa gcgggcctga tcctcgagcg tggcggtcgt
      301 cacggctgcg tgctgcgcct gctgccgtcc ctgctgatca gcgacgcgga gctggacgtg
      361 ttcctcgaca aatttgaaca ggccctgctg gccgccggcg taaaaccggt ctgagtggag
      421 taagtgaccg ccatgtccac attgaatccg attcttgctg gttcagcgca gagcgttgaa
      481 gcctatcagc aggttatcga gcagaccagc caggccgttg tgcagtggct gaagcaacct
      541 gagatgtatc aggggaaaag cgttgacgag ctgcgtgagc gtatctccct tgaatttaac
      601 gaacagggtt tgggtaacca ggcggcgatt gatcgtgcga tcgagtactt cctgaaagat
      661 agcctgtcgg tgcatcaccc gcagtgcgtg gcgcacctgc actgcccgag cctggtgatt
      721 agccaggcgg cggaagtgct gattaacgcc accaaccaga gcatggactc ctgggatcag
      781 agcccgtcgg caaccattat cgagatgaag ctgatcgaat ggctgcgcgc ccgggtcggt
      841 tttccggcgg gcgacgccgg cgtcttcacc agcggcggca cccagagcaa cctgatgggc
      901 ctgatgctgg cgcgcgacgc cttcttcgcc cgtcaggggc actccatcca gcaggatggg
      961 ctgccggggg atatccgcaa gtacaaagtc ttgtgctcgg aaaacgccca cttctcggtg
     1021 cagaagaaca tggcgctgat gggcctcggc taccgctcgg taacgctggt gaaaaccgac
     1081 gaattcgcgc ggatggacgt gtccgacctg caggcgaaga ttgcgcaagc gcaggctaac
     1141 ggcgagcaga tcatggcgat cgtggccacc gccggcacca ccgacgcagg cgctatcgac
     1201 ccgctgcgcg acatcgccgg tatcgctgcg gaacatcaga tctggctgca cgttgacgca
     1261 gcctggggcg gcgccctgct gctgtctgag cagtatcgcg actaccttga cggtctggag
     1321 ctggtggatt ccgttaccct ggacttccat aagcagttct tccagaccat cagctgcggc
     1381 gcattcctgc tgaaggacgc gcgccattac gagctgatgc gttatcaggc ggcctatctg
     1441 aactccgagt tcgatgaaga acacggcgta ccgaacctgg tgtctaagtc gctgcagacc
     1501 acccgtcgct tcgatgcgct gaagctgtgg atgggtctgg aagcgctggg ccagaaacag
     1561 tatgcggcga tcatcgatca cggcgtcacg atggcgaaaa acgtggcgga gtacgtgaag
     1621 tcgcagccga cgctggagct ggtgatgcag ccgcagctgg cgagcgtgct gttccgttcc
     1681 cgtccggcgc agatggccgg gagcgacgcg gcggctatcg cgctgctcaa ccagcgcgtc
     1741 ggcgacgccc tgctggcctc cggccgcgct aacgtcggcg taaccgagca caacggcgtt
     1801 acctgcctga agctgaccct gctgaacccg gtggtgacgc tggatgacgt gaaggttctg
     1861 ctgaacctgg tggagcgcac cgctcaggag ctgctggcgc aataacctgc cttagcgagg
     1921 cggcgcctgc cgccccgctg tcagccttgc ctgcaataag ccgataatgt ccttatcggt
     1981 ctttttttat ttctttccgc accgctaatg ctctcttcgc agggcccgtt gacccctgcc
     2041 cctcgcgatg ccacagtact atcccgaaaa taacaacgtt caggataaac gtcctgaaaa
     2101 tggggatgat gatggagaaa cgcttaccag ggctggatct cgacgccctg cgcagctttg
     2161 tgaccggcat ggagtgcggc agtttcgccc aggcagcgct gcgcctgtcg cgttccacct
     2221 ccgcggtcag cgcccagctt aaaaagctgg agagtcagtg cggtgcggcg ctggtgacca
     2281 aacaggggcg ccatctggtg ctcaccgcgg aaggcgaaaa gctgatgagc tacgccagac
     2341 gcctgctggc gctcaatgat gaaaccctgc gcgcgctgca gggtgagcgg ctcaccggcg
     2401 agatccacct tggtatgcag gaagattttg gcgaatcgct gatgccggag atcctcgggc
     2461 aatttaaacg gcatcatccg caggtgcgga tagtcgccag ggtggatcgc aatggtccgc
     2521 tgcgccaggc gctggcggaa gaggcgctgg atctggcgct gctgtggcaa accgaagatc
     2581 agggttccgg gctgggcctc tgcccgctgg cgtggattgc gcatcctgac ctggatattc
     2641 gcgctctgct ggtctccggc gagccgctgc cgctggtgat gttcgacagc ccgtgcctga
     2701 tgcgctcccg cgccattgcc tgtctcgatg ccgcggggat cccctggcag gtggtgttcg
     2761 tcagccacag cctgagcggc atctgggcgg cggtgcaggc cgggctgggc ctgacgatac
     2821 gcacccgcat cggcatgcca ggcaacctgc gccccgcagg aggactcctg ccagctccag
     2881 gaagtctggc cgtcagcctg cgacaaaccc cgcgtgagga acaccattcc gccgccgtgg
     2941 cgctgctcgg cgaactgatg accgaggccc tgcagggatg gctcaacagg tgacactgtc
