LOCUS       NZ_CP031252.1          10861 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP031252.1 Neisseria elongata strain M15911 chromosome, complete
            genome.
ACCESSION   NZ_CP031252
VERSION     NZ_CP031252.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:33:16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 244932
            Orig. end    :: 255793
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10861
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[249932:250793](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5861
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10861
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10861
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             1813..2523
                     /locus_tag="ctg1_232"
                     /transl_table=11
                     /translation="MFAVIGGSGLTRIPELEITGRRIVRTPYGLPSAPLLTGRSGGREL
                     VFLARHGLNHTLAPHEINYRANIWALKSLDVVGIIAVSAVTSLNSDWRSGSLVLPDDLI
                     DYTSARSATFFENDNCGVVHTDFTEPYDAALRQTLLEHAAARETVLLPQAVYGCLQGPR
                     TPTRAEMRRLRRDGVDIFGMTGMPEAVLAREVGLPYAHLCGIVAHADDGAAADERSRKS
                     YDAIEQIRRLLADW"
     PFAM_domain     1819..2475
                     /aSDomain="PNP_UDP_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01048.22"
                     /description="Phosphorylase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_232_0001"
                     /evalue="3.20E-36"
                     /label="ctg1_232"
                     /locus_tag="ctg1_232"
                     /protein_end="221"
                     /protein_start="2"
                     /score="124.9"
                     /tool="antismash"
                     /translation="AVIGGSGLTRIPELEITGRRIVRTPYGLPSAPLLTGRSGGRELVF
                     LARHGLNHTLAPHEINYRANIWALKSLDVVGIIAVSAVTSLNSDWRSGSLVLPDDLIDY
                     TSARSATFFENDNCGVVHTDFTEPYDAALRQTLLEHAAARETVLLPQAVYGCLQGPRTP
                     TRAEMRRLRRDGVDIFGMTGMPEAVLAREVGLPYAHLCGIVAHADDGAAADERSRK"
     CDS             2611..3468
                     /locus_tag="ctg1_233"
                     /transl_table=11
                     /translation="MNHATSFSTPPAQNAQAIAWVFGRPVIDLPQDLFIPPDALKVVLG
                     SFQGPLDLLLYLIRKQNIDVLDIPMIKITEQYLHYIAQIEAQQFDLAAEYLLMAAVLIE
                     IKSRLLLPRTAETEDGEEADPRAELVRRLLAYEQMKLAAQGLDALPRAGRDFAWAYLPL
                     EIAAEVRLPEVVLSDLTQAWLAILSRAKHNKSHEIIQEAVSVRAQMSGILRRLQTAPCR
                     FSELFRPSQGPAYVVVTFIALLELAKEGLVRIVQPENYAEIEISLNDAPNEKTAPDAAA
                     AQAE"
     PFAM_domain     2779..3411
                     /aSDomain="SMC_ScpA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02616.16"
                     /description="Segregation and condensation protein ScpA"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_233_0002"
                     /evalue="1.60E-28"
                     /label="ctg1_233"
                     /locus_tag="ctg1_233"
                     /protein_end="267"
                     /protein_start="56"
                     /score="100.4"
                     /tool="antismash"
                     /translation="LIRKQNIDVLDIPMIKITEQYLHYIAQIEAQQFDLAAEYLLMAAV
                     LIEIKSRLLLPRTAETEDGEEADPRAELVRRLLAYEQMKLAAQGLDALPRAGRDFAWAY
                     LPLEIAAEVRLPEVVLSDLTQAWLAILSRAKHNKSHEIIQEAVSVRAQMSGILRRLQTA
                     PCRFSELFRPSQGPAYVVVTFIALLELAKEGLVRIVQPENYAEIEISL"
     CDS             3489..3821
                     /locus_tag="ctg1_234"
                     /transl_table=11
                     /translation="MDTLPFQNEIAARMLVNTEGETIHPDARFFQTANGYWAAWYEGTA
                     AVLPPDAAPEEPCFWVEGAHDIDELAAMLENGEFDDMETFDGEEEEWHEAGHTCGCSCA
                     HGHEAD"
     CDS             4016..4459
                     /locus_tag="ctg1_235"
                     /transl_table=11
