LOCUS       NC_016845.1            10624 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_016845.1 Klebsiella pneumoniae subsp. pneumoniae HS11286
            chromosome, complete genome.
ACCESSION   NC_016845
VERSION     NC_016845.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:53:27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 18891
            Orig. end    :: 29515
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10624
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[23891:24515](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5624
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10624
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10624
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(2486..2992)
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MIPLLAIAAWSGTGKTTLLKRLIPELCALGLRPGLIKHTHHDMDV
                     DKPGKDSYELRKAGAAQTIVASEQRWALMTETPEKPELDLTWLVSRMDASKLDLVLVEG
                     FKHEPVPKILLFRQNSGHRVEELVIDEHTIAVASDVSIATSLPLLDLNDVPQIATFIVS
                     WLERQ"
     aSDomain        complement(2501..2980)
                     /aSDomain="TIGR00176"
                     /aSTool="tigrfam"
                     /description="mobB: molybdopterin-guanine dinucleotide
                     biosynthesis protein B"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_15_0001"
                     /evalue="1.30E-50"
                     /identifier="TIGR00176"
                     /label="ctg1_15"
                     /locus_tag="ctg1_15"
                     /protein_end="164"
                     /protein_start="4"
                     /score="169.4"
                     /tool="antismash"
                     /translation="LAIAAWSGTGKTTLLKRLIPELCALGLRPGLIKHTHHDMDVDKPG
                     KDSYELRKAGAAQTIVASEQRWALMTETPEKPELDLTWLVSRMDASKLDLVLVEGFKHE
                     PVPKILLFRQNSGHRVEELVIDEHTIAVASDVSIATSLPLLDLNDVPQIATFIVSW"
     PFAM_domain     complement(2576..2980)
                     /aSDomain="MobB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03205.16"
                     /description="Molybdopterin guanine dinucleotide synthesis
                     protein B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_15_0001"
                     /evalue="2.20E-48"
                     /label="ctg1_15"
                     /locus_tag="ctg1_15"
                     /protein_end="139"
                     /protein_start="4"
                     /score="163.7"
                     /tool="antismash"
                     /translation="LAIAAWSGTGKTTLLKRLIPELCALGLRPGLIKHTHHDMDVDKPG
                     KDSYELRKAGAAQTIVASEQRWALMTETPEKPELDLTWLVSRMDASKLDLVLVEGFKHE
                     PVPKILLFRQNSGHRVEELVIDEHTIAVASD"
     CDS             complement(2989..3570)
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MQSEAITGVVLAGGRATRMGGIDKGLQALNGRPLWRHVAEALAPQ
                     VDELVISANRHLEQWRASGFPVFRDIQEGYQGPLAGMLAVMQQVASPWFVFCPCDTPFI
                     PSFLVERFIQQRGDAPVVWAHDGERDHPAVALVHRQIIPELEAYLAHGERRVMVFMRQM
                     GGRPVNFSDVKTAFINVNTLEDLQQMQEPS"
     aSDomain        complement(3010..3555)
                     /aSDomain="TIGR02665"
                     /aSTool="tigrfam"
                     /description="molyb_mobA: molybdenum cofactor
                     guanylyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_16_0002"
                     /evalue="3.50E-69"
                     /identifier="TIGR02665"
                     /label="ctg1_16"
                     /locus_tag="ctg1_16"
                     /protein_end="187"
                     /protein_start="5"
                     /score="230.5"
                     /tool="antismash"
                     /translation="ITGVVLAGGRATRMGGIDKGLQALNGRPLWRHVAEALAPQVDELV
