LOCUS       NZ_CP033719.1          11902 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP033719.1 Propionibacterium acidifaciens strain FDAARGOS_576
            chromosome, complete genome.
ACCESSION   NZ_CP033719
VERSION     NZ_CP033719.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:51:56
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1951568
            Orig. end    :: 1963470
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11902
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1956568:1958470](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6902
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..11902
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11902
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="7"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(220..1512)
                     /locus_tag="ctg1_1627"
                     /transl_table=11
                     /translation="MADMKRNRVFRGFPVPFRMRWGRAGRGRPGGDRRPGRVEEAFRQS
                     CAGADEGRSGPARLPRRRCGHHRRDGRAHGEDRAGTAGRLAGHQDAPGPGRARGEPGRD
                     GTRPRPEARTRDHPGPAAPPRRVPAPGSETSRPCGDAVTCGDAVKILSDGRYQSGPSHQ
                     LLPPLCGPSPEPPDPFDEHRDEPATTRRMAWATTRVKSLSGQGWKAHTARLRPAPSTRP
                     GPAGCSPQRTAHQSGPWTGRGRPSPSPAPSPPTSRTVTPYPTEGNQNTWQTILAPDRLQ
                     RETETEKIAVVPDNARPPPRESVDRPPPAGSTAGAHHPCFPAAVRARPQPRRERPEHGQ
                     EQHREHSARDPRRNPRRVRLTRHRTHRRPRLRAPPTPRNQKRSCSMTAIEPNHYSFHLL
                     SQSAPSWTCEQRTTTTTTKLLPLLPLRVVFA"
     CDS             complement(1660..2727)
                     /gene_functions="other (smcogs) SMCOG1238:transposase
                     (Score: 102.2; E-value: 5.6e-31)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1628"
                     /transl_table=11
                     /translation="MQVEVTPEETAVLIRWKKRSDNYVLVRMKAEAVLYASEGVSISII
                     AKMVERTERTVLEWLAEWRATRMCSVLTGHAGNQNAAKLTRAQKEELKAILAQPPSRSG
                     VHAEFWDVPAIREVVKIMFDVEYQSDSSYQLLLRLCELSLELPDPFDKHRNEKAITRRM
                     AEVKAQVKSLLDQGWEAYTADEARPEHEAETRRMWLPRGQRTKLYVDRKKTSQSFFGAL
                     SLTSKKVKLYPIEGNQNTAQTILALDRLQRETETGKIAVVLDNARFHHAKALTDLYEPG
                     QLLERITPIHLPPYAPDHNPAGHVRNTAKNNTVTIQHETPEETLGASAPYVTGRSFDHD
                     SEHLPLRETRNDFVS"
     PFAM_domain     complement(1792..2187)
                     /aSDomain="DDE_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13358.8"
                     /description="DDE superfamily endonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1628_0207"
                     /evalue="3.40E-18"
                     /label="ctg1_1628"
                     /locus_tag="ctg1_1628"
                     /protein_end="312"
                     /protein_start="180"
                     /score="65.9"
                     /tool="antismash"
                     /translation="YTADEARPEHEAETRRMWLPRGQRTKLYVDRKKTSQSFFGALSLT
                     SKKVKLYPIEGNQNTAQTILALDRLQRETETGKIAVVLDNARFHHAKALTDLYEPGQLL
                     ERITPIHLPPYAPDHNPAGHVRNTAKNN"
     CDS             3503..3904
                     /locus_tag="ctg1_1629"
                     /transl_table=11
                     /translation="MTDFVVLTVCCMVLGAVAFCCALLASTGVLPRNGWVGTRLGPTPA
