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Overview
1.1
1.2
1.3
1.4
1.5
1.6
1.7

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP013119.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | ectoine | 608,223 | 618,615 | ectoine | Other | 75%
Region 1.2 | terpene | 1,091,874 | 1,113,604 | burkholderic acid | NRP + Polyketide:Modular type I | 13%
Region 1.3 | resorcinol,NRPS | 1,974,123 | 2,050,563 | bacillibactin | NRP:NRP siderophore | 60%
Region 1.4 | betalactone | 2,088,912 | 2,115,321 |
Region 1.5 | phosphonate | 2,295,442 | 2,336,320 |
Region 1.6 | T1PKS | 2,696,181 | 2,740,098 | emulsan | Saccharide | 9%
Region 1.7 | betalactone | 3,851,748 | 3,882,936 | quinolobactin | Other | 26%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | ectoine | 608,223 | 618,615 | ectoine | Other | 75%
Region 1.2 | terpene | 1,091,874 | 1,113,604 | burkholderic acid | NRP + Polyketide:Modular type I | 13%
Region 1.3 | resorcinol,NRPS | 1,974,123 | 2,050,563 | bacillibactin | NRP:NRP siderophore | 60%
Region 1.4 | betalactone | 2,088,912 | 2,115,321 |
Region 1.5 | phosphonate | 2,295,442 | 2,336,320 |
Region 1.6 | T1PKS | 2,696,181 | 2,740,098 | emulsan | Saccharide | 9%
Region 1.7 | betalactone | 3,851,748 | 3,882,936 | quinolobactin | Other | 26%

No secondary metabolite regions were found in these records:
  NZ_CP013143.1

Compact view
NZ_CP013119.1 - Region 1 - ectoine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 608,223 - 618,615 nt. (total: 10,393 nt) Show pHMM detection rules used
ectoine: ectoine_synt

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ectoine | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.41 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000853.1 |  | 0.41 | Other | ectoine | Streptomyces anulatus
BGC0000856.1 |  | 0.41 | Other | ectoine | Methylophaga thalassica
BGC0000852.1 |  | 0.39 | Other | ectoine | Sporosarcina pasteurii
BGC0000857.1 |  | 0.36 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.34 | Other | ectoine | Methylomicrobium kenyense
BGC0000858.1 |  | 0.33 | Other | ectoine | Methylobacter marinus
BGC0000854.1 |  | 0.32 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000860.1 |  | 0.23 | Other | ectoine | Methylarcula marina
BGC0000703.1 |  | 0.14 | Saccharide | kanamycin | Streptomyces kanamyceticus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.72 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000853.1 |  | 0.72 | Other | ectoine | Streptomyces anulatus
BGC0000856.1 |  | 0.72 | Other | ectoine | Methylophaga thalassica
BGC0000852.1 |  | 0.71 | Other | ectoine | Sporosarcina pasteurii
BGC0000857.1 |  | 0.68 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.67 | Other | ectoine | Methylomicrobium kenyense
BGC0000858.1 |  | 0.67 | Other | ectoine | Methylobacter marinus
BGC0000854.1 |  | 0.66 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000860.1 |  | 0.56 | Other | ectoine | Methylarcula marina
BGC0000703.1 |  | 0.43 | Saccharide | kanamycin | Streptomyces kanamyceticus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP013119.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,091,874 - 1,113,604 nt. (total: 21,731 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.33 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000646.1 |  | 0.24 | Terpene | β-carotein | uncultured bacterium
BGC0000656.1 |  | 0.24 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000664.1 |  | 0.24 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000630.1 |  | 0.24 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000643.1 |  | 0.24 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0001227.1 |  | 0.24 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000634.1 |  | 0.24 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000633.1 |  | 0.24 | Terpene | carotenoid | Streptomyces avermitilis
BGC0000640.1 |  | 0.23 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.66 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000646.1 |  | 0.58 | Terpene | β-carotein | uncultured bacterium
BGC0000656.1 |  | 0.57 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000664.1 |  | 0.57 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000630.1 |  | 0.57 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000643.1 |  | 0.57 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0001227.1 |  | 0.57 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000634.1 |  | 0.57 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000633.1 |  | 0.57 | Terpene | carotenoid | Streptomyces avermitilis
BGC0000640.1 |  | 0.57 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP013119.1 - Region 3 - NRPS,resorcinol
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,974,123 - 2,050,563 nt. (total: 76,441 nt) Show pHMM detection rules used
resorcinol: DarB
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | resorcinol | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000513.1 |  |  | 0.38 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0001940.1 |  |  | 0.34 | Polyketide | pyxidicycline A, pyxidicycline B | Pyxidicoccus fallax
BGC0001343.1 |  |  | 0.34 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0000225.1 |  |  | 0.33 | Polyketide | frenolicin B | Streptomyces roseofulvus
BGC0000554.1 |  |  | 0.33 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001615.1 |  |  | 0.32 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0000487.1 |  |  | 0.32 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000519.1 |  |  | 0.32 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0001407.1 |  |  | 0.32 | RiPP | bicereucin | Bacillus cereus SJ1
BGC0001765.1 |  |  | 0.32 | Saccharide | salecan | Agrobacterium tumefaciens

