LOCUS       NZ_KB904599.1          14794 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KB904599.1 Streptococcus thoraltensis DSM 12221
            A3IADRAFT_scaffold_20.21, whole genome shotgun sequence.
ACCESSION   NZ_KB904599
VERSION     NZ_KB904599.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:47:09
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14794
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14794
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4305:4794](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4306..4794
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14794
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14794
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             504..1850
                     /locus_tag="ctg14_1"
                     /transl_table=11
                     /translation="MKSVIYHDFPLLPNVMTSVSDMMKLQKPKGTQDILPADSAKWQYV
                     ENFARETFKKYNYGEIRTPMFEHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEG
                     TAPVVRSYVENKLFAPEIQKPVKMYYIGSMFRYERPQAGRLREFHQIGVEAFGSSNPAT
                     DVETIAMAYQLFTELGIKDVVLHLNSLGNTSSRQAYRQALIDYLTPMRDSLSKDSQRRL
                     EENPLRVLDSKEKEDKLAVENAPSILDFLDDESQAHFDEVRAMLEALNIPYVIDTNMVR
                     GLDYYNHTIFEFITTIEKSELTICAGGRYDGLVEYFGGPETPGFGFGLGLERLLMILDK
                     QGIELPIESDMDLYIAVLGAEANSKALELVQAIRIQGFAAERDVIGRKIKAQFKSADAF
                     KAKTIMTLGGSXVEAGQVTVKNNITRQEXTVTFEEISEDFASILQRLEA"
     aSDomain        579..1796
                     /aSDomain="TIGR00442"
                     /aSTool="tigrfam"
                     /description="hisS: histidine--tRNA ligase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg14_1_0001"
                     /evalue="1.70E-154"
                     /identifier="TIGR00442"
                     /label="ctg14_1"
                     /locus_tag="ctg14_1"
                     /protein_end="431"
                     /protein_start="25"
                     /score="512.7"
                     /tool="antismash"
                     /translation="QKPKGTQDILPADSAKWQYVENFARETFKKYNYGEIRTPMFEHYE
                     VISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEIQKPVKMY
                     YIGSMFRYERPQAGRLREFHQIGVEAFGSSNPATDVETIAMAYQLFTELGIKDVVLHLN
                     SLGNTSSRQAYRQALIDYLTPMRDSLSKDSQRRLEENPLRVLDSKEKEDKLAVENAPSI
                     LDFLDDESQAHFDEVRAMLEALNIPYVIDTNMVRGLDYYNHTIFEFITTIEKSELTICA
                     GGRYDGLVEYFGGPETPGFGFGLGLERLLMILDKQGIELPIESDMDLYIAVLGAEANSK
                     ALELVQAIRIQGFAAERDVIGRKIKAQFKSADAFKAKTIMTLGGSXVEAGQVTVKNNIT
                     RQEXTVT"
     PFAM_domain     591..1505
                     /aSDomain="tRNA-synt_His"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13393.8"
                     /description="Histidyl-tRNA synthetase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_1_0001"
                     /evalue="4.00E-43"
                     /label="ctg14_1"
                     /locus_tag="ctg14_1"
                     /protein_end="334"
                     /protein_start="29"
                     /score="147.9"
                     /tool="antismash"
                     /translation="GTQDILPADSAKWQYVENFARETFKKYNYGEIRTPMFEHYEVISR
                     SVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEIQKPVKMYYIGS
                     MFRYERPQAGRLREFHQIGVEAFGSSNPATDVETIAMAYQLFTELGIKDVVLHLNSLGN
                     TSSRQAYRQALIDYLTPMRDSLSKDSQRRLEENPLRVLDSKEKEDKLAVENAPSILDFL
                     DDESQAHFDEVRAMLEALNIPYVIDTNMVRGLDYYNHTIFEFITTIEKSELTICAGGRY
                     DGLVEYFGGPETPGFGFGLGLERL"
     PFAM_domain     1560..1814
                     /aSDomain="HGTP_anticodon"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03129.22"
                     /description="Anticodon binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_1_0002"
                     /evalue="8.00E-07"
                     /label="ctg14_1"
                     /locus_tag="ctg14_1"
                     /protein_end="437"
                     /protein_start="352"
                     /score="29.2"
                     /tool="antismash"
                     /translation="LYIAVLGAEANSKALELVQAIRIQGFAAERDVIGRKIKAQFKSAD
                     AFKAKTIMTLGGSXVEAGQVTVKNNITRQEXTVTFEEISE"
     CDS             complement(2039..3343)
                     /locus_tag="ctg14_2"
                     /transl_table=11
                     /translation="MVIKGLFHLYTSIINILVINYFFSRATPQKINQLISILTLGVLVI
                     IEVLANCFLRTNLASLITVICSFLTSFYIASIYDYGRKQGLFWAILLQTIGLLFEAILG
                     FSLTLFFGDALINSATFTFIYINLLAILSIIMSFYLKHFFLFELSDTDNHHKQGAWIIC
                     LSLIPAITCALLFFQLFDSSTHYELDASTLIYSFGFMAITIISLYTYRYMMIQNTNHYN
                     TKLDNIRFQAQLHNMQNLKDSHLKVRALKHDLHNHHIVLIGLLKQEKFDEAEQLINNNL
                     AQLTETNDTFFTNELILNHLLNQKSQTAKENNICLSISCLIPSSTRLKTDIIAIIVGNL
                     LDNSISAVIRNKRTTEKKINLIINLYNEKLYIAIENGFDPQEAHSRKQRLYDGLGLRNI
                     KDIVNRYHGLYKQEINENIYKITILFPHVDSITNK"
     PFAM_domain     complement(2066..2347)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_2_0003"
                     /evalue="1.70E-16"
                     /label="ctg14_2"
                     /locus_tag="ctg14_2"
                     /protein_end="426"
                     /protein_start="332"
                     /score="60.0"
                     /tool="antismash"
                     /translation="IAIIVGNLLDNSISAVIRNKRTTEKKINLIINLYNEKLYIAIENG
                     FDPQEAHSRKQRLYDGLGLRNIKDIVNRYHGLYKQEINENIYKITILFP"
     CDS             complement(3333..4046)
                     /locus_tag="ctg14_3"
                     /transl_table=11
                     /translation="MIRIALCDDDKGVGSMVEDALDKFSNNSYFSLDVYEHPRKLYEKI