                     SDAAWRAGHRAALRWGIVAVVDDVCCLTVGFVLLLVDDGVRRAIWGPRTAFVIDVLTAF
                     PYVFSAYRAARGVAADQKHDGATKAVPRV"
     CDS             5001..6902
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 157; E-value: 1.1e-47)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1630"
                     /sec_met_domain="TIGR03975 (E-value: 1.7e-105, bitscore:
                     350.9, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.5e-15, bitscore: 53.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVSIVVPPAANPDWPSMGAEVIAAVSRRAGHDTTVHYAQLLQPK
                     GDSLEEFSISTAGLYSPTYFGQSVPQFAQELAAAVHADLRVLRPQLGDAGIAPPDYMTK
                     RYIRAMNAARDVVRRAVVEILDDSPDVVGFSITLDVQKMPAAAIARGLREKGFSGRLVA
                     GGSAMDGRSPLAFLRTFTEFDAVLVGEADESWVSCLDRINAGRTDLAGIPGILCRKGST
                     VLVGPPERPPEDLDGCATPDYRDYIRQYEASEWSQDGGSVLVLESSRSCWWGARSRCTF
                     CAIDSRTRPYRTKSSDRTIAELRKLWVTYSPRVVLYTDSIFPYSYREDHLARLAEDSRS
                     DCWSLFYETKSTVPRRTIARFACAGVREVQPGIESFSTRTLRHMRKGATALQQVNFLKW
                     CSAYGVHAGYGLIAGTPGETAEDLRQVLSVLRAIEHLDAPEQLNWLLLFQTSDYYEQRD
                     SYGFQDVQPLEAERLAYQAPESVLQDLVSMYRYTLPSHRDPEYLAAFRAVEEWIAAHHS
                     SARAPSLTADDCGDCILIIRRALNGAQSLTAVADAAELFLLRECAEVRSLPGLIRNGPY
                     DSDALLTAAERLVTAGLMLVDGTWMLALPIPVDAEASVDAAWPAHITQPKRKEECPS"
     aSDomain        5007..6818
                     /aSDomain="TIGR03975"
                     /aSTool="tigrfam"
                     /description="rSAM_ocin_1: ribosomal peptide maturation
                     radical SAM protein 1"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1630_0025"
                     /evalue="5.30E-106"
                     /identifier="TIGR03975"
                     /label="ctg1_1630"
                     /locus_tag="ctg1_1630"
                     /protein_end="606"
                     /protein_start="2"
                     /score="353.4"
                     /tool="antismash"
                     /translation="VSIVVPPAANPDWPSMGAEVIAAVSRRAGHDTTVHYAQLLQPKGD
                     SLEEFSISTAGLYSPTYFGQSVPQFAQELAAAVHADLRVLRPQLGDAGIAPPDYMTKRY
                     IRAMNAARDVVRRAVVEILDDSPDVVGFSITLDVQKMPAAAIARGLREKGFSGRLVAGG
                     SAMDGRSPLAFLRTFTEFDAVLVGEADESWVSCLDRINAGRTDLAGIPGILCRKGSTVL
                     VGPPERPPEDLDGCATPDYRDYIRQYEASEWSQDGGSVLVLESSRSCWWGARSRCTFCA
                     IDSRTRPYRTKSSDRTIAELRKLWVTYSPRVVLYTDSIFPYSYREDHLARLAEDSRSDC
                     WSLFYETKSTVPRRTIARFACAGVREVQPGIESFSTRTLRHMRKGATALQQVNFLKWCS
                     AYGVHAGYGLIAGTPGETAEDLRQVLSVLRAIEHLDAPEQLNWLLLFQTSDYYEQRDSY
                     GFQDVQPLEAERLAYQAPESVLQDLVSMYRYTLPSHRDPEYLAAFRAVEEWIAAHHSSA
                     RAPSLTADDCGDCILIIRRALNGAQSLTAVADAAELFLLRECAEVRSLPGLIRNGPYDS
                     DALLTAAERLVTAGLMLVDGTWMLALPI"
     PFAM_domain     5829..6284
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1630_0208"
                     /evalue="5.30E-14"
                     /label="ctg1_1630"
                     /locus_tag="ctg1_1630"
                     /protein_end="428"
                     /protein_start="276"
                     /score="53.0"
                     /tool="antismash"
                     /translation="SRCTFCAIDSRTRPYRTKSSDRTIAELRKLWVTYSPRVVLYTDSI
