LOCUS       NC_008148.1            23125 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_008148.1 Rubrobacter xylanophilus DSM 9941, complete sequence.
ACCESSION   NC_008148
VERSION     NC_008148.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:24:27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1583289
            Orig. end    :: 1606414
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1047
                     /NRPS_PKS="Domain: PKS_ER (10-346). E-value: 4.1e-35.
                     Score: 113.2. Matches aSDomain:
                     nrpspksdomains_ctg1_1590_PKS_ER.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 244.3; E-value: 3e-74)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1590"
                     /transl_table=11
                     /translation="MKAVLLTGHGGLEKLEYREDIPTPSPAPGEVLIKVGAAGVNNTDI
                     WTREGAYGTEIDSEATSGWRRGKPMEFPRIQGMDIAGRIAEVGEGVPRSRIGERVLVDF
                     VLRSGEGDEGLVEADLVGSERDGGFAEYVAVPATNAVAVESPLSDEELATFPTAYLTAE
                     HMLNRASVAEDETIFVTGASGGVGSALLQLARLRGARVIALVGAGKENKAYELGAESVV
                     TRGTPDLPAAVAKAADGHPVDVVADVVGGEVFLDLLRILRPLGRYVTAGAIAGPLVRLD
                     LRTVYLKHLQLIGSTVGTRAEFIELVRYIESGKIKPLLANTYPLSEIRRAQEDFLRKDF
                     FGKLVIIP"
     protocluster    1..23125
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[1592302:1596568]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9014..13279
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..23125
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23125
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="5"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     aSDomain        31..1038
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1590_PKS_ER.1"
                     /evalue="4.10E-35"
                     /label="ctg1_1590_PKS_ER.1"
                     /locus_tag="ctg1_1590"
                     /protein_end="346"
                     /protein_start="10"
                     /score="113.2"
                     /tool="antismash"
                     /translation="GLEKLEYREDIPTPSPAPGEVLIKVGAAGVNNTDIWTREGAYGTE
                     IDSEATSGWRRGKPMEFPRIQGMDIAGRIAEVGEGVPRSRIGERVLVDFVLRSGEGDEG
                     LVEADLVGSERDGGFAEYVAVPATNAVAVESPLSDEELATFPTAYLTAEHMLNRASVAE
                     DETIFVTGASGGVGSALLQLARLRGARVIALVGAGKENKAYELGAESVVTRGTPDLPAA
                     VAKAADGHPVDVVADVVGGEVFLDLLRILRPLGRYVTAGAIAGPLVRLDLRTVYLKHLQ
                     LIGSTVGTRAEFIELVRYIESGKIKPLLANTYPLSEIRRAQEDFLRKDFFGKLVI"
     PFAM_domain     82..426
                     /aSDomain="ADH_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08240.14"
                     /description="Alcohol dehydrogenase GroES-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1590_0116"
                     /evalue="5.80E-15"
                     /label="ctg1_1590"
                     /locus_tag="ctg1_1590"
                     /protein_end="142"
                     /protein_start="27"
                     /score="55.2"
                     /tool="antismash"
                     /translation="PGEVLIKVGAAGVNNTDIWTREGAYGTEIDSEATSGWRRGKPMEF
                     PRIQGMDIAGRIAEVGEGVPRSRIGERVLVDFVLRSGEGDEGLVEADLVGSERDGGFAE
                     YVAVPATNAVA"
     CDS_motif       457..498
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1590_0001"
                     /evalue="2.40E-03"
                     /label="PKSI-ER_m4"
                     /locus_tag="ctg1_1590"
                     /protein_end="166"
                     /protein_start="152"
                     /score="11.5"
                     /tool="antismash"
                     /translation="ATFPTAYLTAEHML"
     CDS_motif       520..582
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1590_0002"
                     /evalue="4.20E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="ctg1_1590"
                     /protein_end="194"
                     /protein_start="173"
                     /score="16.2"
                     /tool="antismash"
                     /translation="DETIFVTGASGGVGSALLQLA"
     PFAM_domain     553..933
                     /aSDomain="ADH_zinc_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00107.28"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1590_0117"
                     /evalue="1.90E-23"
                     /label="ctg1_1590"
                     /locus_tag="ctg1_1590"
                     /protein_end="311"
                     /protein_start="184"
                     /score="83.0"
                     /tool="antismash"
                     /translation="GVGSALLQLARLRGARVIALVGAGKENKAYELGAESVVTRGTPDL
                     PAAVAKAADGHPVDVVADVVGGEVFLDLLRILRPLGRYVTAGAIAGPLVRLDLRTVYLK
                     HLQLIGSTVGTRAEFIELVRYIE"
     CDS             complement(1477..2688)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.1; E-value: 1.9e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1591"
                     /transl_table=11
                     /translation="VKGSGFLRGALPFFCVVLAGLNLRASITSVGPVIGGIREDMGLSS
                     GLAGLLTTLPLLAFAAFSSLAPRLAGRFGLSRTLFGGLVLLAAGIALRSLPQEAALFAG
                     TAVLGAAIAAANVLLPGFVKRYFPRRVGPVTGTYITAMNVGAALGAGLSAPLARSAGLG
                     WQGALGVWAVPVLLAVLAWAPLLKERPERSAPGRAPRGPWRSALAWQVTLFMGLQSVVF
                     FVSITWLPAILGEGGLSAVGAGWMVSLMQLVGIPATLLVPVLAARMRSQSALAAGAALL
                     SGTGILGLLFLGGPLSSVPVVLLGLGQGAAISLALTLFALRAADAAGAAALSGMAQTVG
                     YLFAAAGPPLFGALHDATGGWTVPLVVLCLVTGAMLLAGIGAGRDAVVRVPERRPADVR
                     RPRS"
     PFAM_domain     complement(1657..2640)
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1591_0118"
                     /evalue="1.80E-23"
                     /label="ctg1_1591"
                     /locus_tag="ctg1_1591"
                     /protein_end="344"
                     /protein_start="16"
                     /score="83.1"
                     /tool="antismash"
                     /translation="VLAGLNLRASITSVGPVIGGIREDMGLSSGLAGLLTTLPLLAFAA
                     FSSLAPRLAGRFGLSRTLFGGLVLLAAGIALRSLPQEAALFAGTAVLGAAIAAANVLLP
                     GFVKRYFPRRVGPVTGTYITAMNVGAALGAGLSAPLARSAGLGWQGALGVWAVPVLLAV
                     LAWAPLLKERPERSAPGRAPRGPWRSALAWQVTLFMGLQSVVFFVSITWLPAILGEGGL
                     SAVGAGWMVSLMQLVGIPATLLVPVLAARMRSQSALAAGAALLSGTGILGLLFLGGPLS
                     SVPVVLLGLGQGAAISLALTLFALRAADAAGAAALSGMAQTVGYLFA"
     CDS             complement(2708..3883)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 235.2; E-value:
                     2.7e-71)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1592"
                     /transl_table=11
                     /translation="MRTQVGIVGGGPAGLLLSHLLHLRGIESVVLERRSREELESEIRA
                     GVLEQGTMDLLNEIGVGERMMREGAFHRGVNLQFGGRRHRIDFEDLVGRGIMLYGQHEV
                     VKDLIAARLASGGKIVFEAQVLAVEGADTDSPSVRYAGPDGREEALSCDFVAGCDGFHG
                     ACRPSIPEGARREYERRYPFGWFGILVRAPRSSEELIYCLHERGFALISTRSPEIQRMY
                     LQCDPDDDVANWPDERVWEELHARLAMEDGWRLKEGPILQKGIVAMRSFVCEPMRYGRL
                     FLAGDAAHIVPPTGAKGMNLAVADVRVLCEALAEFYASGRAELLDAYSERCLRRVWKAQ
                     RFSWWMTSMLHRFHGEDEFRYRLQVAELDYVTGSRAASTSLAENYTGLPLE"
     aSDomain        complement(2714..3883)
                     /aSDomain="TIGR02360"
                     /aSTool="tigrfam"
                     /description="pbenz_hydroxyl: 4-hydroxybenzoate
                     3-monooxygenase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1592_0029"
                     /evalue="2.30E-163"
                     /identifier="TIGR02360"
                     /label="ctg1_1592"
                     /locus_tag="ctg1_1592"
                     /protein_end="390"
                     /protein_start="0"
                     /score="541.5"
                     /tool="antismash"
                     /translation="MRTQVGIVGGGPAGLLLSHLLHLRGIESVVLERRSREELESEIRA
                     GVLEQGTMDLLNEIGVGERMMREGAFHRGVNLQFGGRRHRIDFEDLVGRGIMLYGQHEV
                     VKDLIAARLASGGKIVFEAQVLAVEGADTDSPSVRYAGPDGREEALSCDFVAGCDGFHG
                     ACRPSIPEGARREYERRYPFGWFGILVRAPRSSEELIYCLHERGFALISTRSPEIQRMY
                     LQCDPDDDVANWPDERVWEELHARLAMEDGWRLKEGPILQKGIVAMRSFVCEPMRYGRL
                     FLAGDAAHIVPPTGAKGMNLAVADVRVLCEALAEFYASGRAELLDAYSERCLRRVWKAQ
                     RFSWWMTSMLHRFHGEDEFRYRLQVAELDYVTGSRAASTSLAENYTGLPL"
     PFAM_domain     complement(2858..3880)
                     /aSDomain="FAD_binding_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01494.21"
                     /description="FAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1592_0119"
                     /evalue="1.10E-84"
                     /label="ctg1_1592"
                     /locus_tag="ctg1_1592"
                     /protein_end="342"
                     /protein_start="1"
                     /score="284.7"
                     /tool="antismash"
                     /translation="RTQVGIVGGGPAGLLLSHLLHLRGIESVVLERRSREELESEIRAG
                     VLEQGTMDLLNEIGVGERMMREGAFHRGVNLQFGGRRHRIDFEDLVGRGIMLYGQHEVV
                     KDLIAARLASGGKIVFEAQVLAVEGADTDSPSVRYAGPDGREEALSCDFVAGCDGFHGA
                     CRPSIPEGARREYERRYPFGWFGILVRAPRSSEELIYCLHERGFALISTRSPEIQRMYL
                     QCDPDDDVANWPDERVWEELHARLAMEDGWRLKEGPILQKGIVAMRSFVCEPMRYGRLF
                     LAGDAAHIVPPTGAKGMNLAVADVRVLCEALAEFYASGRAELLDAYSERCLRRVWKAQR
                     F"
     CDS             complement(4060..5433)
                     /locus_tag="ctg1_1593"
                     /transl_table=11
                     /translation="MDRRSLEDVLSEAKSPVELLRNSQIGPYAFPGVPAEFTNWRDEQR
                     AWRESCVLFDQSYHMTDLYIEGPDVKRLLSDLGINSFEGFKKNNAKQFVACNHDGYVIG
                     DAILFGLEDDRVSLVGRPTAHNWVQYHAESGDYDVKVERDERYAANPEKRRRLYRYQIQ
                     GPNAAELLEKLNGGPLPQVPFFSMYEINIGDRKVRALRHGMSGQPGAEIFGPWEERDEI
                     KGIIVEAGEEYGLRQVGSRTYATNTLESGWIPSPCPAIYTGEEMKPYRQWLPANGYEAM
                     ASLGGSFYSERIEDYYFTPYELGYGRFVKFDHDFVGREALEEMADAPQRRKVTLVWEGE