                     LTDYQLFILDIEMGDSSGIELAEYIRSKHADAIIIFLTNHRDYMEQIFHVQTFDYLLKP
                     LDRERFYQCLNRSLKILENTNHYFTFSYNHAYYKLPLKDIIFFEKDGRKVYIHTRYETY
                     TALLSTKEVLAQVSQQFIQIHNSYIFNVNYFYKFEKQMITLLQESQFINLPVSRKFKRH
                     LQDTILMKLKDSNGY"
     PFAM_domain     complement(3369..3641)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_3_0005"
                     /evalue="1.40E-13"
                     /label="ctg14_3"
                     /locus_tag="ctg14_3"
                     /protein_end="226"
                     /protein_start="135"
                     /score="51.0"
                     /tool="antismash"
                     /translation="YYKLPLKDIIFFEKDGRKVYIHTRYETYTALLSTKEVLAQVSQQF
                     IQIHNSYIFNVNYFYKFEKQMITLLQESQFINLPVSRKFKRHLQDT"
     PFAM_domain     complement(3708..4037)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_3_0004"
                     /evalue="1.20E-13"
                     /label="ctg14_3"
                     /locus_tag="ctg14_3"
                     /protein_end="113"
                     /protein_start="3"
                     /score="51.3"
                     /tool="antismash"
                     /translation="IALCDDDKGVGSMVEDALDKFSNNSYFSLDVYEHPRKLYEKILTD
                     YQLFILDIEMGDSSGIELAEYIRSKHADAIIIFLTNHRDYMEQIFHVQTFDYLLKPLDR
                     ERFYQC"
     CDS             4306..4794
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_4"
                     /sec_met_domain="ThiF (E-value: 5e-14, bitscore: 42.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 6.4e-13,
                     bitscore: 39.4, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMGYSRPRIKNIYPVYKLDKNRFRIGAQMNITREFEDPTGQLWDF
                     VKRLDGRELPLIEADLQAIYPEVTHDDIVFALELLDKEGFIEEYQDVNLVEERYMSNVN
                     YFRRYLGSYDESLTVQRKLNESSILLLGLGGGGSNILSLLAGIGPKKLTIVDYDKVQI"
     PFAM_domain     4660..4791
                     /aSDomain="ThiF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00899.23"
                     /description="ThiF family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_4_0006"
                     /evalue="2.50E-11"
                     /label="ctg14_4"
                     /locus_tag="ctg14_4"
                     /protein_end="162"
                     /protein_start="118"
                     /score="43.3"
                     /tool="antismash"
                     /translation="VQRKLNESSILLLGLGGGGSNILSLLAGIGPKKLTIVDYDKVQI"
     CDS             4803..5114
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_5"
                     /sec_met_domain="ThiF (E-value: 2.8e-19, bitscore: 60.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLYKEDDIGKLKTETALREFQKMNSSVSINAITKKITSVSDVVEL
                     LDGIDLVICAIDEPPFVAQRIVNKAIVKVGVPCVFGGSQVSRDRVYSVIPKKQDALTV"
     PFAM_domain     4806..5054
                     /aSDomain="ThiF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00899.23"
                     /description="ThiF family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_5_0007"
                     /evalue="3.40E-15"
                     /label="ctg14_5"
                     /locus_tag="ctg14_5"
                     /protein_end="84"
                     /protein_start="1"
                     /score="55.9"
                     /tool="antismash"
                     /translation="LYKEDDIGKLKTETALREFQKMNSSVSINAITKKITSVSDVVELL
                     DGIDLVICAIDEPPFVAQRIVNKAIVKVGVPCVFGGSQ"
     CDS             5310..5441
                     /locus_tag="ctg14_6"
                     /transl_table=11
                     /translation="MKQVLRSVINHGLDMKMSAQLVEKELFLSGKFLIIIIHDGKKE"
     CDS             5445..6356
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 163.3; E-value:
                     1.2e-49)"
                     /gene_kind="transport"
                     /locus_tag="ctg14_7"
                     /transl_table=11
                     /translation="MKNCLAVTNISKRYAKGKQFANKELNCEFNEGEITALIGHNGAGK
                     TTLLNQIIGITDSDKGDISYLQESFTKSPKLARSYTSMMPQMHAPLKGVSVRQAISSIG
                     GIRGIDPAALKDEVDDILEALDITKWENQKGEKLSGGLKRLTSFAMAIVGAPKIILLDE
                     PTNDVDPMRRTRLWLYLRKLASRGHILIIVTHNILEVEKYADKYYMLEQGEVKASGNVK
                     SLENMAGHLVRFTVYSQKTMESFPLDCTISDSLEVSARIETPDLPVLLTWLQDAIIAKT
                     ISNYHLSTLGLNDYYEVLSNEK"
     PFAM_domain     5511..5942
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_7_0008"
                     /evalue="7.70E-27"
                     /label="ctg14_7"
                     /locus_tag="ctg14_7"
                     /protein_end="166"
                     /protein_start="22"
                     /score="94.6"
                     /tool="antismash"
                     /translation="KELNCEFNEGEITALIGHNGAGKTTLLNQIIGITDSDKGDISYLQ
                     ESFTKSPKLARSYTSMMPQMHAPLKGVSVRQAISSIGGIRGIDPAALKDEVDDILEALD
                     ITKWENQKGEKLSGGLKRLTSFAMAIVGAPKIILLDEPTN"
     CDS             6346..7080
                     /locus_tag="ctg14_8"
                     /transl_table=11
                     /translation="MKSNYQQIRGLLIWSYVRNKSLIILCSIVQFFMSIALIYGYSLIV
                     EPRTPEAQLYLASGAVTLGMITIGCTIAAQTISSAKQDGLVTYLKTLPVKRSFILFSEL
                     FIWAIVSFLGVILSLITVFVKFQFLPQLSIGSFGLLWLILLTMLSIGFAIAYSTSPSAM
                     SLITQLILMIGLLFSPIMFPADRIPAFLLRLYSLLPFVPAGNLIRLSVYQDYPVAARDI
                     FVLLFWLLLTSSLSVWQLHRKV"
     PFAM_domain     6385..6972
                     /aSDomain="ABC2_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01061.26"
                     /description="ABC-2 type transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_8_0009"
                     /evalue="7.80E-12"
