LOCUS       NZ_CP022930.1          20603 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP022930.1 Enterococcus durans strain BDGP3 chromosome, complete
            genome.
ACCESSION   NZ_CP022930
VERSION     NZ_CP022930.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:50:38
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 671576
            Orig. end    :: 692179
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20603
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[681576:682179](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10603
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20603
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20603
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="2"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(4449..4805)
                     /locus_tag="ctg1_623"
                     /transl_table=11
                     /translation="MKVKIYGSLHCVTCLKAKNWLESNQLTYQFIDLEQQELTMTEAEE
                     LCNFDEMHTEQLFVTWSEAFKDIQVDLTSISKKQLALLCKQYKELLRRPLIIIDEVLFV
                     GYNEQLMEQLILSE"
     PFAM_domain     complement(4473..4790)
                     /aSDomain="ArsC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03960.17"
                     /description="ArsC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_623_0014"
                     /evalue="2.50E-07"
                     /label="ctg1_623"
                     /locus_tag="ctg1_623"
                     /protein_end="111"
                     /protein_start="5"
                     /score="30.8"
                     /tool="antismash"
                     /translation="YGSLHCVTCLKAKNWLESNQLTYQFIDLEQQELTMTEAEELCNFD
                     EMHTEQLFVTWSEAFKDIQVDLTSISKKQLALLCKQYKELLRRPLIIIDEVLFVGYNEQ
                     LM"
     CDS             complement(4826..5173)
                     /locus_tag="ctg1_624"
                     /transl_table=11
                     /translation="LQANRLDFEEKNIFADPITESEIREILAATEGGVEDIISTRSKIY
                     EKLAIDFNELSLKQMIVLFKEYPSLLRRPILIDEKRILIGFNEDEIRSFVPREIRSVAR
                     NLIYMQNSIFS"
     aSDomain        complement(4889..5173)
                     /aSDomain="TIGR01617"
                     /aSTool="tigrfam"
                     /description="arsC_related: transcriptional regulator,
                     Spx/MgsR family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_624_0006"
                     /evalue="2.60E-25"
                     /identifier="TIGR01617"
                     /label="ctg1_624"
                     /locus_tag="ctg1_624"
                     /protein_end="95"
                     /protein_start="0"
                     /score="86.9"
                     /tool="antismash"
                     /translation="LQANRLDFEEKNIFADPITESEIREILAATEGGVEDIISTRSKIY
                     EKLAIDFNELSLKQMIVLFKEYPSLLRRPILIDEKRILIGFNEDEIRSFV"
     PFAM_domain     complement(4892..5068)
                     /aSDomain="ArsC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03960.17"
                     /description="ArsC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_624_0015"
                     /evalue="3.40E-19"
                     /label="ctg1_624"
                     /locus_tag="ctg1_624"
                     /protein_end="94"
                     /protein_start="35"
                     /score="68.8"
                     /tool="antismash"
                     /translation="DIISTRSKIYEKLAIDFNELSLKQMIVLFKEYPSLLRRPILIDEK
                     RILIGFNEDEIRSF"
     CDS             complement(5451..7664)
                     /locus_tag="ctg1_625"
                     /transl_table=11
                     /translation="MGKAINQGNEKEILRLQRELKHWEKKYSKLQQIFRMQEEIIASYE
                     AAYGEAPGLIDEEKEDNGSHSFFDMMEKRSYNRFNQEQKAAITYNMEKNLRIIAGAGSG
                     KTQTICAKAVYLMTQEQVEEQRILMITFTRNAANELKKRVDNFSQRKTNVHIGTFHSIF
                     FRLYNDIQRRFPEITATGIQGEFSKDTSYKINGILQQLIRKYNLYAFDQSGEKTISARL
                     DYWQNMNLSIEEIVEVIQDKFDSLEQKATKPISERMKYLMSELQKQKKEQKLFEFNDVL
                     QNLKSALQDEAVRRYVGEKYDYLFIDEFQDTNPLQWEIVRLITKDSHIKLIVVGDDDQS
                     IYGFRGSEPSYIKNFDQEYPAKTLFLLTNYRSRAAIVQGANRLITFNKNDRIPKAMVPA
                     QKEAGIMSALSFENTQTESKWIIKQIQSFIKSNGKYKESIVLYRSLSQTQQLVQDLLQT
                     EIPFVLEADGQYEGVFGIRTFQQFYQKLVLWHEAPTQQKKNHAYKQLLHQLMMNCYLKR
                     AECDFFFSNENKKKDIINYLLAVRPNMKSKEKELRSFIGEINALEKNENYKIESLIKGF
                     LKLLKPAKEMDGTEKEWLSETIKKYPTLTQLMGLEKEIQVLAKQLKIRLTAYRQGKLDA
                     LCIQSIHRSKGLSYRNVFLIGCNEGLIPYNGATEKNALSNKQIKAEHLTTIEEERRLFY
                     VAMTRARNRLYLCIPLMKGTRRLKPSRFIRETGCKIKKQSIYN"
     PFAM_domain     complement(5547..6185)
                     /aSDomain="UvrD_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13361.8"
                     /description="UvrD-like helicase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_625_0018"
                     /evalue="8.30E-21"
                     /label="ctg1_625"
                     /locus_tag="ctg1_625"
                     /protein_end="706"
                     /protein_start="493"
                     /score="74.9"
                     /tool="antismash"
                     /translation="TQQKKNHAYKQLLHQLMMNCYLKRAECDFFFSNENKKKDIINYLL
                     AVRPNMKSKEKELRSFIGEINALEKNENYKIESLIKGFLKLLKPAKEMDGTEKEWLSET
                     IKKYPTLTQLMGLEKEIQVLAKQLKIRLTAYRQGKLDALCIQSIHRSKGLSYRNVFLIG
                     CNEGLIPYNGATEKNALSNKQIKAEHLTTIEEERRLFYVAMTRARNRLYL"
     PFAM_domain     complement(6273..6569)
                     /aSDomain="UvrD_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13361.8"
                     /description="UvrD-like helicase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_625_0017"
                     /evalue="1.30E-11"
                     /label="ctg1_625"
                     /locus_tag="ctg1_625"
                     /protein_end="464"
                     /protein_start="365"
                     /score="44.7"
                     /tool="antismash"
                     /translation="LLTNYRSRAAIVQGANRLITFNKNDRIPKAMVPAQKEAGIMSALS
                     FENTQTESKWIIKQIQSFIKSNGKYKESIVLYRSLSQTQQLVQDLLQTEIPFVL"
     PFAM_domain     complement(6588..7427)
                     /aSDomain="UvrD-helicase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00580.23"