                     DVAGVFGSLFEREGLPAKYIDLPLSNYATLPYDRVEKDGRVVGVSTYTGYSYNERAMLS
                     LAVVEEEFCEPGTEVVLLWGEEPNSSKPTVEEHRQVEIRARVQPAPLVEFARTAYRSS"
     PFAM_domain     complement(4630..5373)
                     /aSDomain="GCV_T"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01571.23"
                     /description="Aminomethyltransferase folate-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1593_0120"
                     /evalue="1.90E-60"
                     /label="ctg1_1593"
                     /locus_tag="ctg1_1593"
                     /protein_end="268"
                     /protein_start="20"
                     /score="204.4"
                     /tool="antismash"
                     /translation="RNSQIGPYAFPGVPAEFTNWRDEQRAWRESCVLFDQSYHMTDLYI
                     EGPDVKRLLSDLGINSFEGFKKNNAKQFVACNHDGYVIGDAILFGLEDDRVSLVGRPTA
                     HNWVQYHAESGDYDVKVERDERYAANPEKRRRLYRYQIQGPNAAELLEKLNGGPLPQVP
                     FFSMYEINIGDRKVRALRHGMSGQPGAEIFGPWEERDEIKGIIVEAGEEYGLRQVGSRT
                     YATNTLESGWIPSPCPAIYTGEEMKP"
     CDS             complement(5534..6496)
                     /locus_tag="ctg1_1594"
                     /transl_table=11
                     /translation="LGARVIDGRPIAGELKKRVASEVEGLAARGVRPGLATVLVGEDYA
                     ARAYERRVGGLAAELGCRYVCERLPREAEEADVLAVVGKLNADPRVSGILVLRPLPGHI
                     SEPAVFSALDPLKDIEAVHPVNAGLLALGRPRYVPSTPAACFYLLDRYLERSGRPPEEF
                     YPRSTVVVVGRSNNVGKPAVSLGFARGAAVISCDANAYRAGRLREHTLKADALIVAAGV
                     AGLIDESYVREGVIAVDVGINPVADPGGSGRTLLVGDLDFGSVARKAEALTPVPGGVGP
                     ITDVWLLKNTVAAGRGLAFRARSGGERGAPGISGGYGGQ"
     PFAM_domain     complement(5615..6130)
                     /aSDomain="THF_DHG_CYH_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02882.21"
                     /description="Tetrahydrofolate
                     dehydrogenase/cyclohydrolase, NAD(P)-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1594_0122"
                     /evalue="2.60E-39"
                     /label="ctg1_1594"
                     /locus_tag="ctg1_1594"
                     /protein_end="294"
                     /protein_start="122"
                     /score="134.2"
                     /tool="antismash"
                     /translation="HPVNAGLLALGRPRYVPSTPAACFYLLDRYLERSGRPPEEFYPRS
                     TVVVVGRSNNVGKPAVSLGFARGAAVISCDANAYRAGRLREHTLKADALIVAAGVAGLI
                     DESYVREGVIAVDVGINPVADPGGSGRTLLVGDLDFGSVARKAEALTPVPGGVGPITDV
                     WLLKNTVAA"
     PFAM_domain     complement(6137..6481)
                     /aSDomain="THF_DHG_CYH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00763.25"
                     /description="Tetrahydrofolate
                     dehydrogenase/cyclohydrolase, catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1594_0121"
                     /evalue="2.00E-26"
                     /label="ctg1_1594"
                     /locus_tag="ctg1_1594"
                     /protein_end="120"
                     /protein_start="5"
                     /score="92.6"
                     /tool="antismash"
                     /translation="IDGRPIAGELKKRVASEVEGLAARGVRPGLATVLVGEDYAARAYE
                     RRVGGLAAELGCRYVCERLPREAEEADVLAVVGKLNADPRVSGILVLRPLPGHISEPAV
                     FSALDPLKDIE"
     CDS             complement(6506..7087)
                     /locus_tag="ctg1_1595"
                     /transl_table=11
                     /translation="LSGRGGASGIPDYLQMPLGRFLEALSSGEPAPGGGAAAAVSVAMA
                     AGLAAMAARLSSAGELAERADALREEVAPLARADAEAFGRVLAAYRLPRGSEGRRERIG
                     EALGEAAGVPLEMARIGAEVCRLAGRLALEGNPNLKGDAVAGALLAEAGVRAAAELVEA
                     NEPEGERALEARRFVEAARRAREKMAQGGG"
     PFAM_domain     complement(6551..7036)
                     /aSDomain="FTCD_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04961.14"
                     /description="Formiminotransferase-cyclodeaminase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1595_0123"
                     /evalue="7.90E-39"
                     /label="ctg1_1595"
                     /locus_tag="ctg1_1595"
                     /protein_end="179"
                     /protein_start="17"
                     /score="133.4"
                     /tool="antismash"
                     /translation="LGRFLEALSSGEPAPGGGAAAAVSVAMAAGLAAMAARLSSAGELA
                     ERADALREEVAPLARADAEAFGRVLAAYRLPRGSEGRRERIGEALGEAAGVPLEMARIG
                     AEVCRLAGRLALEGNPNLKGDAVAGALLAEAGVRAAAELVEANEPEGERALEARRFVE"
     CDS             complement(7084..8814)
                     /locus_tag="ctg1_1596"
                     /transl_table=11
                     /translation="VGEALSNLEIARGAKLLPIEEVGRSMGLREERHLEPYGRHVAKVD
                     LCAIEDLSERPKAKYILVSAITPTPLGEGKTTTTVGLGQAFSHIGKRATIAIRQASMGP
                     AFGIKGGAAGGGYSQVVPMERLNLHLTGDLHAVTEAHNMLAAMIDNHLYHGNGLGIEPH
                     SISWRRVMDVNDRSLRNIVIGLGARTDGVPRQSGFDITAASEVMAILALASSLEDLRER
                     LGRIVIGHDREGNPVSAEDVRGAGAMAVILKEAIKPNLMQTLEGTPALVHAGPFGNIAT
                     GNSSVVADLIGIRTADYLITEAGFGADMGAERFFNIKCRISGLEPDAAVVVATVRALKA
                     HSGRYQIKAGAPLPEELLEENPQDVLAGAENLKKQIENIKLHGVPAVVAINAFPTDHPS
                     EHKAIEEAAKEVGARCAVCRHFTEGGKGAVELARALEETIEENERERRRGGGGSFRFLY
                     PLEMPLKQKIETIAREVYGAEGVEYDAEALRALEGFERAGFGRLPVCLAKTHLSLSSDP
                     ALKGAPRGWKLSVREVRASVGAGFIYPICGQMRTMPGLSAHPAAERIDLDGEGNVVGLF
                     "
     PFAM_domain     complement(7087..8799)
                     /aSDomain="FTHFS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01268.21"
                     /description="Formate--tetrahydrofolate ligase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1596_0124"
                     /evalue="1.40E-247"
                     /label="ctg1_1596"
                     /locus_tag="ctg1_1596"
                     /protein_end="576"
                     /protein_start="5"
                     /score="822.5"
                     /tool="antismash"
                     /translation="SNLEIARGAKLLPIEEVGRSMGLREERHLEPYGRHVAKVDLCAIE
                     DLSERPKAKYILVSAITPTPLGEGKTTTTVGLGQAFSHIGKRATIAIRQASMGPAFGIK
                     GGAAGGGYSQVVPMERLNLHLTGDLHAVTEAHNMLAAMIDNHLYHGNGLGIEPHSISWR
                     RVMDVNDRSLRNIVIGLGARTDGVPRQSGFDITAASEVMAILALASSLEDLRERLGRIV
                     IGHDREGNPVSAEDVRGAGAMAVILKEAIKPNLMQTLEGTPALVHAGPFGNIATGNSSV
                     VADLIGIRTADYLITEAGFGADMGAERFFNIKCRISGLEPDAAVVVATVRALKAHSGRY
                     QIKAGAPLPEELLEENPQDVLAGAENLKKQIENIKLHGVPAVVAINAFPTDHPSEHKAI
                     EEAAKEVGARCAVCRHFTEGGKGAVELARALEETIEENERERRRGGGGSFRFLYPLEMP
                     LKQKIETIAREVYGAEGVEYDAEALRALEGFERAGFGRLPVCLAKTHLSLSSDPALKGA
                     PRGWKLSVREVRASVGAGFIYPICGQMRTMPGLSAHPAAERIDLDGEGNVVGLF"
     CDS             complement(9014..11008)
                     /NRPS_PKS="Domain: AMP-binding (101-523). E-value: 1.5e-58.
                     Score: 190.1. Matches aSDomain:
                     nrpspksdomains_ctg1_1597_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     203.2; E-value: 9.4e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1597"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-66, bitscore:
                     221.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEVLWAPPPDVLEKTEIGRYVRWLRAERGLGFGGYEDLWRWSVE
                     DLEGFWSSIWDFFGVRSYTPPQRALASREMPGARWFPGARLNYAERILAPAGDDARTAI
                     IAHSQSRGPLELTFGELREQVARARAGLLRLGVGPGDRVVAYLPNVPETVVAFLATASL
                     GAVWATCAPEFGPRSVVDRFGQLDPKVLLAVAGYRYGDRFVDRRSEVAAIREALPNLEH
                     LVHVPYAGGANDALPGAIAWEELLSEAAPLACEPVAFDHPLYVLFSSGTTGKPKAIVHG
                     HGGILLEHLKNLGLTWDLRPGDRLMWFTTTAWMMWNALVSALLLRAAIVTMDGNPVYPD
                     LAFQWRLAERVGATMLGVAPAFLMACRKAGLAVGKSFDFSSLRQLGAAGSPLPPEGFDW
                     VYEQLGPDVLLNIGSGGTDVCTGIVQGSPLQPVYRGEISGPCLGVDAAAFDERGRPVVG
                     EFGELVIRSPMPSMPVGFWNDPGDRRYRAAYFERFPGVWCHGDWIRFAERGSCVISGRS
                     DATLNRGGVRLGTGEIYAVVESLQEVRDSLVVHLEDDEGGPGELLLFVVLAPGAALDDG
                     LRDRISSTIRRELSPRHVPDTIEAVPSVPRTLSQKKLEVPVKRILLGARPDEVASRDSL
                     LDPTSLDAYAAYAAGRREGAGEGGRPASR"
     aSDomain        complement(9071..10999)
                     /aSDomain="TIGR01217"
                     /aSTool="tigrfam"
                     /description="ac_ac_CoA_syn: acetoacetate-CoA ligase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1597_0030"
                     /evalue="7.40E-233"
                     /identifier="TIGR01217"
                     /label="ctg1_1597"
                     /locus_tag="ctg1_1597"
                     /protein_end="646"
                     /protein_start="3"
                     /score="772.3"
                     /tool="antismash"
                     /translation="VLWAPPPDVLEKTEIGRYVRWLRAERGLGFGGYEDLWRWSVEDLE
                     GFWSSIWDFFGVRSYTPPQRALASREMPGARWFPGARLNYAERILAPAGDDARTAIIAH
                     SQSRGPLELTFGELREQVARARAGLLRLGVGPGDRVVAYLPNVPETVVAFLATASLGAV
                     WATCAPEFGPRSVVDRFGQLDPKVLLAVAGYRYGDRFVDRRSEVAAIREALPNLEHLVH
                     VPYAGGANDALPGAIAWEELLSEAAPLACEPVAFDHPLYVLFSSGTTGKPKAIVHGHGG
                     ILLEHLKNLGLTWDLRPGDRLMWFTTTAWMMWNALVSALLLRAAIVTMDGNPVYPDLAF
                     QWRLAERVGATMLGVAPAFLMACRKAGLAVGKSFDFSSLRQLGAAGSPLPPEGFDWVYE
                     QLGPDVLLNIGSGGTDVCTGIVQGSPLQPVYRGEISGPCLGVDAAAFDERGRPVVGEFG
                     ELVIRSPMPSMPVGFWNDPGDRRYRAAYFERFPGVWCHGDWIRFAERGSCVISGRSDAT
                     LNRGGVRLGTGEIYAVVESLQEVRDSLVVHLEDDEGGPGELLLFVVLAPGAALDDGLRD
                     RISSTIRRELSPRHVPDTIEAVPSVPRTLSQKKLEVPVKRILLGARPDEVASRDSLLDP
                     TSLDAYAA"
     aSDomain        complement(9440..10705)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1597_AMP-binding.1"
                     /evalue="1.50E-58"
                     /label="ctg1_1597_AMP-binding.1"
                     /locus_tag="ctg1_1597"
