LOCUS       c00011_NZ_JACH..       10707 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JACHBK010000011.1 Rhizobium giardinii strain SEMIA 4084
            Ga0394389_11, whole genome shotgun sequence.
ACCESSION   c00011_NZ_JACH..
VERSION     c00011_NZ_JACH..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:49:12
            Original ID  :: NZ_JACHBK010000011.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10707
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..519
                     /locus_tag="ctg11_1"
                     /transl_table=11
                     /translation="RARIVSQVVLLEYRPKRVTAVTQREYFGSSRLRSADATLTVRSDS
                     FRQRPHYLVSLYPEGNGGPGGRQAAPLFVSLDGSSCDGESTGSASITVLTDRGSLGPAN
                     VLNGRARNVRACHHNKPTAEKRRCDQTFVRIWIAASRHCLRGLRNQARMCDLDSFTGSC
                     PKGRLPWRR"
     protocluster    1..10707
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4819:5707](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(4820..5707)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10707
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10707
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(476..820)
                     /locus_tag="ctg11_2"
                     /transl_table=11
                     /translation="MPENANKSPAVESLKQERARQRERTAKGELDKGLEHTFPASDPVS
                     MTTTSIPSGRTDADKAEQVRVNPDPTALGPEIAEEAPTLLADIRNIVRERPLAAVAIVA
                     TVAYLLGTSR"
     CDS             complement(1101..1220)
                     /locus_tag="ctg11_3"
                     /transl_table=11
                     /translation="MLVAFGAQPMGETAATGITHYIGDYPVGQVRTYEGFAWR"
     CDS             1342..3243
                     /locus_tag="ctg11_4"
                     /transl_table=11
                     /translation="LTPDPVSNDGESHLADNTNFRVLVLGAIGVVYGDIGTSPIYAFRE
                     ALHASRQSAGGTVTEVLGLLSLIVWALTIVVTVKYVGFVLKADNKGEGGTLSLMTLARN
                     SLTGRSAWVLVLGIIGASLFLGDAIITPAISVLSAVEGLEVLAPQLANWVVPTTLCIII
                     ALFFVQRFGTGRVASVFGPITALWFLALGVSGLVHIFEAPGVLVALNPYYGVRFLIDHL
                     HIAVSVLGAVFLAVTGAEALYVDLGHFGRRPIVFAWFALVFPCLLLNYFGQGAFVLTHL
                     ASVEHPFFEMQPDWALLPMVALATMATVIASQAVISGAFSLMSQAMHLNLLPRFTVLHT
                     SETRVGQIFMPQVNFLLLVSVVLLVIGFKSSSALSAAYGIAVTGEMLVTSVLLIVVMRQ
                     IWRWRLMAALAVIIPIFIIDAGFLAANVAKFAQGGWVPAVVAIFIAFLMQTWISGRKLL
                     SDRTKADDVPLNFLLENLTKKKPNTVPGTAIFLTSEVEGAPTALLHSLKHYKVLHEHNV
                     ILSVVTSSSPVVPDDEKVHFESFNPLFSRAVITFGYMETPNIPKALALARKLGWKFDIM
                     STSFFLSRRTIKPSVKGGMPLWQDRVFIALARNASNATEYFQLPTGRVVELGIQVTI"
     PFAM_domain     1414..3006
                     /aSDomain="K_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02705.18"
                     /description="K+ potassium transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_4_0001"
                     /evalue="3.30E-198"
                     /label="ctg11_4"
                     /locus_tag="ctg11_4"
                     /protein_end="555"
                     /protein_start="24"
                     /score="659.6"
                     /tool="antismash"
                     /translation="LGAIGVVYGDIGTSPIYAFREALHASRQSAGGTVTEVLGLLSLIV
                     WALTIVVTVKYVGFVLKADNKGEGGTLSLMTLARNSLTGRSAWVLVLGIIGASLFLGDA
