LOCUS       NZ_CP096201.1          10624 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP096201.1 Kluyvera ascorbata strain SK chromosome, complete
            genome.
ACCESSION   NZ_CP096201
VERSION     NZ_CP096201.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:26:16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4996065
            Orig. end    :: 5006689
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10624
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5001065:5001689](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5624)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10624
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10624
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="3"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(884..3679)
                     /locus_tag="ctg1_4661"
                     /transl_table=11
                     /translation="MVQIPENPLILVDGSSYLYRAYHAFPPLTNRAGEPTGAMYGVLNM
                     LRSLILQYQPTHAAVVFDAKGKTFRDELFEDYKSHRPPMPDDLRAQIEPLHTMVKAMGL
                     PLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPD
                     EVVTKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYGEPEKIA
                     GLTFRGAKTMAAKLEQNKDLAYLSYKLATIKTDVELELGCEQLIVAEPAADELLTLFKK
                     YEFKRWITDVESGTWMQAKGSKPAVKPAGKAADVEIEVEVEETAATLSSENYVTILDEA
                     TLVSWIEKLKKAPLFAFDTETDSLDNISANMVGLSFATEPGIAAYVPVAHDYLDAPDQI
                     SRERALELLKPLLEDEKLLKVGQNLKYDRGILANYGIELRGIAYDTMLESYTLDSVVGR
                     HDMDSLSDRWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWP
                     KLQKHEGPLRIFNEIEMPLVPVLSRVERNGVKIDPAVLHAHSQEIAKRLVELEQKAYEI
                     AGEEFNLSSPKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRG
                     LAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQ
                     AFIAPEDYLIVSADYSQIELRIMAHLSRDEGLLKAFAEGKDIHRATAAEVFGLPLESVS
                     NEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLDYMERTRQQA
                     KEQGYVATLDGRRLYLPDIKSSNGARRAGAERAAINAPMQGTAADIIKRAMIAVDKWLE
                     SEKPRVRMIMQVHDELVFEVHKDDLDAVSKKVHELMENSTTLDVPLLVEVGSGENWDQA
                     H"
     aSDomain        complement(887..3655)
                     /aSDomain="TIGR00593"
                     /aSTool="tigrfam"
                     /description="pola: DNA polymerase I"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_4661_0028"
                     /evalue="1.00E-288"
                     /identifier="TIGR00593"
                     /label="ctg1_4661"
                     /locus_tag="ctg1_4661"
                     /protein_end="931"
                     /protein_start="8"
                     /score="958.5"
                     /tool="antismash"
                     /translation="LILVDGSSYLYRAYHAFPPLTNRAGEPTGAMYGVLNMLRSLILQY
                     QPTHAAVVFDAKGKTFRDELFEDYKSHRPPMPDDLRAQIEPLHTMVKAMGLPLLAVSGV
                     EADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPDEVVTKYGV
                     PPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYGEPEKIAGLTFRGAK
                     TMAAKLEQNKDLAYLSYKLATIKTDVELELGCEQLIVAEPAADELLTLFKKYEFKRWIT
                     DVESGTWMQAKGSKPAVKPAGKAADVEIEVEVEETAATLSSENYVTILDEATLVSWIEK
                     LKKAPLFAFDTETDSLDNISANMVGLSFATEPGIAAYVPVAHDYLDAPDQISRERALEL
                     LKPLLEDEKLLKVGQNLKYDRGILANYGIELRGIAYDTMLESYTLDSVVGRHDMDSLSD
                     RWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPKLQKHEGP
                     LRIFNEIEMPLVPVLSRVERNGVKIDPAVLHAHSQEIAKRLVELEQKAYEIAGEEFNLS
                     SPKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTY
                     TDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDY
                     LIVSADYSQIELRIMAHLSRDEGLLKAFAEGKDIHRATAAEVFGLPLESVSNEQRRSAK
                     AINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLDYMERTRQQAKEQGYVAT
                     LDGRRLYLPDIKSSNGARRAGAERAAINAPMQGTAADIIKRAMIAVDKWLESEKPRVRM
                     IMQVHDELVFEVHKDDLDAVSKKVHELMENSTTLDVPLLVEVGSGENWDQAH"
     PFAM_domain     complement(896..2017)
                     /aSDomain="DNA_pol_A"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00476.22"
                     /description="DNA polymerase family A"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4661_0079"
                     /evalue="3.30E-160"
                     /label="ctg1_4661"
                     /locus_tag="ctg1_4661"
                     /protein_end="928"
                     /protein_start="554"
                     /score="533.3"
                     /tool="antismash"
                     /translation="LHAHSQEIAKRLVELEQKAYEIAGEEFNLSSPKQLQTILFEKQGI
                     KPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRV
                     HTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYLIVSADYSQIELRIM
                     AHLSRDEGLLKAFAEGKDIHRATAAEVFGLPLESVSNEQRRSAKAINFGLIYGMSAFGL
                     ARQLNIPRKEAQKYMDLYFERYPGVLDYMERTRQQAKEQGYVATLDGRRLYLPDIKSSN
                     GARRAGAERAAINAPMQGTAADIIKRAMIAVDKWLESEKPRVRMIMQVHDELVFEVHKD
                     DLDAVSKKVHELMENSTTLDVPLLVEVGSGENWD"
     PFAM_domain     complement(2120..2683)
                     /aSDomain="DNA_pol_A_exo1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01612.22"
                     /description="3'-5' exonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4661_0078"
                     /evalue="5.30E-42"
                     /label="ctg1_4661"
                     /locus_tag="ctg1_4661"
                     /protein_end="520"
                     /protein_start="332"
                     /score="143.6"
                     /tool="antismash"
                     /translation="YVTILDEATLVSWIEKLKKAPLFAFDTETDSLDNISANMVGLSFA
                     TEPGIAAYVPVAHDYLDAPDQISRERALELLKPLLEDEKLLKVGQNLKYDRGILANYGI
                     ELRGIAYDTMLESYTLDSVVGRHDMDSLSDRWLKHKTITFEEIAGKGKNQLTFNQIALE
                     EAGRYAAEDADVTLQLHLKMWPKLQ"
     PFAM_domain     complement(2867..3169)
                     /aSDomain="5_3_exonuc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01367.22"
                     /description="5'-3' exonuclease, C-terminal SAM fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4661_0077"
                     /evalue="7.80E-29"
                     /label="ctg1_4661"
                     /locus_tag="ctg1_4661"
                     /protein_end="271"
                     /protein_start="170"
                     /score="100.2"
                     /tool="antismash"
                     /translation="VPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLY
                     GEPEKIAGLTFRGAKTMAAKLEQNKDLAYLSYKLATIKTDVELELGCEQLIVAEPA"
     PFAM_domain     complement(3170..3655)
                     /aSDomain="5_3_exonuc_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02739.18"
                     /description="5'-3' exonuclease, N-terminal resolvase-like
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4661_0076"
                     /evalue="1.10E-54"
                     /label="ctg1_4661"
                     /locus_tag="ctg1_4661"
                     /protein_end="170"
                     /protein_start="8"
                     /score="184.7"
                     /tool="antismash"
                     /translation="LILVDGSSYLYRAYHAFPPLTNRAGEPTGAMYGVLNMLRSLILQY
                     QPTHAAVVFDAKGKTFRDELFEDYKSHRPPMPDDLRAQIEPLHTMVKAMGLPLLAVSGV
                     EADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPDEVVTKYG"
