LOCUS       NZ_CP031479.1          10864 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP031479.1 Vibrio anguillarum strain PF4-E1-1 chromosome 1.
ACCESSION   NZ_CP031479
VERSION     NZ_CP031479.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:58:11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1459202
            Orig. end    :: 1470066
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10864
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1464202:1465066](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5864)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10864
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10864
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="3"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             229..591
                     /locus_tag="ctg1_1273"
                     /transl_table=11
                     /translation="MTIHRINPSKRWSDITVFNGIAHFVEVADSDTKADMKGQVEQILA
                     QAEQQLTAIDSDRRRVLSVTIYVTDFAHFAALNEVWDSWFPEGCAPSRACVQAQLASPD
                     YLVEMAFVAAAGPKFQ"
     PFAM_domain     325..570
                     /aSDomain="Ribonuc_L-PSP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01042.23"
                     /description="Endoribonuclease L-PSP"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1273_0081"
                     /evalue="2.10E-19"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="114"
                     /protein_start="32"
                     /score="69.8"
                     /tool="antismash"
                     /translation="KADMKGQVEQILAQAEQQLTAIDSDRRRVLSVTIYVTDFAHFAAL
                     NEVWDSWFPEGCAPSRACVQAQLASPDYLVEMAFVAA"
     CDS             complement(703..804)
                     /locus_tag="ctg1_1274"
                     /transl_table=11
                     /translation="MWYFCWVLGVLLACAFGIINGLWLEQAEHFDES"
     aSDomain        complement(721..804)
                     /aSDomain="TIGR02106"
                     /aSTool="tigrfam"
                     /description="cyd_oper_ybgT: cyd operon protein YbgT"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1274_0021"
                     /evalue="3.50E-18"
                     /identifier="TIGR02106"
                     /label="ctg1_1274"
                     /locus_tag="ctg1_1274"
                     /protein_end="28"
                     /protein_start="0"
                     /score="63.6"
                     /tool="antismash"
                     /translation="MWYFCWVLGVLLACAFGIINGLWLEQAE"
     PFAM_domain     complement(727..804)
                     /aSDomain="YbgT_YccB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08173.13"
                     /description="Membrane bound YbgT-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1274_0082"
                     /evalue="5.80E-16"
                     /label="ctg1_1274"
                     /locus_tag="ctg1_1274"
                     /protein_end="26"
                     /protein_start="0"
                     /score="58.3"
                     /tool="antismash"
                     /translation="MWYFCWVLGVLLACAFGIINGLWLEQ"
     CDS             complement(817..1953)
                     /locus_tag="ctg1_1275"
                     /transl_table=11
                     /translation="MFDYETLRLLTWAIVGMLLIGFIITDGFDMGVAALLPILGRSDVE