                     IITPAISVLSAVEGLEVLAPQLANWVVPTTLCIIIALFFVQRFGTGRVASVFGPITALW
                     FLALGVSGLVHIFEAPGVLVALNPYYGVRFLIDHLHIAVSVLGAVFLAVTGAEALYVDL
                     GHFGRRPIVFAWFALVFPCLLLNYFGQGAFVLTHLASVEHPFFEMQPDWALLPMVALAT
                     MATVIASQAVISGAFSLMSQAMHLNLLPRFTVLHTSETRVGQIFMPQVNFLLLVSVVLL
                     VIGFKSSSALSAAYGIAVTGEMLVTSVLLIVVMRQIWRWRLMAALAVIIPIFIIDAGFL
                     AANVAKFAQGGWVPAVVAIFIAFLMQTWISGRKLLSDRTKADDVPLNFLLENLTKKKPN
                     TVPGTAIFLTSEVEGAPTALLHSLKHYKVLHEHNVILSVVTSSSPVVPDDEKVHFESFN
                     PLFSRAVITFGYME"
     CDS             complement(3228..3344)
                     /locus_tag="ctg11_5"
                     /transl_table=11
                     /translation="MYWRRLCLALRHRLRSQAGYRRSLRLDLKSNELNHIVT"
     CDS             complement(3547..4044)
                     /locus_tag="ctg11_6"
                     /transl_table=11
                     /translation="MKTEAAPSHGSGAVLAALIIRTEGLLASVPPSLPLLALRFALAIP
                     FFKSGLTKWDGFLTLSPGARFLFEQEFKLHVFGSEIPYPFPLAMAAAAGIAELVLPILL
                     ILGFATRFASLGLLLMTAIIQLTVPDGWANFHLPWAAMALALVVFGGGRIALDPFVMPR
                     RK"
     PFAM_domain     complement(3661..3942)
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_6_0002"
                     /evalue="1.70E-17"
                     /label="ctg11_6"
                     /locus_tag="ctg11_6"
                     /protein_end="128"
                     /protein_start="34"
                     /score="63.9"
                     /tool="antismash"
                     /translation="LLALRFALAIPFFKSGLTKWDGFLTLSPGARFLFEQEFKLHVFGS
                     EIPYPFPLAMAAAAGIAELVLPILLILGFATRFASLGLLLMTAIIQLTV"
     CDS             complement(4041..4823)
                     /locus_tag="ctg11_7"
                     /transl_table=11
                     /translation="MTMDLAASQTAFADALLHADRPVPDGITTARGEVDAARFAVYRNN
                     VFVGLSKALAQRFPVTERLVGTEFFMAMARAYAQDHKPASPLIIEYGDDFPDFIASFQP
                     ASKLAYLPDVARIEAAWTRSYYAADAVPIKLAVLAAVAPEMLADLRLVPHPSAALIRSE
                     YPIGSIWSAHHEEMVTPVADWRPQVVLVARPEMTVEVHILPPQDVIFATSLFNHATLGA
                     AAGAAFAAGPAFNFGAALMGLVCLGAFSALQQDEGNVP"
     PFAM_domain     complement(4527..4799)
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_7_0003"
                     /evalue="4.80E-26"
                     /label="ctg11_7"
                     /locus_tag="ctg11_7"
                     /protein_end="99"
                     /protein_start="8"
                     /score="90.9"
                     /tool="antismash"
                     /translation="QTAFADALLHADRPVPDGITTARGEVDAARFAVYRNNVFVGLSKA
                     LAQRFPVTERLVGTEFFMAMARAYAQDHKPASPLIIEYGDDFPDFI"
     CDS             complement(4820..5707)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_8"
                     /sec_met_domain="DUF692 (E-value: 8.1e-91, bitscore: 297.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASKTQADALPARAGLGLKPQHYDAILADRPDVGFFEVHAENYM
                     GAGGPPHHYLEAITQFYPLSLHGVGLSIGAARGLDKEHLKRLRDLIDRYRPHSFSEHLA
                     WSTHDTGFLNDLLPLPYTAETLARVIDHIDATQQTLGRRLLLENPSTYVLFADSTIDEV
                     DFLATIAERTACGLLLDVNNVMVSAVNHRLDAATYIDRFPVELVGEIHLAGYDETVDDA