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.66 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001302.1 |  | 0.60 | Other | lomofungin | Streptomyces lomondensis
BGC0001132.1 |  | 0.57 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001833.1 |  | 0.57 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0000426.1 |  | 0.57 | NRP | sevadicin | Paenibacillus larvae
BGC0000225.1 |  | 0.57 | Polyketide | frenolicin B | Streptomyces roseofulvus
BGC0001128.1 |  | 0.57 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758.1 |  | 0.57 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001825.1 |  | 0.57 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001964.1 |  | 0.56 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Cystobacterineae bacterium

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 1974122 - 2050563:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ser)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location 2006639 - 2050563:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ser)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1824: dhb
  Search NORINE for peptide: strict or relaxed
  AMP-binding (34..442): dhb
  NRPSPredictor2: dhb
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      dhb, sal
    Small clusters prediction:
      dhb, sal
    Single AA prediction:
      dhb
  Stachelhaus prediction details:
    Stachelhaus sequence:
      pMPSQGVVNK
    Nearest Stachelhaus code:
      dhb
    Stachelhaus code match:
      90% (moderate)
ctg1_1826: ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (466..851): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHFSLVDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)

NZ_CP013119.1 - Region 4 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,088,912 - 2,115,321 nt. (total: 26,410 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000938.1 |  | 0.21 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000544.1 |  | 0.16 | RiPP | planosporicin | Planomonospora alba
BGC0000410.1 |  | 0.16 | NRP | pseudomonine | Pseudomonas fluorescens
BGC0000537.1 |  | 0.16 | RiPP | nisin U | Streptococcus uberis
BGC0001789.1 |  | 0.16 | RiPP | suicin 90-1330 | Streptococcus suis
BGC0000887.1 |  | 0.16 | Alkaloid | saxitoxin, gonyautoxin 2, gonyautoxin 3, toxin C2, toxin C3, gonyautoxin 5, decarbamoylsaxitoxin, decarbamoylgonyautoxin 2, decarbamoylgonyautoxin 3 | Dolichospermum circinale AWQC131C
BGC0000498.1 |  | 0.15 | RiPP | bovicin HJ50 | Streptococcus equinus
BGC0000561.1 |  | 0.15 | RiPP | thermophilin 1277 | Streptococcus thermophilus
BGC0000547.1 |  | 0.15 | RiPP | salivaricin 9 | Streptococcus salivarius
BGC0000634.1 |  | 0.15 | Terpene | carotenoid | Brevundimonas sp. SD212

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000938.1 |  | 0.53 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000544.1 |  | 0.47 | RiPP | planosporicin | Planomonospora alba
BGC0000410.1 |  | 0.46 | NRP | pseudomonine | Pseudomonas fluorescens
BGC0000537.1 |  | 0.46 | RiPP | nisin U | Streptococcus uberis
BGC0001789.1 |  | 0.46 | RiPP | suicin 90-1330 | Streptococcus suis
BGC0000887.1 |  | 0.46 | Alkaloid | saxitoxin, gonyautoxin 2, gonyautoxin 3, toxin C2, toxin C3, gonyautoxin 5, decarbamoylsaxitoxin, decarbamoylgonyautoxin 2, decarbamoylgonyautoxin 3 | Dolichospermum circinale AWQC131C
BGC0000498.1 |  | 0.46 | RiPP | bovicin HJ50 | Streptococcus equinus
BGC0000561.1 |  | 0.46 | RiPP | thermophilin 1277 | Streptococcus thermophilus
BGC0000547.1 |  | 0.46 | RiPP | salivaricin 9 | Streptococcus salivarius
BGC0000634.1 |  | 0.46 | Terpene | carotenoid | Brevundimonas sp. SD212

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP013119.1 - Region 5 - phosphonate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,295,442 - 2,336,320 nt. (total: 40,879 nt) Show pHMM detection rules used
phosphonate: phosphonates