     3001 acgccatccc tgcgcgctga tgtaggccgg gcaagcgcag cgccgcccgg caatgggtat
     3061 aagggctgga gggttccgtc cgccagacgc ctgcgccgcg ggtcaggctt tgctctcctg
     3121 cagcagctgc tggatcacct gctcctggcg ggcataatcc ccttcgccga aggcggtata
     3181 acgcagctgt ccgcgagcgt cgaaaatgta atgcgccggc cagtactgat tgccgaaggc
     3241 attccagatg gcgtactcat tatccgccac caccgggtag gttatccgcc agtccttcac
     3301 cgcctggcgc agcaggggca acgaacgctc ccagggatat tccggggtat gaacgccaat
     3361 caccaccagg cccgccgcgc ggtatttgtt cgcccagtcg cgcacgtaag gcagggtatg
     3421 ctgacagttg atacactccc gggtccagaa atccaccagc accactttgc ccttcagacg
     3481 ctccggagtt aacgccgggc tgttgatcca tgcgctgccc cccgccagag agggcatcgc
     3541 gctgctgggc tgcggcgcgg cgatcggctg gaggctggtc ttttgctccg gctgcggcag
     3601 acgggcggcc agccgctgct ccagcgcctg gctcagtcca ccagcgcttt gcagatagcg
     3661 atcgccgccg ctagcgatca gcgccaccga ggccagcatt gccccccctg ccaaccggcg
     3721 cagccgttcg ccgaacgcct gtccgcgacg caatctggcg atcaacgccg ccccgcacca
     3781 ccccagcagg aataacatca gcgccccgcc gctgccgtag gccagcagca agccgccggt
     3841 agtcgcctgc cccggatgca caaagcccag gctaagtatc gctcccaata ccggcccggc
     3901 gcacggcgcc cacagcaggc ccaccgccag cccggccagt agagaaccga tccagccgcg
     3961 ctggcgtgaa ctggcatcgt taagctgatt ccccaacgct accaggggtg aggtcagccg
     4021 ttgcgcgacg cgttgcgaaa gcagactcag cccgaccagg gcgaagaacg ccagcgccag
     4081 accgcggcct gcgagggtca gattcaccac ccagccgctg gcgaccgtca ccagccagga
     4141 gacagcgccg aacatcagcg ccatgcctgc cagcatgatc gccagctgcc cccggcggcc
     4201 ccggacgctg gcgaacagca gcgggatcac cggcagcgta caggggctca gcagagttaa
     4261 catcccgccc aaaaatgcaa ttaatatcga catcgccttc tcctcattat gccatcgctg
     4321 ccgaaagtgg cagccacgac attacagcaa ggccatgtaa ggcgaatgtg tcgggaaagg
     4381 gggagaattg tcggcttagt tatccgtttt ccccgaagat acatcaggat acaatcccgc
     4441 cgcggcaagg cgaacgctgg cgtccaggcc gccctgcggg cggttggcca ggcgcagcgc
     4501 gccgtccatc tggctgacca gctgcgcggc gatcgccagc cccaggccgg tgccgccggt
     4561 atcgcgattg cgcgagtcct ccaggcgata aaacggctgc agcaccgcct gcagcgcggc
     4621 ctcggggatc cccggcccct catccagcac atgaagggtg atatccccca cggcgtcacg
     4681 ggtcagggtt accgtggccg tcgtaccgaa tttcaaggcg ttatcgataa gattggtcat
     4741 cacccggcgc agagcctgcg gcgggatcca caccaccccg gcggtctctt cgggacaaaa
     4801 ctggaccggc cggccgacat cggcataatc gcagacgatg gtgtcgagaa acgcatcgag
     4861 attcagccgc tgtcgcgcct cctccagcgg ctgcgaggtg cgggcgaagg cgatgccctc
     4921 ccgcaccaga cgggtcatat tgtcgagatc ctgcagtagc ttatcgcgca gttccggctg
     4981 gtcggccatc tccacccgca gcttcattcg ggttatcggg gtttgcagat cgtgggagat
     5041 ggcggcaagg atccgcgctc gctcctgcag atgatcgtgg atgcgcgcct gcatcgcgtt
     5101 aaacgcgcga gcggcgcgac gcacctcctc cggcccctgc tcggccatag ttcccgccgt
     5161 gtcgctggcc ggctccaggg catttaccgc gtgggtaaag cgggagatgg gcagcaatac
     5221 ctggcgaacc gcgtaccagg cgcaggccag caggaggaca aactgagcga tcagcaccac
     5281 cggcagccag cgggcgatgg ccggtagttt cggccacagg tcgagggtca acggcgcgcc
     5341 gtcgtgaagg gtaatatggg cctgaatatg ctgccgcggg ccggggatcg ccacaatact
     5401 taccggatac tgcgcgctca gcgcctcctg cagggagcgc gctgcgtccc gggcgcgcca
     5461 gttgtccggg taatcgccgc gctccccggc gtccagcaga tagcgataat tgccgcgcgc
     5521 cagcttcggc agccattgtg ggcgctcagc ggccggcagg cggtcaagga tcgccacgct
     5581 ggtggcgaca tcggaagcca gattgcccag catcacgctg cgagcgctgc tcatacgctc
     5641 ataaaacagc agcgacaggg ttaaggtatt cgccagcagc agcgccagaa acagcagcgc
     5701 catcagcctc gactgcagcg aggcgggcca gaacctcatt catgcctctc gcgaatggag
