LOCUS       NZ_CP026363.1          20609 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP026363.1 Brevibacillus agri strain DSM 6348 chromosome,
            complete genome.
ACCESSION   NZ_CP026363
VERSION     NZ_CP026363.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:26:06
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1130001
            Orig. end    :: 1150610
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20609
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1140001:1140610](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10609)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20609
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20609
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             856..2577
                     /locus_tag="ctg1_1067"
                     /transl_table=11
                     /translation="VSHLSDLKKTVLCVLTGALTATSIMVAPFAGASAEKSASSVLAAN
                     AESAVPAPVAKGVQKLVRLLPELSSRKVVYGGDVDGPGVSGVKVSFVRAATGTAQGEDS
                     AIFDRATGNLLQLDLVPAKMAKPAFPTDQQAKTRAQTFLTGLLAGNTYQAREVKKEEGK
                     LTVRMVRKVNNVVFDDAYDSFVSFDDAYDSFVSFDAAGRLVGLRMFDGRLYETVNLAVL
                     PSPQRVISAAQAVGKWKGQRPLELVYLLPEQEQNNQTAARLAYIVKDGVISQEHTGSAL
                     DAFSGKRLAAPVQQAQILNVTGTGEKWSAQTENEARNLLRILFKLESANLPLAVLDEKY
                     DDGQERRFFIWGYFPESVADADKKYHIGSFPVGISQAQKHHIMLETDAKTGRLIRFVYK
                     QADEQWSTAKTDKSRDRKGAEALLRRLVPSGSNQLRLADVGTDKYTTLVADPLIGGVPV
                     YRIGQMKEEGMYTITANAWTGKVEEVIVQRPDNMVFPARAKAINEQGAMERLLQAMPLE
                     LTYIHQKDRQTGAMSWKLGYDLSFRQTRSHCFCGGDVKIDTTLYVDALTGQTVVKE"
     CDS             complement(2645..3577)
                     /locus_tag="ctg1_1068"
                     /transl_table=11
                     /translation="MSDIGTTVKNNPYIQPHMSYQGKKEFTTELDNNAFMKLLLEQLKH
                     QDPMSPMDNSQFIQQTSMMTMVEKITKMATLMEQSNNSMLTLEKYESLIGRTATYSLTT
                     KDEVTGETSTETKEGVLDAVYMDSGKIYFRIAGESTPIPLADIKGLESQGMTGNALDSS
                     VKFMNMIGKEISYKTTKEVDKDGNPATTDDITKVDEIANAVVTGFSMKDGATQFTLDNG
                     MTVKLDQVVGMSVRPDSSVMSNSLQYAQMIGFNITYTEKQTNTDGSTIDNSLNGVIKAV
                     SMKNGVVEFVLTDDKKIALNQITGFEASA"
     PFAM_domain     complement(3344..3520)
                     /aSDomain="FlgD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03963.16"
                     /description="Flagellar hook capping protein - N-terminal
                     region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1068_0001"
                     /evalue="9.10E-16"
                     /label="ctg1_1068"
                     /locus_tag="ctg1_1068"
                     /protein_end="78"
                     /protein_start="19"
                     /score="57.9"
                     /tool="antismash"
                     /translation="YQGKKEFTTELDNNAFMKLLLEQLKHQDPMSPMDNSQFIQQTSMM
                     TMVEKITKMATLME"
     CDS             3756..5732
                     /gene_functions="other (smcogs) SMCOG1122:ATP-dependent RNA
                     helicase (Score: 51.9; E-value: 7.7e-16)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1069"
                     /transl_table=11
                     /translation="MDRFELVSEYQPSGDQPTAIAELVAGLQAGKRHQTLLGATGTGKT
                     YTAAQVIAQVNKPTLVMAHNKTLAAQLCAEFKEFFPNNAVEYFVSYYDYYQPEAYIPQS
                     DTFIEKDSSINDEIDKLRHSATSALFERRDVIIVASVSCIYGLGSPEEYKELLLSLRVG
                     MEKGRDEILHRLVDIQYTRNDINFTRGTFRVRGDVVEIFPASQSEQAIRVEFFGDEIER
                     ITSIDVLTGEILGQRDHVAIFPASHYVTREEKMKLAVQSIEAELEERLAELRAAGKLLE
                     AQRLEQRTRYDIEMMLEMGFCSGIENYSRHLTGLPAGHAPYTLMDYFPEDYLLLIDESH
                     MTLPQVRGMYNGDQARKNVLVEHGFRLPSAKDNRPLRFEEFEQKINQAIYISATPGPYE
                     LEHCPELVQQVIRPTGLVDPTISVRPIKGQIDDLIGEIQATIAKNERVLVTTLTKKMSE
                     DLTDYLKEIGIKVRYLHSDIKTIERMQILRSLRLGEFDVLIGINLLREGLDLPEVSLVA
                     ILDADKEGFLRNERSLIQTIGRAARNAEGRVIMYADKMTDSMNSAIRETERRRAIQLAY
                     NEKHGITPQTVKKAVREVIEATKVAEEKADYLPHADFKKMPKKDRLAVIERMEEEMKEA
                     ARNLMFERAAELRDLILELKAEL"
     aSDomain        3762..5720
                     /aSDomain="TIGR00631"
                     /aSTool="tigrfam"
                     /description="uvrb: excinuclease ABC subunit B"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1069_0001"
                     /evalue="0.00E+00"
                     /identifier="TIGR00631"
                     /label="ctg1_1069"
                     /locus_tag="ctg1_1069"
                     /protein_end="655"
                     /protein_start="2"
                     /score="1098.5"
                     /tool="antismash"
                     /translation="RFELVSEYQPSGDQPTAIAELVAGLQAGKRHQTLLGATGTGKTYT
                     AAQVIAQVNKPTLVMAHNKTLAAQLCAEFKEFFPNNAVEYFVSYYDYYQPEAYIPQSDT
                     FIEKDSSINDEIDKLRHSATSALFERRDVIIVASVSCIYGLGSPEEYKELLLSLRVGME
                     KGRDEILHRLVDIQYTRNDINFTRGTFRVRGDVVEIFPASQSEQAIRVEFFGDEIERIT
                     SIDVLTGEILGQRDHVAIFPASHYVTREEKMKLAVQSIEAELEERLAELRAAGKLLEAQ
                     RLEQRTRYDIEMMLEMGFCSGIENYSRHLTGLPAGHAPYTLMDYFPEDYLLLIDESHMT
                     LPQVRGMYNGDQARKNVLVEHGFRLPSAKDNRPLRFEEFEQKINQAIYISATPGPYELE
                     HCPELVQQVIRPTGLVDPTISVRPIKGQIDDLIGEIQATIAKNERVLVTTLTKKMSEDL
                     TDYLKEIGIKVRYLHSDIKTIERMQILRSLRLGEFDVLIGINLLREGLDLPEVSLVAIL
                     DADKEGFLRNERSLIQTIGRAARNAEGRVIMYADKMTDSMNSAIRETERRRAIQLAYNE
                     KHGITPQTVKKAVREVIEATKVAEEKADYLPHADFKKMPKKDRLAVIERMEEEMKEAAR
                     NLMFERAAELRDLILELK"
     PFAM_domain     3789..4169
                     /aSDomain="ResIII"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04851.17"
                     /description="Type III restriction enzyme, res subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1069_0002"
                     /evalue="1.70E-12"
                     /label="ctg1_1069"
                     /locus_tag="ctg1_1069"
                     /protein_end="138"
                     /protein_start="11"
                     /score="47.7"
                     /tool="antismash"
                     /translation="PSGDQPTAIAELVAGLQAGKRHQTLLGATGTGKTYTAAQVIAQVN
                     KPTLVMAHNKTLAAQLCAEFKEFFPNNAVEYFVSYYDYYQPEAYIPQSDTFIEKDSSIN
                     DEIDKLRHSATSALFERRDVIIV"
     PFAM_domain     4227..4499
                     /aSDomain="UvrB_inter"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17757.3"
                     /description="UvrB interaction domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1069_0003"
                     /evalue="2.70E-35"
                     /label="ctg1_1069"
                     /locus_tag="ctg1_1069"
                     /protein_end="248"
                     /protein_start="157"
                     /score="120.5"
                     /tool="antismash"
                     /translation="LSLRVGMEKGRDEILHRLVDIQYTRNDINFTRGTFRVRGDVVEIF
                     PASQSEQAIRVEFFGDEIERITSIDVLTGEILGQRDHVAIFPASHY"
     PFAM_domain     5073..5384
                     /aSDomain="Helicase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00271.33"
                     /description="Helicase conserved C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1069_0004"
                     /evalue="2.10E-18"
                     /label="ctg1_1069"
                     /locus_tag="ctg1_1069"
                     /protein_end="543"
                     /protein_start="439"
                     /score="66.8"
                     /tool="antismash"
                     /translation="TIAKNERVLVTTLTKKMSEDLTDYLKEIGIKVRYLHSDIKTIERM
                     QILRSLRLGEFDVLIGINLLREGLDLPEVSLVAILDADKEGFLRNERSLIQTIGRAARN
                     "
     PFAM_domain     5403..5531
                     /aSDomain="UvrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12344.10"
                     /description="Ultra-violet resistance protein B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1069_0005"
                     /evalue="7.00E-24"
                     /label="ctg1_1069"
                     /locus_tag="ctg1_1069"
                     /protein_end="592"
                     /protein_start="549"
                     /score="83.5"
                     /tool="antismash"
                     /translation="MYADKMTDSMNSAIRETERRRAIQLAYNEKHGITPQTVKKAVR"
     PFAM_domain     5625..5723
                     /aSDomain="UVR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02151.21"
                     /description="UvrB/uvrC motif"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1069_0006"
