LOCUS       NZ_CP033719.1          22733 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP033719.1 Propionibacterium acidifaciens strain FDAARGOS_576
            chromosome, complete genome.
ACCESSION   NZ_CP033719
VERSION     NZ_CP033719.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:51:56
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1479983
            Orig. end    :: 1502716
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22733
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1489983:1492716](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12733
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     cand_cluster    1..22733
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22733
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="5"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     CDS             complement(505..771)
                     /locus_tag="ctg1_1241"
                     /transl_table=11
                     /translation="MMALARPTMMVAVPELYEAAMAGARAEAGDSGPRRRLVDWSLGVV
                     AAVQAAYNRGERPRCATVCGSSWPTGSSWAGSGPRSAGRRGCS"
     CDS             complement(1277..2071)
                     /locus_tag="ctg1_1242"
                     /transl_table=11
                     /translation="MSVLIGAHVDEEDPVGEAAARGADIVQISLGDPRSWKGPVLAHGG
                     GPQALRRAAADAGLALVVHAPFVINVASTNNRIRVPSRRLLQKHVDMAAELGALGVVVH
                     GGHVTAEDDPGAGYENWAKAVAGLDAAVPILIENTAGGRHAMARRLESIDRLWTALAAV
                     DGGDRVGFCLDTCHAHGAGLGLDGLVDRVRAITGRIDLVHANDSRDEPGTGADRHANLG
                     QGLADAEAIARIVATAGAPAVVETPGGAEAQAADIAWLRARI"
     PFAM_domain     complement(1286..2023)
                     /aSDomain="AP_endonuc_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01261.26"
                     /description="Xylose isomerase-like TIM barrel"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1242_0167"
                     /evalue="1.00E-38"
                     /label="ctg1_1242"
                     /locus_tag="ctg1_1242"
                     /protein_end="262"
                     /protein_start="16"
                     /score="133.6"
                     /tool="antismash"
                     /translation="EAAARGADIVQISLGDPRSWKGPVLAHGGGPQALRRAAADAGLAL
                     VVHAPFVINVASTNNRIRVPSRRLLQKHVDMAAELGALGVVVHGGHVTAEDDPGAGYEN
                     WAKAVAGLDAAVPILIENTAGGRHAMARRLESIDRLWTALAAVDGGDRVGFCLDTCHAH
                     GAGLGLDGLVDRVRAITGRIDLVHANDSRDEPGTGADRHANLGQGLADAEAIARIVATA
                     GAPAVVETPGGAEAQAADIAWLRA"
     CDS             2075..5599
                     /locus_tag="ctg1_1243"
                     /transl_table=11
                     /translation="VSLVGARGGAPTGPAGTRERSPRTVKGPASIRRERLRKARERGRR
                     TPGRPRRTARACCGDPVRTLRPGPVRAPRLDRMNAHLDHDPAASAPLRWLARLDDEVLL
                     NHYPQRSVERGAAYAERSGVVTDVRLGPDALSGHVQGTLSSPYDTSIRFICAGRRVITW
                     SDSCTCPKGRDCKHAVALLMSARSAAQLVLEGRAAASAPAPTSSWERVMARLAPEQGGT
                     RKLAVVFEDAGIAGYDYVSSGRWRLHLLRTGVDGDWVGKRVRWRDLVEAPAMVQARSDQ
                     RAAVVGLAQLLGSGDAHAANRVTLESLPSEVWAQLRRAVDAGVELLHDLGDRRHARVHL
                     DPTKASLGLNLAAAGDDYELQVLLSRDGRPEPFRPGWTLLGEPAHGILRTEPRGELRLT
                     ELDRSVDPALRPLLEAAPSLALPADDLPRFLGLYAPQLRSNLRLTSSDARVDIDAPPTG
                     GLWVQLDFSRPGRLALRSGVALASAGHSTRLELERCPAGLMDEGARLLLDRVRDLVGGQ
                     TAELTGRALLDFVTRELPALEDDPHVLVECIGVRPEYTELTGEPRLAVEVLDAEPDADD
                     AALATSAVEDAALDGSTDWFGLSVVVTIDGRELPVAALLAALTAGDDHVMLDDGAWIDL
                     ARPGLDPLRRLVEEAARLVDPGTGEMRLSRWDLGTWQDLEASGAITAASARWRRSVAAL
                     GHLDEIAPPDVPAAIGARLRPYQTEGYQWLAALWTAGLGGILADDMGLGKTLQTLALIA
                     RARETGELARPALVVAPTSVMAAWTGEARKFAPSLRVVVIDQTATKSGVPLARAVAGAD
                     VVVASYTLVRLDEASFTALEWSLLVLDEAQFVKNHTAKTYAVVRRLLARMRLVITGTPL
                     ENSLMDLWSLLSIAAPGLFPDPRRFQADIARPIESGDEPDRLALLHRRTRPLMLRRTKE
                     QVAAELPPKQEFVVPVTLGRAHRRIYDRELAATRMRVLGLLDDSSRTHRIEILAALTRL
                     RQLSLHPGLLDEADLAVGSEKIDSLAEQLHSLAQAGHRALVFSQFTGFLKLVRERLTAE
                     RIGWEYLDGRTRRREERVRAFKEGDATAFLISLKAGGFGLTLTEADYVFVLDPWWNPAA
                     ERQAIDRTHRIGQDKQVMVYRLVSADTIEEKVVELQQRKRELFDQVVGDEALSSGALTL
                     DDIRGLLA"
     PFAM_domain     2570..2623
                     /aSDomain="SWIM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04434.19"
                     /description="SWIM zinc finger"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1243_0168"
                     /evalue="7.80E-04"
                     /label="ctg1_1243"
                     /locus_tag="ctg1_1243"
                     /protein_end="183"
                     /protein_start="165"
                     /score="19.1"
                     /tool="antismash"
                     /translation="SCTCPKGRDCKHAVALLM"
     PFAM_domain     4265..5068
                     /aSDomain="SNF2-rel_dom"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00176.25"
                     /description="SNF2-related domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1243_0169"
                     /evalue="1.30E-59"
                     /label="ctg1_1243"
                     /locus_tag="ctg1_1243"
                     /protein_end="998"
                     /protein_start="730"
                     /score="201.7"
                     /tool="antismash"
                     /translation="GLGGILADDMGLGKTLQTLALIARARETGELARPALVVAPTSVMA
                     AWTGEARKFAPSLRVVVIDQTATKSGVPLARAVAGADVVVASYTLVRLDEASFTALEWS
                     LLVLDEAQFVKNHTAKTYAVVRRLLARMRLVITGTPLENSLMDLWSLLSIAAPGLFPDP
                     RRFQADIARPIESGDEPDRLALLHRRTRPLMLRRTKEQVAAELPPKQEFVVPVTLGRAH
                     RRIYDRELAATRMRVLGLLDDSSRTHRIEILAALTRLRQLSLHPGL"
     PFAM_domain     5102..5431
                     /aSDomain="Helicase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00271.33"
                     /description="Helicase conserved C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1243_0170"
                     /evalue="3.20E-13"
                     /label="ctg1_1243"
                     /locus_tag="ctg1_1243"
                     /protein_end="1119"
                     /protein_start="1009"
                     /score="50.1"
                     /tool="antismash"
                     /translation="KIDSLAEQLHSLAQAGHRALVFSQFTGFLKLVRERLTAERIGWEY
                     LDGRTRRREERVRAFKEGDATAFLISLKAGGFGLTLTEADYVFVLDPWWNPAAERQAID
                     RTHRIG"
     CDS             complement(5881..6510)
                     /locus_tag="ctg1_1244"
                     /transl_table=11
                     /translation="MMFGHRNGNGDRGGQGVPVEATRGLFWAWVANDLEELTTMGPWSR
                     RHGSELASRLAGRLPGGAPRRVSGGLSERHVRVSISIMGCLMLALAERGRATGGRSRLY
                     QVGLLGFGVHGFTHLLNSAVRRGYTPGVATAPTVVIPFSAWAVRELARNGVLRLDGRTI
                     TTALVGLPVTILGIHGLTARLVDPEDAPEDVAPGRTTPGERTTPGG"
     PFAM_domain     complement(6073..6432)
                     /aSDomain="HXXEE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13787.8"
                     /description="Protein of unknown function with HXXEE motif"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1244_0171"