                     ISANRHLEQWRASGFPVFRDIQEGYQGPLAGMLAVMQQVASPWFVFCPCDTPFIPSFLV
                     ERFIQQRGDAPVVWAHDGERDHPAVALVHRQIIPELEAYLAHGERRVMVFMRQMGGRPV
                     NFSDVKTAFINVNTLEDLQ"
     PFAM_domain     complement(3097..3549)
                     /aSDomain="NTP_transf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12804.9"
                     /description="MobA-like NTP transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_16_0002"
                     /evalue="5.60E-35"
                     /label="ctg1_16"
                     /locus_tag="ctg1_16"
                     /protein_end="158"
                     /protein_start="7"
                     /score="121.1"
                     /tool="antismash"
                     /translation="GVVLAGGRATRMGGIDKGLQALNGRPLWRHVAEALAPQVDELVIS
                     ANRHLEQWRASGFPVFRDIQEGYQGPLAGMLAVMQQVASPWFVFCPCDTPFIPSFLVER
                     FIQQRGDAPVVWAHDGERDHPAVALVHRQIIPELEAYLAHGERRVMV"
     PFAM_domain     3642..3899
                     /aSDomain="DUF1040"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06288.15"
                     /description="Protein of unknown function (DUF1040)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_17_0003"
                     /evalue="4.00E-46"
                     /label="ctg1_17"
                     /locus_tag="ctg1_17"
                     /protein_end="86"
                     /protein_start="0"
                     /score="155.4"
                     /tool="antismash"
                     /translation="MKCKRLNEVIELLQPAWQKEPELNLMQFLQKLAKEAGYDGELSDL
                     SDDILIYHLKMRDSSKDAVIPGIQKDYEEDFKTALLRARGV"
     CDS             3642..3911
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MKCKRLNEVIELLQPAWQKEPELNLMQFLQKLAKEAGYDGELSDL
                     SDDILIYHLKMRDSSKDAVIPGIQKDYEEDFKTALLRARGVIKE"
     CDS             3987..4973
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_18"
                     /sec_met_domain="APH (E-value: 5.9e-44, bitscore: 149.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDKAFTFQTLRPDTIIDGLFDLGMRVDSGLTPLNSYENRVYQFQ
                     DEERHRYVVKFYRPERWSAEQILEEHQFALQLVEDEVPVAAPLLFNDSTLHQHQGFYFA
                     VFPSLGGRQFEADNLDQMEWVGRYLGRLHQTGCKQRFTARPEIGVQEYLLEPRQVFEQA
                     TLIPSGLKADFLKATDKLIAAVMEQWHGRGNTLRLHGDCHAGNILWRDGPLFVDLDDAR
                     TGPAIQDLWMLLNGDKAEQRMQLETIVEAYEEFSPFNSDEIALIEPLRAMRLVYYLAWL
                     LRRWDDPAFPVNFPWLTGEDYWRGQTSTFLEQVKVLQEPPLQLTPMY"
     PFAM_domain     4080..4748
                     /aSDomain="APH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01636.25"
                     /description="Phosphotransferase enzyme family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_18_0004"
                     /evalue="1.00E-44"
                     /label="ctg1_18"
                     /locus_tag="ctg1_18"
                     /protein_end="254"
                     /protein_start="31"
                     /score="153.3"
                     /tool="antismash"
                     /translation="TPLNSYENRVYQFQDEERHRYVVKFYRPERWSAEQILEEHQFALQ
                     LVEDEVPVAAPLLFNDSTLHQHQGFYFAVFPSLGGRQFEADNLDQMEWVGRYLGRLHQT
                     GCKQRFTARPEIGVQEYLLEPRQVFEQATLIPSGLKADFLKATDKLIAAVMEQWHGRGN
                     TLRLHGDCHAGNILWRDGPLFVDLDDARTGPAIQDLWMLLNGDKAEQRMQLETIVEAYE
                     E"
     CDS             5001..5624
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03651"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_19"
                     /sec_met_domain="TIGR03651 (E-value: 0.0004, bitscore:
                     18.8, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVWLALAGMILAFSASAAQITDGKQYITLDKPIAGEPQVLEFF
