LOCUS       NC_013961.1            20282 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_013961.1 Erwinia amylovora CFBP1430, complete sequence.
ACCESSION   NC_013961
VERSION     NC_013961.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:32:14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3161666
            Orig. end    :: 3181948
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20282
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[3171666:3171948](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10282)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20282
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20282
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="3"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(195..1160)
                     /locus_tag="ctg1_2806"
                     /transl_table=11
                     /translation="MREKLLQAARETIATELSGAMNLAARLDDHFVQACEMMRACRGKA
                     IVSGIGKSGHIGKKIAATLASTGTPAFYVHPAEALHGDLGMIAAGDVVILISYSGFAAE
                     FIRMVPMLKRLPVGIIAFTGKPTSPLAMAADQVINIHTDREACPLGLAPTSSAVNTLIM
                     GDALAIALMRSRNFSEHDYARTHPGGSLGTRLLCCVGDIMRKGEKLPRITRDVTVGDAL
                     AELTRTGLGLVAVTDDAGVLIGVFTDGDLRRWLHKGENIQAGISRVMTVGSKTLNAGQL
                     ATEALAMFHEQKISAAPVVDEQGRVTGAINLHDIHDAGIF"
     PFAM_domain     complement(216..362)
                     /aSDomain="CBS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00571.30"
                     /description="CBS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2806_0137"
                     /evalue="7.10E-05"
                     /label="ctg1_2806"
                     /locus_tag="ctg1_2806"
                     /protein_end="315"
                     /protein_start="266"
                     /score="23.3"
                     /tool="antismash"
                     /translation="RVMTVGSKTLNAGQLATEALAMFHEQKISAAPVVDEQGRVTGAIN
                     LHDI"
     aSDomain        complement(228..1034)
                     /aSDomain="TIGR00393"
                     /aSTool="tigrfam"
                     /description="kpsF: sugar isomerase, KpsF/GutQ family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2806_0037"
                     /evalue="6.90E-108"
                     /identifier="TIGR00393"
                     /label="ctg1_2806"
                     /locus_tag="ctg1_2806"
                     /protein_end="311"
                     /protein_start="42"
                     /score="358.2"
                     /tool="antismash"
                     /translation="GKAIVSGIGKSGHIGKKIAATLASTGTPAFYVHPAEALHGDLGMI
                     AAGDVVILISYSGFAAEFIRMVPMLKRLPVGIIAFTGKPTSPLAMAADQVINIHTDREA
                     CPLGLAPTSSAVNTLIMGDALAIALMRSRNFSEHDYARTHPGGSLGTRLLCCVGDIMRK
                     GEKLPRITRDVTVGDALAELTRTGLGLVAVTDDAGVLIGVFTDGDLRRWLHKGENIQAG
                     ISRVMTVGSKTLNAGQLATEALAMFHEQKISAAPVVDEQGRVTGAIN"
     PFAM_domain     complement(393..566)
                     /aSDomain="CBS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00571.30"
                     /description="CBS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2806_0136"
                     /evalue="2.90E-08"
                     /label="ctg1_2806"
                     /locus_tag="ctg1_2806"
                     /protein_end="256"
                     /protein_start="198"
                     /score="34.1"
                     /tool="antismash"
                     /translation="VGDIMRKGEKLPRITRDVTVGDALAELTRTGLGLVAVTDDAGVLI
                     GVFTDGDLRRWLH"
     PFAM_domain     complement(651..1040)
                     /aSDomain="SIS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01380.24"
                     /description="SIS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2806_0135"
                     /evalue="2.30E-29"
                     /label="ctg1_2806"
                     /locus_tag="ctg1_2806"
                     /protein_end="170"
                     /protein_start="40"
                     /score="101.9"
                     /tool="antismash"
                     /translation="CRGKAIVSGIGKSGHIGKKIAATLASTGTPAFYVHPAEALHGDLG
                     MIAAGDVVILISYSGFAAEFIRMVPMLKRLPVGIIAFTGKPTSPLAMAADQVINIHTDR
                     EACPLGLAPTSSAVNTLIMGDALAIA"
     CDS             complement(1165..1932)
                     /locus_tag="ctg1_2807"
                     /transl_table=11
                     /translation="MKPIQRQAQILEFLQRNGRTTVDQLIVRFNTTGTTIRKDLTHLQQ
                     EGAVIRTYGGVMLNREEGDQPLDRKTLINTEKKKHIARRAAELINEGDSLIFDAGSTVL
                     QMVPYLARFNNITVMTNSLTIVNQLVEHDSDRVVLMPGGTYRRNSASFHGSVAESAFSH
                     FNFDTLFIGADGVDLTAGVTTFNEVFSVSQAMCRAAKKIVLLVDSSKFGRKSPNVVCSL
                     DAVDVLITDNAISPDIVKQLSGMNISVITAGED"
     PFAM_domain     complement(1237..1713)
                     /aSDomain="DeoRC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00455.24"
                     /description="DeoR C terminal sensor domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2807_0139"
                     /evalue="6.60E-51"
                     /label="ctg1_2807"
                     /locus_tag="ctg1_2807"
                     /protein_end="232"
                     /protein_start="73"
                     /score="172.6"
                     /tool="antismash"
                     /translation="NTEKKKHIARRAAELINEGDSLIFDAGSTVLQMVPYLARFNNITV
                     MTNSLTIVNQLVEHDSDRVVLMPGGTYRRNSASFHGSVAESAFSHFNFDTLFIGADGVD
                     LTAGVTTFNEVFSVSQAMCRAAKKIVLLVDSSKFGRKSPNVVCSLDAVDVLITDN"
     PFAM_domain     complement(1753..1917)
                     /aSDomain="HTH_DeoR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08220.14"
                     /description="DeoR-like helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2807_0138"
                     /evalue="7.60E-15"
                     /label="ctg1_2807"
                     /locus_tag="ctg1_2807"
                     /protein_end="60"
                     /protein_start="5"
                     /score="54.5"
                     /tool="antismash"
                     /translation="RQAQILEFLQRNGRTTVDQLIVRFNTTGTTIRKDLTHLQQEGAVI
                     RTYGGVMLNR"
     CDS             complement(2025..2387)
                     /locus_tag="ctg1_2808"
                     /transl_table=11
                     /translation="MDATNTLILLAVTAWVGQILLGWFQIQNFNRALAALGQTGQVVIG
                     RSGGRFKPRVVLALSLDEEQRVTDNFVMKGVTIFARPANEPKLNGLCLNEIQPQILFPK
                     SAATQQALALAISHKG"
     PFAM_domain     complement(2052..2369)
                     /aSDomain="GutM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06923.13"
                     /description="Glucitol operon activator protein (GutM)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2808_0140"
                     /evalue="8.20E-32"
                     /label="ctg1_2808"
                     /locus_tag="ctg1_2808"
                     /protein_end="112"
                     /protein_start="6"
                     /score="109.6"
                     /tool="antismash"
                     /translation="LILLAVTAWVGQILLGWFQIQNFNRALAALGQTGQVVIGRSGGRF
                     KPRVVLALSLDEEQRVTDNFVMKGVTIFARPANEPKLNGLCLNEIQPQILFPKSAATQQ
                     AL"
     CDS             complement(2435..3214)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     176.4; E-value: 1.2e-53)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2809"
                     /transl_table=11
                     /translation="MEQVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADT
                     INSRYGAGRAYGFKVDATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTD
                     FDLSLQVNLVGYFLCSREFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVG
                     LTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLK
                     RGCDYQDVLNVLLFYASDKAAYCTGQSINVTGGQVMF"
     PFAM_domain     complement(2624..3208)
                     /aSDomain="adh_short"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00106.27"
                     /description="short chain dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2809_0141"
                     /evalue="8.10E-47"
                     /label="ctg1_2809"