                     /translation="MDKTLGLCRSTEDFGKGISMLALRLFAAYEFGEAGLAKWRGENWF
                     ADIRDAFPFPFDLLPAGWSWNLAMGAELVVPVLLVLGLLTRLGALALMILTAVAWYAVH
                     AGNGYNVCDNGYKMAFIYLLLLLPLLLQGAGKYSLDYLLFRKK"
     PFAM_domain     4073..4330
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_235_0003"
                     /evalue="1.20E-18"
                     /label="ctg1_235"
                     /locus_tag="ctg1_235"
                     /protein_end="105"
                     /protein_start="19"
                     /score="67.5"
                     /tool="antismash"
                     /translation="MLALRLFAAYEFGEAGLAKWRGENWFADIRDAFPFPFDLLPAGWS
                     WNLAMGAELVVPVLLVLGLLTRLGALALMILTAVAWYAVHA"
     CDS             4567..4884
                     /locus_tag="ctg1_236"
                     /transl_table=11
                     /translation="MKTTSSLAALAGALALMGTQAAAAADQNAKPAQTVPAKAAAKKAA
                     EGACGEGKCGAAKPAAKGKAAEAKCGAAKSKAAEGKCAAAKKAAPKAAEGACGEGKCGS
                     H"
     CDS             5001..5861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_237"
                     /sec_met_domain="DUF692 (E-value: 3.2e-120, bitscore:
                     397.4, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTLQGAGLGYKRAMAEDFLHLDPAGSPIRFIEVAPENWMRMGG
                     AARRQFDQVAERFPIACHGLSLSLGGQDPLRVDFLKQIKDFIARYRIGFFSEHLSYCGD
                     NGFVYDLLPLPFTWESVRHTAARIRQVQEILEMRIAVENTSYYAHSPLAEMSEVEFLNA
                     VAREADCDIHLDVNNIYVNAFNHKLLAAHDFIDQVDAGRVTYMHMAGHDREGNDLLIDT
                     HGQAVCGDVWELFAYTCRRLPHSVPTLLERDNNLPPFAELEAEVARIARIQQQTEQERH
                     ENHAA"
     PFAM_domain     5019..5822
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_237_0004"
                     /evalue="3.70E-99"
                     /label="ctg1_237"
                     /locus_tag="ctg1_237"
                     /protein_end="274"
                     /protein_start="6"
                     /score="331.3"
                     /tool="antismash"
                     /translation="GAGLGYKRAMAEDFLHLDPAGSPIRFIEVAPENWMRMGGAARRQF
                     DQVAERFPIACHGLSLSLGGQDPLRVDFLKQIKDFIARYRIGFFSEHLSYCGDNGFVYD
                     LLPLPFTWESVRHTAARIRQVQEILEMRIAVENTSYYAHSPLAEMSEVEFLNAVAREAD
                     CDIHLDVNNIYVNAFNHKLLAAHDFIDQVDAGRVTYMHMAGHDREGNDLLIDTHGQAVC
                     GDVWELFAYTCRRLPHSVPTLLERDNNLPPFAELEAEVARIARIQQ"
     CDS             5842..6597
                     /locus_tag="ctg1_238"
                     /transl_table=11
                     /translation="MKTMQPDNGSGRSAAFQTALADYARGAAQAPEGVDIGRLGVYRRL
                     LLNNLKSFIDLCFSASGGFAEAGLWQDLQRRFLLEARPQSPFFNDIPKQFLDYVRSRPE
                     NERPSENILHMMAFETDLLHAETVIQPEAAPQWDENTELRWAEGARLKHYPCDFVSSGL
                     ERIDDAAADVLTWRGNAGKVYYAALDGADLLLLNHFQEAGADTLSGISAQLAALSDGLD
                     ASDWLEETVRSWVEAGVLLPAPAGRNRDL"
     PFAM_domain     5887..6138
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_238_0005"
                     /evalue="7.20E-13"
                     /label="ctg1_238"
                     /locus_tag="ctg1_238"
                     /protein_end="99"
                     /protein_start="15"
                     /score="48.7"
                     /tool="antismash"
                     /translation="FQTALADYARGAAQAPEGVDIGRLGVYRRLLLNNLKSFIDLCFSA
                     SGGFAEAGLWQDLQRRFLLEARPQSPFFNDIPKQFLDYV"
     CDS             6594..7184
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 123.5;
                     E-value: 1.2e-37)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_239"
                     /transl_table=11
                     /translation="MTTPGQDTYGRLLAALRPGLLRFALIQLRDRAQAEDIVQETLAAA
                     WSKLGQFREEADLKTWVTAILKNKIADHFRSGRRTAVSLDSLCEENEAADQAWHSCFDA