                     /protein_end="523"
                     /protein_start="101"
                     /score="190.1"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="TAIIAHSQSRGPLELTFGELREQVARARAGLLRLGVGPGDRVVAY
                     LPNVPETVVAFLATASLGAVWATCAPEFGPRSVVDRFGQLDPKVLLAVAGYRYGDRFVD
                     RRSEVAAIREALPNLEHLVHVPYAGGANDALPGAIAWEELLSEAAPLACEPVAFDHPLY
                     VLFSSGTTGKPKAIVHGHGGILLEHLKNLGLTWDLRPGDRLMWFTTTAWMMWNALVSAL
                     LLRAAIVTMDGNPVYPDLAFQWRLAERVGATMLGVAPAFLMACRKAGLAVGKSFDFSSL
                     RQLGAAGSPLPPEGFDWVYEQLGPDVLLNIGSGGTDVCTGIVQGSPLQPVYRGEISGPC
                     LGVDAAAFDERGRPVVGEFGELVIRSPMPSMPVGFWNDPGDRRYRAAYFERFPGVWCHG
                     DWIRFAERGSCVISGRSDATLNR"
     PFAM_domain     complement(9443..10708)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1597_0126"
                     /evalue="1.60E-54"
                     /label="ctg1_1597"
                     /locus_tag="ctg1_1597"
                     /protein_end="522"
                     /protein_start="100"
                     /score="185.3"
                     /tool="antismash"
                     /translation="RTAIIAHSQSRGPLELTFGELREQVARARAGLLRLGVGPGDRVVA
                     YLPNVPETVVAFLATASLGAVWATCAPEFGPRSVVDRFGQLDPKVLLAVAGYRYGDRFV
                     DRRSEVAAIREALPNLEHLVHVPYAGGANDALPGAIAWEELLSEAAPLACEPVAFDHPL
                     YVLFSSGTTGKPKAIVHGHGGILLEHLKNLGLTWDLRPGDRLMWFTTTAWMMWNALVSA
                     LLLRAAIVTMDGNPVYPDLAFQWRLAERVGATMLGVAPAFLMACRKAGLAVGKSFDFSS
                     LRQLGAAGSPLPPEGFDWVYEQLGPDVLLNIGSGGTDVCTGIVQGSPLQPVYRGEISGP
                     CLGVDAAAFDERGRPVVGEFGELVIRSPMPSMPVGFWNDPGDRRYRAAYFERFPGVWCH
                     GDWIRFAERGSCVISGRSDATLN"
     CDS_motif       complement(10163..10219)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1597_0001"
                     /evalue="2.10E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_1597"
                     /protein_end="282"
                     /protein_start="263"
                     /score="20.3"
                     /tool="antismash"
                     /translation="YVLFSSGTTGKPKAIVHGH"
     PFAM_domain     complement(10739..10903)
                     /aSDomain="ACAS_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16177.7"
                     /description="Acetyl-coenzyme A synthetase N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1597_0125"
                     /evalue="2.40E-13"
                     /label="ctg1_1597"
                     /locus_tag="ctg1_1597"
                     /protein_end="90"
                     /protein_start="35"
                     /score="49.8"
                     /tool="antismash"
                     /translation="YEDLWRWSVEDLEGFWSSIWDFFGVRSYTPPQRALASREMPGARW
                     FPGARLNYAE"
     CDS             complement(11008..11823)
                     /locus_tag="ctg1_1598"
                     /transl_table=11
                     /translation="LSGAMDLRDIRGFVFDVDGSLVHRDATFRARPLPGAPEVLKSIRA
                     SGRPLVLFTNGTHLRPEEFAEGLREGGLPVRDDEVLTPVCSALGYLSRRRKSGRVMVFG
                     SGTVRERLLEAGVRLTDGEDAEVVFVTHVNEVDFEALERAARAITRGARLLTANYGPGY
                     WGSDGMIFSRGAMLTAALAKATGARPVIVGKPSRPAVRAICDRLGLDSTEIAVIGDDLD
                     MDIALGRMGGSRTILVRSGISGARELDGVPERRRPDAVVNVVGEILEWL"
     PFAM_domain     complement(11026..11250)
                     /aSDomain="Hydrolase_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13242.8"
                     /description="HAD-hyrolase-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1598_0128"
                     /evalue="6.10E-15"
                     /label="ctg1_1598"
                     /locus_tag="ctg1_1598"
                     /protein_end="266"
                     /protein_start="191"
                     /score="55.2"
                     /tool="antismash"
                     /translation="VGKPSRPAVRAICDRLGLDSTEIAVIGDDLDMDIALGRMGGSRTI
                     LVRSGISGARELDGVPERRRPDAVVNVVGE"
     aSDomain        complement(11101..11787)
                     /aSDomain="TIGR01460"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IIA: HAD hydrolase, family IIA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1598_0031"
                     /evalue="6.30E-31"
                     /identifier="TIGR01460"
                     /label="ctg1_1598"
                     /locus_tag="ctg1_1598"
                     /protein_end="241"
                     /protein_start="12"
                     /score="106.0"
                     /tool="antismash"
                     /translation="FVFDVDGSLVHRDATFRARPLPGAPEVLKSIRASGRPLVLFTNGT
                     HLRPEEFAEGLREGGLPVRDDEVLTPVCSALGYLSRRRKSGRVMVFGSGTVRERLLEAG
                     VRLTDGEDAEVVFVTHVNEVDFEALERAARAITRGARLLTANYGPGYWGSDGMIFSRGA
                     MLTAALAKATGARPVIVGKPSRPAVRAICDRLGLDSTEIAVIGDDLDMDIALGRMGGSR
                     TILVRSG"
     PFAM_domain     complement(11473..11787)
                     /aSDomain="Hydrolase_6"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13344.8"
                     /description="Haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1598_0127"
                     /evalue="5.10E-22"
                     /label="ctg1_1598"
                     /locus_tag="ctg1_1598"
                     /protein_end="117"
                     /protein_start="12"
                     /score="77.9"
                     /tool="antismash"
                     /translation="FVFDVDGSLVHRDATFRARPLPGAPEVLKSIRASGRPLVLFTNGT
                     HLRPEEFAEGLREGGLPVRDDEVLTPVCSALGYLSRRRKSGRVMVFGSGTVRERLLEAG
                     V"
     CDS             complement(11801..13279)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 64.5; E-value:
                     1.5e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1599"
                     /sec_met_domain="HMGL-like (E-value: 1.1e-26, bitscore:
                     91.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGSVDIVDTTLRDGNQSLWSATGLTTQDVLAIAPTMDRVGFHAL
                     DFTSSTHMGISVRFHREDPWERIRLVSAAMPNTPLGLITTGMRFIRWVPAGEDLMRLAF
                     RCWVRNGMRRIQIVDPSNDPGALLRMARIAREEGFEEVVVGLTYSISPVHTHEYYLERA
                     AAAARSEDIDRLYLKDPGGLLTPDAVRALIPGFIERFAPRPVELHSHCTIGLGPLAYVE
                     GLRSGVRILHTAVEPLGSGSSNPPAGATLRNIEAEGLSCDLDTEALGVVSDYFHELARE
                     RGLPPGTPREFDGAYFRHQMPGGMISTTRRQLQELGRPELFDAVLEEVPRVRAEMGYPI
                     MVTPVSQFVATQAVMNVISGERWSKVSDEMVRYFLGHYYDPPAPVDADVADRVLSMPRA
                     DELKHLKPITLEGARERFGRRLSDEELLLRLTMPAEQVDAMVAERGRQRAPLVRPGRAP
                     LVRLLHELSKRKSISYLKLEDERTGDTIVWRHGS"
     PFAM_domain     complement(11963..12388)
                     /aSDomain="PYC_OADA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02436.20"
                     /description="Conserved carboxylase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1599_0130"
                     /evalue="5.30E-30"
                     /label="ctg1_1599"
                     /locus_tag="ctg1_1599"
                     /protein_end="439"
                     /protein_start="297"
                     /score="104.7"
                     /tool="antismash"
                     /translation="RHQMPGGMISTTRRQLQELGRPELFDAVLEEVPRVRAEMGYPIMV
                     TPVSQFVATQAVMNVISGERWSKVSDEMVRYFLGHYYDPPAPVDADVADRVLSMPRADE
                     LKHLKPITLEGARERFGRRLSDEELLLRLTMPAEQVDA"
     PFAM_domain     complement(12461..13267)
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1599_0129"
                     /evalue="1.10E-25"
                     /label="ctg1_1599"
                     /locus_tag="ctg1_1599"
                     /protein_end="273"
                     /protein_start="4"
                     /score="90.8"
                     /tool="antismash"
                     /translation="VDIVDTTLRDGNQSLWSATGLTTQDVLAIAPTMDRVGFHALDFTS
                     STHMGISVRFHREDPWERIRLVSAAMPNTPLGLITTGMRFIRWVPAGEDLMRLAFRCWV
                     RNGMRRIQIVDPSNDPGALLRMARIAREEGFEEVVVGLTYSISPVHTHEYYLERAAAAA
                     RSEDIDRLYLKDPGGLLTPDAVRALIPGFIERFAPRPVELHSHCTIGLGPLAYVEGLRS
                     GVRILHTAVEPLGSGSSNPPAGATLRNIEAEGLSCDLDTEALGVVSD"
     CDS             complement(13276..14622)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     632.6; E-value: 1.5e-191)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1600"
                     /sec_met_domain="ATP-grasp (E-value: 2.5e-05, bitscore:
                     21.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIKRVFVANRGEIAVRIIRACRRLGLEVVVGASEVDRGGLAARM
                     ADRAVCIGPGAPARSYLNVGAVVQAALGTGCDAIHPGYGFLSENPALASAAREHGLRFI
                     GPPAGVIELAGDKLRSRETAAAAGLPVVPGGEVRALEDALRFAEAHGYPVLLKAAAGGG
                     GRGIKLAWDRGQLERLFGVALAEAGAAFGDDRLYVERFIRRARHVEVQVAADEHGGVVH
                     FGERDCSVQRRYQKIVEEAPAPALDPGTRAALHAAAVRFAAEIGYRNLGTVEFVVDARS
                     GEFFFLEMNCRIQVEHPVTEAITGRDLVADQIRIAAGEPLEVTQEEVGFEGHAIECRLT
                     AEDAAHGFRPTPGRITRFSVPNLPGLRVDTHCEEGTLVPPYYDSLIAKLITFANDRSEA
                     AERMREALAGLRVEGVPTNRDLLSHIIAHPDFAGAAVSTGWLEEAVLAA"
     PFAM_domain     complement(13294..13617)
                     /aSDomain="Biotin_carb_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02785.21"
                     /description="Biotin carboxylase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1600_0133"
                     /evalue="2.30E-38"
                     /label="ctg1_1600"
                     /locus_tag="ctg1_1600"
                     /protein_end="443"
                     /protein_start="335"
                     /score="130.7"
                     /tool="antismash"
                     /translation="ECRLTAEDAAHGFRPTPGRITRFSVPNLPGLRVDTHCEEGTLVPP
                     YYDSLIAKLITFANDRSEAAERMREALAGLRVEGVPTNRDLLSHIIAHPDFAGAAVSTG
                     WLEE"
     PFAM_domain     complement(13657..14277)
                     /aSDomain="CPSase_L_D2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02786.19"
