LOCUS       NZ_CP083737.1          25479 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP083737.1 Hafnia paralvei strain AVS0177 chromosome, complete
            genome.
ACCESSION   NZ_CP083737
VERSION     NZ_CP083737.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:09:59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3841926
            Orig. end    :: 3867405
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25479
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[3851926:3857405]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15479
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..25479
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..25479
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="4"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             complement(1177..2940)
                     /locus_tag="ctg1_3539"
                     /transl_table=11
                     /translation="MKAVRPGKLKRQEDQASFVSWRFALLCGCIFIALMGLLGRVAYLQ
                     VINPDRLVREGDARSLRTQPILTSRGMISDRAGRPLAVSVPVNAIWADPKEVNEHGGIT
                     LDTRWKALADALEMPLDKMAARINANPKGRFVYLARQVNPAMADYIHKLKLPGIFQKQE
                     SRRYYPAGQVTAHIIGVTNIDGQGIEGVEKSFDRWLTGQPGERTVRKDRFGRVIEDISS
                     VDSQAAHNLALSIDERLQALVYRELNNAVAFNKAESGTAVLVDVNTGEVLAMANSPSYN
                     PNNLADTPKEAMRNRAITDIFEPGSTVKPMVVMTALQHNVVKENSVLNTLPYFVNGHQI
                     KDVARYAELSITGILQKSSNVGVSKLALAMPSSALVETYSHFGLGKATNLGLVGESSGM
                     YPKKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSLGIYRPLSITKVDPPVPGERVF
                     PEPIVRTVVHMMESVALPGGGGTKAAIKGYRIAIKTGTAKKVGPDGRYVDKYIAYTAGV
                     APASNPRFALVVVINDPQAGKYYGGAVSAPIFGAIMGGVLRTMNVEPDALPTGDKNELA
                     NNKKEGSGGRS"
     PFAM_domain     complement(1282..2166)
                     /aSDomain="Transpeptidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00905.24"
                     /description="Penicillin binding protein transpeptidase
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3539_0068"
                     /evalue="1.80E-82"
                     /label="ctg1_3539"
                     /locus_tag="ctg1_3539"
                     /protein_end="553"
                     /protein_start="258"
                     /score="277.1"
                     /tool="antismash"
                     /translation="GTAVLVDVNTGEVLAMANSPSYNPNNLADTPKEAMRNRAITDIFE
                     PGSTVKPMVVMTALQHNVVKENSVLNTLPYFVNGHQIKDVARYAELSITGILQKSSNVG
                     VSKLALAMPSSALVETYSHFGLGKATNLGLVGESSGMYPKKQRWSDIERATFSFGYGLM
                     VTPLQLARVYATIGSLGIYRPLSITKVDPPVPGERVFPEPIVRTVVHMMESVALPGGGG
                     TKAAIKGYRIAIKTGTAKKVGPDGRYVDKYIAYTAGVAPASNPRFALVVVINDPQAGKY
                     YGGAVSAPIFGAIM"
     PFAM_domain     complement(2284..2736)
                     /aSDomain="PBP_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03717.17"
                     /description="Penicillin-binding Protein dimerisation
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3539_0067"
                     /evalue="5.50E-17"
                     /label="ctg1_3539"
                     /locus_tag="ctg1_3539"
                     /protein_end="219"
                     /protein_start="68"
                     /score="62.7"
                     /tool="antismash"
                     /translation="SRGMISDRAGRPLAVSVPVNAIWADPKEVNEHGGITLDTRWKALA
                     DALEMPLDKMAARINANPKGRFVYLARQVNPAMADYIHKLKLPGIFQKQESRRYYPAGQ
                     VTAHIIGVTNIDGQGIEGVEKSFDRWLTGQPGERTVRKDRFGRVIED"
     CDS             complement(3000..3320)
                     /locus_tag="ctg1_3540"
                     /transl_table=11
                     /translation="MIGNERHTLVAVIGGDILRHGKLPLILFIGVLVSAVLVVTTTHKT
                     RLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIATEKLQMQHVDPSQENIVV
                     KQ"
     PFAM_domain     complement(3009..3290)
                     /aSDomain="FtsL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04999.15"
                     /description="Cell division protein FtsL"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3540_0069"
                     /evalue="1.40E-36"
                     /label="ctg1_3540"
                     /locus_tag="ctg1_3540"
                     /protein_end="104"
                     /protein_start="10"
                     /score="124.4"
                     /tool="antismash"
                     /translation="AVIGGDILRHGKLPLILFIGVLVSAVLVVTTTHKTRLLTAQREQL
                     VLERDALDIEWRNLILEENALGDHSRVERIATEKLQMQHVDPSQENIVV"
     aSDomain        complement(3012..3260)
                     /aSDomain="TIGR02209"
                     /aSTool="tigrfam"
                     /description="ftsL_broad: cell division protein FtsL"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3540_0025"
                     /evalue="3.20E-29"
                     /identifier="TIGR02209"
                     /label="ctg1_3540"
                     /locus_tag="ctg1_3540"
                     /protein_end="103"
                     /protein_start="20"
                     /score="98.7"
                     /tool="antismash"
                     /translation="GKLPLILFIGVLVSAVLVVTTTHKTRLLTAQREQLVLERDALDIE
                     WRNLILEENALGDHSRVERIATEKLQMQHVDPSQENIV"
     CDS             complement(3317..4261)
                     /locus_tag="ctg1_3541"
                     /transl_table=11
                     /translation="MSEENYQHKTVLLDEAVNGLNLRSNGIYIDGTFGRGGHSRLILSQ
                     LGPEGRLLAIDRDPQAIAAAAEITDPRFSIIHGPFSDMATYVRELGLEGQINGVLLDLG
                     VSSPQLDDAERGFSFMRDGPLDMRMDPTRGLSAAEWLMKAEEEDIAWVLKTFGEERFAK
                     RIARAIVERNRLEPMTRTHELATLIANASPFREKHKHPATRSFQAIRIYINSELEEIER
                     ALNGALEILSPEGRLSVISFHSLEDRIVKQFIRHHSRGPQVPAGIPLTEAQLRSQGGRK
                     LKALGKMKPSSDEVSANPRARSSVLRFAERTVE"
     PFAM_domain     complement(3329..4246)
                     /aSDomain="Methyltransf_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01795.21"
                     /description="MraW methylase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3541_0070"
                     /evalue="4.70E-115"
                     /label="ctg1_3541"
                     /locus_tag="ctg1_3541"
                     /protein_end="311"
                     /protein_start="5"
                     /score="384.4"
                     /tool="antismash"
                     /translation="YQHKTVLLDEAVNGLNLRSNGIYIDGTFGRGGHSRLILSQLGPEG
                     RLLAIDRDPQAIAAAAEITDPRFSIIHGPFSDMATYVRELGLEGQINGVLLDLGVSSPQ
                     LDDAERGFSFMRDGPLDMRMDPTRGLSAAEWLMKAEEEDIAWVLKTFGEERFAKRIARA
                     IVERNRLEPMTRTHELATLIANASPFREKHKHPATRSFQAIRIYINSELEEIERALNGA
                     LEILSPEGRLSVISFHSLEDRIVKQFIRHHSRGPQVPAGIPLTEAQLRSQGGRKLKALG
                     KMKPSSDEVSANPRARSSVLRFAER"
     aSDomain        complement(3329..4252)
                     /aSDomain="TIGR00006"
                     /aSTool="tigrfam"
                     /description="TIGR00006: 16S rRNA
                     (cytosine(1402)-N(4))-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3541_0026"
                     /evalue="7.90E-124"
                     /identifier="TIGR00006"
                     /label="ctg1_3541"
                     /locus_tag="ctg1_3541"
                     /protein_end="311"
                     /protein_start="3"
                     /score="411.0"
                     /tool="antismash"
                     /translation="ENYQHKTVLLDEAVNGLNLRSNGIYIDGTFGRGGHSRLILSQLGP
                     EGRLLAIDRDPQAIAAAAEITDPRFSIIHGPFSDMATYVRELGLEGQINGVLLDLGVSS
                     PQLDDAERGFSFMRDGPLDMRMDPTRGLSAAEWLMKAEEEDIAWVLKTFGEERFAKRIA
                     RAIVERNRLEPMTRTHELATLIANASPFREKHKHPATRSFQAIRIYINSELEEIERALN
                     GALEILSPEGRLSVISFHSLEDRIVKQFIRHHSRGPQVPAGIPLTEAQLRSQGGRKLKA
                     LGKMKPSSDEVSANPRARSSVLRFAER"
     CDS             complement(4264..4722)
                     /locus_tag="ctg1_3542"
                     /transl_table=11
                     /translation="MFRGATTINLDGKGRLAVPMRYRELLLEESQGQMVCTIDLHQPCL
                     LLYTLPQWEVIEQKLSRLSSMNPVERRIQRLLLGHASECQMDSAGRLLIASTLRQHAGL
                     TKQVMLVGQFNKFELWDEENWYQQVKEDIDAQQTVTEPLSERLQDLSL"
     aSDomain        complement(4267..4722)
                     /aSDomain="TIGR00242"
                     /aSTool="tigrfam"
                     /description="TIGR00242: division/cell wall cluster
                     transcriptional repressor MraZ"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3542_0027"
                     /evalue="9.20E-61"
                     /identifier="TIGR00242"
                     /label="ctg1_3542"
                     /locus_tag="ctg1_3542"
                     /protein_end="152"
                     /protein_start="0"
                     /score="201.9"
                     /tool="antismash"
                     /translation="MFRGATTINLDGKGRLAVPMRYRELLLEESQGQMVCTIDLHQPCL
                     LLYTLPQWEVIEQKLSRLSSMNPVERRIQRLLLGHASECQMDSAGRLLIASTLRQHAGL
                     TKQVMLVGQFNKFELWDEENWYQQVKEDIDAQQTVTEPLSERLQDLSL"
     PFAM_domain     complement(4315..4494)
                     /aSDomain="MraZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02381.20"
                     /description="MraZ protein, putative antitoxin-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3542_0072"
                     /evalue="1.10E-20"
                     /label="ctg1_3542"
                     /locus_tag="ctg1_3542"
                     /protein_end="136"
                     /protein_start="76"
                     /score="73.5"
                     /tool="antismash"
                     /translation="LLGHASECQMDSAGRLLIASTLRQHAGLTKQVMLVGQFNKFELWD
                     EENWYQQVKEDIDAQ"
     PFAM_domain     complement(4498..4722)
                     /aSDomain="MraZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02381.20"
                     /description="MraZ protein, putative antitoxin-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3542_0071"
                     /evalue="3.70E-21"
                     /label="ctg1_3542"
                     /locus_tag="ctg1_3542"
                     /protein_end="75"
                     /protein_start="0"
                     /score="75.0"
                     /tool="antismash"
                     /translation="MFRGATTINLDGKGRLAVPMRYRELLLEESQGQMVCTIDLHQPCL
                     LLYTLPQWEVIEQKLSRLSSMNPVERRIQR"
     CDS             5602..6051
                     /locus_tag="ctg1_3543"
                     /transl_table=11
                     /translation="MFSPASRARSAAADIFALVVYSFIVGMLIEVFISGMSFNQSLSSR
                     LLSIPVNILIAWPYGVYRDWFIRQSQRCRSKGMAKILADLIAYVSFQSPVYAIILWYVG
                     ADGAQILAAVTSNAVVSMAMGVAYGYFLDYCRRLFKVSGYIKAQA"
     PFAM_domain     5614..6024
                     /aSDomain="AlaE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06610.15"
                     /description="L-alanine exporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3543_0073"
                     /evalue="2.30E-67"
                     /label="ctg1_3543"
                     /locus_tag="ctg1_3543"
                     /protein_end="141"
                     /protein_start="4"
                     /score="225.6"