                     /label="ctg14_8"
                     /locus_tag="ctg14_8"
                     /protein_end="209"
                     /protein_start="13"
                     /score="45.2"
                     /tool="antismash"
                     /translation="WSYVRNKSLIILCSIVQFFMSIALIYGYSLIVEPRTPEAQLYLAS
                     GAVTLGMITIGCTIAAQTISSAKQDGLVTYLKTLPVKRSFILFSELFIWAIVSFLGVIL
                     SLITVFVKFQFLPQLSIGSFGLLWLILLTMLSIGFAIAYSTSPSAMSLITQLILMIGLL
                     FSPIMFPADRIPAFLLRLYSLLPFVPAGNLIRL"
     CDS             7237..8988
                     /locus_tag="ctg14_9"
                     /transl_table=11
                     /translation="MTERSMYAGRVRSEHIGTEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEEVSSDVMATAESLRNEYVIEVTGTVEARQQANDNLATGAVELKVSALSVL
                     NVAKTTPFEIKDGVEVSDDNRLKYRYLDLRRPEMLENFKLRAKVTHSIRNYLDELEFID
                     VETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRD
                     EDLRGDRQPEFTQVDLETSFLNEQEIQDIVEGMIAKVMKDTKGIEVTLPFPRMAYDDAM
                     NLYGSDKPDTRFDMLLQDLTDIVKDVDFKVFSEAPAVKAIVVKGSADKYSRKDIDKMTE
                     FAKQFGAKGLAWVKVTDGAIAGPVAKFLTNIEDDLTAALQLEENDLVLFVADKLEVAND
                     TLGALRGRIAKELDMIDNSKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPTEDSAHEL
                     EGDLANVRAVAYDIVLNGYELGGGSLRINQKDMQERMLKALGFAEEDAYEQFGFLLEAM
                     DYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKATDPMTQAPSVVADKQLEELA
                     LQLQLND"
     aSDomain        7246..8970
                     /aSDomain="TIGR00459"
                     /aSTool="tigrfam"
                     /description="aspS_bact: aspartate--tRNA ligase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg14_9_0002"
                     /evalue="2.90E-233"
                     /identifier="TIGR00459"
                     /label="ctg14_9"
                     /locus_tag="ctg14_9"
                     /protein_end="578"
                     /protein_start="3"
                     /score="773.4"
                     /tool="antismash"
                     /translation="RSMYAGRVRSEHIGTEITLKGWVGRRRDLGGLIFIDLRDREGIMQ
                     LVINPEEVSSDVMATAESLRNEYVIEVTGTVEARQQANDNLATGAVELKVSALSVLNVA
                     KTTPFEIKDGVEVSDDNRLKYRYLDLRRPEMLENFKLRAKVTHSIRNYLDELEFIDVET
                     PMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDL
                     RGDRQPEFTQVDLETSFLNEQEIQDIVEGMIAKVMKDTKGIEVTLPFPRMAYDDAMNLY
                     GSDKPDTRFDMLLQDLTDIVKDVDFKVFSEAPAVKAIVVKGSADKYSRKDIDKMTEFAK
                     QFGAKGLAWVKVTDGAIAGPVAKFLTNIEDDLTAALQLEENDLVLFVADKLEVANDTLG
                     ALRGRIAKELDMIDNSKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPTEDSAHELEGD
                     LANVRAVAYDIVLNGYELGGGSLRINQKDMQERMLKALGFAEEDAYEQFGFLLEAMDYG
                     FPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKATDPMTQAPSVVADKQLEELALQ"
     PFAM_domain     7297..7545
                     /aSDomain="tRNA_anti-codon"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01336.27"
                     /description="OB-fold nucleic acid binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_9_0010"
                     /evalue="1.20E-15"
                     /label="ctg14_9"
                     /locus_tag="ctg14_9"
                     /protein_end="103"
                     /protein_start="20"
                     /score="57.4"
                     /tool="antismash"
                     /translation="TLKGWVGRRRDLGGLIFIDLRDREGIMQLVINPEEVSSDVMATAE
                     SLRNEYVIEVTGTVEARQQANDNLATGAVELKVSALSV"
     PFAM_domain     7600..8895
                     /aSDomain="tRNA-synt_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00152.22"
                     /description="tRNA synthetases class II (D, K and N)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_9_0011"
                     /evalue="1.70E-103"
                     /label="ctg14_9"
                     /locus_tag="ctg14_9"
                     /protein_end="553"
                     /protein_start="121"
                     /score="346.1"
                     /tool="antismash"
                     /translation="DDNRLKYRYLDLRRPEMLENFKLRAKVTHSIRNYLDELEFIDVET
                     PMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDL
                     RGDRQPEFTQVDLETSFLNEQEIQDIVEGMIAKVMKDTKGIEVTLPFPRMAYDDAMNLY
                     GSDKPDTRFDMLLQDLTDIVKDVDFKVFSEAPAVKAIVVKGSADKYSRKDIDKMTEFAK
                     QFGAKGLAWVKVTDGAIAGPVAKFLTNIEDDLTAALQLEENDLVLFVADKLEVANDTLG
                     ALRGRIAKELDMIDNSKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPTEDSAHELEGD
                     LANVRAVAYDIVLNGYELGGGSLRINQKDMQERMLKALGFAEEDAYEQFGFLLEAMDYG
                     FPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKN"
     CDS             9122..9919
                     /locus_tag="ctg14_10"
                     /transl_table=11
                     /translation="MLSSIAVNFFFQPGHVYSSGATGLAQVISALTERSFGYATPISLT
                     FYAINLPLLILAWYTIGHKFTVFTFMAVSMSSLFIHLMPQVTLTTDPLINAIFGGLFMG
                     LGVGVGLRSRISSGGTDIVSLTIRKKTGRNVGSISLFVNGVIMIFAGLLFGWQYALYSM
                     ITIFVSSRVTDAIYTKQKKMQAMIVTSRPDRVVAMIHKKLHRGVTSINDAHGTFKHEDK
                     AVLLAIITREEYTEFKQLMAKADPRAFVSISENVQIIGRFNDD"
     PFAM_domain     9125..9718
                     /aSDomain="YitT_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02588.17"
                     /description="Uncharacterised 5xTM membrane BCR, YitT
                     family COG1284"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_10_0012"
                     /evalue="5.60E-57"
                     /label="ctg14_10"
                     /locus_tag="ctg14_10"
                     /protein_end="199"