                     /evalue="2.80E-13"
                     /label="ctg1_1244"
                     /locus_tag="ctg1_1244"
                     /protein_end="146"
                     /protein_start="26"
                     /score="50.7"
                     /tool="antismash"
                     /translation="WAWVANDLEELTTMGPWSRRHGSELASRLAGRLPGGAPRRVSGGL
                     SERHVRVSISIMGCLMLALAERGRATGGRSRLYQVGLLGFGVHGFTHLLNSAVRRGYTP
                     GVATAPTVVIPFSAWA"
     CDS             complement(6859..8907)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1245"
                     /sec_met_domain="PF00561 (E-value: 3.7e-05, bitscore: 20.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.5e-33, bitscore:
                     113.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGAGPMATISHVRSWTDQWEWLRNSPDELQRVLEDEAECSERV
                     LAGPARRADALVGVPVADLFYEQASQPAVRSGDFWYLMVLDGEAGSPSIMRVPHDSDEP
                     EPTATDLMSDPRAQVALNVAELAPGASLGSVVFSSDGRIVCWTEDPDGSESYRVHVTSV
                     AGQKELLDPIDGCSGSVVLDEKGSRVVWVGLDGTRRPAAVFAKSFSDGRVTVLHHECDE
                     RLRLRMKQCVSGDFLLLDAVSRTMVRHFISRLGAADLRLRQVAGLPFEGRSTLDVGELD
                     GRPALFATVATDDQPNGRLLVRFIDRLGGAEGDWRCLIEHDERSVLAPVLVTRRNLVIG
                     RRREGHQGIVIAKPTVPLTGIRSVRGATGSELSVTALPDWDGSVLRVGVSSYVHRPLSG
                     RVDLDETEPRVELAALNEDVYETKELFGETADGVRIPITLVGRRDRTGPAPCLLSVYGA
                     YGVNQRPNYNPLLLKLLDAGMVFAVAHVRGGGELGPRWHTVATGLGKPLTFTDVLACLD
                     ALVARRTADPNRVALIGGSAGGLAVGAVLNLAPERFRAVVADMPFVDPLTTMMHPDLPL
                     TISDRSEWGDPLADPRIFECIRGYSPCQNVRDAVYPRCLPRSGRGTRGFLRWRPSNGSV
                     RCAPLRGAGPSYCVFVPAANCMLHHSMRRFTTRLSSTHGSPISSALT"
     PFAM_domain     complement(7063..7494)
                     /aSDomain="Peptidase_S9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00326.23"
                     /description="Prolyl oligopeptidase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1245_0173"
                     /evalue="8.90E-32"
                     /label="ctg1_1245"
                     /locus_tag="ctg1_1245"
                     /protein_end="615"
                     /protein_start="471"
                     /score="110.4"
                     /tool="antismash"
                     /translation="LKLLDAGMVFAVAHVRGGGELGPRWHTVATGLGKPLTFTDVLACL
                     DALVARRTADPNRVALIGGSAGGLAVGAVLNLAPERFRAVVADMPFVDPLTTMMHPDLP
                     LTISDRSEWGDPLADPRIFECIRGYSPCQNVRDAVYPRCL"
     PFAM_domain     complement(7849..8871)
                     /aSDomain="Peptidase_S9_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02897.17"
                     /description="Prolyl oligopeptidase, N-terminal
                     beta-propeller domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1245_0172"
                     /evalue="1.50E-16"
                     /label="ctg1_1245"
                     /locus_tag="ctg1_1245"
                     /protein_end="353"
                     /protein_start="12"
                     /score="60.3"
                     /tool="antismash"
                     /translation="HVRSWTDQWEWLRNSPDELQRVLEDEAECSERVLAGPARRADALV
                     GVPVADLFYEQASQPAVRSGDFWYLMVLDGEAGSPSIMRVPHDSDEPEPTATDLMSDPR
                     AQVALNVAELAPGASLGSVVFSSDGRIVCWTEDPDGSESYRVHVTSVAGQKELLDPIDG
                     CSGSVVLDEKGSRVVWVGLDGTRRPAAVFAKSFSDGRVTVLHHECDERLRLRMKQCVSG
                     DFLLLDAVSRTMVRHFISRLGAADLRLRQVAGLPFEGRSTLDVGELDGRPALFATVATD
                     DQPNGRLLVRFIDRLGGAEGDWRCLIEHDERSVLAPVLVTRRNLVIGRRREGHQGIVIA
                     K"
     CDS             complement(8904..9623)
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 170.4; E-value:
                     5.1e-52)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1246"
                     /transl_table=11
                     /translation="MQQDESAGIDAPDPEDPGTVTVLIADDQAIIRRGLRDFLGESPDI
                     EVVAEASTGYEAVSLAHAWRPDVILMDLRMPKGNGLEATRQILAESDRSKILILTTFER
                     DEYLFVAMDLGASGFANKDLDLDDLSEAIRTVARGGCWLKPRLAARLAAEFANRKPVPV
                     PTAGAAPELLTVRERQVAALISDGLSNQQIARRLHLEVTTVKAHIGSIFNRLDMNNRVQ
                     IAIWAHDRQLVFSAEDE"
     PFAM_domain     complement(8943..9110)
                     /aSDomain="GerE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00196.21"
                     /description="Bacterial regulatory proteins, luxR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1246_0175"
                     /evalue="2.30E-16"
                     /label="ctg1_1246"
                     /locus_tag="ctg1_1246"
                     /protein_end="227"
                     /protein_start="171"
                     /score="59.2"
                     /tool="antismash"
                     /translation="LLTVRERQVAALISDGLSNQQIARRLHLEVTTVKAHIGSIFNRLD
                     MNNRVQIAIWA"
     PFAM_domain     complement(9222..9560)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1246_0174"
                     /evalue="8.40E-26"
                     /label="ctg1_1246"
                     /locus_tag="ctg1_1246"
                     /protein_end="134"
                     /protein_start="21"
                     /score="90.4"
                     /tool="antismash"
                     /translation="VLIADDQAIIRRGLRDFLGESPDIEVVAEASTGYEAVSLAHAWRP
                     DVILMDLRMPKGNGLEATRQILAESDRSKILILTTFERDEYLFVAMDLGASGFANKDLD
                     LDDLSEAIR"
     CDS             10001..12733
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 83.5;
                     E-value: 3e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1247"
                     /sec_met_domain="Pkinase (E-value: 1.6e-13, bitscore: 47.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="micKC (E-value: 4.8e-197, bitscore: 653.9,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 8.2e-07, bitscore: 26.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIPQVMTIPMETDPMDMKYLAFCYADPAFYDIKRDTTNGSGARR
                     FELPRDRDWTSWSLSTGNGWEYVMPPGMNMPEQGWKIHVSATMENAQKLLGDVASYCHA
                     SAVPFKFLPTRTELMRTNMKYAHRGSSGKFITIYPDDDEQCARIAAELDAIIGGAEGPY
                     ILSDIRYHGGPVYLRYGGFRPLLMRSRTDELSPAIRNPSGELVEDDRQPVFRPPEWVQI
                     PDFIRAQMDALNSGDRPEEFPYAVLDAMHFSNGGGIYRAIPDGQEHPVVLKEARPHAGI
                     SPDGTDAVARLLREAEFLDRLADLPEVVRCHRVFKAGEHCFMEEELIEGTTLNSEMVMR
                     SPEIRAGVGNREILDYRDWALAALAKVERTVHAFHEHGIVFGDLHPNNIIVTPDGDIRF
                     IDFEMAHDVDDPTSAPAGAPGYIAEDGRTGIAADLYGLGCIKLSMFVPLTVLLPLDHSK
                     LRGLVEHARQFYALSDEFCASIVADISLTVTDDNPAPLRRRARVARDAWCMDDPEAVAE
                     IDAAIVRGLDEALDLSRPDRVWPGDVSQFDEGGYGIATGACGVLLAHPEARQREDVLDW
                     IEETAADSSKTSFGFYNGLAGAAWTLDRLGRGEAADRLFEKVRTLHLPSLPSDLYSGLS
                     GIGICLMDQARRHNQHHYDETIAAIHEVMLDRFDEDRSSIVREVNGTATAAVGKGGLMQ
                     GMAGQALYWICSHEFTGDDTDPDRASTALDRDLALLVQTPDGSLQLNEGWRVLPYLATG
                     SIGIGLVIMRLLEHRPTDELVRTLHGIERTLVPPFAVQSNLFNGRAGFLLFADRLLQCP
                     WASISDEEVLARQARLLNLHALVRGTGIVFPGEQLMRLSCDWSSGSAGVLSVLRLYESR