                     FPYSYREDHLARLAEDSRSDCWSLFYETKSTVPRRTIARFACAGVREVQPGIESFSTRT
                     LRHMRKGATALQQVNFLKWCSAYGVHAGYGLIAGTPGETAEDLRQVLS"
     CDS             6899..8020
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1631"
                     /sec_met_domain="Fer4_12 (E-value: 8.7e-06, bitscore: 23.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSRMVAHEKEMMTFSVTDQCNVRCAHCLALCSPKQTTMLTADE
                     MYESYLSIAATRPVRTVVFTGGEPTLLGEELLEAIARISLEGPVTRVVTNASWATDDDA
                     ANVMVQQLRSAGLAEINFSMDDYHASWIPPENVRRAFDASRGQGFEAVVIALAEGPRST
                     ITREWVQHEIAPGVQFVDQRSSRAGAHPPRSADGTLYEIAHHGYSRVGRARGFGEEDIV
                     PDESMLAQYCCCAEILSQPVVDARLDAGICCGLSVRNNRVLRIGSLRESTYAELADAAQ
                     HDVLIRALRFLGPKYLLDVARSIDPRVRMRPEYAGICEVCEDVTASRRALAALDTAKAR
                     IALDVALAERAQQGDDDRILGRDAELRTAHAGT"
     PFAM_domain     6947..7366
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1631_0209"
                     /evalue="1.30E-08"
                     /label="ctg1_1631"
                     /locus_tag="ctg1_1631"
                     /protein_end="156"
                     /protein_start="16"
                     /score="35.5"
                     /tool="antismash"
                     /translation="SVTDQCNVRCAHCLALCSPKQTTMLTADEMYESYLSIAATRPVRT
                     VVFTGGEPTLLGEELLEAIARISLEGPVTRVVTNASWATDDDAANVMVQQLRSAGLAEI
                     NFSMDDYHASWIPPENVRRAFDASRGQGFEAVVIAL"
     CDS             8007..9107
                     /locus_tag="ctg1_1632"
                     /transl_table=11
                     /translation="MPGHDPLERLGLHLERVGLADLLCSYTPAAQTSALTDSVIPPGLL
                     PLVELFCLGREVPEADLDPVIVPALEDLTNAGFATRSGPRPTWSIRDLVLQRVHGLWLL
                     AGRPSAQRTLYFGADSLALADRIPLVGGSALDLCSGPGFQSLWLASRGMRVTGCEINER
                     AVHLCGVNARLNGVQDRVHPLRSDLYAELPEGSFDVVVANPPMVAVPPGIPYPFVGDGG
                     PDGFGVILRIIEELPGRLAPRGNAYTLGVAAAGDELPLALDALRSEARRLGLRMRLTVT
                     SEHGAGSGSTWDRAIAATSLSFEGSAVTQSSLEERTIQVSQGYADLGAHRVVFFFMAVA
                     EEQHGSVGILDVRAEHPQNHQGWYAA"
     PFAM_domain     8376..8627
                     /aSDomain="MTS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05175.16"
                     /description="Methyltransferase small domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1632_0210"
                     /evalue="4.30E-12"
                     /label="ctg1_1632"
                     /locus_tag="ctg1_1632"
                     /protein_end="207"
                     /protein_start="123"
                     /score="46.1"
                     /tool="antismash"
                     /translation="ADRIPLVGGSALDLCSGPGFQSLWLASRGMRVTGCEINERAVHLC
                     GVNARLNGVQDRVHPLRSDLYAELPEGSFDVVVANPPMV"
     CDS             9143..9547
                     /locus_tag="ctg1_1633"
                     /transl_table=11
                     /translation="MNGISITAWVIFWANIVATLSVAATSRFQSRPKVEPTHWAGIRVG
                     ATMKSSEAWRAAHPAAFRWSRLDVIGVCGAVLICLLLLPARWLVLAECVVFACCIVSLG
                     LNTWHAVKAAEKVLSWDYEHLRGRGRNEKM"
     PFAM_domain     9239..9448
                     /aSDomain="SdpI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13630.8"