                     GGHWLETAAPAAWRPPEDYAEQQDFFRTLENCLGGLPEDTARIFYLREIMGMEVEEICG
                     RFGIGRDNCYVILHRARNSLRRCLQLRWFDIGA"
     aSDomain        6624..7154
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_239_0002"
                     /evalue="1.00E-26"
                     /identifier="TIGR02937"
                     /label="ctg1_239"
                     /locus_tag="ctg1_239"
                     /protein_end="187"
                     /protein_start="10"
                     /score="91.5"
                     /tool="antismash"
                     /translation="RLLAALRPGLLRFALIQLRDRAQAEDIVQETLAAAWSKLGQFREE
                     ADLKTWVTAILKNKIADHFRSGRRTAVSLDSLCEENEAADQAWHSCFDAGGHWLETAAP
                     AAWRPPEDYAEQQDFFRTLENCLGGLPEDTARIFYLREIMGMEVEEICGRFGIGRDNCY
                     VILHRARNSLRRCL"
     PFAM_domain     6627..6830
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_239_0006"
                     /evalue="6.40E-14"
                     /label="ctg1_239"
                     /locus_tag="ctg1_239"
                     /protein_end="79"
                     /protein_start="11"
                     /score="51.6"
                     /tool="antismash"
                     /translation="LLAALRPGLLRFALIQLRDRAQAEDIVQETLAAAWSKLGQFREEA
                     DLKTWVTAILKNKIADHFRSGRR"
     aSDomain        6627..7172
                     /aSDomain="TIGR02943"
                     /aSTool="tigrfam"
                     /description="Sig70_famx1: RNA polymerase sigma-70 factor,
                     TIGR02943 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_239_0001"
                     /evalue="2.50E-62"
                     /identifier="TIGR02943"
                     /label="ctg1_239"
                     /locus_tag="ctg1_239"
                     /protein_end="193"
                     /protein_start="11"
                     /score="208.0"
                     /tool="antismash"
                     /translation="LLAALRPGLLRFALIQLRDRAQAEDIVQETLAAAWSKLGQFREEA
                     DLKTWVTAILKNKIADHFRSGRRTAVSLDSLCEENEAADQAWHSCFDAGGHWLETAAPA
                     AWRPPEDYAEQQDFFRTLENCLGGLPEDTARIFYLREIMGMEVEEICGRFGIGRDNCYV
                     ILHRARNSLRRCLQLRWFD"
     PFAM_domain     6987..7139
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_239_0007"
                     /evalue="1.30E-08"
                     /label="ctg1_239"
                     /locus_tag="ctg1_239"
                     /protein_end="182"
                     /protein_start="131"
                     /score="34.5"
                     /tool="antismash"
                     /translation="TLENCLGGLPEDTARIFYLREIMGMEVEEICGRFGIGRDNCYVIL
                     HRARNS"
     CDS             7195..7377
                     /locus_tag="ctg1_240"
                     /transl_table=11
                     /translation="MFKCREACKLLSEAQDRKLTLRERVLLNFHLAVCPLCRRYRKQLA
                     FLRENLKKWLSDKYS"
     PFAM_domain     7204..7308
                     /aSDomain="zf-HC2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13490.8"
                     /description="Putative zinc-finger"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_240_0008"
                     /evalue="3.80E-05"
                     /label="ctg1_240"
                     /locus_tag="ctg1_240"
                     /protein_end="38"
                     /protein_start="3"
                     /score="23.9"
                     /tool="antismash"
                     /translation="CREACKLLSEAQDRKLTLRERVLLNFHLAVCPLCR"
     CDS             7452..8243
                     /locus_tag="ctg1_241"
                     /transl_table=11
                     /translation="MQTQAVIEHIVRWLHDYAGQARVKGFIVGISGGIDSAVVSALAAR
                     TGLDVLLLEMPIRQQAEQIDRAQQHIADLQSRFANVRSLRVDLTPAFNCFADTVEVSEA
                     EYPAKQLALANSRARLRMLTLYYYGQINGLLVTGTGNKIEDFGVGFFTKYGDGGVDISP