                     HLKIVPPNLFRTPLLDRISVGHSGNEWRGASSELIMERR"
     PFAM_domain     10766..11338
                     /aSDomain="Pkinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00069.27"
                     /description="Protein kinase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1247_0176"
                     /evalue="6.80E-15"
                     /label="ctg1_1247"
                     /locus_tag="ctg1_1247"
                     /protein_end="446"
                     /protein_start="255"
                     /score="55.2"
                     /tool="antismash"
                     /translation="GGIYRAIPDGQEHPVVLKEARPHAGISPDGTDAVARLLREAEFLD
                     RLADLPEVVRCHRVFKAGEHCFMEEELIEGTTLNSEMVMRSPEIRAGVGNREILDYRDW
                     ALAALAKVERTVHAFHEHGIVFGDLHPNNIIVTPDGDIRFIDFEMAHDVDDPTSAPAGA
                     PGYIAEDGRTGIAADLYGLGCIKLSMFV"
     CDS             12737..12850
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1248"
                     /transl_table=11
                     /translation="MHGILVLQSLDTHSEPTRSPSNWSNWTCYSTRSIWFC"
     CDS_motif       12737..12802
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MHGILVLQSLDTHSEPTRSPSN"
                     /locus_tag="ctg1_1248_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12803..12850
                     /prepeptide="core"
                     /locus_tag="ctg1_1248_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="3.80"
                     /molecular_weight="1850.1"
                     /monoisotopic_mass="1848.8"
                     /core_sequence="WSNWTCYSTRSIWFC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MHGILVLQSLDTHSEPTRSPSN"
                     /leader_location="[12736:12802](+)"
                     /alternative_weights="1868.1"
                     /alternative_weights="1886.1"
                     /alternative_weights="1904.1"
     CDS             12880..12993
                     /locus_tag="ctg1_1249"
                     /transl_table=11
                     /translation="MSQILEMQGINSEEQDTRFPSTNSWAFCFSTHSVIVC"
     CDS             13287..13406
                     /locus_tag="ctg1_1250"
                     /transl_table=11
                     /translation="MSEVLRMQGLVEEARDMDRTITSSSSLALCGSSFSTWFC"
     CDS             13445..13582
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1251"
                     /transl_table=11
                     /translation="MQYILDLQRTETEPTGGMRTCNPVSFASCSLCSVSFASVAVCLTV
                     "
     CDS_motif       13445..13501
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MQYILDLQRTETEPTGGMR"
                     /locus_tag="ctg1_1251_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13502..13582
                     /prepeptide="core"
                     /locus_tag="ctg1_1251_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="7.50"
                     /molecular_weight="2451.9"
                     /monoisotopic_mass="2450.2"
                     /core_sequence="TCNPVSFASCSLCSVSFASVAVCLTV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQYILDLQRTETEPTGGMR"
                     /leader_location="[13444:13501](+)"
                     /alternative_weights="2469.9"
                     /alternative_weights="2487.9"
                     /alternative_weights="2505.9"
                     /alternative_weights="2523.9"
     CDS             13757..14860
                     /gene_functions="other (smcogs) SMCOG1238:transposase
                     (Score: 116.6; E-value: 2.3e-35)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1252"
                     /transl_table=11
                     /translation="VDFLCCFGYDWDMQVEVTGEETAVLIRWKKRADNYVLVRMKAEAI
                     LYASRGVDVSIIAEMVERSVKTIREWLAGWRDSRMCSVLTGHAGNQNAAKLTRAQKEDL
                     KAVLAQPPSQSGIDAEFWDVPAIRDVVKILFDVEYESDSSYQLLLRFCGLSFKLPDPFD
                     KHRDEQAVTRRMVEVKAQVKDLLDAGWEVYAADEVRLEHEAETRRMWLPKGQRTKLSVD
                     RKKTSQSFFGALSLTSKKVKLYPIEGNQNTEQTILALDRLQRETDTEKIAVVLDNARFH
                     HAKMLTGLYEPGQLLERITPIHLPPYAPDHNPVEHVRNAAKNNTANIQRETPEETFGAF
                     ASYITGRTFDYDFEHLPPRDTENDLVS"
     PFAM_domain     14330..14737
                     /aSDomain="DDE_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13358.8"
                     /description="DDE superfamily endonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1252_0177"
                     /evalue="1.70E-21"
                     /label="ctg1_1252"
                     /locus_tag="ctg1_1252"
                     /protein_end="327"
                     /protein_start="191"
                     /score="76.7"
                     /tool="antismash"
                     /translation="VYAADEVRLEHEAETRRMWLPKGQRTKLSVDRKKTSQSFFGALSL
                     TSKKVKLYPIEGNQNTEQTILALDRLQRETDTEKIAVVLDNARFHHAKMLTGLYEPGQL
                     LERITPIHLPPYAPDHNPVEHVRNAAKNNTAN"
     CDS             14927..16576
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 301.6; E-value:
                     1.9e-91)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1253"
                     /transl_table=11
                     /translation="VTAAGLSVVQPRVLQKTVNDGIQGGLQADTIELLAALVVGTTVIG
                     AVQAYLTGRGAEAVAHRLRTRLGRRYVSMTISELDAANTADLLSRANADSTMVKQFLSA
                     GILPVAGSVLMLAGTTVFMIMSDPILFAVTAAAFVLGLSLVIAVTNRANSMSAEVQEAL
                     GDFSVSTERMLSALRTIKATNAEPLELDHLRLSSHNLYRKGLRITVLSACVQPALNVCI
                     QGSIAAVIVVGTARLASGATTLGTLLAYITYMFMMIAPISSLGQAFTQMQIGLGALKRC
                     YEVDFFESEDDVRADHQTAIGTASGDELLRFDSVSFSYEPGTPVLTDVNFVLRRGETVT
                     IVGRSGSGKSTLLELIERFYHPDAGHISLGGVPIDQLDLNSYRRRLALVGQDSIVLTGT
                     LRENLELGCHRHPDSTLYEALEHVGLTDLLGKKDFGLDTDVGQAGITLSGGQRQRIAWA
                     RVLLSDADIILMDEPDSNLDPVTRSSLTHLLESFAATRTVLIVSHNLEHLNSSDRVLVM
                     DHGSILADGCRQELLATTSEYQDLLAPTQAAA"
     PFAM_domain     14933..15706
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1253_0178"
                     /evalue="8.50E-29"
                     /label="ctg1_1253"
                     /locus_tag="ctg1_1253"
                     /protein_end="260"
                     /protein_start="2"
                     /score="101.1"
                     /tool="antismash"
                     /translation="AAGLSVVQPRVLQKTVNDGIQGGLQADTIELLAALVVGTTVIGAV
                     QAYLTGRGAEAVAHRLRTRLGRRYVSMTISELDAANTADLLSRANADSTMVKQFLSAGI
                     LPVAGSVLMLAGTTVFMIMSDPILFAVTAAAFVLGLSLVIAVTNRANSMSAEVQEALGD
                     FSVSTERMLSALRTIKATNAEPLELDHLRLSSHNLYRKGLRITVLSACVQPALNVCIQG
                     SIAAVIVVGTARLASGATTLGTLLAYITYMFMMIAP"
     PFAM_domain     15902..16348
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1253_0179"
                     /evalue="1.20E-30"
                     /label="ctg1_1253"
                     /locus_tag="ctg1_1253"
                     /protein_end="474"
                     /protein_start="325"
                     /score="106.9"
                     /tool="antismash"
                     /translation="LTDVNFVLRRGETVTIVGRSGSGKSTLLELIERFYHPDAGHISLG
                     GVPIDQLDLNSYRRRLALVGQDSIVLTGTLRENLELGCHRHPDSTLYEALEHVGLTDLL