                     /description="SdpI/YfhL protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1633_0211"
                     /evalue="1.30E-08"
                     /label="ctg1_1633"
                     /locus_tag="ctg1_1633"
                     /protein_end="102"
                     /protein_start="32"
                     /score="34.9"
                     /tool="antismash"
                     /translation="KVEPTHWAGIRVGATMKSSEAWRAAHPAAFRWSRLDVIGVCGAVL
                     ICLLLLPARWLVLAECVVFACCIVS"
     CDS             10116..10508
                     /locus_tag="ctg1_1634"
                     /transl_table=11
                     /translation="MSDVTSTGWIMFAANIILPVAVFLSYYFQVRPGGRPNRWAGIRIR
                     VVASSPEVWRAAHRAAFRWERVNVICFCGAAVICLLTLRSWHLVLAECIIFGGYVISFL
                     LNFWHTSTMAGKMAHSQRRHDEDRGS"
     PFAM_domain     10218..10403
                     /aSDomain="SdpI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13630.8"
                     /description="SdpI/YfhL protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1634_0212"
                     /evalue="4.10E-08"
                     /label="ctg1_1634"
                     /locus_tag="ctg1_1634"
                     /protein_end="96"
                     /protein_start="34"
                     /score="33.3"
                     /tool="antismash"
                     /translation="RPNRWAGIRIRVVASSPEVWRAAHRAAFRWERVNVICFCGAAVIC
                     LLTLRSWHLVLAECIIF"
ORIGIN
        1 gcccagccgc cacgccgaaa cccctaccta caccctcatc cgggaagagc catcaaacgg
       61 cgaaactcag gatttccctt cagggggctc gtctcgtttc cctgggatct ccctgagggg
      121 cacgctcata cgcgccaaag aggcctcatg aaaccgtctc acccccttga cacgggtgct
      181 cggtcgggtg tctcgttaaa aatgatggat gcttctcctt cacgcgaata cgacgcgtag
      241 gggcaagagt ggcaagagtt tagttgtcgt cgtcgtggtg cgctgttcgc aggtccatga
      301 cggggctgac tgggaaagaa gatggaaact ataatgattc ggttctatgg ctgtcatgga
      361 acaggatcgt ttctggtttc gcggggtggg aggtgctcga agtcgtggtc gacggtgtgt
      421 ccggtgacgt gtgaggcgga cgcgccgagg gtttcttcgg gggtctcgtg ctgaatgttc
      481 gcggtgttgt tcctggccgt gttccggacg ttctcggcgg ggttgtggtc gggcgcgtac
      541 ggcggcagga aaacaggggt gatgcgctcc agcagttgac ccggctggtg gaggccggtc
      601 aacgctttcg cgtggtgggg ggcgggcgtt gtccgggacg accgcgatct tctctgtctc
      661 ggtttctcgt tggagccggt ccggtgcgag gatcgtctgc caggtgttct ggttcccctc
      721 ggtcggatac ggcgtgactg ttctgctggt cgggggggag ggcgccggag aaggactggg
      781 acgtcctctg ccggtccacg gaccgctctg gtgcgctgtc ctctgggggc tgcatccggc
      841 gggtccaggc ctcgtgctcg gggcgggcct cagtcttgcg gtgtgggcct tccagccctg
      901 gcccgacaag cttttgactc gggtcgtcgc ccaggccatg cgtctggtgg tggccggctc
      961 gtcgcggtgc tcgtcgaacg ggtcgggcgg ttcggggctc ggcccgcaca ggggcgggag
     1021 cagctggtgg gaggggcccg actggtaccg gccgtcggac aggatcttca cggcgtcacc
     1081 gcaggtcacg gcgtcaccgc agggccggga cgtctcggaa cccggcgcgg gcacccgtct
     1141 gggaggggcg gccgggccag gatggtctcg agttcttgct tccgggcgcg ggcgggttcc
     1201 gtcgcgtcct ggttccccgc gtgcccggcc gggacccggc gcatcctggt ggcctgccag
     1261 tcggccggcc gttcctgcac ggtcctctcc gtgcgctcga ccgtctctgc gatggtgccc
     1321 gcatcgacgc ctcgggaggc gtgcaggacc gcttcggcct tcatccgcac cagcacatga
     1381 ttgtcggaac gcttcctcca cccgaccagg acggcggtct cctccggggc gaccccgacc
