LOCUS       NZ_KB904598.1          20939 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KB904598.1 Streptococcus thoraltensis DSM 12221
            A3IADRAFT_scaffold_2.3, whole genome shotgun sequence.
ACCESSION   NZ_KB904598
VERSION     NZ_KB904598.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:47:09
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 193643
            Orig. end    :: 214582
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20939
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[198643:209582]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..15939
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..20939
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20939
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1569..1892)
                     /locus_tag="ctg13_157"
                     /transl_table=11
                     /translation="MSKKLKAELKNELMKVLNDYHVQRNGDLNLLFENCMAELENAKTN
                     RDVSAITARLSQSISYYLVCHRYEAPKSVIDLGLWLAKYPSVERGHLAPLQMLAQSLAG
                     LLR"
     PFAM_domain     complement(1650..1874)
                     /aSDomain="EntA_Immun"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08951.12"
                     /description="Enterocin A Immunity"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_157_0001"
                     /evalue="5.80E-09"
                     /label="ctg13_157"
                     /locus_tag="ctg13_157"
                     /protein_end="81"
                     /protein_start="6"
                     /score="36.2"
                     /tool="antismash"
                     /translation="AELKNELMKVLNDYHVQRNGDLNLLFENCMAELENAKTNRDVSAI
                     TARLSQSISYYLVCHRYEAPKSVIDLGLWL"
     CDS             complement(1885..2217)
                     /locus_tag="ctg13_158"
                     /transl_table=11
                     /translation="VAILYRNEPVLVWKVNRIEPYPDWVQEAFDKNIMVWIDHHVRILM
                     AALQPSAIENAKTGAVGAMAGGFGGYGMYVLAYPGDYLDVTNHRVISEKTFQKEYQLVE
                     GEETNV"
     CDS             complement(2234..2542)
                     /locus_tag="ctg13_159"
                     /transl_table=11
                     /translation="MTNDREQMLIRVYNLILDPSVSQEERDILRAFMSDLERGSDYQVS
                     VMRFAEDLRQLAVKNLKDYKKLSPNVARLYREIAYRGEKYSNIAKGLMSIGLWGLGK"
     PFAM_domain     complement(2309..2530)
                     /aSDomain="EntA_Immun"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08951.12"
                     /description="Enterocin A Immunity"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_159_0002"
                     /evalue="9.30E-13"
                     /label="ctg13_159"
                     /locus_tag="ctg13_159"
                     /protein_end="78"
                     /protein_start="4"
                     /score="48.4"
                     /tool="antismash"
                     /translation="REQMLIRVYNLILDPSVSQEERDILRAFMSDLERGSDYQVSVMRF
                     AEDLRQLAVKNLKDYKKLSPNVARLYREI"
     CDS             3356..3589
                     /locus_tag="ctg13_160"
                     /transl_table=11
                     /translation="MIDDFIEVFDITRSLYQAGCPYDNAVSESNYHSFKIEFIKQETFH
                     TLEESILKPRNMFTGGTSTAPYSQQFLAIKHQ"
     CDS             complement(3705..4388)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_161"
                     /sec_met_domain="Abi (E-value: 4.2e-18, bitscore: 59.2,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKDKSLFNIIAMGLIMFFHLSIPKCLDILFPFYGFYSDLYYLYY
                     VLLDTVTIILAYLLFKQVNNEELYQNKLLTLENIRILCISLLGIYSVEYFLIKHLTNST
                     ANSQAINDFLYYSTGKYYSYLFLLLICLLGPIVEELIYRGLLMNALFRKSTYGIDILIS
                     ACLFSMIHIYKYPWSTIAFFIYFVYGLGFAMIYHYSRNLKLSMVAHVAVNTFISIPYII
                     YVFTN"
     PFAM_domain     complement(3747..4019)
                     /aSDomain="Rce1-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02517.18"
                     /description="Type II CAAX prenyl endopeptidase Rce1-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_161_0003"
                     /evalue="3.40E-16"
                     /label="ctg13_161"
                     /locus_tag="ctg13_161"
                     /protein_end="214"
                     /protein_start="123"
                     /score="59.5"
                     /tool="antismash"
                     /translation="YLFLLLICLLGPIVEELIYRGLLMNALFRKSTYGIDILISACLFS
                     MIHIYKYPWSTIAFFIYFVYGLGFAMIYHYSRNLKLSMVAHVAVNT"
     CDS             complement(4390..4527)
                     /locus_tag="ctg13_162"
                     /transl_table=11
                     /translation="MNTKIVEQFEMMDEMVLSSVEGGIQVPWYDYMIFPRDISSAPWNK
                     "
     CDS             complement(5001..5210)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_163"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.7e-11,
                     bitscore: 37.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNTIEQLEVMANLNLENTVGGYSAGACFTDIVLVAIDGIASGAA
                     GGALSAGVGCFIAGAQEISDGLFK"
     CDS             complement(5712..6386)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_164"
                     /sec_met_domain="Abi (E-value: 6.3e-13, bitscore: 42.6,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKKTSIYLFPVFIYIVFHNILAQIQLYWWKQRNFDDNFYLLVNA
                     ILLLNILIICLWQSTRFNSKPFRIFGAKWWYAPITFCLGSAIFIFDLTSSRLFSIPLTE
                     NTNSLNTILSYSNGNFFLQGFILWNVILGPIREEIFNRMLLMETYFKESPYYFDVLLSA
                     IVFSASHVLPSGNFQAFWVYAIPGTLYALMYRFTRTIYCPILVHILWNGYVYWDLINLV
                     IT"
     PFAM_domain     complement(5751..6014)
                     /aSDomain="Rce1-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02517.18"
                     /description="Type II CAAX prenyl endopeptidase Rce1-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_164_0004"
                     /evalue="3.70E-11"
                     /label="ctg13_164"
                     /locus_tag="ctg13_164"
                     /protein_end="212"
                     /protein_start="124"
                     /score="43.3"
                     /tool="antismash"
                     /translation="FILWNVILGPIREEIFNRMLLMETYFKESPYYFDVLLSAIVFSAS
                     HVLPSGNFQAFWVYAIPGTLYALMYRFTRTIYCPILVHILWNG"
     CDS             complement(6399..6524)
                     /locus_tag="ctg13_165"
                     /transl_table=11
                     /translation="MKIYEEIATEKLLDINGGVMLPWHDYGLILSPKSSVDAVLK"