                     RRVMINSIAPHWDGNQVWLITAGGAIFAIWPLVYATAFSSFYLAMMLLLAALWLRPIGM
                     DYRSKIDNPSWRKACDNALFISGVVPPLIFGIGFGNLLVGVPFQLNNLLMLDYQGHFWD
                     LFTPFPLLCGLLSLAIVVTQGATFLQLKTCDVLCERTHSASVVSASIAVALFLIGGFFA
                     ANMAGYIIVSPIVTDAASNPLHKEVVSIARHLLHNYQAHAMLWLIPCVGIASLLACIWA
                     SLKRASGGAFLFSSLAIACIIFTAGVALFPMIMPSSLMPSHSLTIWDATSSQKTLNIIT
                     IVAILVVPVILSYTTWGYYKMFGRLSDDYIRNHSTSLY"
     aSDomain        complement(820..1953)
                     /aSDomain="TIGR00203"
                     /aSTool="tigrfam"
                     /description="cydB: cytochrome d ubiquinol oxidase, subunit
                     II"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1275_0022"
                     /evalue="1.70E-139"
                     /identifier="TIGR00203"
                     /label="ctg1_1275"
                     /locus_tag="ctg1_1275"
                     /protein_end="378"
                     /protein_start="0"
                     /score="463.2"
                     /tool="antismash"
                     /translation="MFDYETLRLLTWAIVGMLLIGFIITDGFDMGVAALLPILGRSDVE
                     RRVMINSIAPHWDGNQVWLITAGGAIFAIWPLVYATAFSSFYLAMMLLLAALWLRPIGM
                     DYRSKIDNPSWRKACDNALFISGVVPPLIFGIGFGNLLVGVPFQLNNLLMLDYQGHFWD
                     LFTPFPLLCGLLSLAIVVTQGATFLQLKTCDVLCERTHSASVVSASIAVALFLIGGFFA
                     ANMAGYIIVSPIVTDAASNPLHKEVVSIARHLLHNYQAHAMLWLIPCVGIASLLACIWA
                     SLKRASGGAFLFSSLAIACIIFTAGVALFPMIMPSSLMPSHSLTIWDATSSQKTLNIIT
                     IVAILVVPVILSYTTWGYYKMFGRLSDDYIRNHSTSLY"
     PFAM_domain     complement(871..1935)
                     /aSDomain="Cyt_bd_oxida_II"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02322.17"
                     /description="Cytochrome bd terminal oxidase subunit II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1275_0083"
                     /evalue="1.10E-92"
                     /label="ctg1_1275"
                     /locus_tag="ctg1_1275"
                     /protein_end="361"
                     /protein_start="6"
                     /score="310.8"
                     /tool="antismash"
                     /translation="LRLLTWAIVGMLLIGFIITDGFDMGVAALLPILGRSDVERRVMIN
                     SIAPHWDGNQVWLITAGGAIFAIWPLVYATAFSSFYLAMMLLLAALWLRPIGMDYRSKI
                     DNPSWRKACDNALFISGVVPPLIFGIGFGNLLVGVPFQLNNLLMLDYQGHFWDLFTPFP
                     LLCGLLSLAIVVTQGATFLQLKTCDVLCERTHSASVVSASIAVALFLIGGFFAANMAGY
                     IIVSPIVTDAASNPLHKEVVSIARHLLHNYQAHAMLWLIPCVGIASLLACIWASLKRAS
                     GGAFLFSSLAIACIIFTAGVALFPMIMPSSLMPSHSLTIWDATSSQKTLNIITIVAILV
                     VPVILSYTTWGYYKM"
     CDS             complement(1965..3545)
                     /locus_tag="ctg1_1276"
                     /transl_table=11
                     /translation="MLTDVVELSRFQFASTALYHFIFVPLTIGLSFLLAIMESLYVMTG
                     KTVYKDMTRFWGKLFGINFAVGVATGLTMEFQFGTNWAYYSHYVGDIFGAPLAIEALIA
                     FFLESTLVGLFFFGWDRLSKRQHLSVTWLTALGSNFSGLWILMANGWMQNPVGAEFNYQ
                     TMRMEMINFAEVIFNPVTQVKFVHTVAAGYTTGALFIMGISAYYLLKKRDLPFARRSFA
                     VACAFGMASITATLLLGDESGYTLGEVQQVKLAAIEAEWDTEQAPASFTLFGLPNQETM
                     HTDAAIKVPYLMGIIATRSLDEPVIGLKDLMARSEERIRNGMLAYGLLEALRNGDDSLQ
                     NIAQFETLKEDLGYGLLLKKYTDKVTDATESQIKQAAQDTIPQVAPLFWSFRIMVACGM