                     GKKDFGLDTDVGQAGITLSGGQRQRIAWARVLLSDADIILMDEPD"
     CDS             16590..17330
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 154.9; E-value:
                     4.6e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1254"
                     /transl_table=11
                     /translation="MTTGTSTIPSTRPSDPAPISFEHVTKSYESRLILDDVSFSIESGA
                     VTGLLGPNGSGKTTMLRCLLGLASPDSGICLVEGNRYDAIPVPSRLVGALCENAGLHPN
                     RRAAECVALARAAAGLTDPHAVDAHLEQVGLADAGPMRVREMSLGMRQRLSLALALVGD
                     PHVLVLDEPSNGLDPEGMEWFRTLLRRFAASGGSVLITSHILAELQRTIDAVVIVRGGR
                     VVAQSDTLPDDLDSFYLATSGNRG"
     PFAM_domain     16689..17111
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1254_0180"
                     /evalue="1.90E-25"
                     /label="ctg1_1254"
                     /locus_tag="ctg1_1254"
                     /protein_end="174"
                     /protein_start="33"
                     /score="90.1"
                     /tool="antismash"
                     /translation="LDDVSFSIESGAVTGLLGPNGSGKTTMLRCLLGLASPDSGICLVE
                     GNRYDAIPVPSRLVGALCENAGLHPNRRAAECVALARAAAGLTDPHAVDAHLEQVGLAD
                     AGPMRVREMSLGMRQRLSLALALVGDPHVLVLDEPSN"
     CDS             17327..18169
                     /locus_tag="ctg1_1255"
                     /transl_table=11
                     /translation="MSTMNVEIMRLRQGRIASTMTIILIIATFLVATLEAFARDTINAL
                     ISLNRVIPNATQAQSMSPEDLAKLSLDQPGLQLTAAANAGGVGGVSPAALAMMIMGGLF
                     ITREYHFASMTSAAVALPRRGQLYRNKCAAAALASFVAAFGLTAVRLLVLFTALAVQRI
                     NLALDPFALVMSELRGLVTLVLCGVLGAGLGFLLRRQTVLLLLLGGLFVVESTFRSLAT
                     LTGADILHGCLPLSATGLSTQPGAQGWLAAGIVVAWSAIVVTWGAFCFNRRELTFSAL"
     CDS             18203..19405
                     /gene_functions="regulatory (smcogs) SMCOG1048:sensor
                     histidine kinase (Score: 160.8; E-value: 9.1e-49)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1256"
                     /transl_table=11
                     /translation="MSRGAAERVNQQLRQTVLASFLVSLLNVLLVANSENSLAQILWQI
                     GLTVLGVVCTIILINRPVVAFAIVHTAVLVAALTQQNPFVTQFLLYLPLCFWLGRRTRS
                     RTSSVTAMIGLTTTIGAFVLAPVRTGSDGIALLAPVGFVSGSLFIGAPTLVGAWMRIAN
                     ERAVGVETLLKAERAESEARIAKALEDERGLMARELHDIASHHMTAVLLDARLARRMLP
                     GNPQRAAELLEELTREAGSASESLHEVVGILAAGSQAPTAPQPTLADIPELLRRARAIN
                     PDIGVAMPQDPKVSPAVGLALYRIVQESLTNAHRYAPGAPIMVDLTIKNGWMSLSVTNG
                     LATQPTSGISGSGLGIQGMRMRCELLGGTLTAGPHEGGWAVRARLPQRAGEDGPTALAG
                     T"
     PFAM_domain     18773..18961
                     /aSDomain="HisKA_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07730.15"
                     /description="Histidine kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1256_0181"
                     /evalue="2.50E-09"
                     /label="ctg1_1256"
                     /locus_tag="ctg1_1256"
                     /protein_end="253"
                     /protein_start="190"
                     /score="37.6"
                     /tool="antismash"
                     /translation="ERGLMARELHDIASHHMTAVLLDARLARRMLPGNPQRAAELLEEL
                     TREAGSASESLHEVVGIL"
     CDS             19490..20122
                     /locus_tag="ctg1_1257"
                     /transl_table=11
                     /translation="MNIRSHSSQPVIGYIIVVIALAGMICYSLLFWDDMPAQVITRQAA
                     GRHGASAVPRGVSAAAMPATLLVCTLLLMLMPLWNRLVGSTPLRPGPDQRQQTRIWTAI
                     LAMLSALLLTLHIGITDMCTGRGPQFPQLAAYGMAVTLIGLAAITAILRVRAHRAIVMG
                     LALGGALVAALAHGLPRAAMTVGTVIMLGGIAAATLLPQLRNDGGRR"
     CDS             20388..22004
                     /locus_tag="ctg1_1258"
                     /transl_table=11
                     /translation="MFRSPVRRDGPRWRSFVPVSTRVYVASPDARADLSAAAQAIAEAA
                     GRQSSPAVLFHPLAAQASSARLVGASFDEFARSTDEAETGIIERFEALAAAGPVVAVGT
                     DYSGVTAPTELALNGRLAADLAAPVVLVVDASQGPDHALGLARVALDGLAAQHATVVAI
                     IATGPTHTDATRTLLASLGVPAAVLGDDLSAVLAATDVTITTRTPARFSHELMATARAD
                     VRTIVLPESEDPRILEAASVVAARGVARIVLLGEEEQVRADAKRQGLDLTGVEIVSMNN
                     PGLVESYAAKFAELRAKKGVTLEQAREAMADGACFGTMMVYMGGADGLVSGANHTTANT
                     IRPALQVIKTNPGMKTVSGAFLMSLADRVLLFADCAVTPNPEPAQLADIALASAQTARM
                     FGIDPKVAMLTYSTGTSGSGPDVDRVRAGYEEAVQRAPEERIAGPIQFDAAIDPVVGAK
                     KMPDSEVAGRATVFVFPDLEAGNIGYKICQRTAGAVAVGPLLQGLRRPVNDLSRGALVD
                     DIVNTIIMTAIQAQGTNGPLA"
     PFAM_domain     20601..20939
                     /aSDomain="AAA_26"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13500.8"
                     /description="AAA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1258_0182"
                     /evalue="2.60E-06"
                     /label="ctg1_1258"
                     /locus_tag="ctg1_1258"
                     /protein_end="184"
                     /protein_start="71"
                     /score="27.5"
                     /tool="antismash"
                     /translation="FDEFARSTDEAETGIIERFEALAAAGPVVAVGTDYSGVTAPTELA
                     LNGRLAADLAAPVVLVVDASQGPDHALGLARVALDGLAAQHATVVAIIATGPTHTDATR
                     TLLASLGVP"
     PFAM_domain     21018..21968
                     /aSDomain="PTA_PTB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01515.21"
                     /description="Phosphate acetyl/butaryl transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1258_0183"
                     /evalue="1.60E-121"
                     /label="ctg1_1258"
                     /locus_tag="ctg1_1258"
                     /protein_end="527"
                     /protein_start="210"
                     /score="405.6"
                     /tool="antismash"
                     /translation="FSHELMATARADVRTIVLPESEDPRILEAASVVAARGVARIVLLG
                     EEEQVRADAKRQGLDLTGVEIVSMNNPGLVESYAAKFAELRAKKGVTLEQAREAMADGA
                     CFGTMMVYMGGADGLVSGANHTTANTIRPALQVIKTNPGMKTVSGAFLMSLADRVLLFA
                     DCAVTPNPEPAQLADIALASAQTARMFGIDPKVAMLTYSTGTSGSGPDVDRVRAGYEEA
                     VQRAPEERIAGPIQFDAAIDPVVGAKKMPDSEVAGRATVFVFPDLEAGNIGYKICQRTA
                     GAVAVGPLLQGLRRPVNDLSRGALVDDIVNTIIMTA"
     aSDomain        21063..21968
                     /aSDomain="TIGR00651"
                     /aSTool="tigrfam"
                     /description="pta: phosphate acetyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1258_0020"
                     /evalue="2.40E-115"
                     /identifier="TIGR00651"
                     /label="ctg1_1258"
                     /locus_tag="ctg1_1258"
                     /protein_end="527"
                     /protein_start="225"
                     /score="383.2"
                     /tool="antismash"
                     /translation="IVLPESEDPRILEAASVVAARGVARIVLLGEEEQVRADAKRQGLD
                     LTGVEIVSMNNPGLVESYAAKFAELRAKKGVTLEQAREAMADGACFGTMMVYMGGADGL
                     VSGANHTTANTIRPALQVIKTNPGMKTVSGAFLMSLADRVLLFADCAVTPNPEPAQLAD
                     IALASAQTARMFGIDPKVAMLTYSTGTSGSGPDVDRVRAGYEEAVQRAPEERIAGPIQF