     CDS             complement(7110..7313)
                     /locus_tag="ctg13_166"
                     /transl_table=11
                     /translation="MKKKYKELATNDIANISGGNPTGNAAIGGLSGLSAGIKYCKIPHP
                     VLKGVCVVGVTAGSAYLAYKVN"
     CDS             complement(7647..8012)
                     /locus_tag="ctg13_167"
                     /transl_table=11
                     /translation="MDKLKRLLQFGFLLCLTIDLTVFYLFFRTIRVEESHLTVYFLLLT
                     ILHVLVVLWAYAMLKRYKVNYVFLKQQMKIALLVVVASVLVVVPLFILKEDTIPMAMLL
                     TNSVIFFLYPNRRGYIS"
     CDS             complement(8041..8271)
                     /locus_tag="ctg13_168"
                     /transl_table=11
                     /translation="MGTIITQMVILIVFLLYILISISLKKFHGKIYRACTFIFIIAGMV
                     SYVTKGSNWFDFLALLIPLMVLYQFEDRFTK"
     CDS             complement(8512..8763)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_169"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.4e-08,
                     bitscore: 27.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSKSIISFQEIQLESLSNVNGGANKWNNAATGAVYGAGIGVSLC
                     TAAGMMTAGATLAATAGCAWAGAKIGGSIAFIADNIIK"
     CDS             complement(9000..9173)
                     /locus_tag="ctg13_170"
                     /transl_table=11
                     /translation="MKKILIIAIQILVSAPLIYYIRETFGIYSFIHWGLFLLIYLVNLI
                     IYKKICQKITPK"
     CDS             complement(9185..9370)
                     /locus_tag="ctg13_171"
                     /transl_table=11
                     /translation="MRQAELQSAELETIVGGKVCSVFDIFCVIGEGIKSGSKGPVKPPT
                     CSYPSAWNPAPVIRCY"
     CDS             complement(9389..9577)
                     /locus_tag="ctg13_172"
                     /transl_table=11
                     /translation="MNTKAMEKFNDLNSADLATVEGGDGGASLLWFLVGGVYSYYANEA
                     TASCRKNPKQWHCINIK"
     CDS             complement(9796..10485)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_173"
                     /sec_met_domain="Abi (E-value: 8e-19, bitscore: 61.5,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGVFKKCFRLALSIIFFMVMIMFIQTPVISTLSKDHVNFKQDTQ
                     GDILRVMTCIGAIILSLYFLRLLAKCLGINLSKPQSKRRLFNDKRLLAYIVVILLITLI
                     YLILLFIGNGYSVGVVPKEISEMSNKPVIFILYMFTTIISQPILEELLFRGILQERLAR
                     YSSWISIIITSIVFSYIHGYGAIINSQFISSIIYGIIYKSSDDVRFPIIIHSLQNLVVV
                     LFVIVFA"
     PFAM_domain     complement(9826..10083)
                     /aSDomain="Rce1-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02517.18"
                     /description="Type II CAAX prenyl endopeptidase Rce1-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_173_0005"
                     /evalue="2.20E-16"
                     /label="ctg13_173"
                     /locus_tag="ctg13_173"
                     /protein_end="220"
                     /protein_start="134"
                     /score="60.1"
                     /tool="antismash"
                     /translation="ILYMFTTIISQPILEELLFRGILQERLARYSSWISIIITSIVFSY
                     IHGYGAIINSQFISSIIYGIIYKSSDDVRFPIIIHSLQNLV"
     CDS             complement(10501..10665)
                     /locus_tag="ctg13_174"
                     /transl_table=11
                     /translation="MSQKELSHKELEKILGGAPVINLGADVIKVVNKLFAGTCSFIDGV
                     NGKKYKGKC"
     aSDomain        complement(10615..10656)
                     /aSDomain="TIGR01847"
                     /aSTool="tigrfam"
                     /description="bacteriocin_sig: bacteriocin-type signal
                     sequence"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg13_174_0001"
                     /evalue="3.80E-03"
                     /identifier="TIGR01847"
                     /label="ctg13_174"
                     /locus_tag="ctg13_174"
                     /protein_end="17"
                     /protein_start="3"
                     /score="15.8"
                     /tool="antismash"
                     /translation="KELSHKELEKILGG"
     CDS             complement(10720..10887)
                     /locus_tag="ctg13_175"
                     /transl_table=11
                     /translation="MNTKVYKQFPELSGDTLENITGGDDFTRGMYKLGRAVRDTVNKTG
                     KFICDRAPWC"
     CDS             complement(11517..11717)
                     /locus_tag="ctg13_176"
                     /transl_table=11
                     /translation="MNTKIVEQFEVLNVESLSVVEGGALPLGPVIKGLGIYVAGKIFDG
                     VGKDSTKSCQQNPKQWFCFKV"
     CDS             complement(11991..12200)
                     /locus_tag="ctg13_177"
                     /transl_table=11
                     /translation="MIYTVFIVLSSSIIVFTTIHAIYRKSVTHLTPYLFFLVFYQLSLS
                     KQTTNMLSIVTLLASLLVYFDKKD"
     CDS             complement(12201..12401)
                     /locus_tag="ctg13_178"
                     /transl_table=11
                     /translation="MKKYKELATNDIANISGGNPTGNAAIGGLSGLSAGTKYCKIPHPV
                     LKGVCAVGVTAGSAYLAYKVN"
     CDS             complement(12648..12944)
                     /locus_tag="ctg13_179"
                     /transl_table=11
                     /translation="LSIVKWFSGGKERKDKASELIQDLILDLKNSPNTKQLEQLLVSYK
                     KELDEEKSSVPFILSRLNVSISKIISENNISLTKSQADILKKIRTLSHIRYGY"
     PFAM_domain     complement(12681..12884)
                     /aSDomain="EntA_Immun"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08951.12"
                     /description="Enterocin A Immunity"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_179_0006"
                     /evalue="2.00E-10"
                     /label="ctg13_179"
                     /locus_tag="ctg13_179"
                     /protein_end="88"
                     /protein_start="20"
                     /score="40.9"
                     /tool="antismash"
                     /translation="IQDLILDLKNSPNTKQLEQLLVSYKKELDEEKSSVPFILSRLNVS
                     ISKIISENNISLTKSQADILKKI"
     CDS             complement(13327..13557)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_180"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4.7e-12,
                     bitscore: 39.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTNTLEQFTMMDEMVLSSIEGGKCTWSGLGKAAIGTGAGNGLRM
                     GIKTGTWQGAIGGAAGGAIIGGVGYGATCWW"
     PFAM_domain     complement(13366..13542)
                     /aSDomain="Bacteriocin_IIc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10439.11"