                     /locus_tag="ctg1_2809"
                     /protein_end="197"
                     /protein_start="2"
                     /score="159.3"
                     /tool="antismash"
                     /translation="QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTIN
                     SRYGAGRAYGFKVDATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFD
                     LSLQVNLVGYFLCSREFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLT
                     QSLALDLAEYGITVHSLMLGNLLKSPMFQSLL"
     CDS             complement(3229..3597)
                     /locus_tag="ctg1_2810"
                     /transl_table=11
                     /translation="MTIVYESTFVAVGTSACESLADDFLITFGEGAPEDIAEYCFIHRN
                     DINQGGLLGAGSMLTIGEQHYPVTAVGEVARENLRDLGHITVRFDGANHAEFPGSVHVT
                     GQPPLVIEPGQKFRVVSE"
     aSDomain        complement(3232..3597)
                     /aSDomain="TIGR00849"
                     /aSTool="tigrfam"
                     /description="gutA: PTS system, glucitol/sorbitol-specific
                     IIA component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2810_0038"
                     /evalue="8.50E-60"
                     /identifier="TIGR00849"
                     /label="ctg1_2810"
                     /locus_tag="ctg1_2810"
                     /protein_end="122"
                     /protein_start="0"
                     /score="197.9"
                     /tool="antismash"
                     /translation="MTIVYESTFVAVGTSACESLADDFLITFGEGAPEDIAEYCFIHRN
                     DINQGGLLGAGSMLTIGEQHYPVTAVGEVARENLRDLGHITVRFDGANHAEFPGSVHVT
                     GQPPLVIEPGQKFRVVSE"
     PFAM_domain     complement(3250..3585)
                     /aSDomain="PTSIIA_gutA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03829.15"
                     /description="PTS system glucitol/sorbitol-specific IIA
                     component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2810_0142"
                     /evalue="8.40E-34"
                     /label="ctg1_2810"
                     /locus_tag="ctg1_2810"
                     /protein_end="116"
                     /protein_start="4"
                     /score="116.0"
                     /tool="antismash"
                     /translation="YESTFVAVGTSACESLADDFLITFGEGAPEDIAEYCFIHRNDINQ
                     GGLLGAGSMLTIGEQHYPVTAVGEVARENLRDLGHITVRFDGANHAEFPGSVHVTGQPP
                     LVIEPGQK"
     CDS             complement(3612..4613)
                     /locus_tag="ctg1_2811"
                     /transl_table=11
                     /translation="MANTIEIRKGESGWGGPLSINVTAGKKIVYITAGTKPAIVDHLVA
                     LTGWEAVDGFKQGEPPAEEIGVAVIDCGGTLRCGLYPKRRIPTINIHATGKSGPLAQFI
                     TEDIYVSGVRVADIRVANDAEAAPPEVAVADVAVNAGKGTGRDYDTSKKITEQSDGLLA
                     KVGMGMGSAVAILFQSGRETIDTVLKTILPFMAFVSALIGIIMASGLGDFIAHGLTPLA
                     NSPVGLVTLALICSFPLLSPFLGPGAVIAQVIGVLVGVQIGQGTIPPHLALPALFAINA
                     QAACDFIPVGLSLANARQETVRVGVPAVLVGRFITGAPTVLLAWAASSFIYH"
     aSDomain        complement(3615..4607)
                     /aSDomain="TIGR00825"
                     /aSTool="tigrfam"
                     /description="EIIBC-GUT: PTS system,
                     glucitol/sorbitol-specific, IIBC component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2811_0039"
                     /evalue="8.80E-198"
                     /identifier="TIGR00825"
                     /label="ctg1_2811"
                     /locus_tag="ctg1_2811"
                     /protein_end="333"
                     /protein_start="2"
                     /score="654.0"
                     /tool="antismash"
                     /translation="NTIEIRKGESGWGGPLSINVTAGKKIVYITAGTKPAIVDHLVALT
                     GWEAVDGFKQGEPPAEEIGVAVIDCGGTLRCGLYPKRRIPTINIHATGKSGPLAQFITE
                     DIYVSGVRVADIRVANDAEAAPPEVAVADVAVNAGKGTGRDYDTSKKITEQSDGLLAKV
                     GMGMGSAVAILFQSGRETIDTVLKTILPFMAFVSALIGIIMASGLGDFIAHGLTPLANS
                     PVGLVTLALICSFPLLSPFLGPGAVIAQVIGVLVGVQIGQGTIPPHLALPALFAINAQA
                     ACDFIPVGLSLANARQETVRVGVPAVLVGRFITGAPTVLLAWAASSFIYH"
     PFAM_domain     complement(3618..3896)
                     /aSDomain="EIIBC-GUT_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07663.13"
                     /description="Sorbitol phosphotransferase enzyme II
                     C-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2811_0144"
                     /evalue="1.40E-41"
                     /label="ctg1_2811"
                     /locus_tag="ctg1_2811"
                     /protein_end="332"
                     /protein_start="239"
                     /score="140.7"
                     /tool="antismash"
                     /translation="LSPFLGPGAVIAQVIGVLVGVQIGQGTIPPHLALPALFAINAQAA
                     CDFIPVGLSLANARQETVRVGVPAVLVGRFITGAPTVLLAWAASSFIY"
     PFAM_domain     complement(4059..4601)
                     /aSDomain="EIIBC-GUT_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03612.16"
                     /description="Sorbitol phosphotransferase enzyme II
                     N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2811_0143"
                     /evalue="2.00E-66"
                     /label="ctg1_2811"
                     /locus_tag="ctg1_2811"
                     /protein_end="185"
                     /protein_start="4"
                     /score="223.3"
                     /tool="antismash"
                     /translation="IEIRKGESGWGGPLSINVTAGKKIVYITAGTKPAIVDHLVALTGW
                     EAVDGFKQGEPPAEEIGVAVIDCGGTLRCGLYPKRRIPTINIHATGKSGPLAQFITEDI
                     YVSGVRVADIRVANDAEAAPPEVAVADVAVNAGKGTGRDYDTSKKITEQSDGLLAKVGM
                     GMGSAVAILFQSGRETID"
     CDS             complement(4629..5177)
                     /locus_tag="ctg1_2812"
                     /transl_table=11
                     /translation="MIEAITHGAEWFIGLFQKGGEVFVGMVTGILPLLISLLVIMNALI
                     VFVGQRRIEKLAQKCAGNPVTRYLVLPFIGTFVFCNPMTHSLGKFLPEKYKPSYYAAAS
                     YSCHSMNGLFPHINPGELFVYLGIANGLTTLGVPLGPLAVSYLLVGLITNFFRGWVTDL
                     TTSVFEKKMGIKLDKSVHL"
     aSDomain        complement(4635..5177)
                     /aSDomain="TIGR00821"
                     /aSTool="tigrfam"
                     /description="EII-GUT: PTS system,
                     glucitol/sorbitol-specific, IIC component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2812_0040"
                     /evalue="1.40E-112"
                     /identifier="TIGR00821"
                     /label="ctg1_2812"
                     /locus_tag="ctg1_2812"
                     /protein_end="181"
                     /protein_start="0"
                     /score="371.7"
                     /tool="antismash"
                     /translation="MIEAITHGAEWFIGLFQKGGEVFVGMVTGILPLLISLLVIMNALI
                     VFVGQRRIEKLAQKCAGNPVTRYLVLPFIGTFVFCNPMTHSLGKFLPEKYKPSYYAAAS
                     YSCHSMNGLFPHINPGELFVYLGIANGLTTLGVPLGPLAVSYLLVGLITNFFRGWVTDL
                     TTSVFEKKMGIKLDKSVH"
     PFAM_domain     complement(4665..5162)
                     /aSDomain="EII-GUT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03608.15"
                     /description="PTS system enzyme II sorbitol-specific
                     factor"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2812_0145"
                     /evalue="7.10E-74"
                     /label="ctg1_2812"
                     /locus_tag="ctg1_2812"
                     /protein_end="171"
                     /protein_start="5"
                     /score="247.3"
                     /tool="antismash"
                     /translation="THGAEWFIGLFQKGGEVFVGMVTGILPLLISLLVIMNALIVFVGQ
                     RRIEKLAQKCAGNPVTRYLVLPFIGTFVFCNPMTHSLGKFLPEKYKPSYYAAASYSCHS
                     MNGLFPHINPGELFVYLGIANGLTTLGVPLGPLAVSYLLVGLITNFFRGWVTDLTTSVF
                     EKK"
     CDS             complement(5930..6163)
                     /locus_tag="ctg1_2813"
                     /transl_table=11
                     /translation="MKISIRTTWIAVFIFCVLLLALIFVSLIRVANDIKKALQQPVQDD
                     PNKLAEQLKKLKLNEKQKKFIESLIKNDEKKQ"
