LOCUS       NC_014391.1            25221 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_014391.1 Micromonospora aurantiaca ATCC 27029, complete sequence.
ACCESSION   NC_014391
VERSION     NC_014391.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:56:55
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 6828282
            Orig. end    :: 6853503
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25221
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[6838282:6843503]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15221
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..25221
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..25221
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="19"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03882))"
                     /tool="antismash"
     CDS             1060..1986
                     /locus_tag="ctg1_6119"
                     /transl_table=11
                     /translation="MSEHTPHPHHPAGHTEPADSTLIDLVAGDPPVPITVWRTARTDAE
                     THTSLPTRLAYRLVAAYSRPGEAVVDFTTDHALSPVCARGGRQHHRAWFTDSSTLVIGP
                     ATTGLPAATTETGPLTAPGEPDGGDAQEPPELVDWFGDDLTDPDLPGADAAVVRPPDDG
                     PLDAAPSLVVATWPLHEADTTARVRLAWLLAAGARLLRPGGCLVLVVGVPAGTQPTPED
                     FGPLVAAASRAGLGYLQHIVAVEADTEGDQFVYHVADEELLTLAHADPEQWSVAHLRVH
                     ADLMVFTPHPAPAAESRRRRDGGERRA"
     CDS             1979..2983
                     /locus_tag="ctg1_6120"
                     /transl_table=11
                     /translation="VPEHTTTGPSDPNEPDTRSPAASEDYPGRHRDYEGRHRGYDGRHR
                     ADPEGLSVWATAQSTGPVQRRGRYVPESVKHPARMLPAIAAHAIAAYTQPGDLVLDPMC
                     GIGTTLVEAVHAGRDAFGIEYEPQWSNIADANIRHAHDQGASGRASVIRGDATRLMSLV
                     PKALTGQVALVVTSPPYGPTVHGLVRPGEHGVVKYDDRYNDGEDRGNLAYRDLTGLADG
                     FAQILAGCAALLRPGGVVVVTARPWRKRGELVDLPSAVIAAGLRAGLVPIERCVALLAA
                     VRDGQLVARPSFFQLQQVRKARSSGVPMHLIAHEDVLIFAKQAPPQDGTEVVV"
     PFAM_domain     2117..2377
                     /aSDomain="N6_N4_Mtase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01555.20"
                     /description="DNA methylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6120_1071"
                     /evalue="2.10E-12"
                     /label="ctg1_6120"
                     /locus_tag="ctg1_6120"
                     /protein_end="133"
                     /protein_start="46"
                     /score="47.3"
                     /tool="antismash"
                     /translation="DPEGLSVWATAQSTGPVQRRGRYVPESVKHPARMLPAIAAHAIAA
                     YTQPGDLVLDPMCGIGTTLVEAVHAGRDAFGIEYEPQWSNIA"
     CDS             2980..3846
                     /locus_tag="ctg1_6121"
                     /transl_table=11
                     /translation="VSAPTHRYLSLGAGVQSSTLLLLAAHGAIPGFDAAIFADTGWESA
                     AVYRHLDRLTGIARQASIEVVRVSTGDIRADALDPGHRFASMPLFTLGPNGERGMARRQ
                     CTGEYKIKPIKAEVRRRLGYPHPTRVPAGVWVEVAIGISLDEIGRARDSDVAYMRNVHP
                     LLDLGWRRTDCLRFLAEHGLADTPKSSCVGCPFHDDGFWLAMREHSPQEWADAVAFDRA
                     IRNGSARANADGHPLRGQFFLHRQRVPLDEVQLRPRPRPGDAPGCGPWTCPHDEPATAD
                     AGRGEVA"
     CDS             3843..4394
                     /locus_tag="ctg1_6122"
                     /transl_table=11
                     /translation="VSIAHTTAPRIGSVCTGYGGLDMAVELVLGGQLAWYAETDRHAAT
                     VLAHHWPDVDNLGDIRTVDWTQVAPVDIVTAGFPCQDISNAGKRVGITGEHSSVWNHVA
                     AAVRVLRPRLLFVENVAALLRRGLDVVHADLAAIGYDTSWLCLRASDVGAAHRRDRLFL
                     LATPAEPVGGGSDVADTVRP"
     PFAM_domain     3876..4340
                     /aSDomain="DNA_methylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00145.19"
                     /description="C-5 cytosine-specific DNA methylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6122_1072"
                     /evalue="3.90E-31"
                     /label="ctg1_6122"
                     /locus_tag="ctg1_6122"
                     /protein_end="166"
                     /protein_start="11"
                     /score="108.7"
                     /tool="antismash"
                     /translation="GSVCTGYGGLDMAVELVLGGQLAWYAETDRHAATVLAHHWPDVDN
                     LGDIRTVDWTQVAPVDIVTAGFPCQDISNAGKRVGITGEHSSVWNHVAAAVRVLRPRLL
                     FVENVAALLRRGLDVVHADLAAIGYDTSWLCLRASDVGAAHRRDRLFLLAT"
     CDS             4372..5244
                     /locus_tag="ctg1_6123"
                     /transl_table=11
                     /translation="LPTPCARDGKGPGHPYGLPDLVEPTGTRHSLLPTPTAVAHGSNMS
                     PSAGAARRPSLAGIASRLLPTPTVADSRSSAIATAGRTTPTGRAGRAPSDAARLLPTPR
                     ASDTGTPGRRAGVGWRPPLSQVLLPTPRATDGTKGCPGQRGSHGDLTLPSAAVQVPVRT
                     LPTPRASDAHGPGKHGDGGADLRTTVAGLGQPDADRWGVYAAAVARWELQLGRPVPEPT
                     QPGRHGKPVLAPPFVEWLMGLDEHWVTDPTLGLPRTAALRVLGNGVVPQQAAAALRLLL
                     CPRRWEVRA"
     CDS             complement(5271..6596)
                     /locus_tag="ctg1_6124"
                     /transl_table=11
                     /translation="VSHVRAALYLDFDNVFSGLYKLDPDVAVHFAEDPAGWLRRLATTA
                     TTDGARRWLVLRCYLNPAGWVYRPDPGGEQTRLYFSKFRPSFVRAGFDVIDCPRYSSTK
                     NAADIRIVVDAVDALSADTRYDEFVIASGDSDMTPLLQRLRRSDRRTMIVSPADAAEAF
                     TAIADQVLDSQQLLALVQGESVDLDDEPDSEVEEGFDEHVAAVDGDIPASGQSEAYEAF
                     RSIVTQEYTAATEPLNMASLASRLRTQLGPSVSDSNWFGFGSFARAVASLTLPDLRMSQ
                     HLLWDTSRHPAPKAVTATPPRVALPDPVERLGDQLDLPRMPQPWWPAIYRTLAEYAQSQ
                     RFNWTQCTSWARDHLREQGLPVSRNAVGFVVRGTSFGGCPLHRQPPPTADEIAVAFVGN
                     VLSRADAAEITFSDDEVATVHAWLGAPSANSTEQVGRTENPS"
     PFAM_domain     complement(6078..6584)
                     /aSDomain="NYN"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01936.20"
                     /description="NYN domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6124_1073"
                     /evalue="9.10E-18"
                     /label="ctg1_6124"
                     /locus_tag="ctg1_6124"
                     /protein_end="173"
                     /protein_start="4"
                     /score="65.2"
                     /tool="antismash"
                     /translation="RAALYLDFDNVFSGLYKLDPDVAVHFAEDPAGWLRRLATTATTDG
                     ARRWLVLRCYLNPAGWVYRPDPGGEQTRLYFSKFRPSFVRAGFDVIDCPRYSSTKNAAD
                     IRIVVDAVDALSADTRYDEFVIASGDSDMTPLLQRLRRSDRRTMIVSPADAAEAFTAIA
                     DQVLDS"
     CDS             6754..7116
                     /locus_tag="ctg1_6125"
                     /transl_table=11
                     /translation="VTSHDIGPPEAPSTPASGGGVWTEERIRALGAITDLPTAGRVFGL
                     GRALSYDLARTGEFPAPVLRVGARYKVPVAGILTALGLPPSPGDLTPSGMRSVDHHDEI
                     SSIDPPHTGGDGKKEP"
     CDS             7113..8588
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 212.6; E-value: 1.6e-64)"
                     /gene_kind="other"
                     /locus_tag="ctg1_6126"
                     /transl_table=11
                     /translation="VTRARNPEGALTKRCTCTDPDTGKRLGSQCPKLRRPGGGWHPTHG
                     AWGYQLELPVRPTQPRRQLRRSGFDSRDTATAELRHARALLDLAGGEADLAIEVGDLLH
                     ACRPGTPLPDRDAVAARIRAGVPASVPTTTGEYLTAWLEGRRGLAEKTVRGYSDHIRLY
                     LVPHLGKIPIQSLRTAHIEAMFTAIGRQQDAIRAARASTDPDVRARVKGVRPMEASSIQ
                     RLYATLRKALNDAVVRAKLIPTNPALGVELPTAKRPKARVWTVKAVEHWHATGKRPSPV
                     MVWMPAQAGRFLDYTERHDIVLYAMFLLILHRGLRRGEACGLRDHDVDLDAGYLTVVEQ
                     ITTVGYTPITRPVKSDAGDRMVPLGPKTIAVLRTYLDMRRRWKSVSGDDWPDTGLFFVR
                     PDGKPWHPQTISDRFDHLVAKAKLPPVRLHDLRHCAATYLRHGGADMKEVQETLGHSTI
                     GLTSDTYTSVILELERGSADAVADLIPRDDTAA"
     PFAM_domain     7515..7658
                     /aSDomain="Phage_int_SAM_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14659.8"
                     /description="Phage integrase, N-terminal SAM-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6126_1074"
                     /evalue="7.30E-06"
                     /label="ctg1_6126"
                     /locus_tag="ctg1_6126"
                     /protein_end="182"
                     /protein_start="134"
                     /score="26.2"
                     /tool="antismash"
                     /translation="GEYLTAWLEGRRGLAEKTVRGYSDHIRLYLVPHLGKIPIQSLRTA
                     HIE"
     PFAM_domain     7971..8516
                     /aSDomain="Phage_integrase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00589.24"
                     /description="Phage integrase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6126_1075"
                     /evalue="1.30E-24"
                     /label="ctg1_6126"
                     /locus_tag="ctg1_6126"
                     /protein_end="468"
                     /protein_start="286"
                     /score="87.0"
                     /tool="antismash"
                     /translation="AQAGRFLDYTERHDIVLYAMFLLILHRGLRRGEACGLRDHDVDLD
                     AGYLTVVEQITTVGYTPITRPVKSDAGDRMVPLGPKTIAVLRTYLDMRRRWKSVSGDDW
                     PDTGLFFVRPDGKPWHPQTISDRFDHLVAKAKLPPVRLHDLRHCAATYLRHGGADMKEV
                     QETLGHSTIGLTSDTYTSV"
     CDS             complement(8843..9997)
                     /locus_tag="ctg1_6127"
                     /transl_table=11
                     /translation="MYHASVAAALRYFPLLGRPRPDCPALPLRIKEIADAADTAVQKRE