                     /description="Bacteriocin class II with double-glycine
                     leader peptide"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_180_0007"
                     /evalue="5.90E-08"
                     /label="ctg13_180"
                     /locus_tag="ctg13_180"
                     /protein_end="64"
                     /protein_start="5"
                     /score="32.7"
                     /tool="antismash"
                     /translation="LEQFTMMDEMVLSSIEGGKCTWSGLGKAAIGTGAGNGLRMGIKTG
                     TWQGAIGGAAGGAI"
     CDS             13788..14567
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_181"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.8e-44, bitscore:
                     143.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYKRTFIPQVDARDCGVAALASIAAFYGSRYSLAHLRELAKTN
                     KEGTTALGLIKAAQEIGFETRAIQADASLFDMTDVPYPFIAHVNKEGKLQHYYVVYQTT
                     KKGLIIGDPDPSVKVTKMSYDTFLSEWTGVALFMAPKPSYQPHKDKKNGLASFLPLIFK
                     QKAVIAQIVIASLLVTVINIVGSYYLQSILDDYIPNHMLSTLGIISVGLIITYIIQQIM
                     TFARDYLLTVLSQRLTIDVILSYIKHIFNLPMSFFCD"
     PFAM_domain     13806..14213
                     /aSDomain="Peptidase_C39"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03412.17"
                     /description="Peptidase C39 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_181_0008"
                     /evalue="2.70E-42"
                     /label="ctg13_181"
                     /locus_tag="ctg13_181"
                     /protein_end="142"
                     /protein_start="6"
                     /score="143.8"
                     /tool="antismash"
                     /translation="TFIPQVDARDCGVAALASIAAFYGSRYSLAHLRELAKTNKEGTTA
                     LGLIKAAQEIGFETRAIQADASLFDMTDVPYPFIAHVNKEGKLQHYYVVYQTTKKGLII
                     GDPDPSVKVTKMSYDTFLSEWTGVALFMAPKP"
     PFAM_domain     14298..14558
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_181_0009"
                     /evalue="5.60E-15"
                     /label="ctg13_181"
                     /locus_tag="ctg13_181"
                     /protein_end="257"
                     /protein_start="170"
                     /score="55.8"
                     /tool="antismash"
                     /translation="IVIASLLVTVINIVGSYYLQSILDDYIPNHMLSTLGIISVGLIIT
                     YIIQQIMTFARDYLLTVLSQRLTIDVILSYIKHIFNLPMSFF"
     CDS             14506..15939
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 294.8; E-value:
                     2.2e-89)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_182"
                     /sec_met_domain="TIGR01193 (E-value: 9.4e-222, bitscore:
                     731.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFYLISSTSLTCPCLFFATRRTGEIISRFTDANAIIDALASTIL
                     SLFLDFSIVIIVGSVLLLQNPNLFFLSLVSIPIYLVIIFAFMKPFERMNNDVMQSNSMV
                     SSAIIEDINGIETIKSLTSEEIRYQKIDREFVDYLDKSFTLSKLSTLQSALKQGAQLLL
                     NVLILWLGSDLVIKGKISVGQLITFNTLLSYFTDPLENIINLQTKLQSAKVANTRLNEV
                     YLVDSEFKDQTFETDPATLKGDIVFDQVSYKYGFGRDTLSDITITIKEKTKVALVGISG
                     SGKTTLAKMIVNFYEPYQGTIRLNGTDLKTLDKKVLRRHINYLPQQAYIFNGSILENLT
                     LGIKETVSQEDILKACEIAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTK
                     APTLILDEATSGLDVLTEKKVIDNLLALDKTIIFVAHRLSIAQRAEKILVLEQGKVVEE
                     GSHRDLVRRQGFYYHLFSK"
     aSDomain        14539..15933
                     /aSDomain="TIGR01193"
                     /aSTool="tigrfam"
                     /description="bacteriocin_ABC: ABC-type bacteriocin
                     transporter"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg13_182_0002"
                     /evalue="2.20E-220"
                     /identifier="TIGR01193"
                     /label="ctg13_182"
                     /locus_tag="ctg13_182"
                     /protein_end="476"
                     /protein_start="11"
                     /score="731.8"
                     /tool="antismash"
                     /translation="TCPCLFFATRRTGEIISRFTDANAIIDALASTILSLFLDFSIVII
                     VGSVLLLQNPNLFFLSLVSIPIYLVIIFAFMKPFERMNNDVMQSNSMVSSAIIEDINGI
                     ETIKSLTSEEIRYQKIDREFVDYLDKSFTLSKLSTLQSALKQGAQLLLNVLILWLGSDL
                     VIKGKISVGQLITFNTLLSYFTDPLENIINLQTKLQSAKVANTRLNEVYLVDSEFKDQT
                     FETDPATLKGDIVFDQVSYKYGFGRDTLSDITITIKEKTKVALVGISGSGKTTLAKMIV
                     NFYEPYQGTIRLNGTDLKTLDKKVLRRHINYLPQQAYIFNGSILENLTLGIKETVSQED
                     ILKACEIAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAPTLILDEATS
                     GLDVLTEKKVIDNLLALDKTIIFVAHRLSIAQRAEKILVLEQGKVVEEGSHRDLVRRQG
                     FYYHLFS"
     PFAM_domain     14542..15102
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_182_0010"
                     /evalue="6.50E-41"
                     /label="ctg13_182"
                     /locus_tag="ctg13_182"
                     /protein_end="199"
                     /protein_start="12"
                     /score="140.9"
                     /tool="antismash"
                     /translation="CPCLFFATRRTGEIISRFTDANAIIDALASTILSLFLDFSIVIIV
                     GSVLLLQNPNLFFLSLVSIPIYLVIIFAFMKPFERMNNDVMQSNSMVSSAIIEDINGIE
                     TIKSLTSEEIRYQKIDREFVDYLDKSFTLSKLSTLQSALKQGAQLLLNVLILWLGSDLV
                     IKGKISVGQLITFNTLLSYFTDPL"
     PFAM_domain     15286..15735
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_182_0011"
                     /evalue="1.80E-32"
                     /label="ctg13_182"
                     /locus_tag="ctg13_182"
                     /protein_end="410"
                     /protein_start="260"
                     /score="112.8"
                     /tool="antismash"
                     /translation="LSDITITIKEKTKVALVGISGSGKTTLAKMIVNFYEPYQGTIRLN
                     GTDLKTLDKKVLRRHINYLPQQAYIFNGSILENLTLGIKETVSQEDILKACEIAEIRQD
                     IEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAPTLILDEATS"
     CDS             15949..17268
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 52.2; E-value:
                     7.3e-16)"
                     /gene_kind="transport"
                     /locus_tag="ctg13_183"
                     /transl_table=11
                     /translation="MNPNLFQGAEFYRRRYQNFATLLIYPLLLLVGFLGLFSLVAKKEI
                     SVSTIGEITPTSVIASIQSTSDNPLSSHHLEENKVVKKDDVLLNYSETMDESQKTVLET
                     QLASAKRQKIGLETLKASLKQGVNFFIDDGVDEFGYLNTYNSFMLKVKELEPKTTPSQP