                     GERLLIDAHGTAVKSDVVALYEHTLARSGPLPTLIEWDNDVPDFATLLAEAARADAMLA
                     SEALRRTRRRIRAA"
     PFAM_domain     complement(4868..5665)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_8_0004"
                     /evalue="1.20E-102"
                     /label="ctg11_8"
                     /locus_tag="ctg11_8"
                     /protein_end="280"
                     /protein_start="14"
                     /score="342.8"
                     /tool="antismash"
                     /translation="AGLGLKPQHYDAILADRPDVGFFEVHAENYMGAGGPPHHYLEAIT
                     QFYPLSLHGVGLSIGAARGLDKEHLKRLRDLIDRYRPHSFSEHLAWSTHDTGFLNDLLP
                     LPYTAETLARVIDHIDATQQTLGRRLLLENPSTYVLFADSTIDEVDFLATIAERTACGL
                     LLDVNNVMVSAVNHRLDAATYIDRFPVELVGEIHLAGYDETVDDAGERLLIDAHGTAVK
                     SDVVALYEHTLARSGPLPTLIEWDNDVPDFATLLAEAARADAML"
     CDS             complement(5769..6056)
                     /locus_tag="ctg11_9"
                     /transl_table=11
                     /translation="MNRSTLTLTLAGSLAAALASVAFAAPLPAEKMVGNEKCYGIALKG
                     QNDCAAGAGTTCAGTSTMDYQGNAWKAVPAGTCTSMNVDGHMGKLEPIKG"
     PFAM_domain     complement(5802..5954)
                     /aSDomain="DUF2282"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10048.11"
                     /description="Predicted integral membrane protein
                     (DUF2282)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_9_0005"
                     /evalue="1.10E-25"
                     /label="ctg11_9"
                     /locus_tag="ctg11_9"
                     /protein_end="85"
                     /protein_start="34"
                     /score="89.5"
                     /tool="antismash"
                     /translation="NEKCYGIALKGQNDCAAGAGTTCAGTSTMDYQGNAWKAVPAGTCT
                     SMNVDG"
     CDS             6245..6778
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 100.7;
                     E-value: 1.2e-30)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg11_10"
                     /transl_table=11
                     /translation="LNGDAENELATLLRAAIAGDERAYAEFLGRTAAIVRGFARRKIQG
                     GVDPEDIVQETLLALHMKRHTWKTDAPVSPWVYAIARFKLIDAFRKRGRHVEVEIGEIA
                     ETVAQPEAETVSDREIGRVLDGLTAGQRSVVAAISIEGRSIGETAAKFGMTETAVRVAL
                     HRGLRSIAKKFGRS"
     aSDomain        6311..6763
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg11_10_0001"
                     /evalue="1.70E-17"
                     /identifier="TIGR02937"
                     /label="ctg11_10"
                     /locus_tag="ctg11_10"
                     /protein_end="173"
                     /protein_start="22"
                     /score="61.5"
                     /tool="antismash"
                     /translation="AYAEFLGRTAAIVRGFARRKIQGGVDPEDIVQETLLALHMKRHTW
                     KTDAPVSPWVYAIARFKLIDAFRKRGRHVEVEIGEIAETVAQPEAETVSDREIGRVLDG
                     LTAGQRSVVAAISIEGRSIGETAAKFGMTETAVRVALHRGLRSIAKK"
     PFAM_domain     6341..6526
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_10_0006"
                     /evalue="1.70E-11"
                     /label="ctg11_10"
                     /locus_tag="ctg11_10"
                     /protein_end="94"