                     HGMPDAAHALNKAALIASDAGMPDLARKLCWQHINAYRRTARPLSILEARYMLEPVLNL
                     ARLQIRADHGVPALRLLEAMYDAVTHRTALILDKHALPTATLDGDAGERRKLREWVWLQ
                     LLGEGIRILALSNRWAGAAEHARKHNGIGGHLMEGRQAAVIAACIQGKPDQGRKILGSS
                     TLTQLWEHQVATCLNVICIGPADANATHHLTVATEQLAAPISAPNYASYRTRLGLATAI
                     LATPTRPKLAAEILYQTAQQAIDIADGYAARDVLSFCGPIGGTTPDQCADLRRITVGAG
                     LAPGGLPETAVQEISRSAALAEAVVAKALHRADSGRASPENHQR"
     CDS             complement(10001..10960)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_6128"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.2e-30, bitscore:
                     104.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDRLTVSPHRMAALVEAVLAGTPMATAAAGADVDVDDLDAAVQ
                     TYRTAGLTALQRRHDDTWQQALIRPIDWNTAEAVFRSSLAPHLDRLGGGQAGWWFLRKH
                     PYWRFRIRAAHHGAVRALLDDLTADGVTAGWKPGIYEPETAAFGGDTSTAIVHELFCAD
                     SRAVLNYTRHHAPLIGRRELSVLLIRTLQHHAGLDWYEAADMFDQVAQMRPVPAAADAT
                     RIDRLAAQMRPLLALPANARTAMFTPGGPLSDASGWQAAFAAAGQQLADATHAGRLRRG
                     IRAVLAQIVIFHWNRLDLPAHAQGILAHAATAAILPRS"
     PFAM_domain     complement(10019..10738)
                     /aSDomain="Lant_dehydr_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14028.8"
                     /description="Lantibiotic biosynthesis dehydratase C-term"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6128_1076"
                     /evalue="1.80E-35"
                     /label="ctg1_6128"
                     /locus_tag="ctg1_6128"
                     /protein_end="314"
                     /protein_start="74"
                     /score="123.2"
                     /tool="antismash"
                     /translation="TAEAVFRSSLAPHLDRLGGGQAGWWFLRKHPYWRFRIRAAHHGAV
                     RALLDDLTADGVTAGWKPGIYEPETAAFGGDTSTAIVHELFCADSRAVLNYTRHHAPLI
                     GRRELSVLLIRTLQHHAGLDWYEAADMFDQVAQMRPVPAAADATRIDRLAAQMRPLLAL
                     PANARTAMFTPGGPLSDASGWQAAFAAAGQQLADATHAGRLRRGIRAVLAQIVIFHWNR
                     LDLPAHAQGILAHAATAA"
     aSDomain        complement(10019..10747)
                     /aSDomain="TIGR03891"
                     /aSTool="tigrfam"
                     /description="thiopep_ocin: thiopeptide-type bacteriocin
                     biosynthesis domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_6128_0103"
                     /evalue="2.30E-48"
                     /identifier="TIGR03891"
                     /label="ctg1_6128"
                     /locus_tag="ctg1_6128"
                     /protein_end="314"
                     /protein_start="71"
                     /score="163.3"
                     /tool="antismash"
                     /translation="DWNTAEAVFRSSLAPHLDRLGGGQAGWWFLRKHPYWRFRIRAAHH
                     GAVRALLDDLTADGVTAGWKPGIYEPETAAFGGDTSTAIVHELFCADSRAVLNYTRHHA
                     PLIGRRELSVLLIRTLQHHAGLDWYEAADMFDQVAQMRPVPAAADATRIDRLAAQMRPL
                     LALPANARTAMFTPGGPLSDASGWQAAFAAAGQQLADATHAGRLRRGIRAVLAQIVIFH
                     WNRLDLPAHAQGILAHAATAA"
     CDS             complement(10942..12111)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     363.6; E-value: 2e-110)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_6129"
                     /sec_met_domain="LANC_like (E-value: 4.1e-38, bitscore:
                     129.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAATEQPVTAADEADGQSLATGGVGVALLAIERALTGTGDWTAA
                     RHLVAQATGDRVDAGRHAGLYYGAPAILFMLNAATADGRDRYTAARQHLTPHVRRLVRD
                     RLTDADNRLRHGQPATFNEYDLFYGLTGLGALLLRDLPDSDELGDSLTYVVGLTEPRTD
                     DGQQLPGWWVDHDPDPLMPTPGGHANFGMAHGAAGLLALLALATRNGRQVKGQEEAIER
                     LCAWFDQWQQDTTHGPWWPQWLTRDELRAGRFKQEVPGRPSWCYGAPGIARALQLAAIA
                     TNQPDRQVAAETALAASMTGPQLDRLTELGICHGLAGLYATAHRAVRDARTADIAAQLP
                     TLAERLNQRGPSPDHPGLLTGQSGWSLALEAARTSTPPRTRWDTCLLIA"
     PFAM_domain     complement(10951..12066)
                     /aSDomain="LANC_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05147.15"
                     /description="Lanthionine synthetase C-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6129_1077"
                     /evalue="4.80E-36"
                     /label="ctg1_6129"
                     /locus_tag="ctg1_6129"
                     /protein_end="387"
                     /protein_start="15"
                     /score="124.2"
                     /tool="antismash"
                     /translation="DGQSLATGGVGVALLAIERALTGTGDWTAARHLVAQATGDRVDAG
                     RHAGLYYGAPAILFMLNAATADGRDRYTAARQHLTPHVRRLVRDRLTDADNRLRHGQPA
                     TFNEYDLFYGLTGLGALLLRDLPDSDELGDSLTYVVGLTEPRTDDGQQLPGWWVDHDPD
                     PLMPTPGGHANFGMAHGAAGLLALLALATRNGRQVKGQEEAIERLCAWFDQWQQDTTHG
                     PWWPQWLTRDELRAGRFKQEVPGRPSWCYGAPGIARALQLAAIATNQPDRQVAAETALA
                     ASMTGPQLDRLTELGICHGLAGLYATAHRAVRDARTADIAAQLPTLAERLNQRGPSPDH
                     PGLLTGQSGWSLALEAARTSTPPRTRWDTCLL"
     CDS             complement(12108..15221)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     963.6; E-value: 1.7e-291)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_6130"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.9e-197,
                     bitscore: 655.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.2e-18,
                     bitscore: 64.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPQRTFEPVGPALVRASTDPGNLGPEPGPDLIGPAASTEAGLAW
                     LAGQWSRPDVRDAISIASPHLARRVDQLLAADASGTTAAAVRRAVLATCGYLLRWQRRT
                     TPFGLFAAVTTATVGPASATFGDKHRAVARVDGEWLTCVVDRLEAHHALRRRLFVVADS
                     AAVVRDGRVIVAAWPPVGQRTPGMLRETSTRNTAAVRLALQVAAWPIRFDRLLAQIMHE
                     VPHVAVATVEAMLHGLIDGGFLITNLRPPMTAVDGLTHVIDALHSAEAAELPQVTASLD
                     QLCAIRQELARHDAQVDGSEAMLIRAAVTEPMTVLAPNAEHQLAIDVRLDAQISLPPPV
                     LAEAALAVDLLLRLSTQPFGSVAWLDYHARFRDRYGPGALVPVRDLLADSGLGYPTGYL
                     GAPRARPAWRVITERDTHLQALIQQAILDNTGEIHLTDADIEALTVGDHHTAVRPPRVE
                     LAFAVHATAADAIDRGEFTVQVTGAPRTPSSMAGRFSYLLEPTEQEQVTASFSTRGRDA
                     DEELAVQVSFPPRLPRNQNVTRVGRILPFVLPLSEQPDWPDISLDDVAVTADSEQMYLV
                     HQPTGRRIVPHIPHALDTIVQTPPLARFLAEVADARSIAFGPLDHGAAARNLPYIPRIR
                     YRRVILAPARWLLNAADIPPHTPPGAGDTEGRWDAALTEWRRRWRVPARVVACQNELQL
                     PLDLDSPLDRALLRARLGGAERLELREDAPADGYGWTGGHPAEFLSAMTPTAPPARRLP
                     VTAPPGDTLRPGTSTFIHTQIAGNPARFDELLTTHLPRLADRLAGLGLQRWWIRRDRDT
                     IRVEADQRLSLFLRLNEPAAHAAACAILAEFAADLARRALPAQLIFAPYHQHPARYGHG
                     PAQHAAEEVFAADTTAAIAQLRTAEQTDIPAQALAAASMARLAAAFAPDPDTGYGALLA
                     CLQQAAAPAERTITDLARRLADPTTDYRSVRALPGGDAIADAWRARDHALSAYYERLLP
                     QRDPTTVLRTLLHEHHVRAVGVDPDFERATNHAARAAAMRCLAAADTR"
     PFAM_domain     complement(12141..12887)
                     /aSDomain="Lant_dehydr_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14028.8"
                     /description="Lantibiotic biosynthesis dehydratase C-term"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6130_1079"
                     /evalue="5.60E-07"
                     /label="ctg1_6130"
                     /locus_tag="ctg1_6130"
                     /protein_end="1027"
                     /protein_start="778"
                     /score="29.7"
                     /tool="antismash"
                     /translation="ARFDELLTTHLPRLADRLAGLGLQRWWIRRDRDTIRVEADQRLSL
                     FLRLNEPAAHAAACAILAEFAADLARRALPAQLIFAPYHQHPARYGHGPAQHAAEEVFA
                     ADTTAAIAQLRTAEQTDIPAQALAAASMARLAAAFAPDPDTGYGALLACLQQAAAPAER
                     TITDLARRLADPTTDYRSVRALPGGDAIADAWRARDHALSAYYERLLPQRDPTTVLRTL
                     LHEHHVRAVGVDPDFERATNHAARAAA"
     aSDomain        complement(12144..12908)
                     /aSDomain="TIGR03891"
                     /aSTool="tigrfam"
                     /description="thiopep_ocin: thiopeptide-type bacteriocin
                     biosynthesis domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_6130_0104"
                     /evalue="4.10E-28"
                     /identifier="TIGR03891"
                     /label="ctg1_6130"
                     /locus_tag="ctg1_6130"
                     /protein_end="1026"
                     /protein_start="771"
                     /score="97.0"
                     /tool="antismash"
                     /translation="TQIAGNPARFDELLTTHLPRLADRLAGLGLQRWWIRRDRDTIRVE
                     ADQRLSLFLRLNEPAAHAAACAILAEFAADLARRALPAQLIFAPYHQHPARYGHGPAQH
                     AAEEVFAADTTAAIAQLRTAEQTDIPAQALAAASMARLAAAFAPDPDTGYGALLACLQQ
                     AAAPAERTITDLARRLADPTTDYRSVRALPGGDAIADAWRARDHALSAYYERLLPQRDP
                     TTVLRTLLHEHHVRAVGVDPDFERATNHAARAA"
     PFAM_domain     complement(13101..15068)
                     /aSDomain="Lant_dehydr_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04738.15"
                     /description="Lantibiotic dehydratase, N terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6130_1078"
                     /evalue="1.20E-201"
                     /label="ctg1_6130"
                     /locus_tag="ctg1_6130"
                     /protein_end="707"
                     /protein_start="51"
                     /score="671.2"
                     /tool="antismash"