                     YGNYPYPSQTPQQDQGIQVPQTPNLPSSQPDVATGIQEQPPQIPSQQAPQTAMTSFRSA
                     RGKLLTYHTPKSAIKEIHSRGKFILTENASQNGQSQIDILRTEYIQKTDDQLTTVTNQI
                     AELEGKLQQADVQVQNNTIKAPQDGIVHLLRHLSKTSIIPKGTEIAQILPDMSKTRKVT
                     ITYYVNSSDIATIKKGQTVRLRLDKVSNQDLVVIGKVRAINASSTETKEGNLFKVKAQA
                     KISETDSRILKYGMQGRVTSIIGKKTFFNYYKDKILNDIQ"
     PFAM_domain     16843..17184
                     /aSDomain="HlyD_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13437.8"
                     /description="HlyD family secretion protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_183_0012"
                     /evalue="1.10E-16"
                     /label="ctg13_183"
                     /locus_tag="ctg13_183"
                     /protein_end="412"
                     /protein_start="298"
                     /score="61.6"
                     /tool="antismash"
                     /translation="TIKAPQDGIVHLLRHLSKTSIIPKGTEIAQILPDMSKTRKVTITY
                     YVNSSDIATIKKGQTVRLRLDKVSNQDLVVIGKVRAINASSTETKEGNLFKVKAQAKIS
                     ETDSRILKYG"
     CDS             17417..17554
                     /locus_tag="ctg13_184"
                     /transl_table=11
                     /translation="MTHLKTSKQFKELSEKELAEIDGGKGKSIFKKILDIIHKTDYKAR
                     "
     PFAM_domain     17426..17494
                     /aSDomain="ComC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03047.16"
                     /description="COMC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_184_0013"
                     /evalue="8.40E-05"
                     /label="ctg13_184"
                     /locus_tag="ctg13_184"
                     /protein_end="26"
                     /protein_start="3"
                     /score="22.3"
                     /tool="antismash"
                     /translation="LKTSKQFKELSEKELAEIDGGKG"
     aSDomain        17444..17488
                     /aSDomain="TIGR01847"
                     /aSTool="tigrfam"
                     /description="bacteriocin_sig: bacteriocin-type signal
                     sequence"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg13_184_0003"
                     /evalue="4.20E-05"
                     /identifier="TIGR01847"
                     /label="ctg13_184"
                     /locus_tag="ctg13_184"
                     /protein_end="24"
                     /protein_start="9"
                     /score="21.8"
                     /tool="antismash"
                     /translation="FKELSEKELAEIDGG"
     aSDomain        17444..17497
                     /aSDomain="TIGR03949"
                     /aSTool="tigrfam"
                     /description="bact_IIb_cerein: class IIb bacteriocin,
                     lactobin A/cerein 7B family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg13_184_0004"
                     /evalue="1.70E-05"
                     /identifier="TIGR03949"
                     /label="ctg13_184"
                     /locus_tag="ctg13_184"
                     /protein_end="27"
                     /protein_start="9"
                     /score="22.5"
                     /tool="antismash"
                     /translation="FKELSEKELAEIDGGKGK"
     CDS             complement(17632..18966)
                     /locus_tag="ctg13_185"
                     /transl_table=11
                     /translation="VTDLVQFLVQFIDTLCFVFLFAFTQDKKITLWQCLLIALGKYIIF
                     SLLFLFLPNFFFELVTPFYFLSVSFLLNRKLEGCLQIFRGLFPITLHHIIYLGLVYFII
                     PLAKMGYEDVNRSVIISISLSISSTIISYCFLKYFNYYFKTEYFAKLNAQERRFLIIIN
                     VSMILYYILIKYVVQSVGIDTDLYKASIVFIYIVFFLTMINRLDKSMQIELKEELMFQK
                     DIQLQNLKEYSKQIEDLYIDIKRFRHDYLNILKTLAIGIEEKNFTVIESIYQETIKDTD
                     KPFKNTKYDIGRLINVKNESLKSLLAVKLTQARENGVVTSIEIPTTIDVEDIEMIDCVT
                     IISILLDNAMEAALKSEKKILKLAFFETISQQIILVENTIKEERIEVKQLFELGFSSNG
                     YGRGIGLANVSSIIGKYSHIVLETKSQNYYFTQTIKIKKRVKRAM"
     PFAM_domain     complement(17659..17967)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_185_0014"
                     /evalue="3.70E-16"
                     /label="ctg13_185"
                     /locus_tag="ctg13_185"
                     /protein_end="436"
                     /protein_start="333"
                     /score="59.0"
                     /tool="antismash"
                     /translation="EMIDCVTIISILLDNAMEAALKSEKKILKLAFFETISQQIILVEN
                     TIKEERIEVKQLFELGFSSNGYGRGIGLANVSSIIGKYSHIVLETKSQNYYFTQTIKI"
     CDS             complement(18963..19706)
                     /locus_tag="ctg13_186"
                     /transl_table=11
                     /translation="VNIYILEDNLFQKSYLEFLIEDILRENQFKSSAIFSFDNPDKLIQ
                     AIAGKGQKQIFLLDIEIHQVEQAGLQLAQRIREQDPLATIVFITTHTEMMPLVFQLQIG
                     VMDYLDKDLSKEALKQRLTSLLDKINESSELVDLKDYFIYETEYTEVQLPFAKINYIET
                     SPRPHKLILHTNTDRIEFTGKLQEILQKEKRFIKCHRSYVVNPKNISKINTKERVAYFS
                     DGSSCIISRTMVKELKRIVKEGREV"
     PFAM_domain     complement(18984..19253)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_186_0016"
                     /evalue="6.50E-21"
                     /label="ctg13_186"
                     /locus_tag="ctg13_186"
                     /protein_end="241"
                     /protein_start="151"
                     /score="74.5"
                     /tool="antismash"
                     /translation="QLPFAKINYIETSPRPHKLILHTNTDRIEFTGKLQEILQKEKRFI
                     KCHRSYVVNPKNISKINTKERVAYFSDGSSCIISRTMVKELKRIV"
     PFAM_domain     complement(19341..19655)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_186_0015"
                     /evalue="6.20E-13"
                     /label="ctg13_186"
                     /locus_tag="ctg13_186"
                     /protein_end="122"
                     /protein_start="17"
                     /score="49.0"
                     /tool="antismash"
                     /translation="FLIEDILRENQFKSSAIFSFDNPDKLIQAIAGKGQKQIFLLDIEI
                     HQVEQAGLQLAQRIREQDPLATIVFITTHTEMMPLVFQLQIGVMDYLDKDLSKEALKQR
                     L"
ORIGIN
        1 gaatggcttc caatacttct tcatggggca ttgagccaat cggtaaatgc aacatgaaac
       61 ggttaagtcc aagtgcttca atcaatccga tgatttttgt ggcaacatgc tctggatctc
      121 cgacaaacat tgccccgtct ggtcctactt gttgcaagta agtctcataa gtcatcgatg
      181 accagtgagg acgatccttc ccaatattat ctgtttcagt cttggttggg tagtaataat