                     IADLTKTQVYRLAESLNIIEAIRKAVPTDGLWDTERTDEQQMGASYPELEWAMDIPADK
                     QPEDFEGRQREVLAIYRRLNRAAQHKIQPIPVCNVPKEWLA"
     aSDomain        7461..8210
                     /aSDomain="TIGR00552"
                     /aSTool="tigrfam"
                     /description="nadE: NAD+ synthetase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_241_0003"
                     /evalue="2.60E-52"
                     /identifier="TIGR00552"
                     /label="ctg1_241"
                     /locus_tag="ctg1_241"
                     /protein_end="253"
                     /protein_start="3"
                     /score="175.5"
                     /tool="antismash"
                     /translation="QAVIEHIVRWLHDYAGQARVKGFIVGISGGIDSAVVSALAARTGL
                     DVLLLEMPIRQQAEQIDRAQQHIADLQSRFANVRSLRVDLTPAFNCFADTVEVSEAEYP
                     AKQLALANSRARLRMLTLYYYGQINGLLVTGTGNKIEDFGVGFFTKYGDGGVDISPIAD
                     LTKTQVYRLAESLNIIEAIRKAVPTDGLWDTERTDEQQMGASYPELEWAMDIPADKQPE
                     DFEGRQREVLAIYRRLNRAAQHKIQPIP"
     PFAM_domain     7470..8195
                     /aSDomain="NAD_synthase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02540.19"
                     /description="NAD synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_241_0009"
                     /evalue="5.00E-48"
                     /label="ctg1_241"
                     /locus_tag="ctg1_241"
                     /protein_end="248"
                     /protein_start="6"
                     /score="163.4"
                     /tool="antismash"
                     /translation="IEHIVRWLHDYAGQARVKGFIVGISGGIDSAVVSALAARTGLDVL
                     LLEMPIRQQAEQIDRAQQHIADLQSRFANVRSLRVDLTPAFNCFADTVEVSEAEYPAKQ
                     LALANSRARLRMLTLYYYGQINGLLVTGTGNKIEDFGVGFFTKYGDGGVDISPIADLTK
                     TQVYRLAESLNIIEAIRKAVPTDGLWDTERTDEQQMGASYPELEWAMDIPADKQPEDFE
                     GRQREVLAIYRRLNRAAQHK"
     CDS             complement(8381..9001)
                     /locus_tag="ctg1_242"
                     /transl_table=11
                     /translation="MPRKYAALFALLLTAPFAQAERFSLKENENSSRYVETEADIKRRT
                     FTEAEEALPPFPAEGTKWFELYVSPTFDKHLLISPDSIHAAEDGTVRYVLNLRSGKGID
                     NISSEALYCAPGSFSSQQGKKHSYKIYAYGDPVNKRWIKARNPQWQELGGAATSNAAVR
                     AVLHDVWCMDGIPSGDGALLERLNIRGGKYEADGRRSDRETKK"
     PFAM_domain     complement(8465..8875)
                     /aSDomain="CNP1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08750.13"
                     /description="CNP1-like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_242_0010"
                     /evalue="3.90E-28"
                     /label="ctg1_242"
                     /locus_tag="ctg1_242"
                     /protein_end="179"
                     /protein_start="42"
                     /score="98.2"
                     /tool="antismash"
                     /translation="RRTFTEAEEALPPFPAEGTKWFELYVSPTFDKHLLISPDSIHAAE
                     DGTVRYVLNLRSGKGIDNISSEALYCAPGSFSSQQGKKHSYKIYAYGDPVNKRWIKARN
                     PQWQELGGAATSNAAVRAVLHDVWCMDGIPSGD"
     CDS             9138..9362
                     /locus_tag="ctg1_243"
                     /transl_table=11
                     /translation="MSEHYLDVTGLKCPLPILRAKKALAALVCGDVLTVDVTDAGAPDD
                     FAAFCRQTGHVLLASEEREGVFRLVIRHK"
     PFAM_domain     9150..9353
                     /aSDomain="TusA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01206.19"
                     /description="Sulfurtransferase TusA"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_243_0011"
                     /evalue="9.80E-20"
                     /label="ctg1_243"
                     /locus_tag="ctg1_243"
                     /protein_end="72"
                     /protein_start="4"