     CDS             4076..4984
                     /locus_tag="ctg1_4662"
                     /transl_table=11
                     /translation="MSRLLAAITLPISIALTILLTILCSIPIILAGIIKLILPVPVIWR
                     SVSVFCNFMMYCWCEGLAALLHLNPWLKWDIEGLETLNKKNWYLLICNHHSWADIVVLC
                     VIFRKHIPMNKYFLKQQLAWVPFMGLACWALDMPFMRRYSRSYLIRHPERRGKDVETTR
                     RSCEKFRAHPTTIVNFVEGSRFTPEKRLQTRSPYQNLLPPKAAGIAMALNVLGTQFDKL
                     LDVTLCYPENDKTPFYDMLSGKLTRIVVRVNLRPIDPEMHGDYVGDKNFKRRFQLWLNA
                     LWEEKDHQITDIKAEYKNAGH"
     PFAM_domain     4298..4762
                     /aSDomain="Acyltransferase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01553.23"
                     /description="Acyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4662_0080"
                     /evalue="3.90E-14"
                     /label="ctg1_4662"
                     /locus_tag="ctg1_4662"
                     /protein_end="229"
                     /protein_start="74"
                     /score="52.5"
                     /tool="antismash"
                     /translation="DIEGLETLNKKNWYLLICNHHSWADIVVLCVIFRKHIPMNKYFLK
                     QQLAWVPFMGLACWALDMPFMRRYSRSYLIRHPERRGKDVETTRRSCEKFRAHPTTIVN
                     FVEGSRFTPEKRLQTRSPYQNLLPPKAAGIAMALNVLGTQFDKLLDVTLCY"
     CDS             complement(5001..5624)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03651"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4663"
                     /sec_met_domain="TIGR03651 (E-value: 0.00017, bitscore:
                     19.9, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVWLALAGMILAFSASAAQITDGKQYVTIDKPVAGEPQVLEFF
                     SFYCPHCYQFEEVLHVSDNVKKKLPEGTKMIKYHVEFLGPLGKDLTQAWAVAMALGVED
                     QITAPMFEAVQKTQTVQTVADIRKVFTDAGVKGEDYDAAWNSFVVKSLVAQQEKAAADL
                     QLQGVPAMFVNGKYQLNPQGMDTSNMDVFVAQYADTVKQLVEKK"
     PFAM_domain     complement(5037..5507)
                     /aSDomain="DSBA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01323.22"
                     /description="DSBA-like thioredoxin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4663_0081"
                     /evalue="1.80E-28"
                     /label="ctg1_4663"
                     /locus_tag="ctg1_4663"
                     /protein_end="196"
                     /protein_start="39"
                     /score="99.7"
                     /tool="antismash"
                     /translation="QVLEFFSFYCPHCYQFEEVLHVSDNVKKKLPEGTKMIKYHVEFLG
                     PLGKDLTQAWAVAMALGVEDQITAPMFEAVQKTQTVQTVADIRKVFTDAGVKGEDYDAA
                     WNSFVVKSLVAQQEKAAADLQLQGVPAMFVNGKYQLNPQGMDTSNMDVFVAQY"
     CDS             complement(5652..6638)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4664"
                     /sec_met_domain="APH (E-value: 4.2e-42, bitscore: 142.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDKAFTFQTLHPDTIIDALFEQGIRVDSGLTPLNSYENRVYQFQ
                     DEDRRRMVVKFYRPERWSAAQILEEHQFALELVEDEVPVAAPILFNGQTLLMHEGFYFA
                     VFPSMGGRQFESDNLDQMEWVGRYLGRMHQTGRKSRFTARPSIGVKEYLIEPRALFEHS
                     ALIPAGLKDRFLKATDDLIDAVMGLWHGRFDALRLHGDCHAGNILWRDGPLFVDLDDAR
                     NGPAVQDLWMLLNGSQAERRMQLETIVEAYEEFSSFNSDELALIEPLRAMRLVYYLAWI
                     IRRWDDPAFPKNFPWLTGEDFWHRQIATFIEQVKVLQEPPLQLTPMY"
     PFAM_domain     complement(5877..6545)
                     /aSDomain="APH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01636.25"
                     /description="Phosphotransferase enzyme family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4664_0082"
                     /evalue="1.70E-42"
                     /label="ctg1_4664"
                     /locus_tag="ctg1_4664"
                     /protein_end="254"