                     /description="Carbamoyl-phosphate synthase L chain, ATP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1600_0132"
                     /evalue="2.50E-72"
                     /label="ctg1_1600"
                     /locus_tag="ctg1_1600"
                     /protein_end="322"
                     /protein_start="115"
                     /score="242.9"
                     /tool="antismash"
                     /translation="DKLRSRETAAAAGLPVVPGGEVRALEDALRFAEAHGYPVLLKAAA
                     GGGGRGIKLAWDRGQLERLFGVALAEAGAAFGDDRLYVERFIRRARHVEVQVAADEHGG
                     VVHFGERDCSVQRRYQKIVEEAPAPALDPGTRAALHAAAVRFAAEIGYRNLGTVEFVVD
                     ARSGEFFFLEMNCRIQVEHPVTEAITGRDLVADQIRIAAGEPLE"
     PFAM_domain     complement(14290..14616)
                     /aSDomain="Biotin_carb_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00289.24"
                     /description="Biotin carboxylase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1600_0131"
                     /evalue="8.80E-39"
                     /label="ctg1_1600"
                     /locus_tag="ctg1_1600"
                     /protein_end="111"
                     /protein_start="2"
                     /score="132.6"
                     /tool="antismash"
                     /translation="IKRVFVANRGEIAVRIIRACRRLGLEVVVGASEVDRGGLAARMAD
                     RAVCIGPGAPARSYLNVGAVVQAALGTGCDAIHPGYGFLSENPALASAAREHGLRFIGP
                     PAGVI"
     CDS             complement(14622..15107)
                     /locus_tag="ctg1_1601"
                     /transl_table=11
                     /translation="MPLSDDDVREILRIIDESDLEELRIETNGLRLYVRRGGAPPVEEA
                     SGEEEKARPASEEKTHASAEPAAAGGRGAEAAPTPDGTVAIEAPMVGTFFRAEAPGAKP
                     FVEVGSRVEPDTVVCLIEVMKMMNSIRAGVSGRIVEVCAENGALVEYGQPLFRVEPE"
     aSDomain        complement(14631..15089)
                     /aSDomain="TIGR00531"
                     /aSTool="tigrfam"
                     /description="BCCP: acetyl-CoA carboxylase, biotin carboxyl
                     carrier protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1601_0032"
                     /evalue="8.10E-39"
                     /identifier="TIGR00531"
                     /label="ctg1_1601"
                     /locus_tag="ctg1_1601"
                     /protein_end="159"
                     /protein_start="6"
                     /score="131.6"
                     /tool="antismash"
                     /translation="DVREILRIIDESDLEELRIETNGLRLYVRRGGAPPVEEASGEEEK
                     ARPASEEKTHASAEPAAAGGRGAEAAPTPDGTVAIEAPMVGTFFRAEAPGAKPFVEVGS
                     RVEPDTVVCLIEVMKMMNSIRAGVSGRIVEVCAENGALVEYGQPLFRVE"
     PFAM_domain     complement(14637..14852)
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00364.24"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1601_0134"
                     /evalue="1.80E-19"
                     /label="ctg1_1601"
                     /locus_tag="ctg1_1601"
                     /protein_end="157"
                     /protein_start="85"
                     /score="69.5"
                     /tool="antismash"
                     /translation="IEAPMVGTFFRAEAPGAKPFVEVGSRVEPDTVVCLIEVMKMMNSI
                     RAGVSGRIVEVCAENGALVEYGQPLFR"
     CDS             complement(15108..16208)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1602"
                     /sec_met_domain="PPDK_N (E-value: 1.2e-100, bitscore:
                     334.6, seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSSAATGYTTPLDRLRRAEEPRFGGKSANLGELLSSEIPVPPGF
                     AISTDAFALFLEENGIRERVVRSLRALDPDDMSALRRVSEELVAAVLSAPLPGEVVGEV
                     ERRYRKIAELSGEESPPVAVRSSAVGEDSEQATFAGQQKTHLWVRGVDDVCAAVRSCWA
                     SLYSPEALSYRARMSAGGGEPAMGVAVQMMVDAEVAGVMFTCNPLNGDPSTVAVNASWG
                     LGEAVVAGEVTPDEYRVSKVTGEVLRRSVGCKHLEYRPDPGSAGVRAVEVEQARREVPC
                     LDEACLRALVEVARRVERHFGAPQDIEWAISRGRELPESLYVLQSRPVTTAPRRPEAGK
                     DLPRARSAIELVMGTFGVVRDDEGRS"
     PFAM_domain     complement(15198..16142)
                     /aSDomain="PPDK_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01326.21"
                     /description="Pyruvate phosphate dikinase, AMP/ATP-binding
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1602_0135"
                     /evalue="4.40E-100"
                     /label="ctg1_1602"
                     /locus_tag="ctg1_1602"
                     /protein_end="337"
                     /protein_start="22"
                     /score="335.2"
                     /tool="antismash"
                     /translation="RFGGKSANLGELLSSEIPVPPGFAISTDAFALFLEENGIRERVVR
                     SLRALDPDDMSALRRVSEELVAAVLSAPLPGEVVGEVERRYRKIAELSGEESPPVAVRS
                     SAVGEDSEQATFAGQQKTHLWVRGVDDVCAAVRSCWASLYSPEALSYRARMSAGGGEPA
                     MGVAVQMMVDAEVAGVMFTCNPLNGDPSTVAVNASWGLGEAVVAGEVTPDEYRVSKVTG
                     EVLRRSVGCKHLEYRPDPGSAGVRAVEVEQARREVPCLDEACLRALVEVARRVERHFGA
                     PQDIEWAISRGRELPESLYVLQSRPVTTAPRRPE"
     CDS             complement(16201..18033)
                     /locus_tag="ctg1_1603"
                     /transl_table=11
                     /translation="MVTEPERLEGFPSPFSIRTPEGCEGWEEMYPPWALFDERRREHDE
                     NRLWFWNSMHFPVPMPAFDMVEVDTPYYALGGWQNRAFAVPGAMGVDYRVVNGYVYISP
                     NPVTDPEKIAERSRFFQQRAGYYYENWDELYARWRERMEALNREVAEIPVPELPEYEPE
                     RVVFEGGEPSWATLLASYRRALDCVERMWQYHFEFLLLGYGAYLTFSEFCKQALPDIPD
                     QHISQMVAGIDVVLFRPDAELRRLARLAIELGVAGAFREGRSPEEIEAELARSDAGRRW
                     LKELGKVKDPWFNMGTGDGLYHYYGSWHDDPSIPYSSLVGHIAALQAGEDIERPTRELA
                     ERRDQLVREYEALLDEDARRTFRELLGLSRKVFPYVEEHKFYCDYWFQSRFFNKIREFG
                     ALLARHGFLEESEDIFQLSRYEAMQALEELALTWSTGGEALGPRHWPQIVARRKQLLKR
                     LEGWTPPPALGRMPEAVVDPAITMLWGVTPQQLQEWARAQRDGGGNELSGAAASPGEVE
                     GVARVVRSLDEISEVRGGEILVCTSTSPAWAPIFSKIKATVTDIGGIMSHAAIVSREYG
                     LPAVVGTGTATARIRTGQRLRVDGTSGRVVILDG"
     PFAM_domain     complement(16225..16437)
                     /aSDomain="PEP-utilizers"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00391.25"
                     /description="PEP-utilising enzyme, mobile domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1603_0136"
                     /evalue="6.30E-22"
                     /label="ctg1_1603"
                     /locus_tag="ctg1_1603"
                     /protein_end="603"
                     /protein_start="532"
                     /score="77.2"
                     /tool="antismash"
                     /translation="RGGEILVCTSTSPAWAPIFSKIKATVTDIGGIMSHAAIVSREYGL
                     PAVVGTGTATARIRTGQRLRVDGTSG"
     CDS             complement(18173..19114)
                     /locus_tag="ctg1_1604"
                     /transl_table=11
                     /translation="LDRVVADLLQHIRYEVIPLAGTEEAVERWLISRRAEEQKKTTITI
                     TASPTRGIEPTIALTERLGAKARRRGGEPSSLCVVPHLSARLIEDEHHLEEIVARLKEA
                     GVEEVFVIGGDAKEPRGRFHDALGLLEALEELGRPFERVGIAGYPEGHPSIERAELERA
                     LRKKALYASYVVSQLCFEAKKVLLWARRVRELGVGLPVVVGVAAPIDPKRLAGVAAKIG
                     IGDSARFLRKQRAKSLLRLLSPGRRRSALSLVYEPGGFLEELVEEGSREGFFASSGGTD
                     EGGGMISGLHLYTFNDLQRTLEWVREEKRSRG"
     PFAM_domain     complement(18500..18889)
                     /aSDomain="MTHFR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02219.19"
                     /description="Methylenetetrahydrofolate reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1604_0137"
                     /evalue="1.70E-11"
                     /label="ctg1_1604"
                     /locus_tag="ctg1_1604"
                     /protein_end="205"
                     /protein_start="75"
                     /score="44.1"
                     /tool="antismash"
                     /translation="SLCVVPHLSARLIEDEHHLEEIVARLKEAGVEEVFVIGGDAKEPR
                     GRFHDALGLLEALEELGRPFERVGIAGYPEGHPSIERAELERALRKKALYASYVVSQLC
                     FEAKKVLLWARRVRELGVGLPVVVGV"
     CDS             complement(19293..19679)
                     /locus_tag="ctg1_1605"
                     /transl_table=11
                     /translation="VSDPAYERGLRVRREVLGDAHVDRALASATDFTADFQDFITRYAW
                     GEVWTRPGLDRKTRSCMTMTALIAAGRLDELEMHVRAALRIGLTPDEIKEVILHSAIYC
                     GVPAANSAFAVAQRAISGQEDPGG"
     aSDomain        complement(19317..19667)
                     /aSDomain="TIGR02425"
                     /aSTool="tigrfam"
                     /description="decarb_PcaC: 4-carboxymuconolactone
                     decarboxylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1605_0033"
                     /evalue="1.60E-52"
                     /identifier="TIGR02425"
                     /label="ctg1_1605"
                     /locus_tag="ctg1_1605"
                     /protein_end="121"
                     /protein_start="4"
                     /score="174.8"
                     /tool="antismash"
                     /translation="AYERGLRVRREVLGDAHVDRALASATDFTADFQDFITRYAWGEVW
                     TRPGLDRKTRSCMTMTALIAAGRLDELEMHVRAALRIGLTPDEIKEVILHSAIYCGVPA
                     ANSAFAVAQRAIS"
     PFAM_domain     complement(19329..19577)
                     /aSDomain="CMD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02627.22"
                     /description="Carboxymuconolactone decarboxylase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1605_0138"
                     /evalue="1.00E-25"
                     /label="ctg1_1605"
                     /locus_tag="ctg1_1605"
                     /protein_end="117"
                     /protein_start="34"
                     /score="89.7"
                     /tool="antismash"
                     /translation="DFQDFITRYAWGEVWTRPGLDRKTRSCMTMTALIAAGRLDELEMH
                     VRAALRIGLTPDEIKEVILHSAIYCGVPAANSAFAVAQ"
     CDS             complement(19676..20461)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 152.3;
                     E-value: 3.7e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1606"