                     DAAIDPVVGAKKMPDSEVAGRATVFVFPDLEAGNIGYKICQRTAGAVAVGPLLQGLRRP
                     VNDLSRGALVDDIVNTIIMTA"
ORIGIN
        1 ggcgccgagg cagatgccga gggtggggcg ccgcccgacg aggcgctgga ggatcgcgcg
       61 ccgctcgtcc acgagccacg ggtaggcgtc ggtctcgccg gcgcccaccg gaccgccgag
      121 gacgaccgcg atgtcggcgt cgtcgagcgc cgacagctcg tccaccccgc cctggagcat
      181 cgtgaccgag tggccccggg cgcgcagcac cggttcgagg acgccgagat cctcgaaggc
      241 gacgtggcgg acggcgacga ctgtacccat ggctgcatcc tcgcacggga tgcgcgcccg
      301 cggcgcgtgc gcatcccgcg gccccggcgc cgatgcgcag ccgcccgccc ttcatgaccc
      361 gcccgacgct gccgggccgc cagcgcgtgt gcgggttgaa ggcgatgagc ggggccgccc
      421 cggtcatgcc gtagccgtcg aggatgtgga ggccggccgc gccggagaac ggctggacct
      481 cgcgcgacag cggggcgccg ccgctcacga gcatcctctc cggcccgccg atcgcggccc
      541 ggatcccgcc caggacgagc cggtcggcca cgaggagccg cagacggtcg cgcagcgggg
      601 ccgctcgccc cggttgtacg cggcctgcac ggcggcgacg acgccgagcg accagtcgac
      661 gaggcgcctg cgcggccccg agtcgccggc ctcggcgcgg gcgccggcca tcgccgcctc
      721 gtagagctcg gggacggcga ccatcatcgt cgggcgcgcc agcgccatca tctcggcgat
      781 gcgccgggtg ttcggtgacg taggtgctca tgcagccgtg cgaccccaga tgggcggacc
      841 aggcgcgttc gagggcgtgc gagagcgtcg ggaggcacag cgagcgctcg gcggggccgg
      901 aggagagcat ctcgtcgagg gcgcgggacc cggcgatcat cgcgcggtgg gcgatcatga
      961 cgcccgtggg ctcgccggtg gtgcccgagg cgcagatgat gctgtatcag gtcgtcgccg
     1021 gtggccgcgg ccagtcgggc gtccacctct gcggccagcc cctcgtcgag cgggccgtcg
     1081 acgggggcga agccgtcgag gctctcggcg ccctcgtcca gctcgcggta ggtggcgacg
     1141 tcccaggccg ggggtcgtcg ccgaccagca cgcgggtggc cgggcggtgg ctccggcggg
     1201 aggccgcggc cttgaactcg aacatgaggg cgacgtcgtc ccgggcatgg ggtggagggg
     1261 ccggaggtgg gacgcgtcag atcctcgctc gcagccaggc gatgtcggcg gcctgggcct
     1321 cggccccgcc gggggtctcg acgacggcgg gtgccccggc cgtggcgacg atgcgtgcga
     1381 tggcctcggc gtcggccagg ccctggccga gattggcgtg ccggtcggcg ccggttccgg
     1441 gctcgtcgcg cgagtcgttg gcgtgcacga ggtcgatgcg tccggtgatg gcccgcaccc
     1501 ggtcgacgag gccgtcgagg ccgaggcctg ccccgtgggc gtggcaggtg tcgaggcaga
     1561 agccgacccg gtccccccca tcgaccgccg cgagcgccgt ccacagccgg tcgatcgact
     1621 cgagccggcg ggccatggcg tgccggccgc ccgcggtgtt ctcgatgagg atcggcaccg
     1681 cggcgtcgag cccggccacg gccttcgccc agttctcgta cccggccccg gggtcgtcct
     1741 cggcggtgac gtgcccgccg tggacgacga ccccgagcgc gccgagttcg gccgccatgt
     1801 cgacgtgctt ctggagcagt cggcggctcg gcacgcggat gcggttgttg gtgctggcca
     1861 cgttgatgac gaagggcgcg tggacgacga gcgccagccc agcgtcggcg gccgcgcgcc
     1921 gcagcgcctg cgggccgccc ccgtgggcga ggacggggcc cttccagctc cgcggatcgc
     1981 cgaggctgat ctggacgatg tcggcgccgc gcgccgcggc ctcgccgacg gggtcctcct
     2041 cgtcgacgtg ggcaccgatc aggactgaca tacggtgagc ctagtgggcg cccggggcgg
     2101 cgccccgacc ggccccgccg ggacccgcga gcgctcgccg cgaacggtca aaggccccgc
     2161 gagcattcgc cgcgagcggc tccggaaagc ccgcgagcgc gggcgacgga cgcccggacg
     2221 cccacggcga acggcccgcg cctgctgcgg cgacccggtc cggacccttc gcccgggccc
     2281 ggtgcgcgcg cctagactgg acaggatgaa cgcccacctc gaccacgatc cggccgcatc
     2341 ggcgccactg cgctggctgg cccgtttgga cgacgaggtc ctcctcaacc actacccgca
     2401 gcgctccgtc gagcggggcg ccgcctacgc cgaacgctcc ggcgtcgtca ccgacgtgcg
     2461 gctggggccc gacgccctct cggggcacgt gcagggcacc ctgtcgtccc cgtacgacac
     2521 ctcgatccgc ttcatctgcg cgggccggcg cgtcatcacc tggtcggact cgtgcacctg
     2581 ccccaagggc agggactgca agcacgccgt cgcgctgctc atgagcgccc gctcggccgc
     2641 gcagctcgtc ctcgagggcc gcgccgcggc ctcggcgccc gcgccgacca gctcgtggga
     2701 gcgcgtgatg gcccggctcg cccccgagca gggcggcacg cgcaagctcg ccgtcgtctt
     2761 cgaggacgcc ggcatcgccg ggtacgacta cgtctcctcc ggccgctggc ggctgcacct
     2821 gctgcgcacc ggcgtggacg gggactgggt cggcaagcgc gtgcgctggc gcgatctcgt
     2881 cgaggccccg gcgatggtcc aggcccgctc cgaccagcgg gccgccgtcg tggggctggc
     2941 gcagctgctg ggctccgggg acgcccacgc ggcgaaccgc gtgacgctcg agtcgctgcc
     3001 ctccgaggtc tgggcgcagc tgcgccgggc cgtcgacgcg ggggtcgagc tgctgcacga
     3061 cctgggcgac cgccggcacg cccgcgtcca cctggacccg acgaaggcct ccctcggcct
     3121 gaacctcgcg gcggccggcg acgactacga gctgcaggtg ctgctgagcc gcgacgggcg
     3181 ccccgagccg ttccgccccg gctggacgct gctgggcgag ccggcccacg gcatcctgcg
     3241 caccgagcct cgcggcgagc tgcggctgac cgagctcgac cgctccgtcg acccggccct
     3301 gcggcccctg ctcgaggcgg cgccctcgct ggcgctgccc gccgacgatc tgccgcgctt
     3361 cctcggcctg tacgccccgc agctgcgcag caacctgcgt ctgacgagca gcgacgcgcg
     3421 ggtcgacatc gacgcgccgc cgaccggggg cctgtgggtg cagctcgact tcagccggcc
     3481 cggacggctg gcgctgcgca gcggggtcgc cctcgcctcg gccggccaca gcaccaggct
     3541 cgagcttgag cgctgccccg ccgggctcat ggacgagggg gcgcggctcc tcctggaccg
     3601 ggtccgcgat ctcgtcgggg ggcagaccgc cgagctgacc gggcgcgccc tcctcgactt
     3661 cgtcacccgc gagctgcccg ctctggagga cgacccgcac gtgctcgtcg aatgcatcgg
     3721 cgtccgtccc gagtacaccg agctcaccgg cgaaccgagg ctcgccgtcg aggtcctcga
     3781 cgccgagccc gacgccgatg acgcggccct cgccacctcg gcggtggagg acgccgccct
     3841 ggacggctcg accgactggt tcggcctgtc ggtcgtcgtg acgatcgacg gccgggagct
     3901 gccagtggcg gcgctgctgg ccgccctgac cgccggcgac gaccacgtca tgctcgacga
     3961 cggcgcctgg atcgacctcg cccgtcccgg gctcgatccg ctgcgtcgtc tcgtcgagga
     4021 ggcggcgcgg ctcgtcgacc cggggacggg cgagatgcgc ctgagccgct gggacctggg
     4081 gacctggcag gacctggagg cctcgggcgc catcacggcc gcctcggccc gctggcggcg
     4141 ctcggtcgcc gcgctcgggc acctggacga gatcgccccg cccgacgtgc cggcggcgat
     4201 cggggcccgg ctgcgcccct accagacgga gggctaccag tggctcgccg cgctgtggac
     4261 ggcggggctg ggcggcatcc tcgccgacga catgggcctg ggcaagacgc tgcagaccct
     4321 ggcgctcatc gcgcgggccc gtgagaccgg ggagctcgcg cgcccggcgc tcgtcgtcgc
     4381 ccccacctcc gtcatggcgg cctggacggg cgaggcccgc aagttcgcgc cctcgctgcg
     4441 ggtcgtcgtc atcgaccaga cggccaccaa gtcgggcgtg ccgctggccc gggccgtcgc
     4501 cggcgccgac gtcgtcgtgg cctcgtacac gctcgtacgg ctggacgagg cgagcttcac
     4561 cgcgctggag tggagcctgc tcgtgctcga cgaggcgcag ttcgtgaaga accacacggc
     4621 caagacctac gccgtcgtga ggcgcctgct ggcgcgcatg cggctcgtca tcaccggcac
     4681 gccgctggag aactccctca tggatctgtg gagtctgctg tcgatcgccg cgcccggcct
     4741 gttccccgac ccgaggcgct tccaggccga catcgcccgt ccgatcgaat cgggcgacga
     4801 gccggaccgg ctcgccctgc tgcaccggcg cacccgcccg ctcatgctgc gccgcaccaa
     4861 ggagcaggtg gccgccgaac tgccgcccaa gcaggagttc gtcgtgccgg tgacgctggg
     4921 gcgggcccac cgccgcatct acgaccgtga gctggccgcc acccgcatgc gcgtgctggg
     4981 gctgctcgac gacagctccc gcacgcaccg catcgagatc ctcgccgccc tcacgaggct
     5041 gcgccagctc agcctgcacc cgggcctgct cgacgaggcg gacctggccg tcggctccga
     5101 gaagatcgac tcgctcgccg agcagctcca ctcgttggcc caggccgggc accgggcgct
     5161 cgtgttcagc cagttcacgg gcttcctcaa gctggtgcgc gagcgcctca ccgccgagcg
     5221 gatcggctgg gagtacctcg acgggcgcac ccgccgccgc gaggagcggg tgcgggcctt
     5281 caaggagggc gacgccacgg cgttcctcat ctcgctcaag gcgggcggtt tcggcctcac
     5341 gctcaccgag gccgactacg tcttcgtcct cgacccgtgg tggaacccgg ccgccgagcg
     5401 ccaggccatc gaccgcaccc accgcatcgg ccaggacaag caggtgatgg tctaccgcct
     5461 cgtgtcggcc gacaccatcg aggagaaggt cgtggagctg cagcagcgca agcgcgagct
     5521 gttcgaccag gtcgtcggcg acgaggcgct gagcagcggc gccctgaccc tggacgacat
     5581 ccgcgggctg ctggcctgag gcggggccat ggggcccggt gccgtccggg accggggccc