                     /protein_start="31"
                     /score="146.0"
                     /tool="antismash"
                     /translation="TPLNSYENRVYQFQDEDRRRMVVKFYRPERWSAAQILEEHQFALE
                     LVEDEVPVAAPILFNGQTLLMHEGFYFAVFPSMGGRQFESDNLDQMEWVGRYLGRMHQT
                     GRKSRFTARPSIGVKEYLIEPRALFEHSALIPAGLKDRFLKATDDLIDAVMGLWHGRFD
                     ALRLHGDCHAGNILWRDGPLFVDLDDARNGPAVQDLWMLLNGSQAERRMQLETIVEAYE
                     E"
     CDS             complement(6714..6983)
                     /locus_tag="ctg1_4665"
                     /transl_table=11
                     /translation="MKCKRLNEVIELLQPAWQKEPELNLLQFLQKLAKESGYDGELADL
                     TDDILIYHLKMRDSAKDAVIPGIQKDYEEDFKTALLRARGVIKE"
     PFAM_domain     complement(6726..6983)
                     /aSDomain="DUF1040"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06288.15"
                     /description="Protein of unknown function (DUF1040)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4665_0083"
                     /evalue="1.70E-45"
                     /label="ctg1_4665"
                     /locus_tag="ctg1_4665"
                     /protein_end="86"
                     /protein_start="0"
                     /score="153.4"
                     /tool="antismash"
                     /translation="MKCKRLNEVIELLQPAWQKEPELNLLQFLQKLAKESGYDGELADL
                     TDDILIYHLKMRDSAKDAVIPGIQKDYEEDFKTALLRARGV"
     CDS             7053..7637
                     /locus_tag="ctg1_4666"
                     /transl_table=11
                     /translation="VNAQSQITGVVLAGGKASRMGGQDKGLMLLNGKPLWQHVADCLCS
                     QVNDVVISANRNLDIYRQSGLTVIADTLSGYPGPLAGLLSVMQQRTAEWFLFCPCDTPF
                     IPNNLVERLVAGRHDAPVVWVHDGDRDHPAVALAHRSLAPQIVDYLASGERRVMVFMRQ
                     VGGHSVDFSDMKAAFRNMNTPEDLQLNQEKS"
     aSDomain        7071..7616
                     /aSDomain="TIGR02665"
                     /aSTool="tigrfam"
                     /description="molyb_mobA: molybdenum cofactor
                     guanylyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_4666_0029"
                     /evalue="2.90E-69"
                     /identifier="TIGR02665"
                     /label="ctg1_4666"
                     /locus_tag="ctg1_4666"
                     /protein_end="188"
                     /protein_start="6"
                     /score="230.8"
                     /tool="antismash"
                     /translation="ITGVVLAGGKASRMGGQDKGLMLLNGKPLWQHVADCLCSQVNDVV
                     ISANRNLDIYRQSGLTVIADTLSGYPGPLAGLLSVMQQRTAEWFLFCPCDTPFIPNNLV
                     ERLVAGRHDAPVVWVHDGDRDHPAVALAHRSLAPQIVDYLASGERRVMVFMRQVGGHSV
                     DFSDMKAAFRNMNTPEDLQ"
     PFAM_domain     7077..7529
                     /aSDomain="NTP_transf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12804.9"
                     /description="MobA-like NTP transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4666_0084"
                     /evalue="9.20E-34"
                     /label="ctg1_4666"
                     /locus_tag="ctg1_4666"
                     /protein_end="159"
                     /protein_start="8"
                     /score="117.2"
                     /tool="antismash"
                     /translation="GVVLAGGKASRMGGQDKGLMLLNGKPLWQHVADCLCSQVNDVVIS
                     ANRNLDIYRQSGLTVIADTLSGYPGPLAGLLSVMQQRTAEWFLFCPCDTPFIPNNLVER
                     LVAGRHDAPVVWVHDGDRDHPAVALAHRSLAPQIVDYLASGERRVMV"
     CDS             7634..8140
                     /locus_tag="ctg1_4667"
                     /transl_table=11
                     /translation="MIPLLAIAAWSGTGKTTLLKKLIPELCQLGIRPGLIKHTHHNMDV
                     DKPGKDSYELRKAGAAQTLVASKQRWALMTETPEEEELDLAFLVSRMDASKLDLVLVEG