                     /protein_start="1"
                     /score="192.5"
                     /tool="antismash"
                     /translation="LSSIAVNFFFQPGHVYSSGATGLAQVISALTERSFGYATPISLTF
                     YAINLPLLILAWYTIGHKFTVFTFMAVSMSSLFIHLMPQVTLTTDPLINAIFGGLFMGL
                     GVGVGLRSRISSGGTDIVSLTIRKKTGRNVGSISLFVNGVIMIFAGLLFGWQYALYSMI
                     TIFVSSRVTDAIYTKQKKMQAMIVTSRPDRVVAMI"
     PFAM_domain     9734..9901
                     /aSDomain="DUF2179"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10035.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2179)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_10_0013"
                     /evalue="1.80E-13"
                     /label="ctg14_10"
                     /locus_tag="ctg14_10"
                     /protein_end="260"
                     /protein_start="204"
                     /score="50.1"
                     /tool="antismash"
                     /translation="RGVTSINDAHGTFKHEDKAVLLAIITREEYTEFKQLMAKADPRAF
                     VSISENVQIIG"
     CDS             10212..11090
                     /locus_tag="ctg14_11"
                     /transl_table=11
                     /translation="MKFRWHLSDGIHLIWITLGVALYTFGFVNFNMANHLAEGGVAGIT
                     LILHALFGLDPALSSLLINIPLFVLGARVFGKKSLLLTIYGTVTMSIFIWIWQRVPMEL
                     GLQDDMMLVAIVAGIFAGIGSGVVFRYGATTGGTDIVGRVLEEKTGMKLGQTLLMIDVL
                     VLASSLVYIDLKHMLYTLIASFVFSQVLTVVQNGGYMVRGMLIITKESDKASAAILQEI
                     NRGVTYLQGKGAYTGRGFDILYVVLNPNEVREVKDILAELDPDAFISILNIDEVISSDF
                     KIIRKNYDKEL"
     PFAM_domain     10248..10865
                     /aSDomain="YitT_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02588.17"
                     /description="Uncharacterised 5xTM membrane BCR, YitT
                     family COG1284"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_11_0014"
                     /evalue="1.40E-55"
                     /label="ctg14_11"
                     /locus_tag="ctg14_11"
                     /protein_end="218"
                     /protein_start="12"
                     /score="188.0"
                     /tool="antismash"
                     /translation="LIWITLGVALYTFGFVNFNMANHLAEGGVAGITLILHALFGLDPA
                     LSSLLINIPLFVLGARVFGKKSLLLTIYGTVTMSIFIWIWQRVPMELGLQDDMMLVAIV
                     AGIFAGIGSGVVFRYGATTGGTDIVGRVLEEKTGMKLGQTLLMIDVLVLASSLVYIDLK
                     HMLYTLIASFVFSQVLTVVQNGGYMVRGMLIITKESDKASAAI"
     PFAM_domain     10881..11042
                     /aSDomain="DUF2179"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10035.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2179)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_11_0015"
                     /evalue="3.90E-18"
                     /label="ctg14_11"
                     /locus_tag="ctg14_11"
                     /protein_end="277"
                     /protein_start="223"
                     /score="65.1"
                     /tool="antismash"
                     /translation="RGVTYLQGKGAYTGRGFDILYVVLNPNEVREVKDILAELDPDAFI
                     SILNIDEVI"
     CDS             complement(11718..12179)
                     /locus_tag="ctg14_12"
                     /transl_table=11
                     /translation="MGGTDMSNYQKIYETSAVNTGGRSGISYVENSSFQVTISSPKEMG
                     GDGNGTNPEQLFALGYSACFNSALEVVLGLENIKAKSMITQRTQLFKADGADFKLGVEI
                     EVSVDGKSADEAKELGEKAHEVCPYSKATRGNIDVTIIGVDYDASKEAR"
     PFAM_domain     complement(11757..12044)
                     /aSDomain="OsmC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02566.21"
                     /description="OsmC-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_12_0016"
                     /evalue="1.90E-14"
                     /label="ctg14_12"
                     /locus_tag="ctg14_12"
                     /protein_end="141"
                     /protein_start="45"
                     /score="54.0"
                     /tool="antismash"
                     /translation="GDGNGTNPEQLFALGYSACFNSALEVVLGLENIKAKSMITQRTQL
                     FKADGADFKLGVEIEVSVDGKSADEAKELGEKAHEVCPYSKATRGNIDVTI"
     aSDomain        complement(11757..12146)
                     /aSDomain="TIGR03561"
                     /aSTool="tigrfam"
                     /description="organ_hyd_perox: peroxiredoxin, Ohr
                     subfamily"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg14_12_0003"
                     /evalue="3.00E-47"
                     /identifier="TIGR03561"
                     /label="ctg14_12"
                     /locus_tag="ctg14_12"
                     /protein_end="141"
                     /protein_start="11"
                     /score="158.3"
                     /tool="antismash"
                     /translation="IYETSAVNTGGRSGISYVENSSFQVTISSPKEMGGDGNGTNPEQL
                     FALGYSACFNSALEVVLGLENIKAKSMITQRTQLFKADGADFKLGVEIEVSVDGKSADE
                     AKELGEKAHEVCPYSKATRGNIDVTI"
     CDS             12625..13041
                     /locus_tag="ctg14_13"
                     /transl_table=11
                     /translation="LAQLIEGDLDKMKKIVKKEDIDLMDCYTKKMMWAMLALLFTVFPA
                     FYYLDWWGMLVYLPLAAFGIYYAHKVEKIKDNYDLKTYRQILAFSQGKTLDDLETRIEK
                     AKYPYQKPLIVLGFILAFAVLASLLALIYVRFLP"
     CDS             complement(13083..14774)
                     /locus_tag="ctg14_14"
                     /transl_table=11
                     /translation="MTEKQLIASKLAAVLNDLDQEAIEKLLEKPKNASMGDLAFPAFSL
                     AKVLRKAPNMIAAEVAEQIDASDFEKVQAVGPYINFFLNKSKISNKVLGEVIAKGSQYA
                     SQDLGQGRNIVFDMSSPNIAKPFSIGHLRSTVIGDSLANIVEKLGYNPVRINHLGDWGK
                     QFGMLIVAYKKWGDQQAVEANPISELLKLYIRINAEAEEHPELDDEAREWFRKLEAGDK