                     /description="UvrD/REP helicase N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_625_0016"
                     /evalue="2.30E-51"
                     /label="ctg1_625"
                     /locus_tag="ctg1_625"
                     /protein_end="359"
                     /protein_start="79"
                     /score="175.3"
                     /tool="antismash"
                     /translation="NQEQKAAITYNMEKNLRIIAGAGSGKTQTICAKAVYLMTQEQVEE
                     QRILMITFTRNAANELKKRVDNFSQRKTNVHIGTFHSIFFRLYNDIQRRFPEITATGIQ
                     GEFSKDTSYKINGILQQLIRKYNLYAFDQSGEKTISARLDYWQNMNLSIEEIVEVIQDK
                     FDSLEQKATKPISERMKYLMSELQKQKKEQKLFEFNDVLQNLKSALQDEAVRRYVGEKY
                     DYLFIDEFQDTNPLQWEIVRLITKDSHIKLIVVGDDDQSIYGFRGSEPSYIKNFDQEY"
     CDS             7843..8532
                     /locus_tag="ctg1_626"
                     /transl_table=11
                     /translation="MNTSFHEGRTIGLLLTFIGGAMDSYTYIQYNAFASAQTGNIVLAI
                     IQSFDGEWLSVGKKVLSTLFFFLGILLTKFLINYFQKKEKHFWRLFVLYYEAVIFFLVS
                     LPSINAHPALVTIMIAFTAAIQWLAFDKIDGRAYTNLFTTGNLKGVATNLYDYWVTREK
                     AEFDRFIHFLTVVLAFIAGAIVQVFFHHLFNTFSILLVSVLFLIIAITQSVQLWHFYRQ
                     NPFIVKK"
     PFAM_domain     7876..8472
                     /aSDomain="DUF1275"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06912.13"
                     /description="Protein of unknown function (DUF1275)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_626_0019"
                     /evalue="1.30E-33"
                     /label="ctg1_626"
                     /locus_tag="ctg1_626"
                     /protein_end="210"
                     /protein_start="11"
                     /score="116.6"
                     /tool="antismash"
                     /translation="GLLLTFIGGAMDSYTYIQYNAFASAQTGNIVLAIIQSFDGEWLSV
                     GKKVLSTLFFFLGILLTKFLINYFQKKEKHFWRLFVLYYEAVIFFLVSLPSINAHPALV
                     TIMIAFTAAIQWLAFDKIDGRAYTNLFTTGNLKGVATNLYDYWVTREKAEFDRFIHFLT
                     VVLAFIAGAIVQVFFHHLFNTFSILLVSVLFLIIAI"
     CDS             complement(8599..9300)
                     /locus_tag="ctg1_627"
                     /transl_table=11
                     /translation="MIIVAGTIGAGKSTLTEMLARNLETKPFYENVEDNEVLPLFYSNP
                     DKYAFLLQIFFLNKRFMAIKDAFSHDDNVLDRSIYEDSLLFHLNADLGRVSQEEVAQYQ
                     GLLETVLKELEAVAPPKKPDLLVYIRVSFETMLARIKKRGRIYEQLEQDPELYAYYQEL
                     NRRYEEWYESFDICPKMVIDGDKYDFVEDPSAGEEIVRLINPHTKKIEERALEMPARYT
                     TDREKVKGIFS"
     PFAM_domain     complement(8686..9297)
                     /aSDomain="dNK"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01712.21"
                     /description="Deoxynucleoside kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_627_0020"
                     /evalue="1.40E-55"
                     /label="ctg1_627"
                     /locus_tag="ctg1_627"
                     /protein_end="205"
                     /protein_start="1"
                     /score="188.4"
                     /tool="antismash"
                     /translation="IIVAGTIGAGKSTLTEMLARNLETKPFYENVEDNEVLPLFYSNPD
                     KYAFLLQIFFLNKRFMAIKDAFSHDDNVLDRSIYEDSLLFHLNADLGRVSQEEVAQYQG
                     LLETVLKELEAVAPPKKPDLLVYIRVSFETMLARIKKRGRIYEQLEQDPELYAYYQELN
                     RRYEEWYESFDICPKMVIDGDKYDFVEDPSAGEEIVRLINP"
     CDS             complement(9536..9742)
                     /locus_tag="ctg1_628"
                     /transl_table=11
                     /translation="MENEQLFEVGEAYAFKSDLFGAPVKGEIEKVYENSVMIRVINCAT
                     EDNDTAHNLQWQLVVRKSSAVTE"
     CDS             10001..10603
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_629"
                     /sec_met_domain="AgrB (E-value: 1.2e-27, bitscore: 93.8,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNKVVNKLLETLFSGEKTEEDMVYIQVKFALEVLMNNLGKLAVV
                     LVFALATGSWSETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLLMKHFELT
                     VSFPWMVFLLVSCFLLLLRYGSRGTAINPIEPEKRPPLLKKAIFMFVVFTLLILFFANS
                     YFSTYLLLGIVLEIATLLPITNYLMNLGGIFYEKNNH"
     PFAM_domain     10010..10537
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_629_0021"
                     /evalue="9.40E-27"
                     /label="ctg1_629"
                     /locus_tag="ctg1_629"
                     /protein_end="179"
                     /protein_start="3"
                     /score="93.6"
                     /tool="antismash"
                     /translation="KVVNKLLETLFSGEKTEEDMVYIQVKFALEVLMNNLGKLAVVLVF
                     ALATGSWSETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLLMKHFELTVSF
                     PWMVFLLVSCFLLLLRYGSRGTAINPIEPEKRPPLLKKAIFMFVVFTLLILFFANSYFS
                     TYLLLGIVLEIAT"
     CDS             10744..12021
                     /locus_tag="ctg1_630"
                     /transl_table=11
                     /translation="MFLWSIALQYLIYTICILLIEHQIKNKIFFAGVILLSCFLLGFIY
                     PILGIFTALFAIGMLMLTFFFFTSSPQRLIYALPWGLLTSLLGDHLASISDFLVLESAV
                     IEPGDSLQYFHIVVSAVLAALLAFGFKKALERFYGLDRRMIGIIGTLILFTYYIIIFYT
                     RFSGETPEVLALNTSFFIFYLCFGVIILVYYWKISNKKMADQLLEQRIQLQQDYIKDLE
                     KNYQDLREFKHDYQNLLFSMNSYLEEGDLDGLRKYYDQNILPTRQMMQLFPANLSLLDN
                     MKNRDIRSLLSLKLMMAQEKGLSVQLVFPDEIKLDKKHTVNLVRMLGIILDNAIEGASI
                     TKKKKIELIVLKKNNSVIIRVINTTLNTLPLNKLKQQGFSTKSNPKNEGLGLFILDELT
                     KLNPYIFLETSIENQRFSQTIYIQMK"
     PFAM_domain     11701..12012
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_630_0022"
                     /evalue="8.00E-18"
                     /label="ctg1_630"
                     /locus_tag="ctg1_630"
                     /protein_end="423"
                     /protein_start="319"
                     /score="64.3"
                     /tool="antismash"
                     /translation="TVNLVRMLGIILDNAIEGASITKKKKIELIVLKKNNSVIIRVINT
                     TLNTLPLNKLKQQGFSTKSNPKNEGLGLFILDELTKLNPYIFLETSIENQRFSQTIYIQ
                     "
     CDS             12034..12762
                     /locus_tag="ctg1_631"
                     /transl_table=11