     5761 accggtaccg acagcatata gccttcgctg cgcaccgttt taatgtaggc cggctcgcga
     5821 gcatcctccc gtagccgctg gcgcagtcgg ctcaccagca ggtcaattga ccgctcaaac
     5881 agttccgcgt cgcgtccctg ggtcagattg agcagctgat cgcggttcag cacccgctgt
     5941 ggatggtcga gaaacacccg cagcagccga tactccgccc cgctgagggc gacgatggcg
     6001 ccgctgtcgt ccagcaaatg gcgagcggca gtgtcgagca gccagtcgcc aaaggcgatc
     6061 agcctgcccg cctcggtgat ctgcaggttc ggcggcagcg cccgggtgcg gcgtaaaata
     6121 gctttgatgc gcgccagcag ttcgcgagcc acaaagggct taatcagata atcgtcagcc
     6181 cccatttcca ggccgaggat ccggtcgctg tcatcggtgc gggcggtgag catcagcacc
     6241 gggatatcct gctgcgggtt agcgcgcagc tggcgacaga gcgttaagcc atcctctccc
     6301 ggcatcataa tatccagcac aatcaggtca atttgatggt ttttgagtac cgaccacatg
     6361 gctttgccgt tcgccgcgcc gctggcgcga tatcccgatt tttccagata gtcgacaatc
     6421 agttcccgga tgtcgcggtc gtcgtcgacg accaggatgt ggtcaatacg ctccaaaggc
     6481 tgctcctggg gcaaaataaa ctcttcacaa gcataagccg tgttgccgga agcgcaacgt
     6541 cgcgccgccg gcaaggcgcg ggttacaaac gatcggcgtc caccaccgcc tgcacaaacg
     6601 ccgtcggatc ctcctgcggc gggttatggc ccacagctcc cggcagatcc cggtgctcat
     6661 atttaccggt aaatttggca cggtagctgg cgggagccgg atgcggcgcg ccgttattcg
     6721 ccccttccag ggtgatggtg ggcacggtta tcggcggtag cgccgccagc cgttgttcat
     6781 agccggcata cttcgcttcc cctttctcca gccccaggcg ccagcggtag ttgctgatgg
     6841 tgatcgccac atggtccggg ttatccagag cccgggcggt tttggcaaag gtcgcgtcgc
     6901 tgaattgcca ctgcggcgac gcctgatgcc agataaattt cgcaaagtcg tgggtgtttt
     6961 gccggtaacc ggcctcccca cgcggggtgg caaaatagaa ttgataccac cacgacagct
     7021 cagcctgcgg cggcagcggt ttttcgccaa tctgctgact gctgatcaga tacccgctca
     7081 ccgagaccag ggatttcacc cgctgcggcc acagcgcggc gacgatatcc gccgtgcgcg
     7141 cgccccagtc aaaaccggcc agatccgcct gcctgatgtt aagggcgtcc atcagatgga
     7201 caatatcggc cgccatcgcc gacggctgac cgttacgcgg cgtgctggcg gagaggaaac
     7261 gggtcgtgcc gtagccgcga agatacggca cgatcacccg gtaacccttc tgcgctagag
     7321 ccggcgccac ctgggcatag ctctgaatgt cgtagggcca gccgtgcagc aggatcaccg
     7381 gctggccgtc gcgtgggccg atatccacgt agccaatatt caggtcgccg gcgcggatct
     7441 gctggatctt gtcgaacgcc cccgcgtctt cagcggcgca aacggcggcg gaccacaggg
     7501 tggataaccc cagcgccacg gcgctggtat agcggatcag ggataatctg ttcatcgttt
     7561 tctcaccttt tatcgtcatc aagagagtac gtgaccagta aagcggaaat ttgtatccgc
     7621 catgtgcccg accggggcca tttttctctc ttaatgtcag cgcagcaccg cgagatacag
     7681 tgtgatacaa agtcgaggtt ggcaattgtt gcgggcatgt gaatttatgc ttgccccggg
     7741 agataaatcc gttaccgtgg caggcatttt tcaccactta agaacgcagg aacccgctat
     7801 ggcgattttt gatggtcaca atgacctgct gctgaatctc tggcttcacc atcgcgagga
     7861 tccggtgagc gccttctttg ccgggataga gaacggccat ctcgactatc cgcgcatgct
     7921 gcaaggcgga tttgccggcg ggctattcgc gctattcgtg ccaccgcagg aatatattgc
     7981 ccgtatgacg ccgcaatacg ccagccaacg atgggatccg atcgatatcc tctggcagca
     8041 actggccatc ctgaagcaac ttatcgcgca ctccgctgga cgcttgagat tgtgtctgag
     8101 cgcggcggat atcgagcgct gccgcgagga taaggtactg gcgatggtgg cgcatattga
     8161 gggtgccgga ggttttgatg gcgagggccg cgacctgcag gccttttatg ccgccggggt
     8221 ccgcagcatt ggtccgttct ggaatattgc gaaccgcttc ggcagcggcg ttaacggttc
     8281 gtttcccggt agcccggaca ctgggcctgg actgacagcg gcaggtatcg atctgattaa
     8341 gcaggtcaat gccttgaaga tgcagattga cgtgtctcat atgaatgaaa aagcgttctg
     8401 ggataccgcc catcacgcaa cgtcaccgct ggtggccacc cactccaatg cccatgccct