                     /evalue="3.70E-08"
                     /label="ctg1_1069"
                     /locus_tag="ctg1_1069"
                     /protein_end="656"
                     /protein_start="623"
                     /score="33.0"
                     /tool="antismash"
                     /translation="VIERMEEEMKEAARNLMFERAAELRDLILELKA"
     CDS             5747..8614
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 58.4; E-value:
                     1.5e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1070"
                     /transl_table=11
                     /translation="MPLEHIVVKGARAHNLKNIDVVIPRDKFVVLTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMDKPDVDSIEGLSPAISIDQKTTSRNPRSTVGTVT
                     EIYDYLRLLYARVGRAICPEHGIEIQSQTIEQMVDRLMEYPERTRMQILAPMVQGRKGE
                     HVKLLEDIRKQGFVRVRVNGEITDLSEDIKLEKNKKHNIEVVVDRVVVKPDVQSRLADS
                     LETALRLADGKVIVDVMEQEELLFSEKHACPICGFSIGELEPRIFSFNSPFGACPECDG
                     LGVKLEVDPDMVVPDATKTLHDGAIGAWEPKSSTYYQQLLESACRHFNIRMDIPYEELP
                     PEQVQILMYGSEGEKIQFRYENEFGQVREAVVPFEGVIPNLQRRHLETSSDYIREQIEG
                     FMSQKPCPVCKGHRLRQESLAVKVGERSISELTTLSILDAHQFINELELTEREAKIANL
                     IVKEIKARLNFLIDVGLDYLTLSRAAGTLSGGEAQRIRLATQIGSSLMGVLYILDEPSI
                     GLHQRDNARLIKTLEHMTKLGNTLIVVEHDEDTMMACDYIIDIGPGAGIHGGQVVSAGT
                     PEEVMKDENSLTGAYLSGRKFIPVPLERRKPTDKWIKIEGAKENNLKNVTAKIPLGLFV
                     AVTGVSGSGKSTLINEILQKALSRDLNGAKVKPGEHRRIVGLEHLDKVIDIDQSPIGRT
                     PRSNPATYTGVFDDIRDLFASTNEAKVRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHF
                     LPDVYVPCEVCHGKRYNRETLDVKYKGKSIADVLEMTIEDAVEFFRNLPKIERKLQTIV
                     DVGLGYMKLGQPATTLSGGEAQRVKLASELYRRSTGRTLYILDEPTTGLHTDDIDRLLK
                     VLQRLVENGDTVLVIEHNLDVIKTVDYIVDLGPEGGTRGGQIVGTGTPEEVAQLEGSYT
                     GTYLKPILERDRARTMAKLEQLVSK"
     aSDomain        5762..8515
                     /aSDomain="TIGR00630"
                     /aSTool="tigrfam"
                     /description="uvra: excinuclease ABC subunit A"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1070_0002"
                     /evalue="0.00E+00"
                     /identifier="TIGR00630"
                     /label="ctg1_1070"
                     /locus_tag="ctg1_1070"
                     /protein_end="923"
                     /protein_start="5"
                     /score="1511.9"
                     /tool="antismash"
                     /translation="IVVKGARAHNLKNIDVVIPRDKFVVLTGLSGSGKSSLAFDTIYAE
                     GQRRYVESLSAYARQFLGQMDKPDVDSIEGLSPAISIDQKTTSRNPRSTVGTVTEIYDY
                     LRLLYARVGRAICPEHGIEIQSQTIEQMVDRLMEYPERTRMQILAPMVQGRKGEHVKLL
                     EDIRKQGFVRVRVNGEITDLSEDIKLEKNKKHNIEVVVDRVVVKPDVQSRLADSLETAL
                     RLADGKVIVDVMEQEELLFSEKHACPICGFSIGELEPRIFSFNSPFGACPECDGLGVKL
                     EVDPDMVVPDATKTLHDGAIGAWEPKSSTYYQQLLESACRHFNIRMDIPYEELPPEQVQ
                     ILMYGSEGEKIQFRYENEFGQVREAVVPFEGVIPNLQRRHLETSSDYIREQIEGFMSQK
                     PCPVCKGHRLRQESLAVKVGERSISELTTLSILDAHQFINELELTEREAKIANLIVKEI
                     KARLNFLIDVGLDYLTLSRAAGTLSGGEAQRIRLATQIGSSLMGVLYILDEPSIGLHQR
                     DNARLIKTLEHMTKLGNTLIVVEHDEDTMMACDYIIDIGPGAGIHGGQVVSAGTPEEVM
                     KDENSLTGAYLSGRKFIPVPLERRKPTDKWIKIEGAKENNLKNVTAKIPLGLFVAVTGV
                     SGSGKSTLINEILQKALSRDLNGAKVKPGEHRRIVGLEHLDKVIDIDQSPIGRTPRSNP
                     ATYTGVFDDIRDLFASTNEAKVRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVY
                     VPCEVCHGKRYNRETLDVKYKGKSIADVLEMTIEDAVEFFRNLPKIERKLQTIVDVGLG
                     YMKLGQPATTLSGGEAQRVKLASELYRRSTGRTLYILDEPTTGLHTDDIDRLLKVLQRL
                     VENGDTVLVIEHNLDVIKTVDYIVDLGPEGGTRGGQIVGTGTPEEVA"
     PFAM_domain     6140..6463
                     /aSDomain="UvrA_inter"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17760.3"
                     /description="UvrA interaction domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1070_0007"
                     /evalue="1.90E-42"
                     /label="ctg1_1070"
                     /locus_tag="ctg1_1070"
                     /protein_end="239"
                     /protein_start="131"
                     /score="143.7"
                     /tool="antismash"
                     /translation="QTIEQMVDRLMEYPERTRMQILAPMVQGRKGEHVKLLEDIRKQGF
                     VRVRVNGEITDLSEDIKLEKNKKHNIEVVVDRVVVKPDVQSRLADSLETALRLADGKVI
                     VDVM"
     PFAM_domain     6611..6940
                     /aSDomain="UvrA_DNA-bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17755.3"
                     /description="UvrA DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1070_0008"
                     /evalue="1.10E-35"
                     /label="ctg1_1070"
                     /locus_tag="ctg1_1070"
                     /protein_end="398"
                     /protein_start="288"
                     /score="122.5"
                     /tool="antismash"
                     /translation="DPDMVVPDATKTLHDGAIGAWEPKSSTYYQQLLESACRHFNIRMD
                     IPYEELPPEQVQILMYGSEGEKIQFRYENEFGQVREAVVPFEGVIPNLQRRHLETSSDY
                     IREQIE"
     PFAM_domain     7610..8320
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1070_0009"
                     /evalue="1.60E-10"
                     /label="ctg1_1070"
                     /locus_tag="ctg1_1070"
                     /protein_end="858"
                     /protein_start="621"
                     /score="41.7"
                     /tool="antismash"
                     /translation="LKNVTAKIPLGLFVAVTGVSGSGKSTLINEILQKALSRDLNGAKV
                     KPGEHRRIVGLEHLDKVIDIDQSPIGRTPRSNPATYTGVFDDIRDLFASTNEAKVRGYK
                     KGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGKRYNRETLDVKYKGKSIA
                     DVLEMTIEDAVEFFRNLPKIERKLQTIVDVGLGYMKLGQPATTLSGGEAQRVKLASELY
                     RRSTGRTLYILDEPT"
     CDS             8756..9385
                     /locus_tag="ctg1_1071"
                     /transl_table=11
                     /translation="MEYVAKALAALPADLVEEAKKCFDGQDPAHDWQHNLRVLAMCERI
                     GGEEGADMQVLRLAALLHDVGRAEERQTGECHAEISARVAGKWLRERGMDEERIARVQS
                     AILAHRFRKERPPVTLEEKILFDADKLDSIGAIGVARVFAYTGVIGGPIQSDDPQQHTP
                     FKEYDWKLQRIKDRLFTKTAQAIAQERHAFMVRFFAQWEREVKGLQ"
     aSDomain        8852..9019
                     /aSDomain="TIGR00277"
                     /aSTool="tigrfam"
                     /description="HDIG: HDIG domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1071_0003"
                     /evalue="5.40E-09"
                     /identifier="TIGR00277"
                     /label="ctg1_1071"
                     /locus_tag="ctg1_1071"
                     /protein_end="88"
                     /protein_start="32"
                     /score="33.8"
                     /tool="antismash"
                     /translation="QHNLRVLAMCERIGGEEGADMQVLRLAALLHDVGRAEERQTGECH
                     AEISARVAGKW"
     PFAM_domain     8852..9151
                     /aSDomain="HD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01966.24"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1071_0010"
                     /evalue="4.90E-16"
                     /label="ctg1_1071"
                     /locus_tag="ctg1_1071"
                     /protein_end="132"
                     /protein_start="32"
                     /score="59.1"
                     /tool="antismash"
                     /translation="QHNLRVLAMCERIGGEEGADMQVLRLAALLHDVGRAEERQTGECH
                     AEISARVAGKWLRERGMDEERIARVQSAILAHRFRKERPPVTLEEKILFDADKLD"
     CDS             9419..9787
                     /locus_tag="ctg1_1072"
                     /transl_table=11
                     /translation="MIRWIIKMLLNGAALLFISKWFASIYVANFTVALWAILILGVVNT
                     LIRPVLMFFTLPLTILTLGLFWFVINAVTFALTAYFIDGFEVGPWPDNIGIVIVAAALM
                     SIFGWLIEMVVGMKKEKR"
     PFAM_domain     9422..9748
                     /aSDomain="Phage_holin_4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04020.15"
                     /description="Mycobacterial 4 TMS phage holin, superfamily
                     IV"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1072_0011"
                     /evalue="3.10E-25"
                     /label="ctg1_1072"
                     /locus_tag="ctg1_1072"
                     /protein_end="110"
                     /protein_start="1"
                     /score="89.0"