     1441 cgcacgcccc caccgcatcc gaaacggcac aggaaatcca cgaaaaacac ggttccgttt
     1501 catgtcagcc atacatggaa tccttgctaa aaaggaggct tattaacagg ggaccagatc
     1561 gcgatcatcg cccctgatca cagcgtaatc cacaggcgct gtgaataaac cttcaggatc
     1621 gtgaagcgag actttgaggg ttatttaaaa ctatggccgt catgaaacaa aatcgtttct
     1681 ggtttcgcgg agtgggaggt gttcggagtc gtggtcgaag gagcgtccgg tgacgtatgg
     1741 ggcggacgcg ccgagggttt cttcgggggt ctcgtgctgg atggtgacgg tgttgttctt
     1801 ggccgtgttc cggacgtgcc cggccgggtt gtggtcgggc gcgtacggcg gcagatgaat
     1861 cggcgtgatg cgctccagca gctgacccgg ctcgtagaga tcggtcaatg ctttcgcgtg
     1921 gtggaagcgg gcgttgtcca ggacgaccgc gatcttgccg gtctcggttt ctcgttggag
     1981 ccggtccagg gcgaggatcg tctgcgcggt gttctggttg ccctcgatcg ggtacagttt
     2041 gaccttcttg ctggtcaggg agagcgcacc gaagaacgac tgggacgtct tcttccggtc
     2101 cacgtacagc ttggtgcgct gcccccttgg gagccacata cggcgagtct cggcctcgtg
     2161 ctcggggcgg gcctcgtctg ccgtgtaggc ctcccagcct tggtccaaca agctcttgac
     2221 ctgggccttc acctcggcca tgcgccgggt gatggctttc tcgttgcggt gcttgtcgaa
     2281 cgggtcgggc agctcgagac tcagctcgca caggcgcagg agcagctggt acgaggagtc
     2341 cgactggtac tcgacatcga acatgatctt cacgacctca cgtatcgccg ggacgtccca
     2401 gaactcggcg tgaacaccgg accgggaggg cggctgggcc aggatggcct tgagttcttc
     2461 cttctgggcg cgggtgagtt tcgccgcgtt ctggttcccg gcatgccctg tcagcaccga
     2521 gcacatccgc gtggcccgcc actcggccaa ccattccagc actgtccgct ccgtgcgctc
     2581 aaccattttc gcaatgatgc tgatactgac tccttcggag gcgtacagga cagcttctgc
     2641 tttcatccga accagcacat aattgtcgga acgcttcttc catctgatca ggacggcggt
     2701 ttcttccggg gtgacctcaa cctgcatgcc tcaatcatat ccgaaacggc acagaaaatc
     2761 cacgaaaaat acgatttcgt ttcatgtcag ccatagctcg ttatcaaggg agaaccaaga
     2821 ttggatctga caaggatttt aataaacctc tttgcataag tttttagatc gaaaggttgc
     2881 caatggctaa ttttgtggca ttagctgttt gctgtgcaat agttggagct gcattatttt
     2941 gcagtgcttt ttttgcttcg aggggaattt taccaagaaa tcgttggatt gggattagat
     3001 taggattcac gctttcgagt gatgtcgcat ggagaatagg gcatcgagca gcattgaaat
     3061 ggggtgctgt ggctgttatg gatgatgttt gctgcttgac ggcagggttg gtgcttcttc
     3121 tctatgatgg agggccgcaa agagctgtct ggggcccggg tgcggcactt gcctctaatg
     3181 tgttaatttt tgtcccatat ctcgtatctg cgtacaaggc gacgagagat gtctcaacga
     3241 ttgataatca ttagaaattc acagataagc ttggtcagtg ggatcatggg ggcttgttcg
     3301 cagaacccat ggagggtgct tcgaccagga gctgtggtcg tgattcaacc cctgtgaatg
     3361 agtctcatgg aatgaagcct tgcacaagcc tcgcggcttc tgcgactgct gagggtgtgg
     3421 caggaaggcg gcgcctctgc atgggccctg cgaaccagga cccgaaggat tctgcctctg
     3481 tttcacatga ggggagcggg tcatgactga tttcgtcgtg ctgactgtct gctgcatggt
     3541 gctcggtgcc gtggcgttct gctgtgctct tctcgcctcg accggggtgc tgccgaggaa
     3601 cgggtgggtc gggacaaggc tcgggcccac ccccgcgagc gatgccgcgt ggcgggccgg
     3661 gcacagggcg gcgttgagat gggggatcgt cgcggtcgtg gatgatgtct gctgcctgac
     3721 cgtgggattc gtgcttcttc ttgtggatga tggggtccgc agggcgatct ggggtccgcg
     3781 caccgcgttc gtgatcgatg tgttgaccgc cttcccgtat gtgttctccg cgtacagggc
     3841 ggcgaggggc gtcgcagcgg accagaagca cgatggtgcg acgaaggcgg tgccgagggt
     3901 gtgattcttc cgcggcccgg ccccgcgtct gacggctcgc gcgggcgccc gcgcgtccgg
     3961 gcccgtttcg gttctgcgtg gttccacggc aagaactcca ccggaaacca tttcgtccgc
     4021 agagggttgt tcacaggagg ctcgacggaa gggtaatcct tggttgcggg ctgatccatg