     CDS             complement(6472..8862)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2814"
                     /sec_met_domain="Peptidase_M16 (E-value: 7.7e-30, bitscore:
                     101.5, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1.3e-07,
                     bitscore: 29.4, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPQRRRLDNGLRVVLISDAQAVQAAALFQVDTGSHYEPDSWPGL
                     AHLLEHLLFAGSCAYADDERLMAWLPARGGRLNATTQGSSTAFFFECDAGLLAPGLARL
                     SDMLLAPLLAENAIRQEVATIDAECRLLAGQQDTLCNAAQSMAFAAHPWQRFHIGNAAS
                     FTGDWPALRLALQQFHQRYYHAANITLWLQGPQSPEALWQLARQYGSAFSAVGVPPPAL
                     PLLHYSSQPDMALQLAGSPRLRLSFLLDRPRSNELTLLRQLLLDEAAGGLMATLRAHHL
                     CDGARLLVPYHSAMQTLVSVELALIDEQQAAEVEGWVHHWLQRLTALTARQRQHYMRLA
                     DFQFARLSPMDQLREHAVGFAPPQVQQDDWPGFCARLSVARLARLWIGAQSLAQQCSVQ
                     GFRLRCAAQTRAPVTALIPAEALTFFCESQPDAQAALPAGQVALNHQRAGKGRAALLLS
                     PLDELHAPWGVILQSRLRALAADCAHKGGDLSVSCQQGHWLIQLCGSPALMVRTLATLI
                     RQLCEISPVMIALGERQYQRQQQAQREGIAVRALIDALPALLRSSVYQPAGRRLPRLAW
                     QAVLDGGDDALRQSLSQLLSAFPGTINPPGRMQPEPLAPQPEYQVATISHDATLLRFCP
                     LVENSTQCLAAWQLLALIYQPAFFQRLRVEQNIGYVVSCRFYQAAGRSGLLFALQSPHL
                     STGELSAHIDRFLPGMDDELAALSMETVREKGAALLAQQRLAASDFQQECRQRWLAAQQ
                     SVPQPDEYVIQGLTPERLSDYHQRLLSDRHNAWTLVGIPANRF"
     aSDomain        complement(6742..8841)
                     /aSDomain="TIGR02110"
                     /aSTool="tigrfam"
                     /description="PQQ_syn_pqqF: coenzyme PQQ biosynthesis
                     protein PqqF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2814_0041"
                     /evalue="5.40E-149"
                     /identifier="TIGR02110"
                     /label="ctg1_2814"
                     /locus_tag="ctg1_2814"
                     /protein_end="707"
                     /protein_start="7"
                     /score="496.0"
                     /tool="antismash"
                     /translation="LDNGLRVVLISDAQAVQAAALFQVDTGSHYEPDSWPGLAHLLEHL
                     LFAGSCAYADDERLMAWLPARGGRLNATTQGSSTAFFFECDAGLLAPGLARLSDMLLAP
                     LLAENAIRQEVATIDAECRLLAGQQDTLCNAAQSMAFAAHPWQRFHIGNAASFTGDWPA
                     LRLALQQFHQRYYHAANITLWLQGPQSPEALWQLARQYGSAFSAVGVPPPALPLLHYSS
                     QPDMALQLAGSPRLRLSFLLDRPRSNELTLLRQLLLDEAAGGLMATLRAHHLCDGARLL
                     VPYHSAMQTLVSVELALIDEQQAAEVEGWVHHWLQRLTALTARQRQHYMRLADFQFARL
                     SPMDQLREHAVGFAPPQVQQDDWPGFCARLSVARLARLWIGAQSLAQQCSVQGFRLRCA
                     AQTRAPVTALIPAEALTFFCESQPDAQAALPAGQVALNHQRAGKGRAALLLSPLDELHA
                     PWGVILQSRLRALAADCAHKGGDLSVSCQQGHWLIQLCGSPALMVRTLATLIRQLCEIS
                     PVMIALGERQYQRQQQAQREGIAVRALIDALPALLRSSVYQPAGRRLPRLAWQAVLDGG
                     DDALRQSLSQLLSAFPGTINPPGRMQPEPLAPQPEYQVATISHDATLLRFCPLVENSTQ
                     CLAAWQLLALIYQPAFFQRLRVEQNIGYVVSCRFYQAAGRSGLLFALQSPHLSTGELSA
                     HIDRFL"
     PFAM_domain     complement(7894..8340)
                     /aSDomain="Peptidase_M16_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05193.23"
                     /description="Peptidase M16 inactive domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2814_0147"
                     /evalue="1.40E-06"
                     /label="ctg1_2814"
                     /locus_tag="ctg1_2814"
                     /protein_end="323"
                     /protein_start="174"
                     /score="28.6"
                     /tool="antismash"
                     /translation="LQQFHQRYYHAANITLWLQGPQSPEALWQLARQYGSAFSAVGVPP
                     PALPLLHYSSQPDMALQLAGSPRLRLSFLLDRPRSNELTLLRQLLLDEAAGGLMATLRA
                     HHLCDGARLLVPYHSAMQTLVSVELALIDEQQAAEVEGWVHHWLQ"
     PFAM_domain     complement(8476..8826)
                     /aSDomain="Peptidase_M16"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00675.22"
                     /description="Insulinase (Peptidase family M16)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2814_0146"
                     /evalue="3.90E-27"
                     /label="ctg1_2814"
                     /locus_tag="ctg1_2814"
                     /protein_end="129"
                     /protein_start="12"
                     /score="95.2"
                     /tool="antismash"
                     /translation="RVVLISDAQAVQAAALFQVDTGSHYEPDSWPGLAHLLEHLLFAGS
                     CAYADDERLMAWLPARGGRLNATTQGSSTAFFFECDAGLLAPGLARLSDMLLAPLLAEN
                     AIRQEVATIDAEC"
     CDS             complement(8866..10014)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2815"
                     /sec_met_domain="PF04055 (E-value: 2.5e-23, bitscore: 80.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.3e-06, bitscore: 26.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNPAESPIKPPLWLLAELTYRCPLQCPYCSNPLDFARQEKELTTA
                     QWIDVFKQARAMGAVQIGFSGGEPLVRNDLPELIRSARDLGFYTNLITSGIGLTQKKID
                     AFAEAGLDHIQISFQASDETLNAALAGSTKAFQQKLEMARAVKAHGYPMVLNFVLHRHN
                     IDQLDRIIELCIELEADDVELATCQFYGWAQLNREGLLPTRDQLARAEAVVHHYREKMA
                     ASGNLANLLFVTPDYYEERPKGCMGGWGAIFLSVTPEGMALPCHSARQLPIPFPSVLEH
                     SLQDIWFNSFGFNRYRGFDWMPEPCRSCDEKEKDFGGCRCQAFMLTGNADNADPVCSKS
                     EHHGTILAAREQANCSHIQVNQLRFRNRANSQRVNAQLIFKG"
     aSDomain        complement(8917..9993)
                     /aSDomain="TIGR02109"
                     /aSTool="tigrfam"
                     /description="PQQ_syn_pqqE: coenzyme PQQ biosynthesis
                     enzyme PqqE"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2815_0042"
                     /evalue="4.60E-185"
                     /identifier="TIGR02109"
                     /label="ctg1_2815"
                     /locus_tag="ctg1_2815"
                     /protein_end="366"
                     /protein_start="7"
                     /score="612.6"
                     /tool="antismash"
                     /translation="IKPPLWLLAELTYRCPLQCPYCSNPLDFARQEKELTTAQWIDVFK
                     QARAMGAVQIGFSGGEPLVRNDLPELIRSARDLGFYTNLITSGIGLTQKKIDAFAEAGL
                     DHIQISFQASDETLNAALAGSTKAFQQKLEMARAVKAHGYPMVLNFVLHRHNIDQLDRI
                     IELCIELEADDVELATCQFYGWAQLNREGLLPTRDQLARAEAVVHHYREKMAASGNLAN
                     LLFVTPDYYEERPKGCMGGWGAIFLSVTPEGMALPCHSARQLPIPFPSVLEHSLQDIWF
                     NSFGFNRYRGFDWMPEPCRSCDEKEKDFGGCRCQAFMLTGNADNADPVCSKSEHHGTIL
                     AAREQANCSHIQVNQLRFR"
     PFAM_domain     complement(9085..9282)
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2815_0149"
                     /evalue="3.40E-06"
                     /label="ctg1_2815"
                     /locus_tag="ctg1_2815"
                     /protein_end="310"
                     /protein_start="244"
                     /score="27.5"
                     /tool="antismash"
                     /translation="CMGGWGAIFLSVTPEGMALPCHSARQLPIPFPSVLEHSLQDIWFN
                     SFGFNRYRGFDWMPEPCRSCD"
     PFAM_domain     complement(9496..9963)
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2815_0148"
                     /evalue="2.10E-22"
                     /label="ctg1_2815"
                     /locus_tag="ctg1_2815"
                     /protein_end="173"
                     /protein_start="17"
                     /score="80.4"
                     /tool="antismash"
                     /translation="LTYRCPLQCPYCSNPLDFARQEKELTTAQWIDVFKQARAMGAVQI
                     GFSGGEPLVRNDLPELIRSARDLGFYTNLITSGIGLTQKKIDAFAEAGLDHIQISFQAS
                     DETLNAALAGSTKAFQQKLEMARAVKAHGYPMVLNFVLHRHNIDQLDRIIEL"
     CDS             complement(10001..10282)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2816"
                     /sec_met_domain="PF05402 (E-value: 5.2e-13, bitscore: 46.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2e-32, bitscore: 108.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKCDQRIPIFRRGYRLQWEEMQNCHVILYPEGMAKLNDSATMILE
                     LVDGQRSLADIARTLNVRFPDAGGVDDDVTDFFAAAREQKWIIFREPS"
     PFAM_domain     complement(10022..10213)
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2816_0150"
                     /evalue="8.50E-12"
                     /label="ctg1_2816"