                     FKHESVAKILLFRQDAGHAVSELTIDEHTIAVASDIRLNVDVPVLDLNNLQEIVAFIVA
                     WLGTE"
     PFAM_domain     7646..8050
                     /aSDomain="MobB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03205.16"
                     /description="Molybdopterin guanine dinucleotide synthesis
                     protein B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4667_0085"
                     /evalue="2.50E-48"
                     /label="ctg1_4667"
                     /locus_tag="ctg1_4667"
                     /protein_end="139"
                     /protein_start="4"
                     /score="163.5"
                     /tool="antismash"
                     /translation="LAIAAWSGTGKTTLLKKLIPELCQLGIRPGLIKHTHHNMDVDKPG
                     KDSYELRKAGAAQTLVASKQRWALMTETPEEEELDLAFLVSRMDASKLDLVLVEGFKHE
                     SVAKILLFRQDAGHAVSELTIDEHTIAVASD"
     aSDomain        7646..8125
                     /aSDomain="TIGR00176"
                     /aSTool="tigrfam"
                     /description="mobB: molybdopterin-guanine dinucleotide
                     biosynthesis protein B"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_4667_0030"
                     /evalue="1.10E-48"
                     /identifier="TIGR00176"
                     /label="ctg1_4667"
                     /locus_tag="ctg1_4667"
                     /protein_end="164"
                     /protein_start="4"
                     /score="163.2"
                     /tool="antismash"
                     /translation="LAIAAWSGTGKTTLLKKLIPELCQLGIRPGLIKHTHHNMDVDKPG
                     KDSYELRKAGAAQTLVASKQRWALMTETPEEEELDLAFLVSRMDASKLDLVLVEGFKHE
                     SVAKILLFRQDAGHAVSELTIDEHTIAVASDIRLNVDVPVLDLNNLQEIVAFIVAW"
ORIGIN
        1 ctgaatacgc tgaccaacca gaaaagcctg gcacgtactt caaaaacgcc cggccgtact
       61 cagctgatta acctgtttga agtcgccgat ggcaaacgtc tggtcgacct gccgggctat
      121 ggctacgcgc aggttccgga agagatgaaa atcaaatggc agcgtgcgct gggtgaatac
      181 ctggagaagc gtctgtgttt gaaaggatta gtggtgctga tggatatccg ccatccgctg
      241 aaggatctcg accagcagat gatcgaatgg gctgtcgcga gtgagattcc ggtactggta
      301 ctgctgacga aggcggataa gctggcaagc ggtgcgcgca aagcgcagct aaaccaggtt
      361 cgtgaagcgg cgctggcctt taacggcgac gtgcaggttg aagccttttc ttcactgaaa
      421 aaacagggag tcgataagct gcgccagaag ctggacagct ggtttaacga cattccgcca
      481 caggaagaag tcgaggcagc agaagagtaa cccccgcatt tatcccggat agcggcgcgc
      541 tgcgccctgt tccgggctcg ccacatcccg ctgatttaac tcaatatctt ttaaatttat
      601 cgtgacgaaa acttttcttt cgcccaataa aaaacgcccc agtcattact gactggggcg
      661 gctaaaatat tcagccaaat ccgattacgt gaagtaaaag gtctgaaaga tagaacatct
      721 tacctctgta ccctacgaga ttaactctac tcttttttac cccgtacaga aagcactttt
      781 tgtagttttt tttcatttgt tacataacga attctaatgt tcatcacaaa actagataag
      841 ttatgttgct tacttacaaa aaagagcgtt attcatcgga tacttaatga gcttgatccc
      901 agttttcacc gctgccgact tccaccagca atggcacgtc cagagtcgta ctgttttcca
      961 ttaattcatg caccttcttc gataccgcat ccagatcgtc tttatgcact tcaaagacca
     1021 attcatcgtg tacctgcatg atcatacgga cgcgcggttt ctcgctttct aaccatttat
     1081 ccaccgcaat catcgcgcgt ttaatgatgt cggcagcggt tccctgcatc ggggcgttaa
     1141 tcgccgcacg ttcagcacct gcacggcgag cgccgttgct ggatttgatg tccggcagat
     1201 agaggcgacg accatcgagc gtggcaacat agccctgctc tttagcctgc tggcgagtac
     1261 gttccatata gtccagcacg ccaggataac gctcgaagta gaggtccata tatttctggg
     1321 cttctttacg cgggatatta agctggcgag ccaggccgaa ggcgctcatg ccgtaaatca
     1381 ggccgaagtt aatcgcctta gcgctgcgac gctgttcatt actcacgctt tccagcggta
     1441 agccaaatac ctcagccgcg gtggcgcggt ggatatcctt accttcggca aatgctttca
     1501 gcaggccttc atcgcgagac aggtgcgcca taatacgcag ttcgatttgc gagtagtcgg
     1561 cagagacgat gaggtaatct tcaggggcaa taaacgcctg gcgaatacgg cgcccctctt