                     EAVSLWQWFRDESLVEFNRIYKGLDVDFDSYNGEAFYNDKMDEVVELLEEKGLLQESQG
                     AQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALFRKRTYDFAKSIYVVGNEQAAHFK
                     QLKAILKEMDYEWSDDMQHVAFGLVTKEGKKLSTRKGNVILLEPTIAEAVNRAQSQIDA
                     KNPDLPNKEAVAHAVGVGAIKFYDLKTDRLNGYDFDLDTMVSFEGETGPYVQYAHARIQ
                     SILRKSDFKPNPEAAYSLSDNESWEIIKLIQDFPRVIRRASDNYEPSIIAKFAINLAQS
                     FNKYYAHTRILDDNPERDSRLALSYATATVLKEALRLLGVEAPNEM"
     PFAM_domain     complement(13086..13427)
                     /aSDomain="DALR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05746.17"
                     /description="DALR anticodon binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_14_0019"
                     /evalue="1.80E-32"
                     /label="ctg14_14"
                     /locus_tag="ctg14_14"
                     /protein_end="563"
                     /protein_start="449"
                     /score="112.1"
                     /tool="antismash"
                     /translation="VQYAHARIQSILRKSDFKPNPEAAYSLSDNESWEIIKLIQDFPRV
                     IRRASDNYEPSIIAKFAINLAQSFNKYYAHTRILDDNPERDSRLALSYATATVLKEALR
                     LLGVEAPNEM"
     aSDomain        complement(13086..14762)
                     /aSDomain="TIGR00456"
                     /aSTool="tigrfam"
                     /description="argS: arginine--tRNA ligase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg14_14_0004"
                     /evalue="5.90E-160"
                     /identifier="TIGR00456"
                     /label="ctg14_14"
                     /locus_tag="ctg14_14"
                     /protein_end="563"
                     /protein_start="4"
                     /score="531.3"
                     /tool="antismash"
                     /translation="QLIASKLAAVLNDLDQEAIEKLLEKPKNASMGDLAFPAFSLAKVL
                     RKAPNMIAAEVAEQIDASDFEKVQAVGPYINFFLNKSKISNKVLGEVIAKGSQYASQDL
                     GQGRNIVFDMSSPNIAKPFSIGHLRSTVIGDSLANIVEKLGYNPVRINHLGDWGKQFGM
                     LIVAYKKWGDQQAVEANPISELLKLYIRINAEAEEHPELDDEAREWFRKLEAGDKEAVS
                     LWQWFRDESLVEFNRIYKGLDVDFDSYNGEAFYNDKMDEVVELLEEKGLLQESQGAQVV
                     NLEKYGIEHPALIKKSDGATLYITRDLAAALFRKRTYDFAKSIYVVGNEQAAHFKQLKA
                     ILKEMDYEWSDDMQHVAFGLVTKEGKKLSTRKGNVILLEPTIAEAVNRAQSQIDAKNPD
                     LPNKEAVAHAVGVGAIKFYDLKTDRLNGYDFDLDTMVSFEGETGPYVQYAHARIQSILR
                     KSDFKPNPEAAYSLSDNESWEIIKLIQDFPRVIRRASDNYEPSIIAKFAINLAQSFNKY
                     YAHTRILDDNPERDSRLALSYATATVLKEALRLLGVEAPNEM"
     PFAM_domain     complement(13470..14492)
                     /aSDomain="tRNA-synt_1d"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00750.21"
                     /description="tRNA synthetases class I (R)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_14_0018"
                     /evalue="7.60E-100"
                     /label="ctg14_14"
                     /locus_tag="ctg14_14"
                     /protein_end="435"
                     /protein_start="94"
                     /score="334.3"
                     /tool="antismash"
                     /translation="EVIAKGSQYASQDLGQGRNIVFDMSSPNIAKPFSIGHLRSTVIGD
                     SLANIVEKLGYNPVRINHLGDWGKQFGMLIVAYKKWGDQQAVEANPISELLKLYIRINA
                     EAEEHPELDDEAREWFRKLEAGDKEAVSLWQWFRDESLVEFNRIYKGLDVDFDSYNGEA
                     FYNDKMDEVVELLEEKGLLQESQGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAAL
                     FRKRTYDFAKSIYVVGNEQAAHFKQLKAILKEMDYEWSDDMQHVAFGLVTKEGKKLSTR
                     KGNVILLEPTIAEAVNRAQSQIDAKNPDLPNKEAVAHAVGVGAIKFYDLKTDRLNGYDF
                     D"
     PFAM_domain     complement(14526..14756)
                     /aSDomain="Arg_tRNA_synt_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03485.18"
                     /description="Arginyl tRNA synthetase N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_14_0017"
                     /evalue="2.70E-19"
                     /label="ctg14_14"
                     /locus_tag="ctg14_14"
                     /protein_end="83"
                     /protein_start="6"
                     /score="69.6"
                     /tool="antismash"
                     /translation="IASKLAAVLNDLDQEAIEKLLEKPKNASMGDLAFPAFSLAKVLRK
                     APNMIAAEVAEQIDASDFEKVQAVGPYINFFL"
ORIGIN
        1 taagattatt ttaatgttaa ggacgagtgc ttacctattt gtgtagtcaa tacgtgttaa
       61 cgtagctacc aagcgggtgg ttttgatgaa tgtgctgagt ttattatgac aatcatttgt
      121 ttgcgcctga actcttttga ttggcattag gatagagaga ctctcttttc tttacgccaa
      181 acgtatggaa anatttatgt tttctgatag tgatttttca tcaataatgt catcttttta
      241 gcatcatgct gtaatcaaag taaaatcgag caaataatta gaattggata taaaaagtgg
      301 caatatatta aaaaatgtat gtgtctagaa aatggctaca tgcatttttt tcgtgcgcat
      361 gtcgtatctt ttcttttgat attatcgaaa attttatctg ttcatggtaa aatagattct
      421 attaagtcta gagaaagggg aggtctagag actgtgtctg agtaatgggg catggtctaa
      481 atctttggta acaaggtcaa tcgatgaaat ctgtcattta tcacgatttt ccactgttac
      541 cgaatgtcat gacctctgta tctgatatga tgaagcttca aaaacccaaa ggaacccagg
      601 acatccttcc tgcagatagt gccaaatggc aatatgtgga aaattttgca cgtgagacct
      661 ttaaaaaata caattatggt gaaattcgta caccaatgtt tgaacactat gaagtgattt
      721 cgcgttcggt gggtgatacg actgacattg tgaccaaaga aatgtacgac ttctacgaca
      781 agggtgaccg ccacattacc cttcgacctg aagggacagc acctgttgtg cgttcttacg
      841 tggaaaacaa actctttgca ccagaaatac agaagcctgt aaaaatgtac tacatcggct
      901 ctatgttccg ctatgagcgc cctcaggctg ggcgtttgcg tgaattccac caaatcggtg
      961 tggaggcttt tggttcaagc aacccagcta cagatgttga gacgattgcc atggcttacc
     1021 aactcttcac agaacttggt atcaaggatg ttgtccttca ccttaatagt cttggaaata