                     /translation="RPDVRDAISIASPHLARRVDQLLAADASGTTAAAVRRAVLATCGY
                     LLRWQRRTTPFGLFAAVTTATVGPASATFGDKHRAVARVDGEWLTCVVDRLEAHHALRR
                     RLFVVADSAAVVRDGRVIVAAWPPVGQRTPGMLRETSTRNTAAVRLALQVAAWPIRFDR
                     LLAQIMHEVPHVAVATVEAMLHGLIDGGFLITNLRPPMTAVDGLTHVIDALHSAEAAEL
                     PQVTASLDQLCAIRQELARHDAQVDGSEAMLIRAAVTEPMTVLAPNAEHQLAIDVRLDA
                     QISLPPPVLAEAALAVDLLLRLSTQPFGSVAWLDYHARFRDRYGPGALVPVRDLLADSG
                     LGYPTGYLGAPRARPAWRVITERDTHLQALIQQAILDNTGEIHLTDADIEALTVGDHHT
                     AVRPPRVELAFAVHATAADAIDRGEFTVQVTGAPRTPSSMAGRFSYLLEPTEQEQVTAS
                     FSTRGRDADEELAVQVSFPPRLPRNQNVTRVGRILPFVLPLSEQPDWPDISLDDVAVTA
                     DSEQMYLVHQPTGRRIVPHIPHALDTIVQTPPLARFLAEVADARSIAFGPLDHGAAARN
                     LPYIPRIRYRRVILAPARWLLNAADIPPHTPPGAGDTEGRWDAALTEWRRRWRVPARVV
                     ACQNELQLPLDLDSPLDRALL"
     CDS             complement(15315..15515)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_6131"
                     /sec_met_domain="LD_lanti_pre (E-value: 9.6e-14, bitscore:
                     49.6, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMAPPTAVLDAPPIDAEVVTDDDFVLDMRVIEATTPLVIMACST
                     SDGCGSTCNTSACATSSYDPA"
     CDS_motif       complement(15402..15515)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSMAPPTAVLDAPPIDAEVVTDDDFVLDMRVIEATTPL"
                     /locus_tag="ctg1_6131_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15315..15401)
                     /prepeptide="core"
                     /locus_tag="ctg1_6131_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-13.80"
                     /molecular_weight="2523.7"
                     /monoisotopic_mass="2522.0"
                     /core_sequence="VIMACSTSDGCGSTCNTSACATSSYDPA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSMAPPTAVLDAPPIDAEVVTDDDFVLDMRVIEATTPL"
                     /leader_location="[15401:15515](-)"
                     /alternative_weights="2541.8"
                     /alternative_weights="2559.8"
                     /alternative_weights="2577.8"
                     /alternative_weights="2595.8"
                     /alternative_weights="2613.8"
                     /alternative_weights="2631.9"
     aSDomain        complement(15336..15449)
                     /aSDomain="TIGR04363"
                     /aSTool="tigrfam"
                     /description="LD_lanti_pre: FxLD family lantipeptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_6131_0105"
                     /evalue="6.80E-14"
                     /identifier="TIGR04363"
                     /label="ctg1_6131"
                     /locus_tag="ctg1_6131"
                     /protein_end="60"
                     /protein_start="22"
                     /score="49.6"
                     /tool="antismash"
                     /translation="DDFVLDMRVIEATTPLVIMACSTSDGCGSTCNTSACAT"
     CDS             complement(15558..16787)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_6132"
                     /sec_met_domain="PCMT (E-value: 3.2e-36, bitscore: 123.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSQTADTGFAADRAAELRAALVGDLRAQGKITSEVVEAAVRRVPR
                     ERFMPSDTDLDVAYGFDNSVVTKRDEHGVAISSVSAAYIQARMLEQADLAAGMTVLEVG
                     SGGLNAAYLAEIVGPQGRVVSVDIDPEVTDRAATLLEENGYGSRVRVLVADAEHGVPGE
                     GPFDAIIVTVGAWDIAPALLDQLREGGVIVLPLIMNAVTRTIGFRRDGDHLISASVEVA
                     GFVPMQGAGARPDRVFLLPDANGRHVRLLFDSDVPDRLDRLDGVLAMERTELWSGVTIG
                     NGVSFADLHLWFAWFLPGFCRVAADEGTDLAAERRWFPFGVVHGAGFAYLAVRPATEGE
                     GFEFGARAFGPDGERAAAAMVEQIRAWDRDGRHVEPRFGYWPSDSDHTRIPADAAVMDK
                     THGVISISWS"
     aSDomain        complement(15564..16748)
                     /aSDomain="TIGR04364"
                     /aSTool="tigrfam"
                     /description="methyltran_FxLD: methyltransferase, FxLD
                     system"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_6132_0106"
                     /evalue="2.60E-147"
                     /identifier="TIGR04364"
                     /label="ctg1_6132"
                     /locus_tag="ctg1_6132"
                     /protein_end="408"
                     /protein_start="13"
                     /score="489.0"
                     /tool="antismash"
                     /translation="AAELRAALVGDLRAQGKITSEVVEAAVRRVPRERFMPSDTDLDVA
                     YGFDNSVVTKRDEHGVAISSVSAAYIQARMLEQADLAAGMTVLEVGSGGLNAAYLAEIV
                     GPQGRVVSVDIDPEVTDRAATLLEENGYGSRVRVLVADAEHGVPGEGPFDAIIVTVGAW
                     DIAPALLDQLREGGVIVLPLIMNAVTRTIGFRRDGDHLISASVEVAGFVPMQGAGARPD
                     RVFLLPDANGRHVRLLFDSDVPDRLDRLDGVLAMERTELWSGVTIGNGVSFADLHLWFA
                     WFLPGFCRVAADEGTDLAAERRWFPFGVVHGAGFAYLAVRPATEGEGFEFGARAFGPDG
                     ERAAAAMVEQIRAWDRDGRHVEPRFGYWPSDSDHTRIPADAAVMDKTHGVISISW"
     PFAM_domain     complement(16104..16733)
                     /aSDomain="PCMT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01135.21"
                     /description="Protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase (PCMT)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6132_1080"
                     /evalue="9.80E-36"
                     /label="ctg1_6132"
                     /locus_tag="ctg1_6132"
                     /protein_end="228"
                     /protein_start="18"
                     /score="123.6"
                     /tool="antismash"
                     /translation="AALVGDLRAQGKITSEVVEAAVRRVPRERFMPSDTDLDVAYGFDN
                     SVVTKRDEHGVAISSVSAAYIQARMLEQADLAAGMTVLEVGSGGLNAAYLAEIVGPQGR
                     VVSVDIDPEVTDRAATLLEENGYGSRVRVLVADAEHGVPGEGPFDAIIVTVGAWDIAPA
                     LLDQLREGGVIVLPLIMNAVTRTIGFRRDGDHLISASVEVAGFVPMQ"
     CDS             complement(17138..17908)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 56.8; E-value:
                     3.7e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_6133"
                     /sec_met_domain="PCMT (E-value: 5.9e-08, bitscore: 31.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTHNGRLRPPQLLELLDPTIRHELDRLEIRPGHRILEIGAGTG
                     EITALLARLVGPSGRVTAVDKDTSYLAPTAVIDVYQRNLDGDELPGEADTFDLAVARWL
                     HGALPDSNAVIRQMIDRLRPDGWLILADLPFTPSRVFRRPHREDADLIQHLVTRIYGLV
                     TDPGGRATWPNDVPELLVANGMKTVCTHRSIETWAGGGPGCRILADAAEHLRPLLIQPE
                     LSHADLGRFIDLMADPGVLLGSYERRAVHAHKGT"
     PFAM_domain     complement(17519..17797)
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08241.14"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6133_1081"
                     /evalue="6.30E-08"
                     /label="ctg1_6133"
                     /locus_tag="ctg1_6133"
                     /protein_end="130"
                     /protein_start="37"
                     /score="33.2"
                     /tool="antismash"
                     /translation="LEIGAGTGEITALLARLVGPSGRVTAVDKDTSYLAPTAVIDVYQR
                     NLDGDELPGEADTFDLAVARWLHGALPDSNAVIRQMIDRLRPDGWLIL"
     CDS             complement(17905..18750)
                     /locus_tag="ctg1_6134"
                     /transl_table=11
                     /translation="MPKGYLVGITRTPPPTRLRSGQPARPVLLDLAARITPDTCDAVEG
                     TYDVVYHRAWFNSGGEPSMRDVVRWYADDNSGAELAQRYPPLTRHPNLRRDFWPSGWLH
                     DKNLFRAYHSTDWLLAQAHLQTSRRSENAALMDGLATLNTWHNPGPLRRGLTAWVLADT
                     AGLTAHPDTLDHAGRSGIGIRTISGDGRERYLLILHPSTGAVLAYEHARLTSAGWRTRS
                     YLLLLTRTYSPGRWWEPPPVDPTAPPPPPLDRREMPRASPVVLTLAYTPCESDRQGASG
                     "
     CDS             complement(19016..20146)
                     /locus_tag="ctg1_6135"
                     /transl_table=11
                     /translation="MTTGYVFHPEYLWHDTGTSAGLLPANPAAGIPPAAHIENPEAKRR
                     VHELIHASGLLGELMSIEPRRATVAELLRVHTEAHVQHIKAQSDLRAGGDAGDGFSPVG
                     HGSYDIARLAAGGLIELVTAAVHGDITNGYALLRPPGHHATAEAGMGFCLFNSIAVAAR
                     HAQAELGLARIAVVDFDAHHGNGTQSIFYDDPSVLTISLHQAGCFPPDSGWTHENGTGY
                     GTGYALNVPLPPGSGHAAYLSAMHQVVLPVLDRFAPDLILLAAGFDANVWDPLARQMLT
                     AASYREMTRLLIDAADRLCHGRLIAAHEGGYNPWYVPYCALAFLEELAGTTTHVTDPLA
                     AVVAGYAAEPLTPQQQAAISEAAQLVSRLGTPVTAS"
     PFAM_domain     complement(19166..20041)
                     /aSDomain="Hist_deacetyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00850.21"
                     /description="Histone deacetylase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6135_1082"
                     /evalue="2.80E-83"
                     /label="ctg1_6135"
                     /locus_tag="ctg1_6135"
                     /protein_end="327"
                     /protein_start="35"
                     /score="279.9"
                     /tool="antismash"
                     /translation="HIENPEAKRRVHELIHASGLLGELMSIEPRRATVAELLRVHTEAH
                     VQHIKAQSDLRAGGDAGDGFSPVGHGSYDIARLAAGGLIELVTAAVHGDITNGYALLRP
                     PGHHATAEAGMGFCLFNSIAVAARHAQAELGLARIAVVDFDAHHGNGTQSIFYDDPSVL
                     TISLHQAGCFPPDSGWTHENGTGYGTGYALNVPLPPGSGHAAYLSAMHQVVLPVLDRFA
                     PDLILLAAGFDANVWDPLARQMLTAASYREMTRLLIDAADRLCHGRLIAAHEGGYNPWY
                     VPYCALAFLEE"
     CDS             complement(20193..21398)
                     /NRPS_PKS="Domain: Aminotran_5 (84-259). E-value: 3e-10.