                     /score="70.4"
                     /tool="antismash"
                     /translation="YLDVTGLKCPLPILRAKKALAALVCGDVLTVDVTDAGAPDDFAAF
                     CRQTGHVLLASEEREGVFRLVIR"
     CDS             complement(9449..10267)
                     /locus_tag="ctg1_244"
                     /transl_table=11
                     /translation="MSRRHAFFISDRTGLTSESMGEALLDQFQEVKFKRSTYPFVDTPD
                     KARAMVKIIETAANQTAMRPLVFSSIINEEIRDIIRNSPGLHLSFFDAFLGILEKELGT
                     KARNEVGRNHGIADTARYDARMEAVNFTLNHDDGVSDKDLKDADVILMGVSRSGKTPTC
                     LYLALQYGIRAANYPLTPDDLDKPDLPPMVKQYRNKIYGLTIKPERLADIREERRPNSN
                     YASISTCKQEVADAQAMFRRFDIPFTNTTHKSVEELAASIMQACGLKRRF"
     PFAM_domain     complement(9479..10249)
                     /aSDomain="Kinase-PPPase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03618.16"
                     /description="Kinase/pyrophosphorylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_244_0012"
                     /evalue="2.70E-75"
                     /label="ctg1_244"
                     /locus_tag="ctg1_244"
                     /protein_end="263"
                     /protein_start="6"
                     /score="253.5"
                     /tool="antismash"
                     /translation="FFISDRTGLTSESMGEALLDQFQEVKFKRSTYPFVDTPDKARAMV
                     KIIETAANQTAMRPLVFSSIINEEIRDIIRNSPGLHLSFFDAFLGILEKELGTKARNEV
                     GRNHGIADTARYDARMEAVNFTLNHDDGVSDKDLKDADVILMGVSRSGKTPTCLYLALQ
                     YGIRAANYPLTPDDLDKPDLPPMVKQYRNKIYGLTIKPERLADIREERRPNSNYASIST
                     CKQEVADAQAMFRRFDIPFTNTTHKSVEELAASIM"
ORIGIN
        1 ggtaacgcgg gctttgtcgc gttttttgcg gtgtcccgtg atggcgaagc ggtgcgattc
       61 gtcgcgtacg gtttgcagga ggtgcagggc ggggctgtgc gggggcaggc ggaaggtttc
      121 gccggtgaac gggaggatga gttcttccat gccggctttg cgttcggggc ctttggcgat
      181 gccgaccaag ggaatgtgca gcccgagttc ttcccatacg gatacggcga tgccgatttg
      241 tcctttgccg ccgtcaatca atacgacatc aggccattta acggtctcgc cgttggcttc
      301 ggcttcctgc attttgccgt agcggcgggt gaggacttcg cgcatggcgg cgtagtcgtc
      361 gccgggtttg gcggtggtga tgttgtagcg tcggtattgc gagggttgga tattttgttc
      421 gtcgtacacg acacaggagg cgatggtggc ttcgccttgg gtgtggctga tgtcgaagca
      481 ttcgaggcgg ttgaggtcgt ctgaattcat gttcaagatt tttgccaact cgtcgatgcg
      541 gtgttgctgg ctgctttgtt gcaggcggcg ttgggctatt gccatttgtg cgttttgttc
      601 cgccattttc agccaaactt tgcgttcgcc tatggttttg gtcacgaact gcatttgttt
      661 gccgtgttcg ccctctaagg cttctttcaa tgcgtcgggg acggggaagt tgctgatgat
      721 gatgtcgggt ttgcttttgc ccagatagtg ttgggcaacg aaggcttcgg cgtagtcttg
      781 cccgtttggt tcggggtcgt ttttggtgtc ggggaagaag cttttgtcgc cgacgtgccg
      841 cccgccgcgt atgctgaccc agtgtacgca gacgaggccg tctgaaacgg cgagcgcgag
      901 caggtcgatg tcgttggggt tgttcgggtt tttgctgtcg atgaactggt tgctctgcat
      961 gatgccgagt gcttggattt ggtcgcggta gcgggcggct tcttcaaatt gcaggttggc
     1021 ggcggcggtc tgcattttgt gttgcagggt gcgggtcagt tcgtcggttt tgccgttgag
     1081 gaaggtggcg gcttggcgca cgctgtcgcg gtagtcttct tcgctgatgt gtccgacgca
     1141 gggcgcggtg cagcgtttga tttgatacag caggcaaggg cggtctcggt gttcgaacac
     1201 gctgtcttcg caggtacgca gcataaagac tttttgcagg acttgcatgc tgtcgcgcac
     1261 ggcgttgctg ttgggatagg ggccgaagta ttggttgggc tttttcagcg tgccgcggta
     1321 atacgccatc tgcggatatt gatgcccgct gagcatgagg tagggatagc ttttgtcgtc
     1381 gcggaaaagg atattgtatt tgggcgacag ggctttgatg aagttgtttt cgagaatcag
     1441 ggcttcggct tcggaacgcg tgatggtggt ttcgatgtgg tgaacctgtt tcaccatcaa
     1501 ggcgatgcgc ggggaatggt cgtttttctg gaaatagccg gacacgcgcc gcttgaggtt
     1561 gaccgctttg ccgacgtata agacgctgcc gccttcgtcg aaaaaacggt atacgccggg
     1621 caggttgggc aggtttttga ggaagagggg gatgtcgaag tccgtggtca tggagtgggt
     1681 ggtgttggta tagttttcag acggcctgaa ttatagcagg ccgtctgaaa aggaaaccta