      241 tgtcaatagc tgattggtta ctcttttcca gccaccccca tgaatgtgct gcaactttca
      301 ttttgctcaa atcatgacca tgtcgactcg caatttcacg ataaatagcg actaactgtc
      361 caaaggcctt gggattgcca ccgattgtcg cataggcgat aggtaaacca cgctccgcaa
      421 ttttaaccgt tgaatccaag tttccacctg tcgccaccca aattggaaag tcttcttgga
      481 tagctcttgg atagacaggt cttttttcca ccgtttgggt atgtttgcct gcccagctta
      541 gttctgtatt atcacgtatc ttaatgagca tatccaattt ctcatcaaat agctcatcgt
      601 aatcccgtaa atcgtagcca aagagtggga aggattcgat aaatgagcca cgaccagcca
      661 tgatttctgc acgaccgttt gatagggcgt caatagtcgc aaactgttgg taaacacgaa
      721 caggatcatt agaagataaa atagtcaccg cgctcgagag acgaatacgc ttggtattaa
      781 ctgctcctgc tgctaaaata atctccggtg cagacaccgc aaaatcttcg cgatggtgtt
      841 cgccaatagc ataaatatcc aaacctacct tgtcagccaa ctcaatttcc tccaccaggt
      901 tgcgaatacg ttgcccgtgg cttaaaagct cacctgtttt ttccaaagga gttgtctcgc
      961 caaaagttgt aattcccagt tcaatagtca tttataatac ctcaattctt tatcttgaaa
     1021 atattttatt actaactagt tatattatca agaaaagcgt cttgagataa aaaagagtgt
     1081 tagccctcac caataacgtc atctacttta ccgccgagct ttatcggaaa attcacgaca
     1141 cttctaacag atttgaaatt ttaaaaagag ataatgctca aaaaaatata cactaaaaga
     1201 ccactcggat gagaccagag tggatgcacc aatgagaata atcaagaata aaaacatcca
     1261 ctggctttac ttcaagtaat agcaagacag aattatgtct ttttttaaac gtcagatttt
     1321 tcttgatttg atagataaga aaagaagatt ctcagattga ggaagaacag gattagctcc
     1381 ataaacagga ttcgtaataa actttatcac caactttgtc cacaacaata gctcaaaatt
     1441 aaagtgataa ggcaattaac ccctgtaaca cttatcttgt ctttcattcg gtatgacgat
     1501 attcctattt cattcaagag atttttttct tccaatcgct tatagtcatc ttgtgatact
     1561 tatgtctctt atcttagtaa gcctgctaac gattgagcca acatctgtaa tggcgctaga
     1621 tgaccacgct caacactagg atatttggcc aaccataatc ctaagtcaat aaccgacttg
     1681 ggagcctcat aacgatgaca aacgagataa taagaaatag attggctaag ccgtgctgta
     1741 attgccgaaa catcacgatt cgttttggca ttctccaact cagccataca attctcaaat
     1801 aataaattta agtcaccatt tctttgcaca tgataatcgt ttagcacctt catcaattca
     1861 tttttcaatt ctgcttttaa tttcttagac attagtttcc tctccttcaa cgagttggta
     1921 ttccttttga aacgtttttt cagaaatgac acgatgattg gtgacatcaa gatagtcacc
     1981 tggataggct aagacataca tcccgtagcc accaaatccg cctgccatcg caccaacggc
     2041 gcctgtttta gcattttcaa ttgctgatgg ttgtaaagca gccatcaaaa tcctcacatg
     2101 atgatcaatc caaaccataa tgtttttatc aaaagcttct tgaacccagt ctggataagg
     2161 ttcaattcga ttaactttcc aaaccaaaac aggttcattt ctatataaaa tcgccacctg
     2221 aaatctccta aaattattta ccaagccccc ataaacctat gctcatcaat cccttggcga
     2281 tatttgaata tttttcacca cgataggcaa tctcccgata aagccttgca acatttggag
     2341 ataatttttt atagtcttta agatttttca ctgccagctg tcgcaaatcc tccgcaaacc
     2401 gcatcacact aacttgatag tcactaccac gctccaaatc agacataaaa gcccgtaaaa
     2461 tgtctctttc ttcttgactg actgatgggt ctaaaatcag attataaacc ctaatcaaca
     2521 tttgttctct atcattagtc attgacttat ctcctataca ctaattttct cttgttcaat
     2581 aagtatacca ccaataagta gtattttctt ttaaaatcct aaacagtcat ttaactttcc
     2641 tgaatggtaa aaatccaaga ctcatctgct gacaagtctt ggaaaattct taattccagt
     2701 aagagaaaaa ctagatagta attacaaagt gttctacact ggaaaagaaa taggggaatt
     2761 gatggctaaa aaatacgcca acaatctaca ggtgacctca aacaacaaat ggttgaactt
     2821 cagaatacag gaaaaagcgt agtgagctta tcaagaaata tgatttaaca ccctaaacct
     2881 ttgataagtg gggtaaatag gcaaaaccca ctgattcata caaaaccatt gatgagctaa
     2941 cggatgaaca gcgtgagctg attgtccttg ggaagcgtaa taaagagcta gaaagataac
     3001 gaaagtctcg aagccaaggg aatcaccgta tcccgtcgtc gaatcataaa tagacactga
     3061 acttagtttg tatctatcaa cagtctgatt caaaacgcat tctaaaggga aaaatgaggc
     3121 gctaattcca aatcatttag ctagactatt ttacgaacaa gagcctttga atactattgt
     3181 gacagaatta acctatgtct gattcattat caacctcttc aatcgtgaaa tcattgacgt
     3241 atccgttgtt tagcgtaaga cctctgcgtt ggtgaaataa gctattcaga tcctcccctt
     3301 acgccttaac caagactaac tccactctga ttgcggaaaa gaattcgata atcgaatgat
     3361 tgatgacttc atagaagtct ttgacatcac tcgttcactt tatcaagccg gctgccctta
     3421 tgacaatgcc gtctctgaga gtaattacca ttcttttaag attgagttta tcaagcaaga
     3481 gaccttccat actctggaag aatcaatctt aaaaccgagg aatatgttca ctggtggaac
     3541 ctccaccgca ccgtattcac agcagttctt agctattaaa caccaatgac taagagatta
     3601 atcgcttaag aaaaaacact ttataacatt tgtacagaaa aagcgttgcc ttttcattta
     3661 gaccatctat tcacaatgga tgataatgac ggttgtcgta aattttaatt ggtgaataca
     3721 tatatgatat acggaatact gataaaagta ttaacggcaa catgagcaac cattgataac
     3781 tttaaattcc ttgaataatg gtaaatcatc gcaaatccta aaccataaac aaagtaaata
     3841 aaaaatgcga tggttgacca aggatattta tagatatgaa tcattgagaa taagcatgct
     3901 gaaataagaa tatcaattcc atacgtgctt ttcctgaata atgcattcat taacaatcct
     3961 cgataaatca attcttcaac aattggacct agcagacaga ttaataataa aaataaatag
     4021 gagtaatatt ttccggtact gtagtaaaga aaatcattaa tcgcttgaga attagctgta
     4081 ctattagtta aatgttttat tagaaaatat tcaacgctat atataccaag taaactgatg
     4141 catagaattc ttatattttc tagagtgagt agtttgttct gatacaattc ctcgttattg
     4201 acttgtttaa ataataaata ggctaatatt attgtcactg tatccaacaa aacataatat
     4261 agataatata agtccgaata aaaaccataa aatggaaata aaatatccaa acatttagga
     4321 attgataaat gaaaaaacat tattagcccc atagctataa tgttaaaaag actcttatct
     4381 tttttcattc tatttattcc acggtgccga tgaaatatct ctaggaaata tcatataatc
     4441 ataccaaggt acttgaattc caccttcaac acttgaaagc accatctcat ccatcatttc
     4501 aaactgttca actatttttg tattcatttt gaacacctcc tatttttatt tcgtatcgcg
     4561 actacgattt tattatagca atcatttttt taaataaatg tctaaatcct aaacagtcgt
     4621 ttaactttcc tgaatggtaa aaaggtcatt aatttaaagg aaaagcggtt aaatctacaa
     4681 tttattgtat aaaaagagca gataaaacgt tagatatgag gcaaatattt gtcccttact
     4741 cattattctc ctaaacgaac cactatccaa aaacaggagt gcatatcaaa aatcaagaag
     4801 atcccgctac tgtcttcttg attttaatga tttaaaactc attatctaaa aaaatgataa
     4861 gctatctcag atagtaattg gatgagaaaa aaaaatagta gcgattagca tatatttttt
     4921 gaaaagattt tttgattttc tggatattac atacataatt ggagtcaata ttaaataagg
     4981 taacaaaaat ttaacaataa tcatttaaat agtccatctg aaatctcttg tgcaccagct
     5041 ataaaacatc caactcctgc acttagtgcg cctcccgcag caccagatgc tatgccatct
     5101 attgccacca aaacaatatc agtaaaacaa gcacctgcgc tataacctcc gacagtattc
     5161 tcaaggttca aattagccat cacttctaat tgttcaattg tgttcttcat tattaatacc
     5221 tcctattttt atttcgtatc gcgactacga ttttattata gcaatcattt tttaaaataa
     5281 atgtctaaat cctaaacagt cgtttaactt tcctgaatgg taaaaaggtc attaatttaa
     5341 aggaaaagtg gttaaatcta caatttattg tataaaaaga gcagataaaa cgttagatat
