LOCUS       NC_002695.2            10252 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_002695.2 Escherichia coli O157:H7 str. Sakai DNA, complete
            genome.
ACCESSION   NC_002695
VERSION     NC_002695.2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:08:59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1289425
            Orig. end    :: 1299677
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10252
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1294425:1294677](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5252
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10252
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10252
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="3"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             1235..1513
                     /locus_tag="ctg1_1200"
                     /transl_table=11
                     /translation="LEYGFAIYNRNNVNVTGVLTPVFFLDRFTAESGSKTYTNKPDGKS
                     LQAVCCLFPWNNVFADRKVPKITINDNTVTWSNLEQGMGSYIYTFWG"
     CDS             1519..2136
                     /locus_tag="ctg1_1201"
                     /transl_table=11
                     /translation="MYGLSIMKPDGSVWISPGFTPQCLINKGTIPATEKSFFKTSIPSG
                     KSCFFFIRTEKKADVMYTHEQIDGYHALRLHVIVRGTNPGVTTVYAFANMVTPPSEYGI
                     AMYNPDGEMIYHGEMMLLDAKLIPVDIKFEKDLGYPCAIMPALVGYYNWKRTPYDRPIY
                     TTSTGATGNKIYSCEHYSGGATWDIRKPYIDKVLVINTSVYD"
     CDS             2227..2961
                     /locus_tag="ctg1_1202"
                     /transl_table=11
                     /translation="MKSIATLVVCAISGIACVNLSAHAAEGEHTISLGYAHFQFPGLKD
                     FVKDATAHNRETFSHFVNRNYFSSLGEYTDGRVSGYEGKDKNPQGINIRYRYEITDDFG
                     VITSFTWTRSLTNSQTFIDVQSADHTRKIKNPAASARTDIRANYWSLLAGPSWRVNQYM
                     SLYAMAGMGVAKVSADLKIKDNINSSGGFSESNSTKKTSLAWAAGAQFNLNESVTLDVA
                     YEGSGSGDWRTSGVTAGIGLKF"
     PFAM_domain     2488..2958
                     /aSDomain="Ail_Lom"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06316.13"
                     /description="Enterobacterial Ail/Lom protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1202_0086"
                     /evalue="2.30E-31"
                     /label="ctg1_1202"
                     /locus_tag="ctg1_1202"
                     /protein_end="244"
                     /protein_start="87"
                     /score="109.2"
                     /tool="antismash"
                     /translation="PQGINIRYRYEITDDFGVITSFTWTRSLTNSQTFIDVQSADHTRK
                     IKNPAASARTDIRANYWSLLAGPSWRVNQYMSLYAMAGMGVAKVSADLKIKDNINSSGG
                     FSESNSTKKTSLAWAAGAQFNLNESVTLDVAYEGSGSGDWRTSGVTAGIGLKF"
     CDS             3194..3334
                     /locus_tag="ctg1_1203"
                     /transl_table=11
                     /translation="MSQKSLITVTICMTVIFTIWMLHGSLCEFRLNLWGAEFAAFLQCK
                     Q"
     PFAM_domain     3215..3325
                     /aSDomain="HOK_GEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01848.18"