     1741 cggcagatga aaacaaacag ttcggacagc ctgctataat gccgcccttt tacctgccgg
     1801 agcaataaag acatgtttgc cgttatcgga ggcagcggcc tgacccgcat tcccgaactc
     1861 gaaatcaccg gacgcagaat cgtccgcacg ccatacggcc tgcccagcgc gccgctgctc
     1921 accggcagga gcggcggccg cgagctggtg tttttggcgc ggcacggcct gaaccacacg
     1981 ctcgcgccgc acgaaatcaa ttaccgcgcc aatatttggg cgttgaagtc gttggacgtt
     2041 gtcggaatta tcgcggtatc ggcggttacg tcgttaaata gcgattggcg gtcgggctcg
     2101 ctggttttgc ccgacgattt gattgattac accagtgccc gttccgccac cttctttgaa
     2161 aacgacaact gcggcgtagt ccataccgac tttaccgaac cttacgatgc ggctttgcgc
     2221 caaaccctac tcgaacacgc cgccgcgcgc gagaccgtgc tgttgccgca ggcggtatac
     2281 ggctgcctgc aggggccgcg cacgccgacc cgtgccgaaa tgcggcgttt gcggcgggac
     2341 ggcgtagaca tattcggcat gaccggcatg cccgaagcgg tattggcgcg cgaagtcggc
     2401 ctgccctatg cccacctgtg cggcatcgtc gcccatgccg acgacggtgc ggcggcggac
     2461 gaacgcagcc ggaaatccta tgatgccatc gaacaaatcc gccgccttct ggcggattgg
     2521 taaacgggag ccggaaatgg aaggataccc tttgtcgtcc gcaaaggccg tttcagcggg
     2581 gcggaataca tcgtttcaag ctattaaacc atgaatcacg ccacatcttt ttccactccg
     2641 cccgcacaga atgcacaggc catcgcctgg gtgttcggcc ggcccgtaat cgacctgccg
     2701 caagatttgt ttatcccgcc ggacgcgctg aaagtcgtct tgggcagttt tcaagggccg
     2761 ctggacttgc tgctctacct catccgcaag cagaatatcg acgtgctgga tatcccgatg
     2821 attaaaatca ccgagcaata cctgcactac atcgcccaaa tcgaggcgca gcaatttgat
     2881 ttggcggcgg aatacctgct gatggcggcg gtgctgattg aaatcaaatc gcggctgctg
     2941 ctgccgcgta ccgccgaaac ggaagacggc gaagaggccg acccgcgtgc ggaactggtg
     3001 cgccgccttc tggcctacga acaaatgaaa ctggcggcgc agggcttgga cgcgctgccg
     3061 cgtgccggac gggatttcgc ctgggcatac ctgccgctgg aaatcgccgc cgaagtccgc
     3121 ctgcccgaag tcgtcctatc cgacctgacg caggcctggc tggccatcct ctccagggcc
     3181 aaacacaaca aaagccatga gatcatacag gaggccgtgt ccgtccgcgc gcaaatgagc
     3241 ggcatcctgc gccgcctgca aaccgcgccc tgccgttttt ccgaactgtt ccgcccgtcg
     3301 caaggcccgg cctatgtggt cgttaccttt atcgcgcttt tggaactggc gaaagaaggg
     3361 ctggtcagaa tcgttcagcc ggagaattac gccgaaatcg aaatcagcct gaacgacgcg
     3421 ccgaacgaaa aaaccgcgcc cgatgccgca gcggcacagg cggaataaac cgacaaggaa
     3481 acccgaaaat ggatacactg ccgtttcaaa acgaaattgc cgcccggatg ctggtcaata
     3541 ccgaaggcga aaccatacat cccgacgccc gcttttttca gacggccaac ggctattggg
     3601 cggcctggta cgaaggtacg gcggcagtcc tgccgccgga tgccgccccc gaggaaccct
     3661 gtttttgggt ggagggcgcg cacgacatcg acgaactggc agccatgttg gaaaacggcg
     3721 aatttgacga tatggaaacc ttcgacggcg aagaggaaga atggcatgag gcagggcata
     3781 cctgcggttg cagctgcgcg cacgggcatg aagccgattg agtgggcctg caggcaggaa
     3841 ccgcctgtcc gcaccttgaa acggcagcga aggaaatgac ttgccgattt gatttaaatt
     3901 tatttcattt ccattcatcg gcttatagaa aaaactaaaa ttatttccct ttatttgtaa
     3961 gaaacggccg ccttcgccgt ctaagcgtgc atcaagacat cggaggaagt ttcttatgga
     4021 taaaacgctc ggcctttgcc gctcgacgga agatttcggc aaaggcattt caatgttggc
     4081 gttgcggctg tttgccgcct acgaattcgg cgaggcaggc ttggccaaat ggcgcggcga
     4141 aaactggttt gccgatatac gggacgcgtt tccgtttccc ttcgacctgc tgccggcggg
     4201 ttggagctgg aatctggcga tgggggcgga attggtcgta cccgttttgc tggtgttggg
     4261 cctgctgacg cgcctgggtg cgctggcatt gatgatactg accgctgtgg cctggtatgc
     4321 ggtgcacgcg ggcaacggtt acaatgtgtg cgacaacggc tataaaatgg ccttcattta
     4381 cctgctgcta ctgttgcccc tgctgttgca gggcgcggga aagtattcgc tggattacct
     4441 gcttttccgc aaaaaatagc tttcaggccg tctgaaagac ggaaatcttg ctttcagacg
     4501 gccttttaca gcctgccgga ctgtttccgg catattcatt cgtttttaac actcaggagt
     4561 aaacatatga aaaccacttc ttctttggcc gctctggccg gtgcattggc tttgatgggc
     4621 acccaggctg ccgccgctgc cgaccaaaac gcaaaacccg cacaaaccgt tccggccaaa
     4681 gcggcagcga aaaaagcagc tgaaggcgca tgcggcgaag gcaaatgcgg cgcggccaaa
     4741 cccgctgcaa aaggcaaagc agccgaagcc aaatgcggtg ccgccaaaag caaagcggcc