                     /translation="MIPIYICEDDMKQLEVISAVIKNRIMIENLDSYVHVATSDPMELL
                     QAARVRTSSFGIYFLDIELKDSELDGIMIGKHIRDLDPLGKIIYVTSHTDLSMTILKSN
                     IEPTDYIIKEDVFDLKENVERILSKIFEDVQTTPLQKDIFKIEFNDEIKFLPIKDIQYF
                     STSPGTPHKLEVHLTHAQMQFYDKIKEIEKMNQHFIRCHKSYVINTQNVRTINKKTREI
                     TLANGEMIPASVRGLKKLIS"
     PFAM_domain     12043..12396
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_631_0023"
                     /evalue="7.50E-10"
                     /label="ctg1_631"
                     /locus_tag="ctg1_631"
                     /protein_end="121"
                     /protein_start="3"
                     /score="39.1"
                     /tool="antismash"
                     /translation="IYICEDDMKQLEVISAVIKNRIMIENLDSYVHVATSDPMELLQAA
                     RVRTSSFGIYFLDIELKDSELDGIMIGKHIRDLDPLGKIIYVTSHTDLSMTILKSNIEP
                     TDYIIKEDVFDLKE"
     PFAM_domain     12484..12753
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_631_0024"
                     /evalue="1.00E-19"
                     /label="ctg1_631"
                     /locus_tag="ctg1_631"
                     /protein_end="240"
                     /protein_start="150"
                     /score="70.6"
                     /tool="antismash"
                     /translation="EIKFLPIKDIQYFSTSPGTPHKLEVHLTHAQMQFYDKIKEIEKMN
                     QHFIRCHKSYVINTQNVRTINKKTREITLANGEMIPASVRGLKKL"
     CDS             13207..13485
                     /locus_tag="ctg1_632"
                     /transl_table=11
                     /translation="LETSKFAIGIHVFSTLTNFGVSALVTFIAGIFGIATAEARLLLDY
                     MDAKGLFTGSAVAAALDTSGNGWIGLYIRDVWNVSKAVDIGTQYKTM"
     CDS             13495..13848
                     /locus_tag="ctg1_633"
                     /transl_table=11
                     /translation="MKKADAKSIISIFVGVFLLMGVIEFIFKRNHSFILSNHYFEFLLG
                     FIVMNAFPIGRGWAKVRYFTLVFLSFYLPIKIGDLLSVEGLNITLGTYLIVLGIFLLIV
                     GPFFYRRIAHRVK"
     CDS             14324..14653
                     /locus_tag="ctg1_634"
                     /transl_table=11
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEPQ
                     KEFFDFSEDILSDIIAEGYDKDKILVEFKNRKNKMVSSFSNIATDTLTNSKAMTKEELA
                     KEIGL"
     CDS             14643..14933
                     /locus_tag="ctg1_635"
                     /transl_table=11
                     /translation="LGYEIVPSKHVIKYLKKIKEKPLKEKFLIIIYDEIAINPYSGSQK
                     TRDLSGIWSRGFTYAGTTYRIAYEIEENMVIPVLLCGTHENFYEQLKNIKG"
     PFAM_domain     14658..14918
                     /aSDomain="ParE-like_toxin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF15781.7"
                     /description="ParE-like toxin of type II bacterial
                     toxin-antitoxin system"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_635_0025"
                     /evalue="1.30E-25"
                     /label="ctg1_635"
                     /locus_tag="ctg1_635"
                     /protein_end="92"
                     /protein_start="5"
                     /score="89.3"
                     /tool="antismash"
                     /translation="VPSKHVIKYLKKIKEKPLKEKFLIIIYDEIAINPYSGSQKTRDLS
                     GIWSRGFTYAGTTYRIAYEIEENMVIPVLLCGTHENFYEQLK"
     CDS             complement(15301..16812)
                     /gene_functions="transport (smcogs) SMCOG1252:cation ABC
                     transporter, periplasmic (Score: 233.7; E-value: 4.4e-71)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_636"
                     /transl_table=11
                     /translation="MRRLIGLLSGVLLVGLLASCGSNQEAGKNEELQVLTTFYPMYEFT
                     KEIVGEEGNVELLIPAGTDSHDYEPSAKDMTKIQNADIFVYNDENMETWVPAIQETLRE
                     GKVLSIKATEGMLLLSGSEDGHDHTHEGEGHTHELDPHVWLAPSLAVKQVQTIRNQLIK
                     QYPEKEEVFTSNAENYLTKLQNLHQKYQDTLGQAKQKSFVTQHAAFNYLALEYGLKQVA
                     VTGLSSSEEPSVSRIAELKEFVTEHGISTIYFEENTKGSIAKTLANEAGVSLEVLNPLE
                     GLTKEQMAQGENYLSIMEKNLRALQKTTEIENPLEDRWEQEEKTVYNGYFEDSAVKDRT
                     LLDWNGAWQTVDSYLENGTLDPVFEYKAKVNPEKTAKEYKEYYKVGYHTDVAKITIKGN
                     ELTFTFKNGEVKKAEYRYSGKKVLDYQAGNRGVRYLFEAKEPQNSAYRYVQFSDHSIEP
                     SDSEHFHIYLGNESQEKLLEEMENWPTFYPAQMNGQEIAQEMMLH"
     PFAM_domain     complement(15304..15846)
                     /aSDomain="ZinT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09223.13"
                     /description="ZinT (YodA) periplasmic lipocalin-like
                     zinc-recruitment"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_636_0027"
                     /evalue="5.20E-82"
                     /label="ctg1_636"
                     /locus_tag="ctg1_636"
                     /protein_end="503"
                     /protein_start="322"
                     /score="274.2"
                     /tool="antismash"
                     /translation="EKTVYNGYFEDSAVKDRTLLDWNGAWQTVDSYLENGTLDPVFEYK
                     AKVNPEKTAKEYKEYYKVGYHTDVAKITIKGNELTFTFKNGEVKKAEYRYSGKKVLDYQ
                     AGNRGVRYLFEAKEPQNSAYRYVQFSDHSIEPSDSEHFHIYLGNESQEKLLEEMENWPT
                     FYPAQMNGQEIAQEMMLH"
     PFAM_domain     complement(15892..16713)
                     /aSDomain="ZnuA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01297.19"
                     /description="Zinc-uptake complex component A periplasmic"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_636_0026"
                     /evalue="2.20E-72"
                     /label="ctg1_636"
                     /locus_tag="ctg1_636"
                     /protein_end="307"
                     /protein_start="33"
                     /score="243.7"
                     /tool="antismash"
                     /translation="VLTTFYPMYEFTKEIVGEEGNVELLIPAGTDSHDYEPSAKDMTKI
                     QNADIFVYNDENMETWVPAIQETLREGKVLSIKATEGMLLLSGSEDGHDHTHEGEGHTH
                     ELDPHVWLAPSLAVKQVQTIRNQLIKQYPEKEEVFTSNAENYLTKLQNLHQKYQDTLGQ
                     AKQKSFVTQHAAFNYLALEYGLKQVAVTGLSSSEEPSVSRIAELKEFVTEHGISTIYFE
                     ENTKGSIAKTLANEAGVSLEVLNPLEGLTKEQMAQGENYLSIMEKNLRALQK"
     CDS             17096..18283
                     /locus_tag="ctg1_637"
                     /transl_table=11
                     /translation="VENKSKENSRFIRFLGGKTSYYVLGLLIMLALVIYIFQKVGFVFK