     8461 gtgcccgcag ccgcgcaatc tgaccgacca gcaactgcgg gcgatccgcg acagcggcgg
     8521 cgtggtgggc gtcaatttcg gcaatgcttt cctgcgcgcc gacggccggc gcgatagcga
     8581 cacgccctta accaccattg tccggcatat cgactatctt attaacataa tgggtgagga
     8641 tcatgtggcc cttggctcgg attttgacgg catcaccctg ccggacgagc tgggcgatgt
     8701 ggccggctta ccgcggctta tcaatacgtt gcgcgctagc ggctatgatc aattggtgct
     8761 ggataagctg ctgtggcgta actggctacg ggtattaaaa aatgtttggc aacaataggt
     8821 tatattgtaa acataaagtt aattccttac agattccggg ttgatctctc tcccggtgaa
     8881 gcgcaatatg cggcagccgt cacagatcca ccattatccg tgaggcctgt agtcattttt
     8941 aagaggaaca aaacatgtgg aagaaacctg cttttatcga tttacgtctc ggtctggaag
     9001 tgacgctgta catttctaac cgttaatcgc cccgcccgcc gttcgcgcgg gcaccttcat
     9061 tcattacccg gtccgtcttc atgttcatta aagtcctcgg ttccgccgcc ggcggcggtt
     9121 tcccgcaatg gaactgcaac tgcgccaact gtcagggtct gcgcgatggc accattcagg
     9181 ctgccccccg cacccagtcg tcaattatcg tcagcgacaa cggtaaagag tgggtgctgt
     9241 gcaacgcctc gccggatatc agccagcaga ttgccaatac ccccgagtta aataaagccg
     9301 gcgtactgcg cggaacgcat atcggcggca ttattctcac cgacagccag atcgaccaca
     9361 caaccgggtt gctgagcctg cgggaaggct gcccacatca ggtctggtgc accccggagg
     9421 ttcatgagga tctctccacc ggcttcccgg tgtttaccat gctgcggcac tggaacggcg
     9481 gcctggtgca tcatcccatc gctccgcagc agccttttac cgttgacgcc tgtcctgatt
     9541 tgcagtttac cgcggtgcct atcgccagca acgcgccgcc ctattcgccg tatcgcgacc
     9601 ggccgctgcc gggtcataac gtggcgctgt ttatcgaaaa ccgccgcaac gggcagacgc
     9661 tgttctatgc cccggggctg ggtgagccgg atgaaaccct tctgccgtgg ctgcaaaaag
     9721 cggactgtct gctgatcgat ggcaccgtct ggcaggatga cgagctgcag gccgccggcg
     9781 tcggacgcaa taccggccgc gatatgggcc acctggcgct cggcgacgag cacgggatga
     9841 tggccctgct ggcctctctg ccggcaaaac gcaaaattct cattcatatt aataacacca
     9901 acccgatcct taacgagcag tctccccagc gccaggcgct aacgcaacag gggatcgaag
     9961 tgagctggga cgggatggca atcacccttc aggataccgc atgctgatca ctgacacgct
    10021 gtcgccgcag gcctttgaag aggctctgcg ggctaaaggc gccttctacc atattcacca
    10081 cccttaccac atcgccatgc ataacggcga cgcgacccgc gagcaaattc agggttgggt
    10141 ggcgaaccgg ttttattacc agaccactat tccgctgaaa gacgcggcga ttatggccaa
    10201 ctgcccggat gcgcaaaccc ggcgcaaatg ggtgcagcgg atcctcgacc acgacggcag
    10261 ccacggcgag gacggcggga ttgaagcctg gctgcggctg ggggaagcgg tcggtttgag
    10321 ccgcgacgat ctgctcagcg agcgtcacgt gctgcccggc gtgcgcttcg cagtggatgc
    10381 ctatctcaat ttcgctcgtc gcgcctgctg gcaggaggcg gcctgcagct ccctgaccga
    10441 gctgttcgcc ccgcagatcc atcagtcgcg cctcgacagc tggccgcagc actatccatg
    10501 gatcaaagag gaaggctact tttacttccg cagtcgtctg agccaggcca atcgcgacgt
    10561 tgagcatggc ctggcgctgg cgaaggccta ctgtgacagc gctgaaaaac agaaccggat
    10621 gctggagatc ctgcagttta agctcgacat tctgtggtcg atgctcgatg ccatgaccat
    10681 ggcctatgcc ctgcagcgcc cgccctatca cacggtcacc gacaaggcgg cctggcacac
    10741 gacccgactg gtgtaatcat gcaaaaaacg tccatcgttg cctttcgtcg cggctaccga
    10801 ctgcagtggg aagccgccca ggagagccat gtgatcctct atccggaggg tatggccaaa
    10861 ctcaatgaga ccgccgcggc gatcctcgag ctggtcgatg gccggcgcga cgtcgcggcg
    10921 attatcgcca tgcttaatga acgtttcccg gaagccggcg gcgtcgatga cgacgtcatc
    10981 gagttcctgc agatcgcctg tcaacagaag tggatcacct gccgtgagcc agagtaaacc
    11041 caccgtcaat ccgccactgt ggctgctggc ggagctgacc taccgctgcc cgctgcagtg
    11101 tccctactgt tccaatccgc tggacttcgc ccggcaggat aaggagctga ccaccgaaca
    11161 atggatcgag gtctttcgcc aggcgcgggc gatgggcagc gttcagctgg gcttttccgg