     1621 cattacgcac cggtatgttc tgcaagtttg gatcggttga ggacaaacgc ccggttgcgg
     1681 tgaccgcctg gtgataggag gtatgaacac ggccagtttt cgggttgatc atcagcggca
     1741 gcttatcggt ataagtcgat ttcagtttcg ccagaccacg atactccaga atcactttcg
     1801 gcagcgggta gtcgagcgcc agctcttcca gcacttcttc cgatgtcgac ggcgcgccgc
     1861 ccggcgtttt cttcagcggc ttgatgccct gcttttcaaa cagaatggtc tgcagctgct
     1921 tcggcgagga gaggttaaac tcttcaccgg caatttcgta agccttttgc tccagctcta
     1981 ccaggcgctt agcaatctcc tgcgagtgcg catgtaatac agcaggatca atcttcacgc
     2041 cgttgcgctc aacgcgtgac agcaccggca ccagcggcat ttcaatctcg ttaaagatgc
     2101 gcagaggtcc ttcatgcttc tgcagcttcg gccacatctt caggtgcagt tggagcgtca
     2161 catcggcgtc ttctgccgca tagcgaccgg cttcttccaa tgcaatctgg ttgaaggtca
     2221 gctggttttt acctttgcca gcaatctctt caaaagtgat cgttttgtgt ttcaaccagc
     2281 ggtcagagag gctgtccata tcatggcggc cgacaacgct atccagcgta taggactcca
     2341 gcatggtgtc ataggcgata ccgcgcagct cgatgccgta gttagcaagg ataccgcggt
     2401 cgtatttcag gttctggcca accttcagca gcttttcgtc ttccagcagc ggcttgagaa
     2461 gttccagtgc gcgttcccgg gagatctggt ctggagcatc gaggtagtca tgcgcaactg
     2521 gcacataggc agcgatgccc ggctcggtcg caaacgacaa gcccaccata ttggcagaga
     2581 tattgtccag gctatcggtt tcggtatcga aagcgaacag cggtgctttt ttcagcttct
     2641 caatccagct taccaacgtg gcttcatcga gaatggtgac atagttttcg gatgacaatg
     2701 tggctgccgt ttcttcaact tcaacctcaa tttcaacgtc ggcggcttta ccagcaggct
     2761 taacggctgg tttcgagccc ttggcctgca tccaggtgcc ggactctaca tcggtgatcc
     2821 agcgcttaaa ttcgtatttt ttgaacagcg ttaacagctc atcggccgca ggctccgcaa
     2881 caatcagctg ctcacagccc agctccagct caacgtccgt tttgatggtt gccagcttat
     2941 aggagaggta ggccagatct ttgttctgct caagcttcgc cgccatggtc ttcgcaccac
     3001 ggaaggttaa cccggcgatt ttttccggtt caccgtagag cgtatccagg ccacccagcc
     3061 cttgcagcag cgcctgcgcg gttttttcac ccacgcccgg cacacccgga atattatccg
     3121 aggagtcgcc catcagcgcg aggaaatcaa taatcagctc cggaggcacg ccgtacttgg
     3181 tcacgacttc atccgggccg agaatggtat tggtcatggt attgataagc gtaatgcccg
     3241 gtgtgacgag ctgcgccata tctttatccc cggtgctgat gagcaccgga cggcccgctt
     3301 tttcggcttc acgcgccagc gtgccgatca cgtcatccgc ttcaacgcca gagacggcca
     3361 acagcggaag tcccatggct ttcaccatcg tgtgcagcgg ttcaatctgc gcacgcagat
     3421 cgtccggcat tggcgggcga tgggatttgt agtcttcaaa caattcgtca cggaaggttt
     3481 ttcccttcgc atcaaatacc acggcggcgt gggttggctg atactggagg atcaggctgc
     3541 gcagcatgtt taacacgccg tacatcgcac ctgtcggctc tcccgcacgg ttcgtcagcg
     3601 gtgggaatgc gtgatatgcc cgatagagat aagaagatcc atcaacgagg atgagagggt
     3661 tttcagggat ctgaaccata atttccgtgc ctgtttatca gattatgggt aaaggatgcc
     3721 acatacggca tgaaaacatg agtttttcgc caaaataacg cgaaaagatt tgcagatcct
     3781 cgcgatcgca cgcaaaacaa attgtggata agtttgtgaa tagttttatt ttactgataa
     3841 caaatgatat gtaaccagcg ataaagtaaa aattacctaa ataatttcaa ttagttaact
     3901 caagatcaag gttagtgaga gcgatctggt ggtaattcac acagtgtgga tagacactat
     3961 gaccattttt ctattccggt aagacccgtc atttggcgcg ttttctgtta aaatcagccc
     4021 cttgtgctct tttatatacg cacgttatat aactaactat ctgaataaac aaactatgtc
     4081 gagattgctc gctgcgataa cgttgcccat cagtatcgca ctcaccattt tattgaccat
     4141 attgtgctca ataccgatta ttctcgccgg cattattaaa ttgattttac cggtaccggt
     4201 gatctggcgt tccgtctcgg tattctgcaa ctttatgatg tactgctggt gtgaagggct
     4261 ggcagcgctg ctgcatctca acccctggct caagtgggat attgaagggc tcgagacgct
     4321 caataaaaag aactggtacc tgcttatctg caaccaccac agctgggcag acatcgtggt
     4381 gctatgcgtg atcttccgca agcatatccc aatgaacaaa tacttcctca agcagcagct
     4441 ggcttgggtg cccttcatgg ggctggcatg ctgggcgctg gatatgccat ttatgcgccg
     4501 ttattcacgc agctatctga ttcgccaccc ggaacgccgc ggtaaagatg tagaaacgac
     4561 tcgccgttcc tgcgagaaat tccgcgcgca cccaacaacc atcgtcaact ttgtcgaagg