     5641 accggcccgg ccccgcaccg cccctccggc ctggtcccgg ccccgcaccc ggcttcgctg
     5701 ccgcccctcc gttcccacct caccttccgt tcccacctca ccttccgttc ccaccgcact
     5761 cttcggtcaa caccctggac atgtacgagg tgcgaacgca aaggcgaagt gggaaccgga
     5821 gaagaggcgg gagaagcgag gagcggccga gtcccgagcc catctcccgg ccttgggggc
     5881 tcagccccca ggggtggtgc gctccccagg ggtggtgcgc cccggggcga cgtcctccgg
     5941 ggcgtcctcg gggtcgacga ggcgcgcggt caggccatgg atgccgagga tcgtgacggg
     6001 caggccgacg agcgccgtcg tgatcgtcct gccgtcgaga cgcagcaccc cgttgcgcgc
     6061 cagctcccgg acggcccagg ccgagaacgg gatgacgacg gtcggcgcgg tggcgactcc
     6121 gggcgtgtag ccgcgccgca cggccgaatt gagcagatgg gtgaagccgt ggacgccgaa
     6181 accgagcagg cccacctgat agagccggga cctgcccccg gtcgccctgc cccgctcggc
     6241 gagggcgagc atgaggcatc ccatgatcga tatcgacacg cggacgtgcc tctcgctcag
     6301 cccgccgctc acccgtcggg gggccccgcc cggcagtcgc cctgcgagtc tgctcgcgag
     6361 ctcggagccg tgcctcctcg accacggccc catggtggtc agttcctcga ggtcgttggc
     6421 gacccaggcc cagaacaggc cccgggtcgc ctcgacggga accccctggc caccgcggtc
     6481 gccgttcccg ttccgatgtc cgaacatcat gatatactcc cttgtcatcg tgcatttaca
     6541 ggttctccat gtcatcggcc gccctggtgg gccccacgcc gggcccctcg atcacctcct
     6601 cggagaggag ccactatgcc cgcgcgcgtc ggtccaccgc cgcacgacga cggtccggga
     6661 cgagtcatgg cgcaccgggt cgaggctctc ttccaacccg ggacctcgtc ctccgtgccc
     6721 gaactgcccc tggggatcgc gggccggatg ggcagcggga agagcaccat gatgaggacc
     6781 atcgcggcga tggcggcccg ttcgggcacg gtcgtgcgct gggtcagcgt gacggattcg
     6841 gaccccggca tccgccggtc aggtcaacgc cgagctgatc ggcgatccat gcgtactgga
     6901 cagccgtgtc gtgaaccgtc gcatcgaatg atgcagcatg cagttggccg ccggaacgaa
     6961 cacgcagtac gaagggcccg cccctcgcag tggtgcgcag cgcacggatc catttgaggg
     7021 cctccagcgg agaaacccgc gcgtccctcg tcctgaccgt ggcaagcacc gggggtaaac
     7081 cgcgtcacgc acgttctggc acggtgaata tccgcggatg cactcgaaga tcctcggatc
     7141 ggccaacggg tccccccact ccgagcgatc gctgatcgtc aatggaagat ccgggtgcat
     7201 catcgttgtc agcggatcga caaaaggcat gtcggcgacc accgccctga accgttccgg
     7261 cgcaagattg aggaccgccc ccacagccag gcctccagcg ctgccgccga tgagggcaac
     7321 acgattcgga tcagccgttc gtcgtgcgac aagggcgtcc aagcacgcca gcacgtcggt
     7381 gaaggtgagt ggtttcccca ggccggtcgc caccgtgtgc caccgggggc cgagctcacc
     7441 tccaccgcgt acatgggcaa ccgcgaagac catgcctgcg tcgagcagct tgagaagcag
     7501 cggattgtag ttggggcgct gattcacccc gtatgcacca tagacactga gcaggcaggg
     7561 agcgggaccg gtgcgatctc gccgaccgac aagagtaatg gggatccgaa cgccatcagc
     7621 agtctcgccg aaaagttcct tcgtctcgta gacatcctcg ttgagcgcag ccagctcgac
     7681 cctcggctcg gtttcgtcca ggtcgaccct gccactcagg ggccggtgca cataggagct
     7741 gacgcccact ctgagaaccg agccatccca gtcgggcagg gccgtgacgc tcaattccga
     7801 accagtggcg ccacgcaccg aacggatgcc cgtcaacgga actgtcggct tggcgatgac
     7861 gatcccctgg tgcccctccc tgcggcgccc gatgacgaga ttgcgacgag tcaccagcac
     7921 cggagccagc acggaacgct cgtcatgctc gatgagacac ctccagtccc cctctgcgcc
     7981 gccgaggcgg tcgatgaagc ggaccagcag acggccattc ggttgatcat ccgtggcgac
     8041 tgtggcgaac agggccggac gcccgtccag ctctccgaca tcgagggtcg accgtccctc
     8101 gaatggcagg cccgcaacct gtcgaagtcg aagatcggca gcgcccaggc gggagatgaa
     8161 gtgtcgcacc atggtcctgc tcaccgcatc cagcaagagg aaatctcccg agacgcactg
     8221 cttcattcgt agcctcagac gctcatcgca ctcgtggtgc aacacagtga cccggccatc
     8281 agaaaaactc ttggcgaaga cggccgcagg ccggcgtgtc ccgtcgagcc cgacccacac
     8341 gacccgcgac cctttttcat cgaggacgac actgccagaa caaccgtcga tcgggtcaag
     8401 aagctccttc tgaccggcga ccgaggtcac atggaccctg taggattccg aaccatccgg
     8461 gtcctccgtc cagcagacga tcctgccatc actgctgaac acgactgatc cgagtgaagc
     8521 cccgggtgcc aattccgcga cattgagcgc cacctgcgca cgtggatctg acatgagatc
     8581 cgtggccgtc ggctccggct cgtcggaatc atgaggcact cgcattatgc tgggactgcc
     8641 ggcctccccg tcgagcacca tgagatacca gaagtcccct gatcgcaccg cgggctgcga
     8701 agcttgttcg tagaacagat cagcaacggg aacacccacg agcgcatcag cccttcgggc
     8761 aggcccggca aggacccgct cgctgcactc ggcctcgtcc tcgagcaccc gctgcaactc
     8821 atctgggctg ttcctgagcc actcccactg atcggtccag ctgcggacat gcgaaatggt
     8881 cgccatcggc ccggctccgt tcatcattca tcctccgccg agaagaccaa ctgcctgtca
     8941 tgcgcccaga tggcgatctg gacccggttg ttcatgtcga gccggttgaa tatcgacccg
     9001 atatgtgctt tcaccgtcgt cacctccaag tggagacgac gcgcaatctg ttgattgctc
     9061 aatccgtccg agatgagagc agccacttga cgctcccgca cggtgagcag ttccggagcg
     9121 gcccccgccg tcggaacggg caccggcttg cggttcgcga actcggccgc cagccgagca
     9181 gccaaccgtg gtttcagcca gcagccgcct cgggcgaccg tacggatcgc ctcggacaga
     9241 tcatcgagat cgagatcctt gttggcgaat ccagaagcac cgagatccat ggcgacgaac
     9301 aggtactcgt cacgttcgaa ggtggtcagg atcaggatct tggatcggtc agactcggcc
     9361 aggatctgcc gtgtagcctc caacccgttg cccttcggca tccgcagatc catgaggatc
     9421 acatcgggtc gccatgcgtg cgccagagag acggcctcgt aaccggtgga ggcctcggcc
     9481 acgacctcga tgtcgggact ctcgccgagg aaatcccgca gtccacggcg gatgatcgcc
     9541 tggtcatccg cgatcaggac agtgaccgta ccggggtcct cgggatcggg ggcgtcgatg
     9601 cctgccgatt catcttgctg catggtccct cctgggatca gcccgtccac caggacgggg
     9661 gtgggcctcg gcacgaggct gtggcgccat ccacgatagc cccggggacc cccgtcggga
     9721 accccgagaa gttcgcccgg gacacgggcg gggcggagaa cccgacacag gataacgggg
     9781 gccgctcccc cgctcggtat ccgtcgcggt cgacatctgc cgcaaggttc acctgcgccg
     9841 gcggcggcta ctcctttggt ccagtcccgc actcgtacct tggtcgtcac agatctggac
     9901 caagcgggcg gcagccatca caatcgaatc accccatcaa gggatcgcgc gttggatgcg
     9961 ggatcgaacc aggacacaac aagcgagcga gaactccacc atggggattc cacaagtcat
    10021 gactattcca atggagacag acccgatgga catgaaatat ctcgcgttct gctacgccga
    10081 cccggcgttc tacgacatca aacgcgacac gacgaatggt tcgggagcgc gacggttcga
    10141 acttccccgc gaccgcgact ggaccagctg gtcgctgtcc acggggaatg gctgggaata
    10201 tgtgatgcca cctgggatga acatgcctga gcagggctgg aagattcacg tcagtgccac
    10261 catggaaaac gcgcagaaac tccttggaga cgtcgcatcc tactgccatg cgtctgccgt
    10321 cccgttcaag ttcctgccga cccggacgga gctcatgcgg accaacatga agtacgcgca
    10381 tcgtggcagc agcggaaaat tcatcaccat ttatcccgat gacgatgagc agtgcgctcg
    10441 cattgccgca gaactggacg cgatcatcgg cggcgccgag gggccctaca tcctcagcga
    10501 catccgttac catggaggcc ctgtctacct gcgttacggc ggcttccgtc cgctgctcat
    10561 gagatcacgc accgacgagc tgagcccagc gatcaggaat ccgtcaggag aactggtcga
    10621 agacgatcgc cagccggtct tccgtccgcc ggaatgggtg cagatccctg atttcatccg
    10681 agcacagatg gacgctctga attctggtga ccgacccgaa gagttcccct atgcagtact
    10741 cgacgcgatg cacttcagca acgggggcgg aatttatcgg gccatccccg acggccagga
    10801 gcatccggtc gtgctgaagg aggcccgccc ccatgcaggc atctcgccgg atggcaccga
    10861 tgcggtggca cgtctgctcc gtgaagcaga gttcctcgac cggttggccg acctccctga
    10921 agtcgtcaga tgccaccgtg tgttcaaagc gggcgagcac tgcttcatgg aggaggaact
    10981 gatcgagggc acgaccctca acagcgaaat ggtcatgcgc agcccagaga tccgggcagg
    11041 agtcggcaat cgagaaatac ttgactaccg cgactgggcg ctggccgccc ttgcgaaggt
    11101 cgagcgaaca gtccacgctt ttcacgagca tggaatcgtc ttcggggacc tgcacccgaa
    11161 caacatcatc gtcacccccg atggggacat ccgcttcatc gacttcgaga tggcccatga
    11221 cgtcgacgac ccgaccagcg cgcccgccgg ggcacctggg tacatcgccg aggacggccg
    11281 cacaggaatt gcagctgatc tctacgggtt gggctgcatc aaactgtcga tgttcgtacc