     5401 gaggcaaata tttgtccctt actcattgtt ctcctaaacg aaccactatc caaaaacagg
     5461 agtgcatatc aaaaatcaag aagactactg cactgcctcc ttgactgtta tttattatgg
     5521 aagaatgtat aataactggc taaaagtgcc accattgtta tatttagtta atataatcat
     5581 ttttattcag ataaaaagta gtggacacca tttgttagta gttttaattg tgtcagtata
     5641 attaaaaaac gaaatttcaa caaatattaa aaacacctaa actatttatc agttaggtga
     5701 aaacatccta tttaagtaat gactagatta attaaatccc aatagacata tccattccat
     5761 aatatatgaa ctagtattgg acaatagata gttctagtaa aacgatacat cagggcatat
     5821 aaagttccag gtatggcata cacccagaat gcttggaaat tgccacttgg taatacgtga
     5881 ctagcactaa atactattgc agaaagcaaa acatcaaagt aatagggtga ctctttaaaa
     5941 taggtctcca ttaggagcat acgattaaat atttcttctc gtattggtcc taagatgaca
     6001 ttccaaagta taaaaccttg taaaaagaaa tttccattgc tgtaagataa gatggtgttc
     6061 agactattag tgttttcggt caatggtatt gaaaacaatc gagagctagt tagatcaaag
     6121 ataaatatag cgctacctaa gcaaaaagtt atcggagcat accaccattt tgccccgaat
     6181 atacgaaatg gcttagaatt aaatcttgta ctttgccata ggcaaattat taggatattc
     6241 agaaggagaa tagcatttac taataaatag aagttgtcat caaaattcct ttgtttccac
     6301 caatataact gtatctgagc taatatatta tggaagacaa tataaataaa gacgggaaat
     6361 aagtaaatgg atgttttttt tagcatagaa aaatatagtt attttaaaac ggcatcaacg
     6421 gaacttttag gtgatagtat taaaccataa tcgtgccaag gtaacatgac accaccattg
     6481 atatcaagca gtttctctgt tgcaatttct tcataaattt tcattttaat ttttctcctg
     6541 taatgttcaa tattgttgag gtatataaat gatatatgcc aaataagcga cggtttaaca
     6601 gtactgataa aaattaacta gctagttgaa aggcagtact ttttgtacag aattcataaa
     6661 ttattaatgt gttatcagtc taagagctat gaatgtttgg taattgaagc ttccaatgta
     6721 caagccctat aaattctgtc gtgaaatttt ttaaaggaaa tcctgaccaa aatatagata
     6781 aaaaagacgg tcaatataac catttgaggt atgatagttt ccatgacgtc ctccacttag
     6841 gactttataa agactgatta agaagattgg cttcgtttat agatatatta gctatttttt
     6901 caatcttttt tatcaaaata aacgagtaaa gaggctaata aagtaacaat tgataacata
     6961 tttgtcgttt gttttgataa cgatagttga taanaaacta anaagaataa gtacggtgtt
     7021 agatgagtta cactttttct ataaatagca tgaatagtcg taaaaacaat tatagaagat
     7081 gataaaacta taaaaactgt gtaaatcatt taattaacct tatatgccag ataggcacta
     7141 cctgctgtaa cgccaacaac acaaactccc tttaaaacag gatgaggaat tttacaatat
     7201 tttatacctg cactaagacc tgaaagtcca ccaattgcag catttccagt agggttacca
     7261 ccacttatat tggcaatatc atttgttgct aattctttat attttttctt cattatactc
     7321 ctctctaaaa tccacctgtt gcccctgttg ctactgtcca taaagtaata ctcgctttag
     7381 ccccaatata gacacaagct aatccacaaa ttggaaaaac actatagtag ctctggcact
     7441 acttgaaacc aaggcacccg agacattaac ttgccaatta tttttactac cttcaatacc
     7501 tgaaagcacc atttcattca tcactttaaa ttgtcaactc ttatttaaac aaaaaccaag
     7561 aagactcatt aaaggtcctc ttgattttca gtagttttct acttatacca gtcaaactag
     7621 ttaatgtagt tttgttccta ccctacttaa ctgatataac ctcttcgatt cggatataaa
     7681 aagaatataa cactatttgt taatagcatt gccattggta ttgtatcctc ttttaaaata
     7741 aagaggggga caactactag aactgaggca acgacaacta gaagagcgat tttcatttgt
     7801 tgttttaaaa aaacatagtt tactttataa cgttttaaca tggcataagc ccataaaaca
     7861 accaatacat gtaatattgt caataacaag aaataaactg tcaaatgact ctcttcgaca
     7921 cgaattgttc taaagaataa ataaaagact gtcaagtcaa tggtcaaaca caataaaaat
     7981 ccaaactgaa gaagacgttt tagtttatcc atgttgcctc caataagata atagttttta
     8041 tcacttggtg aatctatctt caaactgata cagtaccatc aaaggaataa gaagagctaa
     8101 aaaatcaaac caatttgaac ccttggtcac ataagaaacc attcctgcaa ttataaaaat
     8161 gaaggtacaa gccctataaa tcttgccgtg aaattttttt aacgaaatac taattaaaat
     8221 atagagcaga aagacgatta agataaccat ctgagttatg atagtgccca taatttctcc
     8281 tacttacaat tttggaggac gtaatccata tgcaacaact cccccaacaa cagcacctcc
     8341 tgctgcacaa attaagtaag cttgaggacc tgctaaaata cactgttgtc cagcttggaa
     8401 agctcctgct agagcaccag ttacgagtgc ccacctagtc caccaccaca aacatctgac
     8461 aaatcactaa ctgaaagttc attaaaaaag tttttatcca ttatatatct cctatttaat
     8521 gatattatct gcaataaatg ctatagaacc acctattttt gcacctgccc aagcacaccc
     8581 agcagtcgca gctaaggtag cccctgctgt catcatacct gcagctgtac ataagcttac
     8641 accaattcct gctccgtata cagctccagt agctgcatta ttccatttat ttgctccacc
     8701 atttacattg gatagacttt ctaattgtat ttcttgaaaa cttattattg attttgaatt
     8761 catattaatt tttcctcttt tattattgtg tgtcgcgacc acgtttttat tgtaactcac
     8821 atttggttat ttttatatta aaatcctgaa tggtcattga attgtcctaa atgggaaaat
     8881 tctaccgttc gagaaggagc ctgataataa aatcaattgc atagtaaatt aaactaacaa
     8941 ccaattttat atttacccca cactatcaat aattgagtga ctaataaaat tgagataact
     9001 tatttaggtg taattttctg acaaattttc ttataaatga tgagattaac taagtagata
     9061 aggaggaata gcccccaatg tatgaaacta tatataccaa aagtttctct aatataataa
     9121 attaaaggtg ccgaaactag tatttgtata gcaattataa gtattttttt cataaatact
     9181 tccctcaata acacctaatt actggagctg gattccaggc agaaggataa ctacaagtag
     9241 gtggtttaac tggccccttg ctaccacttt ttatcccctc tccaatcaca caaaaaatat
     9301 caaatactga acaaactttc ccaccgacaa tagtttctaa ttctgctgat tgtaattctg
     9361 cctgtctcat tttacttatt cctccctatt atttaatatt aatacagtgc cattgtttag
     9421 gatttttccg acagctagcc gtagcttcat tagcatagta tgaataaacc ccacctacca
     9481 agaaccataa taaagatgct cctccatcac caccttctac agtagcaaga tcagcagagt
     9541 tcaaatcgtt aaatttttcc attgcttttg tattcatttt gaatacctcc tatttttatt
     9601 ttgtgtagca accatatgtt tattataact ctcatttgtt tattttttca ttaaaatcct
     9661 aaacggtcac cgaaacgtcc taaatggtaa aaatatcaaa aatcctagtc accaatgtaa
     9721 gctggtgacc aggattcgta tgtcttagtt taagtgaaag gtgttgtaat agacttgtct
     9781 tttcaatatt aattcttacg caaatacaat tacgaagagc accactacta aattttgcaa
     9841 agaatgtatg ataataggaa acctaacatc atcgctagat ttgtagatta tgccatatat
     9901 tatggaactg atgaattgcg aattaattat tgcaccatag ccatggatat atgaaaatac
     9961 tatcgaagtg attatgatac ttatccaact tgaataacgt gctaaccttt cttgaagtat
    10021 ccctcgaaat aaaagttcct ctaaaatagg ttgagaaata atagttgtaa acatatacaa
    10081 tataaatatt actggcttgt tggacatttc agaaatttct tttggcacaa ctcctacact
    10141 gtaaccatta ccaataaaca aaagaatcaa atagattaat gttataagaa gtattactac
    10201 gatatatgcc aataaacgtt tatcattgaa cagccttctt ttagactgag gtttactcaa
    10261 atttatccct aaacattttg ctaaaagtct cagaaaataa agggagagga taatagctcc
    10321 aatacacgtc ataactctta gtatatcccc ttgagtatct tgcttaaagt tgacatggtc
    10381 tttggataaa gtagaaataa caggtgtttg gataaacata atcatgacca taaagaatat
    10441 aatagacaga gccaatctga aacacttctt aaatacacca atcattctat tttccccttt
    10501 ttaacattta cctttatact ttttaccgtt cacaccatca ataaatgaac aagtccctgc
    10561 aaaaagttta ttaacaactt taatgacatc agcaccaaga ttgataacag gagcgcctcc