     4621 ctcacgcttt acgcctgaaa agcgcctgca aacccgttcg ccctatcaaa acctgctgcc
     4681 gccaaaagct gccggtattg cgatggcgct gaacgtgtta ggcacccagt ttgataagct
     4741 gctcgacgtg acgctctgct acccggaaaa cgataagaca ccgttctacg atatgctcag
     4801 cggtaaactg acgcgcattg tggttcgtgt gaatctgcgt ccgattgacc cggagatgca
     4861 tggtgactac gtgggagata agaactttaa gcgacgcttc cagctatggc tgaatgcgct
     4921 gtgggaagag aaagatcatc agattacaga catcaaagca gaatacaaaa acgccggtca
     4981 ttgaccggcg ttttcttttt ttatttcttc tcaacaagct gttttacggt atcagcatac
     5041 tgagcgacaa agacgtccat attgctggtg tccatgccct gcgggttcag ctggtatttg
     5101 ccgttaacaa acattgctgg cacgccctgc agctgcagat cggctgccgc tttttcctgc
     5161 tgcgcgacca gagatttcac cacgaagctg ttccaggcgg cgtcataatc ttcgcccttc
     5221 acgccagcgt cggtgaagac tttacggata tccgcaacgg tctgcacggt ctgggttttc
     5281 tgtaccgctt caaacatcgg tgcagtaatc tgatcttcaa cgcccagcgc catcgctacc
     5341 gcccacgcct gagtcaggtc tttgcccaat gggcccagga actcaacgtg gtatttgatc
     5401 attttagtgc cttccggcag ctttttcttc acgttgtcag aaacgtgcag aacttcttca
     5461 aactgatagc aatgcgggca gtagaaggag aagaactcca gcacctgcgg ctcacctgca
     5521 accggcttat caatcgtaac gtattgtttg ccgtcggtaa tctgagcagc ggatgcgctg
     5581 aatgccagaa tcatacctgc cagcgcaagc caaacctttt tcataactca ctctctcctg
     5641 actgtgtcga attaatacat tggcgttaac tgaagagggg gttcctgtag aaccttcacc
     5701 tgctctataa aagttgcgat ctgccgatgc cagaaatctt ccccggttaa ccagggaaaa
     5761 tttttcggaa atgcagggtc atcccaacgc ctgataatcc aggcaagata ataaaccaac
     5821 cgcattgcac gtaaaggctc aatcagcgcc aattcgtctg aattaaagct gctgaattct
     5881 tcgtaagcct caacgatggt ttcaagctgc atacgtctct ctgcctgaga gccgttaagc
     5941 aacatccaga gatcttgaac cgcggggccg ttgcgcgcat catcgagatc gacaaacagt
     6001 ggaccatcgc gccagagaat atttccagcg tggcagtcac cgtgtaagcg caaggcatcg
     6061 aaacgcccgt gccatagccc cataaccgca tcgatcaaat cgtcggtcgc tttcaggaaa
     6121 cggtctttta aaccagcagg aatgagcgcc gaatgctcaa agagagctcg cggttcaatg
     6181 agatactctt taacaccaat agaaggacgc gcggtaaagc gggatttgcg gcccgtctgg
     6241 tgcatacgcc caagatagcg cccaacccac tccatctgat ccaggttatc tgattcaaat
     6301 tggcggccac ccatgctcgg gaagacggca aaatagaacc cctcatgcat gagcagagtc
     6361 tgaccattaa ataggatagg tgcagcaacc ggaacctcat cctcgactag ctccagcgca
     6421 aactggtgct cttcaagaat ctgcgcagcc gaccagcgtt ccggacgata gaacttcacc
     6481 accatgcggc ggcgatcttc atcctgaaac tgataaaccc ggttctcata gctgttaaga
     6541 ggggtaagtc cagaatcaac ccggataccc tgctcgaata gggcatcgat gatagtatcc
     6601 gggtggagag tctggaatgt gaaagccttg tcgttcatcc tgacatccga taacgatacg
     6661 aatgattcag gatatcattt cacagtgatt tgagtggctc tgcttacaac cttttactct
     6721 tttattacac cgcgagcgcg tagcagcgcg gttttaaagt cttcttcata atctttctga
     6781 atacccggaa tgaccgcatc tttggccgag tcacgcattt tcagatgata gatcagaata
     6841 tcatccgtta aatcggccaa ttcgccgtca tagcctgact ccttcgccag tttctgcaaa
     6901 aattgcagta aattcagctc aggctctttc tgccaggctg gctggaggag ttcgataact
     6961 tcattcagac gtttacattt catggtcgtg ctccttacgc ttgatggaga cacgttagca
     7021 gggtaaacca cacaataaaa gaggcgatag cggtgaatgc acagagccag ataaccggcg
     7081 tggtattagc aggcggtaaa gcctcaagaa tgggcggtca ggataaagga ttaatgctgc
     7141 ttaacggtaa accattgtgg cagcacgttg cagattgtct gtgttcgcag gtaaatgatg
     7201 tcgtcattag tgctaatcgc aatctggata tctatcggca gagtggatta acggtcattg
     7261 ctgatacgct gtcgggttat ccagggccgc ttgccgggct gttatcggtt atgcagcaga
     7321 gaaccgccga gtggtttctg ttttgcccct gtgatacgcc gtttattccc aataatctcg
     7381 ttgaacgcct ggtggcagga cgtcatgacg cgcccgtcgt ttgggtgcat gatggcgatc
     7441 gcgatcaccc tgcagtggcg cttgcccacc gcagtctcgc cccgcagatc gtagattatc
     7501 ttgctagcgg tgaacgccgc gtgatggtat ttatgcgcca ggttggcggc cattctgtcg
     7561 attttagcga catgaaagcg gcatttcgca acatgaatac gccggaagat ttgcagctca