                     Score: 31.4. Matches aSDomain:
                     nrpspksdomains_ctg1_6136_Aminotran_5.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 293.2;
                     E-value: 5.3e-89)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_6136"
                     /transl_table=11
                     /translation="VTHTLNLPDAADLSRAQIDITAVLDHLVREADAAAATSIGFPGAV
                     DLDHTEVMTRLGGRLWNNIGDPTDTGGVAHTRALERAVITWVADLLAMPADDRWGYVSS
                     GGTEGNLSALHAAHRRDPTARIYYSTAAHYSVPKVVRLLGARGVSVHAQPDGEMDYTHL
                     AAQLRRRRRWPAIVVATAGTTMTEAVDDTGRIRAVLDEHHAGGHLHVDAALSGIPLALD
                     GRLRLDDASGISSIAVSGHKFFGVPTPCGIVLIRDHLRIHGSRVAYTAMADTTITGSRC
                     GLAAALLWHAIATHGREGHRWRATAARRLAAYTTDRLNAAGWPAWRHPHAFTVVLPTPP
                     GQVRRKWLLATDGDTSHLICMPGITRGQIDAFVADLAAAPAPPPIPRPRPATPTPTSVP
                     AH"
     PFAM_domain     complement(20439..21167)
                     /aSDomain="Pyridoxal_deC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00282.21"
                     /description="Pyridoxal-dependent decarboxylase conserved
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6136_1083"
                     /evalue="1.10E-20"
                     /label="ctg1_6136"
                     /locus_tag="ctg1_6136"
                     /protein_end="320"
                     /protein_start="77"
                     /score="73.9"
                     /tool="antismash"
                     /translation="ALERAVITWVADLLAMPADDRWGYVSSGGTEGNLSALHAAHRRDP
                     TARIYYSTAAHYSVPKVVRLLGARGVSVHAQPDGEMDYTHLAAQLRRRRRWPAIVVATA
                     GTTMTEAVDDTGRIRAVLDEHHAGGHLHVDAALSGIPLALDGRLRLDDASGISSIAVSG
                     HKFFGVPTPCGIVLIRDHLRIHGSRVAYTAMADTTITGSRCGLAAALLWHAIATHGREG
                     HRWRATAARRLAAYTTDRLNA"
     aSDomain        complement(20622..21146)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_6136_Aminotran_5.1"
                     /evalue="3.00E-10"
                     /label="ctg1_6136_Aminotran_5.1"
                     /locus_tag="ctg1_6136"
                     /protein_end="259"
                     /protein_start="84"
                     /score="31.4"
                     /tool="antismash"
                     /translation="TWVADLLAMPADDRWGYVSSGGTEGNLSALHAAHRRDPTARIYYS
                     TAAHYSVPKVVRLLGARGVSVHAQPDGEMDYTHLAAQLRRRRRWPAIVVATAGTTMTEA
                     VDDTGRIRAVLDEHHAGGHLHVDAALSGIPLALDGRLRLDDASGISSIAVSGHKFFGVP
                     TPCGIVLIRDHL"
     CDS             complement(21395..22243)
                     /locus_tag="ctg1_6137"
                     /transl_table=11
                     /translation="MPADYSRTPETMLPPPPSAQPMHPTVSAPPYEHVPVDDRVPPEVR
                     RWADLRKQVAYRCKRINTGHMVEADQRFGGREALGPHGVVLFFVSDAPGEPHGYRLHTA
                     YRLWLASPDADDLPRLLADLDGVARDNITRAASARRRWHPLGPEGSMVNGGDMSLPEHA
                     TYVGAGVSTLDSDQGRWYQLAHTLRDLPATGHRLSVFDLKGQAYVLLTDGTALHIDRDP
                     HACLGVDGIRCNRTLDPDRVTYYNRHENLTEDGDDATRAVWRHLGALHHTLTAHLHGLP
                     A"
     CDS             complement(22455..23900)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038:phenylalanine-specific permease (Score: 122.2;
                     E-value: 3.3e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_6138"
                     /transl_table=11
                     /translation="MQVALARRTLTPVGLWVFGAAASAPTVVLAGGIVATYATTRVTAL
                     PLVFVLVAAVVALLAVGYTAMARQVGHPAAYYGILANSLGRGWGVAAGLVALVAYNAIQ
                     ISLYGLVGATLAGQLGGAWWVWAGLALAVIGAFGTRAIVLSTRVLVAVLAVSLLIVAAF
                     VLAGVGQPADSGLSWAGFDALGLAVSGVGGAVAFCVAALMGVDAPGSMVEEAVDRRSVG
                     RATIGAVVVLGGVYALAAWAMGVAVGPDAVGEVAANPAAGLPFSILERLGGGWVVLAEL
                     VLILAILTSKLVFHNVVARYVFALAREGVLPAALARTGSTARVSAPRGGSLTQTAIASV
                     VVGAFALAGAEPIAVMFTWLSTLGAMGLLCLLLAASVAAMVAPASVRGPQAGAWEWRLA
                     PALGVLGGLVLLGLMVGNAGSLLGAAPGSLYPFLLPTILAATAVLGGVWAGHLRQSRPD
                     VYAGIGRGTPSTHAVPDAISVSI"
     PFAM_domain     complement(22746..23843)
                     /aSDomain="AA_permease_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13520.8"
                     /description="Amino acid permease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_6138_1084"
                     /evalue="3.90E-09"
                     /label="ctg1_6138"
                     /locus_tag="ctg1_6138"
                     /protein_end="385"
                     /protein_start="19"
                     /score="36.0"
                     /tool="antismash"
                     /translation="AAASAPTVVLAGGIVATYATTRVTALPLVFVLVAAVVALLAVGYT
                     AMARQVGHPAAYYGILANSLGRGWGVAAGLVALVAYNAIQISLYGLVGATLAGQLGGAW
                     WVWAGLALAVIGAFGTRAIVLSTRVLVAVLAVSLLIVAAFVLAGVGQPADSGLSWAGFD
                     ALGLAVSGVGGAVAFCVAALMGVDAPGSMVEEAVDRRSVGRATIGAVVVLGGVYALAAW
                     AMGVAVGPDAVGEVAANPAAGLPFSILERLGGGWVVLAELVLILAILTSKLVFHNVVAR
                     YVFALAREGVLPAALARTGSTARVSAPRGGSLTQTAIASVVVGAFALAGAEPIAVMFTW
                     LSTLGAMGLLCLLLAASVAAMVAPAS"
     CDS             complement(23912..24292)
                     /locus_tag="ctg1_6139"
                     /transl_table=11
                     /translation="MLSALTRIRALAPPRCNAGRWLPPWPSSARVDAAVTDAGDVTSDE
                     FAWGYAIRREWANGSHDLFGFTPDVETAQRRLDRDRSYWRGGPVRPAAVFLVPANAADV
                     SRHPVDGCRLSCCPDLVERGQR"
     CDS             24439..25194
                     /locus_tag="ctg1_6140"
                     /transl_table=11
                     /translation="MRAHAARQPVGPTVARSRPPHPPQRRTAGLQQHRRPRLIPEPSEH
                     AVSRPGTADLRVRRQPLRVEPAVIAGQQGTCSTALPGTSREMSQVVMRRMRKHRIDVGV
                     QQREPGCVRSEDPLQVVHPPRSRHRRLQPRIPNRYSGVVVGRGNLALVQPARQHKSCVA
                     AQNTGTLTCIRDQPGGRRLGQQRIHHDPRQRLNVLTGRAADRRPRRHHVASLADRLGPL
                     FPSSASATSDSAACATRCRDIRRAESSAR"
ORIGIN
        1 gcgtcggcca cagcgccttc taccagtggt tacgcgccgg ccggcaacgc gccaccgaca
       61 gagaacgcca cgaccacgcc cgggtcgagc tgacccggca ggcctggtcg gagcaccgcg
      121 gcgtctacgg cgcccgccgg ctgaccgcag agctgcacga gcgcggccac cgctggaacc
      181 gcaaagcggt agcgaggctg atgcgcctgg ccggcatcga gggcgcccac cggcgccgac
      241 gcggcaagcc ccgccgcaaa gccgcctcga ccgcgaccgc cccggacctg gtccagcggc
      301 agttcagcac gaccgcaccg aaccggctct gggtcgccga catctcttac ctacgcacct
      361 gggaaggctt cctctacctc gcggtcgtgg tcgacgccta ctcccgccgc gtcgtcgggt
      421 gggcaatggc cgatcacctg cgcaccgagc tgatcctcga cgccgtcggc atggccatcc
      481 agcaccgccg acccgcccgc gagcagctgg ttcaccactc cgaccgcgga acccagtaca
      541 cctcgttcga gttcggccgc accctgcgct cctgcggcgt cctggcctca atgggttcgg
      601 tcgccgactg ctacgacaac gccatggccg agtcgttctt cgccaccctc aagaccgagt
      661 tggtctacac ccgggcctgg ccatcgcggc atgaactgga gatggaggtg ttctcctaca
      721 tcgagggctt ctacaaccct cgccgtcggc acagccgtct gggtaacgtc agccccgaca
      781 cctacgagaa gctccaccaa gagtccctga cagacatcga ggtgtccggc cgataggggt
      841 cacttcagtg gccggcgtga agccgggccc cgtcgcggta gggcggctgc cgacggctcg
      901 tcacgtcgcg agcgaccgac aacgtgacgg aaatcagcac aagctgatgg cgggtcgagc
      961 gttgtgagtg cttgtgggtt cggcaagtgt tcgcaggggc tcacaaaacc cggtttgggg
     1021 gtgtcagcgc ttcacggcgc ggcgcggagc cgacagcaca tgagcgagca cacgccgcac
     1081 ccgcaccacc cggccggcca caccgagccg gccgactcca cactgatcga cctggtcgcc
     1141 ggcgatccgc cggtgccgat cacggtctgg cgcacggccc gtaccgacgc cgaaacccac
     1201 accagcctac ccacccgtct ggcctaccgc ctcgtcgccg cgtacagccg gccgggggag