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | phosphonate | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000897.1 |  | 0.36 | Other | dehydrophos | Streptomyces luridus
BGC0001859.1 |  | 0.26 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0001343.1 |  | 0.23 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0000343.1 |  | 0.22 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000937.1 |  | 0.22 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0002036.1 |  | 0.20 | Other | dehydrofosmidomycin | Streptomyces lavendulae
BGC0000926.1 |  | 0.20 | Other | rhizocticin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001739.1 |  | 0.20 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000874.1 |  | 0.19 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0001895.1 |  | 0.19 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000897.1 |  | 0.69 | Other | dehydrophos | Streptomyces luridus
BGC0001859.1 |  | 0.59 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0001343.1 |  | 0.56 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0000343.1 |  | 0.55 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000937.1 |  | 0.55 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0002036.1 |  | 0.53 | Other | dehydrofosmidomycin | Streptomyces lavendulae
BGC0000926.1 |  | 0.53 | Other | rhizocticin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001739.1 |  | 0.53 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000874.1 |  | 0.51 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0001895.1 |  | 0.51 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP013119.1 - Region 6 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,696,181 - 2,740,098 nt. (total: 43,918 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T1PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001909.1 |  | 0.31 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0001749.1 |  | 0.31 | Polyketide | epipyriculol | Pyricularia oryzae 70-15
BGC0001124.1 |  | 0.30 | Polyketide | pyranonigrin E | Aspergillus niger ATCC 1015
BGC0001340.1 |  | 0.30 | Polyketide | byssochlamic acid | Byssochlamys fulva
BGC0000046.1 |  | 0.29 | Polyketide | depudecin | Alternaria brassicicola
BGC0001067.1 |  | 0.28 | Polyketide, Terpene | fumagillin, β-trans-bergamotene, fumagillol | Aspergillus fumigatus Af293
BGC0001913.1 |  | 0.28 | Polyketide | phomoidride | fungal sp. ATCC 74256
BGC0001697.1 |  | 0.26 | Polyketide | neurosporin A | Neurospora crassa OR74A
BGC0001141.1 |  | 0.23 | Polyketide | 4-epi-15-epi-brefeldin A | Penicillium brefeldianum
BGC0001205.1 |  | 0.23 | Polyketide | communesin A, communesin B, communesin C, communesin D, communesin E, communesin G, communesin H | Penicillium expansum

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001909.1 |  | 0.65 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0001749.1 |  | 0.64 | Polyketide | epipyriculol | Pyricularia oryzae 70-15
BGC0001124.1 |  | 0.64 | Polyketide | pyranonigrin E | Aspergillus niger ATCC 1015
BGC0001340.1 |  | 0.63 | Polyketide | byssochlamic acid | Byssochlamys fulva
BGC0000046.1 |  | 0.63 | Polyketide | depudecin | Alternaria brassicicola
BGC0001067.1 |  | 0.61 | Polyketide, Terpene | fumagillin, β-trans-bergamotene, fumagillol | Aspergillus fumigatus Af293
BGC0001913.1 |  | 0.61 | Polyketide | phomoidride | fungal sp. ATCC 74256
BGC0001697.1 |  | 0.59 | Polyketide | neurosporin A | Neurospora crassa OR74A
BGC0001141.1 |  | 0.57 | Polyketide | 4-epi-15-epi-brefeldin A | Penicillium brefeldianum
BGC0001205.1 |  | 0.57 | Polyketide | communesin A, communesin B, communesin C, communesin D, communesin E, communesin G, communesin H | Penicillium expansum

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 8, location 2696180 - 2740098:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (pk)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_2456: pk
  PKS_AT (557..857): pk
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 79.2%
    Methylmalonyl-CoA: 66.7%
    Propionyl-CoA: 62.5%
  minowa: Methylmalonyl-CoA
  Prediction, score:
    Methylmalonyl-CoA: 99.4
    Malonyl-CoA: 89.6
    Methoxymalonyl-CoA: 78.9
    Ethylmalonyl-CoA: 62.0
    Propionyl-CoA: 51.1
    Isobutyryl-CoA: 49.4
    2-Methylbutyryl-CoA: 40.5
    trans-1,2-CPDA: 34.5
    CHC-CoA: 31.7
    fatty_acid: 22.1
    Acetyl-CoA: 21.8
    inactive: 21.7
    Benzoyl-CoA: 20.1
    3-Methylbutyryl-CoA: 15.2

NZ_CP013119.1 - Region 7 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,851,748 - 3,882,936 nt. (total: 31,189 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001441.1 |  | 0.34 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000585.1 |  | 0.21 | RiPP | microcin C7 | Escherichia coli
BGC0000343.1 |  | 0.20 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001444.1 |  | 0.19 | Other | caboxamycin | Streptomyces sp. NTK 937
BGC0001538.1 |  | 0.19 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0001831.1 |  | 0.19 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000469.1 |  | 0.18 | RiPP | bottromycin A2 | Streptomyces sp. BC16019
BGC0000774.1 |  | 0.17 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0000917.1 |  | 0.17 | Other | molybdenum cofactor | Rhodobacter capsulatus
BGC0001440.1 |  | 0.17 | Other | cystargolide A, cystargolide B | Kitasatospora cystarginea

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001441.1 |  | 0.67 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000585.1 |  | 0.54 | RiPP | microcin C7 | Escherichia coli
BGC0000343.1 |  | 0.53 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001444.1 |  | 0.51 | Other | caboxamycin | Streptomyces sp. NTK 937
BGC0001538.1 |  | 0.51 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0001831.1 |  | 0.51 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000469.1 |  | 0.50 | RiPP | bottromycin A2 | Streptomyces sp. BC16019
BGC0000774.1 |  | 0.49 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0000917.1 |  | 0.48 | Other | molybdenum cofactor | Rhodobacter capsulatus
BGC0001440.1 |  | 0.48 | Other | cystargolide A, cystargolide B | Kitasatospora cystarginea

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names