                     /sec_met_domain="Abhydrolase_6 (E-value: 8.3e-18, bitscore:
                     63.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 3.9e-29, bitscore: 99.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVELHHVVEGPADAPVLVLSSSLGTTHRMWDPQVPALRERFRLV
                     RYDHRGHGSSPVPPGPYSIAELGQDVLAMLDGLGVERFSFCGLSLGGMVGMWVASEVPE
                     RVERLVLCCTSALLGPRELWDERARVARSEGMEALVEGVVERWFTPALHQERPEDVERA
                     KRMLAATPPEGYAGCCEAIREMDLRDRLGRIQAPTLVISGSDDPATPPEHGERLREAIP
                     EARTVVIERAAHLANIERPEPFARALLEHLSPVLEGRSS"
     aSDomain        complement(19706..20449)
                     /aSDomain="TIGR02427"
                     /aSTool="tigrfam"
                     /description="protocat_pcaD: 3-oxoadipate enol-lactonase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1606_0034"
                     /evalue="1.40E-100"
                     /identifier="TIGR02427"
                     /label="ctg1_1606"
                     /locus_tag="ctg1_1606"
                     /protein_end="252"
                     /protein_start="4"
                     /score="333.8"
                     /tool="antismash"
                     /translation="LHHVVEGPADAPVLVLSSSLGTTHRMWDPQVPALRERFRLVRYDH
                     RGHGSSPVPPGPYSIAELGQDVLAMLDGLGVERFSFCGLSLGGMVGMWVASEVPERVER
                     LVLCCTSALLGPRELWDERARVARSEGMEALVEGVVERWFTPALHQERPEDVERAKRML
                     AATPPEGYAGCCEAIREMDLRDRLGRIQAPTLVISGSDDPATPPEHGERLREAIPEART
                     VVIERAAHLANIERPEPFARALLEHL"
     PFAM_domain     complement(19739..20416)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00561.22"
                     /description="alpha/beta hydrolase fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1606_0139"
                     /evalue="2.70E-28"
                     /label="ctg1_1606"
                     /locus_tag="ctg1_1606"
                     /protein_end="241"
                     /protein_start="15"
                     /score="99.4"
                     /tool="antismash"
                     /translation="PVLVLSSSLGTTHRMWDPQVPALRERFRLVRYDHRGHGSSPVPPG
                     PYSIAELGQDVLAMLDGLGVERFSFCGLSLGGMVGMWVASEVPERVERLVLCCTSALLG
                     PRELWDERARVARSEGMEALVEGVVERWFTPALHQERPEDVERAKRMLAATPPEGYAGC
                     CEAIREMDLRDRLGRIQAPTLVISGSDDPATPPEHGERLREAIPEARTVVIERAAHLAN
                     IERP"
     CDS             complement(20458..21804)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 157.8; E-value: 7.7e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1607"
                     /transl_table=11
                     /translation="MSGELFGPIFVPERFREAVSGGAWLRAMLEAEGALARAGARAGVV
                     PPEAAEEISRRCRELELDPEELGERGRAAGNPVPALVKELTAAVPGEAARHVHRGATSQ
                     DITDTAAMLISREALGLILRELDGVCAACARLAEEHRETLVAGRTLLQQALPTTFGLKA
                     AGWLVAALEARRVLREARERGLAAQLGGAAGTLASLGERGTRVLREYARLLALPEPALP
                     WHAARFRVAELGGALALAAGTLHKVALDVILMAQTEVGEAAEPSGGGRGGSSTLPHKRN
                     PILSVVASANARRVQDLARTLYGSLAQEHERAAGAWHAEWEALSGALALTGGAAAAVRE
                     ALEGLEVRPGRMAENLAVTEGLILAENVTTLAAERLGRLEAHELVEAACRRVAEGGGTL
                     REEILAEPRLREALSEEEIEGALDPARYLGAADEFVDRALEMYRREGQR"
     PFAM_domain     complement(20491..20724)
                     /aSDomain="ADSL_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10397.11"
                     /description="Adenylosuccinate lyase C-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1607_0141"
                     /evalue="6.20E-20"
                     /label="ctg1_1607"
                     /locus_tag="ctg1_1607"
                     /protein_end="438"
                     /protein_start="360"
                     /score="71.8"
                     /tool="antismash"
                     /translation="GLILAENVTTLAAERLGRLEAHELVEAACRRVAEGGGTLREEILA
                     EPRLREALSEEEIEGALDPARYLGAADEFVDRA"
     aSDomain        complement(20770..21777)
                     /aSDomain="TIGR02426"
                     /aSTool="tigrfam"
                     /description="protocat_pcaB: 3-carboxy-cis,cis-muconate
                     cycloisomerase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1607_0035"
                     /evalue="2.90E-113"
                     /identifier="TIGR02426"
                     /label="ctg1_1607"
                     /locus_tag="ctg1_1607"
                     /protein_end="345"
                     /protein_start="9"
                     /score="376.2"
                     /tool="antismash"
                     /translation="FVPERFREAVSGGAWLRAMLEAEGALARAGARAGVVPPEAAEEIS
                     RRCRELELDPEELGERGRAAGNPVPALVKELTAAVPGEAARHVHRGATSQDITDTAAML
                     ISREALGLILRELDGVCAACARLAEEHRETLVAGRTLLQQALPTTFGLKAAGWLVAALE
                     ARRVLREARERGLAAQLGGAAGTLASLGERGTRVLREYARLLALPEPALPWHAARFRVA
                     ELGGALALAAGTLHKVALDVILMAQTEVGEAAEPSGGGRGGSSTLPHKRNPILSVVASA
                     NARRVQDLARTLYGSLAQEHERAAGAWHAEWEALSGALALTGGAAAAVREALEGL"
     PFAM_domain     complement(20920..21723)
                     /aSDomain="Lyase_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00206.22"
                     /description="Lyase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1607_0140"
                     /evalue="2.10E-39"
                     /label="ctg1_1607"
                     /locus_tag="ctg1_1607"
                     /protein_end="295"
                     /protein_start="27"
                     /score="135.9"
                     /tool="antismash"
                     /translation="MLEAEGALARAGARAGVVPPEAAEEISRRCRELELDPEELGERGR
                     AAGNPVPALVKELTAAVPGEAARHVHRGATSQDITDTAAMLISREALGLILRELDGVCA
                     ACARLAEEHRETLVAGRTLLQQALPTTFGLKAAGWLVAALEARRVLREARERGLAAQLG
                     GAAGTLASLGERGTRVLREYARLLALPEPALPWHAARFRVAELGGALALAAGTLHKVAL
                     DVILMAQTEVGEAAEPSGGGRGGSSTLPHKRNPILSVVASANARRV"
     CDS             complement(21801..22391)
                     /locus_tag="ctg1_1608"
                     /transl_table=11
                     /translation="MGRQREELRLTPSQTVGPYLSLGLLREDWTHLVPPDHPRAIRIEG
                     TLYDGAGEPVTDGLVEIWQAAPSGRYDHPADDREELPLEEGFHGFGRSGTEDGGRFSFV
                     TLKPGPVPGPDGATQAPHIMVAVFARGLLKQLITRIYFEDEPEANAEDPVLRSIGDERL
                     RKTLIAGREGESRYRFDIRLQGEGQTAFFKLSP"
     aSDomain        complement(21813..22361)
                     /aSDomain="TIGR02423"
                     /aSTool="tigrfam"
                     /description="protocat_alph: protocatechuate
                     3,4-dioxygenase, alpha subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1608_0036"
                     /evalue="9.90E-64"
                     /identifier="TIGR02423"
                     /label="ctg1_1608"
                     /locus_tag="ctg1_1608"
                     /protein_end="193"
                     /protein_start="10"
                     /score="212.7"
                     /tool="antismash"
                     /translation="TPSQTVGPYLSLGLLREDWTHLVPPDHPRAIRIEGTLYDGAGEPV
                     TDGLVEIWQAAPSGRYDHPADDREELPLEEGFHGFGRSGTEDGGRFSFVTLKPGPVPGP
                     DGATQAPHIMVAVFARGLLKQLITRIYFEDEPEANAEDPVLRSIGDERLRKTLIAGREG
                     ESRYRFDIRLQGEGQTAFFK"
     PFAM_domain     complement(21840..22274)
                     /aSDomain="Dioxygenase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00775.23"
                     /description="Dioxygenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1608_0142"
                     /evalue="4.60E-18"
                     /label="ctg1_1608"
                     /locus_tag="ctg1_1608"
                     /protein_end="184"
                     /protein_start="39"
                     /score="65.4"
                     /tool="antismash"
                     /translation="AIRIEGTLYDGAGEPVTDGLVEIWQAAPSGRYDHPADDREELPLE
                     EGFHGFGRSGTEDGGRFSFVTLKPGPVPGPDGATQAPHIMVAVFARGLLKQLITRIYFE
                     DEPEANAEDPVLRSIGDERLRKTLIAGREGESRYRFDIRLQ"
     CDS             complement(22391..23125)
                     /locus_tag="ctg1_1609"
                     /transl_table=11
                     /translation="VQHEPAQERRGILVPQEDELEQPPYLYPDYVGTRLRAPKEPLIIL
                     PKTLSDITGPIYGHHRPGELDNDLTRQHEGEPQGQKIIVHGRVLDGDGRPVRNTLVEIW
                     QANAAGRYRHKVDQHPAPIDPNFSGAGRTLTDDDGYYRFVTIKPGAYPWQNHYNAWRPA
                     HIHFSLFGRAFRSRLVTQMYFPGDPLFFQDPIFQSVRDEKARRRMISSFDLEATIPEEA
                     LGFRFDIVLEGRDATPFERPHA"
     aSDomain        complement(22406..23062)
                     /aSDomain="TIGR02422"
                     /aSTool="tigrfam"
                     /description="protocat_beta: protocatechuate
                     3,4-dioxygenase, beta subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1609_0037"
                     /evalue="1.00E-110"
                     /identifier="TIGR02422"
                     /label="ctg1_1609"
                     /locus_tag="ctg1_1609"
                     /protein_end="240"
                     /protein_start="21"
                     /score="366.6"
                     /tool="antismash"
                     /translation="QPPYLYPDYVGTRLRAPKEPLIILPKTLSDITGPIYGHHRPGELD
                     NDLTRQHEGEPQGQKIIVHGRVLDGDGRPVRNTLVEIWQANAAGRYRHKVDQHPAPIDP
                     NFSGAGRTLTDDDGYYRFVTIKPGAYPWQNHYNAWRPAHIHFSLFGRAFRSRLVTQMYF
                     PGDPLFFQDPIFQSVRDEKARRRMISSFDLEATIPEEALGFRFDIVLEGRDATPFE"
     PFAM_domain     complement(22430..22972)
                     /aSDomain="Dioxygenase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00775.23"
                     /description="Dioxygenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1609_0144"
                     /evalue="7.80E-56"
                     /label="ctg1_1609"
                     /locus_tag="ctg1_1609"
                     /protein_end="232"
                     /protein_start="51"
                     /score="188.5"