                     /tool="antismash"
                     /translation="ASRARSAAADIFALVVYSFIVGMLIEVFISGMSFNQSLSSRLLSI
                     PVNILIAWPYGVYRDWFIRQSQRCRSKGMAKILADLIAYVSFQSPVYAIILWYVGADGA
                     QILAAVTSNAVVSMAMGVAYGYFLDYCRRLFKV"
     CDS             complement(6108..7112)
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 210.3; E-value: 7.4e-64)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3544"
                     /transl_table=11
                     /translation="VKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVREH
                     NYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPD
                     NEMRCIEHLLQRQVDAIIVSTALQPEHPFYQRWAKDPLPIIALDRALDPEHFISVVGAD
                     REDSEMLAEELRKFPAKSVLYLGALPELSVSFLREQGFRDAWREDPREVQYLYTNSYER
                     DAAGVAFSNWLKNNEMPQALFTTSFPLLQGVLDVTLKHHGHLPTDLAIATFGDNELLDF
                     LDCPVLSVGQRHRDIAERVLELVLASLDEPKKPKAGLSRMRRVLLKRGRLNRM"
     aSDomain        complement(6129..7109)
                     /aSDomain="TIGR02417"
                     /aSTool="tigrfam"
                     /description="fruct_sucro_rep: D-fructose-responsive
                     transcription factor"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3544_0028"
                     /evalue="6.00E-144"
                     /identifier="TIGR02417"
                     /label="ctg1_3544"
                     /locus_tag="ctg1_3544"
                     /protein_end="328"
                     /protein_start="1"
                     /score="477.2"
                     /tool="antismash"
                     /translation="KLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVREHN
                     YHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDN
                     EMRCIEHLLQRQVDAIIVSTALQPEHPFYQRWAKDPLPIIALDRALDPEHFISVVGADR
                     EDSEMLAEELRKFPAKSVLYLGALPELSVSFLREQGFRDAWREDPREVQYLYTNSYERD
                     AAGVAFSNWLKNNEMPQALFTTSFPLLQGVLDVTLKHHGHLPTDLAIATFGDNELLDFL
                     DCPVLSVGQRHRDIAERVLELVLASLDEPKKPKAGLSRMRRVLLKR"
     PFAM_domain     complement(6378..6929)
                     /aSDomain="Peripla_BP_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00532.23"
                     /description="Periplasmic binding proteins and sugar
                     binding domain of LacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3544_0075"
                     /evalue="1.10E-12"
                     /label="ctg1_3544"
                     /locus_tag="ctg1_3544"
                     /protein_end="245"
                     /protein_start="61"
                     /score="48.1"
                     /tool="antismash"
                     /translation="RSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDNE
                     MRCIEHLLQRQVDAIIVSTALQPEHPFYQRWAKDPLPIIALDRALDPEHFISVVGADRE
                     DSEMLAEELRKFPAKSVLYLGALPELSVSFLREQGFRDAWREDPREVQYLYTNSYERDA
                     AGVAFSNWLKNNEMPQALFTT"
     PFAM_domain     complement(6963..7109)
                     /aSDomain="LacI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00356.23"
                     /description="Bacterial regulatory proteins, lacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3544_0074"
                     /evalue="5.70E-19"
                     /label="ctg1_3544"
                     /locus_tag="ctg1_3544"
                     /protein_end="50"
                     /protein_start="1"
                     /score="67.7"
                     /tool="antismash"
                     /translation="KLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVREHN
                     YHPN"
     CDS             complement(7321..7812)
                     /locus_tag="ctg1_3545"
                     /transl_table=11
                     /translation="MRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSR
                     MTIQTVGDAKVLEQIEKQLHKLVDVLRVSELVQGSHVEREIMLVKLQASGYGREEVKRS
                     TDIFRGQIVDVTASLYTVQLVGTSDKLDAFLSAVREVAEIVEVARSGIVGVSRGDKIMR
                     "
     aSDomain        complement(7336..7812)
                     /aSDomain="TIGR00119"
                     /aSTool="tigrfam"
                     /description="acolac_sm: acetolactate synthase, small
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3545_0029"
                     /evalue="2.40E-66"
                     /identifier="TIGR00119"
                     /label="ctg1_3545"
                     /locus_tag="ctg1_3545"
                     /protein_end="159"
                     /protein_start="0"
                     /score="220.5"
                     /tool="antismash"
                     /translation="MRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSR
                     MTIQTVGDAKVLEQIEKQLHKLVDVLRVSELVQGSHVEREIMLVKLQASGYGREEVKRS
                     TDIFRGQIVDVTASLYTVQLVGTSDKLDAFLSAVREVAEIVEVARSGIVGVSRGD"
     PFAM_domain     complement(7339..7563)
                     /aSDomain="ALS_ss_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10369.11"
                     /description="Small subunit of acetolactate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3545_0077"
                     /evalue="2.30E-22"
                     /label="ctg1_3545"
                     /locus_tag="ctg1_3545"
                     /protein_end="158"
                     /protein_start="83"
                     /score="79.1"
                     /tool="antismash"
                     /translation="REIMLVKLQASGYGREEVKRSTDIFRGQIVDVTASLYTVQLVGTS
                     DKLDAFLSAVREVAEIVEVARSGIVGVSRG"
     PFAM_domain     complement(7609..7803)
                     /aSDomain="ACT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01842.27"
                     /description="ACT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3545_0076"
                     /evalue="8.10E-15"
                     /label="ctg1_3545"
                     /locus_tag="ctg1_3545"
                     /protein_end="68"
                     /protein_start="3"
                     /score="54.4"
                     /tool="antismash"
                     /translation="ILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTI
                     QTVGDAKVLEQIEKQLHKLV"
     CDS             complement(7815..9533)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 589.8;
                     E-value: 8.8e-179)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3546"
                     /transl_table=11
                     /translation="MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGCIEH
                     VLVRHEQGAVHMADGFARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVISGQVA
                     TSLIGNDAFQECDMVGISRPVVKHSFLVKHTEDIPTILKKAFYLASTGRPGPVVVDLPK
                     DIMSPAIKLPYSYPESVKMRSYNPTLQGHRGQIKRALQTLLAAKQPIIYAGGGVISSGC
                     HEELRELAERLNIPVTTSLMGLGGFPASHAQSLGMLGMHGTYEANMAMHNADVIFAVGV
                     RFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVDADIPIVGDAKEALATFLELLGQKEV
                     KQDFDGLRDWWQSIAQWRARKCLSYDTTSGRIKPQQVIETLHRLTKGEAYVASDVGQHQ
                     MFAALYYGFDKPRRWVNSGGLGTMGFGLPAALGIKLALPEETVICVTGDGSIQMNIQEL
                     STALQYDLPVVVINLNNRFLGMVKQWQDMIYAGRHSQSYMESLPDFVKLAEAYGHVGIS
                     IRTPDELESKLEQALAVKNRLVFVDVTIDETEHVYPMQIRGGSMDEMWLSKTERT"
     aSDomain        complement(7833..9524)
                     /aSDomain="TIGR00118"
                     /aSTool="tigrfam"
                     /description="acolac_lg: acetolactate synthase, large
                     subunit, biosynthetic type"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3546_0030"
                     /evalue="2.80E-280"
                     /identifier="TIGR00118"
                     /label="ctg1_3546"
                     /locus_tag="ctg1_3546"
                     /protein_end="567"
                     /protein_start="3"
                     /score="928.5"
                     /tool="antismash"
                     /translation="LSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGCIEHVLV
                     RHEQGAVHMADGFARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVISGQVATSL
                     IGNDAFQECDMVGISRPVVKHSFLVKHTEDIPTILKKAFYLASTGRPGPVVVDLPKDIM
                     SPAIKLPYSYPESVKMRSYNPTLQGHRGQIKRALQTLLAAKQPIIYAGGGVISSGCHEE
                     LRELAERLNIPVTTSLMGLGGFPASHAQSLGMLGMHGTYEANMAMHNADVIFAVGVRFD
                     DRTTNNLAKYCPNATVLHIDIDPTSISKTVDADIPIVGDAKEALATFLELLGQKEVKQD
                     FDGLRDWWQSIAQWRARKCLSYDTTSGRIKPQQVIETLHRLTKGEAYVASDVGQHQMFA
                     ALYYGFDKPRRWVNSGGLGTMGFGLPAALGIKLALPEETVICVTGDGSIQMNIQELSTA
                     LQYDLPVVVINLNNRFLGMVKQWQDMIYAGRHSQSYMESLPDFVKLAEAYGHVGISIRT
                     PDELESKLEQALAVKNRLVFVDVTIDETEHVYPMQIRGGSMDEMWLS"
     PFAM_domain     complement(7905..8354)
                     /aSDomain="TPP_enzyme_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02775.23"
                     /description="Thiamine pyrophosphate enzyme, C-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3546_0080"
                     /evalue="9.90E-50"
                     /label="ctg1_3546"
                     /locus_tag="ctg1_3546"
                     /protein_end="543"
                     /protein_start="393"
                     /score="168.4"
                     /tool="antismash"
                     /translation="DVGQHQMFAALYYGFDKPRRWVNSGGLGTMGFGLPAALGIKLALP
                     EETVICVTGDGSIQMNIQELSTALQYDLPVVVINLNNRFLGMVKQWQDMIYAGRHSQSY
                     MESLPDFVKLAEAYGHVGISIRTPDELESKLEQALAVKNRLVFVDV"
     PFAM_domain     complement(8547..8948)
                     /aSDomain="TPP_enzyme_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00205.24"
                     /description="Thiamine pyrophosphate enzyme, central
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3546_0079"
                     /evalue="3.30E-50"
                     /label="ctg1_3546"
                     /locus_tag="ctg1_3546"
                     /protein_end="329"
                     /protein_start="195"
                     /score="169.5"
                     /tool="antismash"
                     /translation="IKRALQTLLAAKQPIIYAGGGVISSGCHEELRELAERLNIPVTTS
                     LMGLGGFPASHAQSLGMLGMHGTYEANMAMHNADVIFAVGVRFDDRTTNNLAKYCPNAT
                     VLHIDIDPTSISKTVDADIPIVGDAKEALA"
     PFAM_domain     complement(9021..9521)
                     /aSDomain="TPP_enzyme_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02776.20"
                     /description="Thiamine pyrophosphate enzyme, N-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3546_0078"
                     /evalue="3.10E-57"
                     /label="ctg1_3546"
                     /locus_tag="ctg1_3546"
                     /protein_end="171"
                     /protein_start="4"
                     /score="193.0"
                     /tool="antismash"
                     /translation="SGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGCIEHVLVR
                     HEQGAVHMADGFARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVISGQVATSLI
                     GNDAFQECDMVGISRPVVKHSFLVKHTEDIPTILKKAFYLASTGRPGPVVVDLPKDIMS
                     PAIK"
     CDS             complement(10001..11803)
                     /NRPS_PKS="Domain: AMP-binding (14-468). E-value: 1.7e-89.