                     /description="Hok/gef family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1203_0087"
                     /evalue="7.40E-10"
                     /label="ctg1_1203"
                     /locus_tag="ctg1_1203"
                     /protein_end="44"
                     /protein_start="7"
                     /score="38.4"
                     /tool="antismash"
                     /translation="TVTICMTVIFTIWMLHGSLCEFRLNLWGAEFAAFLQC"
     CDS             3391..3792
                     /locus_tag="ctg1_1204"
                     /transl_table=11
                     /translation="MAPVSGERMNDKILWYMQRVVRNSRNPEFMNEVKDACLKKQAFCF
                     EAPDGFLVLRSVLSADGIPYVLVLLGVCTGSNSVERYLPEVKTLTHLAGGRWAEFHTAR
                     RGFIRLGKRLGFERMPDDEDGFMVFRIAV"
     CDS             3886..4542
                     /locus_tag="ctg1_1205"
                     /transl_table=11
                     /translation="MGGSKGGGDTKVKPTAAQIAQEEVAWKGWQDYKNILRPAEDNFME
                     KVDDLNSEQQYDNIAGTTNLGYQKQFGEARKELAGNLAQSGVDPSSGRFNAVMNANQSD
                     QVTGQIDTTTRGQVSQADKYVAGLQDVAALGSGQKADALQSFNSLADSSLAKAKSDAQA
                     AFTKQQGRASLVGAGLGAAGAYAMHKAGGSGGSGGAKTPGTGANAIQHQAQNWRL"
     CDS             4545..4991
                     /locus_tag="ctg1_1206"
                     /transl_table=11
                     /translation="MEYGKYETLARAGYSGADRPQGDWQTSAALTRQQYDDWRTRYLPR
                     VARLADLGENNSLMNAQLARVGGLATSSLRTAQMAQDNQMARYGVNRPDNPDSNTLGLR
                     NALAIAGAKNGIREAEQDRQMNILTGASAPARQKLSVGGQLVAA"
     CDS             5001..5252
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1207"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 8.1e-07,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGYGLLDIANQSRREALQGISDADRRREEIEAANKQMAAQQKAQN
                     KQNIGTGIGTGAAIGASVGGPVGAVAGAVIGGIAGSLF"
     CDS             5263..6528
                     /locus_tag="ctg1_1208"
                     /transl_table=11
                     /translation="MSGFAQGLLAGFSTVDQAMTRRKELGLREAQLARQQKNNERDFEF
                     AQSQFEHNKNVDQRNFDYRAKVDDRNYALKEREFNANQNYRNASLGMEQQRLQLQKYNQ
                     RRLEYNDMIAHSQPLMEALGKAIEAGDQEAATRLFGQLPKGHPLILMSNEGYAAKAGQA
                     VINLQKIFGDKPDMAIDSLNTPENLDVLSGVFAPELQQRIGMPDSTGDKTIKEARIGSI
                     VPAQQEGYVLIGLDLTYSDGSTAHKPVTEYGSAHPDDQTVLAIPVDKAIAQVRDRSKFA
                     EISKNYGYFMPKQQGLSLKELQKGASNVAADAIKNGGNAQAAVDEYYAATGSQPHQQKI
                     QQQKLQQQVINWAGDDPDKLSFARNVAARQPEMLEPQNQKLLENGYANFLRIQKARGEQ
                     ARDESASSASQFIRGLKQNYAQ"
ORIGIN
        1 agaatatgga aattggcacc gggcagcgtg gtgacggacg tcacgcattt gtgacccgtg
       61 aggaactggt tggtcttaaa ctcgcccggc gtcgaacatc gggtggtgcc tcatatgcac
      121 tgaatccggg tattgagatt gacagtactt taatgactgt tgattttccc acaaaaccgc
      181 tgaattttaa ggcgaccggt ggatttggct cggttcttct tgaatgggat atgcctaatt
      241 atcgcggaca ttcactgact gaaatctggc ggggtacgga ggatgacctt gctgatgcag
      301 tgctggttgc cacgacgccg gggcaggttt acggcgatcc ggttgaccct ggctggtcgg
      361 gattttactg gatacgtttt gttaacgcgg caggagtgaa aggtccatgg aatgctgaaa