                     /locus_tag="ctg1_2816"
                     /protein_end="87"
                     /protein_start="23"
                     /score="45.3"
                     /tool="antismash"
                     /translation="CHVILYPEGMAKLNDSATMILELVDGQRSLADIARTLNVRFPDAG
                     GVDDDVTDFFAAAREQKWI"
     aSDomain        complement(10022..10261)
                     /aSDomain="TIGR03859"
                     /aSTool="tigrfam"
                     /description="PQQ_PqqD: coenzyme PQQ biosynthesis protein
                     PqqD"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2816_0043"
                     /evalue="9.80E-36"
                     /identifier="TIGR03859"
                     /label="ctg1_2816"
                     /locus_tag="ctg1_2816"
                     /protein_end="87"
                     /protein_start="7"
                     /score="119.5"
                     /tool="antismash"
                     /translation="PIFRRGYRLQWEEMQNCHVILYPEGMAKLNDSATMILELVDGQRS
                     LADIARTLNVRFPDAGGVDDDVTDFFAAAREQKWI"
     CDS             complement(10279..11034)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR02111"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2817"
                     /sec_met_domain="TIGR02111 (E-value: 6.2e-115, bitscore:
                     380.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPALMTPQQFEQALRARGAYYHIHHPYHIAMHNGEATREQIQG
                     WVANRYYYQTRIPLKDAAIMANCRDALTRRKWVQRILDHDGQGDSEGGIEAWLRLGEAV
                     GLDRDVLQSEQRVLPGVRFAVDAYVSFARRAVWQEAACSSLTELYAPEIHQSRLNSWPQ
                     HYPWIEEEGYGYFRGRLGQARRDVEHGLQLALEYCNSVEKQQRMLEILQFKLDILWSML
                     DAMTMAYTLNRAPYHTVTDQPVWHKGNLL"
     aSDomain        complement(10312..11016)
                     /aSDomain="TIGR02111"
                     /aSTool="tigrfam"
                     /description="PQQ_syn_pqqC: coenzyme PQQ biosynthesis
                     protein C"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2817_0044"
                     /evalue="8.30E-115"
                     /identifier="TIGR02111"
                     /label="ctg1_2817"
                     /locus_tag="ctg1_2817"
                     /protein_end="241"
                     /protein_start="6"
                     /score="380.2"
                     /tool="antismash"
                     /translation="MTPQQFEQALRARGAYYHIHHPYHIAMHNGEATREQIQGWVANRY
                     YYQTRIPLKDAAIMANCRDALTRRKWVQRILDHDGQGDSEGGIEAWLRLGEAVGLDRDV
                     LQSEQRVLPGVRFAVDAYVSFARRAVWQEAACSSLTELYAPEIHQSRLNSWPQHYPWIE
                     EEGYGYFRGRLGQARRDVEHGLQLALEYCNSVEKQQRMLEILQFKLDILWSMLDAMTMA
                     YTLNRAPYHTVTD"
     PFAM_domain     complement(10366..10986)
                     /aSDomain="TENA_THI-4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03070.18"
                     /description="TENA/THI-4/PQQC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2817_0151"
                     /evalue="4.50E-61"
                     /label="ctg1_2817"
                     /locus_tag="ctg1_2817"
                     /protein_end="223"
                     /protein_start="16"
                     /score="206.4"
                     /tool="antismash"
                     /translation="RARGAYYHIHHPYHIAMHNGEATREQIQGWVANRYYYQTRIPLKD
                     AAIMANCRDALTRRKWVQRILDHDGQGDSEGGIEAWLRLGEAVGLDRDVLQSEQRVLPG
                     VRFAVDAYVSFARRAVWQEAACSSLTELYAPEIHQSRLNSWPQHYPWIEEEGYGYFRGR
                     LGQARRDVEHGLQLALEYCNSVEKQQRMLEILQFKLDILWSMLD"
     CDS             complement(11031..11942)
                     /locus_tag="ctg1_2818"
                     /transl_table=11
                     /translation="MKIKVLGSAAGGGFPQWNCYCPNCQGVRNGSIRATARTQSSIAVS
                     DNGSDWVLCNASPDICHQIAANPELHPQGKLRGSGIGSIILTDSQIDHCTGLLNLREGC
                     PHHVWCTAEVHADLTSGFPIFTMLQHWNGGLVHHAIQLAQPFSVAVCPALRFTAIPILS
                     NAPPYSPYRGRPLPGHNIALMIENTASGSKLLYAPGLGEPDAQLLDLMSQADCLLVDGT
                     LWQDNELANTGVGRNTGRDMGHLALDEDRGLMALLGDLPAPRKILIHINNTNPILDESS
                     AERLALSARGIEVSYDGMSIEL"
     aSDomain        complement(11034..11939)
                     /aSDomain="TIGR02108"
                     /aSTool="tigrfam"
                     /description="PQQ_syn_pqqB: coenzyme PQQ biosynthesis
                     protein B"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2818_0045"
                     /evalue="8.00E-124"
                     /identifier="TIGR02108"
                     /label="ctg1_2818"
                     /locus_tag="ctg1_2818"
                     /protein_end="303"
                     /protein_start="1"
                     /score="410.6"
                     /tool="antismash"
                     /translation="KIKVLGSAAGGGFPQWNCYCPNCQGVRNGSIRATARTQSSIAVSD
                     NGSDWVLCNASPDICHQIAANPELHPQGKLRGSGIGSIILTDSQIDHCTGLLNLREGCP
                     HHVWCTAEVHADLTSGFPIFTMLQHWNGGLVHHAIQLAQPFSVAVCPALRFTAIPILSN
                     APPYSPYRGRPLPGHNIALMIENTASGSKLLYAPGLGEPDAQLLDLMSQADCLLVDGTL
                     WQDNELANTGVGRNTGRDMGHLALDEDRGLMALLGDLPAPRKILIHINNTNPILDESSA
                     ERLALSARGIEVSYDGMSIEL"
     PFAM_domain     complement(11133..11792)
                     /aSDomain="Lactamase_B_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12706.9"
                     /description="Beta-lactamase superfamily domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2818_0152"
                     /evalue="3.10E-40"
                     /label="ctg1_2818"
                     /locus_tag="ctg1_2818"
                     /protein_end="270"
                     /protein_start="50"
                     /score="138.0"
                     /tool="antismash"
                     /translation="WVLCNASPDICHQIAANPELHPQGKLRGSGIGSIILTDSQIDHCT
                     GLLNLREGCPHHVWCTAEVHADLTSGFPIFTMLQHWNGGLVHHAIQLAQPFSVAVCPAL
                     RFTAIPILSNAPPYSPYRGRPLPGHNIALMIENTASGSKLLYAPGLGEPDAQLLDLMSQ
                     ADCLLVDGTLWQDNELANTGVGRNTGRDMGHLALDEDRGLMALLGDLPAPRKILIHI"
     CDS             complement(12283..13332)
                     /locus_tag="ctg1_2819"
                     /transl_table=11
                     /translation="MTDSSPLNPVFDGHNDLLLHLWLNHPENPAEAFFNRRLSGHLDFS
                     RMRQGGFAGGLFAVFVPPSDYVATFHGRDAQQEALRHDALAITASQIAILQQLASQSGG
                     RAKICRSASEIEQCMAGGVLAMVMHIEGAAALDGDLSQLDRWVDAGLRSIGPFWNLPNR
                     FGFGVSGSFPGSPDSGEGLTAAGKQLIRLCNQRRLMVDVSHMNEKAFWDTARLSNAPLV
                     ASHSNVHTLCPQPRNLTDDQLAAIAYSDGLVGLNFGTAFLRSDGKRGGDMPLSVMVRHL
                     DYLLEKLGEDRVAFGSDFDGVHLADDIRDVSGLPRLLAVLRGAGYSEPLLAKLCRANWL
                     RILRKTWGN"
     PFAM_domain     complement(12301..13308)
                     /aSDomain="Peptidase_M19"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01244.23"
                     /description="Membrane dipeptidase (Peptidase family M19)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2819_0153"
                     /evalue="1.90E-89"
                     /label="ctg1_2819"
                     /locus_tag="ctg1_2819"
                     /protein_end="344"
                     /protein_start="8"
                     /score="300.0"
                     /tool="antismash"
                     /translation="PVFDGHNDLLLHLWLNHPENPAEAFFNRRLSGHLDFSRMRQGGFA
                     GGLFAVFVPPSDYVATFHGRDAQQEALRHDALAITASQIAILQQLASQSGGRAKICRSA
                     SEIEQCMAGGVLAMVMHIEGAAALDGDLSQLDRWVDAGLRSIGPFWNLPNRFGFGVSGS
                     FPGSPDSGEGLTAAGKQLIRLCNQRRLMVDVSHMNEKAFWDTARLSNAPLVASHSNVHT
                     LCPQPRNLTDDQLAAIAYSDGLVGLNFGTAFLRSDGKRGGDMPLSVMVRHLDYLLEKLG
                     EDRVAFGSDFDGVHLADDIRDVSGLPRLLAVLRGAGYSEPLLAKLCRANWLRILR"
     CDS             complement(13443..14921)
                     /locus_tag="ctg1_2820"
                     /transl_table=11
                     /translation="VNLQTLRRDIPAGLVVFLVALPLCLGIAQASGLPPFVGLLTGVVG
                     GLVVTTFSPSRFAVSGPAAGLVTIVTGAIETLGSFSALLLALIVAGVLQFSLGVVRAGR
                     FISLVPGSVIKGMLAAIGILLIIQQIPVALGAAGENDLASWLTGSALNISLPAMAVALS
                     GLLVLWLWTTSAVKKNRWLGWMPGPLMAVLLGCVATVLGGRLFPELASNLPRISLPAFD