                     Score: 292.1. Matches aSDomain:
                     nrpspksdomains_ctg1_3547_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     275.7; E-value: 1e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3547"
                     /sec_met_domain="AMP-binding (E-value: 3.8e-89, bitscore:
                     297.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINELNKYHLVERIQQQIKHIPHRVALREWSAHGETPYTWQQVGL
                     RVEKLALALCALGVDVQERVAIFAHNSVSWSLIDLAILHLRAITVPVYSTNTAAQTAFV
                     LNDADVRILFVDGQSQYNAALALRGVCPQLEHIIVMSDSIDMQGCEIACTLDSFAASAQ
                     ERFLPLLKERIEQADMSDLFTLIYTSGTTGEPKGVMLNYTNMGAQLRLHDERLTVTAED
                     VSLCFLPLSHVFERAWSFYVMHSGAQNVYLSDTNQVREAMQSVKPTVMCAVPRFYEKIF
                     SAIHEKVAQAKWHKRAMFKCAIWVGEKRFLTERAGCKPNVVLSAMHKLADKLVLSKLRG
                     ILGGRVRFLPAAGAKMDDNVILFFQALGANIKYGYGMTETCATVSCWEENDFRFGSIGK
                     PLPDVEVRIGHENEIQVRGPIVMCGYYNKPLETAATFTEDGWLKTGDAGALDENGNLFI
                     TERLKDLMKTSNGKYIAPQMVEGTLAQDRFIEQVAVIADARKFVSALIVPCFESLEEYA
                     KSINLKYHDRLDLLRHSHIVEMFDQRLREMQKGLAKFEQVKRFTLLPEAFSMEQGELTP
                     TLKLRRKIINSRYQMEIESMYLEH"
     aSDomain        complement(10400..11761)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_3547_AMP-binding.1"
                     /evalue="1.70E-89"
                     /label="ctg1_3547_AMP-binding.1"
                     /locus_tag="ctg1_3547"
                     /protein_end="468"
                     /protein_start="14"
                     /score="292.1"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="QQQIKHIPHRVALREWSAHGETPYTWQQVGLRVEKLALALCALGV
                     DVQERVAIFAHNSVSWSLIDLAILHLRAITVPVYSTNTAAQTAFVLNDADVRILFVDGQ
                     SQYNAALALRGVCPQLEHIIVMSDSIDMQGCEIACTLDSFAASAQERFLPLLKERIEQA
                     DMSDLFTLIYTSGTTGEPKGVMLNYTNMGAQLRLHDERLTVTAEDVSLCFLPLSHVFER
                     AWSFYVMHSGAQNVYLSDTNQVREAMQSVKPTVMCAVPRFYEKIFSAIHEKVAQAKWHK
                     RAMFKCAIWVGEKRFLTERAGCKPNVVLSAMHKLADKLVLSKLRGILGGRVRFLPAAGA
                     KMDDNVILFFQALGANIKYGYGMTETCATVSCWEENDFRFGSIGKPLPDVEVRIGHENE
                     IQVRGPIVMCGYYNKPLETAATFTEDGWLKTGDAGALDENGNLFITERLKDLMKT"
     PFAM_domain     complement(10400..11761)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3547_0081"
                     /evalue="2.70E-94"
                     /label="ctg1_3547"
                     /locus_tag="ctg1_3547"
                     /protein_end="468"
                     /protein_start="14"
                     /score="316.3"
                     /tool="antismash"
                     /translation="QQQIKHIPHRVALREWSAHGETPYTWQQVGLRVEKLALALCALGV
                     DVQERVAIFAHNSVSWSLIDLAILHLRAITVPVYSTNTAAQTAFVLNDADVRILFVDGQ
                     SQYNAALALRGVCPQLEHIIVMSDSIDMQGCEIACTLDSFAASAQERFLPLLKERIEQA
                     DMSDLFTLIYTSGTTGEPKGVMLNYTNMGAQLRLHDERLTVTAEDVSLCFLPLSHVFER
                     AWSFYVMHSGAQNVYLSDTNQVREAMQSVKPTVMCAVPRFYEKIFSAIHEKVAQAKWHK
                     RAMFKCAIWVGEKRFLTERAGCKPNVVLSAMHKLADKLVLSKLRGILGGRVRFLPAAGA
                     KMDDNVILFFQALGANIKYGYGMTETCATVSCWEENDFRFGSIGKPLPDVEVRIGHENE
                     IQVRGPIVMCGYYNKPLETAATFTEDGWLKTGDAGALDENGNLFITERLKDLMKT"
     CDS_motif       complement(10496..10567)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_3547_0002"
                     /evalue="4.10E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg1_3547"
                     /protein_end="436"
                     /protein_start="412"
                     /score="16.0"
                     /tool="antismash"
                     /translation="EIQVRGPIVMCGYYNKPLETAATF"
     CDS_motif       complement(11204..11251)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_3547_0001"
                     /evalue="1.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_3547"
                     /protein_end="200"
                     /protein_start="184"
                     /score="24.1"
                     /tool="antismash"
                     /translation="LIYTSGTTGEPKGVML"
     CDS             complement(12166..13119)
                     /gene_functions="regulatory (smcogs) SMCOG1125:LysR family
                     transcriptional regulator (Score: 228.5; E-value: 1.9e-69)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3548"
                     /transl_table=11
                     /translation="MSAQSEVMSLAENGSTELVQLRNVDLNLLTVFDAVMQVQNITRAA
                     HALGMSQPAVSNAVARLKVMFNDELFMRYGRGIQPTHRAYQLFGSVRQALQIVQNELPG
                     SGFNPLISERVFNVAICSPLDIRLTAKLFNQIKDSASHVQLHLNSSVNENIERKLRYQE
                     KDFLISYSRFESDEYSCEPLFKDEFVLAVSKNHPRINNMVSAQQLLVEQHAVVGLNLFS
                     SLSRGYYESSELARCIAYQGTDMNSVLSVVSKTEMVAIAPRWLVEEYAEHLNLSAVLLS
                     DIERERTCYLSWHHAAERDSGHQWMKSVLSEFGSKF"
     PFAM_domain     complement(12190..12768)
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3548_0083"
                     /evalue="6.90E-20"
                     /label="ctg1_3548"
                     /locus_tag="ctg1_3548"
                     /protein_end="310"
                     /protein_start="117"
                     /score="71.4"
                     /tool="antismash"
                     /translation="VAICSPLDIRLTAKLFNQIKDSASHVQLHLNSSVNENIERKLRYQ
                     EKDFLISYSRFESDEYSCEPLFKDEFVLAVSKNHPRINNMVSAQQLLVEQHAVVGLNLF
                     SSLSRGYYESSELARCIAYQGTDMNSVLSVVSKTEMVAIAPRWLVEEYAEHLNLSAVLL
                     SDIERERTCYLSWHHAAERDSGHQWMKSVL"
     PFAM_domain     complement(12871..13044)
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3548_0082"
                     /evalue="2.70E-16"
                     /label="ctg1_3548"
                     /locus_tag="ctg1_3548"
                     /protein_end="83"
                     /protein_start="25"
                     /score="59.4"
                     /tool="antismash"
                     /translation="LNLLTVFDAVMQVQNITRAAHALGMSQPAVSNAVARLKVMFNDEL
                     FMRYGRGIQPTHR"
     CDS             13893..15479
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 417.1;
                     E-value: 1.7e-126)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3549"
                     /sec_met_domain="HMGL-like (E-value: 1.1e-105, bitscore:
                     351.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKMQIAMALERMGVDVMEV
                     GFPVSSPGDFESVQTIARNIKNSRVCGLARCVDKDIDVAAEALRVAEAFRIHVFLATST
                     LHVESKLKKSFEDVVAMAVHSVKRARNYTDDVEFSCEDAGRTPLDNLCRIVEAAIKAGA
                     TTINIPDTVGYTTPYQFGGIITNLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGA
                     RQVEGTINGIGERAGNCALEEVIMAIRTRSEMLGVHTNIHHQEIYRTSQFVSQMCNMPI
                     PGNKAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQVQLNLTSRSGRAAVKHH
                     MEEMGYREGTDFNLDTLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSV
                     QSGTSVMATASVKLNIGGEISAEAATGNGPVDAVYQAINRIAGYDIDIVKYQLSAKGQG
                     KDALGQVDIVANYNGRRFHGVGITTDIVESSALALINVLNNIWRAQQVEKEKQRIHQTQ
                     TTSSHSNQEAV"
     PFAM_domain     13902..14711
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3549_0084"
                     /evalue="2.10E-106"
                     /label="ctg1_3549"
                     /locus_tag="ctg1_3549"
                     /protein_end="273"
                     /protein_start="3"
                     /score="355.4"
                     /tool="antismash"
                     /translation="QVIIFDTTLRDGEQALQASLSVKEKMQIAMALERMGVDVMEVGFP
                     VSSPGDFESVQTIARNIKNSRVCGLARCVDKDIDVAAEALRVAEAFRIHVFLATSTLHV
                     ESKLKKSFEDVVAMAVHSVKRARNYTDDVEFSCEDAGRTPLDNLCRIVEAAIKAGATTI
                     NIPDTVGYTTPYQFGGIITNLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQV
                     EGTINGIGERAGNCALEEVIMAIRTRSEMLGVHTNIHHQEIYRTSQFV"
     aSDomain        13902..15386
                     /aSDomain="TIGR00973"
                     /aSTool="tigrfam"
                     /description="leuA_bact: 2-isopropylmalate synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3549_0031"
                     /evalue="6.40E-247"
                     /identifier="TIGR00973"
                     /label="ctg1_3549"
                     /locus_tag="ctg1_3549"
                     /protein_end="498"
                     /protein_start="3"
                     /score="817.8"
                     /tool="antismash"
                     /translation="QVIIFDTTLRDGEQALQASLSVKEKMQIAMALERMGVDVMEVGFP
                     VSSPGDFESVQTIARNIKNSRVCGLARCVDKDIDVAAEALRVAEAFRIHVFLATSTLHV
                     ESKLKKSFEDVVAMAVHSVKRARNYTDDVEFSCEDAGRTPLDNLCRIVEAAIKAGATTI
                     NIPDTVGYTTPYQFGGIITNLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQV
                     EGTINGIGERAGNCALEEVIMAIRTRSEMLGVHTNIHHQEIYRTSQFVSQMCNMPIPGN
                     KAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQVQLNLTSRSGRAAVKHHMEE
                     MGYREGTDFNLDTLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSG
                     TSVMATASVKLNIGGEISAEAATGNGPVDAVYQAINRIAGYDIDIVKYQLSAKGQGKDA
                     LGQVDIVANYNGRRFHGVGITTDIVESSALALINVLN"
     PFAM_domain     15000..15392
                     /aSDomain="LeuA_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08502.12"
                     /description="LeuA allosteric (dimerisation) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3549_0085"
                     /evalue="1.40E-36"
                     /label="ctg1_3549"
                     /locus_tag="ctg1_3549"
                     /protein_end="500"
                     /protein_start="369"
                     /score="125.4"
                     /tool="antismash"
                     /translation="QVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGTSVMATASVKLN
                     IGGEISAEAATGNGPVDAVYQAINRIAGYDIDIVKYQLSAKGQGKDALGQVDIVANYNG
                     RRFHGVGITTDIVESSALALINVLNNI"
     CDS             15482..16573
                     /locus_tag="ctg1_3550"
                     /transl_table=11
                     /translation="MSKTHHIAVLPGDGIGPEIMAQAYKTIDAVRQRFGLRISTSEYDV
                     GGAAIDKHGTPLPAATIAGCEQASAILFGSVGGPKWENLPPAQQPERGALLPLRKHFKL
                     FSNLRPARLYEGLEEFCPLRSDIAARGFDILCVRELTGGIYFGQPKGREGQGMHERAFD
                     TEVYHRFEIERIARIAFEAARKRRGKVTSIDKANVLQSSILWREIATEIGKDYPDVALN
                     HMYIDNATMQLIKDPSQFDVMLCSNIFGDILSDECAMITGSMGMLPSASLNEQGFGLYE
                     PAGGSAPDIAGKNIANPIAQILSFALLLRYSLDADDAANAVEQAVNKALEQGFRTGDLA
                     GDGQAISTSEMGDVIARFIAQEA"
     aSDomain        15497..16543
                     /aSDomain="TIGR00169"
                     /aSTool="tigrfam"
                     /description="leuB: 3-isopropylmalate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3550_0032"
                     /evalue="7.30E-166"
                     /identifier="TIGR00169"
                     /label="ctg1_3550"
                     /locus_tag="ctg1_3550"
                     /protein_end="354"
                     /protein_start="5"
                     /score="549.4"
                     /tool="antismash"
                     /translation="HIAVLPGDGIGPEIMAQAYKTIDAVRQRFGLRISTSEYDVGGAAI
                     DKHGTPLPAATIAGCEQASAILFGSVGGPKWENLPPAQQPERGALLPLRKHFKLFSNLR
                     PARLYEGLEEFCPLRSDIAARGFDILCVRELTGGIYFGQPKGREGQGMHERAFDTEVYH
                     RFEIERIARIAFEAARKRRGKVTSIDKANVLQSSILWREIATEIGKDYPDVALNHMYID
                     NATMQLIKDPSQFDVMLCSNIFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGS
                     APDIAGKNIANPIAQILSFALLLRYSLDADDAANAVEQAVNKALEQGFRTGDLAGDGQA
                     ISTSEMGDV"
     PFAM_domain     15497..16546
                     /aSDomain="Iso_dh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00180.22"
                     /description="Isocitrate/isopropylmalate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3550_0086"
                     /evalue="1.80E-137"
                     /label="ctg1_3550"
                     /locus_tag="ctg1_3550"
                     /protein_end="355"
                     /protein_start="5"
                     /score="458.4"
                     /tool="antismash"
                     /translation="HIAVLPGDGIGPEIMAQAYKTIDAVRQRFGLRISTSEYDVGGAAI
                     DKHGTPLPAATIAGCEQASAILFGSVGGPKWENLPPAQQPERGALLPLRKHFKLFSNLR
                     PARLYEGLEEFCPLRSDIAARGFDILCVRELTGGIYFGQPKGREGQGMHERAFDTEVYH
                     RFEIERIARIAFEAARKRRGKVTSIDKANVLQSSILWREIATEIGKDYPDVALNHMYID
                     NATMQLIKDPSQFDVMLCSNIFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGS
                     APDIAGKNIANPIAQILSFALLLRYSLDADDAANAVEQAVNKALEQGFRTGDLAGDGQA
                     ISTSEMGDVI"
     aSDomain        16576..17970
                     /aSDomain="TIGR00170"
                     /aSTool="tigrfam"
                     /description="leuC: 3-isopropylmalate dehydratase, large
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3551_0033"
                     /evalue="2.30E-267"
                     /identifier="TIGR00170"
                     /label="ctg1_3551"
                     /locus_tag="ctg1_3551"
                     /protein_end="465"
                     /protein_start="0"
                     /score="884.9"
                     /tool="antismash"
                     /translation="MAKTLYQKLFDAHVVYEAKNETPLLYIDRHLVHEVTSPQAFDGLR
                     AMGRPVRQTSKTFATMDHNVSTQTKDINACGDMARIQMQELMKNCKEFGVQLYDLNHPF
                     QGIVHVIGPEQGMTLPGNTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRA
                     KTMKIEIIGDAAEGITAKDIVLAVIGKIGHAGGTGHVVEFCGKAVEALSMEGRMTLCNM
                     AIEMGAKAGLVAPDETTFTYLKGRQFAPQGDNWEKAVEYWRTLKSDAGAQFDAIITLNA
                     GEIAPQVTWGTNPGQVIAINQPIPTPESFSDPIERASAEKALAYMDLAAGVKLTDVAID
                     KVFIGSCTNSRIEDLRAAAAIAKGRKVANGVQAIVVPGSGPVKAQAESEGLDKIFIEAG
                     FEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVSGH
                     FADIREL"
     CDS             16576..17988
                     /locus_tag="ctg1_3551"
                     /transl_table=11
                     /translation="MAKTLYQKLFDAHVVYEAKNETPLLYIDRHLVHEVTSPQAFDGLR
                     AMGRPVRQTSKTFATMDHNVSTQTKDINACGDMARIQMQELMKNCKEFGVQLYDLNHPF
                     QGIVHVIGPEQGMTLPGNTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRA
                     KTMKIEIIGDAAEGITAKDIVLAVIGKIGHAGGTGHVVEFCGKAVEALSMEGRMTLCNM
                     AIEMGAKAGLVAPDETTFTYLKGRQFAPQGDNWEKAVEYWRTLKSDAGAQFDAIITLNA
                     GEIAPQVTWGTNPGQVIAINQPIPTPESFSDPIERASAEKALAYMDLAAGVKLTDVAID
                     KVFIGSCTNSRIEDLRAAAAIAKGRKVANGVQAIVVPGSGPVKAQAESEGLDKIFIEAG
                     FEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVSGH
                     FADIRELATAAV"
     PFAM_domain     16597..17946
                     /aSDomain="Aconitase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00330.22"
                     /description="Aconitase family (aconitate hydratase)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3551_0087"
                     /evalue="6.90E-163"
                     /label="ctg1_3551"
                     /locus_tag="ctg1_3551"
                     /protein_end="457"
                     /protein_start="7"
                     /score="543.0"
                     /tool="antismash"
                     /translation="KLFDAHVVYEAKNETPLLYIDRHLVHEVTSPQAFDGLRAMGRPVR
                     QTSKTFATMDHNVSTQTKDINACGDMARIQMQELMKNCKEFGVQLYDLNHPFQGIVHVI
                     GPEQGMTLPGNTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEI
                     IGDAAEGITAKDIVLAVIGKIGHAGGTGHVVEFCGKAVEALSMEGRMTLCNMAIEMGAK
                     AGLVAPDETTFTYLKGRQFAPQGDNWEKAVEYWRTLKSDAGAQFDAIITLNAGEIAPQV
                     TWGTNPGQVIAINQPIPTPESFSDPIERASAEKALAYMDLAAGVKLTDVAIDKVFIGSC
                     TNSRIEDLRAAAAIAKGRKVANGVQAIVVPGSGPVKAQAESEGLDKIFIEAGFEWRLPG
                     CSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVSG"
     CDS             18003..18620
                     /locus_tag="ctg1_3552"
                     /transl_table=11
                     /translation="MATSTQSGLIKHSGIVVPLDAANVDTDAIIPKQFLQKVTRTGFGQ
                     HLFNDWRFLDDAGQQPNPDFILNQPEFKGASILLTRENFGCGSSREHAPWALTDYGFKV
                     VIAPSFADIFYGNSFNNQLLPVTLSEAEIDELFAQVEAAPGMSFTVDLETQTVQAGDKS
                     YSFELDSFRRHCMMNGLDSIGLTLQHEAAISEYEGKLPEFLR"
     aSDomain        18024..18581
                     /aSDomain="TIGR00171"
                     /aSTool="tigrfam"
                     /description="leuD: 3-isopropylmalate dehydratase, small
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3552_0034"
                     /evalue="3.00E-97"
                     /identifier="TIGR00171"
                     /label="ctg1_3552"
                     /locus_tag="ctg1_3552"
                     /protein_end="193"
                     /protein_start="7"
                     /score="321.9"
                     /tool="antismash"
                     /translation="GLIKHSGIVVPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFNDWR
                     FLDDAGQQPNPDFILNQPEFKGASILLTRENFGCGSSREHAPWALTDYGFKVVIAPSFA
                     DIFYGNSFNNQLLPVTLSEAEIDELFAQVEAAPGMSFTVDLETQTVQAGDKSYSFELDS
                     FRRHCMMNGLDSIGLTLQHEAAI"
     PFAM_domain     18027..18392
                     /aSDomain="Aconitase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00694.21"
                     /description="Aconitase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3552_0088"
                     /evalue="5.60E-39"
                     /label="ctg1_3552"
                     /locus_tag="ctg1_3552"
                     /protein_end="130"
                     /protein_start="8"
                     /score="133.5"
                     /tool="antismash"
                     /translation="LIKHSGIVVPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFNDWRF
                     LDDAGQQPNPDFILNQPEFKGASILLTRENFGCGSSREHAPWALTDYGFKVVIAPSFAD
                     IFYGNSFNNQLLPVTLSE"
     CDS             complement(19028..19231)
                     /locus_tag="ctg1_3553"
                     /transl_table=11
                     /translation="MFRSPVSTCVSMSLLAKATDESPVARGLSTRALLSETPSPLRFGI
                     AHPGRPKLRHDIPVVPALPAKT"
     CDS             complement(19338..20810)
                     /locus_tag="ctg1_3554"
                     /transl_table=11
                     /translation="MGKLTPLKPIPSLISIAIALIIWFVIPVPEGVSPNAWHLLALFVG
                     TIAAIIGKAMPIGAVSIIAIALVAVTQVTNPGKPTAALDDALSGFSNQLIWLIGISIMI
                     SLSLNKTGLGARIGYYFISLFGKKTLGIAYALALAETTLAPVTPSNTARGGGIIHPIMK
                     SIADSFGSKPEPGSTEKIGRYLSLVNYNINPVTSAMFITATAPNPLIVNLLLKGTDSTF
                     ELTWSMWAIAALVPGIISLLVMPLIVYWLYPPEIKSTPDAPRFAKDKLRDLGPISLAEK
                     ITLGVFALLLFLWAGIPAFLLGSDWTVNPTTAAFIGLSILLASGVLSWDDVLKHKGAWD
                     TVVWFAALVMMATYLGKLGLISWLSQTVGGAISHLGMGWIGGMILLTLVYVYSHYFFAS
                     TTAHITAMFAAFFAAGLALGAPPALLGLVLAFSSSLMMSLTHYGTGTAPIIFGSGYVTL
                     GEWWKTGFVLSVINLLIWMVIGSLWWKWLGYW"
     PFAM_domain     complement(19341..20774)
                     /aSDomain="Na_sulph_symp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00939.21"
                     /description="Sodium:sulfate symporter transmembrane
                     region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3554_0089"
                     /evalue="1.70E-142"
                     /label="ctg1_3554"
                     /locus_tag="ctg1_3554"
                     /protein_end="490"
                     /protein_start="12"
                     /score="475.9"
                     /tool="antismash"