      421 aaggcactca ggcacaaaca cagatcggcg tgaaggccat cattgaccag atccgcgatg
      481 aggctgcaaa gtcgccggtt gtgtccgagc tgcgtaaaga aataaaaaac gcgcaggggc
      541 aggctgtaaa ggatgctgca attaagacaa ccgaagttgt agggactctc agggaagaaa
      601 cgacaagaac gattggtggt attgaaaccc gcattagcac actggattcg tcaaccagtg
      661 aatcgcttaa tgaggtcgac aagcgcatca ctaaattgga taaagaaggc ggtgaagctt
      721 ttcttgcaat gtggtcaaaa aaagcgggag ttgatggtat cactgcgggg atcgggattg
      781 tcgccggaaa agacagtgaa ggcaggcctg taagtcaggt tgcaatttct gcgtcgcagt
      841 tgtttgtctt tgacccgaat aatccggata acacagccta tccgtttgcg gtatcaggtg
      901 gcaaggtagt gatcccgaaa gcgatgattt atgacgcggt gattgaaaca ctggtgtcgc
      961 ggaaggttgt ggcggatgag gtaaaagccg gggtaagtat cacttcgcca gttatccgga
     1021 gtgccgttat tcagaacgga aactttcagg ttgattctca gggtaacctg aatattggag
     1081 gccttttcag tgttacgtca caagggcaac tgacaattcg ttactctaat cagaatgtag
     1141 gactggtgat ccgcaatgat aaaattgagg tttatgacca gaatggacga ctggctgttc
     1201 gcataggcag attacgctga tcaggaggtg agtattggaa tacggttttg ccatttataa
     1261 cagaaataac gttaatgtta cgggcgtgct gactccagta tttttcctgg acagatttac
     1321 agcggagtct ggctcaaaga cgtacactaa taaacccgac gggaaatcat tgcaggctgt
     1381 atgttgttta tttccctgga ataatgtatt tgcggatcgg aaagtaccga agataaccat
     1441 taatgacaat acggtgacgt ggtcgaatct tgagcagggt atgggatctt atatttatac
     1501 attctgggga taagtgttat gtacggtttg agcattatga agccggatgg cagcgtatgg
     1561 ataagtccag gttttacgcc gcagtgtctg atcaacaaag gcaccatacc ggcgactgaa
     1621 aagtcttttt ttaaaacatc aatcccgtca ggcaaaagtt gttttttctt tatcagaaca
     1681 gagaagaagg ccgatgtcat gtacacgcat gaacagattg atggatatca tgcactaagg
     1741 cttcatgtaa ttgtcagggg aacgaaccct ggtgttacga cggtttatgc tttcgcgaat
     1801 atggttactc caccttctga gtatggtatc gccatgtata acccggacgg tgagatgatt
     1861 tatcatggcg aaatgatgct gcttgacgcg aagttaatac ctgttgatat caaatttgaa
     1921 aaggaccttg gatatccatg cgcaatcatg cctgcactgg tcgggtatta taactggaaa
     1981 agaactcctt atgatcgacc gatttatacc acatccactg gtgctacagg aaataaaata
     2041 tattcctgtg agcattattc cggtggtgca acatgggata ttcgaaagcc gtatatagat
     2101 aaggtcctgg ttattaatac atcagtatat gattagttga agcgagtctt taatattcat
     2161 ttaaaatgtc taaaaagatg tattattaaa aagtttagcg tgttatctga atacaggata
     2221 tcttaaatga agagtatagc aacactggtt gtgtgtgcaa tctccgggat tgcctgtgta
     2281 aatttatctg cacatgcagc agaaggagag catacaattt ctctggggta tgcgcacttt
     2341 cagtttccgg gactgaagga ttttgtaaag gatgcgactg ctcataacag ggagactttc
     2401 agtcatttcg tcaacagaaa ctacttttct tcattgggcg aatatacaga tggtcgggtc
     2461 agtggatatg aaggcaagga taaaaatcca cagggcatta atatcaggta tcgctacgag
     2521 ataacggatg attttggcgt tatcacctct tttacatgga cgcgttctct cactaactca
     2581 cagacattta ttgatgtgca gtcagccgat cataccagga agattaagaa tccggcagct
     2641 tctgccagaa cggatatcag ggcgaattac tggagtctgt tagcggggcc ttcatggcgg
     2701 gttaatcagt acatgagttt atatgcgatg gcagggatgg gcgttgctaa agttagcgct
     2761 gacctgaaaa ttaaggacaa tattaacagt agtggcggat tttctgaaag caacagcacg
     2821 aaaaaaacct cccttgcgtg ggctgcaggt gcacagttta acctgaatga gagtgttaca