                     SITSLAGELQRPDWMAWQNPAVYMVAVTLALVASLETLLSQEALQKIRLQHPAPSPDKE
                     LRAQGLGNALCGFLGGLPITAVIVRSSVNVGAGAQSKLSILIHGLLLLICGLWFSGLLN
                     AIPLASLAAVLLYTGYKLASPRLFVSQIRQGAQQSVPFLATVGGILIFGMLAGIAIGLI
                     TQVLFSTWRSQRNAMMLTQYDDHYVLRFQQNLNFMHNPRLKGLLAQIPENSVVIVDHDN
                     AEYLDPDVTAVLQEFGDEAQQRGIQLTHWPVKLA"
     PFAM_domain     complement(13842..14906)
                     /aSDomain="Sulfate_transp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00916.22"
                     /description="Sulfate permease family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2820_0154"
                     /evalue="3.60E-56"
                     /label="ctg1_2820"
                     /locus_tag="ctg1_2820"
                     /protein_end="360"
                     /protein_start="5"
                     /score="190.7"
                     /tool="antismash"
                     /translation="LRRDIPAGLVVFLVALPLCLGIAQASGLPPFVGLLTGVVGGLVVT
                     TFSPSRFAVSGPAAGLVTIVTGAIETLGSFSALLLALIVAGVLQFSLGVVRAGRFISLV
                     PGSVIKGMLAAIGILLIIQQIPVALGAAGENDLASWLTGSALNISLPAMAVALSGLLVL
                     WLWTTSAVKKNRWLGWMPGPLMAVLLGCVATVLGGRLFPELASNLPRISLPAFDSITSL
                     AGELQRPDWMAWQNPAVYMVAVTLALVASLETLLSQEALQKIRLQHPAPSPDKELRAQG
                     LGNALCGFLGGLPITAVIVRSSVNVGAGAQSKLSILIHGLLLLICGLWFSGLLNAIPLA
                     SLAAVLLYTGYKLAS"
     CDS             complement(14918..15544)
                     /locus_tag="ctg1_2821"
                     /transl_table=11
                     /translation="LRTLKPLLAKNRSWALQRQQRHPQYFQQNAEGQQPHSLWIGCSDS
                     RVPAEVLTNSHPGELFVHRNIANMVVSNDDNFMSVLQYAIEYLQVSRIVLCGHYGCGGV
                     QAALTLPDLPLNDENSALARRITLLREALSVQLAAPNAQEDDVARLNRLVEANVLAQFS
                     QLVQTVPVVNAWRKGADLDVFGCVYDLHSGHLKELVQQQSEGGCT"
     PFAM_domain     complement(14963..15433)
                     /aSDomain="Pro_CA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00484.21"
                     /description="Carbonic anhydrase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2821_0155"
                     /evalue="1.00E-44"
                     /label="ctg1_2821"
                     /locus_tag="ctg1_2821"
                     /protein_end="194"
                     /protein_start="37"
                     /score="152.7"
                     /tool="antismash"
                     /translation="LWIGCSDSRVPAEVLTNSHPGELFVHRNIANMVVSNDDNFMSVLQ
                     YAIEYLQVSRIVLCGHYGCGGVQAALTLPDLPLNDENSALARRITLLREALSVQLAAPN
                     AQEDDVARLNRLVEANVLAQFSQLVQTVPVVNAWRKGADLDVFGCVYDLHSGH"
     CDS             complement(16055..16312)
                     /locus_tag="ctg1_2822"
                     /transl_table=11
                     /translation="MTSLFSPENQRKPISGAVRGIGLLMAQGLAQQRCVMPPANRALAL
                     LPRSCNGKALTHTPRRLTSPNPVRSTPPDKCISFVLQVTI"
     CDS             16677..18686
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     352.8; E-value: 3.1e-107)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2823"
                     /transl_table=11
                     /translation="MSASLFTPLDLGFTQLKNRFLMGSMHTGLEEHPDGPARLAAFYAE
                     RARAGVALIVTGGIAPAVEGVVSAGASVLNAPSQLAPHRLVTDAVHRAGGKIAMQILHA
                     GRYSFQPRLVAPSAIQAPVNPFCPRQLSHTDILRLIADYARCAALARQAGYDGVEIMGS
                     EGYLINQFLVEHTNQRNDEWGGDEVRRQRFALAILRAVRAATGPAFIIIFRLSMLDLVE
                     QGSTLDHTIRLAQALEQQGATLLNTGIGWHEARIPTIATSVPRAAFAWVTQILRPHVNI
                     PLIATNRINHPAVAQALLDEGCADMVSMARPFLADAEFVLKASEGRSDEINTCIGCNQA
                     CLDRVFVGELTSCLVNPRACHETVLVSRPARQRKNLAVVGAGPAGLAFAVNAAARGHAV
                     TLFDAHAEIGGQFNIARQIPGKEEFSETLRYFRRQLALHGITQRLNHRVKPEDVIGFDE
                     VVLATGIVPRTPDIPGIGHPSVLSYLDVIGDKKPLGQRVAIIGAGGVGFDTAEYLAVSG
                     PSPSLDISRFCQEWGIDRSLKQPGGLLPAQPPRHARQIWLLQRKEGKPGAGLAKTTGWI
                     HRASLQKHGVEMWGGVRYQRIDDDGLHIVRNGEPQLLAVDNVVICAGQDTQRELEKDLL
                     AFGLPLHIIGGADVAAELDARRAIAQGTRLGLAI"
     PFAM_domain     16686..17666
                     /aSDomain="Oxidored_FMN"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00724.22"
                     /description="NADH:flavin oxidoreductase / NADH oxidase
                     family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2823_0156"
                     /evalue="5.40E-83"
                     /label="ctg1_2823"
                     /locus_tag="ctg1_2823"
                     /protein_end="330"
                     /protein_start="3"
                     /score="279.2"
                     /tool="antismash"
                     /translation="SLFTPLDLGFTQLKNRFLMGSMHTGLEEHPDGPARLAAFYAERAR
                     AGVALIVTGGIAPAVEGVVSAGASVLNAPSQLAPHRLVTDAVHRAGGKIAMQILHAGRY
                     SFQPRLVAPSAIQAPVNPFCPRQLSHTDILRLIADYARCAALARQAGYDGVEIMGSEGY
                     LINQFLVEHTNQRNDEWGGDEVRRQRFALAILRAVRAATGPAFIIIFRLSMLDLVEQGS
                     TLDHTIRLAQALEQQGATLLNTGIGWHEARIPTIATSVPRAAFAWVTQILRPHVNIPLI
                     ATNRINHPAVAQALLDEGCADMVSMARPFLADAEFVLKASEGRSDE"
     PFAM_domain     17799..18587
                     /aSDomain="Pyr_redox_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07992.16"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2823_0157"
                     /evalue="1.20E-19"
                     /label="ctg1_2823"
                     /locus_tag="ctg1_2823"
                     /protein_end="637"
                     /protein_start="374"
                     /score="70.8"
                     /tool="antismash"
                     /translation="NLAVVGAGPAGLAFAVNAAARGHAVTLFDAHAEIGGQFNIARQIP
                     GKEEFSETLRYFRRQLALHGITQRLNHRVKPEDVIGFDEVVLATGIVPRTPDIPGIGHP
                     SVLSYLDVIGDKKPLGQRVAIIGAGGVGFDTAEYLAVSGPSPSLDISRFCQEWGIDRSL
                     KQPGGLLPAQPPRHARQIWLLQRKEGKPGAGLAKTTGWIHRASLQKHGVEMWGGVRYQR
                     IDDDGLHIVRNGEPQLLAVDNVVICAGQDTQRELEKDLLAF"
     CDS             complement(18756..19883)
                     /locus_tag="ctg1_2824"
                     /transl_table=11
                     /translation="MSQLELSNRMLTLHRFPQMREESPLQAWDAADEYLLNQLGDAPVN
                     GPTLIFNDTFGALACALAGEDVWSISDSWLNQQATRQNLALNQLDEGDVRLLDSLAPLP
                     AAPARVLIKVPKTLALLEHQLRALRAVVTPETQIIGAGKAKEIHTSTLQLFEKVLGPTT
                     TSLARKKARLIYASFSKPELQHSEVITRWPLDGTPWQIHNHANVFARGSLDIGARFFMQ
                     HLPENIDGEIIDLGCGNGVIGLIALQQNPLAQIHFLDESYMAVASSRLNVGLNCPDDLA
                     RCEFRVNNALAGYPSDRLHAVLCNPPFHQQNAVTDHIAWQMFRDARRCLQYGGELRIVG
                     NRHLDYYHKMKKLFGNCTTVATQQKFVVLRSVKMP"
     PFAM_domain     complement(18774..19289)
                     /aSDomain="MTS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05175.16"
                     /description="Methyltransferase small domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2824_0158"
                     /evalue="1.90E-53"
                     /label="ctg1_2824"
                     /locus_tag="ctg1_2824"
                     /protein_end="370"
                     /protein_start="198"
                     /score="180.7"
                     /tool="antismash"
                     /translation="WQIHNHANVFARGSLDIGARFFMQHLPENIDGEIIDLGCGNGVIG
                     LIALQQNPLAQIHFLDESYMAVASSRLNVGLNCPDDLARCEFRVNNALAGYPSDRLHAV
                     LCNPPFHQQNAVTDHIAWQMFRDARRCLQYGGELRIVGNRHLDYYHKMKKLFGNCTTVA
                     TQQKFVVLR"
ORIGIN
        1 tttaccgtct gccgggcgac agaatacgcg ttgagaatgg ccccgcatcc tttgaatgct
       61 atgccacaga aattgcggta catggcaaag taataggaaa aacagaattt acggggtgag
      121 gatgctgagt agcgctgcgg atgggatgga aatggccgta aaacgggcct tgccggcagc
      181 gcaaaatttg cctcttagaa aatccccgca tcatgaatat cgtgcaaatt gatggccccg
      241 gttacccgtc cttgctcatc aaccaccggg gcggcggaaa ttttctgctc atggaacatg
      301 gccagcgctt cggtcgccag ctgaccggcg ttcagggttt tactgccaac cgtcatcaca
      361 cgcgaaatac cggcctggat attctcgccc ttgtgcagcc agcgccgcag atcgccgtcg
      421 gtaaataccc cgatcagtac gcctgcatcg tcggtcaccg ccactaaacc cagcccggta
      481 cgggtcagtt cggccagagc gtcaccgacg gtgacatcac gcgtgatgcg cggtagtttc
      541 tcccctttgc gcataatatc ccccacgcag cacagcaggc gggtgcccag gctgccgccg