                     PFIVIFATALPPVLFALILYYLLDPLIKRLNKKLSRNLSVVIVYIVILMLIGLGSIWLI
                     PFLQQQAKTLIASFPDLFADFQQTLKQFLAQTPFSDAFNQFFSSIDDLTSNFTSFIGDY
                     WESGAKSLGNIFSAVTTTFITLFTGPIIAFFLLKDPHKFYQSVLGIVPPKFRTDFQTLT
                     KIANQQLGAFLKGQIIASFILGAVYWVTFLLIGLEFASILAIAAGILCIIPYIGPFIAF
                     FPGLFIAFQDSTFMAIKFILVWFIVQLLHGDLVVPRVMGNRLQIHPITILIVLLVMGDL
                     LGLMGVIFGIPIYTLIKLLVVFTFRKFKQRYNKFYGDQGVYQKADFSEKDYLDKE"
     PFAM_domain     17189..18172
                     /aSDomain="AI-2E_transport"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01594.18"
                     /description="AI-2E family transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_637_0028"
                     /evalue="7.50E-66"
                     /label="ctg1_637"
                     /locus_tag="ctg1_637"
                     /protein_end="359"
                     /protein_start="31"
                     /score="222.6"
                     /tool="antismash"
                     /translation="LVIYIFQKVGFVFKPFIVIFATALPPVLFALILYYLLDPLIKRLN
                     KKLSRNLSVVIVYIVILMLIGLGSIWLIPFLQQQAKTLIASFPDLFADFQQTLKQFLAQ
                     TPFSDAFNQFFSSIDDLTSNFTSFIGDYWESGAKSLGNIFSAVTTTFITLFTGPIIAFF
                     LLKDPHKFYQSVLGIVPPKFRTDFQTLTKIANQQLGAFLKGQIIASFILGAVYWVTFLL
                     IGLEFASILAIAAGILCIIPYIGPFIAFFPGLFIAFQDSTFMAIKFILVWFIVQLLHGD
                     LVVPRVMGNRLQIHPITILIVLLVMGDLLGLMGVIFGIPIYTLIKLL"
     CDS             complement(18534..20162)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257:Alpha-glucosidase (Score: 468.8; E-value:
                     4.2e-142)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_638"
                     /sec_met_domain="Alpha-amylase (E-value: 2.4e-91, bitscore:
                     304.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFKDKVIYQIYPKSYRDSNGDGIGDLAGIKEKLPYLHELGIDMI
                     WLNPIYPSPQKDNGYDISNYIAIDPLFGTMEEFESLVAEAKSYQIEIMLDMVLNHVSIE
                     HEWFQKALADDPFYQDFFILRDEPTDWISKFGGNAWAPFGDTGKYYLHLYDKTQADLNW
                     RNEAVQEELFKVVRFWMSKGVKGFRFDVINVIGKDEVLKNNSENQGKPEYTDKPITHTY
                     LQRLNKETFGQDAEIITVGEMSSTTVENCILYTEPSRNELSMVFNFHHLKVDYENGDKW
                     TTPPFDFEELKRLFHTWGEEMSAGNGWNALFLNNHDQPRALNRFVAVDSYRKQGAEMLA
                     TMIHLNRGTPYIYMGEEIGMIDPDFDSIADYVDIECLNAYHLLLEKGLSKKEAFRRIKA
                     KSRDNSRTPMQWTADENAGFTLGKPWLKVAESYGDINVEKELASPQSIFNYYQKLIRLR
                     KQYPVIALGSYQAYQPEHPQVYSFLRQYEEKKVIVFTNFYGKETTISLPEEFLDSKILI
                     DNYDGTIVERELKLKPYQAIALLKE"
     aSDomain        complement(18546..20156)
                     /aSDomain="TIGR02403"
                     /aSTool="tigrfam"
                     /description="trehalose_treC: alpha,alpha-phosphotrehalase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_638_0007"
                     /evalue="1.10E-256"
                     /identifier="TIGR02403"
                     /label="ctg1_638"
                     /locus_tag="ctg1_638"
                     /protein_end="539"
                     /protein_start="2"
                     /score="850.7"
                     /tool="antismash"
                     /translation="FKDKVIYQIYPKSYRDSNGDGIGDLAGIKEKLPYLHELGIDMIWL
                     NPIYPSPQKDNGYDISNYIAIDPLFGTMEEFESLVAEAKSYQIEIMLDMVLNHVSIEHE
                     WFQKALADDPFYQDFFILRDEPTDWISKFGGNAWAPFGDTGKYYLHLYDKTQADLNWRN
                     EAVQEELFKVVRFWMSKGVKGFRFDVINVIGKDEVLKNNSENQGKPEYTDKPITHTYLQ
                     RLNKETFGQDAEIITVGEMSSTTVENCILYTEPSRNELSMVFNFHHLKVDYENGDKWTT
                     PPFDFEELKRLFHTWGEEMSAGNGWNALFLNNHDQPRALNRFVAVDSYRKQGAEMLATM
                     IHLNRGTPYIYMGEEIGMIDPDFDSIADYVDIECLNAYHLLLEKGLSKKEAFRRIKAKS
                     RDNSRTPMQWTADENAGFTLGKPWLKVAESYGDINVEKELASPQSIFNYYQKLIRLRKQ
                     YPVIALGSYQAYQPEHPQVYSFLRQYEEKKVIVFTNFYGKETTISLPEEFLDSKILIDN
                     YDGTIVERELKLKPYQAIAL"
     PFAM_domain     complement(18621..18764)
                     /aSDomain="Malt_amylase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16657.7"
                     /description="Maltogenic Amylase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_638_0030"
                     /evalue="5.30E-07"
                     /label="ctg1_638"
                     /locus_tag="ctg1_638"
                     /protein_end="514"
                     /protein_start="466"
                     /score="29.7"
                     /tool="antismash"
                     /translation="GSYQAYQPEHPQVYSFLRQYEEKKVIVFTNFYGKETTISLPEEFL
                     DSK"
     PFAM_domain     complement(19074..20090)
                     /aSDomain="Alpha-amylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00128.26"
                     /description="Alpha amylase, catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_638_0029"
                     /evalue="7.10E-105"
                     /label="ctg1_638"
                     /locus_tag="ctg1_638"
                     /protein_end="363"
                     /protein_start="24"
                     /score="351.4"
                     /tool="antismash"
                     /translation="GDLAGIKEKLPYLHELGIDMIWLNPIYPSPQKDNGYDISNYIAID
                     PLFGTMEEFESLVAEAKSYQIEIMLDMVLNHVSIEHEWFQKALADDPFYQDFFILRDEP
                     TDWISKFGGNAWAPFGDTGKYYLHLYDKTQADLNWRNEAVQEELFKVVRFWMSKGVKGF
                     RFDVINVIGKDEVLKNNSENQGKPEYTDKPITHTYLQRLNKETFGQDAEIITVGEMSST
                     TVENCILYTEPSRNELSMVFNFHHLKVDYENGDKWTTPPFDFEELKRLFHTWGEEMSAG
                     NGWNALFLNNHDQPRALNRFVAVDSYRKQGAEMLATMIHLNRGTPYIYMGEEIGMIDP"
ORIGIN
        1 gacagtgccc aaatcgttac gcctttcgtg cgggtcggaa cttacccgac aaggaatttc
       61 gctaccttag gaccgttata gttacggccg ccgtttactg gggcttcaat tcgtaccttc
      121 gcttacgcta agcactcctc ttaaccttcc agcaccgggc aggcgtcagc ccctatactt
      181 catcttacga ttttgcagag acctgtgttt ttgataaaca gtcgcttggg cctattcact
      241 gcggctgatc gaagatcagc accccttctc ccgaagttac ggggtcattt tgccgagttc
      301 cttaacgaga gttctctcgc tcaccttagg attctctcct cgactacctg tgtcggtttg
      361 cggtacgggt cattgttttc tcactagaag cttttcttgg cagtgtgaca tcaggaactt
      421 cggtactatt atttccctcc ccatcacagc ttatccgtgt agacagaagc atttgactcc
      481 tatcaagact tactgcttgg acagacattt ccgatcgtct gcattcctta gcctcctgcg