                     AMFAVIGLCFIQICRRKIGTQPWLLKAALFAIPLPWIASEAGWFVAEFGRQPWAIGEVL
                     PVNMAVSNLSPSDLWISLGLVYLLYSAFLVVEMYLMVKFARRGPSALHTGRYHFETQDG
                     HGSLSHVHH"
     PFAM_domain     complement(2040..3524)
                     /aSDomain="Cyt_bd_oxida_I"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01654.19"
                     /description="Cytochrome bd terminal oxidase subunit I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1276_0084"
                     /evalue="7.50E-174"
                     /label="ctg1_1276"
                     /locus_tag="ctg1_1276"
                     /protein_end="502"
                     /protein_start="7"
                     /score="578.3"
                     /tool="antismash"
                     /translation="LSRFQFASTALYHFIFVPLTIGLSFLLAIMESLYVMTGKTVYKDM
                     TRFWGKLFGINFAVGVATGLTMEFQFGTNWAYYSHYVGDIFGAPLAIEALIAFFLESTL
                     VGLFFFGWDRLSKRQHLSVTWLTALGSNFSGLWILMANGWMQNPVGAEFNYQTMRMEMI
                     NFAEVIFNPVTQVKFVHTVAAGYTTGALFIMGISAYYLLKKRDLPFARRSFAVACAFGM
                     ASITATLLLGDESGYTLGEVQQVKLAAIEAEWDTEQAPASFTLFGLPNQETMHTDAAIK
                     VPYLMGIIATRSLDEPVIGLKDLMARSEERIRNGMLAYGLLEALRNGDDSLQNIAQFET
                     LKEDLGYGLLLKKYTDKVTDATESQIKQAAQDTIPQVAPLFWSFRIMVACGMAMFAVIG
                     LCFIQICRRKIGTQPWLLKAALFAIPLPWIASEAGWFVAEFGRQPWAIGEVLPVNMAVS
                     NLSPSDLWISLGLVYLLYSAFLVVEMYLMVKFARRGP"
     CDS             complement(3666..4265)
                     /locus_tag="ctg1_1277"
                     /transl_table=11
                     /translation="MIHSALNWYDGVIEKFKKFDFIVLLAIRLFLVPVIFVGAHSKVVG
                     FAGTVAWFGASTADGGLNLPFPELLAFLAAATEVLGCICIALGLFTRIMAIPMILMMSV
                     ASAMVHWKHGWDAIATSSMEATVRLNGFIEWLAVNFPGRYNYITELGDPVMLNNGMEFA
                     ATYFVMLMVLFIYGGGRYVSLDYWLKKPFTRTPQTA"
     PFAM_domain     complement(3933..4196)
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1277_0085"
                     /evalue="2.40E-15"
                     /label="ctg1_1277"
                     /locus_tag="ctg1_1277"
                     /protein_end="111"
                     /protein_start="23"
                     /score="57.0"
                     /tool="antismash"
                     /translation="LLAIRLFLVPVIFVGAHSKVVGFAGTVAWFGASTADGGLNLPFPE
                     LLAFLAAATEVLGCICIALGLFTRIMAIPMILMMSVASAMVHW"
     CDS             complement(4262..5008)
                     /locus_tag="ctg1_1278"
                     /transl_table=11
                     /translation="MLKPPMNMSMSMHALTCVIRSPVAQGEPPCRYREFIRANIYSVIK
                     HTFPLFYAQLNEETLYILTDEWLVIHGAMEPEFHQIATEFVQFIQQQNNHNASVNLSAE
                     QIALLEYEWIVFNAEMDSAHVPNLKVWWDDVEAQPEAFCIQLNPTLKLVEVPFLVHPES
                     VTFLIQEQKTVCYGVFRHASHQVVSQKLREVDIALIQMIQNAPAQSLTQLEQQIAQHLS
                     NFHFLAWVQTFQQQGLISLYLLGETL"
     CDS             complement(5001..5864)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1279"
                     /sec_met_domain="DUF692 (E-value: 8.9e-89, bitscore: 294.5,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAIDRTSKGIGLRSEHIDLLCQLPDHPDIDFLELAPENWMNMGG
                     LKREQLQQIAKHYPLVAHGLSLSIGDCQPLNKAFVKKVAAFLDEFNIDIYSEHLSFSRD
                     AQGYLYELLPIPRYKESIAYLVDRIHCVQDIVQRPLVLENISYYHSYGKEIPEGEFITE