                     SFYCPHCYQFEEVLHVSDNVRQKLPEGTKMTKYHVEFLGPLGKDLTQAWAVAIALGVED
                     KITAPMFEAVQKNQTVQSVADIRKVFVDAGVKGEDYDAAWNSFVVKSLVAQQEKAAADL
                     QLQGVPAMYVNGKYQLNPQGMDTSNMDVFVAQYADTVKQLVEKK"
     PFAM_domain     5118..5588
                     /aSDomain="DSBA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01323.22"
                     /description="DSBA-like thioredoxin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_19_0005"
                     /evalue="5.80E-28"
                     /label="ctg1_19"
                     /locus_tag="ctg1_19"
                     /protein_end="196"
                     /protein_start="39"
                     /score="98.1"
                     /tool="antismash"
                     /translation="QVLEFFSFYCPHCYQFEEVLHVSDNVRQKLPEGTKMTKYHVEFLG
                     PLGKDLTQAWAVAIALGVEDKITAPMFEAVQKNQTVQSVADIRKVFVDAGVKGEDYDAA
                     WNSFVVKSLVAQQEKAAADLQLQGVPAMYVNGKYQLNPQGMDTSNMDVFVAQY"
     CDS             complement(5672..6571)
                     /locus_tag="ctg1_20"
                     /transl_table=11
                     /translation="MSRLLAAITLPLSIALTILVTIICSVPIIVAGLIKLLVPIPAVWR
                     SISVFCNFMMYCWCEGLALLLHLNPWLKWDVQGLEGLNKKNWYLLISNHHSWADIVVLC
                     VLFRKHIPMNKYFLKQQLAWVPFIGLACWALDMPFMRRYSRSYLIRHPERRGKDVETTR
                     RSCEKFRAHPTTIVNFVEGSRFTEEKKRETRSPYHNLLPPKAAGIAMALNVLGSQFDKL
                     LNVTLCYPDNHTRPFYDMLSGRLTRIVVRINLVPIGEELHGDYVNDKNFKRGFQRWLNG
                     LWEEKDRQLTDIMRDKER"
     PFAM_domain     complement(5939..6349)
                     /aSDomain="Acyltransferase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01553.23"
                     /description="Acyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_20_0006"
                     /evalue="1.30E-12"
                     /label="ctg1_20"
                     /locus_tag="ctg1_20"
                     /protein_end="211"
                     /protein_start="74"
                     /score="47.6"
                     /tool="antismash"
                     /translation="DVQGLEGLNKKNWYLLISNHHSWADIVVLCVLFRKHIPMNKYFLK
                     QQLAWVPFIGLACWALDMPFMRRYSRSYLIRHPERRGKDVETTRRSCEKFRAHPTTIVN
                     FVEGSRFTEEKKRETRSPYHNLLPPKAAGIAMA"
     CDS             6968..9760
                     /locus_tag="ctg1_21"
                     /transl_table=11
                     /translation="MVQIPENPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNM
                     LRSLILQYQPTHAVVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHKMVKAMGL
                     PLMAVPGVEADDVIGTLAREAERAGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPD
                     EVVTKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIA
                     ELSFRGAKTMAAKLEQNKDVAYLSYQLATIKTDVELELTCEELEVQPPAADDLLALFRQ
                     YEFKRWTTDVEAGKWLQAKGGKPAAKPAAPAAAAEAEEEVEAATALSAEHYVTILDEAT
                     LLTWIDKLKQAPLFAFDTETDSLDNISANMVGLSFAVEPGVAAYVPVAHDYLDAPDQIP
                     RERVLALLKPLLEDEKVLKVGQNLKYDRGILANYDIELRGIAFDTMLESYILDSVAGRH
                     DMDSLSDRWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPK
                     LQQHEGPLNIFQHIEMPLVPVLSRVERNGVKIDPAVLHAHSQEIAQRLVELEQRAHEIA
                     GEAFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGL
                     AKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQA
                     FIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAEVFGLPLDSVSS
                     EQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLEYMERTRAQAK
                     EQGYVETLDGRRLYLPDIKSSNGARRAGAERAAINAPMQGTAADIIKRAMIAVDEWLRS
                     EKPRVRMIMQVHDELVFEVHKDELDAVSKKIHELMENSTTLAVPLLVEVGSGENWDQAH
                     "