                     /tool="antismash"
                     /translation="IRWIIKMLLNGAALLFISKWFASIYVANFTVALWAILILGVVNTL
                     IRPVLMFFTLPLTILTLGLFWFVINAVTFALTAYFIDGFEVGPWPDNIGIVIVAAALMS
                     IFGWL"
     CDS             complement(9852..9995)
                     /locus_tag="ctg1_1073"
                     /transl_table=11
                     /translation="MKKVLSTVCSFFGALSVLSVAGVMKVGFLYEPLPPHMRNEEKSNN
                     QA"
     CDS             complement(10001..10609)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1074"
                     /sec_met_domain="AgrB (E-value: 1.7e-29, bitscore: 100.8,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWTEKLSGKIARSIKTEDSPYTVGQLAHGIELFLLNVINLFFIV
                     LVSAVFNLLGEVFPLLCFFFLLRFFTGGVHFKNPWSCLVATLLLLLIGGAIIKYVSLAS
                     VAVMPLLILLVAGAGTFINYTYAPAKHTYMPDNPTVQKKHRKIAILLIVIGCILSLFLV
                     RYSYKLPMTYILAIIYQSLLLMPVSFRFVSFLEKTFSRG"
     PFAM_domain     complement(10064..10597)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1074_0012"
                     /evalue="9.40E-29"
                     /label="ctg1_1074"
                     /locus_tag="ctg1_1074"
                     /protein_end="182"
                     /protein_start="4"
                     /score="100.2"
                     /tool="antismash"
                     /translation="EKLSGKIARSIKTEDSPYTVGQLAHGIELFLLNVINLFFIVLVSA
                     VFNLLGEVFPLLCFFFLLRFFTGGVHFKNPWSCLVATLLLLLIGGAIIKYVSLASVAVM
                     PLLILLVAGAGTFINYTYAPAKHTYMPDNPTVQKKHRKIAILLIVIGCILSLFLVRYSY
                     KLPMTYILAIIYQSL"
     CDS             complement(10625..11968)
                     /locus_tag="ctg1_1075"
                     /transl_table=11
                     /translation="LDFLLRFLLVDIPEAFLLLTISLALFNLSVFEKKKQAILFSLLFA
                     LTGELLTLLEVLYQPKVILMFLCMTAYLILLYRFNILKSVFMGTIALVVMILAESIILA
                     IFNSQQLFLEEILSTTMLAVFARLFYLGVFLTIAIVLRTTKFDIHQLFQHNRLNRYLFL
                     LILLGSVEFLLILFMNTSFFLRENNSAILALYTPQFQMFFQLAILALFIVIVVLFRIYL
                     NLTINRVEEETGTPYLNSIQDLFTAVRSIKHDSLNHYTAINGFLKKELHSHAKEYVEQL
                     LKETVLIERSADSSSQVLERIKNPAVASLLQSKMVVCLAERISLTLEIKEISQFSHYKT
                     YDLIKILGNLLDNAIRATSYELEENRYIRLEWGQTENEHFLYIENSGPTIPECQLQEIF
                     QMGYTTKKNGEGGLGLAIVKNVAERYNGNIQVKSADGITSFCISFANR"
     PFAM_domain     complement(10655..10954)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1075_0013"
                     /evalue="2.50E-17"
                     /label="ctg1_1075"
                     /locus_tag="ctg1_1075"
                     /protein_end="438"
                     /protein_start="338"
                     /score="62.7"
                     /tool="antismash"
                     /translation="KTYDLIKILGNLLDNAIRATSYELEENRYIRLEWGQTENEHFLYI
                     ENSGPTIPECQLQEIFQMGYTTKKNGEGGLGLAIVKNVAERYNGNIQVKSADGIT"
     CDS             12218..13153
                     /locus_tag="ctg1_1076"
                     /transl_table=11
                     /translation="MRKTNVSHLVDHFNMTILSGEEGLGREITVTDLSRPGLQLAGYYS
                     YYAEERIQLFGLTEINFFQTLNRDERLERMNFLMQGQTPCFCVTRNQPVPEEMIEASNN
                     WGVPVLQSPLATTTLVGKMTNFLENRLAPTTTIHGVLTDIYGVGVLIMGSSGIGKSEAA
                     LELVKRGHRLVADDAVEIRQTQAGQLSGSAPELIQHLLEIRGVGIINVMTMFGAGAVRN
                     VKNIEMVVQLELWEPHKMYERLGLDEETLKIMDTDIPIITVPVRPGRNLAVIIEVAAMN
                     FRLKRMGYNAAMHFSRKQSNAILEDADSDL"
     PFAM_domain     12230..12598
                     /aSDomain="Hpr_kinase_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02603.18"
                     /description="HPr Serine kinase N terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1076_0014"
                     /evalue="8.70E-37"
                     /label="ctg1_1076"
                     /locus_tag="ctg1_1076"
                     /protein_end="127"
                     /protein_start="4"
                     /score="126.1"
                     /tool="antismash"
                     /translation="NVSHLVDHFNMTILSGEEGLGREITVTDLSRPGLQLAGYYSYYAE
                     ERIQLFGLTEINFFQTLNRDERLERMNFLMQGQTPCFCVTRNQPVPEEMIEASNNWGVP
                     VLQSPLATTTLVGKMTNFL"
     aSDomain        12230..13123
                     /aSDomain="TIGR00679"
                     /aSTool="tigrfam"
                     /description="hpr-ser: HPr(Ser) kinase/phosphatase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1076_0004"
                     /evalue="2.80E-119"
                     /identifier="TIGR00679"
                     /label="ctg1_1076"
                     /locus_tag="ctg1_1076"
                     /protein_end="302"
                     /protein_start="4"
                     /score="395.8"
                     /tool="antismash"
                     /translation="NVSHLVDHFNMTILSGEEGLGREITVTDLSRPGLQLAGYYSYYAE
                     ERIQLFGLTEINFFQTLNRDERLERMNFLMQGQTPCFCVTRNQPVPEEMIEASNNWGVP
                     VLQSPLATTTLVGKMTNFLENRLAPTTTIHGVLTDIYGVGVLIMGSSGIGKSEAALELV
                     KRGHRLVADDAVEIRQTQAGQLSGSAPELIQHLLEIRGVGIINVMTMFGAGAVRNVKNI
                     EMVVQLELWEPHKMYERLGLDEETLKIMDTDIPIITVPVRPGRNLAVIIEVAAMNFRLK
                     RMGYNAAMHFSRKQSNA"
     PFAM_domain     12605..13111
                     /aSDomain="Hpr_kinase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07475.14"
                     /description="HPr Serine kinase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1076_0015"
                     /evalue="6.60E-74"
                     /label="ctg1_1076"
                     /locus_tag="ctg1_1076"
                     /protein_end="298"
                     /protein_start="129"
                     /score="247.2"
                     /tool="antismash"
                     /translation="RLAPTTTIHGVLTDIYGVGVLIMGSSGIGKSEAALELVKRGHRLV
                     ADDAVEIRQTQAGQLSGSAPELIQHLLEIRGVGIINVMTMFGAGAVRNVKNIEMVVQLE
                     LWEPHKMYERLGLDEETLKIMDTDIPIITVPVRPGRNLAVIIEVAAMNFRLKRMGYNAA
                     MHFSRK"
     CDS             13169..13666
                     /locus_tag="ctg1_1077"
                     /transl_table=11
                     /translation="MRKTTRYPVQGPNPLWQMYRTVSFWKVMKNFIVIQLARYTPFPSW
                     KNWMYRTFLRMEVGQETAVALMVMMDTMFPELIKIGKNSVIGYNTTILAHEYLVEEYRL
                     GEVRIGDRVLIGANSTILPGVTIGDGAIVAAGTVVHKDVAPGSFVGGNPMQVIRPGGLE
                     EK"
     PFAM_domain     13487..13585
                     /aSDomain="Hexapep_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14602.8"
                     /description="Hexapeptide repeat of succinyl-transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1077_0016"
                     /evalue="4.60E-13"
                     /label="ctg1_1077"
                     /locus_tag="ctg1_1077"
                     /protein_end="139"
                     /protein_start="106"
                     /score="48.8"
                     /tool="antismash"
                     /translation="VRIGDRVLIGANSTILPGVTIGDGAIVAAGTVV"
     CDS             13969..15144
                     /locus_tag="ctg1_1078"
                     /transl_table=11
                     /translation="MAKPLGFEKPLGMRDILPESLAKQRHLERALRHCIERWGYEEIST
                     PSLEYYDTVGMASATLTDRMFRLLDKQGHTVVLRPDMTTPIARVVSSLYKDVPLPIRLF
                     YQANVFRAQEKEAGRNAEFFQTGIELIGDGSVDADAEAIALAVFCLRAAGVETFRIAIG
                     HVDFVDGLLEDVVAEEDVRQQFRQYLHERDFVGFRQLLETVAIDSAGKKRLDALLRLRG
                     GKSKIAEARELAGDGKAGRAVETIASLWESLEAYGVTEDLLLDFNLIINLNYYTGVVFE
                     GYAADLGSPLLGGGRYDQLLAQFGRSAPATGFAIKMDRLLTVTPSLRGQAPERILLLYT
                     EDRRPEALAKAQQLRADFQVVVTRLVTGKAEIAAESGQGYSKVICMTEQEE"
     PFAM_domain     14002..14928
                     /aSDomain="tRNA-synt_His"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13393.8"
                     /description="Histidyl-tRNA synthetase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1078_0017"
                     /evalue="1.10E-86"
                     /label="ctg1_1078"
                     /locus_tag="ctg1_1078"
                     /protein_end="320"
                     /protein_start="11"
                     /score="291.0"
                     /tool="antismash"
                     /translation="GMRDILPESLAKQRHLERALRHCIERWGYEEISTPSLEYYDTVGM
                     ASATLTDRMFRLLDKQGHTVVLRPDMTTPIARVVSSLYKDVPLPIRLFYQANVFRAQEK
                     EAGRNAEFFQTGIELIGDGSVDADAEAIALAVFCLRAAGVETFRIAIGHVDFVDGLLED
                     VVAEEDVRQQFRQYLHERDFVGFRQLLETVAIDSAGKKRLDALLRLRGGKSKIAEAREL