                     IVERSGCQLLIDINNVYVNSRNHNYCPFDMLATLPSEAICYYHIAGHLKEREDFLLDTH
                     GKPVQQEVIDLARYAYAQQGSRPLLLERDHHVPPLVVLTEELRTIHHDIMQPAPSLVID
                     VERSHA"
     PFAM_domain     complement(5061..5837)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1279_0086"
                     /evalue="3.10E-92"
                     /label="ctg1_1279"
                     /locus_tag="ctg1_1279"
                     /protein_end="268"
                     /protein_start="9"
                     /score="308.6"
                     /tool="antismash"
                     /translation="GIGLRSEHIDLLCQLPDHPDIDFLELAPENWMNMGGLKREQLQQI
                     AKHYPLVAHGLSLSIGDCQPLNKAFVKKVAAFLDEFNIDIYSEHLSFSRDAQGYLYELL
                     PIPRYKESIAYLVDRIHCVQDIVQRPLVLENISYYHSYGKEIPEGEFITEIVERSGCQL
                     LIDINNVYVNSRNHNYCPFDMLATLPSEAICYYHIAGHLKEREDFLLDTHGKPVQQEVI
                     DLARYAYAQQGSRPLLLERDHHVPPLVVLTEELRTIH"
     CDS             complement(5852..6166)
                     /locus_tag="ctg1_1280"
                     /transl_table=11
                     /translation="MNCKIVLSIAMTSAIALHPAMSVAETSTEAPVSAQPTSQNGGKCA
                     AGKCGTEKRFEKQDLKSDPQGRLVRARDGKCGLTAEGIAPSAETITLTNSKITGGVCGQ
                     "
     CDS             complement(6156..7112)
                     /locus_tag="ctg1_1281"
                     /transl_table=11
                     /translation="MKQPLKALVLAISLSCGAIGAYANSLEPLDKEFTLQVLGSGGPIS
                     DDLRSSSAEVIWWKGKSKIMIDAGGGAYLRFGQSGSKLEDLDFLGITHFHTDHVADLPA
                     LLKGGYFFKREDPLDIAGPQAGSAFPSLSGYMDALFNSKDGAYAYLNGLYDGSDGLFPV
                     TITDVSYKTTTPTKVYQQDGLTIYALGIPHGDVPCLAYRIESDQGVIVISADQNGSNPA
                     FLDFAQGADILVMPMAVHESADEVSAFMHAKPSVIGEIAAKINPKLLVLNHWMGVGLKH
                     KSESTKIIKQFYHGEVIAARDLSSYPMSSVKEITHEL"
     PFAM_domain     complement(6291..6923)
                     /aSDomain="Lactamase_B_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12706.9"
                     /description="Beta-lactamase superfamily domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1281_0087"
                     /evalue="3.10E-12"
                     /label="ctg1_1281"
                     /locus_tag="ctg1_1281"
                     /protein_end="274"
                     /protein_start="63"
                     /score="46.5"
                     /tool="antismash"
                     /translation="IMIDAGGGAYLRFGQSGSKLEDLDFLGITHFHTDHVADLPALLKG
                     GYFFKREDPLDIAGPQAGSAFPSLSGYMDALFNSKDGAYAYLNGLYDGSDGLFPVTITD
                     VSYKTTTPTKVYQQDGLTIYALGIPHGDVPCLAYRIESDQGVIVISADQNGSNPAFLDF
                     AQGADILVMPMAVHESADEVSAFMHAKPSVIGEIAAKINPKLLVLNHW"
     CDS             7497..7928
                     /locus_tag="ctg1_1282"
                     /transl_table=11
                     /translation="MMSVMFMMKMKPSYYVIPMLIAFNVHAADSQCDVISSQLHDVSNG
                     SEAVEHSGGYSVRDNPPIRCAEVVFKTKQSYDKVVAWMNDDFTAIYVDGSEATSNMVRF
                     REDDVKAGYVKMKVNQPITAYVCFGQSSVPISQIECDIK"
ORIGIN
        1 attgccgcat ttgacgtcgg tggccaattc ccgcgtgact tcactttgtc tgcggatgga
       61 gattggttgt tggttgctag ccaacattca cacacaatcg ccagttatcg ccgagatgaa
      121 accacaggca ggttggttgc cagcggcttt agctgcaaag tcggcgcgcc agtctgtgtg
      181 atcgaacagc actgttgcga gttatcttta ccataaagag agaaattaat gactattcat