     1261 gcggtcgtcg acttcaccac cgatcacgcc ctgtccccgg tctgcgcccg aggcgggcgc
     1321 cagcaccacc gcgcctggtt caccgacagc tccaccctgg tcatcggacc cgccaccacc
     1381 ggcctgccgg cggccacgac cgagaccggc ccactcaccg cgcccggcga gccggatggc
     1441 ggcgacgcgc aggagccgcc cgagctggtc gactggttcg gcgacgacct caccgacccc
     1501 gacctgcccg gcgccgacgc cgcggtcgtc cggccgcccg acgacggtcc gctggacgcg
     1561 gcccccagcc tggtggtcgc cacctggccg ctgcacgagg ccgacacgac cgcccgggtc
     1621 cgcctcgcct ggctgctggc cgcaggcgcg cggctactgc gccccggcgg ctgcctcgtc
     1681 ctcgtcgtcg gcgtgcccgc cggcacgcag cccacgccgg aggacttcgg gccgctcgtg
     1741 gccgccgcct cccgggccgg actgggctac ctgcagcaca tcgtcgccgt ggaggccgac
     1801 accgagggcg accagttcgt ctaccacgtc gccgacgagg aactgctcac cctggctcac
     1861 gccgaccccg agcagtggtc ggtcgcccac ctgcgggtgc acgccgacct gatggtcttc
     1921 accccacacc cggctcccgc agccgagtcg cggcggcgcc gcgacggcgg tgagcgccgt
     1981 gcctgagcac accaccaccg gaccatccga cccgaacgag ccggacaccc gcagccccgc
     2041 ggccagcgag gactacccgg gccggcaccg cgactacgaa ggccgccacc gcgggtacga
     2101 cggccgccac cgcgccgacc ccgagggtct gtccgtctgg gccaccgccc agtcgaccgg
     2161 ccccgtccag cgacgcggac gctacgtgcc ggaatcggtc aagcatcccg cccggatgct
     2221 gcccgccatc gccgcccacg ccatcgccgc ctacacccag cccggcgacc tggtcctaga
     2281 cccgatgtgc ggcatcggca ccaccctggt cgaggccgtc cacgccggac gcgacgcctt
     2341 cggcatcgag tacgagccgc aatggtcgaa catcgccgac gccaacatcc gccacgccca
     2401 cgaccagggc gccagcggac gcgcatcggt catccgcggc gacgcgaccc ggctgatgtc
     2461 cctcgttccg aaagctctca ccgggcaggt ggcgctcgtg gtcacctcgc cgccgtatgg
     2521 gccgaccgtc cacggcctcg tccgccccgg cgagcacggg gtcgtcaagt acgacgaccg
     2581 gtacaacgac ggcgaggacc ggggcaacct cgcctaccgc gacctgaccg gcctcgccga
     2641 cggcttcgcc cagatcctgg ccggctgcgc cgccctgctg cgacccggcg gcgtcgtcgt
     2701 ggtcaccgcc aggccgtggc gcaagcgcgg cgagctggtc gacctgccca gcgccgtcat
     2761 cgccgccggg ctgcgcgccg ggctcgtgcc gatcgagcgg tgcgtcgccc tgctagccgc
     2821 ggtccgtgac gggcagctcg tcgcccgccc gtcgttcttc cagctccagc aggtccgcaa
     2881 ggcccgctcg tccggggtgc cgatgcacct catcgcgcac gaggacgtcc tgatcttcgc
     2941 caagcaggcg ccgccgcagg acggaaccga ggtggtcgtg tgagcgcacc cacccaccgc
     3001 tacctgtccc tgggcgccgg cgtgcagagc tccacgctcc tgctgctcgc cgcccacggc
     3061 gcgatccccg ggttcgacgc ggcgatcttc gccgacaccg gctgggagtc ggcagcagtc
     3121 taccggcatc tggaccgcct gaccggcatc gcgcggcagg ccagcatcga ggtcgtgcgc
     3181 gtcagcaccg gtgacatccg ggctgacgcg ctcgacccag gccacaggtt cgcctccatg
     3241 cccctgttca ccctgggacc caacggtgag cggggcatgg cccgccggca gtgcaccggc
     3301 gagtacaaga tcaaaccgat caaggcggag gtgcggcgcc ggctgggcta cccgcacccg
     3361 acgcgagtgc cggccggggt ttgggtggag gtcgcgatcg ggatcagcct cgatgagatc
     3421 ggccgggccc gtgactccga cgtcgcctac atgcgcaacg tgcacccgct gctcgacctg
     3481 ggctggcggc gcaccgactg cctgcgcttc ctggccgagc acggtctcgc cgacaccccg
     3541 aagtcgtcgt gcgtgggctg cccgttccac gacgacggct tctggctcgc catgcgcgag
     3601 cacagcccgc aggagtgggc cgacgcggtc gccttcgacc gcgccatccg caacggctcc
     3661 gcgcgggcca acgccgacgg gcacccgctg cgcgggcagt tcttcctgca ccgccagcgg
     3721 gtgccgctcg acgaggtgca gctgcgccca cgcccccgac caggggatgc gccgggctgt
     3781 gggccgtgga cctgccccca cgacgagccg gcgacagcgg acgccgggcg cggggaggtg
     3841 gcgtgagcat tgcccacacc accgcccccc ggatcggatc ggtctgcacc ggctacggcg
     3901 ggctcgacat ggccgtcgaa ctggtgctcg gcggccagct cgcctggtac gccgagactg
     3961 accggcacgc cgccaccgtc ctcgcccacc actggcccga cgtcgacaac ctcggcgaca
     4021 tccgcaccgt cgactggacg caggtcgcgc ccgtcgacat cgtcaccgca ggatttccct
     4081 gccaggacat cagcaacgcc ggaaaacgcg tcggtatcac cggcgagcac tccagcgtct
     4141 ggaaccacgt cgccgcagcc gttcgcgtcc ttcgaccgcg gctgctcttc gtggagaacg
     4201 tcgctgccct cctgcggcga ggactcgacg tcgtccacgc cgatctggcc gcgatcgggt
     4261 acgacacgag ctggctatgc ctacgcgcat ccgacgtcgg tgccgctcac cgcagggacc
     4321 ggctgttcct gctggccact cccgccgagc cagtgggagg gggttcggac gttgccgaca
     4381 ccgtgcgccc gtgacggcaa gggccccggc cacccgtacg ggctgccgga cctggtcgag
     4441 ccgaccggca cccgtcacag cctgctgccg acgccgaccg cagtggccca cgggtcgaac
     4501 atgtccccct cggcgggggc ggcccgccgg ccgtccctgg ccggcatcgc ctcgcggttg
     4561 ctgccgacgc cgacggtggc cgacagccgg tcctcggcga tcgccaccgc cggacgcacc
     4621 acgcccaccg ggcgcgcggg ccgggcgccg agcgacgcgg cgcggctgct gccgacgccg
     4681 agagccagcg acaccggcac cccgggccga cgggccggcg tcggatggcg accgccgctg
     4741 tcgcaggtac tgctgcccac ccccagggca accgacggca ccaagggctg ccccgggcaa
     4801 cgcgggtcgc acggcgacct caccctgccg tcggcagccg tgcaagttcc ggtccggacg
     4861 ctgcctactc cgcgcgcctc cgacgcacac gggccgggta agcacggtga cggtggcgcg
     4921 gacctgcgca ccaccgtggc cgggctgggc cagcccgacg ccgaccggtg gggggtgtac
     4981 gccgcggcgg tggcccggtg ggagctgcag ctcggacggc ccgtgccgga gccgacccaa
     5041 ccggggcggc acggcaaacc ggtcctggcg ccgccgttcg tggaatggct catgggcctc
     5101 gacgagcact gggtcaccga cccaactctc gggctgccgc gcaccgccgc actacgggtt
     5161 ctcggcaacg gcgtcgtccc ccaacaggct gccgcagcgt tgcggctatt gctgtgcccc
     5221 cgtcggtggg aggtgcgcgc gtgaccagcg gtcgccgcag gtggaacgca ctacgacgga
     5281 ttctccgtcc ggcctacctg ctcggtgctg ttggcagatg gtgcgcccag ccaggcgtgg
     5341 accgtcgcga cctcatcgtc ggagaacgtg atctccgctg cgtcggcgcg gctgagaacg
     5401 ttgccgacga acgctactgc gatctcgtcg gctgtcggtg gaggttggcg gtgcaacggg
     5461 caaccgccga acgacgtgcc ccgcacgacg aacccgacgg cgttgcggct gaccggcagc
     5521 ccctgctcac gaaggtggtc acgagcccag ctggtgcact gggtccagtt gaaccgctga
     5581 gactgggcgt actccgcgag tgtccggtag atcgccggcc accagggttg cggcatccgc
     5641 ggcagatcga gctggtcgcc caggcgctcg acgggatccg gcagggcgac gcgtggtggc
     5701 gtcgcggtga cggccttcgg agccggatgg cggctggtgt cccagagcag gtgctgcgac
     5761 atccgcaggt ccggcaacgt caggctcgcc acggctcggg cgaagctgcc aaagccgaac
     5821 cagttgctgt cgctgaccga cggaccgagc tgcgtccgca gccgggaagc gagcgaagcc
     5881 atgttcaacg gctcggtcgc tgcggtgtac tcctgggtca cgattgaccg gaaggcctcg
     5941 taggcctcgc tctgaccaga ggcaggaatg tcaccgtcga cagcggccac atgttcgtcg
     6001 aacccctcct ccacctcact gtcgggctcg tcgtcgaggt cgaccgactc gccctgcacc
     6061 agtgccagca gttgctggct gtcgagaacc tggtcggcga tcgcggtgaa ggcctcagcc
     6121 gcgtcggccg gtgacacgat catcgttcgc cggtcggagc ggcgcaggcg ttgcagcaga
     6181 ggggtcatgt cggagtcgcc agaggcgatc acgaactcgt cgtaccgggt gtcggcggac
     6241 agcgcgtcga cggcgtcgac gacgatcctg atgtcggccg cgttctttgt gctgctgtag
     6301 cgagggcagt cgatcacgtc gaagccggct cgaacgaacg agggccgaaa cttcgagaag
     6361 tacaaccgcg tctgctcccc gcccgggtct gggcggtaca cccagcctgc gggattgagg
     6421 tagcagcgca ggaccagcca gcgccgcgcg ccatccgtcg tggccgtcgt cgccagcctg
     6481 cgcagccatc ccgccggatc ctcggcgaag tgaactgcca cgtccggatc caacttgtag
     6541 aggccgctga acacgttatc gaagtcgagg tagagcgccg cccgaacgtg actcacgagc
     6601 gcaacctacc aaccctgagc aaggacgcca tcacacgtac tgccccgcgg cagtacgtgt
     6661 ggtggcgcgt gatggtccgc cacaagcgag gcccacacct gtccgacctg actccacttc
     6721 cctctcccct ttcgacgatt cggagtaatc accgtgacca gccacgacat cggtccccca
     6781 gaagcgccca gcacccccgc cagcggtggc ggagtgtgga ccgaagagcg catccgcgca
     6841 ctcggcgcga tcaccgacct gcccaccgcc ggtcgtgtct tcggcctggg acgagccctg
     6901 tcctacgacc tcgcccgcac cggcgaattc ccagcgccgg tcctgcgggt cggcgcccgc
     6961 tacaaggtgc ccgtcgccgg catcctcacc gccctgggcc tgccgccgtc gcccggcgac
     7021 ttgaccccga gcgggatgcg aagcgtcgat caccacgacg aaatcagcag catcgacccg
     7081 ccgcacaccg gcggcgacgg aaagaaggaa ccgtgacccg cgcccgtaac cccgaagggg
     7141 ccctcaccaa gcgctgcacc tgcaccgacc ccgacaccgg caaacggctc ggcagccagt
     7201 gcccgaaact acgccgcccc ggcggcggct ggcaccccac ccacggcgcg tggggctacc