     2881 ctggatgtgg cttacgaagg ttccggctct ggcgactggc gcacgagtgg cgttactgct
     2941 ggcattggcc tgaaattctg acctgtatcc ggtaaccgtt tactacccgc tgtgatggcg
     3001 ggttttttat tgcccgtaca gggcaaaaac cgtaaattat gcgtgggtgc ctttcggctg
     3061 atggctggag ggtgaacctg aaggcctgat gtggaaaggc cccgagtcaa cttaacgtta
     3121 acccgaggcc ctaacacttc gtaccttaag caagtagaag gttagcgcct ctctgtaaaa
     3181 ggagtcaagc gctatgtcgc aaaaatcgct tatcaccgtc acaatttgca tgacggttat
     3241 cttcaccatc tggatgttgc acggttcact gtgtgagttc cggctgaatt tgtggggagc
     3301 ggagtttgcg gcgttcttac agtgtaagca gtaggaaaac cgcgacgggg acgagagtcc
     3361 ccgtcaactg gttgctgagg ttcagccgat atggcacccg tttcaggtga gagaatgaac
     3421 gataaaattc tctggtatat gcagcgtgtt gtgagaaatt cccgcaaccc tgaatttatg
     3481 aatgaagtta aagacgcctg ccttaaaaag caggcgtttt gttttgaggc acctgatggc
     3541 tttttggtgc tgcgttctgt gctcagtgct gatggtatcc cttatgttct ggtgttgctg
     3601 ggcgtgtgta cggggagtaa cagcgttgag cgttacctgc cggaggtgaa gacattaacc
     3661 catctggctg gcggacgctg ggctgagttc catacggcaa ggcggggatt tatccggctg
     3721 ggaaaacgac tgggctttga gcgaatgccg gatgatgagg atggcttcat ggtgttcagg
     3781 atagcggtct gactgctaca gttttcatca ttgtgtttaa accaacattg taattcacat
     3841 tctgaccctg ctccggcagg gttttttgtt atccaggggg ccattatggg tggaagtaaa
     3901 ggcggtggtg ataccaaagt aaaaccaaca gcagcgcaaa tagcacagga agaagtggcc
     3961 tggaaagggt ggcaggatta caaaaatatc ctccgcccgg ctgaagataa cttcatggaa
     4021 aaggtcgatg acctgaacag tgagcagcag tacgacaata ttgctggcac cacaaatctg
     4081 gggtatcaga aacagtttgg cgaagcacgg aaggagcttg cgggtaatct tgctcagtcc
     4141 ggcgttgacc catccagtgg tcgttttaat gcggtaatga atgcgaacca gagtgaccag
     4201 gtaaccgggc agattgacac aaccacacgg gggcaggtat cgcaggcaga taagtatgtt
     4261 gccgggctac aggatgttgc tgctctcggt tctggtcaga aggcggatgc gttacagagt
     4321 tttaactctc tggcagacag cagtctggca aaagctaaat cggatgcaca ggcggcgttt
     4381 acgaaacagc aggggcgagc ctctcttgtt ggcgctggtc tgggtgcggc aggtgcatat
     4441 gcgatgcata aggctggcgg tagcggagga agtggcggtg ctaaaacacc tggcaccggc
     4501 gctaatgcca ttcagcatca ggctcagaac tggagactgt aattatggag tatggcaaat
     4561 acgaaactct cgcaagggct ggttattcag gagcagaccg cccacagggt gactggcaga
     4621 cgtcagcagc gctgacacgc caacaatacg acgactggcg aaccagatat ttgccccgcg
     4681 tggcaaggct ggctgacctt ggggagaaca acagtctgat gaatgcacag cttgcacggg
     4741 tgggaggcct tgccacttcc agtctccgta cagcgcagat ggcgcaggat aaccagatgg
     4801 cgagatacgg ggtaaaccgc ccggataatc ccgacagtaa tacgctgggg ttacgtaatg
     4861 ccctggcaat tgctggcgcg aaaaatggta tccgtgaagc cgaacaggat cgccagatga
     4921 atattctgac gggggcttct gcaccggcaa gacagaaact gagtgttggc ggccaactgg
     4981 tggcagcgta agggggcaat atgggatacg gtttactgga tattgcaaat cagtcgcggc
     5041 gtgaggcatt acagggaata agtgacgcag acagacgacg tgaagaaatt gaggctgcga
     5101 acaaacagat ggcggcgcaa cagaaagcgc agaacaagca gaatatcggt acgggcattg
     5161 gtacgggggc ggctattggc gcatccgttg gtggtcctgt tggtgctgtt gctggagcag
     5221 taattggcgg cattgctggt tctttgtttt aaggagtggt gaatgagcgg atttgcacag
     5281 gggttacttg ccggattcag caccgttgac caggcaatga cccgtcgtaa ggagcttggt