     1081 cttctagccg tcaagcttac cgtcaagcct tgattgatta cctgacacca atgcgtgata
     1141 gtctttctaa agatagtcaa cgacgtttgg aggaaaatcc tcttcgtgtt cttgattcta
     1201 aagaaaaaga agataaactt gctgttgaaa atgcaccgtc tattttggat ttcttagatg
     1261 atgagagcca agcgcatttt gatgaagtac gtgctatgct tgaagctctt aatatcccct
     1321 atgtgattga caccaacatg gttcgtgggc ttgattacta caatcacacc atttttgaat
     1381 tcatcacaac cattgagaaa tcagaattga ccatctgtgc aggtggtcgt tatgatggtt
     1441 tggttgagta tttcggtgga cctgagacgc ccggctttgg atttggtctt ggattggaac
     1501 gcttgctaat gattcttgac aaacaaggca ttgagcttcc aattgaatct gatatggatc
     1561 tttatattgc tgttttgggg gctgaagcaa atagcaaagc gttagagctt gttcaagcta
     1621 ttcgcattca gggctttgca gcagagcgtg atgttatcgg tcgtaaaatc aaggcccaat
     1681 tcaaatcagc ggatgccttt aaggccaaaa caattatgac tttaggtggc agtnaagttg
     1741 aggcaggaca agtaactgtt aaaaataata ttacccgtca agagntgacg gtaacttttg
     1801 aagagattag cgaagatttt gcaagcattc tccagaggtt agaagcatag aataatatta
     1861 tttagacatc aaaatcgcta ataatttgtt cttaagtgat tttggtttag tcttggtttg
     1921 taagaggtta ttaaaaataa ctataaaaag cgattcgagt aagattccag aagtttgaaa
     1981 tcttgctcga atcgcttttt tacatgtact ttttgtttca agttgagatg ctactagctt
     2041 atttatttgt aatactatca acgtgaggaa ataaaatggt gattttgtag atgttctcat
     2101 tgatttcttg cttatagagt ccatggtaac ggttaacgat gtctttgata tttcgaagac
     2161 ccaatccatc ataaagtcgt tgttttcgag aatgtgcttc ttgaggatcg aagccatttt
     2221 ctatggcgat atatagtttc tcattgtaaa gattgatgat aagattgatt tttttctcag
     2281 tcgttctttt gtttcggatg actgctgaaa tgctattatc caaaaggttt ccaacgatga
     2341 tagctattat atctgttttt agacgtgtag aggaagggat gagacaactg atggataagc
     2401 agatattatt ttctttggca gtttgcgatt tttggtttag caagtgattt aatatcagtt
     2461 cattggtaaa aaaggtatcg ttagtctcgg taagttgtgc tagattattg ttgatgagtt
     2521 gctcagcctc atcaaatttt tcttgcttta agagacctat tagaacgata tgatggttgt
     2581 gtaggtcgtg ttttaatgct cggactttca ggtgagaatc cttgagattt tgcatattgt
     2641 ggagttgcgc ttgaaatctg atattatcaa gtttggtatt gtaatgatta gtattttgaa
     2701 tcatcatata acgataggtg tacagagaga taatcgttat tgccataaaa ccaaaggagt
     2761 agataagggt tgaggcatcc aattcgtaat gagttgagct atcaaataat tgaaaaaaga
     2821 gtagagcaca ggtgatggca ggaattagcg ataagcagat aatccaagcc ccttgtttat
     2881 ggtggttatc agtatcactg agttcaaaca agaaaaaatg ttttaaataa aaactcatga
     2941 tgatgcttaa aatagctaat aagttaatat aaataaaggt aaatgtcgcc gaatttatca
     3001 aggcatcccc aaagaacagg gttaggctaa agcctagaat ggcttcgaat agaagaccaa
     3061 tagtttgcag aagaattgcc cagaaaagcc cttgttttct gccataatca taaatagaag
     3121 cgatatagaa agaagtgaga aaagagcaga tcacagtgat aagggaagct aagttagtcc
     3181 ttaagaagca gttggctaga acctcaatga ttacaagcac tccaagtgtg agaatggaga
     3241 tgagctggtt gattttttgg ggtgtcgctc ttgagaaaaa atagttgata actaatatgt
     3301 tgatgataga tgtatagaga tgaaataagc ctttaataac cattactgtc tttcaatttc
     3361 attagaatag tatcttgtaa gtgtcgttta aattttcgac taacgggcag gttgataaat
     3421 tgtgactctt gaagaagtgt aatcatttgt ttttcaaatt tgtagaaata gttgacatta
     3481 aagatatagg agttatgaat ttgaataaat tgttgggaaa cttgagcaag aacctccttg
     3541 gttgataaga gagcagtgta ggtttcatac cttgtatgga tataaacctt tctaccgtcc
     3601 ttttcgaaaa aaataatgtc tttaagaggt aatttatagt aggcatgatt gtaggaaaaa
     3661 gtaaaatagt gattggtatt ttccaaaatt ttcaagctac ggttcagaca ctgataaaat
     3721 ctttctctat caagaggttt aagcagataa tcgaaggtct gtacgtgaaa aatctgttcc
     3781 atgtagtcac gatgatttgt taaaaaaatg attatggcat cagcatgttt acttctaatg
     3841 tattctgcca gttcgatacc agagctatct cccatttcaa tatctaaaat aaacaattga
     3901 taatctgtta gtattttttc atacaattta cgaggatgtt catagacgtc taatgaaaaa
     3961 taggaattat ttgagaattt atcaagggca tcttcaacca ttgaaccaac tcccttgtca
     4021 tcatcacata aagcgatacg aatcatcaaa aatctcctcc tgtttgaaaa aaaattatac
     4081 tattgtacca aattttactt aaaaacggct atttttgaca gaattttcta tcgattggga
     4141 agacttgtta aaatagggct atcaattgag gaggaggtag ttattatgcg ggaagtgacc
     4201 gttcgtaaac cgatggaaac agctgaagtt tcatgggtga ttgtttaaat ttataaagta
     4261 ggttgcgcaa tcagcctact ttttatctta atgaggagag gtttgatgat gggatatagt
     4321 aggccacgga taaaaaatat ctacccagta tataaattag ataagaatag atttagaatc
     4381 ggtgctcaaa tgaatattac aagagaattt gaagatccga caggacaatt atgggatttt
     4441 gtaaaaagat tagatggaag agaattacct ctaattgagg ctgatttgca ggcaatctac
     4501 cctgaggtaa cacatgatga tattgtattc gctttggaat tattagacaa agaaggtttt
     4561 atagaagagt atcaggatgt taaccttgtg gaagaacggt atatgtcgaa tgttaattat
     4621 tttagacgct atcttggtag ctatgatgaa agtttaactg tacaaagaaa actaaatgaa
     4681 agttcaattt tattattggg tctgggggga ggaggctcta atattttaag tttactagct
     4741 ggcataggtc ctaaaaaatt aacaattgta gattatgata aagttcaaat ttaggaaggc
     4801 aattgctgta taaagaagat gatataggga aattgaagac agaaacggct ttaagagagt
     4861 ttcagaagat gaattcatct gttagcataa atgccattac taaaaaaatt acttctgtgt
     4921 ctgatgtagt agaattactt gatggcattg atctggttat ttgtgcaata gacgaaccgc
     4981 cttttgtagc acaaagaata gttaataaag ccattgttaa agtaggagta ccttgtgtct
     5041 ttggagggtc gcaagtaagt agggatcgag tttatagtgt tattccaaaa aaacaggatg
     5101 ctttgactgt ctaaatatcc attatacaaa gacgtctcct aactttatag atcaatttat
     5161 tggctttcag aaaattaaat ttgatcctcc cacaatagct tatgcacctg caattcttca
     5221 gttatgtagt gctatagttg atgaatcagt aagactttta acaaaatata ctgaaccaat
     5281 gagtttaagt acacaatttg agattaatta tgaaacaggt gcttcgttct gtcataaacc
     5341 atggcctaga tatgaagatg agtgcccaac ttgtggaaaa ggaactattt ctgagtggga
     5401 aatttttaat cattataatt catgatggta agaaggaata gaatatgaag aattgtttag
     5461 cagtgacgaa tatctctaaa agatacgcta aggggaaaca gtttgcaaac aaagagttga
     5521 attgtgaatt caacgaagga gaaatcacag ctttaatagg gcataatggt gcaggaaaaa
     5581 ccaccttgtt gaatcaaatc atcggtataa cagattcaga taagggagac atctcctatt