     PFAM_domain     6992..7477
                     /aSDomain="5_3_exonuc_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02739.18"
                     /description="5'-3' exonuclease, N-terminal resolvase-like
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_21_0007"
                     /evalue="7.90E-55"
                     /label="ctg1_21"
                     /locus_tag="ctg1_21"
                     /protein_end="170"
                     /protein_start="8"
                     /score="185.2"
                     /tool="antismash"
                     /translation="LILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLILQY
                     QPTHAVVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHKMVKAMGLPLMAVPGV
                     EADDVIGTLAREAERAGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPDEVVTKYG"
     aSDomain        6992..9757
                     /aSDomain="TIGR00593"
                     /aSTool="tigrfam"
                     /description="pola: DNA polymerase I"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_21_0003"
                     /evalue="6.80E-288"
                     /identifier="TIGR00593"
                     /label="ctg1_21"
                     /locus_tag="ctg1_21"
                     /protein_end="930"
                     /protein_start="8"
                     /score="955.8"
                     /tool="antismash"
                     /translation="LILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLILQY
                     QPTHAVVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHKMVKAMGLPLMAVPGV
                     EADDVIGTLAREAERAGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPDEVVTKYGV
                     PPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIAELSFRGAK
                     TMAAKLEQNKDVAYLSYQLATIKTDVELELTCEELEVQPPAADDLLALFRQYEFKRWTT
                     DVEAGKWLQAKGGKPAAKPAAPAAAAEAEEEVEAATALSAEHYVTILDEATLLTWIDKL
                     KQAPLFAFDTETDSLDNISANMVGLSFAVEPGVAAYVPVAHDYLDAPDQIPRERVLALL
                     KPLLEDEKVLKVGQNLKYDRGILANYDIELRGIAFDTMLESYILDSVAGRHDMDSLSDR
                     WLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPKLQQHEGPL
                     NIFQHIEMPLVPVLSRVERNGVKIDPAVLHAHSQEIAQRLVELEQRAHEIAGEAFNLSS
                     TKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYT
                     DKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYV
                     IVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAEVFGLPLDSVSSEQRRSAKA
                     INFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETL
                     DGRRLYLPDIKSSNGARRAGAERAAINAPMQGTAADIIKRAMIAVDEWLRSEKPRVRMI
                     MQVHDELVFEVHKDELDAVSKKIHELMENSTTLAVPLLVEVGSGENWDQAH"
     PFAM_domain     7478..7780
                     /aSDomain="5_3_exonuc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01367.22"
                     /description="5'-3' exonuclease, C-terminal SAM fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_21_0008"
                     /evalue="6.70E-31"
                     /label="ctg1_21"
                     /locus_tag="ctg1_21"
                     /protein_end="271"
                     /protein_start="170"
                     /score="106.9"
                     /tool="antismash"
                     /translation="VPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLY
                     AEPEKIAELSFRGAKTMAAKLEQNKDVAYLSYQLATIKTDVELELTCEELEVQPPA"
     PFAM_domain     7961..8524
                     /aSDomain="DNA_pol_A_exo1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01612.22"
                     /description="3'-5' exonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_21_0009"
                     /evalue="6.70E-42"