     4081 gggctgtgaa tgggtctcac ggtccgtccc ggttccgagc gatctcgcgc ggaacagacg
     4141 ggacgcatcg accgactcgg cgggcgatcc catgcggtga acagcccctg cgccccaggc
     4201 ggctcccgcc cgatcggccg accgtcacca cccgctgcgc cggtccctcg ctcgacaagc
     4261 cctgacgagg gctggtaccc gccgctggcg ccgccggtct cggcagccgc gccggtctcc
     4321 ccgctcgaca agccttgatg agcaccgtgc ttgacgagca ccgtgctgca cggcccctgc
     4381 tccgggtctt tccagggggc cgtgcccgtg ggcgccgccg ggcacgcgga tcgccccggc
     4441 gcggacgggc acacgctgtc gggcgaccgg ccccgatggt ggctgtgcgc actgatccgg
     4501 cggcatgcga gcggtgttcc ggcgggggct gcgcccgcgg ctccccggcg tgagaattca
     4561 ggcatgcata acctgattca atggtgagaa cgtagtcttt tctcggggtt ctcccccgat
     4621 tccctgaaat caccctgagt gatgcgttca tgcacggcct ggagcttctt cggggccgtt
     4681 cggaagtcct tgacagtgga acgcgtcggg gtgttctgtg aagtcacggt gcttccacgg
     4741 ctgctggccg tcagaggcgg tcgtcgccga atgcccgtgc ggaacccgtg gcatcaccgg
     4801 tgatggaaga agatgagatc gacatgatcg gatcgacatg atcggtatgt ccgttgctgc
     4861 tgagatccgg aactcatggg gccgccggac aggcgcgtcg tcctttgcgg tgcgatgtga
     4921 ttcccctgtg ttggggggtc gtgcggtggt gcttactgca ggggagtcat ccccggtctc
     4981 ctaaggaagt gagggcgccc atgcgtgtca gtatcgtggt tccaccggcg gccaatcctg
     5041 actggccgtc catgggtgcc gaggtgatcg ctgcggtgag ccgtcgtgcc gggcacgaca
     5101 ccacagtgca ctatgcgcaa ctcctccagc cgaaggggga ctcgctcgag gagttctcga
     5161 tctcgacggc tgggctctat tctcccacgt acttcgggca gagcgtgcca cagttcgccc
     5221 aggaactggc tgcggctgtc cacgctgatc tcagggtact cagaccccag ctcggtgatg
     5281 ctgggatcgc tcctcctgat tacatgacga aacgatacat ccgcgccatg aatgctgctc
     5341 gtgatgtggt gcggcgtgcc gttgttgaga ttctcgacga ctccccggat gtcgtcggtt
     5401 tcagtatcac tctcgacgtt cagaagatgc cggcagcggc catcgcaagg ggtctgcgcg
     5461 agaagggatt ctccggtcgt ctggtggccg gcggctcagc catggacggc cgatcgccat
     5521 tggcgttcct gcgaacattc accgaattcg acgccgttct ggtgggcgag gccgatgagt
     5581 cctgggtgag ctgtctggac cggatcaacg cgggccgcac ggatcttgct ggcatcccgg
     5641 gcatcctctg ccgcaagggc tcaactgtcc tcgtcggccc gccggagagg cccccggagg
     5701 atctcgacgg gtgcgcgacg ccggactatc gggactacat ccggcagtac gaggcgagcg
     5761 agtggtcaca ggacggtggt tccgttctcg tcctcgagtc ctcgagaagc tgctggtggg
     5821 gggccaggag cagatgcacc ttctgcgcga tcgacagcag gacgaggcca taccgtacga
     5881 agtccagcga ccgaaccatc gctgagctcc gcaagctctg ggtcacctac agcccacggg
     5941 tcgtgctcta taccgactcg atattcccgt actcctaccg tgaggatcat ctcgcccggc
     6001 tcgctgagga cagccggagt gattgctgga gtctcttcta tgagacgaag tctacggtcc
     6061 cccgacggac catcgcccgc ttcgcctgcg cgggtgtacg ggaggttcag cccgggatcg
     6121 agagcttcag cacgaggacg ctgagacaca tgcgcaaggg cgccaccgcg ctccagcagg
     6181 tcaacttcct caagtggtgt tcggcgtacg gcgtccatgc cggctacgga ctcatcgccg
     6241 ggacgcccgg tgagacggcg gaggacctcc ggcaggtgct gagcgtcctg cgggcgatcg
     6301 agcatctcga cgccccggag cagctgaact ggttgctcct gttccagacg agcgactact
     6361 acgaacagcg cgactcgtac ggcttccagg acgtgcagcc gctcgaggcg gaacggctgg
     6421 cctatcaggc tcccgaatct gtcctccaag acctcgtgtc catgtaccgt tacacccttc
     6481 cctcccatcg ggatccggag tacctcgccg cattccgcgc ggtcgaggag tggatcgccg
     6541 ctcatcattc ttctgcgcgg gcaccctcgc tcaccgctga cgactgcggg gactgcatcc
     6601 tcatcatccg tcgcgcgctc aacggcgcgc agtccctcac ggccgtggcg gacgccgcgg