     5641 tacaagaatc gtttacgaaa tctcccaagc tagctagatc ttacacttca atgatgccgc
     5701 aaatgcatgc ccctttgaaa ggagtaagtg tgaggcaagc cataagctcg attggaggca
     5761 tccgagggat agatccagct gctttaaaag atgaagttga tgatatttta gaggcattag
     5821 acatcacaaa atgggagaat caaaaaggag aaaagctatc aggtggactt aaacgcctaa
     5881 cttcatttgc catggcgatt gttggtgctc ctaaaatcat tttgctggat gaaccgacaa
     5941 atgatgtgga tccgatgaga aggactcgcc tatggttata tcttagaaag ttggcttcaa
     6001 gagggcatat tcttatcatt gtgacacata atattttaga agtagaaaaa tacgctgata
     6061 agtattatat gttggaacaa ggagaagtaa aggcaagtgg aaacgtcaaa tcgcttgaga
     6121 acatggcagg tcacttagtt cgtttcacgg tatactctca aaaaacaatg gagagttttc
     6181 ccttagactg tactatcagt gatagtttgg aggtttcagc aaggattgaa acacccgatt
     6241 tacccgtatt attgacttgg ttgcaggatg ctatcatagc taagacgatc agtaactacc
     6301 acctatctac actaggctta aatgattatt atgaggttct atccaatgaa aagtaattat
     6361 caacagatac gaggtttgtt aatttggagt tatgtcagaa ataaatctct aataatactt
     6421 tgtagtattg tccaattttt catgtctatt gctctgattt atggctattc attaattgtg
     6481 gaacccagaa ctccagaagc gcaactttat ttggcttcag gtgcagtgac tttaggtatg
     6541 ataacaatag gctgtaccat tgctgcgcaa actatcagta gcgcaaagca agatggactc
     6601 gtaacctact tgaaaacctt acctgtaaaa agaagtttta ttctcttttc tgaactgttt
     6661 atttgggcta tcgtttcttt tttgggtgtc atcctatctc taatcacagt ctttgtaaaa
     6721 tttcaatttt taccacagct gtctattggg agttttgggc ttctatggtt aatcctatta
     6781 accatgctat caataggatt tgctattgcc tattcgacct caccaagtgc catgtcttta
     6841 atcactcaat taatcctcat gattggctta ctattttcac ctataatgtt tcccgcagat
     6901 agaatacctg cctttttact aaggctgtac agccttctcc cctttgtccc tgctggaaat
     6961 ctcattaggt tatctgtcta tcaagattat cctgtggctg ctcgtgacat ttttgtttta
     7021 ttgttttggt tgctcttgac gagttcactc tcagtgtggc aactacaccg aaaagtatga
     7081 tcatcattta tagtgatgat agggaatccc tagagtaaag gattgttttt ctcaaaactc
     7141 cgcctaaaag ggtggggttt ttaagtgctt tttgctataa tgataaggaa tgatacgcag
     7201 gtcttgcgtg tgaaatactg atatacggag aataaaatga ctgaacgtag tatgtatgct
     7261 ggtcgtgttc gtagtgaaca cattggaact gaaatcaccc tcaaaggttg ggtaggtcgt
     7321 cgtcgcgatc taggtggatt gatttttatt gatttgcgtg accgtgaagg gattatgcag
     7381 ctggtgatca atcctgaaga agtttcaagt gacgtgatgg caactgctga aagccttcgt
     7441 aacgaatatg ttattgaggt tacagggact gttgaagcgc gccagcaggc taacgataat
     7501 cttgcaacag gtgcggttga gttgaaagta agcgccttga gcgttcttaa tgttgcaaaa
     7561 acaacacctt ttgaaataaa agacggtgtg gaagtttctg atgataatcg tcttaaatac
     7621 cgttatttgg atcttcgtcg tccagaaatg ttggaaaact tcaaactacg tgctaaggtg
     7681 acacattcta tccgtaacta tttggatgag cttgaattta ttgatgttga gacaccaatg
     7741 ttgactaagt caacgccaga aggtgcgcgt gactatcttg tgccatctcg tgtcagccaa
     7801 ggtcattttt acgcacttcc acaaagccca caaatcacga aacaattatt gatgaatgct
     7861 ggttttgatc gttactatca aattgttaag tgtttccgtg atgaggactt gcgtggagat
     7921 cgtcaaccgg agtttacaca ggtcgattta gaaacgtcat tccttaacga gcaagaaatt
     7981 caagacatcg ttgaaggtat gattgctaaa gtcatgaaag atactaaggg aattgaggta
     8041 accttaccat ttccacgtat ggcttatgat gacgctatga atctttacgg ttcagacaaa
     8101 ccagatactc gttttgacat gcttttacaa gacttgacag atattgtcaa ggacgttgat
     8161 tttaaagtct tctcagaagc tccagcggtt aaagcaattg tcgttaaagg aagtgcggat
     8221 aagtattcac gtaaagacat cgacaagatg acagaatttg ctaagcaatt tggtgccaaa
     8281 ggtctcgcct gggtcaaggt aacagacggt gctatcgctg gtcctgttgc taaattcttg
     8341 acaaatatcg aagatgactt gacagcagct ttacaacttg aagaaaatga tttggtgcta
     8401 tttgttgcag ataagcttga agtagctaat gatacacttg gtgctttacg tggacgtatt
     8461 gccaaagaac ttgacatgat tgacaactct aaattcaact tcctttgggt tgtcgattgg
     8521 ccaatgtttg aatggtctga agaagaagga cgctacatgt cagcccatca tccattcacc
     8581 ttgccaacag aagactctgc tcatgagctt gaaggtgatt tagccaatgt tcgtgcagtt
     8641 gcttacgaca tcgttcttaa tggttatgaa ctcggtggag gtagtcttcg tattaaccaa
     8701 aaagatatgc aagaacgcat gcttaaggcg cttggctttg cagaagaaga tgcctatgag
     8761 caatttggtt tcttattaga agctatggat tacggtttcc ctccacatgg tggtttggca
     8821 atcggtcttg accgctttgt catgcttcta gctggcaagg ataatatccg tgaagtgatt
     8881 gccttcccta aaaacaataa agcgactgac cctatgacgc aagcaccaag tgtggttgct
     8941 gacaaacaac ttgaggaact agccctacaa ttacagttaa atgactaaaa aaacgacttt
     9001 tcttaaaaga gtaagatacg aagtaaatgt tgtagccaag cgatttggtt tgtggcgtac
     9061 cttacgaagt atttctagag aaaaatatgc agagaagatt tcagcttctc tgctttatgg
     9121 tatgttatct agtatcgctg tgaatttctt tttccagccg ggtcatgtct attcaagtgg
     9181 tgcgacaggt ttggcacagg ttatatcagc cctgacggag agaagtttcg gttatgcaac
     9241 gccaatttcc ttgacttttt atgccatcaa cctcccactt ttgattttag cttggtacac
     9301 aatcggtcat aaattcaccg tcttcacctt tatggcagtt tctatgagtt ctttatttat
     9361 tcatctcatg ccacaggtga ctttgacaac tgatcctctg attaatgcca tttttggtgg
     9421 tttattcatg ggtctgggag ttggtgtcgg gcttcgctct agaatttcta gtggcggtac
     9481 cgatattgtt tccttgacta tccgtaaaaa aacaggacgt aatgtgggca gcatttccct
     9541 gtttgttaat ggagttatta tgatttttgc cggtcttctt tttggctggc aatatgccct
     9601 ctactctatg ataaccattt ttgtgtcaag tcgtgtcact gatgcgattt ataccaaaca
     9661 aaagaaaatg caggccatga ttgttacatc aagacctgat cgtgtggttg ctatgattca
     9721 taaaaaattg catcgtggcg tcacatcgat aaatgatgct catggtactt ttaaacatga
     9781 agataaggca gtgctcttag caatcatcac aagggaagaa tacacagaat ttaaacaact
     9841 aatggcaaaa gcagatcccc gagcttttgt gtctatctcg gaaaatgttc agataatcgg
     9901 aagatttaac gatgattaaa aagctcgacg gaaccatttg gacccaagtc tagaaataag
     9961 ggagacaatc tggcgacttt tctctctggt gcttggaagt ttttggatat atgataaggt
    10021 aaaaggagct actggctctt tttatgacgg cgaaatgaga aattaatctt taaaaaaata
    10081 agattttata ctcaatgaaa attagactca gaccaggtgg cgccgatgca gataaaactg
    10141 tcttcatcaa accaagtcaa caaggtctga atttgatttt tgaagagcat tgtattaaga