      241 cgtattaatc caagtaaacg ttggtctgac attaccgtat tcaacggcat tgcccacttt
      301 gtggaagtgg ctgatagcga tacaaaagcc gatatgaaag ggcaggttga gcagatctta
      361 gcccaagctg agcagcagtt gacggcgatc gacagcgaca gacgtcgcgt gttatcggtg
      421 acgatttatg tcacggattt tgctcatttc gccgctttga atgaagtgtg ggatagctgg
      481 tttccagaag gatgcgcacc aagccgagcc tgcgttcaag cgcaattggc aagccctgac
      541 tatctggttg aaatggcttt tgttgccgcg gctggcccaa aatttcagta aatacgtttg
      601 acgatgtgaa aaaaatgacg ctaaaaatag cgccattttt ttatctcaaa gcccgatgtt
      661 cttaaacttt attaaccggt tatctgcttg catatgagtg agttacgatt catcgaaatg
      721 ctcagcttgc tcaagccaca atccattgat tataccaaat gcgcaggcga gtaatacgcc
      781 aagaacccaa cagaaatacc acatcagtta tctcctttag tacagcgatg tgctgtggtt
      841 gcgaatgtaa tcatcactca atcgaccgaa cattttgtag taaccccaag tcgtgtaact
      901 gaggatgact ggcaccacta agatggcgac aatcgtgatg atattgagtg ttttctggct
      961 ggatgtggca tcccaaatcg tcaaactgtg tgatggcatt aagcttgatg gcatgatcat
     1021 cggaaatagc gccacgcctg ccgtaaaaat aatgcatgca atagcaaggc tagagaataa
     1081 gaatgccccg ccagatgctc gtttcaggct tgcccatatg cacgccaata agctcgcgat
     1141 gcccacgcaa gggatcaacc acagcatggc gtgtgcttga tagttatgca gtaaatgacg
     1201 agcgatgcta accacctctt tatgcaaggg gtttgaagcg gcatccgtga caattgggct
     1261 cacgataata taacccgcca tgttggctgc aaagaatccg ccgatgagaa ataaagccac
     1321 cgcaatgctg gcactgacga ccgacgcgct atgggttcgc tcgcataaca catcacaagt
     1381 tttgagctgt aaaaacgttg cgccttgagt gacgacgatg gcaaggctga gcaggccaca
     1441 cagtagtgga aatggtgtga atagatccca aaaatggcct tggtaatcga gcatcaataa
     1501 gttattgagc tgaaaaggga ctcctaccaa taaattacca aaaccaatgc caaagatgag
     1561 gggcggcaca acgccactga tgaacagtgc gttatcgcac gccttgcgcc atgaggggtt
     1621 atcgattttt gagcgataat ccataccaat tgggcgcagc cataacgcag caagtagcaa
     1681 catcatcgct aaatagaaac tagaaaatgc ggtggcgtaa accagtggcc agatagcgaa
     1741 aatcgcaccg ccagcagtaa tcaaccacac ttggttgcca tcccaatgag gcgcgatact
     1801 gttgatcatc actcttcgtt caacatcact gcgtcccaaa atgggcagta gcgctgcaac
     1861 gcccatatca aagccatcgg tgatgataaa accaatcaat agcataccga caatcgccca
     1921 agtcagcaga cgtaaggttt cgtaatcaaa cattgtgttc tcccttaatg gtgtacgtga
     1981 gatagagatc cgtgcccatc ttgcgtttca aaatggtaac gtccggtatg tagggcactt
     2041 gggccgcgcc gagcaaactt caccatcagg tacatttcca ccaccaaaaa tgcgctatag
     2101 agtaagtaaa ctaggcccag tgaaatccat aaatcgctgg gtgataggtt agatacagcc
     2161 atattaaccg gaagtacttc accgatagcc caaggttggc ggccaaactc agcgacaaac
     2221 caacccgctt cgctggcaat ccagggaagt ggaatagcga ataatgccgc cttaagtaac
     2281 caaggctgag tgccgatttt tcgccgacaa atttggatga aacagagccc aatcacagcg
     2341 aacatcgcca taccgcaggc caccatgatg cggaagctcc aaaacagagg tgcaacttgc
     2401 ggaatggtat cttgcgcggc ttgtttgatt tggctttcag tcgcatcagt tactttgtcg
     2461 gtgtattttt tgagtaataa accgtacccc aaatcctctt ttagcgtttc aaattgagcg
     2521 atgttttgca gtgaatcgtc accattgcgt aaggcttcta atagcccgta agcgagcatg
     2581 ccattgcgaa tgcgctcttc actgcgcgcc atcaaatctt ttaagccgat gacgggctca
     2641 tccaatgaac gcgtggcgat aatacccatc aaataaggga ctttaatcgc cgcgtctgtg
     2701 tgcatggttt cttggttagg cagcccaaac agagtaaaag aggccggggc ttgttcggta
     2761 tcccactcgg cttcaatggc ggccagtttc acctgttgca cttcacctaa ggtgtaacct
     2821 gactcatcac ctagcaataa agtggcggta atggatgcca tgccaaaagc gcaagccaca