      601 gggtgcgtac gggcataatc atgctcgctg aagttgcgac tgcgcattaa ggcaatagcc
      661 agcgcatcac ccatgatcaa ggtatttacc gcagatgagg ttggagcaag ccctaacgga
      721 caggcttcgc gatcggtatg gatgttgata acctggtcgg cggccattgc caaaggcgag
      781 gtgggtttgc cggtaaaagc aataatgccc accggtaagc gcttgagcat gggaaccatg
      841 cgaataaatt cggcggcaaa accagagtaa gagataagta tgaccacgtc cccggcggca
      901 atcatgccca gatcgccgtg cagcgcttca gcagggtgga cataaaaagc cggggtgccg
      961 gtactggcca acgtcgcggc gatttttttg ccgatatgcc cggatttgcc aatcccactg
     1021 acgatcgctt ttcccctgca tgcccgcatc atttcacacg cctgcacaaa atgatcgtcc
     1081 agcctcgcag ccaggttcat cgcgccgctc agttccgtcg caatggtttc ccgtgcggcc
     1141 tgcaataatt tctcgcgcat agtttcagtc ctctcctgca gtgatgacgc tgatattcat
     1201 ccctgacagc tgtttaacga tatcgggtga aatcgcgttg tcggtaatca gcacgtcaac
     1261 agcatccagg ctgcacacca cattcgggct tttacgtcca aacttggaag aatcgaccag
     1321 cagaacaatt tttttggcgg cgcggcacat ggcctggctg acggaaaaaa cttcattaaa
     1381 cgtcgtgacg ccagcggtca gatccacgcc atcagcgcca ataaacaggg tatcgaagtt
     1441 gaaatggctg aatgccgact ccgccacgct gccatgaaaa gaggctgaat ttctgcgata
     1501 agtgcccccg ggcatcagga cgacccgatc gctatcgtgt tccaccagct gattaacgat
     1561 ggtcagactg ttggtcatca cggtgatatt gttgaagcgg gccagatagg gcaccatttg
     1621 cagcaccgtg ctgccagcgt caaaaatcag tgagtcgcct tcgttaatca gttcggcggc
     1681 ccgacgggca atatgcttct ttttttccgt attgatcagc gtttttctgt caagcggctg
     1741 gtctccctcc tcacgattaa gcatcactcc gccataagtg cgaatcaccg ccccttcctg
     1801 ttgaagatgg gtcagatcct tacggatcgt cgttccggtg gtattgaagc gcacgatcag
     1861 ttgatctacc gtggtgcgcc cgttgcgctg caaaaattcg aggatctgcg cctgacgttg
     1921 tatcggtttc atcgggatat ccttttcggt ggctaaagta ttccccccat cccaaccgcc
     1981 tcaacgcgtg atgcaaaagg aattatcttt caaaacgaaa gtaattatcc tttatgtgaa
     2041 atggccagag caagcgcttg ttgagttgct gcgcttttag ggaacaatat ttggggctgg
     2101 atctcattta agcacaagcc attcaacttt ggctcattcg ccgggcgtgc aaaaatcgtt
     2161 acgcccttca tcacaaaatt gtccgtcacg cgctgctcct catccaggct tagcgctaaa
     2221 accacccgag gtttaaagcg cccgccagag cgtccaatca ccacctggcc agtctggccc
     2281 agcgccgcca gcgcgcggtt gaagttctgg atctgaaacc atcccagtaa gatttgacct
     2341 acccaggccg tcacggccag caatatcagc gtattcgttg catccatatt tcacctctga
     2401 ataaagccct ggcagcctga gctgccagct gccattaaaa catcacctgc ccaccggtga
     2461 cattaatcga ctggcctgtg caataggccg ccttgtcact cgcgtaaaac agcaggacat
     2521 tgagtacatc ctggtaatca catccccgtt taagcggcac cttgtcgacg taatagggtt
     2581 caacctcttc aggcgtgatg cccagttttt ccgcatattg tggtaacaga gactggaaca
     2641 tcggcgactt aagcagatta cccaacatca gagaatgtac ggtaatacca tattcagcca
     2701 gatccagcgc cagcgactgc gtcaggccca caccaccaaa tttagccgcg ctgtagccag
     2761 agttatgctt gctgccaacc ttgccggatt tagaattgat ctgaatgatc cgccccttga
     2821 taccgtccct gatcatcaac ttagaaaact cacgcgaaca gaggaaatag cccaccagat
     2881 taacctgcag cgacaggtca aaatccgtca acctgaactg ggtaataggg gcagctttcg
     2941 ccacgccagc actgtaaacc agcaggtctg cacgaccaaa ggtctcgtct actgcacgcg
     3001 ccagggcctc cacgctggct tcatcggtgg catccacctt aaagccgtat gcccggcccg
     3061 caccgtaacg gctgttaatg gtatctgcca gccggtttgc attactttca ttaaggtccg
     3121 ccaccgcaac gtgatagcca gcctgcgcca gtccctcaca gagaaaagcg cctaacgtct
     3181 gaccaccacc gatgactaca gcaacctgtt ccatctcatc tctcctgatt attcactgac
     3241 aacacgaaat ttttggccgg gttcaatcac caacgggggc tgtccggtta cgtgaaccga
     3301 accgggaaac tcggcgtgat ttgccccatc aaaacgaacg gtgatatgac ccaggtcgcg
     3361 caagttttcc cttgcaacct cgccgactgc ggtcaccgga taatgctgtt cgccaatggt
     3421 caacatcgag ccagcgccta ataagccacc ttgattaatg tcgttacggt ggataaagca
     3481 atattcagcg atatcttctg gtgcgccttc accaaaggtg atgagaaagt catctgccaa
     3541 tgattcgcag gccgatgtac cgacagcaac aaaagtagat tcatacacaa tcgtcataat
     3601 ctcttcccca gttaatggta gataaagctg gatgccgccc aggccagaag aacggtgggc
     3661 gccccggtaa tgaaacgtcc gaccagcacg gcaggtacgc caacacgtac ggtctcctgg
     3721 cgcgcattag ccagcgacaa cccgaccgga ataaagtcac atgccgcctg ggcgttaatc
     3781 gcgaataagg caggcagcgc cagatgtgga ggtatcgtgc cctggcctat ctgcacccca
     3841 accagcacgc caataacctg agcaataacc gcgcccggcc ccagaaacgg tgacagcagc
     3901 gggaaagaac aaatcagcgc cagcgtgact aatcctaccg ggctgtttgc cagcggcgtc
     3961 aaaccgtgtg cgataaagtc accgagtccg gaagccatga tgatgccgat taaagctgaa
     4021 acgaatgcca taaaaggcaa tatggttttc agcacggtat cgatggtttc gcgtcctgac
     4081 tggaacaaaa tggcgacggc ggagcccatt cccatcccga ctttggccag caggccatcg
     4141 ctttgctcgg tgatcttttt actggtgtcg taatcacgcc ccgtgccttt gccggcattg
     4201 acggcaacgt ccgccactgc gacttctggc ggcgcagcct ctgcgtcatt ggcgacacgt
     4261 atatcggcca ccctgacgcc tgacacatag atatcttcgg tgatgaattg cgccagcggg
     4321 cctgatttcc cggtggcatg gatgttaata gttggaatac gtcgcttagg gtaaagcccg
     4381 catcgcagag tcccgccaca gtcaataacg gctacgccaa tctcttcagc cggcggctcg
     4441 ccctgtttga atccgtctac cgcctcccaa ccggtaagcg ctaccaggtg gtcaacaatc
     4501 gctggtttgg tgccggcagt gatataaacg attttttttc ccgcagtgac gttaatagag
     4561 agagggccgc cccaaccact ttccccttta cgtatctcaa ttgtattggc catttcctgc
     4621 tccggttctt atagatgcac tgatttatca agtttgatgc ccatcttttt ctcaaaaaca
     4681 gaggtcgtca gatcggtcac ccagccacgg aaaaagttag tgataagtcc caccagcagg
     4741 tagctcacgg caagaggtcc gagcggtacc ccaagcgtag tgagaccgtt agcgatgcca
     4801 agatagacaa acagctcccc cggattgata tgcggaaaca ggccattcat tgaatgacag
     4861 ctgtacgagg ccgcagcgta atagcttggc ttgtatttct ccggcagaaa cttgcccagg
     4921 ctgtgggtca tgggattgca aaacacaaag gtgccgataa atggcagcac cagatagcga
     4981 gtaacagggt taccggcaca tttctgggcc agcttttcaa tgcggcgctg accgacaaat
     5041 acaatcagcg cgttcatgat aactaacaga ctaataagga gagggagtat gccggtcacc
     5101 atcccgacaa aaacctcgcc tcctttctgg aaaagaccga taaaccattc ggccccatgt
     5161 gtgatagctt caatcattgt tgatctcctg gcgtaaagaa ctgtcgtttt ctcttaaggc
     5221 aggaacaaat tagatcgaaa atgaagtaaa taaagctacc aaagtcacaa aatgagtata
     5281 aaaactttta atctgaaaga agaaatgaaa gatattacct ttcatttcac atactaatgc
     5341 ctttacaata gcatgcatga gcatagttca ggctgcgtct gagccgaaga ggtgactaaa
     5401 atgaacggta aaatatgatt tttatcagca aggtaaagca gaaaaatagt acagaaggaa
     5461 agtgcagcag cggggctgtg ccggctgctt aaatatgctg caggcataac gtgaaatgaa
     5521 atgttttaaa ggaaaagctg aaagtctggt gcaggctgct ggcggatacc ttatgcactc
     5581 cggtccctgt ttgccaccgg agccccttta aaccccggcc cggtcgggtt aaacactggt
     5641 ctgaacaaga gcaagctgat aacacagggg caaatacccc agagggtaaa tatgacgaac
     5701 atcaccgtca taaacggcag ttattccgtc cttaacgtcg gtaaataacg ttcagctgct
     5761 gacaaaatta tttcccgtac gatccagtca acagcggaac ccggagggat cccgtcatga
     5821 tcatcctgca aaactccttt ctgtgtctga agcacgccgc ccttaactaa caggtagcac
     5881 cctccgcaac gctttttggg tcagaattga gcctgtcaaa attcgtaatc tactgtttct
     5941 tttcatcatt tttgattaag gattcaataa actttttttg cttctcattg agcttaagct
     6001 tttttaattg ttcggccagc ttgttgggat cgtcttgaac aggctgttgc aacgccttct
     6061 ttatatcgtt cgctacccgg atcaaagaga caaagatcaa cgccaaaagt aatacacaaa
     6121 agatgaagac ggctatccac gtcgttctta tactaatttt cattttccat ccccataacc
     6181 ataagcatca ttaagacaaa tctcataacg aaatggttca aagcaggaat gataacagtc
     6241 agaagcttta ttcttagcgc ataatctcaa tttattccgt ttgatatgct acaaaaactc
     6301 tttttcacgg catataaaat tattatctcc cgaagcagtt ttacgatccc tttacattca
     6361 gagagtttgc gcagccgggt aaaaatccga tcgtcatcct gaggaaatgg gcgccagggg
     6421 aaggtcaccc tagtcaatag cggggacaga agcgaaatgt gtaaacgcct ttcagaagcg
     6481 atttgcaggg atgccaacca gcgtccaggc gttatggcgg tcggagagca ggcgctgatg
     6541 gtagtctgac aggcgttccg gggtcagccc ctggataacg tactcatcgg gctgaggtac
     6601 cgactgttgc gcagccagcc agcgctgccg gcactcctgc tggaaatcag acgctgccag
     6661 cctttgttgc gccagcaatg ccgccccctt ttcacgcact gtttccatgc tgagagcggc
     6721 cagttcatcg tccattcctg gcaagaaacg gtcgatatgc gccgaaagct cgccggtgct
     6781 cagatgggga gattgcaggg caaacagcag ccccgaccgc cccgccgcct ggtaaaaacg
     6841 gcagctgacc acataaccaa tattctgctc cacgcgcaga cgttggaaaa atgcaggttg
     6901 atagatcagc gccagcagct gccaggccgc caggcactgt gtgctgtttt ccaccagcgg
     6961 gcagaagcgt aacaaggtcg catcgtggct gatggtcgcc acctgatatt caggctgcgg
     7021 tgctaacggc tctggctgca tccggcccgg cggattgatg gtgccgggaa atgcgctaag
     7081 cagctgcgac aacgactggc ggagcgcatc gtccccgcca tcgaggaccg cctgccacgc
     7141 caggcgcggc agccgccgcc ctgccggttg gtaaaccgat gaacgcaaca gcgcgggcag