     5341 ctgcgtgaag cacagcttgc ccggcaacag aaaaataacg agcgcgattt tgagtttgcg
     5401 cagtctcagt ttgaacataa taaaaacgtt gatcagcgga actttgatta cagagccaaa
     5461 gttgacgacc gtaattatgc actgaaggag agggagttta acgctaacca gaattaccgg
     5521 aatgcgtcac tgggtatgga gcagcagcga ctccagttgc agaaatacaa ccagcgacgg
     5581 cttgagtata acgatatgat tgcccatagc cagccactaa tggaagcgct tggaaaagca
     5641 attgaggctg gcgatcagga ggctgcaacg cgtctgttcg ggcagctgcc aaagggacat
     5701 ccattaattc ttatgtcaaa cgaaggctat gcagcgaaag cgggtcaggc cgtgatcaac
     5761 ctgcaaaaaa tctttggtga taagccggac atggcgatcg attcgctgaa taccccggaa
     5821 aatctcgatg tgctttccgg cgtgtttgcc ccggaactac aacagcgtat tggcatgcct
     5881 gattcaaccg gggacaaaac gataaaagag gccaggattg gcagtatcgt accagcgcag
     5941 caggaagggt acgtacttat tggccttgat ctcacataca gcgatggctc caccgcgcat
     6001 aaacctgtaa cagaatacgg cagtgcgcac cctgatgatc aaaccgtgct ggcgataccc
     6061 gttgataagg ctatcgctca ggtcagggat cgcagcaaat ttgcagagat atcgaaaaat
     6121 tatggttatt ttatgccgaa gcagcaggga ctttctctga aagagcttca gaagggggcc
     6181 agcaacgtag cggcggacgc gatcaagaat ggcggtaatg ctcaggctgc ggtggatgaa
     6241 tattatgctg cgactggttc acaaccgcat caacagaaaa ttcagcaaca aaaacttcag
     6301 caacaggtta tcaactgggc gggagatgat cctgataagc tgtcatttgc cagaaatgta
     6361 gcggcccgtc agcctgaaat gctggaacct cagaatcaga aattgctgga gaacgggtat
     6421 gcgaattttc tccgtattca aaaggccagg ggggaacagg ccagagatga aagtgcttca
     6481 tctgcatctc agtttatccg tggactgaaa cagaattacg cccagtaatt cacgatattc
     6541 cattaatacc atttcctgat gcccggccat tgtgccgggt ttttttatgg agtctgtatg
     6601 gcctattcag aggaacagcg tcctgaggcg caactcggta accagaatcg taacagcctg
     6661 aacattcagc aacccggcga aactgacagc tatgaagcat ttttctctga tccgaatcgc
     6721 tggaaggata acagtacgtc gttcagcctg ggcgatgtat tgccaacaat gggtaaaggt
     6781 ttcgcccagt ccgtccgggg aacaggggaa atggcccgtg gactcggtga tgcgatgatt
     6841 cagagcccgg taaaaacagg ggcgcgtatt ttaaatgagt tcagccgtat ggggctgccg
     6901 ggtgtcgcaa ctgtgcagga tatttttgcc ggtggcagca ggggggctga tgaggtcatc
     6961 gataccctgc ctgatggcaa aaacgcggtt actgatactg tcggtaaagg tctgaaggca
     7021 accggtaagg ctgtcagtga tggtgccaaa gccactgatg aatggctgac cggtaagatg
     7081 tcgccgggtg cagttcgtgc gctgaatacg ccgatgaccg aaggctataa tgattctgcg
     7141 gtctgggtgg cgaagggtgt aaacctgatt ggtgcgcttg tacctgatat ggttgctggc
     7201 ggtgtggcta gaaaggtggg tgatgtcaca ctgcgaaaaa tgctgaccgc cgggctggag
     7261 aaaaaataca tcgcggcagg gatgcagccg gaaagagcca cggcactggc agcagaagct
     7321 gtcgataaaa aaatgccgga tttattccag gcgggcctga tcacccattc cactgtaagt
     7381 gcacaggggc agagtgcaat ggcggcagca gatgctgttc ttaatgctga ttactctgag
     7441 ctggcgcagt caccgaaatt tcagcagacg tttttgtcca ttgacgccga cccgcagcac
     7501 gcacagctta ctgatcgcca gaaaatggat ctggcaaaag agcgtgttgc cgatgaggtg
     7561 cgcgcgcagc tggcaaccga tcctgaattg ctggctgtga atgccatggc ggcaaaactg
     7621 ggtgacgcac aactgtttaa tctggtgaca cgaggcacag cgaagaccgt taaaagcggc
     7681 attgtcagaa atgccacgga acagggggcg attaatgcgg cgcagggcgg ctattcacgc
     7741 tatcaggaaa acacggcatt gcgtgagacc gccggaatgg gtgtgtcacc gtgggagggc