     2881 gcaaatgagc gacgcgcaaa gggaaggtcg cgctttttta ataggtagta agcgctgata
     2941 cccatgataa acagtgcgcc tgtggtgtaa cccgccgcaa cggtatgcac aaacttcact
     3001 tgggttactg ggttaaaaat gacctcagca aagttgatca tttccatacg catggtttga
     3061 tagttaaact ccgcaccgac ggggttttgc atccagccgt tggccatcaa aatccacaat
     3121 ccagaaaagt tagagcctaa agcggttaac caagtcacgc ttaaatgctg acgcttagaa
     3181 aggcgatccc agccgaagaa aaatagccca actaaggtag attcaaggaa aaaggcaatc
     3241 aaagcttcaa tcgccagtgg ggcaccaaaa atgtcaccca cataatgaga gtagtacgcc
     3301 cagttggtgc caaattgaaa ctccatagtg aggccggtgg caacgccaac ggcgaagttg
     3361 atgccaaaca gcttgcccca aaagcgagtc atgtctttgt agacggtttt tccggtcatc
     3421 acatacagcg attccatgat cgccagtaaa aacgataagc caatggtcag cggaacaaaa
     3481 ataaaatggt aaagcgccgt actggcgaac tggaaccgtg acagttccac cacatctgta
     3541 agcataaagt ctccctcccg ccagcaaaat ggcaggtaag atagtcagag atgaatgtgt
     3601 gattgataac gcctgccact tgaagctgcg ggcggcaact tcaagttagt aggcatcatt
     3661 aggtgttaag cagtttgagg cgtgcgagtg aatggttttt ttagccagta gtcgaggctg
     3721 acgtagcggc caccaccata aatgaaaaga accatcagca tcacaaagta agtagccgca
     3781 aattccatcc cgttattgag catcacaggg tcgccaagtt ctgtgatgta gttgtagcgg
     3841 cccggaaaat tgaccgccaa ccattcaata aaaccgttta agcgcaccgt cgcttccata
     3901 ctgctggtgg caatcgcgtc ccagccatgt ttccagtgca ccattgcgct cgccacactc
     3961 atcatgagaa tcatagggat agccataatg cgagtaaaaa gaccaagtgc gatgcatata
     4021 cagccgagaa cttctgtcgc ggcagctaaa aatgccagca gttctggaaa aggtagattt
     4081 aaaccaccat cggcggttga ggcgccaaac caagcaacgg ttccagcgaa accaaccact
     4141 ttggaatgag caccgacaaa aatcaccggc acgagaaaaa gtcgaatcgc aagtagtact
     4201 ataaaatcga attttttaaa tttttcgatc acgccatcgt accaattgag ggctgagtga
     4261 atcatagagt ttctcctaat aaatacaggc tgatgagtcc ttgttgctga aacgtttgaa
     4321 cccacgccaa aaaatggaag ttggataggt gttgagctat ctgttgttct agttgcgtta
     4381 gtgactgcgc tggggcgttt tgaatcatct gaattagggc gatatccact tctctgagtt
     4441 tttgtgatac cacctgatgc gatgcatgac gaaatacccc ataacagacc gttttctgtt
     4501 cttgaatcaa aaaagtgacc gattctggat ggacaagaaa aggcacttcg accagtttta
     4561 acgttgggtt aagctgtatg cagaacgcct ccggttgagc ttcaacatca tcccaccata
     4621 ctttgagatt cggcacatga gcgctatcca tttcagcgtt gaaaacgatc cattcatatt
     4681 caagcagtgc gatttgctca gcactgaggt taacactggc gttatggtta ttttgctgtt
     4741 ggataaactg aacaaattca gtcgcaatct gatggaactc aggctccata gcgccatgta
     4801 ttaccagcca ttcgtccgtc aaaatgtaga gtgtttcctc gttaagttga gcgtaaaaca
     4861 gaggaaaagt gtgcttaatg acagagtaga tattcgctcg aatgaactct cgataacggc
     4921 agggcggttc gccttgcgcg acaggagagc ggatcacaca ggtcagtgcg tgcattgaca
     4981 tactcatgtt cattggtggt ttaagcatgg ctacgctcca catcgataac taatgatggc
     5041 gctggttgca taatatcgtg atggatagtg cgcaactctt cagtcaaaac caccagagga
     5101 ggcacatgat gatcacgttc aagcagcaaa ggacggctac cttgttgagc gtaagcataa
     5161 cgagccaagt caatcacctc ttgttgtact ggtttgccat gggtatcgag caagaaatct
     5221 tcgcgctctt ttaagtgacc tgcgatgtgg taatagcaga tcgcttcgct cggtaaagtg
     5281 gccagcatgt caaacgggca gtaattgtgg ttacggctat tcacatacac attattgata
     5341 tcaatcagca gctggcagcc gctgcgctca actatctcag taataaattc gccttcgggg
     5401 atctccttgc cgtaactgtg gtagtaggag atgttttcca gcaccaaagg acgttgcaca
     5461 atatcttgaa cgcagtgaat gcgatcgacc aagtaagcaa tgctctcttt atagcgcggg