     7201 tgcatcgatc agggcgcgta ccgcaatccc ctcacgctgc gcctgctgct ggcgttggta
     7261 ttgccgctcg cccagcgcga tcatcacagg ggatatctca cacagctggc ggatcagcgt
     7321 tgccagcgtg cgcaccatta acgccgggct gccgcacagc tggatcagcc aatgaccctg
     7381 ctggcagctg acgctcagat cgccgccctt atgggcacag tcggctgcca gcgctctcag
     7441 gcgcgattgc aggatgactc cccagggcgc atgaagttca tccagcgggc ttagcaacag
     7501 cgccgcacgg cccttacccg cccgctgatg gttcagcgcg acctgcccgg cgggtaatgc
     7561 tgcctgagcg tcaggctggc tttcgcagaa aaaagtcagc gcttcagcgg ggattaacgc
     7621 ggttaccggc gcacgcgttt gcgcagcgca gcgcagcctg aagccctgaa cgctgcactg
     7681 ctgcgccagc gactgcgcgc cgatccacaa gcgggctaaa cgcgctactg acagccgcgc
     7741 acagaaccct ggccagtcgt cttgctgtac ttgcggcgga gcaaaaccaa cggcgtgttc
     7801 gcgtaactga tccatcggcg aaagcctggc aaactgaaag tcagcgagcc gcatatagtg
     7861 ctggcgctgc cgcgccgtca gtgccgtcag tcgttgcagc cagtgatgca cccaaccttc
     7921 cacctctgcg gcctgctgct catcaatcag cgccagttca acgctgacca gtgtttgcat
     7981 cgcgctgtga taaggcacca gcagccgcgc gccatcgcag agatggtgcg cacgcagcgt
     8041 tgccatcagg ccacctgcgg cctcatccag taagagctgg cgcagcaaag tcagctcgtt
     8101 actgcgcggc ctgtccagca ggaaagagag acgcaaacgc ggcgatcccg ccagttgcaa
     8161 agccatatca ggctgcgatg aataatgcag taacggaagc gctggcggtg gcacaccaac
     8221 agcagaaaac gcactgccgt actgtcgggc cagctgccat aacgcttcgg gcgactgcgg
     8281 tccctgcaac cacagcgtga tattcgccgc gtgataatag cgttgatgaa actgctgtaa
     8341 cgccagccgc agtgccggcc agtccccggt aaaactcgcg gcgttaccga tatgaaaacg
     8401 ctgccacgga tgtgcggcaa atgccatgct ctgcgcggca ttgcacaacg tatcctgctg
     8461 cccggccagc aggcggcact cggcgtcaat ggtagccact tcctggcgga tggcattttc
     8521 tgccaacagc ggagccagca gcatatcgct caaacgagcc agccccggag ccagcagccc
     8581 ggcatcgcac tcgaaaaaaa aggccgtgct gctgccctgg gtggtggcat tcagccgccc
     8641 tcccctggcc ggtaaccagg ccatcagccg ctcgtcatcc gcataagcgc aactgccggc
     8701 aaacagcaaa tgttccaaca gatgagccag ccccggccag ctgtccggtt cataatggct
     8761 accggtatcc acctggaaaa gcgctgcagc ctgtactgcc tgcgcatcgc taatcaacac
     8821 cacgcgcaaa ccgttgtcga gccgtcgtcg ctgtggctgc atccgtcagc ccttgaagat
     8881 cagctgggcg ttaacccgct gggagtttgc gcgattacgg aaccgtagct ggttcacctg
     8941 aatgtggctg cagttggcct gttcacgcgc ggcaaggatg gtgccgtgat gttctgactt
     9001 gctgcatacc gggtcggcgt tatcagcgtt gccggtcagc ataaacgcct ggcagcggca
     9061 gccgccgaag tctttctctt tttcatcaca ggatcgacat ggctccggca tccagtcaaa
     9121 gccgcgataa cggttaaagc caaacgagtt aaaccagata tcctgcaggc tgtgctccag
     9181 caccgacggg aaaggtatcg gtagctggcg ggcgctgtga cagggcagcg ccatgccttc
     9241 cggcgtgacg ctgaggaaga tcgcgcccca gccgcccatg cagcccttag gccgctcttc
     9301 ataatagtcc ggggtgacga acagcagatt ggccagatta ccgctggcgg ccatcttctc
     9361 gcggtagtgg tgcaccaccg cctcggcgcg tgccagctgg tcgcgggtag gcagcagtcc
     9421 ctcgcggttg agctgcgccc agccgtaaaa ctggcaggtt gccagctcga catcatcggc
     9481 ttccagttcg atgcacagct cgataatgcg gtcaagctgg tcgatattgt ggcgatgcag
     9541 cacaaaattc agcaccattg gatagccgtg cgctttaacc gcacgcgcca tctccagctt
     9601 ttgttgaaat gcctttgtcg atccggccag cgccgcattc agggtttcat cgctggcctg
     9661 gaagctgatc tgaatatgat ccagtcccgc ttcggcgaag gcgtcgatct tcttctgcgt
     9721 caggccgatc ccggaggtaa tcaggttggt atagaaaccg agatcgcgcg cgctgcggat
     9781 cagctcgggc agatcgttac gcaccagcgg ttcgccaccc gaaaagccaa tctgtaccgc
     9841 gcccatcgcc cgcgcctgct taaagacgtc gatccactgg gcagtcgtca gctctttttc
     9901 ctgccgtgca aagtcaagcg ggttggagca atacgggcat tgtaacgggc agcggtaggt
     9961 cagctccgcc agtagccaga gcggcggttt gatcggtgat tcagctgggt tcacggaaaa
    10021 ttatccactt ctgttcacgc gcggcggcaa agaaatcggt gacgtcatca tcaacgccac
    10081 ccgcgtccgg gaaccgcaca ttcagcgtac gggcgatatc agccagcgag cgttgaccat
    10141 ccaccagttc gaggatcatc gttgcgctgt cgttgagttt agccatccct tcgggataga
    10201 ggatgacatg gcaattctgc atctcttccc attgcagacg atatccacgg cggaatatgg
    10261 gaatgcgttg gtcacatttc acagcagatt tcctttatgc cagacgggtt gatcggtcac
    10321 ggtgtgataa ggcgcacggt taagtgtata cgccatggtc atggcatcca gcatgctcca
    10381 caaaatatcc agcttaaatt gcaggatctc cagcatacgc tgctgttttt caacgctgtt
    10441 gcagtactca agcgccagct gtaaaccatg ttcaacatcg cgccgggcct ggcccaggcg
    10501 accacggaaa tagccgtagc cctcttcctc gatccacggg tagtgctgcg gccagctgtt
    10561 gagacgcgac tgatggattt caggggcata cagttcagtc agtgagctac aggcggcttc
    10621 ctgccagacg gcacggcggg caaaggaaac gtaggcatca acggcaaagc gcacgccggg
    10681 cagcacccgc tgctctgact gcagcacatc acgatccagg ccaacggctt caccaagccg
    10741 cagccaggct tcgataccgc cctcgctgtc gccctggcca tcatggtcga gaatacgctg
    10801 tacccattta cgccgggtta acgcatcccg gcagttcgcc ataatcgcgg cgtctttcaa
    10861 aggaatacgg gtctggtaat aatagcggtt cgccacccag ccctggatct gctcacgcgt
    10921 agcctcgccg ttatgcatag cgatatggta cgggtgatga atatggtagt aagcgccgcg
    10981 agcgcgcagc gcctgttcaa actgttgtgg agtcatcaat gccggttggg tcatagttct
    11041 atgctcatgc cgtcgtagct gacctcgatg ccgcgtgcgc tcaacgccag acgctcggcg
    11101 gaggattcat caaggatcgg attagtatta ttaatatgga tcaggatctt gcgcggtgcg
    11161 ggcagatcgc ccagtagcgc catcagcccg cgatcttcat ccagcgccag gtggcccata
    11221 tcgcggccgg tgttgcgccc aacgccggta tttgccagct cgttgtcctg ccacagcgta
    11281 ccgtcaacca gcaggcagtc ggcctgcgac atcaaatcca acagctgcgc atctggttcg
    11341 cccaaaccgg gggcatacag cagtttgctg ccgctggcgg tattttcgat catcagcgcg
    11401 atattgtgtc cgggaagcgg acgcccgcga tacggtgagt aaggtggggc gttgctgagg
    11461 atgggaatag cagtaaaccg caacgccgga cacaccgcga cggaaaaagg ctgcgcgagc
    11521 tgaatagcat gatgcaccag tccaccgttc cagtgttgca gcatggtgaa gatcggaaaa
    11581 ccactggtca gatccgcgtg cacctctgct gtgcaccaca catgatgtgg gcaaccttct
    11641 cgcagattca gcaagccggt gcagtgatcg atctgactgt cggtaagaat gatggagcca
    11701 attcccgaac cgcgcagctt accctgtgga tgaagttcgg ggttggcagc aatctgatga
    11761 cagatatcgg gcgaggcgtt gcaaagcacc cagtcgctgc cgttatcgct gaccgcgatg
    11821 gaagactggg tgcgggccgt ggcgcggatg ctaccgttac gcacgccctg gcaattaggg
    11881 caatagcagt tccattgcgg aaaaccgccg ccggccgcag atccgagaac tttgattttc
    11941 atgggttaac cgggaaaggg aatgaaaaaa tgcctgggct taaccacagg catcaccgtt
    12001 ttagccagcg ttattcacat tgtgataagg cgaggggtta acgattagat atatataacg
    12061 tgacttccag ccccagacgc atatcgataa acgttggttt agtccactgc attatcattt
    12121 cctcaggtgt aaaaaaagct caagtcttca atgttgacca aaatagctac attatcgaag
    12181 ttaataacgt agcgggacag attgcactga tgataaatcg atatcaaccc tgtactttga
    12241 gcagattatg ctaaccggac cacttttttt aaaattaacc aattaatttc cccacgtttt
    12301 tcgcaggatc cttagccagt tcgcgcggca cagctttgcc aacagcggct cgctataacc
    12361 cgcaccgcgc agtacggcca gcagccgggg caatccgctg acatcgcgga tatcatccgc
    12421 caggtggacc ccgtcgaagt ctgaaccaaa cgccacgcgg tcttccccca gcttttccag
    12481 caggtaatca aggtgccgga ccatcacgct tagcggcata tcgccgccac gcttgccatc
    12541 gctgcgcaga aatgcagtac caaagttcag ccccaccagc ccgtcgctgt aggcgatcgc
    12601 tgccagctga tcgtctgtca ggttgcgggg ttgcgggcac agggtatgca cgtttgaatg
    12661 gcttgctacc agcggagcat tactcagtct ggcggtatcc cagaacgcct tttcattcat
    12721 atgtgaaaca tcgaccatca gccgacgctg attacacagg cggataagct gttttcctgc
    12781 tgcggtcaac ccctccccgc tatctggcga accggggaaa ctgccgctga cgccaaaacc
    12841 aaaacggttg ggaaggttcc agaacggccc gatgctgcgc agtccggcat ccacccagcg
    12901 atcgagctgg ctcaggtcgc catccagcgc tgccgcccct tcaatatgca tcaccatcgc
    12961 cagtacgccg ccggccatgc actgctcaat ttcgctggcg ctgcggcaga tcttcgcccg
    13021 cccgcccgac tgcgatgcaa gctgttgcag gatggcaatc tggcttgcag tgatcgccag
    13081 cgcatcgtgg cgcaacgctt cctgctgcgc gtcccgtccg tggaacgttg ccacgtaatc
    13141 tgagggcggc acgaatacgg caaacagccc accggcaaaa ccgccctgcc gcatacggct
    13201 aaaatcgaga tgaccactaa gacgccggtt gaaaaaggcc tcggcagggt tttccgggtg
    13261 gttcagccac agatgcagca gcaggtcgtt atggccatcg aagacggggt ttaacgggga
    13321 ggaatcggtc atcaggttgc catcttctca atcgtaaagc cttaataata tacccccaat
    13381 caggggccgg gcagcaaaaa ggccactctg ctgccgtggc cttatctctt gctgcacgct
    13441 ttttacgcca gcttaaccgg ccagtgagtg agctggatac cccgctgttg cgcctcatcg
    13501 ccaaattctt gcagcaccgc agtcacatcc gggtcaagat attctgcatt gtcgtggtca
    13561 acgatcacca cgctgttttc cgggatctgc gccagcaggc ctttcagacg aggattatgc
    13621 ataaagttca ggttttgctg gaagcgcagt acgtaatgat cgtcatattg cgtcagcatc
    13681 atcgcattac gctggctgcg ccaggtactg aacaggactt gcgtgataag gccaatcgca