    10201 agaggtgagg tatgaaattt agatggcacc tttcggatgg tattcatctg atttggatta
    10261 cattgggtgt agctctttac acatttggat ttgtgaattt caatatggca aaccatctag
    10321 cagaaggtgg ggtagcggga atcactttga ttttacatgc tctttttggt ttggatcctg
    10381 ctctatcgtc tttgcttatt aatatacctc tttttgtatt gggggctcgt gtttttggaa
    10441 agaaatcact gctactaacc atttatggta ctgtaaccat gtctattttt atttggattt
    10501 ggcaacgtgt tcccatggag cttggtttac aggacgatat gatgctagtc gcgattgtcg
    10561 ctggtatttt tgctggaatt ggtagtgggg ttgtctttcg ttatggtgcg acaactggtg
    10621 gtacagacat tgttggacgt gttttggaag aaaaaacagg gatgaagctg gggcaaacct
    10681 tactgatgat tgatgttttg gtgttagcat cctctttagt ttatattgac ctaaaacaca
    10741 tgctttatac tttgatagcc agttttgttt ttagccaagt tctgacggtt gtgcaaaacg
    10801 gtggttatat ggttcgtggt atgctgatta ttaccaagga gtcagataaa gcttcggcag
    10861 caattttaca agaaattaat cgcggggtaa cttacctgca aggaaaagga gcttatactg
    10921 gacgtggctt tgatattctc tacgtggttt tgaatcctaa cgaagtgcgt gaggtcaaag
    10981 atatattggc agaattagac ccagatgcct ttatttcaat tcttaatatt gatgaagtga
    11041 tttcatcgga ttttaaaatt ataaggaaaa attacgataa agagttataa aaaagcctct
    11101 ttgtcaaccg tagtgagtga cttataatag ctaagcatcg tcttttatac taacttgaca
    11161 catggtcact ttcgacttgc cgtactcata ctcaatgaaa atcaaaagca gactaggcgg
    11221 cgccgatgcc gatagaacta aagttcatca aatcaagtca acaaagtctg cttttgattt
    11281 ccgaagagta tcaagcactg tccgtgtctt tttgctcctt atctgaaagt taatttattt
    11341 gattatacca gaggagacct tatcgtcttc tcttttttgt gttaaaagca ccgttttaga
    11401 gggtaagcag gctttaaata tccagaatgg agattgttaa tggtttatga aaatcgtatt
    11461 taatcatgtt tgcttggcaa tgaagacata aggaagctgg ataagccagt ttcgcactga
    11521 tatgagattg tttttaacaa gcaaatggct gatatttgag tcttttagtc tcaataatta
    11581 aggagctcag atggtgcttt ctaaggagag tgtagggctt tttattataa gccatatggg
    11641 actttcatat aatcaaaaag ccccataatc tccagagtgg ggttacccac tacggaaatt
    11701 acagagccta gataaactta tctagcttct ttacttgcat cgtagtcaac accgatgata
    11761 gtcacatcga tattaccacg tgttgcttta gagtaaggac acacttcatg agctttttca
    11821 ccgagttctt tggcttcatc tgctgattta ccatcaacag aaacttcgat ttcaacaccc
    11881 agtttgaaat cagcaccgtc tgctttgaaa agttgtgtgc gttgggtaat cattgactta
    11941 gctttgatat tttctagtcc aagtacaact tccaaggcac tattgaaaca agctgagtaa
    12001 ccaagtgcaa acaattgttc aggatttgta ccattgccgt cgccccccat ttctttaggg
    12061 cttgagattg tgacttgaaa actactgttt tcaacatagc taataccgct acgtccacca
    12121 gtgttaacag cagaagtttc atagattttt tgataatttg acatatcagt accccccata
    12181 tctaatgtta ttataacact ttcaaggtca aaaggcagac tagttgttta ttgatttgaa
    12241 aaataggctt tagtgaagtt tttcgcagaa aaaggcgctt aagttgacaa ttttgtaaag
    12301 gtaatgcttc aaatcgtttg tcaaaatatt ttgacaaccc ttttttatgt cgtatcaaaa
    12361 agatttggta gaatagattt aataaaagct atagactaag agtgaccaag gaaatcagga
    12421 aatttgtagc agattttaga aaggaggtat cacttggaag ttggaaaaaa tattaaaagt
    12481 tatcgccagc agttcaattt atctcaggag ggtttggcgg agaagattta tgtgactaga
    12541 caaacgatct ccaactggga gactgaaaag tcctatccag atgttcactc gctcgtctta
    12601 cttagtcatt gttttaaggt ttccttggct caactaattg aaggagatct cgataaaatg
    12661 aaaaaaattg ttaagaaaga agatatcgat cttatggatt gctataccaa aaagatgatg
    12721 tgggcaatgt tagctctctt gtttactgtg tttcctgctt tttattattt agattggtgg
    12781 ggaatgctag tttatcttcc tttagcagct tttggaattt attatgctca taaggttgaa
    12841 aaaataaaag acaattatga tttgaaaact tatcgtcaaa ttcttgcctt tagtcaagga
    12901 aaaactttgg atgatttaga gacaagaatt gaaaaagcta agtaccctta tcaaaagcct
    12961 ttgattgttc ttggtttcat tctagctttt gcagttttag cctctcttct tgccttgatt
    13021 tatgtgaggt tcttaccata atgtaaaaaa cacgcccgtg agggtcgtgt tttttcatac
    13081 tattacattt cgtttggtgc ttcaacgcca agaagacgaa gagcttcttt aagaacagtt
    13141 gctgtcgcgt atgaaagtgc taggcggctg tcacgttctg gattgtcatc aagaatacgt
    13201 gtgtgtgcat agtatttgtt gaaactttgt gccaaattga tggcaaattt agcgatgatt
    13261 gatggctcat agttgtctga tgcacgtctg ataacacgtg ggaagtcttg aatcaacttg
    13321 ataatttccc agctttcgtt gtcagatagg ctgtaagcag cttctggatt tggtttgaaa
    13381 tcagatttgc gcaagattga ctgaatacgt gcatgagcgt attgaacgta aggtccagtt
    13441 tctccctcga aggaaaccat ggtatcaagg tcaaaatcat agccattcag acggtctgtt
    13501 ttaagatcgt agaatttgat agctccgaca ccgacagcgt gagcaacagc ttctttattt
    13561 ggaagatcag ggtttttagc gtcaatttga gactgggcac gattaacagc ttcagcaatg
    13621 gtcggttcta gaaggatgac attaccttta cgagttgata attttttacc ttctttagta
    13681 acaagaccaa aagcaacatg ttgcatatca tctgaccatt cgtagtccat ttctttaaga
    13741 atggctttaa gttgtttaaa atgtgctgcc tgctcgttcc caacgacata gattgattta
    13801 gcaaaatcgt aggtacgctt acggaaaagg gctgccgcca agtcacgtgt gatataaagt
    13861 gttgctccgt ctgatttttt aatcaaagct gggtgttcaa taccgtattt ttcaagatta
    13921 acaacttggg caccttgtga ttcttgaagg aggccttttt cttctaaaag ctcaacaact
    13981 tcatccatct tgtcattgta gaaggcttca ccattgtaag agtcaaaatc aacgtcaagt
    14041 cctttgtaga ttcggttaaa ttcaacaaga ctttcgtcac ggaaccattg ccagagggag
    14101 acggcttcct tatcacctgc ttcaagttta cggaaccact cgcgtgcttc gtcatcaagt
    14161 tctggatgtt cttcagcttc tgcattgata cgaatgtaaa gtttgagaag ttctgagatt
    14221 ggattggctt caactgcttg ttgatctccc cattttttat aagcgacaat gagcatccca
    14281 aactgtttac cccaatctcc gaggtgattg atacgcacag gattatagcc taatttttct
    14341 acgatgtttg ctagactatc tcctataaca gttgagcgca agtgtccaat agagaatggt
    14401 ttagcgatat tggggctaga catatcaaaa acaatattgc gtccttgtcc aagatcttgg
    14461 ctggcgtatt gacttccttt tgcgatgact tctcccaata ctttgtttga aatcttagat
    14521 ttatttaaga aaaagttgat gtaagggcca actgcttgta ctttttcaaa gtcagaagca
    14581 tcgatttgtt cggcaacttc agcagcaatc atatttggtg ctttgcgaag gactttagct
    14641 aatgaaaatg ctggaaaggc aaggtctccc atgctagcat ttttaggttt ttcaagtagt
    14701 ttttcaattg cttcttgatc caggtcattt aacactgcag caagttttga agcgattagt
    14761 tgtttttcgg tcatgatgtc tcctttggtt ttat
//