     5521 ataggcagca gttcatacaa gtacccttgg gcatcacgcg aaaagctcaa atgctcactg
     5581 taaatgtcga tgttaaattc atctaaaaat gccgctacct ttttcacaaa cgctttgttc
     5641 agtggctgac aatcgccaat cgacaaactc agcccatgtg caaccagagg atagtgcttt
     5701 gctatctgct gtaactgctc gcgtttaagt ccgcccatgt tcatccagtt ctccggagca
     5761 agctcaagga aatcgatgtc gggatggtca ggcaactggc atagcaaatc gatgtgttcg
     5821 ctacgcaagc cgatgccttt tgaagtgcga tctattgccc gcatacacca ccagtgattt
     5881 tgctgttggt tagagtaatg gtttcagcgg aaggtgcgat tccctctgcg gttaagccac
     5941 atttaccatc tctggcgcgt actaaacgtc cttgcggatc gctttttaga tcctgtttct
     6001 caaagcgttt ttcagtacca catttgccag ccgcgcattt gccaccattt tgagaggtgg
     6061 gttgcgcact cactggtgct tccgttgacg tttctgcaac gctcattgca ggatgaagag
     6121 caatggccga agtcatcgca atagacaaaa caattttaca attcatgggt tatctccttc
     6181 acggaactca ttgggtagct tgagagatca cgggcggcaa taacttcgcc gtgataaaac
     6241 tgtttgatga tcttggtgga ctctgattta tgtttaaggc cgactcccat ccagtggttg
     6301 agcacgagca gtttaggatt gattttggct gcaatttcgc caatcactga aggtttagcg
     6361 tgcataaatg cggaaacttc atcggctgac tcatgaacag ccatcggcat gactaaaatg
     6421 tcagcgcctt gagcaaaatc gagaaatgct gggttactgc cgttttgatc ggcagaaatg
     6481 acaataacgc cctgatcact ttcaatacga taagccaaac atggcacgtc cccatgagga
     6541 ataccgagtg cgtaaatggt taaaccgtct tgttgataca ctttagttgg tgtcgtggtt
     6601 ttgtaagaaa catcagtgat ggtgactggg aacaaaccat cgctgccatc atacaaaccg
     6661 ttcaaataag cataagcgcc atctttgcta ttaaagagtg cgtccatata gcctgatagg
     6721 ctagggaagg ctgatcccgc ttgcgggcct gcaatatcta gtgggtcttc tcgcttaaag
     6781 aagtagccgc ctttgagcag cgcgggcaag tctgcaacgt ggtcggtgtg aaaatgggta
     6841 atgcctagaa aatccaaatc ttccagttta gagccggatt ggccaaagcg cagatacgca
     6901 ccgccgccag catcaatcat gattttagat ttgcctttcc accaaatcac ttccgctgaa
     6961 gaagagcgca gatcatctga aattggccct cccgatccta aaacttgtaa agtgaattct
     7021 ttgtcgagcg gttctaacga gtttgcgtaa gcaccgatgg caccgcacga caaactgatt
     7081 gcgagcacca gcgccttgag tggttgtttc atgctgacta ccttttgatt gtctttttta
     7141 tgatatgtgg atacctaggg cgaaaagaga cttgcgataa aagtgcaagc tttttgattc
     7201 tcgtcaaggt gtaggtgaaa gatatgattt acgaggatgt ttggtcaatc ttgattttct
     7261 tacctattgg ttaaggtaaa ttgaacaatg tggtgtgatg caatgataag cctgttagat
     7321 tctaggtttg caccgcatag ccagaaccaa ttaatacaca taaaaaaata acaaatgttc
     7381 tatttagaac ggcatcactc cagtgttcag tgatatttaa cccacgttta cttttaagtg
     7441 atgttatttt tgggtggttt tgaatagggt aaagctattg ttttttacaa atacttatga
     7501 tgtcagtaat gtttatgatg aagatgaagc caagctatta cgtgattcct atgcttattg
     7561 catttaatgt ccatgcggct gacagtcagt gtgatgtgat ttccagccag ttacacgatg
     7621 tgagcaatgg ctctgaagcg gttgaacatt ctggcgggta cagcgttcgt gacaatccgc
     7681 ctattcgctg cgccgaggtc gtgtttaaga ccaaacagag ttacgacaaa gtggttgctt
     7741 ggatgaatga tgatttcacg gcgatttatg tcgatggttc agaagcaacg tccaatatgg
     7801 ttcgatttcg agaggatgat gtaaaagctg gctacgtgaa aatgaaggta aatcaaccaa
     7861 ttaccgctta tgtctgtttt ggtcaatcga gcgttccgat cagtcaaata gagtgcgata
     7921 taaaatagat tgcttaacaa tgtcaagtgc catctccctg aatgggagag caaatgatag
     7981 tcaggcctta tcctgacaaa gccatacatt tcgataccca atccttttct cattcaacgt
     8041 acaatcgccg cacttaatta ttgaaaaggg ttgttgtaac gatgtcagca aaatttgtac
     8101 tctcacccat tatgggtttg atggtttgtt tgggtatgca tacaccaaca gtattggctg
     8161 agtcagtcgc ttgggatcaa gctggtcagc aatggcagac tcaacaatcg caacatttta