                     AGDGKAGRAVETIASLWESLEAYGVTEDLLLDFNLIINLNYYTGVVFEGYAADLGSPLL
                     GGGRYDQLLAQFGRSAPATGFAIKMDRL"
     aSDomain        14008..14940
                     /aSDomain="TIGR00443"
                     /aSTool="tigrfam"
                     /description="hisZ_biosyn_reg: ATP
                     phosphoribosyltransferase, regulatory subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1078_0005"
                     /evalue="1.90E-103"
                     /identifier="TIGR00443"
                     /label="ctg1_1078"
                     /locus_tag="ctg1_1078"
                     /protein_end="324"
                     /protein_start="13"
                     /score="343.8"
                     /tool="antismash"
                     /translation="RDILPESLAKQRHLERALRHCIERWGYEEISTPSLEYYDTVGMAS
                     ATLTDRMFRLLDKQGHTVVLRPDMTTPIARVVSSLYKDVPLPIRLFYQANVFRAQEKEA
                     GRNAEFFQTGIELIGDGSVDADAEAIALAVFCLRAAGVETFRIAIGHVDFVDGLLEDVV
                     AEEDVRQQFRQYLHERDFVGFRQLLETVAIDSAGKKRLDALLRLRGGKSKIAEARELAG
                     DGKAGRAVETIASLWESLEAYGVTEDLLLDFNLIINLNYYTGVVFEGYAADLGSPLLGG
                     GRYDQLLAQFGRSAPATGFAIKMDRLLTVT"
     CDS             15148..15795
                     /locus_tag="ctg1_1079"
                     /transl_table=11
                     /translation="MAFFANEQKLTIAMPKGRIFEEAVHFLQQAGLEVTAELQDSRKLV
                     IPVENARLEFILAKPTDVPTYVEYGVADVGVVGKDVLLEEERDVYELLDLQIGYCRMMV
                     AGLPDWKPTEAPRVATKYPKIASRYFREQGQQVEVIKLNGSVELAPMIGLADRIVDIVS
                     TGRTLKENGLVELEHICEITTRLIANRASYRMKSEAVDDIAGKFLEVIPGRK"
     aSDomain        15175..15711
                     /aSDomain="TIGR00070"
                     /aSTool="tigrfam"
                     /description="hisG: ATP phosphoribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1079_0006"
                     /evalue="3.30E-66"
                     /identifier="TIGR00070"
                     /label="ctg1_1079"
                     /locus_tag="ctg1_1079"
                     /protein_end="188"
                     /protein_start="9"
                     /score="220.6"
                     /tool="antismash"
                     /translation="LTIAMPKGRIFEEAVHFLQQAGLEVTAELQDSRKLVIPVENARLE
                     FILAKPTDVPTYVEYGVADVGVVGKDVLLEEERDVYELLDLQIGYCRMMVAGLPDWKPT
                     EAPRVATKYPKIASRYFREQGQQVEVIKLNGSVELAPMIGLADRIVDIVSTGRTLKENG
                     LVELEHICEITTRLIA"
     PFAM_domain     15322..15762
                     /aSDomain="HisG"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01634.20"
                     /description="ATP phosphoribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1079_0018"
                     /evalue="1.20E-52"
                     /label="ctg1_1079"
                     /locus_tag="ctg1_1079"
                     /protein_end="205"
                     /protein_start="58"
                     /score="178.2"
                     /tool="antismash"
                     /translation="KPTDVPTYVEYGVADVGVVGKDVLLEEERDVYELLDLQIGYCRMM
                     VAGLPDWKPTEAPRVATKYPKIASRYFREQGQQVEVIKLNGSVELAPMIGLADRIVDIV
                     STGRTLKENGLVELEHICEITTRLIANRASYRMKSEAVDDIAG"
     CDS             15819..17114
                     /locus_tag="ctg1_1080"
                     /transl_table=11
                     /translation="MRIMEASQFDGKRSVESGTREQQEGVRAILAAVRERKDEALREYT
                     ERFDRVRLETFRVSAAEFAEASEQVSPQVKAALQEAAENIRDYHSRQVRQSWFVTKESG
                     TMLGQLIRPLQRAGLYVPGGTAAYPSSVLMNAIPAKIAGVPEVVITTPPGADGKVNPAI
                     LVAAQIAGVTEIYKVGGAQAIAALTYGTEQIKAVDKIVGPGNIFVALAKREVFGLVSID
                     MVAGPSEIAVLADDTANARYVAADLLSQAEHDPMSAAILVTPSRELAEQVALEVERQLA
                     ELPRQSIAAAAIRDYGAILLVENLDEGFAVINRIAPEHLEIMIAEPFAQLGKVQNAGAI
                     FLGPYSSEPVGDYFAGTNHVIPTNGTARFSSPLSVDDFIKKSSVISYSKDDLVKNGPKI
                     VTLAEQEGLAGHGRAITERLRDFDREKQECDQ"
     PFAM_domain     15873..17075
                     /aSDomain="Histidinol_dh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00815.22"
                     /description="Histidinol dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1080_0019"
                     /evalue="6.90E-176"
                     /label="ctg1_1080"
                     /locus_tag="ctg1_1080"
                     /protein_end="419"
                     /protein_start="18"
                     /score="585.3"
                     /tool="antismash"
                     /translation="TREQQEGVRAILAAVRERKDEALREYTERFDRVRLETFRVSAAEF
                     AEASEQVSPQVKAALQEAAENIRDYHSRQVRQSWFVTKESGTMLGQLIRPLQRAGLYVP
                     GGTAAYPSSVLMNAIPAKIAGVPEVVITTPPGADGKVNPAILVAAQIAGVTEIYKVGGA
                     QAIAALTYGTEQIKAVDKIVGPGNIFVALAKREVFGLVSIDMVAGPSEIAVLADDTANA
                     RYVAADLLSQAEHDPMSAAILVTPSRELAEQVALEVERQLAELPRQSIAAAAIRDYGAI
                     LLVENLDEGFAVINRIAPEHLEIMIAEPFAQLGKVQNAGAIFLGPYSSEPVGDYFAGTN
                     HVIPTNGTARFSSPLSVDDFIKKSSVISYSKDDLVKNGPKIVTLAEQEGLAGHGRAITE
                     RL"
     aSDomain        15894..17072
                     /aSDomain="TIGR00069"
                     /aSTool="tigrfam"
                     /description="hisD: histidinol dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1080_0007"
                     /evalue="6.60E-172"
                     /identifier="TIGR00069"
                     /label="ctg1_1080"
                     /locus_tag="ctg1_1080"
                     /protein_end="418"
                     /protein_start="25"
                     /score="570.1"
                     /tool="antismash"
                     /translation="VRAILAAVRERKDEALREYTERFDRVRLETFRVSAAEFAEASEQV
                     SPQVKAALQEAAENIRDYHSRQVRQSWFVTKESGTMLGQLIRPLQRAGLYVPGGTAAYP
                     SSVLMNAIPAKIAGVPEVVITTPPGADGKVNPAILVAAQIAGVTEIYKVGGAQAIAALT
                     YGTEQIKAVDKIVGPGNIFVALAKREVFGLVSIDMVAGPSEIAVLADDTANARYVAADL
                     LSQAEHDPMSAAILVTPSRELAEQVALEVERQLAELPRQSIAAAAIRDYGAILLVENLD
                     EGFAVINRIAPEHLEIMIAEPFAQLGKVQNAGAIFLGPYSSEPVGDYFAGTNHVIPTNG
                     TARFSSPLSVDDFIKKSSVISYSKDDLVKNGPKIVTLAEQEGLAGHGRAITER"
     CDS             17114..17713
                     /locus_tag="ctg1_1081"
                     /transl_table=11
                     /translation="MSDRTIRTAAIERNTNETQIALSFGVDGAGESKQESGVPFLDHML
                     DLFTRHGHFDLTVKAKGDIEIDYHHTVEDIGICLGHCIREALGDKKGIKRYGNAFVPMD
                     DALAQVVIDISNRPHLEYRAAYPTNMVGQFPTELVHEFLWKLALEARINLHVILHYGHN
                     THHMIEAIFKALGRALDEATTIDPRVKGVPSTKGVL"
     PFAM_domain     17222..17650
                     /aSDomain="IGPD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00475.20"
                     /description="Imidazoleglycerol-phosphate dehydratase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1081_0020"
                     /evalue="3.00E-62"
                     /label="ctg1_1081"
                     /locus_tag="ctg1_1081"
                     /protein_end="179"
                     /protein_start="36"
                     /score="209.3"
                     /tool="antismash"
                     /translation="GVPFLDHMLDLFTRHGHFDLTVKAKGDIEIDYHHTVEDIGICLGH
                     CIREALGDKKGIKRYGNAFVPMDDALAQVVIDISNRPHLEYRAAYPTNMVGQFPTELVH
                     EFLWKLALEARINLHVILHYGHNTHHMIEAIFKALGRAL"
     CDS             17715..18329
                     /locus_tag="ctg1_1082"
                     /transl_table=11
                     /translation="MIGIIDYGMGNLYSLSKALERLGYSYEFVSAPDRLQEYSGLILPG
                     VGAFGDAIANIRELGLDRAIDAYVASERPILGICLGMQLLFDKSEEHGENAGLGLIRGE
                     VVRFCGDYKVPHMGWNQLRLRREHPLLEGVREGEYVYFVHSYHVLCKPDVLLATSDYHQ
                     EVTAIVGRGQVYGMQFHPEKSGETGMRLLRNFAVQCEGVLA"
     aSDomain        17718..18302
                     /aSDomain="TIGR01855"
                     /aSTool="tigrfam"
                     /description="IMP_synth_hisH: imidazole glycerol phosphate
                     synthase, glutamine amidotransferase subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1082_0008"
                     /evalue="4.70E-74"
                     /identifier="TIGR01855"
                     /label="ctg1_1082"
                     /locus_tag="ctg1_1082"
                     /protein_end="196"
                     /protein_start="1"
                     /score="246.4"
                     /tool="antismash"
                     /translation="IGIIDYGMGNLYSLSKALERLGYSYEFVSAPDRLQEYSGLILPGV
                     GAFGDAIANIRELGLDRAIDAYVASERPILGICLGMQLLFDKSEEHGENAGLGLIRGEV
