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Overview
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1.5

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP031252.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | RiPP-like | 244,933 | 255,793 |
Region 2 | hserlactone | 600,492 | 621,241 |
Region 3 | terpene | 1,009,708 | 1,029,094 |
Region 4 | terpene | 1,901,589 | 1,922,404 |
Region 5 | arylpolyene | 2,101,729 | 2,146,546 | APE Vf | Other | 15%

NZ_CP031252.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 244,933 - 255,793 nt. (total: 10,861 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.16 | Other | nucleocidin | Streptomyces calvus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.47 | Other | nucleocidin | Streptomyces calvus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP031252.1 - Region 2 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 600,492 - 621,241 nt. (total: 20,750 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001682.1 |  | 0.34 | Other | N-acyl lysine/ornithine | Pseudomonas aeruginosa LESB58
BGC0001514.1 |  | 0.13 | Other | aristeromycin | Streptomyces citricolor
BGC0000469.1 |  | 0.06 | RiPP | bottromycin A2 | Streptomyces sp. BC16019
BGC0001302.1 |  | 0.05 | Other | lomofungin | Streptomyces lomondensis
BGC0001111.1 |  | 0.05 | NRP, Polyketide | rhizopodin | Stigmatella aurantiaca Sg a15
BGC0000935.1 |  | 0.04 | Other (Aminocoumarin), Polyketide | esmeraldin | Streptomyces antibioticus
BGC0001770.1 |  | 0.04 | Polyketide | sceliphrolactam | Streptomyces sp. SD85
BGC0001908.1 |  | 0.04 | Polyketide | sceliphrolactam | Streptomyces sp. SD85
BGC0000993.1 |  | 0.04 | NRP, Polyketide | FR901228 | Chromobacterium violaceum
BGC0000385.1 |  | 0.03 | NRP | lysobactin | Lysobacter sp. ATCC 53042

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001682.1 |  | 0.67 | Other | N-acyl lysine/ornithine | Pseudomonas aeruginosa LESB58
BGC0001514.1 |  | 0.42 | Other | aristeromycin | Streptomyces citricolor
BGC0000469.1 |  | 0.25 | RiPP | bottromycin A2 | Streptomyces sp. BC16019
BGC0001302.1 |  | 0.24 | Other | lomofungin | Streptomyces lomondensis
BGC0001111.1 |  | 0.23 | NRP, Polyketide | rhizopodin | Stigmatella aurantiaca Sg a15
BGC0000935.1 |  | 0.20 | Other (Aminocoumarin), Polyketide | esmeraldin | Streptomyces antibioticus
BGC0001770.1 |  | 0.19 | Polyketide | sceliphrolactam | Streptomyces sp. SD85
BGC0001908.1 |  | 0.19 | Polyketide | sceliphrolactam | Streptomyces sp. SD85
BGC0000993.1 |  | 0.17 | NRP, Polyketide | FR901228 | Chromobacterium violaceum
BGC0000385.1 |  | 0.16 | NRP | lysobactin | Lysobacter sp. ATCC 53042

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP031252.1 - Region 3 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,009,708 - 1,029,094 nt. (total: 19,387 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.33 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000656.1 |  | 0.19 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000892.1 |  | 0.18 | Other | caryoynencin | Burkholderia gladioli BSR3
BGC0000634.1 |  | 0.17 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000643.1 |  | 0.17 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000630.1 |  | 0.16 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000703.1 |  | 0.16 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000640.1 |  | 0.16 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000486.1 |  | 0.15 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0001222.1 |  | 0.15 | RiPP | acidocin B | Lactobacillus acidophilus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.66 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000656.1 |  | 0.50 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000892.1 |  | 0.50 | Other | caryoynencin | Burkholderia gladioli BSR3
BGC0000634.1 |  | 0.49 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000643.1 |  | 0.49 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000630.1 |  | 0.47 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000703.1 |  | 0.47 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000640.1 |  | 0.46 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000486.1 |  | 0.46 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0001222.1 |  | 0.45 | RiPP | acidocin B | Lactobacillus acidophilus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP031252.1 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,901,589 - 1,922,404 nt. (total: 20,816 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.20 | Terpene | carotenoid | Myxococcus xanthus
BGC0000923.1 |  | 0.14 | Other | paerucumarin | Pseudomonas aeruginosa PAO1
BGC0001903.1 |  | 0.07 | Other | neocarazostatin A | Streptomyces sp. MA37
BGC0000205.1 |  | 0.06 | Polyketide | bryostatin | Candidatus Endobugula sertula
BGC0001127.1 |  | 0.04 | NRP | jagaricin | Janthinobacterium agaricidamnosum
BGC0001215.1 |  | 0.03 | NRP | conglobatin | Streptomyces conglobatus
BGC0000344.1 |  | 0.03 | NRP | entolysin | Pseudomonas entomophila L48
BGC0002025.1 |  | 0.03 | NRP | thaxteramide C | Jahnella sp. MSr9139

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.52 | Terpene | carotenoid | Myxococcus xanthus
BGC0000923.1 |  | 0.43 | Other | paerucumarin | Pseudomonas aeruginosa PAO1
BGC0001903.1 |  | 0.28 | Other | neocarazostatin A | Streptomyces sp. MA37
BGC0000205.1 |  | 0.27 | Polyketide | bryostatin | Candidatus Endobugula sertula
BGC0001127.1 |  | 0.17 | NRP | jagaricin | Janthinobacterium agaricidamnosum
BGC0001215.1 |  | 0.16 | NRP | conglobatin | Streptomyces conglobatus
BGC0000344.1 |  | 0.16 | NRP | entolysin | Pseudomonas entomophila L48
BGC0002025.1 |  | 0.16 | NRP | thaxteramide C | Jahnella sp. MSr9139

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP031252.1 - Region 5 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,101,729 - 2,146,546 nt. (total: 44,818 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001897.1 |  | 0.20 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001831.1 |  | 0.19 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000234.1 |  | 0.19 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000774.1 |  | 0.19 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0002008.1 |  | 0.18 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.17 | Other | APE Ec | Escherichia coli CFT073
BGC0001723.1 |  | 0.17 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000218.1 |  | 0.17 | Polyketide | doxorubicin | Streptomyces peucetius
BGC0000217.1 |  | 0.17 | Polyketide | daunorubicin | Streptomyces sp.
BGC0001138.1 |  | 0.17 | Other (Nucleoside) | a201a | Marinactinospora thermotolerans

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001897.1 |  | 0.52 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001831.1 |  | 0.52 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000234.1 |  | 0.52 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000774.1 |  | 0.51 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0002008.1 |  | 0.49 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.48 | Other | APE Ec | Escherichia coli CFT073
BGC0001723.1 |  | 0.48 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000218.1 |  | 0.48 | Polyketide | doxorubicin | Streptomyces peucetius
BGC0000217.1 |  | 0.48 | Polyketide | daunorubicin | Streptomyces sp.
BGC0001138.1 |  | 0.48 | Other (Nucleoside) | a201a | Marinactinospora thermotolerans

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names