                     /label="ctg1_21"
                     /locus_tag="ctg1_21"
                     /protein_end="519"
                     /protein_start="331"
                     /score="143.3"
                     /tool="antismash"
                     /translation="YVTILDEATLLTWIDKLKQAPLFAFDTETDSLDNISANMVGLSFA
                     VEPGVAAYVPVAHDYLDAPDQIPRERVLALLKPLLEDEKVLKVGQNLKYDRGILANYDI
                     ELRGIAFDTMLESYILDSVAGRHDMDSLSDRWLKHKTITFEEIAGKGKNQLTFNQIALE
                     EAGRYAAEDADVTLQLHLKMWPKLQ"
     PFAM_domain     8627..9748
                     /aSDomain="DNA_pol_A"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00476.22"
                     /description="DNA polymerase family A"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_21_0010"
                     /evalue="2.30E-159"
                     /label="ctg1_21"
                     /locus_tag="ctg1_21"
                     /protein_end="927"
                     /protein_start="553"
                     /score="530.6"
                     /tool="antismash"
                     /translation="LHAHSQEIAQRLVELEQRAHEIAGEAFNLSSTKQLQTILFEKQGI
                     KPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRV
                     HTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIM
                     AHLSRDKGLLTAFAEGKDIHRATAAEVFGLPLDSVSSEQRRSAKAINFGLIYGMSAFGL
                     ARQLNIPRKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSN
                     GARRAGAERAAINAPMQGTAADIIKRAMIAVDEWLRSEKPRVRMIMQVHDELVFEVHKD
                     ELDAVSKKIHELMENSTTLAVPLLVEVGSGENWD"
ORIGIN
        1 tagcgcctcg tgaactcatc ttcgggggta gagcactgtt tcggctaggg ggtcatcccg
       61 acttaccaac ccgatgcaaa ctacgaatac cgaagaatgt tatcacggga gacacacggc
      121 gggtgctaac gtccgtcgtg aagagggaaa caacccagac cgccagctaa ggtcccaaag
      181 tcatggttaa gtgggaaacg atgtgggaag gcacagacag ccaggatgtt ggcttagaag
      241 cagccatcat ttaaagaaag cgtaatagct cactggtcga gtcggcctgc gcggaagatg
      301 taacggggct aaaccatgca ccgaagctgc ggcagcgaca ctatgtgttg ttgggtaggg
      361 gagcgttctg taagcctgcg aaggtgtgct gtgaggcatg ctggaggtat cagaagtgcg
      421 aatgctgaca taagtaacga taaagcgggt gaaaagcccg ctcgccggaa gaccaagggt
      481 tcctgtccaa cgttaatcgg ggcagggtga gtcgacccct aaggcgaggc cgaaaggcgt
      541 agtcgatggg aaacaggtta atattcctgt acttggtgtt actgcgaagg ggggacggag
      601 aaggctatgt tagccgggcg acggttgtcc cggtttaagc atgtaggctg attgtccagg
      661 caaatccgga taatcaaggc tgaggtgtga tgacgaggca ctacggtgct gaagtaacaa
      721 atgccctgct tccaggaaaa gcctctaagc atcaggtaac atcaaatcgt accccaaacc
      781 gacacaggtg gtcaggtaga gaataccaag gcgcttgaga gaactcgggt gaaggaacta
      841 ggcaaaatgg tgccgtaact tcgggagaag gcacgctggt gtgtaggtga agtccctgcg
      901 gatggagctg agaccagtcg aagataccag ctggctgcaa ctgtttatta aaaacacagc
      961 actgtgcaaa cacgaaagtg gacgtatacg gtgtgacgcc tgcccggtgc cggaaggtta
     1021 attgatgggg ttatccgtaa ggagaagctc ttgatcgaag ccccggtaaa cggcggccgt
     1081 aactataacg gtcctaaggt agcgaaattc cttgtcgggt aagttccgac ctgcacgaat
     1141 ggcgtaatga tggccaggct gtctccaccc gagactcagt gaaattgaac tcgctgtgaa
     1201 gatgcagtgt acccgcggca agacggaaag accccgtgaa cctttactat agcttgacac
     1261 tgaacattga gccttgatgt gtaggatagg tgggaggctt tgaagcgtgg acgccagtct
     1321 gcgtggagcc aaccttgaaa taccaccctt taatgtttga tgttctaacg ttggcccctg
     1381 accggggttg cggacagtgt ctggtgggta gtttgactgg ggcggtctcc tcccaaagcg
     1441 taacggagga gcacgaaggt tagctaatcc tggtcggaca tcaggaggtt agtgcaatgg
     1501 cataagctag cttgactgcg agcgtgacgg cgcgagcagg tgcgaaagca ggtcatagtg
     1561 atccggtggt tctgaatgga agggccatcg ctcaacggat aaaaggtact ccggggataa
     1621 caggctgata ccgcccaaga gttcatatcg acggcggtgt ttggcacctc gatgtcggct