    13741 atccccgcca gcataccgaa gatcaaaatg ccgccaacgg tggcgaggaa aggcaccgac
    13801 tgctgcgccc cctgacgaat ttgcgacacg aacagccgcg gagatgccag cttgtagccg
    13861 gtatataaca gtaccgcagc aaggctggcg agcgggatgg cattcagtaa gccactgaac
    13921 cacaggccgc aaatcagcaa taacaagccg tggatcaaaa tggacagctt actctgcgcc
    13981 ccggcgccca cgttcaccga actgcgcacg atcaccgcag tgatcggcag accgccgagg
    14041 aaaccgcaca gcgcattacc cagcccctgg gcgcgtagct ctttgtccgg cgagggtgcc
    14101 ggatgctgca gacgtatttt ctgcaacgcc tcctggctga gcagggtttc caggctggcg
    14161 accagggcca gcgtgacggc caccatgtac accgccgggt tttgccaggc catccagtca
    14221 gggcgctgca actcaccggc cagcgatgtg atgctgtcaa atgcaggcaa tgaaatgcgc
    14281 ggaaggttgc tcgctaattc aggaaacaga cgcccgccga gaacggtggc cacgcagcca
    14341 agcagcaccg ccatcagcgg gcctggcatc cagcccagcc agcgattttt tttcaccgcc
    14401 gacgtcgtcc acagccagag aaccaataac ccactgagcg cgaccgccat cgcgggtaaa
    14461 gagatattca gtgcactgcc ggtcagccac gaggccaaat cgttttcacc cgctgcgcca
    14521 agagcaaccg gaatttgctg gataatcaga aggatgccaa tagccgccag cattcctttg
    14581 atcacgctgc ccggcacaag gctgataaat cgccccgcgc gtaccacgcc cagcgagaat
    14641 tgcagtacgc cggccacgat cagcgccagc agcagtgcag agaaggaacc gagcgtttca
    14701 atcgcgccgg tgacaatagt gaccagccct gccgccgggc cactgacagc gaacctggat
    14761 gggctgaaag tggtgaccac caggcctcca accacgccgg tcagcagccc gacaaacggt
    14821 ggcagaccgc tggcctgggc aatccccagg cacagcggca aggcaaccag aaacaccact
    14881 aatcccgcgg gaatgtcccg gcgcaaggtt tgtagattca cgtgcaaccc ccctctgact
    14941 gttgctgaac cagctctttc agatgtccgc tgtgcaggtc gtaaacgcaa ccaaatacgt
    15001 caagatcggc tcctttacgc cacgcgttaa ccaccggcac ggtttgcacc agctggctga
    15061 actgcgccag tacattggct tcgacaaggc gattgagacg agcaacatcg tcctcttgcg
    15121 cattgggcgc agcgagctgg acggacagcg cttcgcgcaa cagggtgata cgccttgcca
    15181 gcgctgaatt ctcatcattt aacggcagat ccggcagcgt cagcgccgcc tgcacgccgc
    15241 cgcagccata gtgtccacaa aggacaatgc gcgaaacctg caaatattcg atggcatatt
    15301 gcaatacgct cataaaatta tcgtcattgc tgacgaccat attggcgata ttacgatgca
    15361 caaacagctc gcccgggtgc gaattagtca gaacttctgc cggaacccgg ctgtcggaac
    15421 agccaatcca taatgaatgt ggctgctggc cttctgcatt ttgctgaaaa tattgtggat
    15481 gacgctgctg tcgctgtaat gcccaactgc ggtttttagc taacaggggt ttgagtgtcc
    15541 tcaagatata atctctcttc cagaaacaga tattcaaata actgagaaat aagttttaac
    15601 acttagatca ataaaatgcg attaggaata gtcctaagtt tgatgggtat atttttttta
    15661 aattaattat gccgtctttt tgcatgcgtt cagtccagtc tgacattgag taaactaaac
    15721 ttagttcggg cgcgacgcaa gcacaggcaa gatcaaattt cgctattttt catacaatta
    15781 aaaattaagc ctcggttaac attcaatcaa aaaaaatatt ttttttaaat ttacaactat
    15841 ttcataacgg ttttaaacca tggatgacca ttgaataagg agggtgaaac gatgagcata
    15901 agcgccatga aatatattag ttagttgcct gtgtaatcaa taaatgtcag ttaatctgga
    15961 gctatttaaa caaatttaca ttagataatc gggctgcaca taatatgtca acgcttagcc
    16021 cttctaatgg cagatttctt tccgtgcaac cttgtcagat cgttacctgt aaaacaaacg
    16081 agatgcactt gtccggcggc gttgacctta ccgggttggg tgacgttaaa cgcctcggcg
    16141 tgtgggtcaa tgccttgcca ttgcagctcc gcggcagcag cgcaagcgcc ctgttggcgg
    16201 gcggcatgac gcatcgctgc tgcgccagcc cctgagccat cagcaacccg atgccgcgga
    16261 cagcgccgct gatcggtttc cgttggtttt cgggtgagaa aagagatgtc atggttatcc
    16321 tttgaaagtc agttgcactc tggcgagcgg tgtcgggtca gcggcaaggc gcggggccgt
    16381 ttcgctgaac ccggcatgct ggcgataatc accgctaatg atgcagaatt gcgtgatggt
    16441 gataagtgta gatcccagta gcaataacgc tctgtagcct gttggcgaaa cggggttgca
    16501 ttggcagaac cgtgactgag atcgctaaag ttgatgttac agataacccg aagcaggttg
    16561 tccttacgcc ctgctaccaa tcagtggcat tcatcacaaa gcgctaatcc tgtctttcac
    16621 cctgctcgtt tgcccgctac agttgaactc atccgaccac ttcaggattg ccgaccatga
    16681 gcgcatcact gtttaccccg ctggacctgg gtttcaccca gcttaaaaac cgttttctga
    16741 tgggatcgat gcataccggg ctggaagagc atcctgacgg gcctgcaagg ctggcggcat
    16801 tctatgccga gcgcgcccgc gccggggtgg cgttgatcgt gaccggcggt attgcgccag
    16861 cggtggaagg cgtggtcagc gccggggcgt cagtgctgaa tgccccttca cagctggcac
    16921 cgcatcgcct ggtgaccgat gcagtgcacc gggccggggg gaaaatcgcc atgcagatcc
    16981 tgcacgccgg gcgctacagt tttcagccca ggctggtcgc cccgtccgcg atccaggcgc
    17041 cagtcaaccc gttttgcccg cgtcagctaa gccatacaga cattttgcgt ctgattgctg
    17101 attacgctcg ctgcgctgcg ctggccaggc aggcaggcta cgatggcgtg gaaataatgg
    17161 gttctgaagg ctatttaatt aaccagttcc ttgtggagca tactaatcag cgcaacgacg
    17221 aatggggcgg cgatgaagta cgccgccagc gttttgcgct ggcgatcctc agggcggtgc
    17281 gcgcagctac cgggccggcg tttatcatca tcttccgcct gtcgatgctg gacctggtgg
    17341 aacagggcag cacgctggat cacactatcc gcctggcaca agcgctggaa cagcagggcg
    17401 ccacgctgct caataccggt atcggctggc atgaagcgcg tatcccgacg attgccacct
    17461 cggtgccgcg tgctgccttt gcctgggtaa cgcaaattct caggccgcat gtcaacatcc
    17521 cgctgattgc caccaaccgc atcaatcatc ctgctgtcgc ccaggcgctg ctcgatgaag
    17581 gctgtgccga tatggtgtca atggcgcgcc cgtttctcgc cgacgccgag ttcgtgctga
    17641 aagccagcga ggggcgcagc gacgaaatta atacctgcat cggctgcaat caggcctgcc
    17701 tcgatcgcgt cttcgtcggt gaactcactt cttgcctggt caacccgcgc gcctgccacg
    17761 aaacggtact ggtcagccgc ccggcgcgcc agcggaaaaa tctggcggtg gtcggtgccg
    17821 ggccggccgg gctggcgttt gccgttaacg ccgcggcacg cggacatgcg gtcacgctgt
    17881 ttgatgcgca cgcggaaatc ggcggccagt ttaatatcgc ccggcaaatt cccggtaaag
    17941 aagaatttag cgaaacgctg cgctactttc gccgccagct ggcgcttcac ggcatcaccc
    18001 aacggctcaa ccaccgcgta aaaccagagg atgtaatcgg cttcgatgaa gtagtgctgg
    18061 caaccgggat cgtgccacgc acgccggaca ttccggggat cggtcatcct tcggtactca
    18121 gttatctgga cgtgattggc gataaaaagc cgctgggcca gcgcgtagcc attatcggtg
    18181 ccgggggcgt tggcttcgat acagctgaat acctcgccgt cagcggcccg tcacccagtc
    18241 tggatatcag ccgcttttgt caggaatggg gcatcgaccg cagcctgaag cagccggggg
    18301 ggctgctgcc cgcgcagccc ccccggcatg cacgtcagat ctggctgttg cagcgcaaag
    18361 agggcaaacc cggtgccggg ctggcgaaaa ccaccggctg gatccaccgc gccagcctgc
    18421 aaaagcatgg ggtagagatg tggggcggcg tacgctatca acgcattgac gacgatggcc
    18481 tgcatattgt ccgcaacggc gaaccgcagc tgctggcggt cgataatgtg gtgatctgcg
    18541 ccgggcagga tacgcagcgg gaactggaaa aggatctgct ggcttttggt ctgccgctcc
    18601 atatcatcgg cggggcagat gttgccgccg aacttgatgc acggcgggcc attgcccagg
    18661 gcacccggct tggtttagcg atttgactgc gtgcctgagg atggatcaac ggcgctgcct
    18721 tgttgtccgg cccctcccct cgccactccg atcgcctaag gcattttcac cgaacgcagc
    18781 accacaaact tctgctgcgt cgccacagtg gtgcagttcc caaacagctt cttcattttg
    18841 tggtagtagt cgagatgacg attaccgacg atacgcagct cgccaccgta ctgcaggcag
    18901 cggcgggcat cgcggaacat ctgccaggcg atatgatcgg tgaccgcgtt ctgctggtga
    18961 aagggcggat tgcacagcac cgcatgcagg cggtccgagg gatagccggc cagcgcattg
    19021 ttcacccgga actcgcagcg tgccagatcg tcggggcaat ttagcccgac gttcagacgg
    19081 ctggatgcga ccgccatata ggattcatca aggaagtgga tctgcgccag cggattctgt
    19141 tgcagggcaa ttaaaccaat cacgccgttg ccgcagccga gatcgatgat ttcgccgtcg
    19201 atattttccg gcagatgctg cataaagaaa cgcgcaccga tatccaggct gccgcgagca
    19261 aacacgttgg cgtgattgtg aatttgccag ggcgtaccgt ccagcggcca gcgggttatc
    19321 acctcgctgt gttgcagttc gggtttgctg aacgaggcgt agatcaggcg cgcctttttc
    19381 cgggccagcg aggtggtggt cgggccaagc actttttcaa acagctgcag ggtcgaggtg
    19441 tggatctctt tcgctttacc ggcgccgatg atttgcgttt ctggcgtgac tactgcgcgc
    19501 agcgcacgca gctgatgttc aagtagtgcg agagtttttg gcacttttat cagcacccgc
    19561 gccggcgccg cgggcagagg agccaggcta tcaagtagcc gcacgtcgcc ctcgtcgagc
    19621 tgattcagcg ccagattctg ccgggtagcc tgctggttca accaggagtc gctgatgctc
    19681 cagacgtcct cccccgccag cgcgcacgcc agcgcgccga aggtatcatt gaagatgagc
    19741 gtcgggccgt tgaccggggc atcccccagc tggttaagca ggtattcatc ggccgcatcc
    19801 cacgcctgca acgggctttc ttcgcgcatt tggggaaagc gatgcagcgt cagcatgcgg
    19861 ttgctcagtt caagttggct catgggatca ccttagtggt aaaattcccg cgttttatcc
    19921 cccaaaacgg gcgtacagta aacgtttttc ttcaccggag tcagtatgtc atcgcttatt
    19981 tacctgcaag gttaccctga atcgctgctg tctcaggtgc gcaccctgat tgaacagcag
    20041 cggctgaaaa aagttgtcag ccagcgttac cccgcgatgc acagtatcac cagcgacaaa
    20101 gcgctgtacg actacgcgct gaatttaaaa aatcaggcgc tacgcaatgc accaccgctg
    20161 aacaaagtca tctacgacag caaaattaaa gtgatgaagc acgcgttggg gctgcatacg
    20221 gcgatatcac gcgttcaggg cggcaaactc aaagctaaag ctgaaatccg cgtcgcaacc
    20281 at
//