     7261 aactcgaact gcccgtccgg cccacgcagc cgcgccggca actgcgtcgc tccggcttcg
     7321 acagccgcga caccgccacc gccgaactgc gccacgcccg cgcgctactc gacctcgccg
     7381 gcggcgaggc cgacctcgcc atcgaggtcg gggacctgct gcacgcctgc cggcccggca
     7441 cgccgctgcc cgaccgcgac gcggtcgccg cccgcatccg cgccggcgtg cccgcctccg
     7501 ttcccaccac caccggcgaa tacctgaccg cctggctgga aggacgacgc gggttggcgg
     7561 aaaagaccgt gcgcggctac tccgaccaca tccgcctgta cctggtcccc cacctcggca
     7621 agatccccat ccagagcttg cgcaccgccc acatcgaggc catgttcacc gcgatcggtc
     7681 gccagcagga cgccatccgc gccgcccgcg ccagcaccga ccccgacgta cgcgcgcgcg
     7741 tcaaaggcgt ccggccgatg gaagcctcca gcatccagcg gctctacgcc accctgcgca
     7801 aagccctcaa cgatgccgtc gtccgggcca agctgatccc caccaacccc gccctcggcg
     7861 tcgaactacc cacggccaag cgacccaagg cgcgggtgtg gactgtcaag gcggtcgagc
     7921 actggcatgc cacgggcaaa cggccgagcc cggtgatggt gtggatgccc gcacaggccg
     7981 ggcggttcct cgactacacc gaacgacacg acatcgtcct ctacgcgatg ttcctgctca
     8041 tcctgcaccg cggtctgcgc cgcggggagg cgtgcggcct gcgcgaccac gacgtcgacc
     8101 tcgacgccgg ctacctcacc gtcgtcgaac agatcaccac cgtcggctac acacccatca
     8161 cgcgacccgt caagagcgac gccggtgacc gcatggtgcc cctcggcccg aaaaccatcg
     8221 ccgtcctgcg gacctacctc gacatgcgcc gccggtggaa gagtgtcagc ggtgacgact
     8281 ggccagacac cggcctgttc ttcgtccgcc ccgacggcaa gccgtggcac ccacagacca
     8341 tcagcgaccg gtttgaccac ctggttgcca aggcgaagct gccgcccgtg cggctgcacg
     8401 acctacgcca ctgcgccgcc acctacctac gccacggcgg cgccgacatg aaggaggtcc
     8461 aggaaaccct cggccactcc accatcggct tgacctccga cacctacacc agcgtcatcc
     8521 tcgaactcga acgcggaagc gccgacgccg tcgccgacct catcccccgc gacgacaccg
     8581 ccgcctagcc ctggtgcggg gcgacaggcg gctcttgccg cagggcagtc gatgaagccg
     8641 cgatccgtca acctacccgc cccacgccta atcgaacata cattcgacgc ggctgtgaag
     8701 gtggtgcgga gttggtggca cagcagctgt ggacggctcg cccgccgcga cgtatggctg
     8761 gtacgccaca cccggtggca ggtcgtcgcc cgcgccggcg acctcattgg aaaccccgcc
     8821 acgaggcttc aggctcctgg cgctatcgct gatggttttc cggtgaggcg cgaccgctgt
     8881 ccgctcgatg aagcgccttt gccacaactg cctcggccag cgctgctgat ctggagattt
     8941 cctgcacggc cgtttccggc agccctcctg gggcaaggcc cgcgccgacg gtgatgcgac
     9001 gcagatcggc acactggtcg ggcgtggtgc cacctatggg tccgcagaag ctgagaacgt
     9061 cccgagcggc gtagccgtcg gcaatgtcga tggcctgctg ggcggtctgg tagaggattt
     9121 ctgccgcgag tttgggccga gtaggcgtgg cgaggatcgc ggtggcgagt ccgagtcgtg
     9181 tgcggtagga cgcgtagttg ggcgcagata taggcgccgc gagttgttcg gtggcgaccg
     9241 tgaggtggtg agtggcgttt gcgtctgccg gtcctataca gatcacgttg aggcaggtgg
     9301 cgacctggtg ctcccatagc tgggtgagtg tgctgctgcc gaggattttg cgtccttgat
     9361 cgggtttgcc ctggatgcag gcggcgatga cggctgcttg tcgtccttcc atcaggtggc
     9421 cgccgatgcc gttgtgcttg cgagcgtgct cggcagcgcc ggcccaacgg ttgctcaggg
     9481 cgaggatgcg gatgccttcg ccgagcagtt gcagccagac ccactcgcgc agcttgcggc
     9541 gttctccagc gtcgccgtcg agggtggcgg tgggcagggc gtgtttatcc aggatgagag
     9601 cggtgcggtg ggtgacggcg tcgtacatgg cttcgaggag gcgcagtgct ggcacaccgt
     9661 ggtcagcgcg gatctggagg cgggcaaggt taaggaccgg ttcgagcatg taccgggctt
     9721 cgaggatcga gagcggccgg gccgtgcggc ggtaggcgtt gatgtgttgc cagcacagct
     9781 tcctggctag gtcaggcatg ccggcgtcgc tggcgatgag ggccgccttg ttgagggcgt
     9841 gtgccgcgtc gggcatcccg tgctcgcgct tctggactgc ggtgtcggcc gcgtcggcga
     9901 tttccttgat gcgcagcggc aaggccggac agtcggggcg cgggcgaccg aggagcggga
     9961 agtagcgcag ggcggcggcg acgctggcgt ggtacatggt tcaactcctg ggcaggatgg
    10021 cggcggtcgc ggcgtgggcg aggattcctt gtgcgtgggc tggtaggtcg agccggttcc
    10081 agtgaaagat cacgatctgg gccaggacgg cgcggatgcc tcggcggaga cgtccggcgt
    10141 gggtcgcgtc ggcgagctgt tggcccgctg cggcgaaggc cgcctgccag ccgctggcgt
    10201 cactgagagg tccgccggga gtgaacatcg ccgtgcgcgc gttcgccgga agcgcgagga
    10261 ggggccgcat ctgcgcggcg agtcggtcga tgcgggtcgc gtcggcggct gcggggacgg
    10321 gtcgcatctg ggctacctgg tcgaacatgt ccgccgcctc gtaccagtcg agtcccgcgt
    10381 ggtgctgcag ggttcggatg agcagcactg acagctcgcg gcggccgatc agtggcgcgt
    10441 ggtgtcgggt gtagttgagg acggctcggc tgtcggcgca gaacagctca tgcacgatgg
    10501 ccgtgctggt gtctccgccg aacgcggcgg tttcgggttc gtagatccct ggcttccacc
    10561 ccgcggtcac accgtcggcg gtgaggtcat cgagcaatgc gcgaacggct ccgtggtgag
    10621 cggcgcggat ccggaaccgc cagtacggat gtttgcgcag gaaccaccag ccggcctgcc
    10681 cgccaccaag tcgatcgagg tgcggggcga ggctcgaccg gaacacggcc tcggcggtgt
    10741 tccagtcgat cggcctgatt agggcctgct gccaggtgtc gtcgtgccgg cgttgcagag
    10801 cggtaagtcc ggcggtgcgg taggtctgca cggcggcgtc gaggtcgtcc acgtcgacgt
    10861 cggccccggc agccgcagtg gccatcggag ttcccgcgag gaccgcctcc acgagagcgg
    10921 ccatccggtg cgggctgacg gtcaggcgat cagtagacat gtgtcccacc tggtgcgggg
    10981 aggcgtgctc gtacgcgcgg cttctagcgc gagggaccag ccggactggc ctgtgagaag
    11041 cccggggtga tcagggctag ggcctcgctg gttgaggcgt tcagcgagcg tagggagctg
    11101 ggcggcgatg tcggctgtgc gggcgtcgcg gaccgcccgg tgcgcggtgg cgtagagccc
    11161 ggccaggccg tgacagatgc cgagttcggt gagccggtcg agttgaggcc cagtcatgct
    11221 ggccgcgagg gcggtctcgg ccgctacctg gcggtcgggt tggttagtgg cgatagccgc
    11281 gagttggagg gcgcgggcga tgccgggcgc gccgtagcac cacgacggcc taccaggtac
    11341 ctcttgtttg aaccggccgg cgcgtagttc gtcgcgggtg agccattgcg gccaccacgg
    11401 tccgtgggtg gtgtcctgct gccattggtc gaaccaggcg cacaggcgct caatcgcctc
    11461 ctcctgcccc ttgacctgcc ggccgttgcg cgtggcgagg gcgagcaggg ccagcaggcc
    11521 ggcggcgccg tgggccatac cgaaattggc gtggccgccc ggagtgggca tgagcggatc
    11581 ggggtcgtgg tcgacccacc agccgggaag ttgctgtccg tcgtcggtgc ggggctcggt
    11641 gagccctacg acgtaggtca gcgagtcgcc gagttcgtcg ctgtcaggca ggtcccgcag
    11701 caggagtgcg ccgagcccgg tgaggccgta gaacaggtcg tactcgttaa acgtggcggg
    11761 ttggccgtgt cggaggcgat tgtccgcgtc ggtgaggcgg tcgcggacga gccgccggac
    11821 gtgcggggtg aggtgttgtc gggcggcggt gtaccggtcg cggccgtcgg cggtggcggc
    11881 gttgagcatg aacaggatgg ccggcgcccc gtaatacaga ccggcgtggc gaccagcgtc
    11941 aacgcgatcg ccagtggcct gtgcgacgag atgacgcgcg gctgtccagt cgccagtgcc
    12001 ggtgagcgct cgctcgatcg ccaggagcgc gacgccgacc ccgccggtgg cgagcgactg
    12061 cccatcggct tcatccgctg cggtgacggg ctgctcggtg gcggcggtca tcgggtatct
    12121 gccgctgcca ggcagcgcat cgccgccgct cgcgcggcat ggttagtggc gcgctcgaag
    12181 tcggggtcta caccgacagc acgcacgtgg tgctcgtgca ggagggtccg tagcacggtg
    12241 gtggggtcgc gctgcggcag cagacgctcg tagtaggccg acaaggcgtg gtcgcgggcc
    12301 cgccaggcat cggcaatggc gtccccgccg ggcagagccc gcacgctgcg gtagtcggtg
    12361 gtggggtcgg ccagccggcg ggccaggtca gtgatcgtgc gctccgctgg tgccgcggct
    12421 tgttggaggc aggccagcag ggcgccgtat ccggtgtccg ggtcgggggc gaaggcggca
    12481 gccaggcgtg ccatggacgc tgcggcgagc gcttgcgcgg gtatgtcggt ctgctcggcg
    12541 gtgcggagtt gagcgatggc ggcggtggtg tcggcagcga agacctcttc ggcggcatgt
    12601 tgggcggggc cgtggccgta gcgggcggga tgctggtggt acggggcgaa gatgagttgg
    12661 gcgggtagtg cgcgacgggc gaggtcggcg gcgaactcgg ccaggatcgc gcaggcggcg
    12721 gcgtgcgcgg cgggttcgtt gagacggagg aacagggaca ggcgctggtc ggcttcgacg
    12781 cggatggtgt cgcggtcccg tctgatccac cagcgctgca ggccgaggcc ggcgagccgg
    12841 tcagccagcc ggggtaggtg tgtggtgagt agctcgtcga accgggcagg gttgccggct
    12901 atctgcgtgt ggatgaaggt ggaggtgcca ggccggagcg tgtcacccgg gggtgcggtg
    12961 accggtagtc gtcgggccgg cggcgcggtt ggtgtcatcg cgctgaggaa ttcggccggg
    13021 tggcctccgg tccagccgta gccgtctgcg ggggcgtctt cgcggagttc gagccgttcg
    13081 gcgccgccca gtcgggcgcg caggagagca cggtcgagcg gactgtccag gtcgaggggc
    13141 agctgtagct cgttctggca ggccaccacg cgggcgggca cgcgccagcg tcgccgccac
    13201 tcggttagag ccgcatccca ccggccctcg gtgtcgcctg cgccgggtgg cgtgtggggc