     1681 catcacatcc tggggctgaa gtaggtccca agggtatggc tgttcgccat ttaaagtggt
     1741 acgcgagctg ggtttagaac gtcgtgagac agttcggtcc ctatctgccg tgggcgctgg
     1801 agaattgagg ggggctgctc ctagtacgag aggaccggag tggacgcatc actggtgttc
     1861 gggttgtcat gccaatggca ctgcccggta gctaaatgcg gaagagataa gtgctgaaag
     1921 catctaagca cgaaacttgc cccgagatga gttctccctg agactataag tctcctgaag
     1981 gaacgttaag acgatgacgt tgataggccg ggtgtgtaag cgcagcgatg cgttgagcta
     2041 accggtacta atgaaccgtg aggcttaacc ttacaacgcc gaagatgttt tggcggattt
     2101 gagaattttc agcttagatt cagagttgag tacgcaatat aaagaattgc atactgagca
     2161 caaagaattt gcctggcggc actagcgcgg tggtcccacc tgaccccatg ccgaactcag
     2221 aagtgaaacg ccgtagcgcc gatggtagtg tggggtctcc ccatgtgaga gtagggaact
     2281 gccaggcatc aaacaagtga agagcccatc ctgtcggatg ggctttttgc gtttctgtcg
     2341 tccggccagc gtgccggcat gtccccccgg tggcgctgcg cttgccgggg ctacggatcc
     2401 gacacggggc tacgtccctg tggccggaca aggtgcgcag caccgcctcc gggaaaatcc
     2461 ctcctatatc accgtcgata aatgactatt gcctctctaa ccaactcaca ataaatgtcg
     2521 cgatctgtgg tacatcattt aaatccagca gcggaagtga ggtcgcgatc gatacatcgc
     2581 tggccacggc gatggtatgc tcatcaatta ccagctcttc tacacgatgg ccgctgtttt
     2641 gccgaaaaag caggatcttc ggcacgggtt catgtttaaa cccctccact aaaaccaggt
     2701 ccagtttgct ggcatccatt cgactgacca gccacgtgag atctaattcc ggcttctctg
     2761 gcgtctcggt catcaatgcc caccgctgtt cgctggcgac aatagtttgc gcagcgcccg
     2821 ccttacgcag ttcatagcta tctttgcccg gcttatccac gtccatatca tgatgggtgt
     2881 gctttatcag tcccgggcgt aatcctagag cgcaaagctc agggataaga cgctttaata
     2941 atgttgtttt tccggtaccg ctccatgcgg cgatcgccag taatgggatc atgatggctc
     3001 ctgcatctgc tgcaaatctt cgagcgtatt tacattaatg aaagcagttt tcacatcgct
     3061 gaaattcacc gggcgcccac ccatttgtcg cataaaaacc atcaccctgc gctctccatg
     3121 tgccagataa gcctccagtt caggaatgat ttgacgatga actaatgcaa cggcaggatg
     3181 atcccgttcg ccgtcatggg cccaaacgac cggtgcgtcc cctctctgct ggataaagcg
     3241 ctccaccaaa aaggacggaa tgaacggcgt gtcgcagggg caaaaaacaa accatgggct
     3301 cgcgacctgc tgcatcacag caagcattcc ggccagcggt ccctgataac cctcctgtat
     3361 gtctcgaaag accggaaatc cgctggcacg ccactgttca agatgacgat tggcgctaat
     3421 gactaactca tctacctgcg gggctaatgc ttccgcgacg tgtcgccaga gagggcgacc
     3481 atttagcgcc tgtaatcctt tatcaatgcc gcccatccgc gtggccctgc cgcccgccag
     3541 cacgacgccg gttatcgcct cgctttgcat atgaatatcg cctctttcat tgtgggattg
     3601 accctgttaa cttgtcccta tcaagagtaa ggagcatgac catgaaatgt aaacgtctga
     3661 atgaagtaat tgaactcctc cagccagcct ggcaaaaaga gcctgaactg aacctgatgc
     3721 aatttttgca gaagctggcg aaagaggccg gctatgatgg cgaactgagc gatctttccg
     3781 acgatattct gatctatcac ctgaagatgc gcgactcttc caaagatgct gtcatcccgg
     3841 gtattcagaa ggattatgaa gaggacttta aaaccgcgct gctgcgcgcc cgcggggtaa
     3901 taaaagagta aaaggttgta agcgctaccg cgtaaagtgc aatgagatga tatcctgaac
     3961 tattcgtacg attatcggat gtcaggatgc acgataaggc ttttactttt cagacgcttc
     4021 gcccggatac cattatcgat gggttattcg atctgggtat gcgggtggac tccggtctca
     4081 ccccgctaaa cagctatgag aaccgcgttt atcagttcca ggacgaagag cgccatcgct
     4141 atgtggtaaa gttctatcgt cctgagcgct ggtccgcaga acagatcctt gaagaacacc
     4201 agtttgcgct tcagcttgta gaagatgaag tgcccgttgc tgcgccgctc ttatttaatg
     4261 acagcacgct tcatcagcat cagggattct actttgccgt tttcccaagc cttggcggtc
     4321 gtcagttcga agcggataac cttgatcaga tggaatgggt tggccgctat ctggggcgcc
     4381 tgcaccagac gggctgcaaa cagcgcttta ctgcccgccc ggaaattggc gtgcaggagt
     4441 acctgctgga accgcgtcag gtgtttgagc aggcgacgct gatcccctct ggcctgaagg
     4501 ccgatttcct gaaggcgacc gataaactca ttgctgccgt catggagcaa tggcacggcc
     4561 gcgggaacac gttgcgcctg cacggtgact gccatgccgg taatatcctc tggcgcgacg
     4621 gaccactgtt tgtcgactta gacgatgcgc gcaccggccc ggcgattcag gatctgtgga