     7621 atcaggaaaa atcatgattc cattgttggc cattgccgcc tggagcggga cgggaaaaac
     7681 gacgctattg aaaaagctca taccagagct ttgccagctc gggattcgcc ctggcctcat
     7741 caagcatact catcacaata tggatgtcga taagccgggt aaggacagct atgaactccg
     7801 taaggcaggg gcagcacaga ctctggtggc gagtaaacaa cgttgggcac tgatgacgga
     7861 aactccggaa gaagaggagc tcgatctggc ttttctggtg agtaggatgg acgcatcgaa
     7921 gctggatctt gtgctggttg aaggcttcaa gcatgaatcc gtcgccaaaa ttctgctatt
     7981 tcgccaggat gccggacatg cagtgagcga gttgactatc gatgaacata cgattgctgt
     8041 cgccagcgat attcggctaa acgttgatgt gccggtgctg gatttgaata atttgcagga
     8101 aatagtggcg tttattgtgg cgtggttagg gacagaatag taggtaggat aaggcgtttt
     8161 cgccgccatc cggcagcgtg cgccaccgca ctttcctttt ccacacacgc aaaaaagccc
     8221 atccgtcagg atgggcttct tcacttaatt gatgcctggc agttccctac tctcgcatgg
     8281 ggagacccca cactaccatc ggcgctacgg cgtttcactt ctgagttcgg catggggtca
     8341 ggtgggacca ccgcgctaca gccgccaggc aaattctgtt atcagaccgc ttctgcgttc
     8401 tgatgtaatc tgtaatcaag ctgaatatcg atgtcttttt cgccaaaaca tcttcggcgt
     8461 tgtaaggtta agcctcacgg ttcattagta ctggttagct caatgtatcg ctacacttac
     8521 acacccagcc tatcaacgtc gtcgtcttca acgttccttc aggactctta aagagtcagg
     8581 gagaactcat cttggggcaa gtttcgtgct tagatgcttt cagcacttat cttttccgca
     8641 tttagctacc gggcaatgcc attggcatga caacccgaac accagtgatg cgtccactcc
     8701 ggtcctctcg tactaggagc agcccccctc aattctccag cgcccacggc agatagggac
     8761 cgaactgtct cacgacgttc taaacccagc tcgcgtacca ctttaaatgg cgaacagcca
     8821 tacccttggg acctacttca gccccaggat gtgatgagcc gacatcgagg tgccaaacac
     8881 cgccgtcgat atgaactctt gggcggtatc agcctgttat ccccggagta ccttttatcc
     8941 gttgagcgat ggcccttcca tacagaacca ccggatcact aagacctgct ttcgcacctg
     9001 ctcgagccgt cactctcgca gtcaagctag cttatgcctt tgcactaacc tcctgatgtc
     9061 cgaccaggat tagctaacct tcgtgctcct ccgttactct ttaggaggag accgccccag
     9121 tcaaactacc caccagacac tgtccgcaac ccggattacg ggtctacgtt agaacaccag
     9181 ccattaaagg gtggtatttc aaggttggct ccacacgaac tggcgtccgc gcttcaaagc
     9241 ctcccaccta tcctacacat caaggaccag tgttcagtgt caagctatag taaaggttca
     9301 cggggtcttt ccgtcttgcc gcgggtacac tgcatcttca cagcgagttc aatttcactg
     9361 agtctcgggt ggagacagcc tggccatcat tacgccattc gtgcaggtcg gaacttaccc
     9421 gacaaggaat ttcgctacct taggaccgtt atagttacgg ccgccgttta ccggggcttc
     9481 gatcaagagc ttcgcgttgc cgctaacccc atcaattaac cttccggcac cgggcaggcg
     9541 tcacaccgta tacgtccact ttcgtgtttg cacagtgctg tgtttttaat aaacagttgc
     9601 agccagctgg tatcttcgac tgatttcagc tccatgagta aatcacttca cctacatatc
     9661 agcgtgcctt ctcccgaagt tacggcacca ttttgcctag ttccttcacc cgagttctct
     9721 caagcgcctt ggtattctct acctgaccac ctgtgtcggt ttggggtacg atttgatgtt
     9781 acctgatgct tagaggcttt tcctggaagc agggcatttg ttacttcagc accgtagtgc
     9841 ctcgtcatca cacctcagcg ttaaaagaag tccggattta cctaaacttc ccgcctacat
     9901 gcttaaaccg ggacaaccgt cgcccggcta acatagcctt ctccgtcccc ccttcgcagt
     9961 aacaccaagt acaggaatat taacctgttt cccatcgact acgcctttcg gcctcgcctt
    10021 aggggtcgac tcaccctgcc ccgattaacg ttggacagga acccttggtc ttccggcgtg
    10081 cgggtttttc acccgcatta tcgttactta tgtcagcatt cgcacttctg atacctccag
    10141 catccctcac aggacacctt cgcaggctta cagaacgctc ccctacccaa caacacatag
    10201 tgtcgctgcc gcagcttcgg tgcacagttt agccccgtta catcttccgc gcaggccgac
    10261 tcgaccagtg agctattacg ctttctttaa atgatggctg cttctaagcc aacatcctgg
    10321 ctgtctgagc cttcccacat cgtttcccac ttaactgtga ctttgggacc ttagctggcg
    10381 gtctgggttg tttccctctt cacgacggac gttagcaccc gccgtgtgtc tcccgtgata
    10441 acattcttcg gtattcgtag tttgcatcgg gttggtaagt cgggatgacc ccctagccga
    10501 aacagtgctc tacccccgaa gatgagttca cgaggcgcta cctaaatagc tttcggggag
    10561 aaccagctat ctcccggttt gattggcctt tcacccccag ccacaagtca tccgctaatt
    10621 tttc
//