                     VRFCGDYKVPHMGWNQLRLRREHPLLEGVREGEYVYFVHSYHVLCKPDVLLATSDYHQE
                     VTAIVGRGQVYGMQFHPEKSGETGMRLLRNFA"
     PFAM_domain     17724..18308
                     /aSDomain="GATase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00117.30"
                     /description="Glutamine amidotransferase class-I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1082_0021"
                     /evalue="2.50E-23"
                     /label="ctg1_1082"
                     /locus_tag="ctg1_1082"
                     /protein_end="198"
                     /protein_start="3"
                     /score="82.9"
                     /tool="antismash"
                     /translation="IIDYGMGNLYSLSKALERLGYSYEFVSAPDRLQEYSGLILPGVGA
                     FGDAIANIRELGLDRAIDAYVASERPILGICLGMQLLFDKSEEHGENAGLGLIRGEVVR
                     FCGDYKVPHMGWNQLRLRREHPLLEGVREGEYVYFVHSYHVLCKPDVLLATSDYHQEVT
                     AIVGRGQVYGMQFHPEKSGETGMRLLRNFAVQ"
     CDS             18326..19075
                     /locus_tag="ctg1_1083"
                     /transl_table=11
                     /translation="VSFIIYPAIDIRGGKCVRLFQGDYAQETVYADSPVAMAQRWVEQG
                     AEWVHLVDLDGAKEGKPANASIIKEIARTVSVPVQVGGGIRTEAQIKDYLDAGVARVIV
                     GTAAIEDEPFTKRILQAYGDKIAIGLDCRNGLVATRGWLETTDVAATELAKRLVAYGAE
                     TFIYTDIARDGTMTGPNVEEIAALAIATGKSVIASGGVSRLDDLLVLAGHAADGVSGAI
                     VGKALYTDAFTLEEALTRMEGREQDVG"
     PFAM_domain     18338..19021
                     /aSDomain="His_biosynth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00977.23"
                     /description="Histidine biosynthesis protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1083_0022"
                     /evalue="2.00E-80"
                     /label="ctg1_1083"
                     /locus_tag="ctg1_1083"
                     /protein_end="232"
                     /protein_start="4"
                     /score="269.6"
                     /tool="antismash"
                     /translation="IYPAIDIRGGKCVRLFQGDYAQETVYADSPVAMAQRWVEQGAEWV
                     HLVDLDGAKEGKPANASIIKEIARTVSVPVQVGGGIRTEAQIKDYLDAGVARVIVGTAA
                     IEDEPFTKRILQAYGDKIAIGLDCRNGLVATRGWLETTDVAATELAKRLVAYGAETFIY
                     TDIARDGTMTGPNVEEIAALAIATGKSVIASGGVSRLDDLLVLAGHAADGVSGAIVGKA
                     LYTDAF"
     aSDomain        18338..19036
                     /aSDomain="TIGR00007"
                     /aSTool="tigrfam"
                     /description="TIGR00007:
                     1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylidenea
                     mino]imidazole-4-carboxamide isomera"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1083_0009"
                     /evalue="2.70E-84"
                     /identifier="TIGR00007"
                     /label="ctg1_1083"
                     /locus_tag="ctg1_1083"
                     /protein_end="237"
                     /protein_start="4"
                     /score="280.4"
                     /tool="antismash"
                     /translation="IYPAIDIRGGKCVRLFQGDYAQETVYADSPVAMAQRWVEQGAEWV
                     HLVDLDGAKEGKPANASIIKEIARTVSVPVQVGGGIRTEAQIKDYLDAGVARVIVGTAA
                     IEDEPFTKRILQAYGDKIAIGLDCRNGLVATRGWLETTDVAATELAKRLVAYGAETFIY
                     TDIARDGTMTGPNVEEIAALAIATGKSVIASGGVSRLDDLLVLAGHAADGVSGAIVGKA
                     LYTDAFTLEEA"
     aSDomain        19065..19817
                     /aSDomain="TIGR00735"
                     /aSTool="tigrfam"
                     /description="hisF: imidazoleglycerol phosphate synthase,
                     cyclase subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1084_0010"
                     /evalue="5.70E-116"
                     /identifier="TIGR00735"
                     /label="ctg1_1084"
                     /locus_tag="ctg1_1084"
                     /protein_end="251"
                     /protein_start="0"
                     /score="384.2"
                     /tool="antismash"
                     /translation="MLAKRIIPCLDVKDGRVVKGVQFVGLRDAGDPVELAKKYSEERAD
                     ELVFLDISASHEGRKTMVDVIERTAANITIPFTVGGGINSVEDMKRILRAGADKISLNT
                     AAVLRPELVREGANVFGSQCIVVAIDARSVGEGRWEVYTHGGRNAAGKDVVSWAQEVEA
                     LGAGEILLTSMDDDGEKKGFGIELTRRVSEAVNIPVIASGGAGSKEDFYDVLTAGRADA
                     ALAASIFHYDETSIHSVKEYLQTKGVVVR"
     CDS             19065..19823
                     /locus_tag="ctg1_1084"
                     /transl_table=11
                     /translation="MLAKRIIPCLDVKDGRVVKGVQFVGLRDAGDPVELAKKYSEERAD
                     ELVFLDISASHEGRKTMVDVIERTAANITIPFTVGGGINSVEDMKRILRAGADKISLNT
                     AAVLRPELVREGANVFGSQCIVVAIDARSVGEGRWEVYTHGGRNAAGKDVVSWAQEVEA
                     LGAGEILLTSMDDDGEKKGFGIELTRRVSEAVNIPVIASGGAGSKEDFYDVLTAGRADA
                     ALAASIFHYDETSIHSVKEYLQTKGVVVRP"
     PFAM_domain     19077..19763
                     /aSDomain="His_biosynth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00977.23"
                     /description="Histidine biosynthesis protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1084_0023"
                     /evalue="3.00E-85"
                     /label="ctg1_1084"
                     /locus_tag="ctg1_1084"
                     /protein_end="233"
                     /protein_start="4"
                     /score="285.4"
                     /tool="antismash"
                     /translation="RIIPCLDVKDGRVVKGVQFVGLRDAGDPVELAKKYSEERADELVF
                     LDISASHEGRKTMVDVIERTAANITIPFTVGGGINSVEDMKRILRAGADKISLNTAAVL
                     RPELVREGANVFGSQCIVVAIDARSVGEGRWEVYTHGGRNAAGKDVVSWAQEVEALGAG
                     EILLTSMDDDGEKKGFGIELTRRVSEAVNIPVIASGGAGSKEDFYDVLTAGRADAALAA
                     SIFHYDE"
     CDS             19820..20503
                     /locus_tag="ctg1_1085"
                     /transl_table=11
                     /translation="MTVELLTAENVRFDEKGLIPVIVQDAVSKAVLTLAYMNEESLQRS
                     LETKETWFWSRSRQELWHKGATSGNTQRIVSIQVDCDGDALVVQVVPNGPACHTGAYSC
                     FAGELLAGGQERETAEGSEKAVTAVTSATVDRFAILGELEALIAAREAERPEGSYTTYL
                     FEKGVDKILKKVGEEAAEVIIAAKNRSHEELRYEASDLIFHLLVLLREQKLPLDDVLTE
                     LQRRR"
     PFAM_domain     19919..20134
                     /aSDomain="PRA-CH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01502.20"
                     /description="Phosphoribosyl-AMP cyclohydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1085_0024"
                     /evalue="6.30E-34"
                     /label="ctg1_1085"
                     /locus_tag="ctg1_1085"
                     /protein_end="105"
                     /protein_start="33"
                     /score="115.8"
                     /tool="antismash"
                     /translation="LAYMNEESLQRSLETKETWFWSRSRQELWHKGATSGNTQRIVSIQ
                     VDCDGDALVVQVVPNGPACHTGAYSCF"
     aSDomain        20237..20488
                     /aSDomain="TIGR03188"
                     /aSTool="tigrfam"
                     /description="histidine_hisI: phosphoribosyl-ATP
                     diphosphatase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1085_0011"
                     /evalue="1.30E-32"
                     /identifier="TIGR03188"
                     /label="ctg1_1085"
                     /locus_tag="ctg1_1085"
                     /protein_end="223"
                     /protein_start="139"
                     /score="109.9"
                     /tool="antismash"
                     /translation="LGELEALIAAREAERPEGSYTTYLFEKGVDKILKKVGEEAAEVII
                     AAKNRSHEELRYEASDLIFHLLVLLREQKLPLDDVLTEL"
     PFAM_domain     20240..20497
                     /aSDomain="PRA-PH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01503.19"
                     /description="Phosphoribosyl-ATP pyrophosphohydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1085_0025"
                     /evalue="4.30E-17"
                     /label="ctg1_1085"
                     /locus_tag="ctg1_1085"
                     /protein_end="226"
                     /protein_start="140"
                     /score="62.4"
                     /tool="antismash"
                     /translation="GELEALIAAREAERPEGSYTTYLFEKGVDKILKKVGEEAAEVIIA
                     AKNRSHEELRYEASDLIFHLLVLLREQKLPLDDVLTELQRR"
ORIGIN
        1 tggctgactc cgcttgccct gttcgtccag gtggagccgg ggacgatcag tggcgcgctt
       61 tatccgggtt ggccgttttt ttcaggcgag cttgcttcct tcggactgat gctgctgccg
      121 acggttacgg gtttttcgga tatgacccag acgatgacac cattggaaaa ggtcaagcaa