    10621 taggattttt tcaagttctt tgtgactaag ttctttttgt gacatgtttc tttctccttt
    10681 aatacttact ataaataatt tctaaaatat cgtattgttt tagcaccatg gtgcacgatc
    10741 acaaatgaat ttaccagttt tgtttactgt atctcttaca gctctcccta atttatacat
    10801 acctctagta aaatcatcac cgcctgtaat gttttctaaa gtatcgccac ttaattctgg
    10861 aaactgtttg tatacttttg tattcatttt gaataccacc tattttttat ttcgtatcgc
    10921 gactacgatt ttattatagc aatcattttt taaaataaat gtctaaatcc taaacagtca
    10981 tttaactttc ctgaatggta aaaatccaag actcatatgc tgacaagtct tggaaaattc
    11041 ttaattctag taagagaaaa actaataaga atactaaaat agtaattaat tgattataga
    11101 ataaaaatta tggacagaaa actggaggtg cagggttaga agcacttctt ggaaaacatt
    11161 tcggagctga tttagtaggt gagttactta tcaatccgat tattttttta gttgtcggcc
    11221 aaatccaaca gcttggatcc cctatagaac aaactttccc tccagaaatt attgctagtt
    11281 gatattcact aatttctttt gtctgtattg cactcatcat tttccctttc caatatattt
    11341 atagtaacaa actgagccga taatcgtaat tatcagtgta gataattctt tcaaccaaat
    11401 cgttaaagga tagatttccg aaacgatttc tataataagt actgaaaatc tatatattaa
    11461 aaatagaatt attaaagatt ttaaattatt cattcgtaac tgtacctgaa ggtggactaa
    11521 actttaaaac aaaaccattg ctttggattt tgttgacaac tttttgtgct atcttttccc
    11581 acgccatcaa aaatttttcc agcgacatag atcccaagcc ctttgataac tggtcccaga
    11641 ggtaaggctc caccttcaac aactgaaaga ctctcaacat ttaaaacttc aaactgttca
    11701 actatttttg tattcatttt gaacacctcc tatttttatt tcgtatcgcg actacgattt
    11761 tattgtaact cacttttagt tattttttta ctcaaatcct aaacagtcgt ttttttgttg
    11821 cgaacggtcg ttttttacca ttcactactc attttttacc gtttaagata ataatgagac
    11881 catttaagaa cagttcgttt cttatcataa gacaatctgt ttttccattt acaactttgg
    11941 aaaatcttga caagaaaatt atcttcttcc acagccgtgt catccacttt tcaatctttt
    12001 ttatcaaaat aaacgagtaa agaggctaat aaagtaacaa ttgataacat atttgtcgtt
    12061 tgttttgata acgatagttg ataaaaaact aaaaagaata agtacggtgt tagatgagtt
    12121 acactttttc tataaatagc atgaatagtc gtaaaaacaa ttatagaaga tgataaaact
    12181 ataaaaactg tgtaaatcat ttaattaacc ttatatgcca aataggcact acctgctgta
    12241 acgccaacag cacaaactcc ctttaaaaca ggatgaggaa ttttacaata tttcgtacct
    12301 gcactaagac ctgaaagtcc accaattgca gcatttccag tagggttacc accacttata
    12361 ttggcaatat catttgttgc taattcttta tattttttca tcagtatacc ctctctaaaa
    12421 tccacctgtt gcccctgttg ctattgtcca taaagtaata cccgctttag caccaatata
    12481 atcacaagct attccacaaa ttggaaaaac actatagcag ctcctacact acctgaaacc
    12541 aaggcaccaa agacattagc ttaccagtta ttgttactat cttcaatacc taaaagcatt
    12601 ttagctatgc gtccttggtt gaacattccc cgtgccagct actactctca atatccataa
    12661 cgaatgtgcg ataaagtcct tattttcttt aaaatatcag cctgactctt tgtcaaagaa
    12721 atattgtttt cacttattat ttttgagatt gatacattta atcgacttaa gataaaaggg
    12781 acagatgatt tttcttcatc caattccttt ttataggata caagtaattg ttctaattgc
    12841 ttagtattag gactgttttt taaatctaaa attaaatcct gaattaattc tgaagcctta
    12901 tcttttcgct ccttcccacc tgaaaaccat ttaacgatac tcaaatttac atcctccatt
    12961 atagtttact ttattttcaa agttctttta ttattctatt tggtaacctt ttatataaaa
    13021 caatagaaag agtgcttaga aattttcatt ctcaagtacc ttttttaaaa tttgttccaa
    13081 aggcattagc tattgtatta accgatacca cccgaatgcc aacctgcatt tccacctgtt
    13141 aatccattca taactgaatt attagcaata gttccaaaga ctaaacgttt attcattttc
    13201 ctgacttgaa gcactagaaa aactttctga atattatttt tattttttct tcatcaaaaa
    13261 tctatctaac gctggtaata aaaaaccaat tattaatcct ataaaaaaac ttttaaaatc
    13321 catgcatcac caccaacaag ttgctccata tccgacacca ccaatgattg ctccgcctgc
    13381 agctcctcca atggctcctt gccaagttcc agtttttata cccattctca aaccatttcc
    13441 tgcaccagtg ccaatcgctg ctttaccaag tccactccat gtgcatttac caccttcaat
    13501 acttgaaagt accatctcat ccatcattgt aaactgttct agtgtatttg tattcatttt
    13561 gaatacctcc tattttttat tttgtgtcgc gaccacgttt ttattgtaac tcacttttag
    13621 ttattttttt actcaaatcc taaacagtcg tttttttgtt gcgaacggtc attttttacc
    13681 attcactact cattttttac cgtttaagat ttttttatct tcatgactta ctttttgata
    13741 gtattaaaaa ggcatatcat aaattaaagt cattagagga ggaattaatg tccaaataca
    13801 aacgtacgtt catcccccaa gtagatgcta gagactgcgg agtggcagct ttagcttcta
    13861 ttgctgcctt ttatgggtct agatattccc tagcacactt gagagaacta gcgaaaacta
    13921 ataaagaagg aacgactgct cttggtttga tcaaagctgc tcaagagatt ggttttgaga
    13981 cacgtgctat tcaagctgac gccagccttt ttgacatgac agatgtcccc tatcctttca
    14041 tcgctcatgt caataaagaa ggtaaacttc aacactacta tgtcgtctat caaacgacca
    14101 aaaagggact catcattggt gaccctgacc cgagtgtcaa ggtcactaaa atgtcctacg
    14161 acacctttct ttctgaatgg acaggtgtag cgcttttcat ggcgcctaag ccatcttatc
    14221 aaccgcacaa agataaaaag aatgggctag ctagttttct tccactcatc tttaagcaaa
    14281 aagcagtgat tgcccaaatt gtcattgcta gcctactggt taccgtcatt aatattgtcg
    14341 gttcttacta cctgcaatct atcctagatg attacatccc caatcacatg ctatccacgc
    14401 tgggcattat ttctgttgga ttgattatca cctacatcat ccaacaaatc atgacctttg
    14461 ccagagacta cctcctcact gtgctcagtc agcgtttgac gattgatgtc attttatctt
    14521 atatcaagca catctttaac ttgcccatgt cttttttttg cgactagacg cactggggaa
    14581 attatctcac gttttactga tgccaatgcc attatcgatg cactagcttc aactattctt
    14641 tcccttttcc tagatttctc tatcgtcatc atcgtcggaa gtgtcttgtt acttcaaaac
    14701 cccaaccttt tctttctctc cttagtttcc attcccattt atttggtgat tatttttgcc
    14761 tttatgaaac cttttgaacg catgaataac gatgtcatgc aaagcaactc catggttagt
    14821 tcagccatta ttgaggatat taatgggatt gaaacgatta agtcattaac tagcgaagaa
    14881 attcgttatc aaaagattga ccgtgaattt gtcgattact tagacaaatc ctttacctta
    14941 agcaaactgt caacccttca atcagccttg aagcaaggcg ctcaactcct tctaaacgtc
    15001 ctcattctct ggttgggatc agaccttgtc attaaaggaa agatttccgt cggtcagctc
    15061 atcaccttta ataccctgtt aagttatttc actgaccccc ttgaaaatat catcaacttg
    15121 caaaccaagt tgcaatctgc caaagttgcc aacacacgtc tcaatgaagt ctacttggtt
    15181 gattccgaat ttaaagacca gacctttgag accgatcctg ccacacttaa aggggatatt
    15241 gtttttgatc aggtctctta taaatatggt tttggacgag acaccctgtc tgatattacc
    15301 atcaccatca aggaaaaaac aaaagttgct ctcgtaggta ttagtggctc aggcaaaaca
    15361 actcttgcca agatgattgt caatttttac gaaccttatc aagggactat tcgtttgaat
    15421 ggcacggatc ttaaaacgtt ggataagaaa gtgctacgac gtcatatcaa ctacttgcct
    15481 caacaagcct atatttttaa tggctctatt cttgaaaacc tcaccctagg tatcaaagaa
    15541 accgttagcc aagaagacat cctgaaggct tgtgagattg cggaaatccg tcaagacatt
    15601 gagcagatgc ccatgggcta tcagaccgaa ctctcagatg gagccggcct atctggtggt
    15661 caaaagcagc gcattgctct agctcgtgcc ttgctcacaa aagcaccaac actcattctt
    15721 gatgaagcta ctagtgggtt agatgtctta actgagaaaa aggtaattga caacctctta