                     /protein_start="32"
                     /score="43.8"
                     /tool="antismash"
                     /translation="AIVRGFARRKIQGGVDPEDIVQETLLALHMKRHTWKTDAPVSPWV
                     YAIARFKLIDAFRKRGR"
     PFAM_domain     6596..6748
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_10_0007"
                     /evalue="3.70E-10"
                     /label="ctg11_10"
                     /locus_tag="ctg11_10"
                     /protein_end="168"
                     /protein_start="117"
                     /score="39.4"
                     /tool="antismash"
                     /translation="REIGRVLDGLTAGQRSVVAAISIEGRSIGETAAKFGMTETAVRVA
                     LHRGLR"
     CDS             6780..7418
                     /locus_tag="ctg11_11"
                     /transl_table=11
                     /translation="MQTNDLINALRADAAKQAMPLGYSWWIAIVAATIIAAGAFFILIG
                     PRPDFTVAAHTPRFLFKFIVTLALVVVAFALLRVLSRPGSDVRHVAYWLVLMPILLGTA
                     VAAELFAVPSDQLVTVWWGSNVYVCLTFIPLIGLGALAVFLAALRHGAPTRPRLAGAVA
                     GLLAGGIAATFYAAHCTDDSPLFVATWYSIAIAGLVALGAICGRRVARW"
     PFAM_domain     6822..7415
                     /aSDomain="NrsF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06532.13"
                     /description="Negative regulator of sigma F"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_11_0008"
                     /evalue="6.60E-57"
                     /label="ctg11_11"
                     /locus_tag="ctg11_11"
                     /protein_end="212"
                     /protein_start="14"
                     /score="192.7"
                     /tool="antismash"
                     /translation="AKQAMPLGYSWWIAIVAATIIAAGAFFILIGPRPDFTVAAHTPRF
                     LFKFIVTLALVVVAFALLRVLSRPGSDVRHVAYWLVLMPILLGTAVAAELFAVPSDQLV
                     TVWWGSNVYVCLTFIPLIGLGALAVFLAALRHGAPTRPRLAGAVAGLLAGGIAATFYAA
                     HCTDDSPLFVATWYSIAIAGLVALGAICGRRVARW"
     CDS             7685..7978
                     /locus_tag="ctg11_12"
                     /transl_table=11
                     /translation="MLAGSPVDRAPYNVPSHILERGIPSGKLRSSTTHMQTRTRVYIAN
                     VSPMGHEGWDTLPPEVLKAVHAKIGPIATPDKTKFAPGLLKSPRKIKRRILR"
     CDS             8220..8459
                     /locus_tag="ctg11_13"
                     /transl_table=11
                     /translation="MNDVQQLHVYYDYRSKTVLVEFADRSHVLAERFEDNESAQQGAIR
                     YAVMQWGYRMPDSQKEGPAMAFDQRMRDGSQSAG"
     CDS             complement(8546..8797)
                     /locus_tag="ctg11_14"
                     /transl_table=11
                     /translation="VKIGYEERIAHLLHGGADAMLVPSGSGGLSETVIDANDAALHARA
                     ATGIQFSPIDADGLRQPSGALSRCFATIMPLTNCGGRQ"
     CDS             9415..9552
                     /locus_tag="ctg11_15"
                     /transl_table=11
                     /translation="MGVHDALAAGRSAMSLPDVARETFLAAALEVRCRVKSSTDSGTDS
                     "
ORIGIN
        1 cgtgcgagga ttgtgagcca agttgtgctg cttgaatatc gccccaaacg ggtaaccgct
       61 gtaactcaaa gggagtattt cggcagcagc aggctcagat ccgcagatgc cactcttaca
      121 gttcggtctg atagctttcg tcaacgtccg cattaccttg tttcattgta tcccgaaggg
      181 aacggaggtc cgggcggccg gcaggcagct ccgttgttcg tgtcactgga cggaagcagt