      181 atttccaaaa accttacctg gtacgcagtc gggcttttgg cgctttgcgc cctgtccgtc
      241 ttgtttgccc cgctcgtttt gctcgctgcc ctgtttgcgt tgttcgggca tgaagcgttg
      301 tttttctgga gccagtggaa agaaaggaag cgttctcctt actacatcca gtcttcacgc
      361 ggcatcaagg tcatgggagt catcccgggc acgcgggcag aggagatcgg gattgtgaca
      421 ggagaaatca tcgtgaaggt caacggcatt ccggtgcggg acaaggaaga cttgtacccg
      481 gcgttgcagg ccaatccggc tttttgcaaa atggaagtgc tcacgcgcga aggcgagatg
      541 aagtttgtgc agtgcgctgt ctacgcgggc aatcaccatc agttgggaat catcgtggtg
      601 ccggacgcaa cgactcgcgt atttgtcgat ttgaaacgat ccagcgtcgt cgagcttatc
      661 aagcagaagc tggaaaaact gaatgtcgga gcttgatgta tcgaacgaga gaaggggaga
      721 aggtatgcgc caacggttgc gtgccttctt ttttttggat agacaggttc gataaaaaca
      781 tttttctgaa aagctcgtct gttcgtaaaa cttacgcctg gctggcgcgt ctacctttac
      841 gaggaaatga agggagtgag tcatttgtcc gatctgaaaa aaacggtctt gtgcgttttg
      901 actggggcgt taacggcgac aagcataatg gttgcgccat ttgccggagc aagcgcagaa
      961 aaatcggcca gttctgtact cgcagcgaat gccgagagcg cagtccctgc acctgttgcc
     1021 aaaggggtgc aaaaattggt tcggctgttg ccggaactgt cttcgcgcaa ggtcgtttac
     1081 ggtggcgatg tggatggacc aggtgtcagc ggcgtaaaag tgtcttttgt gcgggcggcc
     1141 accggaacag ctcaggggga ggacagcgcg atttttgacc gagccacagg gaatttgctc
     1201 cagttggacc tcgttcccgc caaaatggca aagccagcat ttccgactga ccagcaagcg
     1261 aaaacgcgag cgcagacttt cctgacaggc ttgcttgctg gaaatacgta tcaggcgaga
     1321 gaagtgaaga aggaagaagg caagctgacg gtcagaatgg ttcgcaaagt gaacaatgtg
     1381 gtgttcgacg atgcgtatga cagctttgtc agcttcgacg atgcgtatga cagctttgtc
     1441 agcttcgacg ccgcggggcg gcttgtcggg ttgcggatgt ttgacgggcg attgtatgaa
     1501 accgtgaatc tggcggtact cccttcgccg cagcgcgtca tttccgcagc gcaagcagtg
     1561 ggcaagtgga agggacaacg cccgctggag ctggtgtact tgctgccgga gcaggagcaa
     1621 aacaatcaga cggcagcgcg tctcgcctat attgtcaagg atggagtcat ttcgcaggag
     1681 cataccggca gtgccttgga cgcgttcagc ggaaaaaggc tggcagcacc agtccagcag
     1741 gcacaaattt tgaacgtgac cgggacaggg gaaaagtgga gcgcgcagac cgagaacgag
     1801 gcccgcaatt tgctgcgcat cctgttcaaa ctcgaatcag ccaatttgcc gcttgccgta
     1861 ttggacgaga agtacgatga cggccaggag cgccgtttct ttatttgggg ttacttcccg
     1921 gagagtgtcg ccgatgcgga caagaaatac cacatcggaa gttttccggt agggatcagc
     1981 caggcccaaa agcaccatat tatgctcgaa accgatgcca agacagggcg gctgattcgt
     2041 tttgtctaca agcaggcaga tgagcagtgg tccaccgcca aaacagacaa gagccgggat
     2101 cgcaaagggg cggaagcgtt gttgcgaaga ctcgtgcctt ccggaagcaa ccagttgagg
     2161 cttgcggatg tcggcaccga caaatatacg acgctggtgg ccgacccgct tatcggcggc
     2221 gttcctgtct accggatcgg gcagatgaaa gaagaaggga tgtacacgat taccgcaaat
     2281 gcgtggacgg gcaaggtcga ggaagtgatc gtacagcgcc cggacaacat ggttttcccc
     2341 gctcgcgcca aggcgatcaa tgaacaggga gcgatggagc gattgctgca agccatgccg
     2401 cttgagctga cctacattca ccaaaaggat cggcaaacag gcgcgatgag ctggaagctt
     2461 ggctatgacc tgtccttccg ccagacccgc tcgcactgtt tttgcggggg cgatgtgaag
     2521 atagatacga cgttgtatgt cgatgcgctt acgggacaga cggtcgtaaa agaataggga
     2581 caagtaaaaa gaaaaagccg cacgctccag agagagcaag tgcggctttt tcgcatagaa
     2641 aggactaggc gctcgcttca aacccggtga tttgattcag cgcaattttt ttgtcatcag
     2701 tcaagacgaa ctccacgacg ccgtttttca tgctgacggc tttaatgaca ccgttcaggc
     2761 tgttgtctat ggtcgagccg tctgtattgg tttgcttttc cgtataggtg atgttgaagc
     2821 cgatcatttg ggcgtactgc agcgaattgc tcatgacgct gctgtccggc ctgacgctca
     2881 tgcccacgac ctgatcgagc ttgaccgtca tgccgttatc gagcgtaaac tgtgtggcgc
     2941 cgtctttcat ggagaagcct gtgacgaccg cgttggcgat ttcatctact ttggtgatgt
     3001 cgtctgtggt cgccggattg ccgtctttgt ctacttcctt ggtcgtcttg tacgagattt
     3061 ccttgccgat catgttcatg aacttcacgc tgctatccag cgcatttccg gtcatgccct
     3121 gcgattccag acctttgatg tccgcgagcg gaatcggggt agactctccg gcgatgcgga
     3181 agtagatttt gccgctgtcc atgtaaacgg cgtcgagcac gccttccttc gtctccgtcg
     3241 aggtttcacc cgtcacctcg tctttggtcg tgagggagta ggtggcggtg cggccgatca
     3301 gcgactcgta cttttccagt gtcagcatgc tgttgttcga ttgctccatc agcgtcgcca
     3361 ttttggtgat tttttccacc atggtcatca tgctcgtctg ctggatgaac tgggagttgt
     3421 ccatcgggga catcgggtcc tgatgcttca actgttccag cagcagcttc atgaaggcgt
     3481 tgttgtcaag ctctgtggtg aactcctttt tgccttgata gctcatatgt ggttgaatat
     3541 aaggattatt tttaacggtg gttccgatat ctgacatgtc gatcctccct gaaggtggcg
     3601 agtctaaccg tacgtgcttg tacactacta cttattatcg gtataatgtg tcgaaggatg
     3661 aagacaaaca tttgttcgaa tttcggctta tcatagccgg aattgtgtta taatggaaat
     3721 agaaacagtt atgcaacgag gagatgaacg agggaatgga ccgttttgaa ttggtatcgg
     3781 agtatcaacc gtccggtgac cagccgaccg cgatcgccga actggtagcg gggcttcagg
     3841 caggcaagcg gcaccagacg ttgctcgggg ccactggtac gggaaaaacc tatacggccg
     3901 cccaggtgat tgcccaggtg aacaagccga cactggtgat ggcgcacaac aagacattgg
     3961 ctgcccagct atgcgcagag ttcaaggagt ttttcccgaa taacgcggtg gaatacttcg
     4021 tcagctacta cgactactac cagccggaag cgtacattcc ccaatcggat acgtttattg
     4081 aaaaagactc cagcatcaac gacgagatcg acaagctgcg tcactcggcg accagtgccc
     4141 tgtttgagcg gcgcgacgtc attattgtgg cgtcggtatc gtgcatctac ggcttgggtt
     4201 cgccggaaga atacaaggag ctgctgctgt cgctgcgcgt cggcatggaa aaaggacgag
     4261 acgagatttt gcatcggctg gtcgacatcc agtacacgcg caacgacatc aactttacgc
     4321 gggggacctt ccgggtgcgc ggagacgtcg tggagatttt tccggcgtca cagagcgagc
     4381 aggcgattcg cgtggagttt ttcggagacg aaattgagcg gatcacctcc attgacgtgc
     4441 tgaccggaga gattttaggg cagcgcgacc acgtagcgat tttccctgcg tcccactatg
     4501 tcacccgcga agaaaaaatg aagctggccg tccaaagcat cgaggcggag ctggaagagc
     4561 ggctggcaga gctgcgcgca gccgggaagc tgctggaagc gcagcggctg gagcagcgga
     4621 cgcgctacga tattgagatg atgctggaga tgggcttttg ctccgggatc gaaaactact
     4681 cgcgccatct gacggggctt ccggcagggc acgctccgta cacgctgatg gattactttc
     4741 cagaggacta cctgctgttg attgacgagt cgcacatgac cttgccgcag gtgcggggga
     4801 tgtacaacgg cgaccaggcg cgcaagaacg tactggtcga gcatggattc cgcctgccgt
     4861 ctgcgaagga taaccgcccg ctgcgattcg aggagtttga gcagaaaatc aaccaggcga
     4921 tatacatctc ggcaacgccc ggcccgtatg agctggagca ctgcccggaa ctggtgcagc
     4981 aggtcattcg cccgacagga ctggtcgacc cgacgatctc ggtgcgcccg atcaaagggc
     5041 aaattgacga tctcatcggg gaaatccagg ctacgattgc caaaaacgaa cgcgtcctcg
     5101 tcacgacatt gacgaaaaaa atgtcggagg acctgaccga ttacttgaaa gaaatcggga
     5161 tcaaggtccg ctacttgcac tccgacatca agacgatcga acggatgcag attttgcgtt
     5221 ccttgcgatt gggcgaattt gacgtgctga tcgggatcaa cctgttgcgg gaaggtctgg
     5281 acttgcccga ggtttcgctt gtcgctattt tggacgccga caaggaaggc ttcctgcgca
     5341 atgagcgctc cctgatccag acgatcgggc gggcagcccg gaacgccgaa gggcgcgtga
     5401 ttatgtacgc ggacaagatg acggactcga tgaactcggc gattcgcgag acggagcgcc
     5461 gccgcgccat ccagctcgcc tacaacgaga agcacggcat caccccgcag acggtgaaaa
     5521 aagctgtgcg cgaagtgatt gaggcgacaa aggtggccga ggaaaaagcg gactatttgc
     5581 cacacgccga tttcaagaag atgccgaaga aagatcgact ggctgtcatc gaacgcatgg
     5641 aagaagaaat gaaggaagcg gcgcgcaacc tcatgttcga gcgtgcggcc gaactgcgtg
     5701 atttgattct ggagctgaag gcggaactct aaggagaggt tttttcatgc cattggaaca
     5761 tattgtcgtc aagggcgcgc gtgcccacaa tctgaaaaac attgatgtag tgattccgag
     5821 ggacaaattc gtcgtattga cgggtttgtc cggctcggga aagtcttccc ttgcttttga
     5881 cacgatttac gcagagggac agcggcgcta cgtggagtct ctctctgcct atgcccgcca
     5941 gttcctcggg cagatggaca agccggatgt ggattcgatt gaagggctgt cgcccgctat
     6001 ttccatcgac cagaagacga cgagccgcaa cccgcgctcc acagtcggca cggtgacgga
     6061 aatctacgac tatttgcgtc ttttgtatgc gcgtgtgggc agagcgatct gtccagagca
     6121 cggcatcgaa attcagtccc agacgatcga gcagatggta gatcgcctga tggagtaccc
     6181 ggagcgcacg agaatgcaaa tcctcgcgcc catggtacag ggacgcaagg gagagcacgt
     6241 caagctgctg gaggacattc gcaagcaggg cttcgtgcgc gtgcgtgtga acggcgaaat
     6301 taccgatttg tccgaggaca tcaagctgga aaaaaacaaa aagcacaaca tcgaagtcgt
     6361 ggtggatcgc gtcgtcgtga agccggatgt gcagtcgcgt ctcgcggact ctttggagac
     6421 ggctttgcgc ctcgcggacg gcaaggtgat cgtcgacgtg atggagcagg aggagctgtt
     6481 gttcagcgag aagcacgcct gcccgatttg cggattttcc atcggcgagc tggagccgcg
     6541 aattttctct ttcaacagtc cgtttggcgc gtgtccggag tgcgacggtt tgggcgtaaa
     6601 gctggaggta gacccggaca tggtcgttcc ggatgcgacc aagacgttgc atgacggcgc
     6661 gattggcgcc tgggagccga agtcgtcgac ttactatcag cagttgctgg aatcggcttg
     6721 ccgccacttt aacattcgca tggacattcc atacgaggag ctgcccccgg agcaagtgca
     6781 gattttgatg tacggcagcg aaggggagaa aatccagttc cgctatgaaa atgagttcgg
     6841 gcaagtcagg gaagcggttg tgccgtttga aggcgtcatt ccgaatctgc aacgccgtca
     6901 tctggaaacc agctcggact acattcgcga gcaaatcgaa ggcttcatga gccaaaaacc