    11341 actcacggtc ctcctgccgc tggatcacag caagttgcga ggtctggtcg aacatgccag
    11401 acaattttat gcattgagtg atgagttctg cgcctcgatc gtcgccgaca tctcactgac
    11461 agtgaccgat gacaatccgg caccgctgcg acgacgcgca cgggtggcac gggacgcatg
    11521 gtgcatggat gatcccgaag cagttgctga gatcgatgcc gcgatcgtcc gcggcctgga
    11581 cgaagcactc gacctgtcac ggcccgaccg tgtctggccc ggtgacgtga gccagttcga
    11641 cgagggcggc tacgggatcg caacaggggc atgcggtgtt ctcctggcgc accctgaggc
    11701 acggcagcgg gaggacgtgc tcgattggat cgaggaaacc gcggccgact cgagcaagac
    11761 ctcgttcggc ttctacaacg gtcttgctgg agctgcatgg acactcgacc gtctcggcag
    11821 aggagaagcg gctgacaggc tttttgaaaa ggtcaggaca cttcatctgc caagtcttcc
    11881 cagtgatctt tactcaggac tgtccgggat cggcatctgc ctcatggacc aggcccgcag
    11941 acacaaccag caccactacg acgagaccat cgccgccatt cacgaggtga tgctcgaccg
    12001 ctttgacgag gaccgctcaa gcattgtccg agaggtcaat ggcacagcga cagccgcagt
    12061 gggcaagggc ggactgatgc aggggatggc cggtcaggcc ctgtactgga tctgcagtca
    12121 tgaattcacg ggcgacgaca ccgatcctga tcgggcgagc accgccctgg acagggacct
    12181 cgccctgctg gtccagacac ctgacggctc cctgcagctg aacgagggct ggcgagtgct
    12241 gccctatctg gcaactggat ccatcggcat cggtctggtg atcatgcgcc tgctcgagca
    12301 caggcccacc gatgaactcg tgagaacgct tcacggcatt gaacggacgc tcgtcccgcc
    12361 cttcgcggtg cagagcaatc tgttcaacgg ccgcgccggc tttcttctct tcgcggaccg
    12421 cctgctccag tgcccgtggg catcgatcag cgacgaagag gtcctggcgc gtcaagcccg
    12481 actgctgaac ctgcatgccc tggtacgtgg caccggaatc gtctttccag gagaacagct
    12541 catgcggctc tcgtgtgact ggtcctccgg gagcgcaggc gtcctgtccg tcctccgact
    12601 gtacgagagc cgccacctca agatcgtccc tcccaatctg ttccgcaccc cactgctgga
    12661 ccggatcagc gtgggtcaca gcggaaatga atggcgggga gcatcgtcag agctcatcat
    12721 ggaaaggagg tgaaccatgc acggaatcct cgttctgcag tcgctcgaca cacattccga
    12781 gcctacccgc agcccgagca actggtccaa ctggacatgc tacagcaccc gcagcatctg
    12841 gttctgctga agagcgccaa cacgaaaaga ggatgaacca tgtcacaaat tctggaaatg
    12901 cagggaatca attccgagga gcaggacacc agattcccca gcaccaacag ctgggcgttc
    12961 tgcttcagta cgcacagtgt catcgtctgc tgaccaccac aaaccatttc aaaggagaaa
    13021 tcatgtcata catcctgtca cttcagggtt cggaatcgac cgatcgcacc actcgcatgt
    13081 gcagctcatg gagcctcgtc ggatgtgcaa gcacttggag cgccgccatc tgctgacacg
    13141 catcggcgtc aaggggccct tgaagccgaa gaatcaacgc gaatcatgca tcggatgcag
    13201 aacaatgaca ggcggcagtc cgccgttctg cgcgagcaga ctcagaatca atcacctgcc
    13261 agacacctgg cggcaaggag ctcatcatgt cggaagtcct gagaatgcag ggcctcgtcg
    13321 aggaggccag agacatggac cgcacgatca ccagcagcag cagtctggcg ctctgcggaa
    13381 gttcgttcag cacctggttc tgctgaacga atcctcaaag cctcacgagt agaaaggaca
    13441 tctcatgcag tacatactgg atctgcaacg aaccgagacc gaacccaccg gtggaatgcg
    13501 aacctgcaat cccgtcagtt tcgccagctg ttccctctgt tcggtgagtt tcgcctccgt
    13561 ggccgtctgc ctgaccgttt gacggtctga ccacccgttc accgccagtg gctgtgggga
    13621 acgtcgctgt tccccgcagc cacttggaga aaggaaaaca gtccctcatg tctgagaacg
    13681 cagcaagacg ccacccggag gaccttccgt ccagcatgcg cagctatggc cgtcatgaaa
    13741 cgaaaccgta tttttcgtgg atttcctgtg ctgtttcgga tatgattggg acatgcaggt
    13801 tgaggtcacc ggggaagaaa ccgccgtcct gatcaggtgg aagaagcgcg cggacaatta
    13861 tgtgttggtg cggatgaaag cagaagcgat cctgtacgct tctcgaggcg ttgatgtgag
    13921 catcatcgct gaaatggttg agcgcagcgt gaaaaccatc cgggagtggc tggccggttg
    13981 gcgggacagc aggatgtgct cggtgctgac cgggcatgcg gggaaccaga acgcggcgaa
    14041 actcacccgt gcccagaagg aagacctcaa ggccgtcttg gcccagccgc cctcacagtc
    14101 cgggattgat gccgagttct gggacgtccc agcgatacgt gacgtcgtga agatcctgtt
    14161 cgatgtcgag tacgagtcag attcttcgta ccagctgctc ctgcggttct gcgggctgag
    14221 tttcaagctg ccggacccgt tcgacaagca ccgcgacgag caggccgtca ccaggcgcat
    14281 ggtcgaggtg aaagcccagg tcaaggacct gttggacgcc ggttgggagg tgtacgcggc
    14341 agacgaggtg cgcctggagc atgaggccga gacccgccgc atgtggctcc cgaaaggaca
    14401 gcgcaccaaa ctgtccgtgg accggaagaa gacgtcccag tcgttcttcg gtgctctctc
    14461 gttgaccagc aagaaggtca agttgtatcc gatcgagggg aaccagaaca ccgagcagac
    14521 aatcctcgcg ctggaccgac ttcaacgcga aaccgacacc gagaagatcg cggtcgtcct
    14581 cgacaacgcc cggttccacc acgccaagat gctgaccggt ctctacgagc ccggtcaact
    14641 gctggaacgc atcaccccga tccatctgcc accgtacgcg cccgaccaca acccggtcga
    14701 gcacgtccgg aacgcggcca agaacaacac cgcgaacatc cagcgcgaga cccccgaaga
    14761 aaccttcggc gcattcgcct catacatcac cggccgcacc ttcgactacg acttcgaaca
    14821 cctcccaccc cgcgacaccg aaaacgatct tgtttcatga ccgccatacc tcgtcggact
    14881 caccagggga agtcgcatca ccctcggtac cgccttggtc ctgtcggtga ccgcagctgg
    14941 tctgtccgtc gtccagcccc gcgtcctgca gaaaacagtc aacgacggga ttcaaggcgg
    15001 cctgcaagcc gacacgatcg agctgctcgc ggctctcgtc gtggggacca ccgtcattgg
    15061 tgccgtgcag gcctatctga cgggtcgggg cgccgaagcc gtcgcccatc gcctgcgcac
    15121 ccgtctgggt cgtcgctatg tcagcatgac gatcagcgag ctcgatgcgg ccaacaccgc
    15181 cgacctgctc tcacgcgcca acgcggacag caccatggtg aagcagttcc tgtctgccgg
    15241 gatcctgccg gttgccggtt ctgttctcat gctcgccgga acaacggtct tcatgatcat
    15301 gtccgacccg atactgttcg cggtgacagc agcggccttc gtcctcggcc tgtccttggt
    15361 gatcgcagtc accaaccggg cgaacagcat gtccgccgaa gtgcaggagg ctctgggaga
    15421 tttctccgtg agcaccgagc gcatgctctc agcgctgcgc accatcaagg cgacgaatgc
    15481 tgaaccgctg gagctggatc atctacgcct cagctcccac aatctttacc gcaagggtct
    15541 gaggatcacc gtcctgtccg cgtgcgtcca gcctgctctc aatgtctgca tccaaggctc
    15601 gatcgccgca gtgatcgtgg tcggcaccgc acggctggcc tcgggtgcga caacattggg
    15661 aaccctgctc gcctacatca cctacatgtt catgatgatc gcaccgatca gcagcctcgg
    15721 ccaggcattc acccagatgc agatcggcct gggcgccctc aagcgctgct atgaggttga
    15781 tttctttgaa tcagaggatg acgtgcgcgc cgaccatcag actgccatcg gcaccgcatc
    15841 gggagacgaa ctgctgcgct tcgacagcgt ctccttctca tacgagccgg gaactccagt
    15901 gctcactgat gtcaacttcg tcctgcgccg tggagaaaca gtcaccatcg tcggtcgatc
    15961 cggttcaggc aagtccacgc tcctggaact catcgaacga ttctaccacc ccgacgccgg
    16021 gcacatctca ctcggcggtg tcccgatcga ccagctcgac ctgaactcct accgcagacg
    16081 cctcgccctc gtcggtcagg actcgatcgt gctcaccggc acgctgagag agaatctgga
    16141 actcggctgc caccgccacc cggactccac cctgtacgag gcccttgagc acgtcggtct
    16201 caccgatctg ctggggaaga aggatttcgg tcttgacacg gacgtgggcc aagccggaat
    16261 cactctctcc ggcggccagc gacagcgaat cgcctgggcc cgagtgctgc tcagcgacgc
    16321 cgacatcatc ctcatggacg agccggactc caatcttgat cccgtgacca ggtcctcctt
    16381 gacccatctg ctcgagagct tcgccgcaac gcgcacggtg ctcatcgtct cgcacaacct
    16441 cgagcacctc aactcgagcg accgcgtcct ggtcatggat catggcagca tactggccga
    16501 cggctgccgc caggagcttc ttgcaacaac gtccgagtac caggatctgc tggcccccac
    16561 gcaagcagca gcatgagaga agaactgcca tgacaacagg gacttccacc atccccagca
    16621 cgaggccctc cgacccggca cccatctcct tcgaacacgt gacgaagagc tatgaaagtc
    16681 gcctcatcct cgacgacgtc agcttcagca tcgagtccgg agcagtcacc gggctgctcg
    16741 gcccgaatgg ttcgggcaag acgacgatgc tgcgctgtct tctcggactc gccagccctg
    16801 actccggcat ctgcctggtg gaggggaatc ggtatgatgc catccccgta ccgtctcgtc
    16861 tggtcggcgc tctgtgcgaa aacgctgggc tgcatccgaa ccgcagggca gccgaatgcg
    16921 tcgccctggc cagggccgcc gccgggctga ccgatcctca cgccgtcgac gcgcacttgg
    16981 agcaggtcgg gctggcggat gcaggcccca tgagggtccg tgagatgagc ctgggcatgc