                     /translation="LISIAIALIIWFVIPVPEGVSPNAWHLLALFVGTIAAIIGKAMPI
                     GAVSIIAIALVAVTQVTNPGKPTAALDDALSGFSNQLIWLIGISIMISLSLNKTGLGAR
                     IGYYFISLFGKKTLGIAYALALAETTLAPVTPSNTARGGGIIHPIMKSIADSFGSKPEP
                     GSTEKIGRYLSLVNYNINPVTSAMFITATAPNPLIVNLLLKGTDSTFELTWSMWAIAAL
                     VPGIISLLVMPLIVYWLYPPEIKSTPDAPRFAKDKLRDLGPISLAEKITLGVFALLLFL
                     WAGIPAFLLGSDWTVNPTTAAFIGLSILLASGVLSWDDVLKHKGAWDTVVWFAALVMMA
                     TYLGKLGLISWLSQTVGGAISHLGMGWIGGMILLTLVYVYSHYFFASTTAHITAMFAAF
                     FAAGLALGAPPALLGLVLAFSSSLMMSLTHYGTGTAPIIFGSGYVTLGEWWKTGFVLSV
                     INLLIWMVIGSLWWKWLGYW"
     aSDomain        complement(19359..20732)
                     /aSDomain="TIGR00785"
                     /aSTool="tigrfam"
                     /description="dass: transporter, divalent anion:Na+
                     symporter (DASS) family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3554_0035"
                     /evalue="5.90E-116"
                     /identifier="TIGR00785"
                     /label="ctg1_3554"
                     /locus_tag="ctg1_3554"
                     /protein_end="484"
                     /protein_start="26"
                     /score="385.7"
                     /tool="antismash"
                     /translation="PVPEGVSPNAWHLLALFVGTIAAIIGKAMPIGAVSIIAIALVAVT
                     QVTNPGKPTAALDDALSGFSNQLIWLIGISIMISLSLNKTGLGARIGYYFISLFGKKTL
                     GIAYALALAETTLAPVTPSNTARGGGIIHPIMKSIADSFGSKPEPGSTEKIGRYLSLVN
                     YNINPVTSAMFITATAPNPLIVNLLLKGTDSTFELTWSMWAIAALVPGIISLLVMPLIV
                     YWLYPPEIKSTPDAPRFAKDKLRDLGPISLAEKITLGVFALLLFLWAGIPAFLLGSDWT
                     VNPTTAAFIGLSILLASGVLSWDDVLKHKGAWDTVVWFAALVMMATYLGKLGLISWLSQ
                     TVGGAISHLGMGWIGGMILLTLVYVYSHYFFASTTAHITAMFAAFFAAGLALGAPPALL
                     GLVLAFSSSLMMSLTHYGTGTAPIIFGSGYVTLGEWWKTGFVLSVINLLIWMVIGSLWW
                     "
     CDS             complement(21004..21807)
                     /locus_tag="ctg1_3555"
                     /transl_table=11
                     /translation="MLPMELRTSCGVSAAMRMRIQQTLCALEEEYQIRILYACESGSRG
                     WGFASTDSDYDVRFIYVHRPEWYLRVESGRDVIEMPIDDELDVCGWELRKTLGLIKRSN
                     PTLMEWLDSPIVYRNEERATAALRALLPDYFSGLRGRYHYLSMARKNFRGYLQGEEVRL
                     KKYFYVLRPLLAVRWIEAGKGVPPMRFEQLVAGTVDDADLLDEIAQLLHAKCEASEAKY
                     GPRMKKIHEFIQYELDDNLSRCEMVDNVACSDDVLNRLLFQEVNC"
     PFAM_domain     complement(21025..21762)
                     /aSDomain="RlaP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10127.11"
                     /description="RNA repair pathway DNA polymerase beta
                     family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3555_0090"
                     /evalue="4.90E-91"
                     /label="ctg1_3555"
                     /locus_tag="ctg1_3555"
                     /protein_end="261"
                     /protein_start="15"
                     /score="304.8"
                     /tool="antismash"
                     /translation="MRMRIQQTLCALEEEYQIRILYACESGSRGWGFASTDSDYDVRFI
                     YVHRPEWYLRVESGRDVIEMPIDDELDVCGWELRKTLGLIKRSNPTLMEWLDSPIVYRN
                     EERATAALRALLPDYFSGLRGRYHYLSMARKNFRGYLQGEEVRLKKYFYVLRPLLAVRW
                     IEAGKGVPPMRFEQLVAGTVDDADLLDEIAQLLHAKCEASEAKYGPRMKKIHEFIQYEL
                     DDNLSRCEMVDNVACSDDVLNRLL"
     CDS             complement(21807..22943)
                     /locus_tag="ctg1_3556"
                     /transl_table=11
                     /translation="MRKNIIIQKGQIGLLTKKGDYQKVLEAGEYRFFDWTNQLAVTVVN
                     LSDSRVEPALAEHLRSYQPEWVERYCTAVDLSEQEIGLRYENDILQEILPPGTRRLYWL
                     NGNQQRIERIEANNVEVPSEIVAALHQPKLRNRTIKGGEGVLLVQVPAWHVGILKIDGA
                     TQALLSPGISGYWRFNHAVEAEIVDTRLQVLEVSGQEILTRDKVNLRLNLAANWRYSDV
                     LQSFALVAKPLEHIYRELQFALREAVGTRTLDELLENKQIIDDIVSEQVSRKLVGYGIE
                     VVSLGVKDIVLPGDMKTILSRVVEAEKLAQANVIRRREETSATRSLLNTAKVMENNPVA
                     LRLKELETLERVAERIDKISVFGGLDQVLNGLIQIKGV"
     PFAM_domain     complement(21984..22499)
                     /aSDomain="Band_7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01145.27"
                     /description="SPFH domain / Band 7 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3556_0091"
                     /evalue="2.30E-22"
                     /label="ctg1_3556"
                     /locus_tag="ctg1_3556"
                     /protein_end="320"
                     /protein_start="148"
                     /score="79.9"
                     /tool="antismash"
                     /translation="QVPAWHVGILKIDGATQALLSPGISGYWRFNHAVEAEIVDTRLQV
                     LEVSGQEILTRDKVNLRLNLAANWRYSDVLQSFALVAKPLEHIYRELQFALREAVGTRT
                     LDELLENKQIIDDIVSEQVSRKLVGYGIEVVSLGVKDIVLPGDMKTILSRVVEAEKLAQ
                     ANVIRRREE"
     CDS             23455..25032
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 235.8; E-value:
                     1.5e-71)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3557"
                     /transl_table=11
                     /translation="MKRRVVIGVLGTVLDKRGKRANRWNKWRPTVGLCQQPDLPIDRLE
                     LLYQPRDLGMAQQVSDDIAQLGSTQVCLHQVNLHDPWDFEEVYTAFLDFATHYPFDTDN
                     EEYLIHITTGTHVVQICWFLLAEARYFPASLLQTSPAPKSQEKTEATPAGVYSIIDLDL
                     SRYSKLTRRFQREQQASISFLKSGIATRNTTFNTLIDQIERVALRSTAPILLTGPTGAG
                     KSFLAQRIYQLRQSRHKVSGRFVAVNCATLRGDNAMSTLFGHIKGAFTGALQARSGLLR
                     EADGGVLFLDEIGELGLDEQAMLLKAIEEKRFLPFGSDKEVSSNFQLIAGTHRDMRQWV
                     KQGRFREDLYARINMWTFPLPSLAQRREDIEPNLDFELNRYSQEQQAQVRFNKEARQRY
                     LQFACSEQAEWRGNFRELAASVTRMATLADTGRIDDELVQEEIARLQQNWQKDQPEILP
                     DLPELDLFDRSQLASVISVCRSSDSLSEAGRKLFSVSRQLKKQPNDADRLRKYLARFGL
                     SWESIKGE"
     PFAM_domain     23458..24015
                     /aSDomain="RtcR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06956.13"
                     /description="Regulator of RNA terminal phosphate cyclase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3557_0092"
                     /evalue="6.50E-81"
                     /label="ctg1_3557"
                     /locus_tag="ctg1_3557"
                     /protein_end="187"
                     /protein_start="1"
                     /score="270.2"
                     /tool="antismash"
                     /translation="KRRVVIGVLGTVLDKRGKRANRWNKWRPTVGLCQQPDLPIDRLEL
                     LYQPRDLGMAQQVSDDIAQLGSTQVCLHQVNLHDPWDFEEVYTAFLDFATHYPFDTDNE
                     EYLIHITTGTHVVQICWFLLAEARYFPASLLQTSPAPKSQEKTEATPAGVYSIIDLDLS
                     RYSKLTRRFQREQQASISFLKSG"
     PFAM_domain     24022..24522
                     /aSDomain="Sigma54_activat"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00158.28"
                     /description="Sigma-54 interaction domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3557_0093"
                     /evalue="1.10E-50"
                     /label="ctg1_3557"
                     /locus_tag="ctg1_3557"
                     /protein_end="356"
                     /protein_start="189"
                     /score="171.7"
                     /tool="antismash"
                     /translation="TRNTTFNTLIDQIERVALRSTAPILLTGPTGAGKSFLAQRIYQLR
                     QSRHKVSGRFVAVNCATLRGDNAMSTLFGHIKGAFTGALQARSGLLREADGGVLFLDEI
                     GELGLDEQAMLLKAIEEKRFLPFGSDKEVSSNFQLIAGTHRDMRQWVKQGRFREDLYAR
                     INMW"
ORIGIN
        1 agtgggcgct tacctttatc acgatcgcca ccgcagccaa agacgcacca cagttgccct
       61 ttacagtgca gacgagcagc ttcgagggct ttttccagcg catccggcgt atgggcgtaa
      121 tcgacaacga cggtaggttt tcctggtgca gtgaaaactt ccatacgacc acatactggc
      181 tgcagctggg atgaagtttt gcacagcaca tccaatggat aaccaagcgc cagcatcgtt
      241 gccgcggcca ccagcaggtt gctcacgtta aatgcgccca tcaggcggct ttccagcaca
      301 cccttacccc atgacgaatc aaaactgatg cttgcaccgc tatcgtgata gtcaacttgg
      361 cttgcagaaa cccagcgtcc agcccagttc tccggcagac gctgttccat ggtgacagct
      421 accgcatccg gtgacttagc caaccaacgc tgaccgactt catcatcggc attaataatc
      481 ttttcaccgc tgtgatgggt tgagaacagc agccatttag cctgttcgta gtgctccata
      541 tcgccatgat aatcaaggtg atcgcggctc agatttgtga acgcagaagc tgcaaacggc
      601 agcgccgcga cacgatcctg aaccagacca tgtgaggaga cttccatcgc tgccagcgta
      661 gcgccttgag ataccagact acgcaacagg tgttgaacat caacggctga accggtggtg
      721 ttctcgcttg gatgaacctg ccctaacaaa ccatttccta cggttcccat caccgcgcta
      781 gtttcaccta acaactgccc ccactgcgcc agtagttgcg taatggttgt tttaccgttg
      841 gtacccgtca cgccgattaa gcgtaaatca gcacctggct gatggtaaaa gcggcctgcc
      901 agcgccgaaa gacgctgatt taactgactc aggtaaatga cgggaacacc atggctctca
      961 cgaatggtgc catcttctgc ttccccatct gcctctgcga tgactgcagc aacgccttgc
     1021 gctatcgctt gcggaatata atggcgacca tctgcggtgt ggccaacaat cgccacaaac
     1081 agatcgcccg cagccgcaat gcggctgtct aatgtcattt ctcgcaaaac gcgctccgga
     1141 gcatctgcta cccaaggagc caaaagcgcg cgcaaattac gatctgccac ctgaaccctc
     1201 ttttttattg ttcgctaatt cgtttttatc acccgtgggc aacgcgtccg gctcaacgtt
     1261 catggtgcgc agtacgccac ccatgatagc gccaaagatc ggggcggata ccgcaccacc
     1321 gtaatacttc cctgcctgcg gatcgttgat gaccacaacc agagcaaatc gaggattact
     1381 cgctggcgct acgcctgcgg tgtaagcaat gtacttatca acataacggc catcagggcc
     1441 tactttcttc gccgtaccgg ttttaatcgc aatacggtag cctttaatgg cggctttagt
     1501 accaccacca cccggcaacg ctacgctttc catcatatgt acgaccgtac gcacaattgg
     1561 ctcagggaac acacgctcac ctggcaccgg cggatcgact tttgttatcg acagcgggcg
     1621 atagataccc aagctgccaa tcgttgcata gacacgtgct agctgtaacg gcgttaccat
     1681 cagcccatat ccgaaagaaa aggtggccct ctctatgtca gaccaccgtt gtttttttgg
     1741 gtacatgcca ctgctttctc cgaccagccc caaattggtc gccttaccca atccaaagtg
     1801 cgagtaggtt tctaccagcg cagaggacgg catcgctaac gccagctttg atacaccaac