    11221 cggcgagccg ctgacccgta aagatctgcc ggagctgatc cgcgccgcgc gcgacctcgg
    11281 gttctatacc aacctgatca cctccgggat agggctgacg gagagcaaac tggacgcctt
    11341 cagcgaggcc gggctggacc atatccagat tagcttccag gccagcgatg aagtgctcaa
    11401 cgccgcgctg gccggcaaca aaaaagcctt ccagcagaag ctgaccatgg ccaaagccgt
    11461 gaaagcgcgc gactacccga tggtgctcaa cttcgttctc caccggcaca acatcgacca
    11521 gctcgataaa attatcgagc tgtgcattga gctggaagcc gatgacgttg agctggccac
    11581 ctgccagttc tacgggtggg cgtttcttaa tcgcgaaggg ctgctgccga cccgggaaca
    11641 gatcgcccgc gccgagcagg tggtcgctga ctaccggcag aaaatggccg ccagcggcaa
    11701 cctcaccaac ctgctgttcg tcaccccgga ctattacgaa gagcggccga aaggctgcat
    11761 gggcggctgg ggatcgattt tcctcagcgt caccccggaa ggcaccgccc tgccttgcca
    11821 cagcgcgcgc cagctgccgg tggcgtttcc gtcggtgctg gagcagagtc tggaatcgat
    11881 ctggtatgac tcattcggct tcaatcgcta ccgcgggtat gactggatgc cggagccgtg
    11941 ccgctcctgt gatgaaaaag agaaggactt cggcggctgc cgctgccagg cctttatgct
    12001 gaccggcagc gccgataacg ccgacccggt gtgcagcaaa tccccgcatc atcacaaaat
    12061 cctcgaggcc cggcgcgaag cggcctgcag cgacataaaa gtcagccagc tgcagttccg
    12121 caaccgtacc cgctcgcagc tgatcttcca aacccgggac ctgtaatgac gctggcgacc
    12181 cgcaccgtca ctttgccggg cggcctgcag gccaccctgg tccatcagcc gcaggcggat
    12241 cgtgcggctg ccctggcgcg ggtcgccgcc ggcagccacc acgaaccgtc gcgcttccct
    12301 gggctggcgc acctgctgga acatctgctg ttttacggcg gagagcgcta ccaggatgat
    12361 gaccgactga tgggctgggt gcagcgccag ggcggaagcg tgaatgccac caccctggct
    12421 cgccatagcg cgttcttttt cgaggttgcc gccgatgctc tggctgatgg tgtcgcgcgt
    12481 ctacaggaga tgctgcaggc cccgctgctg ctcagggaag atattcagcg cgaagtggcg
    12541 gtgattgacg ccgagtaccg cctgatccag cagcatgagc catcgcgccg ggaagccgcg
    12601 gtgcgccacg ccgccagcgc gcccgcggcg tttcgccgct ttcaggttgg cagcgccgac
    12661 gcgctggcgg gcgatctcgc tgcgctgcag gccgccttag gcgattttca ccgcacccat
    12721 tacgtcgccc ggcgaatgca gctctggctg caggggccgc agtcgctgga ggctctcggc
    12781 gagctggcgg cccgttcgcc gccgggcttg ccgcaggcga ggctccgccg ccggcgccgc
    12841 cgctgcgcct gggcgagttc actgcactgc agctggcggt ctccagccag cccgcgctgt
    12901 ggcgctgccc gctgatcgct ttaagtgaca acgtcacgtt actgcgcgag tttttgctgg
    12961 atgaagcccc cggcagcctg atggccggcc tgcgccagcg ccggctggcc ggggatgtgg
    13021 cgctgaactg gctgtatcag gatcggcacc tcggctggct ggcgctggtc ttcgccagcg
    13081 accggccgga agaggtcgac cggcagataa cccactggct gcaggcgcta cagcaaacga
    13141 cgcctgagca gcagctacac tactatcagc tatcccggcg ccgctttcag gcgctgtcgc
    13201 ctctcgatca gctgcgccag cgggcattcg gctttgcccc cggcgcgccg cccgccgggt
    13261 tcgccgattt ttgcgccgcc ctgcaggccg ccccgtcggt cagactggcc tgtcagaccg
    13321 tttccccagg ggagcctgtt gccacccagg gctttagcct gccgcttagc cgctggcgcc
    13381 gccgccctga gtctgacccg gcgctggcgt tcgcttttta tccgcaggcc gctggcgatc
    13441 tcgttgccaa atgcccggag gaagccgcgc cgctgctcca cctcccgtca ccgggagagc
    13501 cgccgaggct cctgctgcga ccgcccttct actgctcgcc cgatcaggcc gaaggactgg
    13561 cgcgtgggga acagctgcgc ccacagcttg ccgccctgcg ccatgccggg ggacacggcg
    13621 agtggcatct gttcgacggc agctggcagt tgaccctcca gctgccggag ccaggccgac
    13681 ggccggaggc gatcctgcag gccatcctgc ggcagctcgc gctcccggtc gcctcgctga
    13741 ccccaccgcc ggaaagtatc gctatccgtt atctcatggc tcaactcccc gaacggctgg
    13801 gtacatgcgg gcatcagaaa ggttggctgg cggccctggc cggcggcagc gcagaagatg
    13861 cgcagtggat agcgcgtcag ctgagcctga ttaccgcccc ggttaatccg ccgatgcccg
    13921 ctccggcgcc ctgccgccgc ggcgtcgaac gtctggttta tccgggaggc gatacggcgc