     4681 tgctgctcaa cggcgataag gctgaacagc gtatgcagct ggagactatt gtcgaggcct
     4741 atgaggaatt cagccccttt aacagcgatg aaatcgcgct gattgaacct ttacgcgcta
     4801 tgcgactggt ttattatctg gcgtggttgc tcagacgctg ggacgatccc gctttcccgg
     4861 tcaatttccc ctggttaacc ggggaggatt actggcgggg gcagacgtcg acttttcttg
     4921 agcaggtgaa ggttctacag gaacccccgc ttcagttaac gccaatgtat taatgtgata
     4981 tatccaggag agagtaaatc atgaaaaaag tttggctggc gctggctggt atgattctgg
     5041 cttttagtgc atccgctgcc cagatcaccg acggcaagca gtacatcacc cttgataagc
     5101 cgattgctgg cgagccgcag gtgctcgagt tcttttcgtt ctactgcccg cactgctacc
     5161 agtttgaaga agtgctgcat gtctctgaca atgtgcgcca gaaactgccg gaaggcacta
     5221 aaatgaccaa ataccacgtt gagttcctgg gtccgctggg caaggatctg acgcaggcat
     5281 gggcggtggc catcgcgctg ggcgttgaag acaaaattac tgcgccgatg ttcgaagccg
     5341 tgcagaaaaa ccagactgtg cagagtgtgg ctgacattcg taaagtgttt gtcgacgctg
     5401 gcgtgaaagg ggaagactac gatgccgcat ggaatagctt cgtggtgaaa tctctggtcg
     5461 ctcagcaaga gaaagcggca gccgatctgc agctgcaggg cgtaccggct atgtatgtta
     5521 atggtaaata ccagctgaat ccgcagggga tggacaccag caatatggat gtcttcgtcg
     5581 ctcagtatgc ggataccgtg aagcaactgg tagagaagaa ataaaaaaac gccggtcact
     5641 gaccggcgtt actttatctg ttttgcaata gctaccgttc tttgtccctc atgatgtcag
     5701 tcaactgacg gtctttctct tcccataggc cattcagcca gcgctggaag ccgcgcttaa
     5761 agttcttatc gttaacgtaa tcgccgtgca gctcttcgcc aatagggacc agattgatac
     5821 ggaccacgat gcgcgtcagg cggccgctta acatatcgta aaatggtctt gtatgattat
     5881 ccgggtagca cagcgtgacg ttcagcagtt tatcgaactg cgaaccgagt acgttgagcg
     5941 ccatggcgat accagcggct ttcggcggta acaggttgtg gtaaggagag cgcgtttcgc
     6001 gctttttttc ttcggtaaaa cgcgagcctt ccacaaaatt gacgatagtc gtcggatgcg
     6061 cgcgaaattt ttcacacgaa cggcgggtgg tttcgacatc tttaccgcgg cgctccgggt
     6121 gacgaataag atagctgcgc gagtagcggc gcataaaagg catatccagc gcccagcagg
     6181 cgaggccaat gaagggtacc cacgccagct gttgtttaag gaagtactta ttcatcggaa
     6241 tatgcttgcg gaacagcacg cacagcacca cgatgtctgc ccagctgtgg tggttgctga
     6301 tcagcagata ccagttcttt ttgttcaggc cttccagacc ctggacgtcc cattttagcc
     6361 agggattgag atgcaacagc agcgccagcc cttcgcacca gcagtacatc ataaaattgc
     6421 aaaaaacgga tatagagcgc cataccgctg gaatggggac cagcagttta atcagcccgg
     6481 cgacgatgat cggtacagag cagataatgg tgactaagat ggttaaggcg atactcagcg
     6541 gaagtgttat cgcagcgagt aatctcgaca tagttagttt attcagaaag ttaggctgac
     6601 aaagagcgcc tttaagctgc gcaagaggct gattttacca gaaaacgcgg caaatgacgg
     6661 gtcttaccag aacagaaaaa aacaaggatc ttctatccac atggaagatt aggtcatcaa
     6721 attaatgcca ggatcgttga tttgttttta agtggttgat aaatagtaaa taatactatt
     6781 tattcattta ttttcagggg cggataagct gacgttgtaa aactatacac aaagttatcc
     6841 acaagctaag ttgtcgcgcg atcgcgacga tcgttgaatc ttttccgcga attgcgggaa
     6901 aaattcagga tttcatgccc gtctgtggca tcctttatcc ataatctgat aaacaggcac
     6961 ggaaattatg gttcagatcc cagaaaaccc tctcatcctc gttgatggct cctcctatct
     7021 ttatcgggcg tatcatgcgt ttccgccgct gactaacagc gcaggggagc ccaccggggc
     7081 tatgtacggc gtactgaata tgctgcgcag tttgatactg cagtatcaac cgactcatgc
     7141 cgtcgtggtc tttgatgcga aagggaaaac cttccgtgat gaattgttcg agcattacaa
     7201 atctcaccgc ccgccgatgc cggacgatct gcgcgcgcag attgagccgt tgcataagat
     7261 ggtgaaagcg atggggctgc cgctgatggc agtcccgggc gtcgaagctg acgatgtgat
     7321 tggcaccctg gcgcgggaag cggaaagggc aggtcgccca gtcctgatca gcaccggcga
     7381 taaagacatg gcccagctgg tgacgccggg catcaccctg atcaatacca tgaccaacac
     7441 tatcctcgga ccggatgagg tggttactaa gtacggcgtc ccgccggagc tgattattga
     7501 tttcctggcg ctgatgggcg actcctcgga taacattccc ggcgtgccgg gcgtgggcga
     7561 aaagaccgcc caggcgctgc tgcaaggcct cggcggcctt gatacgctgt atgcggaacc
     7621 ggagaagatc gctgaactga gcttccgcgg cgcgaaaacg atggcggcga agctcgagca