     4801 gaaggcaaat gcgcagccgc caaaaaagcc gcccctaaag cggccgaagg cgcatgcggc
     4861 gaaggcaaat gcggcagcca ctaattcggc cgcataaata aaacgaggcc gtctgaaaag
     4921 gcacaatccg ttttgacaac gttaaaacgc gctttcagac ggccctcctt acaggaacat
     4981 ccgatttcga aaggaacgat atggcaacca cacttcaagg cgcgggcttg ggctacaagc
     5041 gcgcgatggc ggaggatttc ctgcacctcg accccgcagg cagccccatc cgctttatcg
     5101 aagtcgcacc ggaaaactgg atgcggatgg gtggcgcggc gcgcaggcag ttcgaccaag
     5161 tggcggaacg cttccccatc gcctgccacg gcttgtcgct ttccttgggc ggacaagacc
     5221 cgttgcgggt ggatttcctg aaacaaatta aagattttat cgcccgctac cgcatcggct
     5281 ttttttccga gcacctgagc tattgcggcg acaacggttt tgtatacgac cttttgccgc
     5341 tgccgtttac ctgggaatcc gtgcgccaca ccgccgcgcg catccgtcag gtgcaggaaa
     5401 tattggaaat gcggattgcg gtggaaaaca cctcctatta cgcccacagc ccgctggctg
     5461 aaatgagcga agtggaattc ctcaacgccg tcgcacggga agccgactgc gacatccacc
     5521 tcgacgtgaa caacatctac gtcaatgcct tcaaccacaa gctgttggcc gcgcacgact
     5581 tcatcgacca agtggacgcg gggcgcgtta cctatatgca catggccgga cacgaccggg
     5641 aagggaacga cctgctgatt gatactcacg ggcaggccgt ttgcggcgac gtatgggaac
     5701 tcttcgccta cacctgccgc cgcctgccgc acagcgtgcc gaccctgctc gaacgcgaca
     5761 acaacctgcc gccgtttgcc gaactcgaag cggaagtggc acgcatcgca cgaatccaac
     5821 aacaaacgga gcaggagcgt catgaaaacc atgcagcctg acaacggaag cggccgcagc
     5881 gcggcctttc agacggcctt ggccgactat gcgcgcggcg cggcgcaagc ccccgaaggc
     5941 gtggacatcg gacggctcgg cgtctaccgc cgcctgctgc tgaacaacct gaaaagtttc
     6001 atcgacttat gcttcagtgc ttccggcggt ttcgccgaag ccggcctgtg gcaggacctg
     6061 caacggcgtt tcctgctcga agcccgcccg cagtcgccgt ttttcaacga catccccaaa
     6121 cagtttctcg actacgtccg cagcaggccg gaaaacgaaa ggccgtctga aaacatcctg
     6181 cacatgatgg ctttcgaaac cgacctcctg cacgccgaaa ccgtcatcca gcccgaagcc
     6241 gccccgcaat gggacgaaaa cactgaattg cgctgggccg aaggcgcgcg gctgaaacac
     6301 tatccctgcg acttcgtctc ttccggcctc gaacgcatag acgatgcggc cgccgacgtg
     6361 ctcacctggc gcggcaacgc gggcaaagta tattacgccg ccctcgacgg agccgacctg
     6421 ttactgctga accacttcca agaagcgggc gcggacacgc tgtcgggcat ctcggcgcaa
     6481 ctggccgcgc tttcagacgg cctcgacgct tcagattggc tggaagagac cgtccgaagc
     6541 tgggtggaag caggcgtgct gctgcccgcg cctgccgggc ggaatcggga tttatgacca
     6601 cgcccggaca agacacctac ggccgcctgc ttgccgccct gcgccccggc ctcctgcggt
     6661 tcgcactcat ccaactgcgc gaccgggcgc aggcggaaga catcgtgcag gaaacccttg
     6721 ccgccgcttg gagcaagctc ggccaattcc gcgaagaagc cgatttgaaa acctgggtaa
     6781 cggccattct caaaaacaaa atcgccgacc atttccgcag cggcaggcgc accgccgtca
     6841 gcctcgacag cctgtgcgaa gaaaacgaag ccgccgacca agcctggcac tcctgcttcg
     6901 atgccggcgg ccactggctc gaaaccgccg cccccgccgc ctggcggccg ccggaagact
     6961 atgccgaaca gcaggatttt ttccgcacgc tggaaaactg cctcggcggc ctgccggaag
     7021 acaccgcccg catcttctac ctgcgagaaa tcatgggcat ggaagtagaa gaaatctgcg
     7081 gccgcttcgg catcgggcgg gacaactgct acgtcatcct gcaccgggca cgcaacagcc
     7141 tgcgccgctg tctgcaactg cgctggttcg acatcggcgc gtaaggagga aaacatgttc
     7201 aaatgccgcg aagcctgcaa actgctgtcc gaagcgcaag acaggaaact gaccctgcgc
     7261 gaacgcgtcc tgcttaactt ccacctggcc gtctgcccgc tctgccgccg ctaccgcaaa
     7321 cagcttgcct ttctgcgcga aaacctgaaa aaatggctgt ccgacaaata ttcctaaatc
     7381 ccgtttatct gttttcagac ggcctctgca tcgaaaaggc cgtctgaaac aaacatccga
     7441 aagagaaaat catgcaaaca caagccgtta tcgaacacat cgtccgctgg ctgcacgact
     7501 atgccggcca ggcgcgcgtt aaaggcttta tcgtcggcat ttccggcggc atcgattccg
     7561 ccgtcgtttc cgcattggcc gcccgaacag gcctcgacgt gctgctgttg gaaatgccca
     7621 tccgccagca ggccgaacaa atcgaccgcg cgcagcagca cattgccgat ttgcaaagcc
     7681 gttttgccaa cgtccgcagc ctgcgcgtcg accttacccc cgccttcaac tgctttgccg
     7741 acacggtgga ggtcagcgag gccgagtatc cggccaagca gctcgcgctg gccaacagcc