     1861 gttactcgat ttctggagaa tccccgtgat agagagttct gcatagcggg caacgtcttt
     1921 aatctggtgc ccgttaacaa aataggggag cgtattcagt acgctgttct ctttcaccac
     1981 gttgtgttgc aacgcggtca tgactaccat cggttttacc gtagaacctg gctcgaaaat
     2041 atcggtgata gcgcggttac gcatggcctc ttttggcgta tctgctagat tgttcgggtt
     2101 gtatgaaggg ctattagcca tcgccaatac ttcacccgtg ttcacatcaa ccaacaccgc
     2161 agtgcccgat tcggctttgt taaatgcgac ggcattgttc agttcacggt aaaccagcgc
     2221 ttgtaaacgt tcatcaatac tgagggcaag attatgagcg gcctgactgt caacggacga
     2281 aatatcttca ataacgcgac caaagcggtc tttgcgaacg gtacgctcgc cgggctggcc
     2341 agttaaccaa cggtcaaagc tcttttcaac gccttcaatt ccctgaccat caatgttggt
     2401 caccccgata atgtgagcag tcacttgccc tgcagggtaa taacggcgag attcttgctt
     2461 ttggaaaatg cctggaagtt tgagtttgtg aatgtaatca gccatcgccg ggttaacctg
     2521 acgcgccaaa taaacgaaac ggcctttggg gttggcgttg atacgcgcag ccattttgtc
     2581 tagcggcatt tctaatgcat cagccaacgc tttccaacgg gtatctaagg tgataccacc
     2641 gtgttcgttc acttctttcg gatcagccca aatcgcattt accggcacac tcaccgcgag
     2701 cggtcgccca gccctgtcgc tgatcattcc acgcgaagtg aggataggct gagttcttag
     2761 tgaacgcgca tcgccttcac gcaccaaacg gtcggggtta atcacctgta gataggcaac
     2821 tcgtcctaat aaacccatta atgcaataaa tatgcacccg cagagcaacg caaaacgcca
     2881 gctgacaaag ctggcctgat cttcctgacg ctttaacttt ccgggtcgca ctgctttcat
     2941 tgattacaca tttacctacg tcaaaggtgg ttcattgaaa atataaccgg ttaaatacgc
     3001 tattgtttaa ccacgatatt ctcttgagat gggtctacgt gctgcatttg cagcttctct
     3061 gttgcaattc gttccacgcg gctgtgatcg cctaacgcat tctcttccag aatcaaattg
     3121 cgccactcga tatctagagc gtcacgctca agcactaact gctcgcgctg cgcggtcaac
     3181 aagcgtgttt tatgcgttgt tgttaccacc agcacagccg aaaccagcac accgataaac
     3241 agaatcagag gcagcttgcc gtggcggaga atatctccgc caataacggc aactagcgtg
     3301 tggcgctcgt taccgatcat tcaaccgtcc tttccgcaaa acgcaggaca gaacttcgtg
     3361 ctcgtgggtt agcgcttact tcatcactgc ttggtttcat tttcccgagc gctttcaact
     3421 tacgaccacc ttggctgcgc agttgagctt cggttaaagg gataccagct ggaacctgag
     3481 gaccacggct atggtggcga ataaactgtt taacaatgcg atcttccaac gagtggaagc
     3541 tgataaccga cagacgtcct tctggggata gaatttccaa cgcgccgttc agtgcgcgtt
     3601 caatctcttc cagttcgcta ttgatataga tacggatcgc ttggaagctg cgcgtggcag
     3661 gatgcttatg cttttcacgg aatgggcttg cgttcgcaat cagcgttgcc aattcatgcg
     3721 tccgtgtcat cggctcaaga cgattacgct caacgatggc gcgagcaatg cgcttagcaa
     3781 agcgttcttc gccgaaggtt ttcagcaccc aggcaatatc ttcttcttcc gctttcatca
     3841 accactctgc ggcagaaagg ccacgggttg gatccatacg catatcaagc ggtccgtcac
     3901 gcataaagga gaaaccacgc tcagcatcgt caagctgtgg tgaagacact ccaagatcaa
     3961 gcaaaacacc gttgatttga ccttccagac ctaattcgcg tacataggtc gccatatcgg
     4021 agaatgggcc gtggatgata gaaaagcgtg ggtcggtgat ttctgctgct gcggcaatag
     4081 cctgcgggtc acgatcgata gccagcaagc gtccttccgg tcccaactga gacaaaataa
     4141 gacgggaatg accaccgcga ccaaaagtgc catcaatata aatgccgtta ctgcgcagat
     4201 taaggccgtt taccgcctca tcaagcaaca cggtcttgtg ttggtaattt tcttctgaca
     4261 tgactataac gacaaatcct gtagccgttc ggataaaggc tccgtaacgg tctgttgtgc
     4321 gtcaatatct tccttgactt gttgatacca gttttcttca tcccacagct caaacttatt
     4381 gaactgccca actagcatca cttgttttgt gagtcctgcg tgctgacgca acgtacttgc
     4441 tatcagcaat cgacccgcgc tatccatctg acactcactc gcatgaccta acagcagacg
     4501 ctgaatgcgg cgctctacag gattcatgct cgataaacgc gaaagctttt gttcaatcac
     4561 ttcccactga ggcagggtat aaagcaatag gcatggttga tggagatcga tggtgcaaac
     4621 catttgacct tgcgattcct caagcagtaa ttcgcgatag cgcatcggaa ccgctaagcg
     4681 tcctttaccg tcaaggttga tggttgttgc gccacgaaac atacctaaat tacccctcgt
     4741 tgccccatct caccacttta ctccacaaat tcccacataa ggaagtttac ggagggtagg
     4801 aaaaccttgt caagccagag cggatgcggt ttgggattat ttttgcttga agtgaattta
     4861 aaaccttcca ctatgaaaag tcctaaagag gaataataaa attaacatca tgataaatta
     4921 agggaaattc ttggagggaa gtgtcagtga ctcgaaacac agaaatttta ccaaaaatta
     4981 aaatttaacc agactttgca atatagctct cattttgaac atgtcttgga taatttacat
     5041 acgctttaca ttggtaaagc aaagactaat tcagcataag ttattcaatg ccagaaatta
     5101 aaaatacctt ttaacatcaa tcaattaatt aaaaaacctt catttaattt tttctgtctg
     5161 acattttatc ttactttatc gtcagataat aatggcttta ggcactaaat atctaactgc
     5221 tttttttaaa tcgtaattta gataaattta cctctgaata acgttcacct cagatagttc
     5281 tcaaatatca attttatttt gcaaacctcc cgatttggcg gcgaactcgt gatcgacaaa
     5341 cgttatttgt atgattttca cacaacaaat tgaaagaaaa caaaaatttt aacgccacgg
     5401 taagaaatca tgaaattctc ttcggcgcgc tactctaaga gttttttgta gcaaaagtca
     5461 ttataaatta aaatttatag ctagttaaaa aacaaacagc aatcatgtat gctatttaag
     5521 caaccaaaat gcagttcata acaccaacaa aagcgcaaca aaacagtatt aatgactagt
     5581 ttcaaaatgg agttagccgt tatgttctca cccgcttcac gtgcccgcag cgctgccgca
     5641 gatatttttg cgctggtagt ttattccttt atcgtcggca tgctgattga agtttttatt
     5701 tctggcatga gctttaatca gtcgttgtca tctcgcttgc tttccatccc cgtcaatatt
     5761 cttattgctt ggccctatgg cgtgtaccgc gactggttca ttcgccagtc acaacgctgt
     5821 cgttcaaaag gcatggcaaa aatcttggcg gatctgattg cctatgtctc tttccagtca
     5881 ccggtttatg ccattattct gtggtatgtc ggggctgatg gcgcgcaaat cctggctgcg
     5941 gtcaccagta atgcggtggt ttcaatggct atgggcgtcg cctatgggta cttccttgat
     6001 tactgccgta gactcttcaa agtctcgggc tatatcaaag cacaggcata aaaaagcgcc
     6061 ggtaaaaacc ggcgcccatt gatgagataa cactttatta ttgctgctta catccggttt
     6121 agtcgtccgc gctttaataa aacacgacgc atccggctca atcccgcctt cggtttcttc
     6181 ggttcatcta aacttgcgag taccagttcc agaacacgtt cggcaatatc acggtgacgc
     6241 tgaccgactg acagtactgg gcaatccaga aaatctagga gctcattatc accaaaagtc
     6301 gcaatggcca aatcggtagg taaatgcccg tggtgtttca atgtcacatc caaaacccct
     6361 tgcaaaagcg ggaaggaagt cgtgaacaac gcctgcggca tttcattatt ttttaaccag
     6421 ttagagaatg cgacacctgc cgcgtcacgt tcataactgt tggtgtaaag atattgcact
     6481 tcacgtggat cttctcgcca agcatcacga aaaccttgtt cgcgcaggaa actcacggat
     6541 agctcaggaa gtgcgccaag atagagcacc gatttcgctg ggaatttccg taactcttcc
     6601 gccaacatct ccgaatcttc acgatcggca ccgacaacgc taataaagtg ttcaggatcg
     6661 agtgcgcgat ccagcgcaat gatcggcaaa ggatcctttg cccagcgctg gtagaacgga
     6721 tgttctggct gcagcgccgt cgatacgatg atcgcatcaa cctgacgttg tagcagatgt
     6781 tcaatacaac gcatttcatt gtcaggttga tcttctgaac aagcaatgag taactgatag
     6841 ccacgttgac gcgcttggcg ctccagataa tttgcaatac gggtataact ggtattttcc
     6901 agatcaggta taaccaatcc aattgaacgg gtgcgcccag cacgcaatcc tgcggcaacg
     6961 gcgtttggat gatagttatg ctcacgaacc acagccatca ctttctcaac cgtcttatca
     7021 cttacacggt actgtttggc tttaccgtta atgacataac tggccgtcgt ccgcgagacc
     7081 cctgcaagac gcgcgatttc atccaacttc acgttatccc cctcttgagc cagtaaaata
     7141 cattacctgc atcaaatgaa ataagaagac cgaatggcct ttaatagcat tgatctaacc
     7201 gcataaagaa gaaaggagca accggttttg ctgaaaggca tcagcaaata ggaaaaagta
     7261 agaggctcag cacaaagctg agcctccaaa tagcactatt agacagaaaa ttgacctgca
     7321 ttaacgcatt attttgtcac cacgagatac acccacgatg cctgaacgag cgacttcaac
     7381 aatttcagca acctctcgta cggcacttag gaaggcatcg agcttgtcgc tggtgccaac
     7441 tagctgaacg gtgtaaagcg aagctgtgac gtctacgatc tgaccacgga aaatatcggt
     7501 gctacgctta acttcttctc gtccataacc gctagcctgt agcttcacca gcatgatttc
     7561 tcgctctacg tgcgatcctt gtaccaactc actcactcgc agaacatcta ccaatttatg
     7621 cagttgtttt tcaatctgtt ctagcacctt agcgtcaccg acggtttgaa tagtcatacg
     7681 cgaaagcgtg gggtcatcag tcggggctac agtcaggctt tcaatgttgt acccacgctg
     7741 cgaaaacagg ccaaccacgc gggacagtgc gcctgattcg ttttccagta atacagataa
     7801 gatccggcgc attattaagt cctctccgtt ttgcttaacc acatttcatc cattgaccca
     7861 ccgcggatct gcattgggta aacgtgttca gtttcatcga tggtcacatc aacaaacacc
     7921 agacggtttt taaccgccaa tgcctgttct aatttgcttt ccagttcatc cggcgtgcgg
     7981 atagaaatac caacatgtcc ataggcttct gcgagcttta caaaatctgg caacgattcc
     8041 atatatgact gcgagtgacg tcccgcgtaa atcatatctt gccactgctt caccatgcct
     8101 aggaaacggt tgttcaggtt aatcaccacg accggtaaat cgtattgcaa tgcggtagat
     8161 agctcctgaa tattcatctg gatactgcca tcccctgtca cgcaaatcac ggtttcttct
     8221 ggcagggcta atttaatccc aagcgccgcg ggtaaaccga agcccatcgt gcccaaaccg
     8281 cccgagttca cccagcgccg cggtttatca aagccataat agagtgcggc aaacatttgg
     8341 tgctgcccca cgtcagatgc aacataggct tcccctttcg tcagccgatg caaagtttca
     8401 atgacctgct gtggcttaat gcggccactt gtggtgtcgt aactcaagca tttgcgcgca
     8461 cgccattgag caatgctctg ccaccaatca cgcaggccat cgaagtcttg tttaacctct
     8521 ttctgaccta acaactctag gaacgtcgct agtgcctctt tagcatcacc gacgatcgga
     8581 atatccgcat ccacggtttt cgagatcgat gtcggatcga tatcaatatg tagcacagtc
     8641 gcatttgggc aatatttagc aagattattg gtggtgcgat cgtcaaaacg gacaccaacg
     8701 gcaaaaataa catctgcatt atgcatcgcc atgttggctt cataagtgcc gtgcattccc
     8761 aacatcccta ggctttgcgc atgtgatgca gggaagccac ccagccccat caacgaggta
     8821 gtgactggaa tattcaagcg ctcagccagt tcacgcagtt cttcatggca gccagaacta
     8881 atcaccccac cgccggcata gataatcggc tgtttggctg ctaacaacgt ctgcaaggcg
     8941 cgcttaatct gaccacgatg accttgcaag gttgggttat aagaacgcat tttgacactt
     9001 tcagggtatg aataaggcag cttaatcgcc ggactcatga tgtctttagg taaatcgact
     9061 acgactgggc ctgggcgtcc ggtagacgct aaatagaagg cctttttgag aatggtagga
     9121 atatcctcgg tatgcttaac taggaaactg tgtttcacga ctggacggga tatccccacc
     9181 atgtcgcatt cctgaaacgc atcattacca atcagagacg tggccacctg accagagatc
     9241 actaccatcg gcaccgaatc catataagcc gtcgcaatac cggtgatggc attggtcgct
     9301 cccggtcctg atgtgaccag caccacgccc acttctcctg tagcccgcgc aaaaccgtcg
     9361 gccatgtgca ctgcgccttg ttcatgacgc acgagcacat gttcaataca tccaaccgta
     9421 tgcagagcgt cgtaaatatc aagaacggcc ccgcccggat aaccgaatac atgctttact
     9481 ccctgatcga tcaacgatcg aacgaccatc tcggctcctg acaacatctc catggtttgc
     9541 ctcccggctg actttgcgta ggttatatcc agggtttatc actaatgcga atcgtttaag
     9601 agatcgagat acacggggct agcacaccgc ggggcactcc ggcagctaaa gctgctacga
     9661 ccccatcggt gtacttcccc taaaatcacg cttagcaggc cagcattaga gtttatccct