      241 tgtgatggag aatctaccgg aagtgcatcc atcactgttt tgacggatag gggatcactc
      301 ggccctgcga atgtgctcaa cggtcgagcg agaaatgtca gggcttgcca ccacaacaag
      361 ccgaccgcgg agaaacgcag gtgcgaccag acgttcgtca gaatctggat cgccgcatcg
      421 cgacactgtc tgagaggact caggaaccag gcgcggatgt gcgatctcga ctcgttcacc
      481 ggctcgtgcc caaaaggtag gctaccgtgg cgacgatagc tacggcggcc aatggccgct
      541 ccctgacaat attcctgata tcggcaagga gagtcggcgc ttcttcggcg atttcaggcc
      601 cgagtgctgt cggatccgga ttgaccctga cctgttccgc cttgtccgcg tcagtacggc
      661 cggacgggat gctggtagtg gtcatcgaca cggggtcaga agccgggaac gtatgttcca
      721 accccttgtc gagttcgccc tttgcggtgc gttctcgctg ccttgcccgc tcttgcttca
      781 aggattccac ggctggcgac ttgtttgcgt tctctggcat gagcttgtcc tccaatggaa
      841 tttaataatt ccatcaggcg atcgaagttc ccctcggatg gctttgattg ttcggagggc
      901 gagcaatcgg aataagggga tagcgttacg gcatcggtta ctggcagtga acaagccgcc
      961 gatttacatg gatgccaaaa tgacgatctt ctttgcccaa tgcgttgatg tgaggaatgc
     1021 cgcaccggtg aactgccgaa gtcaacgcgc tccgacgtag caagaaaata agtcgcctgg
     1081 ccacatgagc tcgacgggga ttacctccat gcgaagcctt cgtacgtccg gacctgacca
     1141 acgggataat ccccgatata atgcgttatc ccggtcgccg ctgtttcgcc cattggttgt
     1201 gcgccgaaag ccacaagcat aataagtgat cccacaagac cgaggaggca tagctgaccc
     1261 gccgtcgagc tccaacgagt ggcaggttga accgtagcct gtctagctat aaagcttgat
     1321 gtctaaatcc ggagaccgag attgacgcct gatccagtgt cgaacgatgg cgagagccac
     1381 ctagcggaca acaccaactt ccgcgtcctg gttctggggg caatcggagt tgtgtatggc
     1441 gatatcggta ccagtcctat ctatgcgttc cgtgaggcgc ttcatgcatc caggcagtcg
     1501 gccggcggaa ccgtcacgga agttctcggg cttctttccc ttatcgtctg ggcgctgacc
     1561 attgttgtca cggtcaaata tgtcggcttc gttttgaagg cagacaacaa aggagaagga
     1621 gggacgcttt ccttgatgac gcttgcccgg aacagcctga ccggccgatc tgcctgggtt
     1681 ttggttctcg gcatcatcgg tgcgtcgttg tttcttggtg atgccatcat cactccggcg
     1741 atttccgttc tctcagccgt tgaaggactg gaagtccttg caccgcagct cgccaattgg
     1801 gtcgtgccga caacgctgtg catcatcatc gctcttttct tcgttcagag atttgggacc
     1861 ggtcgcgttg catctgtctt tggtccgatc accgcgctgt ggtttctggc acttggcgtc
     1921 tcgggcctcg tccatatctt cgaagcgcca ggcgttttgg tggctctcaa tccatactac
     1981 ggtgtccgct tcctgatcga ccatttgcat atagccgttt ccgtgctcgg tgcggtcttt
     2041 ctggccgtca cgggtgcgga ggccctctat gttgatctcg ggcatttcgg ccgccgcccg
     2101 atcgtcttcg cctggtttgc gctggtgttt ccatgccttc tgttgaacta tttcgggcag
     2161 ggggctttcg tgctgaccca tctcgcgtcc gtcgagcatc ccttcttcga gatgcagccc
     2221 gattgggcgc tgctgccgat ggtggcgttg gccacgatgg cgaccgtcat tgccagccag
     2281 gccgttattt caggtgcatt ttcgctcatg agccaggcga tgcacctcaa cctgctaccc
     2341 cgtttcacag tgctccacac ctccgaaaca cgggtggggc agatttttat gccgcaggtc
     2401 aatttcctac tgctggtctc ggtcgtcctt ctggtgatag gcttcaaaag ttcaagcgcc
     2461 ctttccgcgg cctacggtat cgcagtgaca ggggagatgt tggtgacatc tgttctgctt
     2521 atcgtcgtga tgcggcagat atggcgttgg cgactcatgg ccgcactcgc ggtgatcatc
     2581 cccattttca tcatcgacgc cgggttcctt gccgccaatg tcgcgaaatt cgcccagggg
     2641 ggctgggtgc cagcagttgt cgccatcttc atcgccttcc tgatgcagac atggatatcg
     2701 ggacgcaagc tgctgtcaga cagaaccaaa gccgatgacg tgccgctgaa tttccttctc
     2761 gagaatctga cgaagaagaa gcccaacact gttcccggaa cggcgatctt tctgaccagc
     2821 gaagttgagg gcgcgccaac cgctctcctt cacagtctta aacactacaa agtcctgcac