      541 tccctccatt gctcaaacaa aaacaacgag tacaggaata tcaacctgtt gtccatcgcc
      601 tacgcctgtc ggcctcggct taggtcccga ctaaccctgg gcggacgagc cttccccagg
      661 aaaccttagt cattcggtgg acaggattct cacctgtctt tcgctactca taccggcatt
      721 ctcacttcta agcgctccag cagtcctcac gatctgcctt caacgccctt agaacgctct
      781 cctaccaata cacctaatgg tgtactccac agcttcggta atatgtttag ccccggtaca
      841 ttttcggcgc agggtcactc gactagtgag ctattacgca ctctttaaat ggtggctgct
      901 tctgagccaa catcctagtt gtctgtgcaa ccccacatcc ttttccactt aacatatatt
      961 ttgggacctt agctggtggt ctgggctgtt tccctttcga ctatggatct tatcactcac
     1021 agtctgactc ccggatatga atgaatggca ttcggagttt atctgaattc ggtaacccga
     1081 gatgggcccc tagtccaaac agtgctctac ctccatcatt ctcaaatccg aggctagccc
     1141 taaagctatt tcggagagaa ccagctatct ccaagttcgt ttggaatttc tccgctaccc
     1201 acacctcatc cccgcacttt tcaacgtacg tgggttcggt cctccagtgc gttttaccgc
     1261 accttcaacc tggacatggg tagatcacat ggtttcgggt ctacgactac atactcaaac
     1321 gccctattca gactcgcttt cgctgcggct ccgtctcttc gacttaacct cgcatgcaat
     1381 cgtaactcgc cggttcattc tacaaaaggc acgccatcac ccattaacgg gctttgactt
     1441 gttgtaggca cacggtttca ggttctattt cactcccctt ccggggtgct tttcaccttt
     1501 ccctcacggt actggttcac tatcggtcac tagggagtat ttagccttgg gagatggtcc
     1561 tcccggattc cgacggaatt cctcgtgttc cgccgtactc aggatcctcc taggtgcctt
     1621 ccaaatttca tctacggggt ttttaccctc tttgactgac ttttccaagt cattcgatta
     1681 tctgaaagaa ctaccatatt ggagtcctac aaccccaatg agcaagctca ttggtttggg
     1741 cttttcccgt ttcgctcgcc gctactcagg gaatcgaatt ttctttctct tcctgcaggt
     1801 acttagatgt ttcagttctc tgcgtctacc tcgaatgcgc tatgtattca cgcaaacgta
     1861 acatcctata aaagatgttg ggtttcccca ttcggaaatc tctggatcat agcttacgta
     1921 cagctcccca aagcatatcg gtgttagtcc cgtccttcat cggctcctag tgccaaggca
     1981 tccaccgtgc gcccttattc acttaacctt atcaaccttg cggttgggtt ttgatctttc
     2041 ttctagcgat agaagtccga tcaagaaaat aagcaattga acttattaaa aaactctatc
     2101 cagctaaaca agtgtttagc cttcaaattc aacgcggtgt tctcggtttg tattacttaa
     2161 tttacttcaa atatccagtt ttcaatgaac aaagtattct cttgagagta tcttctaatg
     2221 tcaaagtcat aagctgactc ttcaattatt gagtagacct ctcaaaactg aacaaagtat
     2281 aaaacaacca gtgtagtctc cgtaatattc cttagaaagg aggtgatcca gccgcacctt
     2341 ccgatacggc taccttgtta cgacttcacc ccaatcatct atcccacctt aggcggctgg
     2401 ctccaaaagg ttacctcacc gacttcgggt gttacaaact ctcgtggtgt gacgggcggt
     2461 gtgtacaagg cccgggaacg tattcaccgc ggcgtgctga tccgcgatta ctagcgattc
     2521 cggcttcatg taggcgagtt gcagcctaca atccgaactg agagaagctt taagagatta
     2581 gcttagcctc gcgacttcgc gactcgttgt acttcccatt gtagcacgtg tgtagcccag
     2641 gtcataaggg gcatgatgat ttgacgtcat ccccaccttc ctccggtttg tcaccggcag
     2701 tcttgctaga gtgcccaact aaatgatggc aactaacaat aagggttgcg ctcgttgcgg
     2761 gacttaaccc aacatctcac gacacgagct gacgacaacc atgcaccacc tgtcactttg
     2821 cccccgaagg ggaagctcta tctctagagt ggtcaaagga tgtcaagacc tggtaaggtt
     2881 cttcgcgttg cttcgaatta aaccacatgc tccaccgctt gtgcgggccc ccgtcaattc
     2941 ctttgagttt caaccttgcg gtcgtactcc ccaggcggag tgcttaatgc gttagctgca
     3001 gcactgaagg gcggaaaccc tccaacactt agcactcatc gtttacggcg tggactacca
     3061 gggtatctaa tcctgtttgc tccccacgct ttcgagcctc agcgtcagtt acagaccaga
     3121 gagccgcctt cgccactggt gttcctccat atatctacgc atttcaccgc tacacatgga
     3181 attccactct cctcttctgc actcaagtct cccagtttcc aatgaccctc cccggttgag
     3241 ccgggggctt tcacatcaga cttaagaaac cgcctgcgct cgctttacgc ccaataaatc
     3301 cggacaacgc ttgccaccta cgtattaccg cggctgctgg cacgtagtta gccgtggctt
     3361 tctggttaga taccgtcaag ggatgaacag ttactctcat ccttattctt ctctaacaac
     3421 agagttttac gatccgaaaa ccttcttcac tcacgcggcg ttgctcggtc agactttcgt
     3481 ccattgccga agattcccta ctgctgcctc ccgtaggagt ttgggccgtg tctcagtccc
     3541 aatgtggccg atcaccctct caggtcggct atgcatcgtg gccttggtga gccgttacct
     3601 caccaactag ctaatgcacc gcgggtccat ctatcagcga cacccgaaag cgcctttcaa
     3661 atcaaaacca tgcggtttcg attgttatac ggtattagca cctgtttcca agtgttatcc
     3721 ccttctgatg ggcaggttac ccacgtgtta ctcacccgtt cgccactctt ctttttccgg
     3781 tggagcaagc tccggtggaa aaagaagcgt acgacttgca tgtattaggc acgccgccag
     3841 cgttcgtcct gagccaggat caaactctca taataaaagt tagaacaatc ttgcgattgt
     3901 taagctcaat ttgtttgcta gcatattgct tgcttgttaa aaatgtttgt tgtcttgaat
     3961 caatcaagac gccctacaca tttggtttgt cttactttgt tcagttttca aaggtctact
     4021 tgaattgccg tagcaacttt tatatcatat cagagtgaca agtgaatgtc aactgttttt
     4081 taaaagttat tttcgatttc gcatttagaa atctttcagc aactcatata tcataactta
     4141 tcttttgtta tttgtcaaga acttttttta agtttttctt gattagatca agcttttcaa
     4201 taggttcttt ttaaacgact tagttatctt atcatgtggt cacccacacg tcaagaactt
     4261 ttttcattgt ttttttgaac gtttcaaaaa agaaaaagtc taataaaaac aacagaaatg
     4321 aatatatcat gtaaatttgc acatgtcaat acaaatttat actcaattta ggtactctcc
     4381 tcccaacaaa aaaaggaaat gagcagttgc cacttcctct aaatagtatc tattcctctt
     4441 cgtttttact attcacttaa aatcaattgt tccattagtt gttcgttgta tccaacaaat
     4501 agaacttcat caataataat caaaggtcgt ctcaacagct ccttatattg tttacacaat
     4561 agagctaatt gttttttgct gatcgaagtt aaatccactt gaatatcttt aaaggcttcc
     4621 gaccaagtga cgaataattg ttcagtgtgc atttcatcaa agttacataa ctcttctgct
     4681 tcggtcatgg ttaattcctg ttgttccaaa tcaatgaact gatacgtcag ttgattggat
     4741 tctaaccaat tcttggcttt taggcacgtc acacaatgca gtgaaccgta gattttcact
     4801 ttcatcctca caaggtccct cctttttagc tgaaaatact gttctgcata tagatcaaat
     4861 tacgcgcgac ggagcggatc tctcttggaa caaatgaacg aatttcatct tcattgaatc
     4921 caatcaatat tcttttttca tctattaaga tcggtcttct tagcaatgat ggatattctt
     4981 tgaagagaac gatcatttgc ttcaaggaca attcattaaa atcgatagcc aacttttcat
     5041 atatttttga gcgagtagaa ataatatctt caactcctcc ttcagtagct gcaagaattt
     5101 cacggatttc actctctgtt atcgggtcgg caaaaatatt tttctcttca aaatctaatc
     5161 gattagcttg caactatgcg cgagcctttc tgcaggaagt acagctaggt gaagtgtata
     5221 cttttatcat tttctcactt ctttttaatt ataatcccat tctaaccgaa tctcataaaa
     5281 aataccaatt attagctata aaattcatga tttttttacc tttagtaatc tatatctcta
     5341 gaaagcttgg catatcagca ttttctatta ttatttagtt ataatctttt tttataaaaa
     5401 taaagaaaag agcaagaata taaacaaaaa aatttatatt cttgctcttt tcagttatat
     5461 atcgattgtt ttttaatttt acaaccagtt tctctaataa atcttgaggg ttttaatcga