    17041 gtcaacgcct cagcctggcc ctcgcgctgg tgggcgatcc acatgttctc gtcctcgatg
    17101 aaccatccaa cggtctcgat cccgagggca tggaatggtt ccgcaccctc ctccggcgct
    17161 tcgcggccag tggcgggtcg gtgctgatca ccagtcacat cctggccgag ctgcaacgca
    17221 cgatagacgc cgtcgtcata gttcgaggag gccgcgtcgt ggcacagtcg gacaccttgc
    17281 ccgacgatct tgattctttc tatctcgcca cttcaggaaa tcgaggatga gtaccatgaa
    17341 cgttgagatc atgcgactgc gccaaggccg aatcgcctcc accatgacga tcatcctgat
    17401 catcgcgact ttcttggtcg ccacactcga agccttcgcg agggatacga tcaacgccct
    17461 catttctctc aacagagtca tccccaatgc gacgcaggct caatccatgt cccccgagga
    17521 tctggcgaaa ctgtcattgg accagcccgg cttgcagctc acagccgccg ccaatgccgg
    17581 cggcgtcggc ggagtgagcc cggcggctct cgcaatgatg atcatggggg gcctgttcat
    17641 cacccgcgag taccacttcg cctccatgac aagcgcggcc gtggcgttgc cccgccgcgg
    17701 gcagctctac cggaacaagt gcgcggccgc tgcactcgcc tcattcgtcg ccgcgttcgg
    17761 tctcaccgcg gtcagactgc tcgtcctgtt caccgctctc gccgtgcagc gcatcaacct
    17821 ggcactggat ccgttcgccc tggtcatgtc ggagttgcgc ggactcgtca cactcgtgct
    17881 gtgcggtgtc ctcggcgccg gcctcggctt cctgctgcgt cggcaaaccg ttctgctcct
    17941 cctgctgggc ggtctgttcg tcgtcgagtc gaccttccgc tcactcgcca cgctcaccgg
    18001 cgccgacatc ctccacggct gtctcccgct gagcgccacg gggctttcga cgcagccggg
    18061 cgcccagggc tggctcgcag cgggtatcgt cgtggcatgg tctgccatcg tggtgacatg
    18121 gggtgcattc tgcttcaacc gcagggagct gaccttctcg gcgttgtagc gctgctggcc
    18181 ggcatcggac ggagacatgc acatgagcag aggtgcggct gagcgcgtca accagcagct
    18241 gcggcagacc gtactggcat cgttcctggt gagtctcttg aacgtgctgc tggtggcgaa
    18301 ctcagaaaac tcgctcgccc agattctgtg gcagatcggc ctgaccgttc tcggggtcgt
    18361 ctgcaccatc attctcatca accgaccggt cgtggcgttc gcgatcgtcc acactgctgt
    18421 tctcgttgca gcactgacgc agcagaatcc attcgtcacg cagttcctgc tctatctgcc
    18481 gctgtgcttc tggctgggac ggcgtacccg gtcacggacc agctccgtca ccgcgatgat
    18541 cggcctcacg acgacgatcg gggccttcgt gctcgccccc gtgcgcaccg gctccgacgg
    18601 catcgctctc ctcgcaccag tcggtttcgt ctcgggctcg ctcttcatcg gggcccccac
    18661 cctggtcggg gcctggatgc ggatcgcgaa cgaacgagcg gttggagtgg agaccctcct
    18721 gaaagcagaa cgggccgaga gcgaagcgag gatcgccaag gcactcgagg acgaacgcgg
    18781 gctcatggcc cgggaactgc acgacatcgc ctcccatcac atgactgccg tcctgctcga
    18841 cgccaggctc gcccgacgca tgctccccgg aaacccgcaa cgcgcagcag agctgctcga
    18901 agaactgacc cgcgaggccg gcagcgccag cgagagcctg cacgaggtgg tcggcatcct
    18961 cgcggcgggt tcccaggccc ccaccgcccc ccagccgacc ctcgcggaca ttcccgagct
    19021 gttgcgtcgg gccagggcga tcaaccccga catcggtgtc gcgatgcctc aggacccgaa
    19081 ggtctcacca gctgtcgggc tcgccctgta ccggatcgtc caggagtcgt tgacgaacgc
    19141 ccaccgctat gccccaggag cccccatcat ggtggacctg accatcaaga acggttggat
    19201 gagcctgtcc gtgaccaatg ggctggcgac ccaaccgacc tccggcatca gcgggtcggg
    19261 gctgggcatc cagggcatgc gcatgcgctg cgagctgctc ggcggcactt tgacagcagg
    19321 cccgcacgag ggcggctggg ccgtccgggc ccggctgccg caacgtgccg gggaggatgg
    19381 ccccaccgcc ctcgcgggga cttaagaagg agacacgagt gtccagaagt gcgatgaccg
    19441 gtgaacgctc cagcgggcat cgttgtcact gtccacgaag gagacgggca tgaacatccg
    19501 atcgcacagc tctcagccgg tcatcggcta catcatcgtc gtcatcgcct tggcgggcat
    19561 gatctgctac agcctgctgt tctgggacga catgcctgcg caggtcatca cccgtcaggc
    19621 cgccggccgc cacggcgcgt cggccgttcc ccgcggcgtc tcggcggccg ccatgcccgc
    19681 cacgctgctg gtctgcacgc tgctgctgat gctcatgccg ctctggaacc gcctggtcgg
    19741 atccacgccc ctgcgccccg gccctgacca gcgccagcag acgaggatct ggaccgcgat
    19801 cctggccatg ctgtcagcgc tcctgctcac cctgcacata ggcatcaccg acatgtgcac
    19861 gggcaggggt cctcagttcc cgcagctggc cgcctacggg atggccgtca ccctcatcgg
    19921 cctggccgcg atcaccgcga tcctgcgcgt acgggcccac cgggccatcg tcatgggtct
    19981 cgccctcggc ggcgcgctcg tcgcagcact ggcgcacggc ctgccccgtg cggccatgac
    20041 cgtcgggacg gtgatcatgc tcggcggcat cgcggccgcc accctgctgc cgcagctcag
    20101 gaacgacggc ggacgccgct gaccccggac gacatccgcg ggctgctggc ctggggcccg
    20161 cacacccgtc cggccccgtc ccgaccccgg cttcgctgcc gcccctccgc tcccacctca
    20221 ctttccggtt agcacccggg acatgtccga ggtgcgagcg caaaagcgag gtgggaacgg
    20281 gagaagaggc gggagaagca ggcagcgccg gaccggggaa cgggacgagg tgggaacggg
    20341 acggggtggg gcgcaccgga tcgggggccg cggtgggagc acgccccatg ttccgttctc
    20401 cggttcggcg cgacgggccc cggtggcgta gctttgttcc cgtgagcaca cgtgtatatg
    20461 tcgcgtcccc cgatgcccgg gccgatctga gcgccgccgc tcaggccatc gccgaggccg
    20521 ccggacgcca gtccagtccc gccgtcctct tccacccgct ggccgcgcag gcctcctcgg
    20581 cccgcctcgt cggcgcctcc ttcgacgaat tcgccaggag caccgacgag gccgagacgg
    20641 gcatcatcga gcgcttcgag gcgctcgccg ccgccgggcc cgtcgtcgcc gtgggcaccg
    20701 actactccgg cgtcaccgcc cccaccgagc tggccctcaa cggccgcctc gccgccgacc
    20761 tggccgcccc ggtcgtcctg gtcgtcgacg cctcccaggg ccccgaccac gccctcggcc
    20821 tggcccgcgt cgccctggac ggcctggccg cccagcacgc caccgtcgtg gcgatcatcg
    20881 ccaccggccc gacccacacc gacgccaccc gcacccttct cgcctcgctc ggcgtgcccg
    20941 ccgccgtcct cggcgacgac ctgtctgccg tgctggccgc gaccgatgtg acgatcacca
    21001 cccgtacccc ggcccgcttc agccacgagc tcatggccac ggccagggcc gacgtgcgga
    21061 cgatcgtgct gcccgagagc gaggaccccc gcatcctcga ggccgcctcg gtcgtcgccg
    21121 cccgcggcgt cgccaggatc gtcctgctcg gcgaggagga gcaggtgcgc gccgacgcga
    21181 agaggcaggg cctcgacctg accggcgtcg agatcgtctc gatgaacaac ccggggctcg
    21241 tcgagtccta cgccgccaag ttcgccgagc tgcgcgccaa gaagggcgtc accctcgagc
    21301 aggcccgcga ggccatggcc gacggcgcct gcttcggcac gatgatggtg tacatgggcg
    21361 gcgccgacgg cctcgtctcg ggcgccaacc acacgacggc caacaccatc cgcccggccc
    21421 tccaggtcat caagacgaac ccgggcatga agaccgtctc gggcgccttc ctcatgagcc
    21481 tcgccgaccg cgtgctgctg ttcgccgact gcgccgtcac cccgaacccg gagccggccc
    21541 agctcgccga catcgccctc gcgagcgccc agaccgcccg catgttcggc atcgacccca
    21601 aggtcgccat gctgacctac tcgacgggca cctccggcag cggtccggac gtcgaccggg
    21661 tccgcgccgg ctacgaggag gccgtccagc gcgcccccga ggagcggatc gccggcccga
    21721 tccagttcga cgccgccatc gatcccgtcg tcggggccaa gaagatgccc gactccgagg
    21781 tcgccggccg cgcgaccgtg ttcgtcttcc ccgatctgga ggccggcaac atcggctaca
    21841 agatctgcca gcgcaccgcc ggcgccgtgg cggtcggccc gctgctgcag ggcctgcgcc
    21901 gccccgtcaa cgacctgtcg cgcggcgccc tcgtcgacga catcgtcaac accatcatca
    21961 tgaccgccat ccaggcccag ggcacgaacg gcccgctcgc ctgagagtcc tggcctgaca
    22021 aggagagaca tgaccgaacc aatcctggtg ctgaactgcg gctccagctc cctcaagtac
    22081 cagctcatcg accccgactc cgaggccgtg ctggccaagg gcctggtgga gcgcatcggc
    22141 gacgcgagcg acggcatcgt cacccacgag gtcggcgacg acgagttcac ggtcaccccg
    22201 cggctgcccg accacacggt ggccctcaag gcggtcttca cgatgttcgc cgatcacggc
    22261 ccctcgctcg acgacgtcgc ggcggtcgcc caccgcacgg tgcacggcgg cgatcgcttc
    22321 gccgccccga ccgtcatcga cgacgaggtg ctggacaccc tcgaggagct cgtcccgctg
    22381 gcgccgctgc acaacccggc cgggatcaag ggcatccgcg ccgcccgcac actgctcccg
    22441 gacgtgccgc acgtcggcat cttcgacacc gcgttcttcg tcaacctgcc ggccgaggcc
    22501 cacacctacg ccatcgaccg cgggctggcc gccaggcacg cgatccgcaa gtacggcttc
    22561 cacggcacga gtcaccagta cgtcgccggc ctggtgcccg gcgtgctggg cgccgacccg
    22621 gcggagctgc gccagatcgt ctgccacctc ggcaacggcg cctcgatctc ggccgtcaag
    22681 ggcggccgtg ccgtcgagac ctcgatgggc ctgaccccgc tggccggcct cgt
//