    13261 ggtatatcag cggcgttcag cagccagcgc gccggggcaa ggatgacgcg gcggtagcgg
    13321 atgcggggga tgtagggcag gttgcgggcg gctgcgccgt gatcgagggg gccgaaggcg
    13381 atgctgcggg cgtcggcgac ctcggcgagg aaccgggcaa gcggtggggt ttgcacgatg
    13441 gtgtcgaggg cgtgcggaat gtgcgggacg atccggcgac ccgtcggctg gtggacgagg
    13501 tacatctgtt cgctgtcggc tgtcacggcc acgtcgtcca ggctgatgtc cggccagtcg
    13561 ggctgctcgg acagcggaag cacgaagggc aggattcggc cgacgcgggt gacgttctgg
    13621 ttgcgcggaa gccggggcgg gaacgacacc tgcaccgcca attcctcgtc agcgtcccga
    13681 ccgcgggtac tgaacgaggc agtgacctgc tcctgctcgg tcggttcgag gaggtaggag
    13741 aatctgccgg ccatgcttga cggggtgcgt ggggcgccgg tgacctgcac cgtgaactcg
    13801 ccccggtcaa tggcgtcggc ggcggtggcg tgaacggcga aggccagctc gactcggggc
    13861 ggcctgacgg cggtgtggtg atcgccgacc gtgagcgcct cgatgtcggc gtcggtgagg
    13921 tggatctcgc cagtgttgtc gaggatcgcc tgctgaatca gcgcctgcag gtgcgtgtcg
    13981 cgttcggtga tgacccgcca ggcggggcgg gcgcggggtg cgccgaggta gccggtcggg
    14041 tagccgaggc cggagtcggc gagcaggtca cgcacgggta ccagcgcgcc ggggccgtaa
    14101 cggtcgcgga agcgggcgtg gtagtccagc cacgccaccg atccgaaggg ctgagtgctc
    14161 aggcgcagca gcaggtcgac ggcgagcgcc gcttcggcca gcaccggcgg cgggaggctg
    14221 atctgtgcgt cgaggcgcac gtcgatggcg agctggtgct cggcgttcgg cgccagcacg
    14281 gtcatcggct cggttaccgc agctcggatg agcatcgcct ccgagccgtc cacctgcgca
    14341 tcgtggcgcg ccagctcctg gcggatcgcg cagagctggt cgagactggc cgtcacctgg
    14401 ggcagctcgg ccgcctcggc gctgtgcaag gcgtcaatga cgtgggtcag gccgtccacg
    14461 gcggtcatgg gtgggcgaag gttggtgatg aggaagcctc catcgatcag gccgtgcaac
    14521 atcgcctcga cggtggcgac cgccacatga ggcacctcgt gcatgatctg tgcgaggagc
    14581 cgatcgaacc gaatcggcca cgcagcgact tgcagggcca gccttaccgc tgccgtgttc
    14641 ctggtggacg tctcacgcag cattcccggc gtccgctgcc ccaccggcgg ccaggcggcg
    14701 acgatgacgc ggccatcgcg caccacggcg gcgctgtcgg ccaccacgaa cagccgccgc
    14761 cgcagagcgt gatgcgcctc caagcggtca acaacgcacg tgagccattc gccgtctacc
    14821 cgtgccaccg cacgatgctt gtctccgaac gtcgcggagg ccgggccgac ggtggcggtc
    14881 gtgacggcgg cgaacagccc gaatggtgtt gtccgtcgct gccagcgcag caggtagccg
    14941 caggtagcga ggaccgcccg acgcacggcg gcggccgtcg tgccggacgc gtcggcggcg
    15001 aggagctggt cgacgcggcg ggccaggtgc gggctggcta tcgagatggc gtcccggacg
    15061 tcaggtcggc tccactggcc ggccagccag gcgagaccgg cctcggtgct cgccgcaggg
    15121 ccgatgaggt ccggcccggg ttcgggaccg aggttgccgg gatcggtgct ggcccggacc
    15181 aacgccgggc cgaccggttc aaaggtgcgc tggggcagca ttcgacgcct cctgccgcag
    15241 ggaagggggg atggccgccg gagcccgcga agcacgggct ccggcggcac agaggtgttg
    15301 cgggggcctg gtggtcaggc cgggtcgtac gacgaggtgg cgcaggcgct ggtgttgcag
    15361 gtgctgccgc agccgtcgct cgtgctgcag gccatgatca ccagcggcgt ggtcgcctcg
    15421 atcacccgca tgtcgagcac gaagtcgtcg tcggtgacga cctcggcgtc gatcggcggg
    15481 gcgtcgagga ccgcagtcgg cggagccatc gacatcactc tccttcccta caggggttgt
    15541 gtggtgccac ctggtcgtca ggaccaggag atcgagataa cgccgtgcgt cttgtccatg
    15601 accgcggcgt cggcggggat acgcgtgtgg tcgctgtcgg agggccagta gccgaagcgg
    15661 ggctcgacgt ggcgcccgtc gcgatcccag gcccggatct gctcgaccat cgcggcggcg
    15721 gctcgctcgc cgtcggggcc gaaggcgcgg gccccgaact cgaacccctc cccctcggtc
    15781 gcgggtcgca ccgccaggta ggcgaagccc gcgccgtgca cgacaccgaa gggaaaccaa
    15841 cggcgttcgg cggccaggtc ggttccctcg tcggccgcga cccggcagaa cccgggcagg
    15901 aaccacgcga accacaggtg cagatcggcg aacgacaccc cgttgccgat cgtcacaccg
    15961 gaccacagct cggtgcgctc catggcgagg acgccatcga gccggtccag ccggtcaggc
    16021 acatcggagt cgaacaacag ccggacgtgc cggccgttcg cgtcgggcag gaggaacacc
    16081 cggtccgggc gcgcgccggc accctgcatc ggtacgaacc cagcaacctc caccgacgcg
    16141 ctgatgaggt gatcgccgtc gcggcggaac ccgatcgtcc tcgtcaccgc gttcatgatc
    16201 agcggcagga cgatgacgcc gccctcacgg agctggtcga gcagggcggg ggcgatatcc
    16261 cacgccccga cggtgacgat gatcgcgtcg aacggtccct caccgggcac gccgtgctcg
    16321 gcatcggcga cgaggacccg cactcggctg ccgtagccgt tttcttccag caaggtcgcg
    16381 gcccggtcgg tgacctccgg atcgatgtcc acgctgacca cccgaccctg cggcccgacg
    16441 atctcagcga ggtacgcggc gttcagccca ccagagccga cctccaacac cgtcatgccc
    16501 gccgcgaggt cggcctgctc cagcatccgc gcctgaatgt aggccgcgga caccgacgag
    16561 atcgccacac cgtgctcgtc gcgcttggtc accacggagt tgtcgaagcc gtaggcgacg
    16621 tcgaggtcgg tgtcggaggg catgaaccgc tcgcgcggca cccggcgcac cgccgcttcc
    16681 accacctccg aggtgatttt cccctgggcg cgcaggtcgc ccacgagagc cgcgcgcagc
    16741 tcggcggcgc ggtcggcggc gaatcctgtg tcggctgtct ggctcactcg ctacttcctc
    16801 ttcctcgaag cgggtcggtc gggtcgggtc ggaacactgt tttccgctgg caacggccag
    16861 gacagcatcg acggtgcggc cagcggtgct atcgggtccg ggtgggccgg cggcaggggg
    16921 acgggggtgc ccgctgccgc cggcccgtga ccgaccatcc cgtggacacc ccggtcacgg
    16981 cggccggtca ggtagccgcc tcgcggcgac tacgggtgag ggctgatgga tttcgggtct
    17041 cctacagccc tggccatttg gaggctcagc gctcggcggg tggggaggct gaagtggctc
    17101 agcggctcgc ctcgccggcg cggcgggcct cattggttca ggtccccttg tgggcgtgca
    17161 cggcgcggcg ttcgtacgag ccgaggagca cgccggggtc ggccatgagg tcgatgaatc
    17221 ggccgagatc ggcgtggctg agttcgggct ggatcagcag gggccggagg tgttcggccg
    17281 cgtcggcgag gattcggcag ccgggaccgc cgccggccca ggtctcgatg cttcggtggg
    17341 tgcacacggt cttcatgccg ttggcgacga gcagctcggg aacgtcgttc ggccaggtgg
    17401 cgcgtccgcc cggatcggtg acgagcccgt agatcctcgt cacgagatgc tgaatcaggt
    17461 cggcgtcctc gcggtgcggg cggcggaaaa cccgagaggg agtgaaagga aggtcagcca
    17521 agataagcca gccgtcggga cgcagccggt cgatcatctg tcgaatcacg gcgttggagt
    17581 cgggcagggc gccgtgtagc caccgcgcga cggcgaggtc gaaggtgtcg gcttcgccgg
    17641 gcagctcgtc accgtcgagg ttgcgctggt agacgtcgat gacggcggtc ggagcgagat
    17701 agctggtgtc tttgtcgacc gcggtgaccc tgccgcttgg cccgacgagg cgggccagga
    17761 gggcggtgat ctcgccggtg ccggcgccga tttccaggat gcggtggccg ggccggatct
    17821 cgaggcggtc cagttcgtgg cggatggttg ggtcgagcag ttcgagcagt tgtggcggac
    17881 gcagccggcc gttgtgggtt gtcgtcatcc cgatgctcct tgtcgatccg attcgcaggg
    17941 cgtgtaggcg agggtgagca ctaccgggga tgcgcggggc atctcgcgcc ggtccagtgg
    18001 tggcggcggg ggtgcggtgg ggtcgacggg cggcggctcc caccatcggc ccggggagta
    18061 ggtgcgggtg agcaggagca ggtaggagcg tgtccgccag ccggcggacg tcaggcgagc
    18121 gtgctcgtag gccaggacag cgccggtgct cgggtgcaga atgagcaggt accgctcccg
    18181 gccgtcaccg ctgatcgtgc ggatgccgat gccggagcga ccggcgtggt cgagcgtgtc
    18241 gggatgcgcg gtcaggccgg cggtgtcggc gaggacccac gcggtaaggc cgcgtcgcag
    18301 cgggccaggg ttgtgccagg tgttcagcgt ggctagaccg tccatgagcg ccgcgttctc
    18361 gctacgccgg gaggtctgca ggtgtgcctg cgctaggagc cagtcggtgc tgtggtaggc
    18421 ccggaagagg ttcttgtcgt ggagccatcc ggacggccag aagtcgcggc gaaggttggg
    18481 gtgacgggtc aggggtgggt accgctgtgc cagttccgcg ccggagttgt cgtcggcgta
    18541 ccagcgcacg acgtcgcgca tgctcggttc accgccgctg ttgaaccagg cacggtggta
    18601 caccacgtcg taggtgccct cgaccgcatc gcaggtatcc ggggtgatcc gggctgcgag
    18661 gtcgagcagg accgggcggg ctggctggcc ggaccgcagc ctcgtcggcg gtggagtgcg
    18721 ggtgatcccg acgaggtagc ccttcggcat cggcacgccg cagccgtgtg gcggtgaggc
    18781 cagtagcggg aactgtccgc gagccggtgg gggcacacag cctacggcga gggctgcggc
    18841 aaggacagcc acgacgctgc ggcttgtccg ccggctgccc gccacggcgg gtgtccgagc
    18901 cgccgtcgtg cgcgtgtgta cgtcgccggg ctgggcacca ggcgcggcgg cgacaccctg
    18961 acgtgaacga ctctggctgc tatggggtac ggaattcatg acgtcctacc tggcgtcaac
    19021 tcgccgtgac gggcgtgccg aggcgtgata cgagctgcgc ggcctcgctg attgcggcct
    19081 gctgctgggg tgtgaggggc tcggcggcgt agccggcgac gacggcggcg agcgggtcgg
    19141 tgacgtgggt ggtggtgccg gcgagttctt cgaggaacgc gagggcgcag taggggacgt
    19201 accaggggtt gtatccgcct tcgtgggcgg cgatgagccg gccgtggcag agccggtcgg