     5521 cgtgttccct tcatcaaagg aatacacaga tacagtcgat tccttgctct tgtcatcgcc
     5581 acataaaaga ggcgtcgttc ttcttctata gtagttagat gctctgcctt tatctgtttg
     5641 ttgcttaaag catttttttc agttgctcca ttataaggga tcagtccttc attgcaacca
     5701 atcaaaaaga cattccgata gctcaatcct ttacttcgat gaatgctttg gatgcacaat
     5761 gcatccagtt ttccttgacg ataagcagtc aggcggattt ttaattgctt tgctagtact
     5821 tgtatttctt tctctaagcc cattagttga gtcagtgtcg gatatttttt gatagtctcg
     5881 gacaaccatt ctttttccgt accatccatt tctttagcag gtttcagcaa ttttagaaaa
     5941 ccttttatca atgattcaat cttatagttc tcattttttt caagagcgtt gatttctcca
     6001 ataaaagagc gtagttcttt ttcctttgat ttcatattag gtctcactgc caagagatag
     6061 tttatgatat cttttttctt attctcattt gaaaaaaaga aatcacattc agctcttttc
     6121 agatagcagt tcatcattag ctgatgcaat aactgcttgt acgcatgatt ttttttctgc
     6181 tgcgtaggcg cttcgtgcca aagtactaat ttctgataaa actgttgaaa agtccgtata
     6241 ccaaatactc cttcatattg cccatctgct tccaatacga atggaatttc tgtttgtagg
     6301 aggtcttgga ctaactgttg cgtttgtgat aacgaacgat ataacacgat cgactcttta
     6361 tacttcccat tgctttttat aaaggactgg atctgtttga tgatccattt actttcagtt
     6421 tgtgtatttt caaaagacag agcactcata ataccagctt ctttttgtgc tggaaccatc
     6481 gctttgggaa tgcgatcgtt cttattgaat gtgatcaatc gattcgcacc ttgaacgatt
     6541 gcagcgcggg aacgataatt agtcagtaaa aacagggtct ttgcggggta ctcttgatca
     6601 aaatttttga tataagaagg ctctgaccct ctaaatccat agatactttg atcatcatcc
     6661 ccgactacga tcaacttgat atggctatct ttcgtgatca aacgtacgat ttcccattgc
     6721 aatggattcg tgtcttgaaa ttcatcgata aataggtaat catatttttc accgacatat
     6781 cgtctaactg cttcatcttg tagtgcagat tttaaatttt gcaacacatc attgaattca
     6841 aatagctttt gttctttttt ttgtttttgg agttcagaca tgagatactt cattcgctca
     6901 gaaatcggtt ttgttgcttt ttgttcaagc gagtcaaatt tgtcctggat cacttcaacg
     6961 atttcctcaa tcgacaaatt catattctgc caataatcca atcttgccga aatcgttttt
     7021 tctcccgact gatcaaatgc atatagatta tacttgcgga tcagctgttg gagtatacca
     7081 ttgattttat aagaagtatc tttagaaaat tccccttgta tccctgttgc cgttatttca
     7141 ggaaaacgtc tttggatgtc attgtacaaa cggaaaaaaa tgctgtgaaa tgtaccaata
     7201 tgcacattag tcttacgttg actaaaatta tctacgcgtt tttttaattc atttgccgca
     7261 ttccttgtaa aagtaatcat caatatccgt tgttcttcta cttgttcttg tgtcatcaag
     7321 taaacggcct ttgcacaaat cgtctgcgtc ttgccgcttc cggctccagc aataatccgc
     7381 aaatttttct ccatgttgta ggtgattgcc gctttttgtt cttgattaaa tcgattatac
     7441 gaacgttttt ccatcatatc gaaaaatgaa tggcttccat tatcttcttt ttcttcgtcg
     7501 atcaggcctg gagcttcgcc ataagctgcc tcataacttg caatgatttc ttcttgcatc
     7561 cggaaaattt gttggagctt gctgtacttt ttttcccaat gtttgagttc tctttgcaaa
     7621 cgaagaattt ctttttcgtt tccttgattg atagcttttc ccatctttct gttcatttaa
     7681 gttctgattc gtttccttta tactaacaga ccttacgcaa aaataaaacg gctttagcga
     7741 gtagattttt ttctgaaaat aatctttaat atttccgaaa aataaaagaa tgatgtggta
     7801 agatagtaaa gaaaatatat ctcagttgaa ggtgaaataa aaatgaatac ttcattccac
     7861 gaaggacgta cgattggtct tttgctaacc tttattggcg gtgctatgga tagttacact
     7921 tatatccaat acaatgcttt tgcttcagct caaaccggca atatcgtttt agcgattatc
     7981 caaagtttcg atggggaatg gctaagtgtc ggcaaaaagg ttctttctac gctgtttttc
     8041 tttttgggta ttttacttac taaattcctg atcaactatt tccagaaaaa agaaaagcac
     8101 ttttggcgac tatttgttct ctattatgaa gcagtgatct ttttcttagt cagtctgccc
     8161 tcgatcaatg ctcatcctgc acttgtaaca atcatgattg ctttcaccgc tgcaatccaa
     8221 tggcttgcct ttgacaaaat cgatggacgt gcctacacga atctattcac aacaggaaac
     8281 ttaaaagggg tagcaacgaa tctctacgac tattgggtaa caagagaaaa agcagaattt
     8341 gatcgattca tccattttct tacagtggta cttgcattta tcgcaggcgc aatcgttcaa
     8401 gtcttttttc atcatttatt caatacgttc tccattttat tagtctctgt tttatttttg
     8461 atcattgcaa ttacccaaag cgttcaactt tggcactttt atcgtcaaaa tcctttcata
     8521 gtaaaaaaat aaaaatatga gatgtgagtg ggacaaaagt aagaaacact tctgtcccag
     8581 cctcacctca tatttttctt atgaaaagat tcctttcacc ttttcacgat ctgttgtgta
     8641 acgagcgggc atttctaacg ctctttcttc tatttttttg gtgtgcggat taatcaaacg
     8701 aacgatttct tcccctgcag atgggtcttc gacaaaatca tatttatctc catcgatcac
     8761 catttttgga cagatatcaa aactttcata ccattcttca taacggcgat tcaactcttg
     8821 ataatacgca tataactcag ggtcttgttc tagttgttcg tagattcgtc ctcttttttt
     8881 gatacgtgct aacatcgttt caaaggaaac acggatatag actaacagat ccggcttttt
     8941 tggtggggca acagcttcta attctttgag cactgtttcg agcaatcctt gatattgcgc
     9001 gacttcctct tgagagactc tacctagatc tgcatttaaa tggaacagta ggctatcttc
     9061 gtagattgaa cgatctaaca cattatcatc atggctgaac gcatctttga ttgccatgaa
     9121 tcgtttattt agaaagaaaa tttgcaatag aaaagcatac ttatctggat ttgaataaaa
     9181 aagtggcagt acctcattat cctctacatt ttcatagaat ggtttcgttt ctaaattgcg
     9241 cgcaagcatt tctgtgagtg tactctttcc tgcaccgatc gtaccagcta ctataatcat
     9301 gtttgtttgc cacctttctt tttttgagtt atcgaccatg gccgaaacgt attcttattt
     9361 tacatctgtt tcacatgaca cacacgttat gtatgttcga tacgtttttc attctactac
     9421 gctgatcaga gaaataaaag tatcattgtt aaatctttaa catcaaaaat agactgattg
     9481 cttcgtttta tttgctcacg aatatcagtc tattcttcca ttattgattt atttttcatt
     9541 ctgtcacagc acttgatttc cgaactacca gttgccattg aaggttgtgc gcagtatcgt
     9601 tatcttccgt cgcacaattg attacacgaa tcatcacact attttcgtaa accttctcaa
     9661 tttctccttt aacaggcgca ccaaataaat cggatttaaa tgcatatgcc tctccaactt
     9721 caaataattg ttcattttcc ataaaaaatc cctcccaaac cttttctaaa ggctattaaa
     9781 tatttaccac aaaattgaag aaataacaca ataaactcct aaacggttct tttcatgtca
     9841 aaactgttca ttttttggtc tctctgtgaa aaagtggact gtccatccat tcaaaaaagg
     9901 gagtattatt tttacgattt tgaccccaaa acaacctttt atgaatcaaa actctatttt
     9961 gacccttttt gacatagaat attagtcgga ggtacgttag atgaaaaata aagttgtgaa
    10021 caaattattg gagacattat tcagtggtga aaaaacagaa gaagatatgg tttatatcca
    10081 agttaagttt gctcttgagg tgctgatgaa caacctagga aaattagcag ttgtgctagt
    10141 ctttgcttta gcgactggct catggagcga aacaggaata acttttcttt cctatatctg
    10201 tattcgtaga tatgcgtatg gacttcactc tgattctgaa tttgtctgcc tactttggac
    10261 tttgctttat ttgtggggcg ttccacttct gatgaaacat tttgaattga ctgtctcctt
    10321 cccatggatg gtctttttat tagtcagctg ctttttatta ttgcttcgct atggatcaag
    10381 aggtacagct attaatccca ttgaaccaga aaaacgccca cctttattga aaaaagcaat
    10441 tttcatgttt gttgtattca cacttctgat cttatttttc gctaattctt acttttctac
    10501 ttacttgctt ctcgggattg ttttagaaat agctacgttg cttccaatta caaactacct