     6661 agctcttcct gctgcgcgag tgcgccgagg tccgctccct tcccggcctg atccgaaacg
     6721 gcccctacga ctcggacgcc ttgctgaccg ccgccgaacg cctcgtgacg gccgggctca
     6781 tgctcgtcga cggcacatgg atgctcgccc tgcccatacc cgtggatgcc gaggcctccg
     6841 tcgatgcggc atggcccgca cacatcactc aacccaagag aaaagaggag tgcccatcat
     6901 gacatcatcc cggatggtcg cccatgagaa ggagatgatg accttctcgg tcaccgacca
     6961 gtgcaatgtg agatgcgcgc actgcctcgc cctgtgctcg ccgaaacaga cgacgatgct
     7021 caccgccgat gagatgtacg agagctatct gtcgatcgca gcgacgcgcc ccgtgagaac
     7081 ggtggtcttc acgggaggag aaccgaccct cctcggtgag gagctcctcg aggcgatcgc
     7141 ccgaatcagc cttgagggcc cggtgacccg cgtcgtgacg aacgcctcat gggcgacgga
     7201 tgatgacgcc gcgaacgtca tggtgcagca gctgagatcg gccggcctcg ccgagatcaa
     7261 cttcagcatg gatgactacc acgcctcgtg gatacccccg gagaacgtca gacgcgcctt
     7321 cgacgccagc cgagggcagg gcttcgaggc ggtcgtcatc gcactcgccg agggaccgcg
     7381 gagcaccatc accagggaat gggtgcagca cgagatcgcc cccggagtgc agttcgtcga
     7441 ccagcggtcc tccagagcgg gtgcccatcc tcctcgttcg gccgatggga ccctctacga
     7501 gatcgcccat cacgggtaca gccgggtcgg gcgcgctcgg ggattcggcg aggaggacat
     7561 cgtgcccgat gagagcatgc tcgcgcagta ctgctgctgc gctgagatcc tcagccaacc
     7621 ggttgtcgat gcccgcttgg atgccggtat ctgctgcggg ctgagcgtga ggaacaaccg
     7681 ggtgctgcgc atcggctccc tccgtgagtc gacatacgct gaactggctg acgcggctca
     7741 gcatgacgtc ctcatccgtg cgctcagatt cctggggccc aaataccttc tcgacgtcgc
     7801 gaggagcatt gatccgcggg tccgcatgag gccggagtac gccggcatct gcgaggtgtg
     7861 cgaggacgtc accgcgtcgc ggcgcgcact cgccgccctg gacacggcga aggcgcgcat
     7921 cgccctcgac gtcgcgctgg ccgagagggc ccagcagggc gacgatgacc ggattctcgg
     7981 tcgtgacgca gaactgagga cagcccatgc cgggacatga tccgctcgaa cggctcggcc
     8041 tgcatctgga gcgggtcgga ctggctgatc tgctgtgcag ctacacaccc gctgctcaga
     8101 cgagcgctct cacggactcg gtgatcccgc ccggcctgct accgctcgtc gagctcttct
     8161 gcctgggccg tgaggtgccc gaggcggacc tggacccggt gatcgtgccg gctctcgagg
     8221 acctgacgaa cgccgggttc gcgacgcgga gtggaccacg gccgacatgg tcgatccgtg
     8281 atctcgtgct ccagcgggtc cacgggctgt ggctcctggc cggcaggccg tcggctcagc
     8341 ggaccctgta cttcggagcg gactccctgg cgctggctga tcggatcccc ctcgtcgggg
     8401 gctctgccct ggacctgtgc tcggggcctg gttttcagtc cctctggctc gcctcccgcg
     8461 gtatgcgggt gaccggatgc gagatcaatg agcgggccgt tcatctctgc ggcgtgaacg
     8521 cccggttgaa tggcgtccag gaccgggttc accccctccg ctccgatctc tacgcggagc
     8581 ttccggaggg gagcttcgac gtcgtcgtgg cgaatccgcc gatggtcgcc gtcccgccgg
     8641 ggataccgta tcccttcgtc ggggacggcg gcccggacgg attcggggtg atcctccgca
     8701 tcatcgagga actgcccggg cgtcttgcgc cccgaggaaa cgcctacact ctcggggtcg
     8761 ccgcggccgg cgatgagctc ccgctcgccc ttgacgcgct gcggtccgag gcccgccgtc
     8821 tcggtctgcg gatgagactc acagtgacct ccgaacacgg tgcaggatcc ggcagcacct
     8881 gggacagggc cattgccgcc acatcactca gtttcgaggg ctcggcggtc actcagtcct
     8941 ctctcgagga acggaccatc caggtttccc aaggctacgc ggatctgggg gcccacaggg
     9001 tggtcttctt cttcatggcg gttgccgagg aacagcacgg atctgtcggg attctcgatg
     9061 tccgtgctga gcatccgcag aatcatcagg gttggtacgc cgcgtgactg ggcgcgagtt
     9121 agagaatatg aggagcagca agatgaacgg aatctcgatc acggcttggg tgatattttg
     9181 ggccaatatc gtggcgacgc tgtcagtcgc tgcgacgagt cggttccaga gccgtccgaa
     9241 ggtcgaaccc acgcactggg ccggaattcg ggtcggggcg acgatgaaat catccgaggc