    15781 gcccttgata agaccattat ctttgtcgct caccgcttga gcatcgccca acgtgcggag
    15841 aaaattcttg ttctagagca aggaaaagtt gtcgaagaag gctcgcatag agacttagtc
    15901 agacgacaag ggttttatta tcatttattt agtaaataag gagaatttat gaatccgaat
    15961 ctttttcaag gtgctgaatt ttacagaaga cgctaccaaa attttgcgac cttactgatt
    16021 taccccttac tcctattagt tggcttctta ggactctttt ctttagtagc caagaaagaa
    16081 attagtgttt caacgattgg tgaaatcaca ccaaccagtg tcattgcctc gattcaatca
    16141 actagtgata atcccttatc aagtcatcac cttgaggaaa ataaggtcgt caaaaaagac
    16201 gatgtcctcc taaactattc tgagacgatg gatgaatctc agaaaacggt tctagaaact
    16261 caattagcca gtgctaaacg ccaaaaaatt ggtcttgaaa ctttgaaagc tagtttaaag
    16321 caaggggtta attttttcat tgatgatggc gtggatgaat ttggctattt gaatacttat
    16381 aacagtttta tgcttaaagt aaaggaattg gaacctaaaa cgacaccatc acaaccctat
    16441 gggaattatc cctaccctag ccaaacacca caacaagatc agggaattca agtccctcag
    16501 acgccaaatc tcccctctag tcagccagat gtcgcaacag gaatacagga acagccccct
    16561 caaatcccat cacaacaagc accgcaaacg gctatgactt cttttagatc tgcaagagga
    16621 aagttattaa cgtatcacac gcctaaaagt gcaattaaag aaatccacag ccgaggtaag
    16681 tttattttga cagagaatgc ctcacagaac ggtcaatcac aaattgatat tctccgaacg
    16741 gagtacatcc aaaaaacgga tgaccagttg acaactgtta ccaatcaaat cgcggagctt
    16801 gagggaaaac tccaacaagc agatgttcaa gttcaaaata acacgattaa agcgccacaa
    16861 gacggtattg ttcacctctt aagacatcta tctaaaacga gcatcattcc aaaagggact
    16921 gagattgcgc agatccttcc tgatatgagt aagacgagga aagtcactat tacttactac
    16981 gtcaattcca gtgacattgc gacaattaaa aaaggacaaa ctgtccgtct cagattagat
    17041 aaagtcagca atcaagattt ggtggttatt ggtaaagtca gagctatcaa cgcctcttca
    17101 actgaaacca aggagggaaa tctttttaaa gtcaaagcgc aagctaagat ttcagaaact
    17161 gatagccgta ttctgaaata tggcatgcag ggaagagtga caagcattat tgggaaaaaa
    17221 acattcttta attattacaa ggataagatt ttgaatgata tacaataaaa tcgatactac
    17281 ttacttaaat catatttaac ttgaatttct tagtttttta tccattcaga acaaaataac
    17341 aaccattcag gatttttggt tataaataga caaatctagt ttatacttaa cattattacg
    17401 aaaaggagaa gcaataatga ctcatttaaa aacgtctaaa caattcaagg agcttagcga
    17461 aaaagaatta gctgaaattg atggaggaaa aggtaagagt atctttaaaa aaattcttga
    17521 tattattcat aaaacagatt ataaagcacg ttagaaagtt gagaagctaa atcaattgaa
    17581 gaaaaaatag aaagcgatgt aaaaattggt catttcgtag aaatccgact tttacatcgc
    17641 tctctttact ctctttttta tttttattgt ttgagtaaaa tagtaatttt gtgattttgt
    17701 ttctaaaaca atatgtgaat attttccaat aattgaagaa acatttgcta gtccgatccc
    17761 tctaccgtat ccatttgaac taaagcctaa ttcaaagagc tgtttgactt caatcctctc
    17821 ttcctttatc gtgttttcaa ctaatattat ctgttgtgaa attgtttcga aaaaagctaa
    17881 ttttaatatt ttcttttcgg attttaaagc agcttccatt gcattatcta ataatattga
    17941 gattatcgta acacaatcaa tcatttcaat atcctctaca tcaattgtag taggaatttc
    18001 aatggacgtt actactccat tttccctagc ttgtgtcaac ttaacggcaa gcagactttt
    18061 taatgattca tttttaacat tgattaatcg tccaatgtca tacttggtat tcttgaatgg
    18121 tttatctgtg tcttttatcg tctcctgata aatggattca atgacagtaa aatttttctc
    18181 ttcaattccg atagctaacg tttttaagat attcaggtaa tcatgtctaa aacgtttaat
    18241 atcaatatac aaatcttcaa tttgcttact gtattctttt aaattttgaa gttgtatatc
    18301 cttttgaaac atcaactctt cttttaattc aatctgcatt gatttatcaa gacgattgat
    18361 catggtcaaa aagaaaacaa tataaataaa aacaattgaa gctttgtaga ggtcggtatc
    18421 aatgcctacg ctttgcacaa cgtattttat taatatatag tataaaatca tactaacatt
    18481 aataattatt aaaaagcgtc tctcttgtgc gtttaattta gcaaagtact ctgttttaaa
    18541 ataataatta aaatatttca aaaaacaata agagataatt gttgatgata tagaaaggga
    18601 gattgaaata atgacactcc gattaacatc ttcataaccc atcttagcta aggggataat
    18661 aaaatagacc aaaccaagat aaataatatg atgtagcgtt atcggaaaaa gtcccctaaa
    18721 tatctgtaaa caaccttcta attttctatt taataaaaaa gaaacactta aaaaataaaa
    18781 tggagtgacc aattcaaaaa agaaattcgg taaaaaaaga aatagtaatg aaaagattat
    18841 gtattttcct aaagcaatta gtaaacattg ccataatgta atttttttgt cctgtgtaaa
    18901 tgcaaaaaga aaaacaaaac acagtgtgtc aatgaactga actaaaaatt gaactaaatc
    18961 ggtcacacct ctctcccttc tttcactatt cttttcaact ctttgaccat tgttcttgaa
    19021 ataatacaag aactaccgtc actaaagtag gctactcttt ctttagtgtt gattttactg
    19081 atatttttcg gattgaccac ataagaccga tgacacttga tgaaacgttt ttctttttgt
    19141 aggatttctt gtaattttcc tgtaaattca atacggtctg tgttggtgtg gaggattaat
    19201 ttatgtggtc ttggggaggt ctcaatatag ttgatcttag caaagggaag ctgaacttcc
    19261 gtgtactccg tctcatagat aaagtagtct ttcaagtcta ctagctcgct gctctcgttt
    19321 attttatcca acaaggatgt caacctttgc ttcaaggctt cttttgaaag gtccttgtct
    19381 aaataatcca taacaccaat ttgcaactga aaaacaagtg gcatcatttc agtatgggtg
    19441 gtgataaaaa caatagttgc caagggatcc tgttctcgaa tacgttgtgc caactgtaaa
    19501 cccgcttgtt ctacttgatg gatttcaata tccaatagaa aaatttgttt ttgccccttg
    19561 ccagcaattg cctgaattaa cttatccgga ttatcaaaag aaaagatagc acttgatttg
    19621 aactggtttt cgcgaagaat atcttcaatc aaaaattcta agtaggactt ctggaaaaga
    19681 ttatcctcta atatataaat gttcaccgct tccccctatt catagtaact aataccagtt
    19741 ttgcttattt tcatctcaag gcgagattgg taactaattt cctaaattaa aatcaactaa
    19801 ttttatcttt ttttaaaaca ctcgtcaaaa tattttttac cacaacctca tctcattatt
    19861 aaaagcgtta actatttata atgtttaatt tctaagtttt gtgcaaatat ataattgtga
    19921 ctagtcgttt ttaatgaaat attaggatat ttatttataa tttgatgtgc attatatagt
    19981 cctactcctc ttccattacc tttgctactt accccaaact tatatatatc ctcaatattt
    20041 agtgattcat ttttcataga attttcaatg atgaatattt gtttatttcc ttcagaaaaa
    20101 aaggcaatat taattgatga tacggttgca tctaaagcag catctagagc attatcgcat
    20161 aaaatggaaa ctatcgtaat aaaatcaact aaatccattc ccttaggttc aattgcttct
    20221 ggaacctcca aactaatgga tacatttttt tcagtagctt gaataaattt ggcagcaagt
    20281 aaacttttta aggctgaatt ttttacattc gttaacctac caatatcata tttatgatct
    20341 ttcaatgttt tattagaatc cttgagaaca gattggtaaa cttcattaac cgcatcaata
    20401 tccttactct ctatccccaa cttcaaagtc gtcaaaagat tggcataatc atggcgaaaa
    20461 ctacgaactt ccttgtaaag ttcctcaatc cgcttgctat aagtttccat atcttttaat
    20521 tgtaactctc tttgtaaaat taaatctttt tggactctct cacgcaaacg tcgatcaagt
    20581 atatttataa ttcctataaa gagaatcaat aacaagataa ctaagaactt tctgtaggct
    20641 aatgtttcta atgatttttc aaattctaaa taggtaaata tttctatcaa aataaagtat
    20701 acaatcatta caatatttat gaaatttaat aactgttttt cgcctgaatc caaatttttt
    20761 cgttctaaaa tggtaaagtc atattttaac catctcaaaa ataaagtact caaaaaagca
    20821 gataagatat agaaaaatag ccagtacttt gtcgaatcaa gataatcgtt tgttaaacta
    20881 aaaactggca aaagaaaaaa agaaatagat ctataaaata aatttctcaa tgttatagg
//