    13981 tgctggtctt tattccgctg ccggatggcg cctcgctggc ggccctgcgg ctgctggcgc
    14041 agcattgtga gccgctattt ttccagcgcc tgcgggtgga gcagcagatt ggctatgtgg
    14101 tgagctgccg ctatcagcgg gtcgccgatc gcgacgggct gctgatggcg ctccagtccc
    14161 cggatcgccg cgccggggaa ttgctgcgct gtggtaaaga ctttctgcgc cagctggccc
    14221 ccatggatga ggcgaccttc agaccgctac agcagcgcct ggccgctcag atccgcgcca
    14281 gcaggccgcc agaggcgcgg gcgctgtccg ccctgcgtca ggagtatggt ttaccagagc
    14341 taacgccgca ggcggtcgac gcgctgcgcg ttgcagaggt ggccgatctg gcacgcgaaa
    14401 tgacccgccg gcgtcgccgc tggcaggtgc tattcacgac aggggattaa tggccggggg
    14461 catccggggt cagaaaggcg ctgacgaagc gcgtaaggat cgccgcgccc tgcgggctct
    14521 cctgcacctc ttcgtgtaac cgctgcgcgt caataccttc cgcctgcagc accgcctccc
    14581 ggtggcggat cagcgaacgg gctatcggcg cggtaaattc cgggtgaaat tgcgtagaga
    14641 ccgcgtgagg cccatagcgc acaatctggt ggggatcgtg ggcggacgcg gccagcaccg
    14701 tggccccttc cggcagacga gtcacggttt gcaaatggct cagatgcgca ggaaatgtag
    14761 ccggcaggcc gctcagcagc ggatcatcga caccccatgg cgacagcgta atggtttggc
    14821 tgccgctttc ccgcccgcca ggatgatacg ccacctcgcc ccccagggca tgggccatca
    14881 gctgatgacc ataacaaacg ccgaacagcg gcatgtcgat agccaccgcc tgccggatcc
    14941 agtcggcggt ccgttcgctc cacgccagac gatcggttac catcgcccac gagccggtta
    15001 gcaccgctaa ggtttggtta tccggcgtcg gcagcggttc atcttcaaac acccgcaccg
    15061 tggtgagctg cgtctgccac ggcgccagca gcgtgcgaaa ccagcgcggc agatcgccat
    15121 gcgcctggcg aatggccgtc ggcggcgtgc cggtctggac cagcagtaat cggttacgtg
    15181 tcacctttcc tcctcgctcc gggtcatgtt cccgtaaaac actatgccgc cgggaagacg
    15241 atgggacaaa taaccaatta ctatggacga tgcgcctgcg gaataagtcc tgtcgcttac
    15301 tgggcatcgg cgctatcacg ctgcggcaca tcggctgccg ccgaagatgc ctgctgcggg
    15361 acaaaaatat ggtccaggat ggcgcgcgcc gtcggtccgg ccaccacccc atccccgccg
    15421 ccgttctcca gaatcagcgc catcgccacc ttcggatgct gataaggggc aaacagggtg
    15481 tagaagatat ggtcgcgcag acgcaccggg atcattttgg cgttataggt ctggttttgc
    15541 ttcaggctaa agacctgcga ggtcccggac ttcgccgcga tctgatacgg cgcagtatga
    15601 aacagcttat agccggtgcc gttgggctga ttcgccatcc catacatgcc gttgcgcaca
    15661 atgccccagt acggggattt cgggtcaccc acctgcggca ggttcgccgg ctgctgataa
    15721 cgttccacat ggttgccctg cttcatcgaa tagagcagat gcggatcctg tactttacca
    15781 ttgttcagca gagtggtaag cgccttcacc atctggatcg gggtggcgat ccagtacccc
    15841 tggccgatgc cgaccgagat ggtgtccccc tgataccagg gctttttatg cacccgctgt
    15901 ttccactccc ggctgggcag caccccggcg tactcctcat taaggtcgat gccggtggac
    15961 tggccgtagc cgaacttgct cagccattca tggatccggt caatgcccat ctcgaaggcg
    16021 acctgataga aaaaggtgtc cgctgactct tcgatggctt tagtcacgtt gagcatgccg
    16081 tggccggttt tcagccagtc gcggtagcgg cgttgcgtgc ccggcagcgt ccacgtcggc
    16141 gccccgaaga aggtggtgtt cggggtgatg accccagcgg agagcgccga cagcgccata
    16201 tagggtttga ccgtcgaagc cggaggatat agcccctggg tgacgcggtt gatcagcggc
    16261 cggtccggat tctccagcag cgatttatag gcctgatagc cgataccttt gacgaacgga
    16321 ttaggatcgt agctgggact ggagaccatc gccagcacgc cgccatcccg cgggtcgacc
    16381 accaccaccg ccgcccgctg tcccttcagc accgactcaa tatactgctg gagatgaagg
    16441 tcgagagtca gatagaggtt ttttccggcc accggcggca cctctttcag tagacgcacc
    16501 acccggccgt ggttatccac ctccacttcc tgatagccgg tggtgccgtg gagcgctttt
    16561 tcataatagc cctcgatgcc ctgcttaccg atattgcggt cggcggcgta gttctcctct
    16621 tcgccgtttt tcgccagccg ctgcagatcg ctgtcgttga ttttcgacac atagcccacc