     2881 gaacacaacg taattctgag cgtggttaca tccagctcgc cagtcgtgcc cgacgacgag
     2941 aaagtccact ttgagagctt caatccgttg ttcagccgcg ccgtcatcac cttcggttat
     3001 atggagacgc ccaacatccc gaaggctctc gcactggcac gaaaactcgg ctggaagttc
     3061 gatatcatgt cgacgtcgtt ctttttgtcg cgccgtacga tcaagccatc ggtgaagggc
     3121 ggaatgccgc tttggcagga tcgcgtgttc attgcccttg cccggaatgc cagcaacgcc
     3181 acggaatact ttcaacttcc gacgggccgt gtggtcgagc tcggaattca ggtcacgata
     3241 tgattcagct cgttcgactt aaggtccaag cgaaggctac ggcgatagcc ggcctgggaa
     3301 cgaagacgat ggcgtaaagc caggcagagg cgacgccagt acatatggca cctccaatac
     3361 cttcgacatc agcggggccg cgatcgattt gggatgataa acgaggcggg gggagccgga
     3421 agccccgaac cgcgttccat tcttcgtcga acatcaccgg ttcccatatt tcagcagctt
     3481 caagccggcg ccgaaaccct tgccgccagc gacggacccg cagaccaaac cgaccgcagg
     3541 cgcaggtcat ttgcgacgag gcatgacaaa cggatcaagc gcgatcctgc ccccgccaaa
     3601 cacgaccaat gccaacgcca tcgccgccca aggcagatgg aaattggccc aaccgtcggg
     3661 aacggtgagc tggatgatcg cggtcatcag cagcaagccg agtgatgcga agcgcgttgc
     3721 aaatccaagg atcagcaaaa tcggcaggac gagttctgcg atcccggctg ccgccgccat
     3781 cgccaatgga aacggatagg gaatttcgct gccgaagaca tggagtttga actcttgctc
     3841 gaatagaaac ctcgcacccg gcgaaagcgt taggaacccg tcccattttg tcaggcccga
     3901 cttgaagaag ggtatcgcga gcgcgaagcg cagtgccagc agcggcagcg aggggggaac
     3961 ggaggcgagc aggccttcgg tgcggatgat caaggcggca aggacagcgc cagagccgtg
     4021 tgagggtgcg gcttcagtct tcatgggacg tttccttcat cctgttggag ggcactgaac
     4081 gcgccgaggc agacaagacc catcagtgcc gccccgaaat tgaatgcggg gccagcggca
     4141 aatgccgccc cggccgctgc gccaagggtg gcatggttga acaaggaggt tgcaaagatg
     4201 acgtcctgcg gcggcaggat atgaacttcg accgtcatct ccggccgtgc gaccaggact
     4261 acctgcggcc gccagtcggc gaccggtgtt accatctcct catgatgcgc gctccagatg
     4321 gagccgatgg ggtattccga ccggatcagg gccgctgaag ggtgcgggac gagccgcaag
     4381 tccgcaagca tttcgggcgc cacagctgcg agtaccgcaa gtttgatcgg cacggcgtcc
     4441 gccgcgtagt aacttcgcgt ccaggccgcc tcgatccggg cgacatccgg cagataggca
     4501 agcttgctcg cgggctggaa gctcgcgatg aaatccggga aatcgtcgcc gtattcgata
     4561 atcagcggtg aagccggctt gtggtcctga gcataggccc gcgccatcgc catgaagaat
     4621 tccgtaccaa cgagccgctc cgtcaccgga aagcgttgcg ccagtgcctt tgacagcccg
     4681 acgaagacat tgttgcggta gacggcgaac cgtgctgcat caacttcgcc gcgtgcggtg
     4741 gtaatgccgt ccggtactgg cctgtcggcg tgcagcaatg cgtcggcaaa ggcagtctgg
     4801 ctggcggcga ggtccatcgt catgcggccc gaatccgacg tctggtgcgg cggagagctt
     4861 cggaggcaag cattgcatcc gcgcgtgccg cctccgccag caatgtcgcg aaatccggaa
     4921 cgtcattgtc ccattcaatc agcgtcggta aaggtccgct gcgcgcaagc gtgtgttcgt
     4981 agagcgccac cacatcgctc ttcaccgcag taccatgcgc gtcgatcagc aaccgctcgc
     5041 cggcgtcgtc aacggtctcg tcgtagccgg cgaggtggat ctcgccaacc aactcgaccg
     5101 ggaagcggtc gatataggtg gcggcatcga gacggtggtt cacggccgag accatcacgt
     5161 tgttgacgtc gagcaggagg ccgcaggcag tccgctccgc aatagtcgcc aggaagtcca
     5221 cctcatcgat cgtgctgtcg gcaaacagca cgtaggtcga tgggttttcg agcagcagcc
     5281 gtctcccgag ggtctgctgc gttgcgtcga tatggtcaat gacgcgggcg agcgtttctg
     5341 cggtataggg cagcggcaac aggtcgttga gaaaacctgt gtcatgggtc gaccaggcca
     5401 gatgttcgga gaaactgtgc gggcggtagc gatcgatcag gtcgcgcagc cgcttcaggt