     9301 gtggcgggcg gcgcacccgg cggccttccg ttggtcgaga ctcgatgtca tcggtgtctg
     9361 cggcgccgtc ctgatctgcc tgctcctcct cccggcgcgg tggctcgtcc tggcggagtg
     9421 cgttgtcttc gcctgctgca tcgtctcgct cggactcaac acatggcacg ccgtcaaggc
     9481 ggccgagaaa gttctttcgt gggattatga gcacctccgt ggaaggggtc gaaatgaaaa
     9541 gatgtgaggg ggcaaggcga tgaccggtat ttcgagtacc ggatggataa tgttcatgct
     9601 cgatatggtg ttgctggtgg cggctgtcct gacttattat gctcagagtc ggcccagggc
     9661 caagcccaat cgttgggctg gtattcggat cagggtggtg gcgagttcgc cggaggtgtg
     9721 gcgggcggcg caccgggagg ccttccggtg ggagagggtg aacctcgtct gcttctgcgg
     9781 ggcagcggtg atctgcctgc tcacgctcag gtcgtggcat ctggtgctcg ccgagagcat
     9841 tctctattgc ggctatctca tcccgttcgg gttcaacgtc cggcatgcct gcgcggtggc
     9901 gagaagaatg gtcgattccc agagtcgccg tgaggatggg gcccgaccca tgatggttgc
     9961 cgagggcggg ttcgccggct gcgggggcgt acgagtgggt gcctcgcgtc gtgtccgagg
    10021 tgccgatgga tggcgtcctg atcggacggg gtgctcttgg tcagggcttc gcgatcgggt
    10081 catgcaggag ttgacaggga tgaggaggta atgcgatgtc tgacgtcacg tccactggat
    10141 ggatcatgtt tgcggcgaac atcattcttc cggtagcggt ctttctgtcc tactattttc
    10201 aggtgaggcc cggcggtagg cccaatcgtt gggccggtat caggatcagg gtggtggcga
    10261 gttcgccgga ggtgtggcgg gcggcgcacc gggcggcctt ccggtgggag agggtgaacg
    10321 tcatctgctt ctgcggggcg gcggtgatct gcctgctcac gctcaggtcg tggcatctgg
    10381 tgctcgccga gtgcatcatc ttcggcggct atgtcatctc gttcctgctc aacttctggc
    10441 acaccagcac gatggctggg aaaatggctc actcccagcg ccggcatgac gaggatcgcg
    10501 gctcatgaca ggcgtcctga ccggctggcg tgctcgtggt cagggccttg tacacatgac
    10561 gcggtgcatc acgtgcctgt ccgtgatgac tgcgatggtc gtcctctcgt ccttcccggt
    10621 tcctgcgtcg gctgatgcgg gtggcgctga tgcaacgccc cggggcgctg ccccgagtcc
    10681 gttcgactgg ggcccgtgct cctcggatcg gggtgatcag agcgtcgagt gcgcggtcgt
    10741 cactgttccc ctgaaccact cggatccttc ggttgggagt actgcggtga gggtggggag
    10801 gattcccgcg actggtggca acgccagggg gacgatcttc tacaaccctg gtggccccgg
    10861 cctctccccg gtcgagggcc tggcatcctt cgcggccaag ctgagcccgc aggtcagggg
    10921 tgaccacgac atcatcggtg ttgacccgcg cggcgtcggc ggctcggagg gcattccctg
    10981 cggggccatg accacggagc ccccgtcgac ctcctacagc gtcctccccg cgaacgccga
    11041 gcagctggcg gagcagttcg acgccctcga cccgtggctg cgggggacct gcgattccga
    11101 ctcgcccctt ctcaagcatg ccgggagtgt cgacgcggca cgcgacatcg agcaggtgag
    11161 atgtcttctc ggggtcgacc ggatcgacta ctacggcatc tcgtacggag ccgtcatcgg
    11221 cgccgtgtac agccggctct tcccggcgca tctgcgcacc ctgaccctcg acagcccgga
    11281 cgacccgaac gcctggttcg gtgcgggcca gcccgacccc ctgtgggccc ggctcggcac
    11341 ggcggagtac agcgggaaga ccctggagga cctgttcagc gcctgcgagt cggcgggcag
    11401 ccgttgccag tgggcaccga tgatccgatc cgactacgag cgcgtgacca gggcactgcg
    11461 gacggagagg ctcacggtcc cgggaacggg gagcttcgac gcctcggcgt tccagagcac
    11521 ggtcgtcagc gcgctgtacc ggttcaacca gaacggccgc gatgactacg agacgctgct
    11581 cggtctcatc catgccttgg cccaggtcgc cgacggcacg gcgccggatg gggaacccgc
    11641 atcaggcgat tctgtgatcg gtccgcagac tcgcgccggg tcaggggcgc catcgcagga
    11701 cacgacggtc tcccggatgc tcaccgtgga cgcggtgatg tgcgccgacg cccatgagcc
    11761 gccgcagcgg gaggcatggt tcatgagcgc cgcggccgcc gaggcggaca gcccgggatt
    11821 cggttactac tggatctccc aggactctat ctgcaacggc tggcccgcca ccgggaacct
    11881 cgaggattct gtcggcattc cg
//