     7801 gtggctgacg caacgatcga aggtgcagcc tttggtgctg cgatgggggc tccattcggt
     7861 gcggttgccg gatatcgtgg cagacgtcag gccgcagaag aaaccgccat gcgtgatgct
     7921 gaaaccgtgc agcaggacga cgcagccccg caaccagaat ctgttgatcc ggtggcgcag
     7981 cagcgtgaat ccatgcaggg catgaatcgc gagcagcttc tggagcagta tgctgatgcg
     8041 gatatggcaa cagagggtga cgcatccgca gctcatcgcc gggaagctgc cagccagttg
     8101 ttgaatgaac tggacgaaca gacgaagcga caggctgtga tgaatgagct gaaggcgaag
     8161 ccgcgttctg aactgcttga ggaataccgc agactcagcc agaaagaggg gcgcaccgag
     8221 actgaagaac aacagtttca ggcaatacga gaagtcattc gcccacaaca ggaagtgacg
     8281 ccggaagcac agtcacagcc tgaaaatgcg gaggatggta acgggagcat ttacccgacg
     8341 gtgcggttcc gggacccgaa tgaagtccgc attgaaatta acgggaatgg tgcgtccaga
     8401 ccagcggaac gcattgagaa ggtgcgcccg gacaaccgtt atttcacgga tgagaaaagc
     8461 gccatgggga gtgatgtttt ccgtaatgcc gccgccaccg gcctgaaacc gtccgtagtg
     8521 aagaaaggcg agaatcagta tgccgttgaa atggataatc ctgcgttctc tgaagatgtg
     8581 gcaacggaaa ccattaacac cctggctgac ggagagcgta ttgctgatgc tgacccgatg
     8641 gagcagcccg cgttcatgcg tgacccgcga ttccgtggtt tcacggggga tgatacggag
     8701 gtacaggccc gccttgcccg tggcaacgcg ccgacggcag aggagcttgt acgttcacag
     8761 atggctgaag gtgatgccgg tccgacagca caggagttaa ctgagcgtcc acgcctgccc
     8821 gctcccggcg atattcatcc cggacaggga tatccgttac cgggagaagt ggcgcgtacg
     8881 ccggatgaaa atcaggccgg acgtggtggt cgttttacca caaccggtga ggttaagggc
     8941 cagagtttcc agaaaggaca agctccggca ccggaaaacg ccgctggtcg ccagggggaa
     9001 acactcgagg gtgacatggt tcgtcgtggt ctgccgtcac cggatgcgca gaacgcgaca
     9061 gcaccggtac gtgaagggct accggctcct gacattgcgc gtaatgttcg tatgcctcag
     9121 cctgaatcac ttccccgcac tgtacgggac tcactgcctg agcttgcaca gcaggcagaa
     9181 gtacgccgac aggccggagg aaatcgtgac atcccgcagc ctgagacaat cgcacctgaa
     9241 tctgaaacaa ctgtctctac tgacagggaa gctaccgtgc gcggaggtga agtcaggggc
     9301 aaaaaaattg aagactttgg tgaagaaatt aagggcgcgg caaaacaccg ttatgcacag
     9361 cttgctgaaa cactgggtaa aacgctggaa gacagggatt atgccacgca gccgctgagc
     9421 aaactgttcc cgaaaccgga ctacgcaaaa ctggcgaacg aaggtgctga tgctgatacc
     9481 ctggcaatga tagcgctgta tcgtagcgat attccggcga agacgaaaca caatacggca
     9541 ggctgggggg agagcataaa aaaagtacga cacagtgtat cggaaatgct gaacggaacg
     9601 gtcagcgcga aacgcctcgc agaatggatg gaaggcagaa tgccctcccg ttacgcggat
     9661 acctggcaac tgttacgcac tctgccaccc tcacagatgg acagggcttc tgcttatcgg
     9721 gtggtatcgg gtgtgtatca ggcggcagga gggaagcgtt acgatccgcc acagaaactt
     9781 tattcactgc gcaataagga caataagggg agtaacctct ttttctcgga aagcagggat
     9841 gaattactgg caaaggcgaa agtctggttt gcagagcagg aggaaaaatc acaggcgaaa
     9901 ggtgatgaaa aaacagcacc gtcaccggat gacaaaatcc gctttgacgt ttaccggaat
     9961 acccgcagtg gcgatatttt tatcgcttac ggtaaaaaca aaatgcgggt gagaggtggc
    10021 tttaagtcag ccagtgatgc gcgtaagtac attgattcac atcgtgatga gcttgttcgt
    10081 catgtgaagg agatgcggga gatttcgcgt gaggagcagc gcaacgccac caaccgcgac
    10141 cgtaccggac cagaacgccg caaggggaat gtttcaccgg agcagttcag tgatgcgttt
    10201 ggtttccgtg gtgtgcagtt tggtaactac gtggaaggtc cgcgtcgtca gg
//