    10561 aatgaatctt ggaggaattt tttatgaaaa aaacaatcat taaacaactt accaacttat
    10621 ctgacttttt tgtatctggc tgctgcttcg gtatgagctc agaatttaaa atccctgaaa
    10681 aattaaaaaa ataattaact agttatgcta taatttggaa aaaatcaatg ggagcggtac
    10741 tttatgtttt tatggtccat agcgttgcaa tacttgattt atacgatttg tatattactc
    10801 attgaacacc aaattaaaaa taaaatcttt tttgcaggag tcatcctgct atcttgtttc
    10861 ttactaggtt ttatttatcc gattttaggg atttttactg ccttatttgc tattggaatg
    10921 ctgatgctta catttttctt ctttacgtct tcaccgcaac ggttgattta tgcgcttcct
    10981 tggggactgc tgacatcact tttaggagat catttggcta gcatcagtga ttttttggtt
    11041 ttggaatcag cggtgattga acctggagat tctttacaat actttcatat tgtcgtatct
    11101 gctgttttgg cagccttact agcatttggc tttaagaaag ctttagagag attctatgga
    11161 ttagatcgtc gaatgattgg cataattggt acattgatat tatttacata ctatatcatt
    11221 atcttttaca cccgtttttc tggcgaaact cctgaagtct tagctttaaa taccagtttc
    11281 tttatatttt atctttgttt tggtgtaatc atccttgtct actattggaa aatttcgaat
    11341 aaaaaaatgg cagaccaact attagaacaa cggatccaac ttcaacaaga ctatatcaaa
    11401 gatcttgaaa agaactacca agatttacgg gaatttaagc atgactatca gaacttactt
    11461 ttttcgatga atagctatct tgaggagggg gatcttgacg gattacgaaa gtattatgat
    11521 caaaatatct tacctactcg gcaaatgatg caacttttcc cagctaacct cagtctttta
    11581 gacaacatga agaatcggga tataagaagt ttgctttctt tgaagcttat gatggcgcaa
    11641 gaaaaaggct tgtctgttca acttgtattt cctgatgaaa tcaagcttga taaaaagcat
    11701 acggtcaacc ttgttcgtat gttagggatt atattagata atgctattga aggtgcttcg
    11761 attactaaaa agaaaaaaat agaattgatc gtacttaaaa agaataactc ggtgattatc
    11821 cgtgtaataa atactacttt gaatactctt cccctgaaca aactaaaaca acaaggattt
    11881 tcaactaaga gcaatccaaa aaatgaaggg ttgggattat tcatccttga tgaattgacc
    11941 aagctaaatc cttatatctt tttggaaact tcgattgaaa accaacgttt ttctcaaacg
    12001 atttatatac aaatgaaata aaggagtaaa tttatgattc ccatttatat ttgcgaagat
    12061 gacatgaagc aactagaagt aatctctgct gtaatcaaaa atcgaatcat gattgaaaat
    12121 ttggatagtt atgtccatgt agctacttcc gatccaatgg aacttcttca agctgctaga
    12181 gttcgcacct catcttttgg catttatttt ttagacatcg aattaaaaga tagtgagcta
    12241 gacggtatca tgatcggcaa acatatacgg gatctcgatc cattagggaa aatcatctat
    12301 gtgacttccc acacggatct ttcgatgact atcctgaaaa gcaatatcga accaactgat
    12361 tatattatca aagaagatgt ctttgaccta aaagaaaacg tcgaacggat tttgagcaag
    12421 attttcgagg atgtccaaac tacacctctt caaaaagata tttttaaaat tgaattcaac
    12481 gatgaaataa agtttttacc aatcaaggat attcaatatt tttcgacgtc acccggtaca
    12541 ccgcataaat tagaagtcca tttgacacat gcgcaaatgc aattttacga taaaatcaaa
    12601 gaaatcgaaa aaatgaatca gcatttcatt cgctgtcata agtcttatgt gatcaacaca
    12661 caaaatgttc ggacgatcaa taagaagacc cgtgaaatca ctttagctaa tggtgaaatg
    12721 atccccgctt ctgtccgtgg tctaaaaaaa ctgatttctt aactttataa taactctcct
    12781 ttctttttta ggctctaggt caaatagtgt tgctttgaat taaatcatga aaaggagacg
    12841 ttccggcgtt tccttttttg tgtgattaaa tgatttcgca aaaatcttgc tagatcagaa
    12901 ttctctttct aaggtgacga aaggttctaa aaccaaatgc gattcttttt atgatcttgg
    12961 tcagtatgag ggaagtaaca aaatcagcaa ggtagtcgat agtgataaca agtttttagt
    13021 tgctgaattt tcaaattttg cagcttccga aacggtagcc gttactagaa cagataaaga
    13081 ggttattgta gagaaaactg caaaaggata taatgggaaa aacaaagtta catgagagag
    13141 ttatccgtta gctacgaagg atgagaattt tgaatataga attccaccac aatcgtccta
    13201 tagatcttgg agacatccaa atttgcaata ggaattcatg ttttttcaac acttactaat
    13261 tttggtgttt cagctttagt aacttttata gctggaattt ttggtattgc gacggcagaa
    13321 gctaggctac tgcttgatta tatggatgca aaaggtttgt ttactggttc tgcggttgct
    13381 gctgcattag atacaagtgg aaatgggtgg attggtttgt atattcgaga tgtatggaat
    13441 gtttccaaag cagtagatat tggaacacaa tataagacga tgtaaggggg aaaaatgaaa
    13501 aaagcggatg ctaaatctat aataagtata tttgtaggtg tatttctttt aatgggtgtt
    13561 atcgaattta tttttaaaag aaatcattca tttattcttt ctaatcatta ttttgagttt
    13621 ctgttaggtt ttattgttat gaatgctttt cctattggta gaggatgggc aaaagtgaga
    13681 tattttactt tagtttttct aagtttttat ctgccaataa agattgggga cttattaagt
    13741 gttgagggat taaatattac actaggaaca tatcttattg ttttaggtat ctttcttttg
    13801 attgttggtc cattttttta tcgaagaatt gctcatagag tgaaataatt attttctcaa
    13861 aaaggaataa aaaaagagtt cggatgtgaa ttggctctct ttttattcct tttttttgag
    13921 tggagtaagt gataaactgt gattatgtta ttctattaag gattagaaaa tgagagagag
    13981 attctaaggt catttcagaa ttttgtgtgg ggaattatcc gttaaaacgc gctgaaaaaa
    14041 cgtcaaaata taacgaatag gttattttta aattgagtaa tttcacaaac ttttaaaaag
    14101 agaaaataag taaggatcta ttatttttaa ctagaccaat ttcatttcac aaagtcggat
    14161 gtaaaaaggc ttggtaacac tggtacttgg tagtatacac attatgcaaa ctaactaaat
    14221 aaataacatt tttaaccctc tggtaattac ttgtaattac tctctttttt tgttacaatg
    14281 tacttactaa gtaattacta tttattggaa atgaggagta tatatgatta caaaaacaag
    14341 aaaacaaggt aattctatta tgttgacagt tcctaaagac tttaatgttc cgaatggagt
    14401 agaagtcgag gcaaaacttg tagaaaatgg cattctttat gaatttgttg aaccacaaaa
    14461 ggaattcttt gattttagtg aagatatttt gtctgatata atcgcagaag gctacgataa
    14521 agataaaatc cttgtagagt ttaagaatag aaaaaacaaa atggtttctt cttttagtaa
    14581 tattgctaca gatacactta ctaattctaa ggctatgact aaagaggagt tggcaaaaga
    14641 aattgggtta tgagatcgtt ccttcaaaac atgtcattaa gtatctaaaa aagataaaag
    14701 aaaagccttt aaaagagaaa tttttaatta ttatttatga cgagattgca attaatccat
    14761 attcaggaag tcaaaaaact agggatttat caggtatttg gtctagggga tttacgtatg
    14821 caggaactac ttatagaatt gcttatgaaa ttgaagaaaa tatggttatt cctgtattgt
    14881 tatgtggaac ccatgaaaat ttctatgagc agttaaagaa tataaaagga taataagttt
    14941 ctgtcttttt agaaggaata ggcacgtgtt agttttgttg attattgacc ataaaaacca
    15001 aaaaaataac catctaaaca ctttgacagg agttagatgg tttgaaaaaa gttaataact
    15061 gtcatcgtct ttttaaggct ctaagtcaaa tagtgttgtt ttaagccaat caaaaaagcc
    15121 cataggacac atccaagtga gcccccaaag ttagaacaaa aatctacctt tgggagctca
    15181 cttcacatat caaacttagg cttattttat ttttaagaag gactattgtc ccacttcgat
    15241 tatagaacta ttttttaatg tactatctca caactacttt gtttaaagtg gaatttttgc
    15301 ttaatgcaac atcatttctt gtgcaatttc ctggccattc atttgtgctg gataaaaagt
    15361 cggccaattc tccatttctt ctaacagctt ctcttgactc tcattcccta aatagatatg
    15421 gaaatgttct gaatcacttg gttcaattga atgatcactg aattggacat agcgatatgc
    15481 actattttgt ggttctttcg cctcaaatag atagcgtaca cctcggttac ctgcctgata
    15541 atccaacact tttttgccac tgtaacggta ttctgctttt ttcacttcgc catttttaaa