     6961 ttgccctgtc tgcaaagggc accgtttgcg tcaggagagc ctcgctgtga aggttggaga
     7021 gcgcagcatt tccgagctga cgacgctgtc gattctcgat gcacaccagt tcattaatga
     7081 actggagttg accgagcggg aagcgaagat tgccaacctg atcgtgaagg aaatcaaggc
     7141 acggctcaac tttttgatcg acgtcgggct ggattacttg actctgagcc gggcggccgg
     7201 gacattgtcc gggggcgagg cgcagcggat caggctggct acccagatcg gctccagcct
     7261 gatgggcgtc ctctacatcc tcgacgagcc gagcatcggt ctgcaccagc gggataacgc
     7321 ccgcctgatt aagaccctgg agcatatgac caagctgggg aacacgctga tcgtcgtcga
     7381 gcatgacgaa gatacgatga tggcttgcga ctacattatc gacatcgggc ctggtgcggg
     7441 tattcacggt ggccaggtag tgtctgcggg cacgccggaa gaagtgatga aggatgaaaa
     7501 ctcgctcaca ggcgcctatt tgagcggtcg caagttcatt ccggtcccgc tggagcgcag
     7561 aaagcctaca gacaaatgga tcaaaatcga gggcgcgaag gaaaacaacc tgaaaaacgt
     7621 cacagcgaaa attccgctgg gattgttcgt cgctgtgaca ggtgtatcag gctccgggaa
     7681 aagtacgctc atcaacgaga ttttgcaaaa ggcgctgtcg cgcgatctga acggcgccaa
     7741 agtaaagccg ggcgaacacc gccgcatcgt gggactggag catctggaca aagtcattga
     7801 tatcgaccaa tccccaattg gccggacgcc gcgctccaat ccggcgacgt acacaggcgt
     7861 ctttgacgac attcgcgatc tgtttgcctc gacgaacgaa gcgaaggtgc gcggttacaa
     7921 aaaaggtcgc ttcagcttca acgtcaaagg cgggcgctgt gaggcgtgca gcggcgacgg
     7981 gattatcaaa atcgagatgc actttttgcc ggacgtgtac gtgccttgcg aggtgtgcca
     8041 cggcaagcgc tacaaccggg agacgctcga tgtaaaatac aagggcaaga gcatcgctga
     8101 cgtgctggaa atgacgattg aggatgcggt ggagtttttc cgcaatctgc cgaagatcga
     8161 gcgcaagctg caaacgattg tggacgtcgg ccttggctac atgaagctgg gacagcctgc
     8221 aacgactctc tccggcgggg aagcgcagcg cgtcaagctg gcctccgagc tgtatcgccg
     8281 cagcacaggg cgcacgctgt acattttgga tgagccgaca acaggcttgc atacggatga
     8341 catcgaccgt ctgctcaagg tgttgcagcg cctggtggaa aacggcgaca cagtactcgt
     8401 catcgagcac aatctggatg tcatcaaaac ggtcgattac atcgtcgatt tggggccaga
     8461 aggcggtacc cgcggcggac agattgtcgg cacaggtacg ccggaagaag tggcgcaatt
     8521 ggaaggctcg tacacgggaa cgtacttgaa gccgattttg gaaagagata gagcgagaac
     8581 catggccaag ctggaacagt tggtatcgaa gtaaacaaag atggcctccc tggcaaaagc
     8641 aggggggcgt ctttttctgt acaaaacaag ccgggcaaga aaaagggaac cgctaaaagc
     8701 gtggcgaggc tgcgccatgc catgctcatg ctggcaagag acgggggaga agaacatgga
     8761 atacgtggca aaagcgctgg cggccctccc agccgatctg gtggaggaag cgaaaaaatg
     8821 ctttgacggt caagaccctg cacacgattg gcagcataat ttgcgcgtgc tggcaatgtg
     8881 cgagcggatc ggcggcgagg aaggggcgga catgcaggtg ctgcgcctcg ctgctttgct
     8941 gcacgatgtc gggagagcgg aggagcggca gaccggggag tgtcacgcgg aaatcagcgc
     9001 gcgagtagca ggaaaatggc tgcgggagcg cggcatggat gaagaacgga tcgcgcgggt
     9061 acagtccgcg atcctcgccc atcgctttcg caaggagcgt ccgcctgtaa ccctggaaga
     9121 aaaaatcttg ttcgatgcgg acaagctcga ttcaattggc gctattggag ttgccagagt
     9181 ttttgcttat actggggtta ttggagggcc tatccaatcc gacgacccgc agcagcatac
     9241 tccgttcaag gagtacgact ggaagctgca gcgcatcaaa gacaggctgt tcaccaaaac
     9301 ggcccaagcg attgcgcagg aacggcacgc gttcatggtc cgcttttttg cgcagtggga
     9361 gcgggaagtg aaaggactcc agtagacgct ggggaaactg gcggaaggag gaatgaggat
     9421 gatccgctgg ataatcaaaa tgctcctgaa cggagctgcc ttgcttttca ttagcaaatg
     9481 gtttgcgtcc atttatgttg cgaatttcac cgtggcattg tgggccattc tgattttggg
     9541 tgtcgtgaac acgttgattc gtccggtgct aatgtttttt actttgccgc tgacgatcct
     9601 gacgttgggg cttttctggt ttgtcatcaa cgctgtgacg tttgccctga cagcctattt
     9661 cattgacgga ttcgaagtgg gaccgtggcc ggacaatatc ggcatcgtca tcgtggctgc
     9721 cgcgctgatg agtatttttg gctggttgat cgaaatggtt gtcggcatga aaaaagagaa
     9781 aaggtagaaa gcatcaaaaa aaacccgcgg actctttcgg gagagttcgc gggtttgcta
     9841 ttgtggcggg attatgcttg attgttagat ttctcttcgt ttcgcatgtg aggcgggagt
     9901 ggttcgtaca agaaaccgac tttcataaca cctgcgacgc tcaaaacaga cagggcgcca
     9961 aagaaactgc aaacagtgga aagcactttc ttcatgggta tcatcctctc gaaaatgttt
    10021 tttctaggaa agatacaaag cgaaacgaaa caggcatgag aagcagagac tgatagataa
    10081 ttgctagtat gtaagtcata ggtagcttat aggaatatct taccaagaaa agtgagagaa
    10141 tgcaaccaat aactatcagt agaatagcga tttttcgatg ctttttctgg acagttgggt
    10201 tgtctggcat gtatgtatgt ttagctggag cgtatgtata attgataaat gttcctgccc
    10261 ctgcaacgag aaggatgagg agcggcatga cagcaacaga agccagagaa acatacttga
    10321 taatagcacc gccaataagt aagagcagga gtgtcgctac tagacaggac catggatttt
    10381 taaaatgaac gccgcccgtg aaaaaacgga gtagaaaaaa gaaacaaagg agagggaaga
    10441 cttctcctaa taagttgaat accgcagaaa cgagtacgat gaagaaaaga ttgatgacat
    10501 ttagcaaaaa gagttcaatt ccatgcgcca attgtcccac ggtgtatggc gaatcttctg
    10561 tcttaatcga ccgggcaatt tttcctgaca atttttctgt ccaggtcatt cggttgcctc
    10621 cctgctagcg gtttgcaaaa gaaatgcaaa aactggtgat accatcggca gatttgactt
    10681 gaatgttgcc gttgtagcgt tccgccacgt ttttgacgat ggctagtcca agtccgcctt
    10741 ctccattttt cttcgtggta tagcccattt ggaagatttc ctgaagttga cattccggga
    10801 ttgtcggacc gctattttcg atatacagga agtgctcgtt ttctgtttgt ccccattcaa
    10861 ggcgtatgta gcgattttcc tccagttcgt aagaggttgc acgtatggcg ttgtccagca
    10921 gattgcccaa gattttgatt aaatcatatg ttttgtagtg cgagaactgg ctgatctcct
    10981 tgatttccaa cgtgagcgag atacgctcag ccagacaaac taccattttg gattgcagca
    11041 aggaagcaac ggcaggattt ttgatacgct ccaatacttg cgaactggaa tcagcggatc
    11101 tttcaatcag gaccgtttcc tttaacagtt gctctacgta ttctttggcg tggctatgca
    11161 gttctttttt caagaatcca ttgattgctg tgtaatggtt caaagaatcg tgcttgatgg
    11221 agcgaacggc ggtaaagaga tcctgaatgc tgttcaaata aggcgttccg gtttcttctt
    11281 ctacacgatt gatcgtcaaa ttaagataaa tccggaacaa aaccacaatt acgatgaaca
    11341 aagccaaaat ggctaactga aagaacattt gaaactgcgg agtatacagc gcaagaatgg
    11401 ccgagttgtt ctctctcaga aaaaacgacg tgttcataaa tagaatgagc aaaaactcga
    11461 cgcttcccag aagaattaac aggaacaagt aacgatttaa acggttgtgc tgaaatagct
    11521 gatgaatgtc aaatttggtt gttcgcaata cgatagcgat ggttagaaat acgcctagat
    11581 aaaataaacg ggcaaacact gctagcatcg tagtagacaa tatttcttcc aggaataact
    11641 gctgactgtt aaaaatggcg agaataattg attcggcaag aatcatgacg accagtgcga
    11701 tcgttcccat aaataccgat ttgagaatgt taaaccgata taacaggatc aggtacgcag
    11761 tcatgcataa aaacatcaat atcactttcg gttgataaag cacttccagc aaagttagca
    11821 gctcgcctgt tagtgcaaat agcaggctaa atagaatggc ttgtttcttc ttttcgaaca
    11881 ccgacaggtt gaataaagcc aaactaatcg tcagtagcaa gaaggcttcg ggtatgtcta
    11941 cgagtaagaa gcgaagtaaa aaatccaagg tgttgcctcc tctttttgtc cgacattcgg
    12001 agtaaagcag tctatatttg cactttaacc agatttcgcc tgataccaac ctcattttat
    12061 atcttatgaa ataacgcgaa aaatgtaaat gatacgacaa attgcaagct taggcaagtt
    12121 ggggggcgag aggcaaaggt tgtcggaggc aagacggttt cgatacaata gaggcacaca
    12181 accggggacg gatatcccag ataaggggga agctttcatg cgcaagacaa atgtgagcca
    12241 ccttgtggat catttcaata tgacgatttt aagcggagaa gaggggctgg ggcgcgagat
    12301 tacggtgacg gatttgagcc gtccgggctt gcagcttgca ggctactact cctactacgc
    12361 cgaggaacgg attcaactgt ttggcttgac ggaaatcaac tttttccaga cgctgaacag
    12421 ggatgagcga ttggagcgca tgaatttttt gatgcagggg cagacgccgt gtttttgtgt
    12481 gacgcgcaac cagcctgtcc cggaggaaat gatcgaggcc tcgaacaact ggggcgtgcc
    12541 tgtgctgcaa tcgcctttgg cgacgacgac cttggtgggc aaaatgacca acttcctgga
    12601 gaaccgcctg gcgcctacta ccacgattca tggcgtgctg acggatattt acggggtcgg
    12661 cgtcctgatt atgggatcga gcggaatcgg gaaaagcgaa gccgctttgg aactggtcaa
    12721 acgcgggcat cggctggtgg cggatgatgc tgtcgaaatt cgccagacgc aggcaggcca
    12781 gctaagcggc agcgcacctg agctgatcca gcatttgctg gagattcgcg gcgtggggat
    12841 catcaatgtc atgaccatgt tcggagcagg ggctgtccgc aacgtgaaaa atattgagat
    12901 ggtcgtgcaa ctggagctgt gggagccgca caaaatgtac gagcggcttg gactggacga
    12961 agagacgctg aaaatcatgg acacggacat cccgatcatt accgtacccg tgcgaccagg
    13021 gcgaaacctg gccgtcatta tcgaagtggc ggcgatgaac ttccgcctga agcggatggg
    13081 ctacaatgcg gcgatgcatt tctcgcgcaa gcagtcgaac gccattctgg aagatgccga
    13141 ttcagacttg taggacggag agtggcgcat gaggaagaca acacgttatc cggtccaggg
    13201 gccaaacccg ctctggcaaa tgtaccgcac ggtcagcttc tggaaagtca tgaaaaactt
    13261 catcgtcatc cagcttgccc gctacacgcc ttttccgtca tggaaaaact ggatgtaccg
    13321 cacctttttg cggatggagg tcgggcagga aacggcagtg gcgctgatgg tcatgatgga
    13381 cacgatgttt ccggagttga taaaaatcgg caaaaacagt gtaattggct acaatacgac
    13441 cattctcgcc cacgagtatc tcgtggagga ataccggctg ggagaagtgc gcattggtga
    13501 cagggtgctg attggagcca actcgacgat tttgccgggg gtgacgattg gggacggggc
    13561 gatcgtggct gcgggaacgg tggtccacaa ggacgtggcg cccgggtctt ttgtcggcgg
    13621 caacccgatg caagtgattc ggccgggagg gcttgaggaa aaataggctc gcgcgccgct
    13681 ggtcaggctt ttgcgggaga aagaaagaat aaaggaacgg agtccgtttt ggcgggctct
    13741 tttttattgg cttgcagcag agagaagcgg ggctgctggt gaagccgttg gagatgagcg