     5461 gctccttgtc gagcccgcgc gccgcgccga tcgacaagcc gacaccgtgc agcgacagcg
     5521 gatagaactg cgtgatggct tccaggtagt gatgcggcgg tccaccggcg cccatgtagt
     5581 tctcggcatg cacctcaaag aagccgacat ccgggcgatc ggccagaatg gcgtcgtagt
     5641 gctggggctt gaggccaagg ccggcacgcg cgggcaaggc gtcggcttgg gtttttgaag
     5701 cggtcatggc ggttcctccc gatttgcaca gtggcggagg cccgggcagc cgggccaccg
     5761 cctgacgatt agcccttgat cggctcgagc ttgcccatat gaccatcgac attcatgctg
     5821 gtgcaggtac cggccggcac ggccttccag gcattgccct ggtagtccat tgtggaggta
     5881 ccggcgcagg tcgtgccggc gccggcggcg cagtcgttct gacccttgag cgcgatgcca
     5941 tagcacttct cgttgccgac cattttctca gccggcaacg gtgcggcgaa cgcaaccgac
     6001 gcaagagcgg cggcgagcga gccggcgagg gtaagggtga gcgtcgaacg gttcatggat
     6061 gatctcctct tggaacttcc gcggtccggt catcggccgc gtaaccttcc tttcgatccg
     6121 gtgaggcctt ctgttacgca cggctacgaa cacgagttcg tgatcgacaa tgcggcggtg
     6181 ttggacaata tttcgcgcgg cgcgtaacaa agcggcctgt acgcgcgtat tggagagaca
     6241 agggttgaac ggcgacgccg aaaatgaact tgccacgttg ctgcgcgctg cgatcgcagg
     6301 ggacgaaagg gcctatgccg aatttctggg acgcaccgcc gccattgtgc gcggcttcgc
     6361 gcgtcgcaag atacagggcg gcgtcgatcc cgaggacatc gtgcaggaaa cgcttctggc
     6421 acttcatatg aagcgtcata catggaagac cgacgcgcct gtctcgccct gggtttatgc
     6481 gattgcgcgc ttcaaactga tcgacgcgtt tcgcaagcgc ggccgccacg tggaggtcga
     6541 gatcggcgaa atcgccgaga cggtcgctca gccggaggcc gagacggtga gcgaccgcga
     6601 gattggtcgc gtgctggacg ggctgacggc cggccagcgt tctgtcgttg ccgcgatttc
     6661 gatcgagggg cgttcgatcg gcgagacggc cgccaagttc ggcatgacgg agacggcagt
     6721 acgagttgcc ctgcaccggg gtttgcgatc gatcgcaaag aagtttggac ggagctgaaa
     6781 tgcagaccaa cgacctcatc aatgccctga gggcagatgc agcaaagcag gcaatgccgc
     6841 ttggctattc atggtggatt gcgatcgtcg cagcgacaat cattgcggca ggcgccttct
     6901 tcatcctgat cgggccgcgc cccgacttca ccgtagccgc tcacacgccc cggttcctgt
     6961 tcaaattcat cgtcacgctc gcgctcgtcg tcgtcgcctt tgcgctcctg cgggtgttgt
     7021 cgcgtcccgg ttccgatgtc agacacgtcg cgtattggct cgttctgatg ccgattcttc
     7081 tcggcactgc ggtggcggcc gaattgttcg cggtgccttc tgatcagctg gttacggtct
     7141 ggtggggcag caacgtatat gtctgcctga ccttcatacc actgatcggc ctcggcgcgc
     7201 tggccgtgtt tctggcggca ctccgtcacg gcgcgccgac gcgcccccgc cttgccggcg
     7261 ccgtcgctgg cctgcttgcc ggcggcatcg ccgcaacctt ctatgcggcc cattgcaccg
     7321 acgattcacc actgttcgtc gcaacttggt attcaatcgc gattgccggc ctggtggcgc
     7381 tcggcgcgat ctgcggccgc cgcgttgccc gctggtagac gtcacggcgc tcgtccgatc
     7441 ctggcgccga tggaacgggc tgcaagtttg actgacagac gattgccgag ccatattcgc
     7501 ggcgaccgct tgcacggatt ttcgacgtca ctcgagaccg tgagtaagtg gttccgttct
     7561 gatcaggcat agacaagatt aggcgccacg atccactcgc cgggcttgag cactctcacc
     7621 gagacggcca gggcggtcgc ggagcgccaa tcccagaaat cgatagcaac tgacccgctc
     7681 cggcatgctg gccggttcac cggtcgaccg tgcgccgtac aacgttccta gccacatcct
     7741 ggaacggggt atccctagtg ggaagctgcg gtcgtcgacc acccacatgc aaacaaggac
     7801 cagggtatat attgcgaacg tgtcgccgat gggtcacgaa ggttgggata cgcttccccc
     7861 ggaagtgctg aaagctgtgc atgccaaaat cggtccgatc gctacgcctg acaagaccaa
     7921 atttgcgccg ggcctgctga agtcgcctcg caagataaag cgccgcattc tgcgctagct
     7981 cgccaaggaa gatttcggtg cgctcgtgct atgctcgacg cctgccgatc cggcgccgtc
     8041 gacaatctga tcgctaaccg gtaaaatagg gaagcacctg tttccatgca taccacggtg