     9721 gtttttatgt gttgtgtttg atttattacc ttaacgtggg aataacaagt gcgcaaacgg
     9781 caaactcaga agcaaaagtg gaggaattgt aaccttgctg gattcttgat ttttttaggc
     9841 ataaaacgct aagagtaagg gtgttagctc cgcgcttatc gctgcaggtg actaaattac
     9901 agaactaaat cattctcagc cctaaaagat agtctgtgat accacacaaa aagaaaacgg
     9961 ccagcagaag cgctggccgt tgataccact gtgatagaaa ttaatgttcc aaatacatgg
    10021 actcgatttc catctgatag cgagaattaa taatttttcg ccgcagtttc agggttgggg
    10081 ttagttctcc ctgctccatc gagaaagctt cgggcagcag cgtaaaacgc ttaacctgct
    10141 caaacttcgc taaacccttt tgcatctcac gtagacgctg atcaaacatt tctacaatat
    10201 ggctatgacg gagtaaatcc agacgatcgt gatattttaa gttgatcgac ttggcgtact
    10261 cttccagcga ctcgaaacaa ggaacgatca aggcagacac aaactttctt gcgtcggcga
    10321 tcacggcaac ctgctcaata aaacgatcct gtgctagcgt accttccacc atttgtggcg
    10381 caatgtattt accattggag gttttcatca gatcttttag gcgttcagta ataaacaagt
    10441 tgccattttc atctaatgcc cccgcatcgc ccgttttcag ccagccatct tccgtaaagg
    10501 ttgccgcagt ttctaacggt ttgttgtagt aaccgcacat aacaatcggt ccgcgcactt
    10561 ggatttcatt ttcgtggcca atgcgaactt caacatcggg cagcggtttg ccgatagaac
    10621 caaagcggaa atcgttctct tcccaacaag ataccgtggc gcaggtttct gtcatgccat
    10681 agccatattt aatatttgcg cccaatgctt ggaagaagag aataacgtta tcatccattt
    10741 ttgccccagc cgcaggcaaa aatcgcacgc gtccccccaa aatcccgcgc agtttgctca
    10801 gtacgagttt atcagccagc ttatgcatag ctgataaaac gacgttcggc ttgcagcctg
    10861 ctcgttcagt gaggaaacgt ttctccccta cccaaattgc acacttaaac atggcgcgtt
    10921 tatgccattt cgcctgtgcc actttttcat ggatggcgct gaaaattttc tcgtagaaac
    10981 gcggcaccgc acacatcact gttggtttca ctgactgcat cgcttcgcgt acctgattgg
    11041 tatcgctgag atacacgttt tgcgcgccac tatgcataac atagaagctc caagcgcgtt
    11101 caaatacgtg cgaaagtggc agaaaacaaa gtgacacatc ctctgctgtt acggtcagac
    11161 gttcgtcatg caaacgcagt tgagcaccca tattggtgta attcagcatg acgcctttcg
    11221 gctcaccggt agtccctgat gtgtagatca gcgtgaacag atcgctcatg tcagcctgtt
    11281 caatacgttc ttttaacaga ggtaaaaagc gttcttgtgc actggccgcg aatgaatcta
    11341 gcgtacatgc aatttcgcag ccctgcatgt cgatactgtc cgacataaca ataatatgct
    11401 caagctgagg gcatactcct cgtaatgcta gcgccgcgtt atattgagat tgaccatcaa
    11461 caaacaaaat acgtacgtct gcatcattga gaacaaatgc cgtctgagct gcggtattcg
    11521 tcgagtaaac aggaaccgtg atcgcacgca ggtgtaagat cgctagatca atcagtgacc
    11581 atgaaaccga gttgtgggca aagatcgcca ctcgttcctg aacatcaaca cctagcgcac
    11641 acaatgccag cgccaatttt tcaacgcgca gtccgacctg ctgccaagta tagggtgttt
    11701 caccgtgagc agaccattca cgtagcgcaa cgcgatgcgg aatatgtttg atctgctgct
    11761 gaatacgttc aaccagatgg tatttattta actcattgat catagaagaa gttcattgaa
    11821 tttatcgaag tggaagtcgc catgagatat aagtgaaaaa tctcattcag cttacagctg
    11881 tgcgctcttt tggcggaagt ctacctgttc tagctgtcgg gtcaacgatt attcaatcca
    11941 taaatgtgag ttatgatcga ttttttgaat gatttatagc catgacatcg acaccataga
    12001 tggaaaatct aggcgcgata gacgaaaaaa tgaaaaacat aaaaaactgg gaaaagaggg
    12061 ttcaggatgt ataaaacact agtttatgag ctattgtgct aaagataaaa atggagagct
    12121 aggctctcca ttttatgtaa tttcaatttt taaattaatt aataattaaa acttactacc
    12181 aaactcgctg aggactgact tcatccactg gtgaccgctg tcacgctctg ccgcatggtg
    12241 ccagctcagg tagcaggtac gctctctttc gatatcactc agaagcacgg cagagagatt
    12301 caaatgctca gcgtattctt caacaagcca acgaggtgca atagcaacca tttctgtttt
    12361 agaaacaacg ctcaatacgc tattcatatc agtaccttga tatgcaatgc agcgtgctaa
    12421 ttcactagac tcataataac cacgactcag cgatgagaag agatttaatc caacaaccgc
    12481 atgctgctca accaataact gctgagcgct aaccatatta ttaatacgcg ggtgattttt
    12541 ggataccgct aaaacaaact catctttgaa taacggctca caggaatatt catcactttc
    12601 aaaacggctg taactgatca ggaagtcttt ttcttgataa cgcaatttac gctcaatatt
    12661 ttcattcacc gatgagttta aatgtaattg aacatgggaa gcgctatctt tgatctgatt
    12721 aaacagcttc gctgttaagc gaatatctaa tgggctacaa attgcaacat tgaaaactct
    12781 ttcgctgatc agcggattaa aacctgaacc tgggagttcg ttctgtacaa tctgcaatgc
    12841 ctgacgaacc gaaccaaaca gctgatatgc acgatgagtt ggctgaatac ctcggccata
    12901 gcgcataaac aattcatcat tgaacatcac ttttaagcga gcaacggcat tacttaccgc
    12961 gggttgagac atgcccaaag catgtgccgc tcgggtaata ttttgcacct gcattaccgc
    13021 atcaaaaacg gtaagcaaat taagatcaac gtttcttaac tgaaccagtt ctgtacttcc
    13081 attctcggcc aatgacataa cttcactttg tgctgacata catcacccta atataaataa
    13141 ctttgttaac gtcgaaatta aaacaaacga cattacggtt tgattaaaat tctgagggca
    13201 aatgaattca taaatgatag atagccatta agctttatga attaaagcac tcacatgatt
    13261 taagataaat ttatacaatt cgaattacaa tgacatgcga gtacaacaat cactcattag
    13321 gcagccactc attcaatatt gatacattct actgattaat gatttagttg tacttaaaat
    13381 tcaaggaagc aatgattaaa taacaatgaa taatacccat gtatatttat ggaaatactg
    13441 ttctcatcca attagttaca ataaaaacgc atgaagctat agaataagcc gaacgcaatt
    13501 agcacactaa tgtttcgaat aaagattgaa ggaacttcac aattctgtat tacatgacaa
    13561 cgggaacatt aatcactatc acgcaagaag atgagttttc ttcactcaac taaatagccg
    13621 ttgacaaggt taccgctatc cagtatcact ttaagcattg agtttattca cccagattaa
    13681 gagcggaatc acatgatcaa gatgactcgt ctcctaggcc tcctccttct cgcatccaat
    13741 ttgcgcggtg agcctgtggg cggtaatcaa aactgattcc aaccaaacac aagaaagccc
    13801 gcgcaaatgc gcgggctttt ttttgcatca aaagcagcgc aacgcgttaa taaaaactga
    13861 tgagttaata aaaactgcga ggagcaacct gcatgagcca acaagtcatt attttcgaca
    13921 ccacgctgcg cgatggtgaa caagcgttac aagccagcct gagcgtcaaa gaaaagatgc
    13981 agatcgcaat ggccttagag cgcatgggcg ttgacgtgat ggaagttggc tttcccgttt
    14041 cttcaccagg cgattttgaa tcagtacaaa ccatcgcacg caacatcaaa aatagccgag
    14101 tctgtggctt agcgcggtgc gtagataaag atatcgacgt tgcggctgaa gcgctgcgcg
    14161 tggctgaagc cttccgcatc catgtctttt tggctacctc aacgttacat gttgaatcta
    14221 aactgaaaaa gtcctttgaa gatgtggtcg cgatggcggt acattctgtc aaacgcgctc
    14281 gcaattatac tgacgacgtc gaattttcct gtgaagacgc gggccgcact ccgttagaca
    14341 atctgtgccg catcgtggaa gcggcgatca aagccggcgc gacgaccatc aatattcccg
    14401 ataccgttgg ctataccacg ccgtatcaat ttggtggcat catcaccaat ttgtacgagc
    14461 gagttccaaa catagataaa gccattatct ccgtacactg tcacgatgat ttagggatgt
    14521 cggtcgctaa ctctattact gccgtacaag cgggggctcg tcaggtcgaa gggacgatca
    14581 atggtatcgg tgaacgtgct ggaaactgtg cgttggaaga ggtcattatg gccatccgca
    14641 ctcgttccga aatgctgggc gtccacacca atattcatca tcaggaaatc tatcgtacta
    14701 gccaatttgt cagccaaatg tgcaatatgc ccatccctgg caacaaagcc atcgtcggtt
    14761 ctaacgcttt tgcccactca tcaggtattc accaagacgg cgtgctgaaa aaccgcgaaa
    14821 actacgaaat catgacgcca gaatcgattg gtctgaatca ggtacagctg aatctgacct
    14881 cacgatccgg acgcgccgcg gtgaagcatc atatggaaga gatgggatat cgcgaaggca
    14941 ccgacttcaa tctggatact ctgtatgacg ctttcctgaa gctggctgat aaaaaaggtc
    15001 aagttttcga ctacgactta gaagccttag ctttcatcaa taaacagcaa gaagagcctg
    15061 agcatttccg tttggactac ttcagcgtgc aatctggcac cagcgtaatg gctacagcct
    15121 cggtaaaact gaatatcgga ggagaaatta gcgccgaagc agcgaccggt aatggccctg
    15181 ttgatgcggt atatcaggct atcaaccgta tcgccggtta tgacattgat atcgtcaaat
    15241 atcagctgtc agccaaaggc caaggtaaag atgcgctggg tcaggtggat atcgtcgcta
    15301 attataatgg tcgtcgcttt cacggcgttg gcatcacaac ggacatcgtt gagtcatcag
    15361 ctctggcgtt aattaacgtt ctgaacaata tctggcgtgc acaacaggtg gaaaaagaaa
    15421 aacaacgcat ccaccagaca caaacaacat catcacattc taatcaggaa gccgtctaat
    15481 catgagcaaa acacatcaca tcgccgtttt acccggagac ggcatcggtc cagaaatcat
    15541 ggctcaggcc tacaaaacca tcgacgccgt acgtcagcgc tttggcctgc gtatctccac
    15601 cagcgaatat gacgttggtg gtgcggcaat cgacaagcat ggcacaccgc tgccggcggc
    15661 aaccatcgca ggctgcgaac aagccagcgc tattttgttt ggctccgtcg gtggccctaa
    15721 gtgggaaaat ctgccaccgg cgcagcagcc agaacgcgga gccttattgc cactgcgtaa
    15781 acacttcaag ctgtttagca atctgcgccc agcgcgttta tatgaaggtt tagaagaatt
    15841 ctgcccgctg cgcagcgata ttgccgcacg cggctttgat atcctgtgcg tgcgcgaatt
    15901 gaccggcggt atctacttcg gccaaccgaa aggccgtgaa ggtcagggaa tgcatgagcg
    15961 tgcgtttgat accgaggtat accaccgttt cgagattgaa cgcatcgcgc gtatcgcctt
    16021 cgaagctgcc cgtaagcgcc gtggaaaagt gacctcaatc gacaaagcta acgtattgca
    16081 aagttctatt ttgtggcgcg aaattgctac cgagattggc aaagactatc cagatgtcgc
    16141 gttaaatcac atgtacatcg acaacgccac catgcagttg atcaaagacc cttcgcagtt
    16201 tgacgtgatg ctgtgctcca atatctttgg cgatattctg tctgacgagt gcgccatgat
    16261 caccggctct atggggatgt tgccttccgc cagtttgaac gaacaaggct ttggcctgta
    16321 tgagcctgcg ggcggctctg cgccagacat cgcgggcaaa aacattgcca accctatcgc
    16381 acaaattctg tcattcgccc tgctgctgcg ttacagcctg gacgctgacg acgcggccaa
    16441 cgccgtagag caagcggtaa acaaagcatt agaacaaggc ttccgcactg gtgatttagc
    16501 cggtgatggt caggctattt caacctcaga aatgggtgat gtcatcgccc gctttatcgc
    16561 tcaggaggcc tgatcatggc gaaaacttta tatcagaaac tgtttgatgc acacgtggtt
    16621 tatgaagcta aaaacgaaac gccactgttg tatatcgacc gccacttggt gcatgaagtg
    16681 acttctccac aggcgtttga cggcctgcgc gcgatggggc gtccggtacg ccaaacaagt
    16741 aaaacctttg ccaccatgga tcacaacgta tcaacgcaga ctaaagacat taatgcctgc
    16801 ggcgatatgg cacgcatcca aatgcaagag ttgatgaaaa actgcaagga atttggggtt
    16861 caactgtatg atctgaatca tccattccaa ggcattgttc acgtcatcgg gccagaacag
    16921 ggaatgacgc tgccgggcaa tactatcgtc tgtggtgact ctcacacggc aactcacggt
    16981 gcatttggcg cattggcttt cggcattgga acctcagaag ttgaacatgt tttagccacg
    17041 caaaccttga aacaggggcg ggcgaagacc atgaaaattg aaattatcgg cgatgcggca
    17101 gaaggcatca cggccaaaga tatcgttttg gccgtgattg gaaaaatcgg tcacgcgggc
    17161 ggtaccggac atgttgtcga gttctgtggc aaagccgttg aagcactgtc aatggaagga
    17221 cggatgacgc tgtgtaatat ggccattgag atgggcgcta aagcgggtct ggttgcgcca
    17281 gatgaaacca cgttcaccta tctgaaaggg cgtcagtttg ccccacaggg tgataactgg
    17341 gaaaaagccg tcgagtactg gcgtacgttg aaatccgatg caggtgctca attcgacgcc
    17401 atcatcacgt tgaacgcagg cgagattgca ccgcaggtta cctggggaac caacccagga
    17461 caggtgattg cgattaatca gcctatccca acgcccgaat ccttcagcga tcctattgaa
    17521 cgcgcctcgg cggaaaaagc gctggcctac atggatttag cagcaggtgt taagttgacc