     7681 gaacaaggac gtggcttatc tctcttatca gctggcgacc atcaaaaccg acgtcgagct
     7741 ggagctcacc tgcgaagagc tggaggtgca gccgccggcg gcagacgatc tgctggcgct
     7801 gttcagacag tatgaattta agcgctggac caccgacgtt gaggccggaa aatggctgca
     7861 ggctaagggg ggcaaaccgg ctgcgaaacc tgcagcgcct gcagcagcgg cagaagcgga
     7921 agaagaggtt gaagccgcta ctgcactttc agcagagcat tatgtcacta tccttgatga
     7981 ggctacgctg ctcacctgga tcgataagct gaagcaggcg ccgctctttg cctttgatac
     8041 ggaaaccgac agcctggata acatctccgc caacatggtt ggtctttcat tcgctgttga
     8101 gccaggcgtg gccgcctatg tcccggtagc gcatgattat cttgatgcgc cggatcagat
     8161 cccgcgcgag cgcgtgctgg cgctgcttaa accgctgctg gaggatgaga aggtgctcaa
     8221 ggtcgggcaa aatctcaaat acgatcgcgg cattttggct aattacgaca ttgagctgcg
     8281 cgggattgcg ttcgatacca tgctcgagtc ttacattctc gacagcgtgg cgggccgcca
     8341 cgatatggac agtctttccg accgctggct gaaacataaa accattacct tcgaagagat
     8401 cgctggcaag ggtaagaatc agctcacctt taaccagatt gcgctggaag aggctggtcg
     8461 ctacgcggcg gaagatgccg acgttacgct ccagctgcat ctgaagatgt ggccgaagct
     8521 acagcagcat gaaggcccgc tgaatatctt ccagcatatt gaaatgccgc tggtgccggt
     8581 gctgtctcgc gttgagcgca acggcgttaa aatcgacccc gccgtgctgc atgcgcactc
     8641 gcaggaaatt gcccagcgcc tggttgagct ggagcagcga gcacatgaga tcgccgggga
     8701 agcgtttaat ctctcctcca ccaaacagct gcaaacgatc ctgtttgaaa aacagggtat
     8761 caagccgctg aagaagacgc cgggcggtgc gccgtccacc tctgaagagg tgctggaaga
     8821 gctggcgctc gattatccgt tgccgaaagt gattctggag tatcgtgggc tggcgaagct
     8881 gaagtcgacc tataccgata agctgccgct gatgattaac cccaaaacgg gccgcgtgca
     8941 tacctcctat catcaggcgg tcaccgccac cggccgtttg tcgtctaccg atccaaacct
     9001 gcaaaacatt ccggtgcgta acgaagaagg gcgccgtatt cgccaggcgt ttatcgcgcc
     9061 ggaagattac gtcattgtct cggcggacta ctcgcaaatc gagctgcgca ttatggcgca
     9121 cctgtcgcgg gataaaggcc tgctgaccgc cttcgcggaa gggaaggata ttcaccgggc
     9181 gacggcggct gaagtatttg gcttaccgct ggacagcgtc agcagcgaac agcggcgcag
     9241 tgcgaaagcc atcaacttcg gtctgatcta cggcatgagc gcctttggcc tggcccgcca
     9301 gctgaacatc ccgcgtaaag aagcgcagaa gtacatggat ctttatttcg aacgttatcc
     9361 gggcgtcctg gagtatatgg agcgcacccg cgcacaggcg aaggagcaag ggtatgttga
     9421 aacgctggat ggccgtcgac tctatttgcc ggatatcaag tccagcaatg gcgctcgtcg
     9481 tgccggcgcg gagcgtgcgg cgattaacgc cccgatgcag gggacggctg cggatattat
     9541 caagcgggcg atgattgccg ttgatgaatg gctgcggagc gagaaacctc gcgtgcggat
     9601 gatcatgcag gttcacgatg aactggtctt tgaagtgcat aaggatgagc tcgatgccgt
     9661 atcgaaaaag atccacgaac tgatggagaa cagcactacg ctggcggtac cgttgctggt
     9721 ggaagtgggc agcggcgaaa actgggatca agcgcactaa gtatacaaag cgcaacgcga
     9781 ttttctgtaa gtaagcaaca taacttatag agttttgtga ggatcatttg aatttgctat
     9841 gtaaatagtg aaaaaaaact acaaaaaatg ctttatccgt gagcgaaaga agagtaaagt
     9901 tattcgcgta gggtacagag gtaagatgtt ctatctttca gaccttttac ttcacgtaat
     9961 cggatttggc tgaatatttt agccgccccg gtcatttatg accggggcgt tttttattgc
    10021 gcgaaagaaa agtttaaggc tgtgaaaaca acgtagtatg aacgtccgga tagggcgcta
    10081 cgcgccgtta tccggaaaaa gcgggggtta ctcggcgtct tcgacggctt cttgcggcgg
    10141 gatttcgtta aaccagctat ccagcttctg tcgcagctta tcgacgccag attttttcag
    10201 cgaagagaag ggttcaacct ggacatcgcc attgaaggcc agtaccgctt cacgcaccat
    10261 attcacttgc gctttacgcg cgccgctggc gagcttatcg gctttggtga gcagtaccag
    10321 cacctgaata tcgctctcta ccgcccattc gatcatctgc tgatcgagat ctttaagcgg
    10381 atgacgtatg tccatcagca ccacgagacc cttcaggcat agacgttttt ccaggtattc
    10441 ccccagcgcg cgctgccact tgatcttcat ctcttcgggt acttgcgcat aaccatagcc
    10501 gggcaggtcg acaaggcgct tgccctcagc gacttcgaac aggttaatca gctgcgtacg
    10561 ccccggggtt ttggaggtac gcgccaggtt cttctgatta gtcagcgtat tcagcgcgct
    10621 ggat
//