     8101 gcagccaccg acagagccca gcagtcgggc aacccgcagc aataaatttc acaaagggta
     8161 tgggaaccca ggaaattgca acgcgttttt ccaaaaagcc acaccgcgag gctatccgaa
     8221 tgaacgacgt tcagcaactt cacgtttact atgattaccg cagcaaaacc gtcctggtcg
     8281 aattcgccga tcgaagccac gttcttgcgg aacgttttga agacaacgaa agtgcgcagc
     8341 agggggctat ccggtacgca gtaatgcagt ggggttatcg catgccggat tcgcaaaagg
     8401 agggtccggc tatggcattt gatcaacgaa tgcgcgacgg aagccagtca gccggataac
     8461 cggctgtcgc cggcaccgcc ggatgacagc ctgtcgtaga gttccgcata ctgttgcgcg
     8521 ctgcgttgcc aggggcagtc tgccttcact gcctgccgcc gcagttggtc aaaggcatga
     8581 tggtggcgaa acagcgtgaa agcgcgccgg aaggctgtcg caggccatcg gcgtcgattg
     8641 gcgagaactg aattcccgtt gctgcccgag catgcaaggc ggcgtcgttt gcatcgatca
     8701 ctgtttctga gagcccgccg gaccccgacg gcacaagcat cgcgtccgca ccaccgtgaa
     8761 gcaggtgtgc tatgcgttcc tcgtaaccga ttttcacggc gacatgctcc ggataacgtc
     8821 tggccgcctc ccgaaactga tcttcgatag gggcgtcgcc ctggccgttg atagttcagc
     8881 cgagacggcg agaatgtcca tgaggatgtt cctattcgag ccgaggcttt gcgaatttgc
     8941 tcgcggttcc atgcaacccg ctcgtgccgc ctcgtgttcc gtcagcggtc gtcaatttcc
     9001 ggccatgcaa atgcgacgaa ggcgagcctc ctctcagtcg gtctcgcgct aggaagctcg
     9061 gtgttcacat acctcgcgga cgaattgata aggaccgcgt ctcacatggc gaagtttccc
     9121 cagcttgcgt ttgcttggaa caaataccga tgggtttggg ttgcagggcg atgagaacac
     9181 caagcggagg cagctgtttg gcaagcaact gaccgcatcg gacacggaga atgctgatga
     9241 aacgtccaat gaagcgcctc tccgattgga agaggtcaat gttttggcgc cggcaacgca
     9301 agaaccgccc ggaaccacaa gtcatggtgc cgcaagtggt cgaccttgcc ttgccgaaaa
     9361 cgacccgtca ggaaatagca gtacccgctt ccatcaacgg caggagcttg gccgatgggc
     9421 gtccatgacg cgctggcggc agggcgttcg gcgatgtcac tgcccgatgt ggcccgggag
     9481 accttcttgg cggcagcgct tgaggtgagg tgccgcgtca aatcctcgac ggacagcgga
     9541 acggattcat gagatctggc gcgattgcaa tcgaaccggg acgctggcag caattgggcg
     9601 ccattcccga caccgacggc gtcaacttcg ccctgttttc cgcccacgcc gaaagggtgg
     9661 aactttgcct tttcgacgaa accggagcaa acgaaacagc ccggctcgaa ctgccggaat
     9721 acaccaacga agtctggcac ggttatgtgc ccggtttgaa gcccggcgcc ctctatggct
     9781 accgcgtgca tggcccctac gatccatccg ccggccatcg cttcaacccc aacaagcttc
     9841 tgatcgaccc ctacgcccgc gaattggccg gtgacatcgc atggtcgaaa gttcatttcg
     9901 gctatgacct cgcaagccag gacaaggact tatcgtttga tcaaagcgat agcgcctcca
     9961 gcatgccgaa gtgccgcatc gtcgaaccga acagctatga ctggaagtca gaccgccctc
    10021 ccgcaatacc gtggtcccgg accatctttt acgaagccca tgtgaaaggt ttcacccagc
    10081 ttcacccggc cgttccggaa aaactgcgcg gcactttcga ggggctcgcg gaaagggcga
    10141 tcgtcgacta tttgaggtct ctcggcatta cctcggtcga actcctgccc atccactatt
    10201 ttccagacga ccaacacctg atcgacaagg gtttgcgcaa ctactggggc tacaacagcc
    10261 tcgcgttctt cgcgccggcg agccgctact atggcccgcg cggtatggac ggccttcgcg
    10321 acatggtacg ggcgctgcat gacggcggta tcgaggtcat tcttgacgtg gtctataacc
    10381 acacggccga aggcaacgag cttggcccca ccctgtcctt caagggcatc gacaatttct
    10441 cctactatcg cacatggccc gacgatcatc gctactacat caacgacacg ggcaccggga
    10501 acaccgtcaa cacctcgcat ccgcgcgttt tgcaaatgat catggattca ctgcgctatt
    10561 gggtcgatga gatgcacgtc gatggatttc ggttcgacct cgggaccatc cttggtcgag
    10621 aaccggaggg gttcgaccag cgcggtgggt tcttcgatgc ggtgacgcag gaccccctgc
    10681 ttgcgaatgt caaacttgtg ggggagc
//