     8221 tcgtgcactt tcgcagtgaa ttggcccagt acgcggcgcg ttcgttagat attgccgaga
     8281 aagtgcatca agatcttgcc agtcaattct caaagatgcc agctgaaaaa acgcacctaa
     8341 cgctggtgga tgactacgac tattccaacg gttgggcaac gccgctgcct tatgctcaaa
     8401 ttcgcttgat cttaaatcct cccagcgatg ttaatggatt ggaaggcaat gatgaatggt
     8461 tgcacatgct catccgccat gagtacactc acattgttca tatggaatta aatgagcgtg
     8521 cggtcactgg agctcgacgt atttttggcc gtcacacact gcttttcccg catgcaatga
     8581 caccctcgat gctgttagag gggttagcgg tttacatgga aagccaaaat gaacaaggtt
     8641 atggacgttt gcacaatagc cattttgcga tgcaaatgcg catggaagtg gcgagcgggc
     8701 aactagctga tctcaaccaa atcgtggtag cgaacaaacg tttgccgctt ggcagtaatt
     8761 acctctacgg cgcgtatttt attgattatt tagccaaaac gtatggcgaa gacgcactcc
     8821 aacatttttt aagcgattac agtggctacc taattccggg cgttttctta aaccgaagcg
     8881 ctcaacgtgc ttttggtaaa gacttctttg cgctttggca agagtttcgt gccgatctaa
     8941 tcacgcagtt ttcagatcaa attgtgcaaa gtaaggaaca gccttcggag gctcaatctc
     9001 tcgatagcca gccgtttgaa tatctattag ccaatggtgg atcagagcaa ttactggctt
     9061 ggcgtcgtga tggggttgat cgagcaaatt tagcgatgtg ggatagtaag caaaatcaat
     9121 ggcagcgttt attgactaca aaaagcttaa ctagcctcga tgttcatccc cagcaaggta
     9181 tcgtcgcgtc acaagtgaat agttatcttg atggacgagt gttgaatgat ctttatcgct
     9241 acgttgatgg gcagtggcag cgtttaaccg agcaacagcg ctttacccaa gtacgttgga
     9301 gccgagatgg gcaaagtgtt ttcgctaccc gtcatgaaca agggttgcct gaattatggc
     9361 aggtgacgct ggatggacag caaactcgct tatggcaagg cacatatggt tgggtcattg
     9421 gtgatatggc gctgtctccg actggcgaca tttatgcttc cgtgaagcag ccgtctagcg
     9481 cttggaatat catgcgtttt gtcgccaaag agcagcgctg gttggctgtc actgaaacat
     9541 cagcaaccga gcatcaattg agttttaccc aagagggtga gttgctgttc agcgccgatt
     9601 acacggggcg ttatcagatc taccgaatgg acttggccag tttgcagttg gagcagttaa
     9661 ccaatgaaat tggaggtgct ttttctccgc aatggaatca atcgcaaggg cttatctacc
     9721 aagcttatga gcatgatggt taccatttgc gccacattcc gacggtgacg gctttcaatg
     9781 aggctccgct gtcttccttt gccaaggtga cggccgttac ttcgacgccg atatctcagg
     9841 ccgaaaaaag tgacactacc gactactcac cgttgtcgac cttaacgcca cgttattggg
     9901 ttcccgtttg gcaaggggat gataaccaat cgttatttgg tttctcgacc agtggttcag
     9961 atgtgttagg gcgacatcaa tatgagatcc aagcggcttg ggatacaaaa aatgcgttgg
    10021 cgacgtacca attggggtat caatatgaca accgttggca agcgacgctc agccgagagc
    10081 atgagtttaa gttaaaccca ttgaccaata aagacgatcg cattgtccgt caagatgact
    10141 taacgttaca acgtaattat ttatggcatg gcctcgatga taacttaatg tttggtatcg
    10201 gaacttattg gcagaaagag tcattgatca aagcgcctca aggtacgcgc tatacacaag
    10261 ccagtgatga gtggctagca ggggctgcgc tacaatggga taaccgtgaa ggcttattga
    10321 atgttcccgg ttacgcgtgg ggtcattacg ctgatttggt atgggagtcc aatgttggcg
    10381 gtgattactc tggacaaaaa tggcaggcgc agtggcaagc acattgggac ctcccgggga
    10441 gcttcaacct taccactcat cttgcggcag gttatgcgga ctcaaaagcc aaacggtttg
    10501 agctgggcag ttacgaaggt gacagcgcgc agctctatgg ccgccaacag atagcgttgc
    10561 gtggctacag ctctgcggct caagtagggc aagcttacgc gacacaaagt gttgaactaa
    10621 gccgcttatt gtatcgcgct gaacgaaact ggaatttgtg gccaattggc ttgggggata
    10681 tttcaggttc tgtatttgtc gactcaggat caagctggaa cgataaccaa aactaccaag
    10741 ccctgacggg gattggtgct gaagtgcaga tcgataccat cgtactttat ggcggcacgt
    10801 taccagtacg gattggttac gctcatggat tagacagtaa attaggcaaa gatgaagtgt
    10861 atgt
//