    16681 acgtgcgcca gctctgcgcc gtaggggtat tcccgttgtt ggtagctctc caccgtcacg
    16741 ccggggaaac ggaattcgtt gaccgcgaag cgggccacct ccacatcgct gaggtctgac
    16801 ttgagggtga ccgctttgta gcggctggtg tggtgcatat cgtcgcgaaa gctggcgatg
    16861 tcgtccggcg tcaggtcgac gataggcgtc agctgctgca acagcgcggc catatcgtga
    16921 attttgctcg ggatcacctg caggcgatac agggtgatat tctgcaccag cggaatgccg
    16981 ttgcgatcga atatcagccc gcggctgggg gcgatgggca gcattttgat gtcgttctgg
    17041 tttgaccggg tctggtaaaa atcgtgctgc tccacctgca gatggtagag gttaacgatc
    17101 agcacgccaa agcagaccac caccagcaga aaagcaattg cggcccggcg gataaacagc
    17161 atctcttccg cggagtggtc gcgaatttcg tctctcaaaa ggggcattag cggtacatca
    17221 cctgaatcac tggaaaagcc aacggcgtaa cggccgggaa gcatagcctt atcgcagcgt
    17281 cagccctact gaaaggttgc taatgatctg gcagaaatgt ttcagcatgt tagagggatc
    17341 gttattctta accttgcccg tgacgcgtca ggctatattc acgatgcccg acgcgtcggc
    17401 gcagctcact gttctgcgcg ggccgccacg tgggaggtag ccgacttccc tgaggtatag
    17461 attaagtaca gcgcgagggc cagacatatc accgccgcca gtcgcgccgg cgagaacgcc
    17521 atcgtgctgt tgcccagcca gccaaagttg tcgatcagca ggctcatcgt cagctggcca
    17581 aagatcaccg ccacggtggc cgtagcggtg cctatccgct gcaccgccag caccataatg
    17641 acgatgtagg gcacgccgca aaatgcgccc agcagctgcc acttaggcac ctgtagcagg
    17701 tttaccgacg tcgctggagc aaaaaacagg atcagcaatc ccgtcaccag cgcgccggtg
    17761 gcgaaggtta aaaaggcgct gcgcagcacc cccacctggc tgccaagacg gccatttatc
    17821 gccgcctgga cgctaagcaa tgcgccgccg cacagtgcca gaatgatcac tatcgtatcc
    17881 atttcccctc cttaacccag agccaccagc agtaacgccg ccataatcaa catcagcgcc
    17941 atggcgcgcc gcggatcgat tttgcgccgt gggctaccga ataacccgta atggtcgatc
    18001 gccaggcttt tcgcaatctg acccgccagg atgccgatca tggtcatggc aataccaatc
    18061 accggcgtcg ccacagtcaa gatcaccacg taccccgccc ccaacagacc gccggtgagt
    18121 tgccagccgg gcagagaaaa gaacgacggg ctgctacgcg ggctgaaaaa gagcatcaga
    18181 aaaaaggtta acactgcgcc aatcccaaag atgctcatgg ttgcccacag atcccccacc
    18241 tggctcgcca gcggccccag caggccggcc tcgaccgata atcccatgcc gccggcaatc
    18301 actaataaaa tgaataataa cgccattact gcgcctcctc tgtacaacag gcggctgagg
    18361 ataaaacagc gtgctgatgc gataaacggt ataatgcaga aaacactatt gcaggaattg
    18421 cacagatggc cgatgccagc agcgtcgatt ttcgcgccct tcagcttttc atcgcggttt
    18481 acgataacca gagtttttcc gtagtggccc gccgcgaagg ggtctctccc tcgctgatct
    18541 cgcgaaccat ccagcagctg gaagatgccc tcgggcagca gctgttctac cgcaacaccc
    18601 gtgccgtggt accgaccgaa gcaggacgcc ttttcgcagc gtccgcccgg gaactgctgg
    18661 gacagtacgc cgacgcgcaa cgggcgttac aggatcgggc acaggtcccc ggcgggctgg
    18721 tgcggatcaa tgcgccggtc tattttggtc agcggcatat cgccccctgg cttccggaac
    18781 tggcggccct gcatcccaaa ctgcagtttg acctgacgct gaccgacgat tttatcgatc
    18841 cccatcgcga tgcgacggat atcctttttc gcatcagcag cctgccggac gcgggctatc
    18901 acgccagagt gtttggcagc cagcgctatt acctgaccgc ctccccggag tatgtttcac
    18961 ggtacggcag cccgacttcg ccggaggcat tgcatcaaca ttgcacgctg gtgtatggcg
    19021 gttcgcaggg agccaaccgc tggctgtttc gccagcgcga agaggcatgg gtgcactatc
    19081 cgttgacccc gctcatgacc tcgaacaatg ccgatgccct gctcacttca gccatcggcg
    19141 ggatggggat cgtgttattt cccgactgga tggtcagcga ggcgctgcac aacgggacat
    19201 tagtcacgct gatggatcgc tattcggcgg ccatcagcca cacgccatcg tatatcgcgg
    19261 cgatttatcc ttatacccgc catccctctc tcaacgtgcg gacagtgatt gactattttg
    19321 ccgacgtgtt tggatcgccg ccctactggc agcgctaatg cgagtttcgt agtaaaactt
    19381 gtcatatctc aaacaattag catttcttcg cccagcttga cgcggatcgt ttcctttgcc