                     /tool="antismash"
                     /translation="ITGPIYGHHRPGELDNDLTRQHEGEPQGQKIIVHGRVLDGDGRPV
                     RNTLVEIWQANAAGRYRHKVDQHPAPIDPNFSGAGRTLTDDDGYYRFVTIKPGAYPWQN
                     HYNAWRPAHIHFSLFGRAFRSRLVTQMYFPGDPLFFQDPIFQSVRDEKARRRMISSFDL
                     EATIPEEALGFRFDIVLE"
     PFAM_domain     complement(22982..23074)
                     /aSDomain="PCDO_beta_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12391.10"
                     /description="Protocatechuate 3,4-dioxygenase beta subunit
                     N terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1609_0143"
                     /evalue="1.90E-11"
                     /label="ctg1_1609"
                     /locus_tag="ctg1_1609"
                     /protein_end="48"
                     /protein_start="17"
                     /score="43.6"
                     /tool="antismash"
                     /translation="DELEQPPYLYPDYVGTRLRAPKEPLIILPKT"
ORIGIN
        1 atgaaagcgg tactgctcac tggtcatggc gggctcgaaa aactcgagta cagagaggac
       61 atccccactc ccagtcccgc ccccggagag gtgctgataa aggttggtgc tgccggggtg
      121 aacaacacgg acatctggac ccgcgagggt gcctacggaa cagagattga ctcggaagcc
      181 acgagcggct ggcgccgggg gaagccgatg gagtttccca ggatacaggg catggatatc
      241 gcagggcgca ttgcagaggt tggcgaaggc gtcccgaggt cgcgcatcgg ggagcgggtt
      301 ctcgttgatt tcgtgctccg ctccggcgaa ggagatgagg ggcttgtaga ggctgatctc
      361 gtcggcagcg agcgtgacgg ggggtttgcc gagtatgtcg ctgttcccgc cacgaatgcc
      421 gtagccgtcg aaagccctct cagcgacgag gagctcgcca ccttccccac tgcttacctt
      481 accgccgagc acatgctcaa ccgggcgagc gtggcggaag acgaaaccat atttgtgacg
      541 ggagcctccg gaggcgtcgg ctccgccctc ttgcaactcg cccgtctgcg cggtgcccgg
      601 gtgatagccc tggtgggggc aggcaaagag aacaaagcgt atgagctggg cgccgaaagc
      661 gtggtaacgc gaggtacacc cgacttgccc gcggccgttg caaaagccgc agatggacac
      721 ccggtcgacg tggtcgccga tgtggtcggc ggagaggtct ttctggatct gttgcgcatc
      781 ctaaggcctc tgggacgtta cgtaacggcg ggggccatcg ccggccccct ggtgcggctg
      841 gacctcagaa ccgtctacct caagcatctg cagctgatcg gctcaacggt cggcacgcgc
      901 gcggagttca tcgaactagt aagatatata gaaagcggga agatcaaacc ccttctggcc
      961 aacacctatc cgctctcaga gataagacgc gctcaggagg actttctgag gaaggacttc
     1021 ttcggcaaac tcgtgatcat cccatgaacg caacaggtta ccctgcttat ataccgaagg
     1081 ttgtcgcgca gcgcgccctg cacgtaaacc aaaatccttt cctcgcccct taggccgccc
     1141 gcgagctcgc cagtgccccc acggtgactc tcagcgagcc tgtccgagag accttgcttc
     1201 cggggtggca cattcatctc tgttctttca atggaagcag gtctttggag cggccttctg
     1261 gcaactaccc tcgcgaaagc cgcacgaaag tcgtggctac acgctcaatg ctctttccgc
     1321 agagccgcta ctgacacgtc cctcatctct ggagggcact cacgcatctc acccgcaaaa
     1381 ggagggtgac cgacgggatt cgaacccgcg accttcggag ccacaatccg atgctctgcc
     1441 aactgagcta cggccaccaa gcgcacgccg attctatcag gaacgaggcc gtcttacatc
     1501 cgcgggccgc ctctccggga cgcgcaccac ggcgtcccgg ccggccccga tgccggcgag
     1561 cagcatggcg ccggtgacga ggcagagcac caccaggggc accgtccacc ctccggtggc
     1621 gtcgtgcagc gccccgaaga gcggcgggcc cgcggccgcg aagagatagc ccaccgtctg
     1681 cgccatgccg gagagcgcgg cggccccggc cgcgtccgcc gcgcgcaggg cgaagagggt
     1741 gagcgccagg ctgatggccg ccccctggcc gagcccgagc aggacgacgg ggaccgagct
     1801 gagcggcccg ccgaggaaga ggaggcccag tatccccgtt ccggagagca gggcagcccc
     1861 ggcggcgagg gcgctctgcg agcgcatgcg ggcggccagg accgggacca ggagggtggc
     1921 cgggatcccg acgagctgca tgagcgagac catccacccg gccccgaccg cgctcaggcc
     1981 tccctcgccg agtatggcgg gcagccaggt gatcgagacg aagaacacta cggactgcag
     2041 ccccataaac agggtgacct gccaggcgag cgccgagcgc cacggcccgc gcggggcacg
     2101 gccgggcgcc gagcgctcgg ggcgctcctt cagcaaggga gcccacgcga ggaccgcgag
     2161 cagcaccggt acggcccaca ccccgagcgc gccctgccac ccgagccccg ccgagcgtgc
     2221 cagcggcgcg ctcagcccgg cgccgagcgc ggccccaacg ttcatcgcgg ttatgtaggt
     2281 gcccgtgacc ggtccgacgc gacgggggaa gtagcgcttt acgaagccgg ggagaaggac
     2341 gttggcggcg gctatggcgg cgccgagcac ggccgtcccg gcgaacagcg ccgcctcctg
     2401 cggcagcgag cgcaaagcta tgcccgccgc gagcagcacc agccccccga acagcgtgcg
     2461 ggagagcccg aagcggccgg cgagccgggg ggccagcgac gagaaggcgg cgaaggcgag
     2521 gagcgggagg gtggtgagca gcccggcgag cccgctggag agccccatgt cctcccttat
     2581 ccccccgata accggcccca cggaggttat ggaggcgcgc aggttgagcc cggcgaggac
     2641 gacgcagaag aacggcagag cgccccggag gaagcccgag cccttcaccg cccgaacgac
     2701 cgcccggcta ctccagcggg agcccggtgt agttctcggc gagcgaggtc gaggcggcgc
     2761 gcgagccggt gacgtagtcc agctcggcga cctgcagccg gtagcggaac tcgtcctcgc
     2821 cgtggaagcg gtggagcatc gaggtcatcc accaggagaa gcgctgcgcc ttccaaaccc
     2881 ggcgcaggca cctctccgag taggcatcca gcagctccgc gcgccccgaa gcgtagaact
     2941 ccgccagcgc ctcgcacagc acgcgcacgt cggcgaccgc caggttcatc cccttcgcgc
     3001 cggtgggggg cacgatgtgg gccgcgtcac cggccagaaa gagcctgccg tagcgcatcg
     3061 gctcgcagac gaagctgcgc atggccacga tccccttctg gaggatgggc ccctccttca
     3121 gtcgccagcc gtcctccatg gccagccggg cgtgcagctc ctcccagacg cgctcgtccg
     3181 gccagttggc cacgtcgtcg tcggggtcgc actgcaggta catgcgttgg atctccgggg
     3241 agcgggtgct gatcagggcg aacccccgct cgtggaggca gtagatcagc tcctccgacg
     3301 agcggggcgc ccgcacgagg atgccgaacc agccgaaggg gtagcgccgc tcgtactccc
     3361 tgcgcgcacc ctcgggaatg gaggggcggc acgccccgtg gaacccgtcg cagccggcga
     3421 cgaaatcgca ggagagcgcc tcctcgcgcc cgtcggggcc agcgtaccgg acggaggggg
     3481 agtcggtgtc cgccccctcc acggcgagaa cctgcgcctc gaagacgatc ttccctcccg
     3541 acgcgagccg cgcggcgatg aggtccttca ccacctcgtg ctggccgtag agcatgatcc
     3601 cgcgcccgac gaggtcttcg aagtctatgc ggtgcctgcg gccgccgaac tgcaggttca
     3661 cgccgcggtg gaaggcgccc tccctcatca tccgctctcc caccccgatc tcgttcaaga
     3721 gatccatcgt cccctgctcg agcaccccgg cccggatctc cgactccagc tcctcgcggc
     3781 tgcgccgctc cagaaccacc gactctatcc cccgcaggtg cagcaggtgc gagagcaaaa
     3841 gccccgcggg cccgcctccc actattccca cctgggtgcg catagccctc ctccgcctcg
     3901 aaccttctcg aaccgcccgg caaccatgct agcacccgtt gggaggccgg gcgcgcccct
     3961 cgaagcacgc gcccggcacg ggctcccgcc cccgccggcg ccggcggggg cgggaagtag
     4021 aagagaacgc cgtggggagg agacccggca accgcctccc tacgagctgc ggtaggcggt
     4081 gcgggcgaac tcgaccagcg gggcgggctg cacccgcgcc cttatctcca cctgccggtg
     4141 ctcctccacg gtgggcttcg agctgttggg ctcctcgccc cacaacagca caacctccgt
     4201 cccaggctcg cagaactcct cctccaccac cgcaagcgac agcatcgccc gctcgttgta
     4261 gctgtagccg gtgtaggtgg agacccccac gacccgaccg tccttctcca cccggtcgta
     4321 gggcagcgtg gcgtagttgg agagcgggag gtctatgtac tttgcgggaa gcccctccct
     4381 ctcgaagagg ctcccaaaga cgccggccac atcctccccc tcccacacca gcgtcacctt
     4441 cctgcgctgc ggagcatccg ccatctcctc cagcgcctcc ctgcccacaa agtcgtggtc
     4501 gaacttcacg aagcgcccgt agcccagctc gtagggggtg aagtagtagt cctctatcct
     4561 ctccgagtag aagctccccc cgagggaggc catggcctca taaccgtttg cgggcagcca
     4621 ctgcctgtag ggcttcatct cctccccggt gtagatggcg gggcagggag aagggatcca
     4681 gcctgactcc agggtgttgg tggcgtaggt tctggagccc acctgcctca ggccgtactc
     4741 ctcgcccgcc tccacgatta tgcccttgat ctcgtcccgc tcctcccagg ggccgaagat
     4801 ctcggcgccc ggctggccgc tcatcccgtg ccgcagcgcc cgcaccttgc ggtcgccgat
     4861 gtttatctcg tacatgctga agaacggcac ctgcgggagc ggcccgccgt tcagcttctc
     4921 cagaagctcg gcggcgttgg gaccctggat ctggtaacga taaagcctcc tgcgcttctc
     4981 ggggttcgcc gcgtaccgct cgtcccgctc gaccttcacg tcgtagtccc cgctctcggc
     5041 gtggtactgg acccagttgt gcgcggtggg ccgcccgacg aggctcaccc ggtcgtcctc
     5101 gaggccgaac aggatggcgt cgcctatgac gtagccatca tggttgcacg cgacgaactg
     5161 cttggcgttg ttcttcttga agccctcgaa gctgtttatc ccgaggtcgg agagcaaccg
     5221 cttcacgtcc ggcccctcta tgtagaggtc ggtcatgtgg taggactggt cgaagagcac
     5281 gcagctctcc ctccacgccc gctgctcgtc ccgccagttg gtgaactcgg cgggcacccc
     5341 agggaaggcg tagggcccta tctgcgagtt gcgcagcagc tcaaccgggc tcttcgcctc
     5401 cgaaagcaca tcctccagac tgcgtcggtc catgatctcc ctaaacctcc tcctcgcaac
     5461 accccttgct cttttgcgcc ccgcggtcac cgctcaacct acatcggcgc acctcctgcc
     5521 gcaaatatcg ttttcattgg cccccatatc ctccggatat acccggcgcg ccgcgctccc
     5581 cgccgctccg cgcccggaag gccaggccac gccccgccgc cacggtgttt ttgagcagcc
     5641 aaacgtcggt gatgggcccc accccgcccg gcacgggggt gagggcctcg gccttccggg
     5701 cgacgctgcc gaagtccaga tccccgacca gaagggtcct cccgctgccc ccggggtccg
     5761 caacggggtt tatgcccacg tccacggcga tcaccccctc cctcacgtag ctctcgtcta
     5821 tgagccccgc aacccccgcc gccacgatga gcgcgtcggc cttaagggtg tgctcgcgca
     5881 gccggcccgc ccggtaggcg ttcgcgtcgc aggagatcac cgccgctccc cgggcgaaac
     5941 ccagcgagac ggccggcttg ccgacgttgt tggaccggcc cacgaccacg accgtgctgc
     6001 gggggtagaa ctcctctggc ggcctccccg agcgctccag gtagcggtcg agcaggtaga
     6061 agcacgccgc gggcgtggac ggcacgtacc gcggccttcc cagggcgagc agccccgcgt
     6121 tcaccgggtg caccgcctct atgtccttca gagggtccag cgcgctgaag accgccggct
     6181 ccgagatgtg ccccggaagc ggcctgagga cgaggatccc ggagacccgg gggtccgcgt
     6241 tgagcttgcc caccaccgcg agcacgtcgg cctcctcggc ctcccgcgga agccgctcgc
     6301 acacgtagcg gcagcccagc tccgcggcaa gcccccccac ccggcgctcg taggcccgcg
     6361 cggcatagtc ctcgcccacc agcaccgtgg caagcccagg cctcacgccc cgcgcggcga
     6421 gcccctctac ctccgaggcc accctcttct tgagctcccc cgcaatgggc ctgccgtcta
     6481 tgacgcgcgc acccaataga gccccctacc ctccgccctg cgccatcttc tcgcgcgccc
     6541 ggcgcgcagc ctcgacaaag cggcgcgcct cgagcgcccg ctccccctcc ggctcgttgg
     6601 cctccacgag ctcagccgcc gcccgcaccc ccgcctcggc cagaagcgcc ccggccaccg
     6661 catccccctt gaggttgggg ttgccctcga gcgccagccg gccggcgagg cggcagacct
     6721 cggcgccgat cctggccatc tcgagcggca ccccggccgc ctccccgagc gcctccccga
     6781 tgcgctcccg gcgcccctca ctcccgcgcg gcaggcggta ggcggcgagc acccgaccga
     6841 aggcctcggc atcggcgcgg gcgagcggtg cgacctcctc cctgagagcg tccgccctct
     6901 ccgcaagctc ccccgcggag gagagccggg cggccatggc ggcaaggccc gcggccatgg
     6961 ccaccgagac cgcagcggcc gccccaccgc ccggggccgg ctccccggag gagagcgcct
     7021 cgagaaagcg ccccagcggc atctgcaggt agtccggtat cccggaagcc ccgccccgcc
     7081 cgctcaaaac agccccacta cgttgccctc cccatcgagg tctatcctct cggcagccgg
     7141 atgcgccgaa aggcccggca tggtgcgcat ctgcccgcag atggggtaga tgaaccccgc