    15601 tgtaaatgtc aactcgttcc ccttgatcgt tatctttgcg acatctgtgt gatagccaac
    15661 tttataatat tctttatact ctttcgccgt cttttctgga ttcacttttg ccttgtattc
    15721 aaaaactgga tctagtgttc cattttcaag ataagaatcg acagtctgcc acgcaccgtt
    15781 ccaatccaat aacgtacggt ctttgaccgc tgaatcttca aagtagccat tgtatacggt
    15841 cttttcttcc tgttcccatc tatcttcaag ggggttctct atttcagtcg ttttttgtaa
    15901 cgctctcaga tttttctcca tgatcgaaag gtagttttct ccctgtgcca tttgttcctt
    15961 cgtcaatcct tccaacggat taagtacctc taaagaaact cctgcttcat tcgctagtgt
    16021 tttagcaata ctacctttcg tattttcttc gaaatagata gtgctgatcc catgttccgt
    16081 tacgaattcc tttaattctg ctattcgaga aacagaaggt tcttcgcttg aagataagcc
    16141 cgtaactgcc acttgcttta gcccatactc caatgctaaa tagttgaacg ctgcatgttg
    16201 tgtaacaaat gatttttgtt ttgcttgccc caaggtatct tgatattttt ggtgtaggtt
    16261 ttgtagtttt gttaggtagt tctccgcatt acttgtaaaa acttcctctt tttctgggta
    16321 ttgttttatc aattgattac gtatcgtctg aacctgtttc actgctaaac ttggcgccaa
    16381 ccaaacatga gggtctaatt cgtgggtatg cccctcccct tcatgagtat gatcatgtcc
    16441 gtcttcacta cctgacaata aaagcattcc ttctgttgct ttgatcgaca ataccttccc
    16501 ttcccgcaag gtttcttgaa ttgctggaac ccatgtttcc atattttcat cattatagac
    16561 aaatatatct gcattttgga ttttagtcat gtccttagcg gatggttcat aatcatgtga
    16621 atctgttcct gcggggatca ataattccac atttccttct tccccaacga tttctttagt
    16681 gaactcatac attgggtaaa aggttgtcaa cacttgcagc tcttcatttt tcccagcttc
    16741 ttggttactt ccgcaactag caaggagacc aactaataat accccactta acaaaccaat
    16801 caaacgtctc atctttgtta cactccttct catcttcttt ctttgttctt ttacgattaa
    16861 ctccattaaa tcgtaatcgt tacgttttaa tagcaagaat aaatttagca tatctctaaa
    16921 acataggtca agtgtttttt ggttatttaa tcgttgattt gaacatccga acctttatca
    16981 ttttcttttt ggccctattt ccgactataa tgaaataaat catctctcac tttagtaaaa
    17041 tttttatgta cttacttgtt cgagatgttc tgacttatta gaaaggagaa aaaaagtgga
    17101 aaataaatcc aaagaaaatt cacggttcat acggttttta gggggaaaaa cttcttacta
    17161 tgttttaggt ttattgatca tgttggcttt agtcatttac attttccaaa aggttggctt
    17221 tgtttttaaa ccatttattg tgatttttgc tactgcctta ccacccgttt tatttgcttt
    17281 aattctatat tatttattag atcctttaat caaacgtttg aataaaaaac tatccagaaa
    17341 tctatcagtg gttattgttt atatcgttat tttgatgctg atcggactag gaagcatctg
    17401 gctgatccca tttctgcagc agcaagctaa aacactgatt gcgagtttcc cggacttatt
    17461 cgctgatttt cagcagacac taaaacaatt tttggcgcaa acaccatttt cagatgcgtt
    17521 caatcaattt ttttcatcta ttgatgatct tacttcaaat tttacctcct tcattggaga
    17581 ttattgggaa agcggggcta agagtttagg gaacatcttt tcagcagtca ccactacttt
    17641 tattacatta tttactggcc cgatcattgc ctttttccta ttgaaagatc ctcataaatt
    17701 ttatcaatca gtcttaggaa tcgttccacc gaaattccgt acggattttc aaacattgac
    17761 aaaaatcgcc aatcagcaac ttggtgcatt tttgaaagga caaatcattg cttccttcat
    17821 tttaggtgct gtctattggg tgactttttt attgattggt ttagaattcg caagcatatt
    17881 agcgattgct gcaggtatcc tatgtattat tccttatatc ggtcctttta tcgccttctt
    17941 ccctggtcta tttattgcct ttcaggattc aacgtttatg gcgataaaat ttatccttgt
    18001 ctggtttatc gtgcaactac tccatggtga tctagtcgtt ccgcgagtga tgggcaatcg
    18061 tttacagatc catccgatta cgatcctgat cgttctacta gtcatgggtg atttgttagg
    18121 acttatgggt gtcatttttg gtattccgat ctacacgctg atcaaattgc ttgtcgtctt
    18181 tacttttagg aaattcaagc aacgctacaa caagttctac ggtgatcaag gtgtttatca
    18241 aaaagcagat ttttcagaga aagattacct agataaagaa taactataag ttagatacaa
    18301 aaatgagata atcctactga gtaaagagaa ctaaaatttt ttgtctctat cctttgaggt
    18361 caagacaaaa gtcgtttagg tttgaaaaat tggatagaaa agggagtggg acaaaaatca
    18421 gtttttttct gatttttgtc ccactctctt catttatacc tcttacgcaa ttcatccgtc
    18481 tttcttgata aagaactact ttttgaagta acctatttcg agtatttttc tagttattct
    18541 ttcaataatg caatggcttg atatggtttc aatttcaact cacgttcaac gattgttcca
    18601 tcgtaattat cgatcaatat cttggagtct aaaaattctt ctggtaatga aatagtcgtt
    18661 tctttaccgt agaaattagt aaatacgatt actttctttt cttcatattg ccgtaaaaaa
    18721 ctatatactt gtggatgttc cggctggtat gcctgataac ttcccaaggc aattactggg
    18781 tactgttttc tcaatcggat caatttttga taataattga aaatagattg cggagaagca
    18841 agttcttttt caacattgat atccccatag ctttctgcta cctttaacca tggttttcct
    18901 aatgtaaacc cagcattttc atcggctgtc cactgcatcg gtgtacgtga attatctctt
    18961 gatttggctt tgatccggcg gaaagcttct ttttttgata agcctttttc cagtaataga
    19021 tgatacgcat ttaaacattc gatatccaca taatcagcaa tcgaatcaaa gtcaggatcg
    19081 atcatgccga tttcttcgcc catatagata taaggcgttc cccgatttaa gtggatcatg
    19141 gtcgctagca tttctgctcc ttgttttcgg tagctatcaa ctgctacaaa acggttcagt
    19201 gcacgcggtt ggtcgtgatt attcaaaaat aaagcattcc agccattccc agcactcatc
    19261 tcttctcccc aagtatggaa caatcgtttt aattcttcaa aatcaaacgg cggagtggtc
    19321 cacttgtccc cattttcata atcaactttc agatgatgaa aattgaaaac catggaaagt
    19381 tcattccgac tcggttctgt atataaaatg cagttctcaa cggttgttga actcatttcg
    19441 cctacagtga tgatctctgc gtcttgacca aatgtttctt tgttcaaccg ttgaagatac
    19501 gtatgggtga ttggtttatc cgtgtattct ggtttacctt ggttctctga attgtttttc
    19561 aagacttcat cttttccgat gacattgata acatcaaaac ggaagccttt gactcctttg
    19621 ctcatccaaa aacgaacgac cttgaataac tcttcttgga ccgcttcatt tcgccaattt
    19681 aagtctgctt gtgttttgtc atataaatgt aagtagtatt tgccagtgtc cccaaaaggc
    19741 gcccaagcat tcccaccaaa tttagatatc caatcagttg gttcatctct tagaataaaa
    19801 aaatcttgat agaatggatc atctgctaaa gctttttgaa accattcatg ttcaatcgac
    19861 acatgattca ataccatatc caacatgatt tcgatctgat aacttttagc ttcagctact
    19921 aatgattcaa attcctccat cgttccaaaa agaggatcga tcgcgatata attggaaata
    19981 tcatacccat tatctttttg cggacttggg taaatagggt tcaaccagat catatcaatt
    20041 cccaattcat gtagataagg aagtttttct ttgatgcctg ctagatcgcc aatcccatca
    20101 ccattgctat cgcgataaga tttaggataa atttgataaa tgactttgtc tttgaatgtc
    20161 atattgattt gcctccaatc aactgatcac aaacttatat atacaagttg ctaaattcat
    20221 tataaccaaa aaggaagcgt ttgtaaaact tttgctcaat agttctccaa atcctttaga
    20281 caacgactca ctcaaaagaa agagcacctc ttttttgaga ccgttcacta ttcaaagaga
    20341 caatggtcca aaaataagcc tgtacaactc acaaataaac gacgattgcg agttgcacag
    20401 gcttttagaa cgaaacattc tacaatttcg tttgtttcct tctattcatt tgattttagt
    20461 gcatcgatca tattgatatg ttttaacttg aagtgagtca cgatcattac gatcacggta
    20521 aacaatatcg ttaaaatact tgaaagtgca taagctttcc aagtaatcac taatggaaag
    20581 atgacatttt ccatagaggc ttg
//