    19441 gcctcgttac ggctatggtt actaatgagg ttaatctcaa tctccaggcc gacacggtcc
    19501 caccaggggg ttgcctaacc cttcattgaa cggaaatagc tattaaatcc gtagattcat
    19561 tcaaatatcg cttattggta gcagtgtata tcgtaacggc attcacaaaa gcaaacggag
    19621 cctgatatga gcacgtctaa cgacccatcc aacaatgcat ccgccgggaa gtgccctttc
    19681 cacgccgaga cgccaaaaca gagcgccggc agcggcaccg ccaaccgcga ctggtggccg
    19741 aaccagctgc gtgtcgatct gttaaaccag cactccaatc gctccaaccc gttgggtgag
    19801 aattttaact acagggaaga gtttaaaaag ctcgattact ccgcgctgaa ggctgatctc
    19861 agagcgctgc tgaccgattc gcaagagtgg tggccggcag actggggtag ctatattggc
    19921 ttgtttattc gtatggcctg gcacggcgcc ggcacctacc gcaccgttga cggtcgcggc
    19981 ggcgcaggtc gtggacagca gcgctttgct cccctgaact cctggcctga caacgtcagc
    20041 ctcgataagg cccgccgtct gctgtggccg gtgaaacaga aatatggcca gaaaatctcc
    20101 tgggccgacc tttacatgct ggcgggtaac gtcgctctgg aaaacgctgg cttccgcacc
    20161 tttggctttg gcgccggtcg cgaagacgtc tgggaaccgg atctcgacgt cgactggggc
    20221 gatgagaaag agtggctggc ccaccgtcat ccggaaagcc tggcgaaaca ggccatcggt
    20281 gccaccgaaa tgggtctgat ttatgtcaac ccggaaggtc cgaacgccag cggcgagccg
    20341 ctgtccgccg cggcggccat tcgcgccacc ttcggcaata tggcgatgga cgatgaagag
    20401 atcgtcgcgc tgatcgccgg cggccatacg ctgggcaaaa cccacggcgc cgcagaaacc
    20461 agccacgtcg gcgccgagcc ggaagccgcg ccgctggaag cgcagggtct gggctggcac
    20521 tccagctacg gcagcggcgc aggcgcggac gccatcacct ccggtctgga agtggtctgg
    20581 acgcagacgc ccacccagtg gagcaactac tttttcgaaa acctgttcaa atacgaatgg
    20641 gtgcagaccc gcagcccggc tggcgcgatc cagttcgaag ccaaagacgc gccggagatt
    20701 atcccggatc cgtttaaccc ggagaaaaag cgcaaaccga ccatgctggt caccgacctg
    20761 accctgcgct tcgacccgga gtttgaaaaa atctcccgcc gcttcctcaa cgatccgcag
    20821 gcctttaacg aggcgttcgc ccgggcgtgg ttcaagctga cccaccgtga tatggggcca
    20881 aaatcccgtt acctcgggcc ggaagtgccg aaagaagatc tgatttggca ggatccgctg
    20941 ccggcagcga cccatcagcc gagcgcggaa gatatcgcca gcctgaaaac cgccatcgcc
    21001 ggcgccggcc tgtcggtcag tgagctggtc tcggtcgcct gggcgtccgc ctccaccttc
    21061 cgcggcggcg ataaacgcgg cggcgctaac ggcgcgcgtc tggcgctggc cccgcagaaa
    21121 gactggccgg ttaacgccat cgccagccgg gtgctgccga ccctgcaggc gatccagcgc
    21181 gcctccggca aagcgtcgct ggccgatatt atcgtgctgg ccggcgtggt cggcgttgag
    21241 caggcggccg ctgccgccgg cgtcagcgtc aatgtgccgt ttaccccagg ccgcgtcgac
    21301 gctctgcctg agcagaccga cgtcgagtcg tttgatctgc tgcagccgct ggcggatggc
    21361 ttccgcaact atcgccgtat cgaaggcggt gtctcgacgg aaacccttct gatcgataaa
    21421 gcgcagcagc tgacgctaac cgccccggaa atgaccgtgc tggtcggtgg cttgcgcgta
    21481 ctgggcgcga actacgacgg cagcaaacac ggggtgttta ccgaccgcgt cggcgtgctc
    21541 agcaatgact tcttcgttaa tctgcttgat atggctaccg tctggaaagc ggccgatgat
    21601 aacgcggagc tgtttaccgg cagcgaccgt aaaaccggcg aagcgaagta cagcgccacc
    21661 cgcgtggatc tggtgtttgg ctccaactcg gtactgcgcg ccctggcgga agtgtacgcc
    21721 tgcgccgacg ggcagcagaa gctggtgcat gacttcgttg ccgcctggac caaggtgatg
    21781 aacctcgacc gcttcgatct gtaatcccct cgccccggct cccgccgggg cgtttttctt
    21841 ataccgcccg cggcagctgt tgcaggcgac tccgcgttcg ttgaatatcc tccagttcca
    21901 ccccttccac cagcgtctcc aggtcgcagc gggtcaccag cagcaggcgg atctgctttt
    21961 catacagcac atcaatcaca ttgataaagc gctgctgggt cgccggcccc accgtagcca
    22021 atggcggcac ctcgtccagt agccagacgg catagctttc gcagagcgtc agatagtcca
    22081 tcaccgccgt ggcggcctga caaagctggg taaaggtgaa gtgcagcaac gcgggcgacg
    22141 ccgcggccgc cagcagcgtg cgatag
//