     7201 cccaacagag gccctcacct ccctcaccga gagcttccag cctctcggtg cccctttcag
     7261 agcagggtcg gaggagaggg agaggtgcgt cttggccagg catacgggaa gcctcccaaa
     7321 cccagcccgc tcaaagccct caagggctct cagcgcctcg gcgtcgtact ctaccccctc
     7381 tgccccatag acctctctgg ctatggtctc tatcttctgc tttagcggca tctcaagcgg
     7441 gtagagaaag cggaaggagc cgcctcctcc ccttcttctc tccctctcgt tctcctctat
     7501 cgtctcctcg agggcccgcg caagctctac cgcccctttc cctccttcgg tgaagtggcg
     7561 gcacacggcg cacctcgccc ccacctcctt tgccgcctcc tctatggctt tgtgctccga
     7621 tgggtggtct gtgggaaagg cgtttatggc cacaacggcc ggaaccccgt gcagctttat
     7681 gttctctatc tgctttttga ggttctcggc ccccgccaga acgtcctgcg ggttctcctc
     7741 aagcagctct tcgggaagcg gagcgccggc ctttatctgg tagcgccccg agtgggcctt
     7801 gagcgcccgc accgtggcaa ccactacggc agcgtccggc tcaaggcccg agatgcggca
     7861 ctttatgttg aagaagcgct ctgcccccat gtccgcccca aagcccgcct cggttatgag
     7921 gtagtccgcg gtgcggatgc ctatgaggtc ggcaacgacg gaggagttgc cggtggctat
     7981 gttgccaaag ggacctgcgt gcaccagcgc aggggtgccc tcaagggtct gcatgaggtt
     8041 gggctttatg gcctccttga ggatcacagc catcgcccca gcccctctta cgtcctcggc
     8101 gcttacgggg ttgccctccc tgtcgtgccc tatgactatc ctgccaaggc gctccctcaa
     8161 gtcctcaagg gagctggcaa gggcaaggat ggccatcacc tcagaggccg ccgttatgtc
     8221 aaagcccgac tggcgcggga cgccgtccgt cctggcccca aggcctatga cgatgttcct
     8281 caggctgcgg tcgtttacgt ccatgacccg ccgccagctg atggagtggg gctctatccc
     8341 aagcccgttt ccgtggtaga ggtggttgtc tatcatcgca gcgagcatgt tgtgcgcctc
     8401 tgtcacggcg tgcaggtcgc ccgtaaggtg caaattgagc cgctccatgg gcacaacctg
     8461 cgagtatcct cccccagcag ccccaccctt tatcccaaag gcagggccca tggaggcctg
     8521 ccttatggcg atggtggccc tcttgcctat gtgcgagaag gcctgcccca aaccaacggt
     8581 ggtcgtggtc ttgccctccc caagaggggt tggggttatg gcagagacaa ggatgtactt
     8641 cgcctttggc ctctccgaga gatcctctat ggcacagagg tccaccttgg ccacgtgcct
     8701 gccgtagggc tcgaggtggc gctcttctct gaggcccatg gagcgcccca cctcttctat
     8761 gggcagtagc ttcgctcctc ttgctatctc gaggttggaa agagcctccc ccaccctcta
     8821 tcccctcctt ctcttctcgc cctctctttg cgccatcttc ttctcttcga gtacccgcca
     8881 cccggcgggg ttcccgcgag tctcgccaat attgtcaaca atattgttca aaaaatacca
     8941 caggcgtgga gaaaagggaa gcccggcggc gcgggaactt cgccgccggg gcgcctcgcc
     9001 gtcacccctc ctgtcatcgg gaggccggcc tcccgccctc tcctgcgcct tcgcgacgcc
     9061 cggcggcgta cgcggcgtag gcgtcgaggg atgttggatc caggagggaa tcccggctcg
     9121 ccacctcgtc ggggcgggcc ccgagaagga tgcgtttgac cggcacctcg agcttcttct
     9181 gggagagcgt gcggggaacg gagggcacgg cctcgatggt gtcggggaca tgccggggag
     9241 agagctcgcg gcgtatggtg gaggagatgc ggtcgcgcag cccgtcgtcg agcgcggcgc
     9301 ccggcgcgag gaccacgaac agcagcagct cgccgggccc gccctcatcg tcctcgaggt
     9361 ggacgacgag gctgtccctc acctcctgca gagactcgac gacggcgtag atctccccgg
     9421 tgccgaggcg aacccctccc cggttgagcg tcgcatccga gcggccggag atcacgcagc
     9481 ttccgcgctc ggcaaagcga atccaatccc cgtgacacca gacgccgggg aagcgctcga
     9541 agtacgccgc gcggtagcgc ctgtcgcccg ggtcgttcca gaagccgacc ggcatcgagg
     9601 gcatcgggga gcggatcacc agctctccga actcccccac caccggcctg ccgcgctcgt
     9661 cgaaggccgc agcgtcgacg cccaggcagg ggcccgagat ctctccgcga tagacgggct
     9721 gcagggggct gccctgcacg atccccgtgc acacgtcggt tcccccgctg cctatgttca
     9781 gcagcacgtc cggaccgagc tgctcgtaca cccagtcgaa gccctccggg ggcagcgggg
     9841 agccagcggc ccccagctgc cgcagagagg agaagtcgaa gctttttccc acggcgagcc
     9901 ccgccttccg gcaggccatc aggaacgccg gggcgacgcc cagcatggtc gcgccgaccc
     9961 gctcggcgag gcgccactgg aaggcgagat ccggatagac cgggttgccg tccatcgtga
    10021 cgatcgccgc ccgcagcagg agcgcagaga cgagggcgtt ccacatcatc caggcggtgg
    10081 tcgtgaacca cattagccga tctccggggc gcaggtccca ggtcagcccg aggttcttca
    10141 ggtgctcgag gaggatcccc ccgtgaccgt ggactatcgc cttgggcttg ccggtggtcc
    10201 ccgaggagaa cagtacgtag agggggtggt cgaaggcgac cggctcgcag gcgaggggcg
    10261 cggcctccga gagcagctcc tcccaggcga tggccccggg gagcgcatcg tttgcgcctc
    10321 cggcgtaggg cacgtgcacg aggtgctcca ggttcggcag ggcctcgcgg atagccgcca
    10381 cctccgaccg gcggtcgacg aacctgtcgc cgtagcgata gccggcgacc gcgagcagca
    10441 ccttcgggtc gagctggccg aagcggtcga cgacgctccg cggcccgaat tccggagcgc
    10501 acgtcgccca caccgcgccc aggctggcgg tcgccaggaa ggcgacgacg gtctccggaa
    10561 cgttcggcag gtaggcgacg acgcgatcgc cgggcccgac gccgaggcgg agcagcccgg
    10621 cgcgggccct cgccacctgc tcccgcagct cgccgaaggt cagctcgagg gggcccctgc
    10681 tctgggagtg ggcgatgatg gccgtccgcg cgtcgtcacc cgcgggcgcg aggatcctct
    10741 ccgcgtagtt caggcgcgcc cccggaaacc agcgcgcgcc gggcatctcg cgggaagcca
    10801 gcgcgcgctg cggcggggtg tacgaccgca cgccgaagaa gtcccagatc gagctccaga
    10861 acccctccag gtcctcgacc gaccagcgcc agagatcctc gtagccgccg aacccgagcc
    10921 cgcgctccgc gcgcaaccag cgcacgtagc gtccgatctc ggtcttctcc aggacgtccg
    10981 gcggcggagc ccagagcacc tcgcccatca gagccactcc aggatctccc ccaccacgtt
    11041 caccaccgcg tccggccgcc ggcgctccgg caccccgtcc agctcgcggg cgccgctgat
    11101 gccgctccgg accaggatgg tccgggaccc gcccatccgg cccagcgcga tgtccatatc
    11161 caggtcgtct ccgatcacgg ctatctccgt cgagtccaac ccgaggcggt cgcagatggc
    11221 gcgcaccgcg ggccgcgagg gcttcccgac gatcacggga cgtgcgcccg tagccttcgc
    11281 cagcgccgcc gtcagcatcg cgccgcggct gaagatcatg ccgtccgatc cccagtagcc
    11341 gggaccgtag ttcgccgtga gaaggcgcgc cccgcgcgtg atcgcccggg ccgccctctc
    11401 gagcgcttcg aaatccacct cgtttacgtg ggtgacgaag accacctcgg catcctcgcc
    11461 gtccgtgagc cgcacgccgg cctccagcag gcgctcgcgg acggtcccgg acccgaagac
    11521 catcacccgc cccgacttgc gccggcggga gaggtacccc agagcgctgc agacgggcgt
    11581 cagaacctcg tcgtcccgga cgggaagccc gccctcgcgc agcccttccg cgaactcctc
    11641 ggggcgcagg tgcgtcccgt tggtgaagag cacgagcggg cgccccgagg cgcgaatgct
    11701 cttcagcacc tcaggcgcgc ccggaagggg gcgtgcccgg aaggtggcgt cgcggtgcac
    11761 gagcgacccg tccacgtcga agacgaagcc gcggatatcc ctaagatcca tggcgccaga
    11821 caatggtgtc ccccgtacgt tcatcctcca gcttcaagta ggagatggac ttgcgtttgg
    11881 agagctcgtg caggagccgc acgagcgggg cgcgcccggg acgcaccagg ggcgcccgct
    11941 gcctgccgcg ctcggcgacc atggcgtcca cctgctccgc cggcatcgta aggcgcagca
    12001 ggagctcctc gtcggacagc ctgcggccga aacgctcgcg ggcaccctcc agcgtgatcg
    12061 gcttgaggtg cttcagctcg tccgctcgcg gcatcgagag cacacggtcc gccacatcgg
    12121 cgtcgaccgg agccggagga tcgtagtagt ggccgaggaa gtagcgcacc atctcgtcgg
    12181 agaccttcga ccagcgctcg ccggagatga cgttcatcac ggcctgggtg gccacgaact
    12241 gcgaaacagg ggtcaccatt atcgggtagc ccatctccgc gcgcacgcgc ggcacctcct
    12301 ccaggaccgc gtcgaacagc tccggcctcc ccagctcctg cagctgccgg cgggtcgtgg
    12361 agatcatgcc ccccggcatc tggtgccgga agtaggcgcc gtcgaactcg cgcggggtac
    12421 cgggcggcag cccccgctcc ctcgccagct cgtggaagta gtccgagacg acaccgaggg
    12481 cctcggtgtc gaggtcgcac gagagcccct cggcctcgat gttgcgcagc gtggctccgg
    12541 cgggcgggtt ggagctcccg ctccccaggg gctccaccgc ggtgtgcagg atccgcacgc
    12601 cggagcgcag cccctcgacg taggcgaggg ggccgagccc gatcgtgcag tggctgtgca
    12661 gctcgaccgg tcgcggcgcg aaccgctcga taaagccggg gatgagggcg cgcaccgcat
    12721 ccggggtgag caggccgccg gggtccttga ggtagagccg gtcgatgtcc tcggagcggg
    12781 ccgccgcggc agcccgctcc aggtagtact cgtgggtgtg gaccgggctg atagagtacg
    12841 tcagccccac gaccacctcc tcgaagccct cctcgcgggc gatgcgggcc atccggagga
    12901 gcgcccccgg atcgttggag gggtcgacga tctgtatccg gcgcatgccg ttgcgcaccc
    12961 agcaccggaa ggcgaggcgc atgagatcct caccggcggg aacccagcgg ataaagcgca
    13021 taccggtggt gataaggccg agcggcgtgt tcggcatggc ggcgctgacc aggcggatcc
    13081 gctcccacgg atcctcgcgg tgaaagcgga cggagatccc catgtgcgtg ctcgaggtga
    13141 agtccagggc gtggaagccc acgcggtcca tggtgggagc gatggcgagc acgtcctggg
    13201 tggtgagccc ggtggcggac cacaggctct ggttgccgtc tcggagggtg gtatctacta
    13261 tgtccacaga accgctcatg ccgcaagcac cgcctcctcg agccaccccg tgctcaccgc
    13321 ggccccggcg aagtccgggt gggcgatgat gtggctcagc agatcccggt tcgtcggtac
    13381 gccctccacc ctcaggccgg cgagggcctc tctcatcctc tccgccgcct cgctgcggtc
    13441 gttcgcgaag gttattagct tcgcgatcag cgagtcatag taggggggca cgagggttcc
    13501 ctcctcgcaa tgggtgtcga cgcggagacc gggaaggttc ggcaccgaga aacgggtgat
    13561 cctaccgggg gtgggccgga aaccgtgggc ggcgtcctcc gccgtcagcc tgcactctat
    13621 cgcgtgcccc tcgaacccca cctcctcctg ggtcacctcc agcggctcgc ccgcggcgat
    13681 ccggatctgg tcggccacaa gatcccggcc ggtgatggcc tcggtcaccg ggtgctccac
    13741 ctggatgcgg cagttcatct ccagaaagaa gaactcgccg ctccgggcgt cgaccacgaa
    13801 ctccacggtc cccaggttgc gatagccgat ctcggcggcg aagcgaacgg cggccgcatg
    13861 gagcgccgcg cgcgtgccgg ggtccagggc aggcgcagga gcctcctcga cgatcttctg
    13921 gtagcgtcgc tgcacggagc agtcgcgctc cccgaagtgg acaacgccgc cgtgctcgtc
    13981 cgcggccacc tgaacctcga cgtggcgcgc gcggcgtatg aagcgctcca cgtacaggcg
    14041 atcgtcgccg aacgccgccc ccgcctccgc cagggcgacg ccgaacagcc gctcgagctg
    14101 cccccgatcc caggccagct tgatcccccg cccgccgccc ccggccgcgg ccttcagcag
    14161 caccgggtac ccgtgggcct cggcgaagcg cagggcgtcc tcgagggcgc gaacctcgcc
    14221 gccggggacc accggaaggc cggcggcggc agcggtctcg cgcgagcgga gcttgtcccc
    14281 cgcgagctcg atgaccccgg ccggcggccc gataaagcga aggccgtgct cccgggcggc
    14341 ggacgcgaga gcggggttct cggagagaaa cccgtagccc gggtggatgg cgtcgcagcc
    14401 ggtacccagc gccgcctgca cgacggcacc gacgttcagg tagctcctcg ccggcgcacc
    14461 cgggccgatg cacaccgccc ggtcggccat gcgggccgcc agcccgccac ggtctacctc
    14521 cgaggcgccg accaccacct ccagcccgag cctgcggcag gccctgatga tccgcaccgc
    14581 gatctcaccc cggttcgcca cgaagacccg ctttatcccc atcactcggg ctccacccgg
    14641 aacagcggct gcccgtactc cacgagggcc ccgttctccg cgcacacctc gactatcctc
    14701 ccggacaccc cggccctgat cgagttcatc atcttcatga cctcgatcag gcacaccacc
    14761 gtatccggct cgacgcggct gcccacctcg acgaacggct tcgcccccgg ggcctcggcg
    14821 cggaagaagg tgccgaccat cggcgcttct atggctacgg tcccgtccgg agtgggggcg
    14881 gcctccgcgc cccgcccgcc ggctgctgcg ggctctgcgg aagcgtgtgt tttctcctca
    14941 gatgctggcc tggccttctc ctcctccccg gaggcttctt cgaccggcgg cgcaccgccg
    15001 cgccgcacgt acagccgcag cccgttggtc tcgatccgca gctcttccag gtcggattcg
    15061 tcgatgatcc tcaggatctc gcgaacatcg tcgtccgaga gcggcattca ggacctgcct
    15121 tcgtcgtcgc gaaccacacc gaaggttccc atgaccaact cgatggccga gcgagcccgg