    13801 gtgtttgcaa gcattgttcg ggtcgcctac agcttataat caagaatttt ccgactattc
    13861 tcatctccgt tgaccgtgag cggtcttcgt ggtaatcttc atcataacac tttagtttgt
    13921 taccatatta gcagagtaaa gcgaaacgga gcaatggagg gaatgacgat ggcgaagccg
    13981 ttgggatttg aaaaaccgct ggggatgcgg gacatattac cggaatcact ggcgaagcaa
    14041 cggcatttgg agcgggcgct gcggcattgt atcgaacggt gggggtacga ggaaatttcc
    14101 acaccgtcgc tggagtatta cgataccgtg ggaatggcga gcgcaacgct gacagatcga
    14161 atgtttcgcc tgttggataa acaggggcat accgttgtgc tgcggccgga catgacgacg
    14221 ccaatcgctc gcgttgtttc ttctttatat aaagatgtac cgctgccgat ccgcctgttt
    14281 tatcaggcca acgtgtttcg cgcccaggag aaggaagctg gccgaaatgc ggagtttttc
    14341 cagacgggga tcgagctgat tggcgacggc tctgtggatg cggatgcgga ggcgatcgcg
    14401 ctggcagttt tttgtttgcg ggcggcaggc gtggagacgt tccgaatcgc gatcgggcac
    14461 gtcgattttg tagacgggct gctggaggac gtggtcgccg aagaggatgt gcgccagcaa
    14521 ttccgccagt atttgcacga gcgcgatttt gtcggcttcc gccaattgct ggagacggtt
    14581 gcgattgact ctgcggggaa aaagcggctg gacgccttgc ttcgtttgcg cggcggaaaa
    14641 agcaaaatcg cggaggcgcg ggagcttgcg ggtgacggaa aagcagggcg ggcggtagaa
    14701 acgattgctt ccttgtggga atcgctggag gcatacgggg ttaccgagga tttgctgttg
    14761 gacttcaatc tgattatcaa tctgaactac tatacaggcg ttgtctttga aggctacgcc
    14821 gccgatctcg gctctccgct gttgggcggc gggcgttacg atcagctttt ggcccagttc
    14881 gggcgctctg cacctgccac cgggtttgcg atcaaaatgg atcggctgct gacggtcacg
    14941 ccgtcgctgc gaggtcaagc gccagaacgc attttgctgc tttatacaga agatcggcgg
    15001 ccggaagcat tggcaaaggc gcagcagttg cgcgcggact tccaggtggt cgtgacccgg
    15061 ctcgtaacgg gaaaagcgga gatagcggca gagagcgggc aaggctacag caaggtgatc
    15121 tgcatgacgg aacaggagga gtaggagatg gcgtttttcg caaatgagca aaagctgacg
    15181 attgccatgc ccaaagggcg aatttttgaa gaggctgtgc actttttgca gcaggcgggt
    15241 ctggaggtaa cggctgaact gcaggattca cgcaagctgg tcatccctgt ggaaaatgcc
    15301 aggctcgaat ttattttggc aaagcctacc gatgtcccga cttatgtgga atacggagtt
    15361 gcggacgtag gcgtggtcgg caaggatgtt ttgctcgaag aagaacggga tgtctacgag
    15421 ctgttggacc tgcagatcgg ctactgccgg atgatggtcg ccggattgcc ggactggaag
    15481 ccgacagaag cgccgagagt ggcgaccaaa tatccgaaga tcgcttcccg ctattttcgc
    15541 gagcaggggc agcaggtgga ggtcatcaag ctgaacggct cggtggagct ggcgccgatg
    15601 atcgggcttg cggacaggat tgtggatatc gtctctaccg gccggacgtt aaaagaaaat
    15661 ggcctggtgg agctggaaca tatttgcgag attacgacgc ggctgattgc caaccgcgcg
    15721 agctaccgga tgaaaagcga agcggtcgat gatattgccg gaaagtttct ggaggttatt
    15781 ccaggcagaa aatagagaga aggaggggga gaaggaccat gcggattatg gaagcgagtc
    15841 agtttgacgg aaagcggtcg gtggagtcgg ggacgagaga gcagcaggaa ggcgtcaggg
    15901 ccattctcgc cgctgttcgg gagcgaaaag acgaagcttt gcgggaatat acagagaggt
    15961 ttgaccgggt gcggctggag acgtttcggg tgagcgcagc ggagtttgcc gaagcgagcg
    16021 agcaagtctc tccgcaggtc aaagcggctt tgcaggaggc ggcggaaaac atacgcgatt
    16081 accatagccg ccaggtgcgc cagtcgtggt ttgtgacgaa ggagagcggc acgatgctgg
    16141 gacagttgat tcgccctttg cagcgcgcgg gactgtatgt gccagggggc acggccgcct
    16201 atccttccag cgtcctgatg aacgcgatcc cggccaaaat cgcaggcgtc cccgaggtgg
    16261 tcatcactac cccgccggga gcggacggca aggtcaatcc ggcgattctc gtagcggcgc
    16321 agatcgcggg ggtgacggag atttacaaag tgggcggagc gcaagccatc gcggcgctca
    16381 cctatggcac ggaacagatc aaggcggtag acaagatcgt cgggccgggc aatatttttg
    16441 tcgcattggc aaagcgcgag gtgttcgggc tggtcagcat tgacatggta gccgggccaa
    16501 gcgaaattgc cgtgctggct gatgacaccg ccaatgcgcg ttatgtcgct gccgatttgc
    16561 tgtcgcaggc ggagcatgat ccgatgtcgg ccgcgatttt ggtcacgcct tcgcgggagt
    16621 tggccgagca ggtggcgctg gaggtagagc ggcagcttgc cgaactgccg cgccagtcga
    16681 ttgctgcagc ggcgattcgg gattacgggg cgattttgct cgtggaaaat ttggacgaag
    16741 ggttcgccgt catcaaccgg atcgctcccg agcatttgga gatcatgatt gcagagcctt
    16801 tcgcacagtt gggcaaggtg caaaacgccg gggcgatttt cctcgggccg tacagctcag
    16861 agcctgtcgg cgattatttt gccggaacca accatgtgat tccgactaac ggcacggcgc
    16921 gtttttcctc gccgctgtcg gtggatgact ttatcaaaaa atccagtgtc atctcttaca
    16981 gcaaggatga cctggtgaaa aacgggccaa aaatcgtgac cctggccgag caggaagggc
    17041 tggcggggca tggacgcgcc ataaccgaga gactgcgcga ctttgatcgc gagaagcagg
    17101 agtgtgacca gtgatgagtg atcgtacaat ccgcacagca gctattgagc gcaatacaaa
    17161 tgagacgcag atcgcccttt cttttggcgt agatggagca ggcgaaagca agcaggagtc
    17221 gggagtgcct tttttggacc acatgcttga cttgttcacc cggcacgggc attttgatct
    17281 gacggtaaaa gcaaaaggag acatcgaaat cgactaccac cacacggtag aggacatcgg
    17341 catctgtctc gggcattgca tccgcgaggc actgggcgac aaaaaaggaa tcaagcgcta
    17401 cggaaacgcc tttgttccga tggatgacgc gctggcgcag gttgtgatcg acattagcaa
    17461 ccggccgcat ctggagtatc gggccgctta tcctacgaac atggtcggcc agtttccgac
    17521 tgagcttgtg catgaatttc tgtggaagct ggcgctcgaa gcgcggatca atctgcatgt
    17581 gatcttgcac tacggccaca atacacacca catgatcgag gctattttca aagcgctggg
    17641 ccgtgctctg gacgaagcga cgacgatcga tccgcgtgta aaaggggtcc cgtctaccaa
    17701 aggggttttg tagaatgatc ggcatcattg attacggcat gggcaatttg tacagcttga
    17761 gcaaggcttt ggagcggctc ggctattcgt atgagttcgt ttctgcgcct gatcggctgc
    17821 aggagtacag cgggctgatt ttgccggggg taggcgcttt tggcgacgcg attgcaaaca
    17881 tcagggagct gggcctggat cgggcgattg acgcatacgt cgcttccgaa cggccgatct
    17941 tgggcatttg cctggggatg cagcttttgt ttgacaaaag cgaggagcac ggggaaaacg
    18001 ccggactcgg cctgattcgc ggtgaagtgg tccgtttttg cggcgactac aaagtgccgc
    18061 acatgggctg gaaccagttg cgtctccggc gggagcatcc gcttctggag ggagtgcgcg
    18121 aaggcgagta cgtttatttt gttcactctt accatgtgct gtgcaagccg gatgtgctgc
    18181 tggcgacgag cgactatcat caggaggtca cggcgattgt cggacgtggc caggtgtacg
    18241 ggatgcagtt ccatccggaa aagagcggag agacggggat gcggctgctg cgcaattttg
    18301 ccgttcaatg cgagggggtt ttggcgtgag ttttatcatt tatccagcta ttgatattcg
    18361 cggtggaaaa tgtgtgcggc tgtttcaagg ggattacgcc caggagacgg tgtatgcgga
    18421 ttcgcctgtt gccatggcac agcgttgggt agagcagggg gccgagtggg tgcacctcgt
    18481 tgatctggac ggggccaagg aaggaaagcc ggccaatgcg tccatcatca aggaaatcgc
    18541 ccgcacagtg tccgtccccg tgcaggttgg cggcggcatt cggacggaag cgcagatcaa
    18601 ggactatttg gatgcaggcg tggcgcgggt gattgtcggc accgccgcga ttgaagacga
    18661 gccttttacg aaacggattt tgcaggcgta cggcgacaaa atcgcgattg gactcgactg
    18721 ccgcaatggc ctggtcgcta cgcgcggctg gctggagaca acggacgtcg cggcgacaga
    18781 gctggcaaag cggctggtgg catacggcgc ggaaacgttt atttataccg atattgcccg
    18841 cgacggcacg atgacagggc cgaatgtcga ggaaatcgca gcactcgcga tagcgacagg
    18901 caagtcggtc attgcctctg gaggcgtgag tcggcttgat gacctgctcg ttttggcagg
    18961 gcatgcagca gacggagtgt ccggcgcgat tgtcggaaaa gctctttaca cggacgcttt
    19021 cacgctggaa gaagcgctga ctcgcatgga gggacgtgag caggatgttg gctaaaagaa
    19081 tcatcccgtg tctcgatgtc aaagacgggc gggttgtaaa aggagtccag tttgtggggc
    19141 tgcgcgacgc cggagatccg gtcgagctgg cgaagaagta cagtgaagag cgtgcggacg
    19201 agctggtgtt cctggatatt tccgcctccc acgaagggcg caagacgatg gtggatgtca
    19261 tcgagcggac ggcggccaac attacgattc cgtttaccgt tggcggcggc atcaacagcg
    19321 tggaggacat gaagcggatt ttgcgcgccg gagcggacaa aatttcgctg aacacagccg
    19381 ctgtgcttcg tcccgagctt gttcgcgagg gggcgaatgt gttcggctcc cagtgcatcg
    19441 tagtcgcgat tgacgccagg tcggtagggg aagggcgctg ggaagtgtac acgcacggcg
    19501 gacgcaacgc tgccggcaaa gatgtcgtta gctgggcgca agaagtggaa gcgctgggag
    19561 caggcgaaat tcttttgacc agcatggatg atgacggcga gaaaaagggc tttgggatcg
    19621 aattgaccag acgcgtctcg gaagcggtaa acattccggt gattgcttct ggtggggcag
    19681 gctcgaagga agacttttac gacgtgctga cagcggggcg ggcagatgcc gctctggcag
    19741 cttctatttt ccattacgat gagacgtcca ttcactcggt gaaagagtat ctccagacca
    19801 aaggagttgt cgtgcggcca tgacagtaga gcttcttaca gcagaaaacg tgcgctttga
    19861 cgaaaaagga ctgattcctg tcattgtaca ggatgcggtg agcaaggctg ttttgacgct
    19921 tgcctatatg aacgaggagt cgttgcagcg atcgcttgag acgaaagaaa cgtggttttg
    19981 gagccgctcg agacaggagc tgtggcacaa aggggcgacg tccgggaata cacagcggat
    20041 tgtttccatt caggtggatt gcgacgggga tgcgctcgtc gtgcaagtcg tgccgaatgg
    20101 accagcctgc catacaggtg cctatagctg ttttgccggg gagcttttgg cagggggaca
    20161 ggagcgggag acagcagagg gcagcgagaa agccgtcaca gccgtgacga gcgcgacagt
    20221 cgaccgattt gcgattctgg gcgaactgga agcgttgatc gctgctcgcg aggccgagcg
    20281 cccggaaggc tcgtacacga cctatttgtt cgagaaaggc gtcgacaaga ttttgaaaaa
    20341 agtcggggaa gaggccgccg aggtgattat cgccgcgaaa aatcgcagcc acgaagaact
    20401 gcgctacgag gcttccgact tgattttcca cctgcttgtc ctgctgcggg agcagaagct
    20461 gccgctggat gatgtgctga ctgagttgca aaggcggcgg tgaggtgctg gtgttgcttg
    20521 cgagaaaacc actctgtgta cagtagagtg gttttttgtt atgattccag tatctgtctt
    20581 ttgaaaggtg tggtgtccat gaaaaaagg
//