    17581 gacgtcgcga tcgacaaagt attcatcggc tcctgcacca actcacgcat tgaagattta
    17641 cgtgcggcag cggcaattgc caaaggccgt aaagtcgcca atggcgtaca agccatcgtc
    17701 gttcccggct cggggccagt aaaagcccaa gcggagtcag aaggtttaga caagattttc
    17761 atcgaagccg gtttcgaatg gcgtttgccg ggctgttcca tgtgcttggc gatgaataac
    17821 gaccgtctga atccgggtga acgttgtgca tctactagca accgtaactt tgagggacgt
    17881 cagggccgcg gtggtcgtac tcatttagtt agccctgcca tggccgcagc ggcagccgtg
    17941 agcggacact ttgccgatat tcgtgaatta gcgaccgcag cggtctaaca ggagcactct
    18001 tcatggctac atctactcag tctggtttaa ttaaacatag tgggatcgtg gttcctttag
    18061 acgccgccaa cgtcgatact gacgccatta ttcctaagca gtttttgcaa aaagtgactc
    18121 gcaccggctt tggtcaacac ctgtttaacg actggcgttt tctggatgat gcggggcagc
    18181 agccaaatcc tgacttcatt ctgaatcagc ccgaattcaa aggtgccagc attttgttga
    18241 cgcgcgaaaa cttcggctgc ggctcttctc gcgaacatgc gccatgggct ctgaccgact
    18301 acggctttaa agtggttatt gcgccgagtt ttgccgatat tttttacggt aactcgttca
    18361 ataaccagct gctgccggtc accttgagcg aagccgaaat agatgaactg ttcgcacagg
    18421 ttgaagccgc accggggatg agtttcaccg ttgatttaga aacacaaacc gtgcaagcgg
    18481 gagataaaag ctattcgttt gagctggata gtttccgccg ccactgcatg atgaatggtt
    18541 tagatagcat tggattgacg ttgcagcatg aggcggctat ttcagaatat gaggggaaat
    18601 taccggagtt tttgcgatag ggatgcattt accgcgccct gtgttcagac ggtgtaagtt
    18661 ttcgtacgcc tagagcactg aaatctacat gagcactgtg taaggtttcg tacgcctaga
    18721 gcaccgaaac ctacatgcac tccgtgcagg cgtccgagtc ggggggccag tcgctgcccc
    18781 ccgacacccc agcttggcac cgtccttcag cctgcttcgc aggtacccga atctcgtcat
    18841 tccggcttta acggaacgaa cggcaatcgc catcctggct cctccgttct ttcgccgacg
    18901 tcctgtcggc gaatcctagc cttcattcct ctcttcggcc gaagaacaac gtgccggaaa
    18961 aggtcaacgt caaaaccaaa aagacaaaag acaaaagaca aaatcaaaac ttttttaggt
    19021 ttttagttta agtcttggct gggagagccg gcacgacagg gatgtcgtga cggagtttgg
    19081 ggcgccctgg atgggcgata ccaaaccgga gcggagatgg cgtctcggat aaaagcgcgc
    19141 gagttgagag cccccgcgca acggggcttt catcggtcgc cttcgccagt aggctcatgg
    19201 aaacgcatgt gctgaccggc gaacgaaaca tttcactgta atcccataga ggattagcgt
    19261 tccaaaccgg agcggcgatg gcatctcaaa taacagcgtg caagtgcaga gaacaagtgg
    19321 acggaatctg gttcctatta ccaatacccc aaccacttcc accacaaact cccaatcacc
    19381 atccaaatca gcaggttaat tacactaaga acaaaaccgg ttttccacca ttcccccagc
    19441 gtcacatatc cagaaccaaa aataataggc gcagtccctg taccatagtg ggttaaggac
    19501 atcatcagcg aggaggaaaa tgctaatacc agacccagca gcgcaggcgg tgcgcccagc
    19561 gccaatcctg cggcaaagaa cgcggcgaac atagcggtga tgtgcgcagt ggtactggca
    19621 aagaaatagt gcgaatagac gtacaccaac gtcagcaaaa tcatcccgcc aatccagccc
    19681 atgccaagat gagaaatcgc accaccgacc gtttgggaga gccaactaat cagccctaat
    19741 tttcccagat aggtcgccat catcacaagc gcggcaaacc acactaccgt atcccaagca
    19801 cctttgtgct tgagcacgtc atcccaactc aaaacaccgc tggccaacag aatagacaat
    19861 ccgataaatg ctgcggtggt tggatttacc gtccagtcac tccccaatag gaaagccggg
    19921 attcctgccc acaggaagag caacagcgcg aataccccta gggtaatttt ttccgccagc
    19981 gaaattggcc ccagatcgcg cagtttatct ttggcaaatc gcggcgcatc aggcgtgctt
    20041 ttaatctccg gtggatacag ccagtaaaca attaacggca tcaccagcag agaaataatg
    20101 cccggtacca atgcagcaat tgcccacatc gaccatgtca gctcaaaggt cgaatccgtt
    20161 cctttcagta aaagattcac aattaacggg ttgggcgcag tcgcggtgat aaacatcgcc
    20221 gacgttacgg ggttgatgtt gtagttcact aacgataaat agcgaccaat tttctccgtt
    20281 gagcccggct ccggcttcga gccaaaacta tcggcaatcg acttcattat ggggtggatg
    20341 atccccccac cgcgcgcggt attacttggc gtaaccggcg ctaacgttgt ttcagcaagc
    20401 gccaacgcat aggcaatgcc cagcgttttt ttgccaaaca gcgaaataaa gtaataacca
    20461 atgcgtgccc ccagccccgt tttattgagg ctcagggaaa tcatgatgga aatcccgatc
    20521 agccaaatca gctgatttga aaaaccactg agcgcatcgt ccagcgcagc ggtgggctta
    20581 cccggattcg tgacttgtgt aacggccacc agcgcaatag caataatgga cacggcacca
    20641 atcggcatcg ctttaccaat aatggctgca atggtgccca cgaatagcgc aagcaagtgc
    20701 catgcatttg gactaacgcc ctcaggcaca gggatcacga accagataat caatgcgata
    20761 gcgatggaga tcagcgaagg tataggttta agcggtgtta atttacccat attgtcatca
    20821 actcttccaa agtgagtcgg tatctcaaag cgagacaggc aagcgtagtt aggttttgca
    20881 ccttacatca tacgttttat aggctcactg cgcacgggcc atgtgcatgc gattgggtgt
    20941 atgacagtgg tttatccaaa aatcagtaag cacagttatc ctcatctgcg cttactgctc
    21001 aacttaacaa ttaacctcct gaaacagcaa tcggttcaaa acatcatcac tacatgcaac
    21061 attgtctacc atttcacaac gagaaagatt gtcatccagc tcatattgaa tgaactcatg
    21121 gatcttcttc atccgaggcc catacttagc ttcgctggct tcacattttg catgcaataa
    21181 ttgcgctatt tcatccaata aatcagcgtc atcgacagta ccagccacta attgctcgaa
    21241 acgcataggc ggaacacctt tacctgcttc aatccaacgc accgccagca atggccgcaa
    21301 cacatagaag tattttttca agcgaacttc ttcaccttgc agatacccac gaaagttttt
    21361 ccgcgccatc gacaaatagt gataacgccc acgtaagcca gagaagtaat cgggcaacaa
    21421 tgctcttaat gcagcggtcg ccctttcctc attgcgataa acaatcgggg aatccagcca
    21481 ttccatcaac gttgggttcg agcgttttat caaccccaac gttttacgta gctcccagcc
    21541 acacacgtct aactcatcgt caattggcat ttctatcaca tcacgaccgg actcaactcg
    21601 cagataccat tctggtcgat gaacgtaaat aaagcgcaca tcataatcac tgtccgttga
    21661 agcaaatccc cagcctcggc tgcctgattc acaggcgtac aatatgcgta tctgatattc
    21721 ctcttccaac gcacacagcg tctgttgaat acgcatccgc attgcggcgc ttacgccgca
    21781 tgaagttctg agttccatag gtaacattac acccctttaa tttgtataag cccgtttagc
    21841 acctgatcta atccaccaaa cacggatatt ttatcgatac gctctgcgac tctttccaac
    21901 gtttctaact cttttaggcg cagcgccacg gggttgtttt ccatgacttt cgccgtattt
    21961 aataacgatc gcgtcgcaga ggtttcttca cgacggcgga tcacattagc ctgagccaat
    22021 ttttccgctt caaccacacg cgacaaaatg gttttcatat cacccggtaa aacaatgtct
    22081 ttaacaccta gcgatacgac ctcaatgcca tagccaacca gtttccgcga cacctgctca
    22141 ctcacgatgt cgtctataat ctgcttattc tccagcaact cgtctaatgt gcgtgtacca
    22201 acagcctcac gcagcgcgaa ctgcaactcg cgataaatgt gctccagcgg tttagcaacc
    22261 aaagcaaatg attgcagcac atcgctgtag cgccagttag cggctaagtt caaccgaaga
    22321 ttcactttgt cacgggtcaa tatctcttgc ccgctgactt ctaacacctg caaacgggta
    22381 tcaacaattt cggcttccac cgcatggttg aagcgccaat atccactaat accagggctt
    22441 aacaacgcct gtgttgcacc atcaattttt aatatgccga catgccacgc tggcacctgc
    22501 accaataaca ccccttctcc acctttaatc gtacggttgc gtaatttcgg ttgatgcagc
    22561 gcagccacaa tctctgacgg tacttctaca ttattagcct caattcgttc gatgcgttgc
    22621 tgattgccat tcaaccaata aagacgacgc gtccccggtg gcaatatttc ctgtaaaatg
    22681 tcattttcat agcgcaggcc gatctcttgt tcagataaat ccaccgcggt gcaatagcgt
    22741 tcaacccact caggctggta gctgcgtaaa tgttcggcca gtgcgggctc cactctgcta
    22801 tcgctaagat taaccaccgt cactgccaac tgattagtcc agtcaaaaaa gcgatattct
    22861 cccgcttcga gtactttctg ataatcgcct ttcttcgtca gtaaaccgat ctgccctttt
    22921 tgtataatga tgttcttacg catatttttt cttccttgtg attaattagc ccgctgtctt
    22981 agaaaacggg cagtgacgcg aagcgggtgg ggagaactct ctagccgata ctcgcgctaa
    23041 cgagaccttg ccacctgccc agcgtgttag ctggttttct acgacggtaa ccattaacgg
    23101 cttggctaca cgggctggca ctacaataaa tttctaaatt tcctacccat caggaatatt
    23161 tgatgttctg ggattcgaac ccaggttaac caggccatct accgctggca gaacacatcg
    23221 cagataacgc aacttggcgt tcttgatgtg ccggtgggag tttagaatcc ctacgacccc
    23281 agcaagtggc gttataaata ttgccaaaag cgtgccattt tttaaaaaca gcaaaataaa
    23341 aaattaatca catgaaaaat aagatattta tttttattac ttgcgatatc accttgaatc
    23401 aaatacgtgt aaagttatct taaaatatcg tcatttataa ttttggataa gaagatgaag
    23461 cgcagagtcg ttattggtgt gctgggcact gttctggata agcgcggtaa acgagcaaat
    23521 cgttggaata aatggcgacc gacggtagga ctatgccaac agcctgattt gcccattgac
    23581 cggctcgaac ttctgtatca gccaagagat ctcggcatgg cgcagcaggt aagcgatgat
    23641 attgcccagc tcggcagcac tcaggtttgc ctgcatcaag ttaatctgca cgacccgtgg
    23701 gattttgaag aggtttatac tgcatttctc gactttgcca cccattaccc tttcgatacc
    23761 gataacgaag agtatttaat ccacatcacc accggcaccc atgtggtaca aatttgctgg
    23821 ttcctgctcg cggaggcccg ctatttccca gccagcctgc tacaaacctc gccagcgcct
    23881 aaaagccaag agaaaaccga ggccactccc gccggtgttt actccattat cgatcttgac
    23941 cttagtcgct atagcaaatt aacccgtcgc ttccagcgcg agcagcaggc ttcaatttca
    24001 tttttgaaat cgggaattgc cactcgtaat accaccttca atacgctgat tgatcagatt
    24061 gaacgcgttg ccttacgttc gacggcacct attctgctga ctggccccac cggggcgggt
    24121 aagtcatttt tggcacagcg tatttaccag ctgaggcaat cacggcacaa agttagcgga
    24181 cgatttgtgg ccgtaaactg tgcgacgcta cgcggggaca acgcgatgtc gaccttgttt
    24241 ggtcacatca aaggggcatt taccggtgcg ctacaggcgc gtagcggcct gctgcgagaa
    24301 gccgacggcg gcgtgctgtt tttggacgaa atcggagagt taggactcga tgaacaggcc
    24361 atgctgctca aagcaatcga agaaaaaagg tttttacctt ttggctcaga taaagaggtt
    24421 tccagcaatt ttcaactcat tgcaggcacc catcgcgata tgcggcaatg ggtcaagcaa
    24481 ggacgttttc gcgaggattt atatgcgcgc atcaatatgt ggacttttcc tctccccagc
    24541 ttggcgcagc ggcgagaaga tatagagccg aatctggatt ttgaactcaa ccgctatagc
    24601 caagaacagc aagcacaggt gcgtttcaat aaagaagcac gtcaacgcta tctgcaattt
    24661 gcctgttccg agcaggctga atggcgagga aacttccgtg aactagcggc ttcggtcacc
    24721 cgtatggcaa cacttgcgga tacagggcgt attgatgacg aactggtaca agaagaaatc
    24781 gctcggctac aacaaaactg gcaaaaagat cagccagaaa ttttacccga tctccccgag
    24841 ttagatctgt tcgatcgcag ccaattagcc agcgtgatca gcgtttgccg ctcgtcagac
    24901 agcttatccg aggcaggacg taagctattc tccgtatcac gccaattgaa aaaacagccc
    24961 aatgacgccg atcgtctacg taaatatctg gcacgttttg ggctgagctg ggagagtatc
    25021 aaaggagaat aaattcccta gggcacatct cgcactcgcg agcacaaaat caaggccact
    25081 atcgccagcg ctgtcgctag ccaatatacc gcgtagtggc ctaatgtttc agccaacgcg
    25141 ccttgtaata cccctgccat aatcacaccg gtcgaaatac tgttggtgaa tagcgtcgtc
    25201 gcactgcccg ctcgacccgg cattaaatct tgaaaataga gcatgccgat accggcaata
    25261 attccgatga acaccgcgtt aaacaactgc aacaccatca atgccaattt gaatttaaac
    25321 aacaccaaac cggcataaaa taagatccca gcggcaacgg caaacagcat catgttacgt
    25381 ttgccaaaac gtttaacgta gtaacccgct agaatcatcg cgggaatctc taaacccgca
    25441 gcagtcccca tcaagagccc tgccaaattt tctggcaga
//