    15181 ggtagatcct tccccgcctc cggcctgcgg ggcgcggtgg tgaccggccg ggactggagc
    15241 acgtacaagg actcgggcag ctcccgcccc cgggagatcg cccactcgat gtcctggggg
    15301 gcgccgaagt ggcgctccac gcggcgagcc acctcgacca gcgcccgaag gcacgcctcg
    15361 tccaggcagg ggacctcccg gcgcgcctgc tccacctcca ccgcccgcac cccggcggaa
    15421 cccggatccg ggcggtactc caggtgcttg cagccgacgg accggcgcag cacctctccc
    15481 gtcaccttgc tcacgcggta ctcgtccggg gtcacctccc cggccaccac cgcctcgccc
    15541 agcccccagc tggcgttcac cgcgacggtg ctggggtctc cgttgagcgg gttgcaggtg
    15601 aacatcacgc cggccacctc ggcgtcgacc atcatctgca ccgcgacgcc catggccggc
    15661 tcgcccccgc ccgcggacat tctggcccgg tagctcagcg cctcggggct gtagaggctc
    15721 gcccaacagc tgcgaaccgc cgcgcagacg tcgtcgaccc cgcgcaccca caggtgcgtc
    15781 ttctgctggc ccgcgaacgt ggcctgctcg ctgtcctcgc ccaccgcgct ggagcgaacc
    15841 gccaccgggg ggctctcctc gccggagagc tctgcgatct tgcggtaccg gcgctccacc
    15901 tcgccgacga cctccccggg aaggggagcc gagagcacgg ccgcgacgag ctcctcggat
    15961 acacgccgca gggcgctcat atcatccggg tcgagggccc ggaggctccg caccacccgc
    16021 tcccggatgc cgttctcctc caggaaaagc gcgaaggcgt cggtcgagat ggcgaagccc
    16081 ggcggcaccg ggatctcgct cgaaagcagc tcccccaggt tcgcgctctt cccgccaaag
    16141 cgcggctcct cggcccgccg caacctgtcg aggggggtgg tgtacccggt cgcggccgag
    16201 ctaaccatcc aggatcacca cccggccgct cgtcccgtcc acccgcagcc gctgcccggt
    16261 cctgatcctc gccgtcgccg tgccggtgcc gaccacggcg ggaagcccat actcgcgcga
    16321 gacgatcgcc gcgtgcgaca tgatcccacc gatatcggtc acggtcgcct tgatcttgct
    16381 gaagatggga gcccacgccg gcgaggtgga ggtgcacacc aggatctccc cgccgcgcac
    16441 ctcggagatc tcgtcgagcg agcgcaccac ccgggccaca ccctcgacct cgccggggga
    16501 cgccgcggcg ccggagagct cgttgccccc tccatcgcgc tgcgcccgcg cccactcctg
    16561 cagctgctgc ggcgtgaccc cccacagcat ggtgatcgcc ggatccacga ccgcctcggg
    16621 catccgcccc agagcgggcg gcggcgtcca gccctccaga cgcttcaaga gctgcttgcg
    16681 gcgcgccacg atctgcggcc agtgacgcgg ccccagagcc tcccctccgg tcgaccaggt
    16741 gagggcaagc tcctcgagcg cctgcatcgc ctcgtagcgc gaaagctgga agatatcctc
    16801 gctctcctcg aggaacccgt gccgcgcaag caacgcgccg aactcgcgga tcttgttgaa
    16861 gaaccgcgac tggaaccaat aatcgcagta gaacttgtgc tcctctacgt aggggaacac
    16921 cttgcgcgag agcccgagca gctcccgaaa cgttcgccgc gcatcctcgt cgaggagcgc
    16981 ctcgtactcc cttacgagct ggtcgcgccg ctcggcgagc tcgcgggtgg gccgctcgat
    17041 atcctcgccg gcctgcagcg ccgcgatgtg accgacgagc gagctgtagg ggatgctggg
    17101 atcgtcgtgc cagctgccgt agtagtggta cagcccatca cctgtcccca tgttgaacca
    17161 ggggtccttg accttcccga gctccttgag ccagcgccgg cccgcatcgc tgcgcgcgag
    17221 ctccgcctct atctcctccg gagagcgccc ctcgcggaag gcccctgcca cgccgagctc
    17281 tatcgccaga cgcgccagcc ggcgcaactc cgcgtcgggg cgaaagagaa ccacgtcgat
    17341 gccggccacc atctgagaga tgtgctggtc gggtatgtcc gggagagcct gcttgcagaa
    17401 ctcggagaaa gtcaggtagg caccgtagcc gagcagcaga aactcgaagt ggtactgcca
    17461 catccgctcc acgcagtcga gcgcccggcg gtagctcgcg agcagcgtcg cccagctggg
    17521 ctcccctccc tcgaaaacga ccctctcggg ctcgtactcg ggaagctcgg gaacggggat
    17581 ctccgcgacc tcccggttca gcgcctccat cctctcccgc caccgggcgt agagctcgtc
    17641 ccagttctcg tagtagtagc cagcacgctg ctggaagaag cgcgaccgct cggctatctt
    17701 ctcggggtcg gtcacagggt tgggcgagat gtagacgtag ccgttgacga cgcggtagtc
    17761 cacacccatc gcccccggaa ccgcgaacgc ccggttttgc cagccgccga gggcatagta
    17821 aggggtgtcg acctcgacca tgtcgaaggc cggcatcggc accggaaagt gcatcgagtt
    17881 ccagaaccac aaccggttct cgtcgtgctc gcgccgccgc tcgtcaaaga gcgcccaggg
    17941 cggatacatc tcctcccatc cctcgcaccc ctcgggcgtc cggatcgaga aggggctcgg
    18001 aaacccctcc agcctctcag gttcggtgac catcccggca ctcctccttt cccaacctgc
    18061 cgccctgaat tctcttcagc acgccgtcac ggagcaaata ctcgttccgt atgccagata
    18121 tacctgcccc gtataccaga tccccacccg tcatcccgtg agtccgccgc cgctatcccc
    18181 ggctcctctt ctcttcgcgc acccactcga gggtcctctg caggtcgttg aaggtgtaga
    18241 ggtgtagccc gcttatcatc cctccccctt cgtctgtgcc cccagaagag gcaaagaacc
    18301 cctccctgct cccctcctca acaagctcct ccaaaaaccc tcccggctcg tacaccagcg
    18361 agagggcgct cctccttctg cccggagaaa gcagcctcag caaggacttc gcccgctgct
    18421 ttctcagaaa cctggccgag tcccctatgc ctatcttcgc cgctacgcct gcaagcctct
    18481 tcgggtctat gggcgcggca acccccacaa ccacgggcag cccaacccca agctctctta
    18541 ccctccttgc ccacaaaagc accttctttg cctcaaagca gagctggctt accacgtagc
    18601 tggcatagag ggctttcttc cggagcgccc gctcaagctc tgcccgctct atggaggggt
    18661 gcccttcggg gtagccggct atccccaccc gctcaaaggg cctgcccagc tcctcgagcg
    18721 cttcgaggag ccccaaggcg tcatggaagc gcccccttgg ctccttcgca tcccccccta
    18781 tgacaaacac ctcctcaacc cccgcctcct tgaggcgcgc cacgatctct tcgaggtgat
    18841 gctcgtcttc tatgagcctc gcagagaggt gcggcacaac gcaaagagat gaaggctctc
    18901 ctcctcttct tcttgctttt gcgccaagcc tctctgtgag ggcgatcgtc ggctctatgc
    18961 cccgtgtggg ggaggcggtt atggtgatgg tggtcttctt ctgctcttct gctcttcggg
    19021 agatgagcca gcgctccacc gcctcttctg tgcccgccag cgggatgacc tcgtagcgga
    19081 tatgttgcag gagatcggcc accacccgat ccaaccccgc cccaccgctc tccgacctct
    19141 cacccatgga tcgcaccacc cacagaaacc gccggcaaag ctcctcctct cataaaacgc
    19201 ctcctggtac gggagtctaa cttatatacg acaatattgt caacaaaatt gactacgcat
    19261 ctcccctccg cagcggcagg ggtatgggag cgtcagccgc cggggtcttc ctggccggag
    19321 atggcgcgct gggcgacggc gaaggcggag ttggcggccg ggacgccgca gtagatggcg
    19381 ctgtggagga tgacctcctt tatctcgtcg ggggtcagcc cgatcctgag ggcggcccgg
    19441 acgtgcatct ccagctcgtc cagacggccc gcggcgatga gcgcggtcat ggtcatgcag
    19501 ctgcgggtct tgcggtccag gccggggcgg gtccagacct ccccccaggc gtagcgggtg
    19561 atgaagtcct ggaagtcggc ggtgaagtcc gtcgccgagg cgagcgcccg gtccacgtgc
    19621 gcgtcgccga gcacctccct ccggacgcgg aggcccctct cgtaggcggg gtcgctcacg
    19681 acgacctccc ctccagcacc ggggagaggt gctccagcag ggcgcgggca aagggctcgg
    19741 gccgctcgat gttggccagg tgcgccgccc gctctatgac caccgtccgg gcttccggga
    19801 tggcctccct gaggcgctcg ccgtgctccg gaggggtggc ggggtcgtcg gagcccgaga
    19861 tcaccagggt gggggcctgt atcctgccca gccggtctct gaggtccatc tcccttatgg
    19921 cctcgcagca cccggcgtag ccctcggggg gcgttgcggc cagcatgcgc ttcgcccgct
    19981 ccacgtcctc ggggcgctcc tggtggaggg cgggggtgaa ccagcgctcc acgacgccct
    20041 ccaccagcgc ctccatcccc tcgctccggg ccacccgcgc ccgttcgtcc cacagctccc
    20101 tcgggccgag cagggccgag gtgcagcaga gaacgagccg ctccacccgc tccgggacct
    20161 cgctcgcgac ccacatcccc accatccccc cgagcgagag gccgcagaag gagaagcgct
    20221 ccacgccgag cccgtcgagc atggcgagca cgtcctggcc gagctccgcg atggagtacg
    20281 ggccgggcgg caccggggaa ctcccgtgcc cccggtggtc gtagcgcacg agcctgaagc
    20341 gctccctgag cgcggggacc tgcgggtccc acatccggtg cgtcgtcccc agcgagctgg
    20401 agagcaccag gaccggggcg tccgccggcc cctccacgac gtgatgcagc tctaccgtca
    20461 tcgctgtccc tccctccggt acatctctag cgcccggtcc acgaactcgt ccgccgcccc
    20521 caggtagcgc gccgggtcga gggccccttc gatctcctcc tccgagagcg cctcccgcag
    20581 ccggggctcc gccaggatct cctcgcgcag cgtccccccg ccctccgcga cccgccggca
    20641 ggcggcctcg accagctcgt gggcctccag cctccccagc cgctccgcgg ccagcgtggt
    20701 cacgttctcc gccaggatca aaccctccgt gaccgccagg ttctcggcca tcctcccggg
    20761 acggacctcc agcccctcca gggcctcgcg caccgcggcg gcggccccgc ccgtgagggc
    20821 cagggcgccc gagagggcct cccactcggc gtgccaggcc ccggcggccc gctcgtgctc
    20881 ctgggccagc gagccgtaga gggtgcgggc cagatcctgt acccgccggg cgttcgccga
    20941 ggcgaccacc gagaggatcg ggttccgctt gtgcggcagg gtggaggagc cgccacgccc
    21001 gcctcccgag ggctccgccg cctcccccac ctcggtctgg gccatgagga tgacgtcgag
    21061 cgccaccttg tgcagggtcc cggcggcgag ggcgagcgcc ccgccgagct ccgccaccct
    21121 gaaccttgcc gcgtgccacg gcagggcggg ctcgggcagc gcgagcagcc gggcgtactc
    21181 ccgcagcacc cgcgtccccc tctcccccag agaggcgagc gtcccggccg ccccgccgag
    21241 ctgggccgcg agccccctct ccctcgcctc ccggagaacc ctgcgggcct cgagggcggc
    21301 gacgagccac ccggcggcct tcaggccgaa ggtcgtgggg agcgcctgct gcagcagcgt
    21361 gcgccccgcc acgagggtct cgcggtgctc ctccgcgagg cgggcgcacg cggcgcagac
    21421 cccgtcgagc tcccgcagga tcaggcccag cgcctcccgc gagatcagca tggcggcggt
    21481 gtcggtgatg tcctggctcg tcgcgcccct gtggacgtgg cgggcggcct cgccggggac
    21541 cgcggcggtg agctccttca ccagcgccgg gacggggttc cccgctgccc ggccccgctc
    21601 cccgagctcc tccgggtcga gctccagttc cctgcagcgg cgggagatct cctccgcggc
    21661 ctccggcggg accaccccgg cccgcgcccc ggcccgggct agcgccccct ccgcctccag
    21721 catcgcccgc agccacgccc ctcccgagac cgcctcgcgg aagcgctccg ggacgaagat
    21781 gggcccgaag agctccccgc tcatggggag agcttgaaga aggccgtctg cccctcgccc
    21841 tgcaggcgga tgtcgaagcg gtagcggctc tcgccctccc tgccggcgat gagggtcttc
    21901 ctgaggcgct cgtccccgat ggagcggagc accgggtctt cggcgttggc ctcgggctcg
    21961 tcctcgaagt agatgcgggt tatgagctgc ttcaggagcc cccgggcgaa gaccgcgacc
    22021 atgatgtgcg gcgcctgggt ggccccgtcc ggcccgggga cggggccggg cttgagcgtg
    22081 acgaacgaga agcgcccccc gtcctcggtg ccgctcctcc cgaagccgtg gaagccctcc
    22141 tccaggggca gctcctcccg gtcgtcggcc gggtggtcgt agcgcccgga gggggctgcc
    22201 tgccagatct ccaccagccc gtcggtaacc ggctcccccg cgccgtcgta gagggtgccc
    22261 tctatcctta tggcccgcgg gtgatccggg gggacgaggt gcgtccagtc ctcgcgcaga
    22321 agccccaggc tcaggtaggg gccgacggtc tgcgaggggg tgagccggag ctcctctctc
    22381 tggcgcccca tcacgcgtgc ggcctctcga agggggtagc gtcccggccc tcgagcacga
    22441 tatcgaagcg gaagcccagg gcctcctccg ggatggtggc ctccaggtcg aacgaggaga
    22501 tcatgcgccg gcgggccttc tcgtcgcgca ccgactggaa gatggggtcc tggaagaaga
    22561 gcgggtcgcc ggggaagtac atctgggtca ccagccggct cctgaacgcc ctcccgaaga
    22621 gggagaagtg gatgtgcgcc gggcgccagg cgttgtagtg gttctgccag gggtaggccc
    22681 cgggctttat ggtgacgaag cggtagtagc cgtcatcgtc ggtgagcgtc ctgcccgccc
    22741 cgctgaagtt ggggtctatg ggggcggggt gctggtcgac cttgtgccgg tagcgcccgg
    22801 cagcgttggc ctgccagatc tcgacgaggg tgttcctgac cgggcgcccg tcgccgtcca
    22861 ggaccctgcc gtgcacgatg atcttctgcc cctgcggctc gccctcgtgc tggcgggtga
    22921 ggtcgttgtc gagctcgccc ggcctgtggt gcccgtagat tgggcccgtg atgtccgaga
    22981 gggtcttggg caggatgatc aggggttctt tgggcgccct caggcgcgtc ccgacgtagt
    23041 cggggtagag gtagggcggc tgctccagct cgtcctcctg cgggacgagg atccctcgcc
    23101 gctcctgcgc gggttcgtgc tgcac
//