     7801 gcgcccgcct gcgtatgctg accctgtatt actacggcca aatcaacggc cttctggtta
     7861 cggggacggg caacaaaatc gaagatttcg gcgtgggttt cttcaccaaa tacggtgacg
     7921 gcggcgtgga catcagcccg attgccgacc tcaccaaaac tcaggtttac cgtttggccg
     7981 aaagtctgaa tattatcgag gcgatacgga aagccgttcc taccgacggc ctgtgggaca
     8041 ccgagcgcac cgacgaacag caaatgggcg cgagttatcc cgaattggaa tgggcgatgg
     8101 acatcccagc cgacaagcag cccgaagatt tcgaagggcg gcagcgcgaa gtgctggcga
     8161 tttaccgccg tctgaaccgt gccgcgcagc acaaaatcca accgattccg gtctgcaacg
     8221 tgccgaagga gtggttggca tagggcatgg cggcagtgaa acggattgac ccgaaagacg
     8281 gtgccgttat ccgctataca tgctttgagg ccgtctgaaa aacagttttc agacggcctc
     8341 gatgtttgtc ggttttgttt gcttaaaaac cggacggttt ttattttttg gtttcacggt
     8401 cgcttcggcg gccgtcggct tcatatttgc cgccgcgtat gttcagccgc tccagcagtg
     8461 cgccgtctcc ggacggtatg ccgtccatgc accagacatc gtggagtacg gcgcgtacgg
     8521 cggcattgct ggtggctgcg ccgcccaatt cctgccattg cggattgcgt gccttgatcc
     8581 agcgtttgtt tacggggtcg ccgtaggcat aaattttata agagtgtttt ttgccttgtt
     8641 ggctggagaa cgagccgggc gcgcaataca gtgcctcgct gctgatgttg tcaatgcctt
     8701 ttcccgaacg gaggttgagg acgtagcgta cggtgccgtc ttcggccgca tggatgctgt
     8761 cgggggaaat caggaggtgt ttgtcgaagg tgggggaaac gtagagttcg aaccattttg
     8821 tgccttcggc agggaagggg ggcagggctt cttccgcttc ggtgaaggtg cggcgtttga
     8881 tgtcggcctc ggtttccaca tagcgtgagc tgttttcgtt ttctttcagg ctgaaccttt
     8941 ccgcttgggc aaagggggcg gtaagcagga gggcgaatag ggcggcgtat tttcttggca
     9001 tgtcatttcc ttgtgtggga ggttgtgcgg cggattctag caccaacggc gggtcggcag
     9061 acaagttttg ccgtaccgtg gggcggtatg ccgacgaaag gcgtataatc cgccgctttt
     9121 gatttgaggc gatgaaaatg agcgaacatt atctggatgt aaccgggctg aaatgcccgc
     9181 tgccgatttt gagggcgaaa aaggctttgg ccgctttggt ctgcggcgac gttttgacgg
     9241 tcgatgtcac ggatgcgggc gcgccggacg attttgccgc gttctgccgc caaaccggcc
     9301 atgtgctgct ggcttcggag gagcgggaag gtgtgttcag gctggttatc cggcataaat
     9361 aggctgcaat aggctgcggc ggataaaggt tcaggccgtc tgaaaaccgg gacaacggtg
     9421 tttcagacgg cctgaaccgt gtgcgcgttt agaaacgccg tttcagcccg caggcctgca
     9481 tgatgctggc ggcgagttct tccaccgatt tgtgcgtggt gttggtgaac gggatgtcga
     9541 agcggcggaa catggcctgc gcgtcggcca cttcctgttt gcaggtggag atgctggcgt
     9601 agttcgaatt cgggcggcgt tcttcacgga tgtcggccag tcgttcgggc ttgatggtga
     9661 ggccgtagat tttattgcgg tattgtttca ccatcggtgg caggtcgggt ttgtcgaggt
     9721 cgtcgggcgt gagcgggtag ttggcggcgc ggatgccgta ttgcagggcg agatacaggc
     9781 aggtcggggt ttttccgctg cgcgatacgc ccatcaggat tacgtcggca tctttcaggt
     9841 ctttgtcgct gacgccgtcg tcgtggttga gggtgaagtt taccgcttcc atgcgggcat
     9901 cgtagcgggc ggtgtcggcg atgccgtgat tgcgtccgac ttcgttgcgg gccttggtgc
     9961 ccagttcttt ttccaatatg ccgaggaagg catcgaaaaa actcaggtgc aggcccgggc
    10021 tgttgcggat gatgtcgcgg atttcttcgt tgatgatgct ggagaaaacc aaaggccgca
    10081 tggcggtctg attggcggcg gtttcaatga tttttaccat cgcacgggct ttgtccggcg
    10141 tatcgacgaa agggtaggtg gagcgtttga atttcacttc ctgaaattgg tcgagcaagg
    10201 cttcgcccat gctttcggaa gtcaggccgg tgcggtcgga aataaaaaag gcgtgtctgc
    10261 gcgacataat gatgtggctc tctttcgctg tctggtttgg aaaacaggtg cggatgatag
    10321 caagatgccg tctgaaattg aagtgcggga tggatgctac atggtgctac atgaaatttt
    10381 ggtcaaatat aatttagcta ttaaatttct ttttaatttt tttatcagca taaaatttct
    10441 ttgttgtgcg taaaatttgc ttgattaggg gtttgcaata tcatttaact ataagatttg
    10501 gtggtgttta catcggtttt acatttgtcg gtcggatttt gtttcactcg actacaatga
    10561 ggcggagcgc aattttcaga cggccgaaac acacgggccg tctgaaaaaa gcatgacacg
    10621 aaggcacagg ctggttacaa tgccgcgctg aatcctttac ctttcccaac ctttattttg
    10681 gacgacacaa atggctgaaa attatgttat ctggtttgaa aatctgcgta tgaccgatgt
    10741 ggagcgcgtt ggcggaaaaa acgcttccct cggcgagatg attagccaac tgacagaaaa
    10801 aggcgtgcgc gtgccgggcg gtttcgccac aacggcggaa gcctaccgcg cattcttggc
    10861 g
//