    19261 ccgcgtcgat gagcagccgg gtcatttcgc ggtaggaggc ggcggtgagc atttgccgcg
    19321 ccagggggtc ccatacgttg gcgtcgaagc ccgccgcgag caggatcagg tccggtgcga
    19381 agcggtccag caccggcagg accacctggt gcatcgcgga caggtaggcg gcgtggccgc
    19441 tgccgggcgg taggggcacg ttgagggcgt agccggttcc gtagccggtg ccgttttcgt
    19501 gggtccagcc ggagtcgggt gggaagcacc cggcttggtg caggctgatg gtgagcacgc
    19561 tcgggtcgtc gtagaagatc gattgggtgc cgttgccgtg gtgggcgtcg aagtccacga
    19621 ccgcgatgcg ggccagtccg agttcggctt gggcgtggcg ggcggcgacg gcgatggagt
    19681 tgaacaggca gaagcccatt ccggcctcgg cggtggcgtg gtgtccgggc gggcgtagca
    19741 gggcgtagcc gttggtgatg tcgccgtgga cggcggcggt gacgagttcg atgagcccgc
    19801 ctgcggcgag gcgggcgatg tcgtagctgc cgtgcccgac cggggagaat ccgtctccgg
    19861 cgtcgcctcc ggcgcgtaga tcgctttggg ccttgatgtg ctgcacgtgc gcctcggtgt
    19921 gcacgcgcag cagttccgcg acggtggccc tgcgaggctc gatgctcatc agctcgccga
    19981 gcagccccga ggcgtggatc agctcgtgga cccgccgttt ggcctcggga ttctcgatgt
    20041 gcgcggcggg tgggataccg gcggccgggt tggcgggcag caggccggcg ctggtgccgg
    20101 tgtcgtgcca caggtactcg ggatggaaga cgtagccggt ggtcatggtg ggtgcccttc
    20161 gttagtcggg gccggtgccg aagcgggacg ggtcagtgcg cggggacgct ggtgggtgtt
    20221 ggcgtcgcgg gccggggtcg cgggatcggt ggcggtgcgg gggcggcggc gaggtcggcg
    20281 acgaaggcgt cgatctgtcc tcgggtgatg ccgggcatgc agatgaggtg gctggtgtcg
    20341 ccgtcggtgg ccaacagcca cttcctgcgt acctgcccgg gtggggtggg taggacgacg
    20401 gtgaaggcgt gcgggtgtcg ccaggcgggc cagccggcgg cgttgagccg gtcggtggtg
    20461 taggcggcga ggcggcgggc tgcggtggcc cgccaccggt gcccttcgcg gccgtgggtg
    20521 gcgatggcgt gccacaacag cgcggcagcc agcccgcacc gagaaccggt aatggtggtg
    20581 tccgccatgg cggtgtaggc gacacggcta ccgtgaatgc gcaggtggtc gcggatgagc
    20641 acgatcccgc acggggtggg aacgccgaag aacttgtgac ccgataccgc aatgctgctg
    20701 atgccgctgg cgtcatcgag gcgcagccgc ccgtcgaggg ccagggggat accggacagg
    20761 gcggcgtcga cgtgcaggtg cccgcccgcg tggtgctcgt cgaggaccgc gcggatgcgg
    20821 ccggtgtcat cgaccgcctc ggtcatggtg gtgccggcgg tcgccacgac gatggcgggc
    20881 cagcgacgcc gcctgcgtag ctgtgcggcg aggtgcgtgt agtccatctc cccgtcgggc
    20941 tgcgcgtgaa cggaaacgcc tcgggctccg agcaggcgca ccaccttcgg tacggagtag
    21001 tgggcggcgg tcgagtagta gatgcgggcg gtggggtcac gccggtgcgc ggcgtgcagg
    21061 gcggacaggt tgccttccgt gccgccgctg ctcacgtagc cccaccggtc gtcggcgggc
    21121 atggcgagca ggtcagcgac ccaggtgatc accgcgcgtt ccagggcccg cgtgtgggcc
    21181 acgccgccgg tgtcggtggg gtcgccgatg ttgttccaca gcctgccgcc gaggcgggtc
    21241 atgacctcgg tgtggtcgag gtccacggcg ccggggaatc cgatgctcgt ggccgccgcg
    21301 gcgtcggcct cgcgtacgag gtgatcgaga acggccgtga tgtcgatctg cgcgcggctc
    21361 aggtccgcgg cgtcagggag gttcagagtg tgggtcacgc cggcagcccg tgaaggtgcg
    21421 cggtgagggt gtggtgcagc gcgccgaggt gccgccacac cgctcgggtg gcgtcgtcgc
    21481 cgtcctcggt gaggttctcg tgccggttgt agtaggtgac gcggtccggg tcgagggtgc
    21541 ggttgcagcg gatgccgtcc acgcccaggc acgcgtgcgg gtcgcggtcg atgtgcaggg
    21601 cggtgccgtc ggtcagcagc acgtacgcct gacctttgag gtcgaagacc gacaggcggt
    21661 gtccggtggc gggtaggtct cgcagggtgt gggcgagctg gtaccagcgg ccctggtcgg
    21721 agtcgagggt gctgaccccg gcaccgacgt aggtcgcgtg ctcgggcagg ctcatgtccc
    21781 cgccgttgac catcgagccc tcggggccga ggggatgcca gcggcgccgc gcggaggctg
    21841 cgcgggtgat gttgtcccgg gctacgccgt cgaggtccgc cagcaacctc gggaggtcgt
    21901 ccgcgtctgg ggaggccagc cacagccggt aggcggtgtg cagccggtag ccgtggggct
    21961 cgcccggcgc gtcggagacg aagaacaaca ccaccccgtg cgggccgagc gcctcacgcc
    22021 caccgaaccg ttgatccgcc tcgaccatgt gaccggtgtt gatccgcttg caccggtacg
    22081 cgacctgctt gcgcaggtcg gcccagcggc ggacctccgg cggcaccctg tcatcgacag
    22141 gcacgtgctc gtacggcgga gccgacacgg tcgggtgcat gggctgcgcg gacgggggcg
    22201 ggggaagcat ggtctccggc gttcgcgagt agtcggccgg catccgcgcc gtcccgtagc
    22261 cgggccccgg cgcgggggcg gtaggccccg gcgggtgagc ggcaggccct aacccgtacg
    22321 ccgggtgttc catcggcacg gcgggcggtg ccgtctgcgg gtgctccggt cgccatccgg
    22381 cttcggcttg ctcgacgctg tagtgcctgc ctggaggcgg tgtggccgcg tgggtcatca
    22441 tcgtcgcccc cttgtcagat cgagacgctg atcgcgtcgg gaacggcgtg cgtgctcggg
    22501 gtgccacggc cgataccggc gtagacgtcc ggacgggact gccgcagatg ccccgcccac
    22561 accccgccga ggacggcggt ggcggcgagg atcgtgggca gcaggaacgg atacagcgaa
    22621 cccggcgcgg caccgagcag ggagccggcg ttgccgacca tcagtcccag cagcaccagc
    22681 ccgcccagca cccccaacgc gggtgcgagc cgccactccc acgcgccggc ctgtgggccg
    22741 cgcacgctcg ccggtgccac catcgccgcg acagaggcgg ccagcagcag gcacagcagg
    22801 cccatcgccc ccagcgtcga cagccacgtg aacatcaccg cgatcggctc agcgccagct
    22861 agcgcgaacg cgcccaccac caccgaggcg atggctgtct gcgtcaacga gccgccgcgc
    22921 ggcgcgctga cccgggccgt gctgccggtg cgcgcgagag cggcgggcag gacgccttcg
    22981 cgcgccaggg cgaacacata ccgggcgaca acgttgtgga agaccagctt cgaggtgagg
    23041 atcgcgagga tcaggaccag ctccgcgagc accacccacc caccgccgag gcgttccagg
    23101 atcgagaacg gcagccctgc cgccgggttg gcagccacct cgccgacggc gtcggggccg
    23161 accgccacgc ccatcgccca cgccgcgagg gcgtacacgc cgccgaggac gaccaccgcg
    23221 ccgatcgtgg cccggcctac cgaccggcgg tcgacggcct cctcgaccat cgatcccggg
    23281 gcgtcaacgc ccatcaacgc cgccacgcag aaggccaccg cgccgccgac gccgctgacc
    23341 gccagcccca aggcgtcgaa gcccgcccac gacagcccgc tgtcagccgg ctgccccaca
    23401 cctgcaagga cgaacgcggc gacgatcagc agcgacaccg ccagcacggc caccaggacc
    23461 cgggtggata gcacgatcgc ccgcgtaccg aaggccccga tcacggccag ggcgaggccc
    23521 gcccacaccc accaggcccc accgagttgc ccggccagcg tcgccccgac caacccgtac
    23581 agactgatct gaatagcgtt gtaggcaacc agggcgacca ggccggcggc gacaccccag
    23641 ccgcgcccga ggctgttggc gaggatgccg tagtaggccg ccgggtgtcc cacctgccgg
    23701 gccatcgccg tataccccac cgccagcaac gccaccaccg ccgcgacgag cacgaacacc
    23761 agtggcagcg ccgtcacccg cgtggtcgcg taggtggcga cgatgcctcc ggcgagcacc
    23821 accgtcggcg ccgacgccgc cgccccgaac acccacaacc cgacaggagt cagcgttcgt
    23881 cgggcgagcg ccacctgcat gtgcgtcgag ctcaccgctg cccccgctcc accaaatccg
    23941 ggcaacacga gagccggcag ccatccaccg gatgcctgct cacgtccgcc gcattcgctg
    24001 ggacgagaaa caccgccgcc ggacgtaccg ggccgccgcg ccagtagctc cggtcacggt
    24061 cgagccgccg ctgcgcggtc tcgacatcgg gggtgaagcc gaacaggtcg tgagaaccat
    24121 tggcccactc ccgtcggatc gcataccccc acgcgaactc gtccgacgtc acgtctcccg
    24181 cgtccgtcac ggcggcatcg acacgcgcag aggacggcca gggtggcagc caccgtccgg
    24241 cgttgcaccg tggcggggcc aaggctcgta tacgggtcag agcggacagc atgagggatg
    24301 cctccttcga tagcagggcg cgaaagggtg agccagcgag gtcatcgcca gcaggtgctc
    24361 aaccacgggg tggtcggacg atcagggaga acgaggtgac gccggcacgg cacgacgacg
    24421 cagcggcata gcggagcgat gcgcgcgcac gcggcacggc aacccgtcgg accgacggtc
    24481 gccaggagca ggccgccaca tccgccacag cgccggaccg ccgggctcca acaacaccgg
    24541 cgaccgcggc tcatacccga gccgagcgaa cacgctgtct cgcggccggg caccgctgac
    24601 ctccgcgtac gccggcagcc cctccgcgtc gagcctgcgg tgatagctgg ccagcaaggc
    24661 acctgcagca ccgctctgcc cgggaccagc cgcgagatga gccaggtagt gatgcggcgt
    24721 atgcggaagc accgcatcga cgtaggcgtg cagcaacgcg aaccggggtg cgtgcgatcc
    24781 gaggatccgt tgcaggtcgt acacccacca cgcagccggc accggcggct ccaaccgcga
    24841 ataccaaacc gctacagcgg agtggtcgtc ggtcgcggca acctggccct cgtccaaccc
    24901 gcgcgtcagc acaagtcgtg cgtagcggcg cagaacaccg gaacgctgac ctgcatccgg
    24961 gaccagccag gcggccgtcg gttgggccaa cagcgcatcc atcacgaccc ccgacagcgc
    25021 ctcaacgtcc tcactggtcg cgctgcggac cgccgtcccc gaaggcatca tgtcgcgtcc
    25081 ctcgcggatc ggctcgggcc gctgtttcca tcatccgcgt ccgccacctc cgactcggca
    25141 gcgtgtgcca cccgttgccg ggacatccgc cgggccgaat caagcgcgcg ctgaaaggtt
    25201 gcggcgacgt gcagactttc c
//
