LOCUS       NZ_GL622296.1          20144 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_GL622296.1 Lachnoanaerobaculum saburreum DSM 3986 SCAFFOLD1,
            whole genome shotgun sequence.
ACCESSION   NZ_GL622296
VERSION     NZ_GL622296.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:54:59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 156662
            Orig. end    :: 176806
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20144
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[166662:166806](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10144)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20144
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20144
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             1005..1712
                     /locus_tag="ctg1_157"
                     /transl_table=11
                     /translation="MGEASRKIGSLIRQFRQSKALTIEELAERINKSRATLSKYEKGDI
                     VLDVDTLYDISDALGIQAEQLLYRKNKEFSFNNKRINPGFFQNIEQFYAYFYDGRNKKI
                     NRSVIDIIRNSDVNSYEVAMYMNCSDLNNYHKSENTYWGFMEHYDTMTLLEVTNQDTPT
                     EKASIQILASFLDAEVKWGLWNGVSSRPLMPVALKMLFSKKALKEDKELVQLLKVSKED
                     YQNLKYYNFFCVF"
     PFAM_domain     1038..1196
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_157_0001"
                     /evalue="1.60E-13"
                     /label="ctg1_157"
                     /locus_tag="ctg1_157"
                     /protein_end="64"
                     /protein_start="11"
                     /score="50.5"
                     /tool="antismash"
                     /translation="IRQFRQSKALTIEELAERINKSRATLSKYEKGDIVLDVDTLYDIS
                     DALGIQAE"
     CDS             complement(1835..3052)
                     /NRPS_PKS="Domain: Aminotran_1_2 (67-394). E-value:
                     7.7e-36. Score: 115.7. Matches aSDomain:
                     nrpspksdomains_ctg1_158_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 153.3; E-value:
                     1.5e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_158"
                     /transl_table=11
                     /translation="MYNFDEIIDRRNTNCLNTDGFRGYIFHAEPEKKFPYKDEEFVRMW
                     VADMEFAVAAPILEALRERIDRKIFGYTGVYDDSYYQSFKKWCEDHYKWSFPKDELCFS
                     PGIIPAMYQLVETLLTKNEKVLVNTPSYGYFLHAAEYSGVEVLQSPLKKDKNGRFVLDY
                     ENFEKQCADPACKLVFWCNPHNPTGRMWTEEELRRCGEIMMQYNLWVISDEIHCDLIRQ
                     GKQHIPMAKVLDNYPKLITCMAPSKTFNLAGLAFSNIIIRDPQLREIFKNRDKLFGMVN
                     PMSLVAAKAAYDRGGEWHEELKIYLDKNFEFVKEYLSTNLPEAVMGISEATYLAWVDLS
                     AVLPDVKDLPGFFANNAGVLLEGGNSLFVGNADGYIRLNLAMPQAIIKTGLERICKSIE
                     EYKNKI"
     aSDomain        complement(1871..2851)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_158_Aminotran_1_2.1"
                     /evalue="7.70E-36"
                     /label="ctg1_158_Aminotran_1_2.1"
                     /locus_tag="ctg1_158"
                     /protein_end="394"
                     /protein_start="67"
                     /score="115.7"
                     /tool="antismash"
                     /translation="KIFGYTGVYDDSYYQSFKKWCEDHYKWSFPKDELCFSPGIIPAMY
                     QLVETLLTKNEKVLVNTPSYGYFLHAAEYSGVEVLQSPLKKDKNGRFVLDYENFEKQCA
                     DPACKLVFWCNPHNPTGRMWTEEELRRCGEIMMQYNLWVISDEIHCDLIRQGKQHIPMA
                     KVLDNYPKLITCMAPSKTFNLAGLAFSNIIIRDPQLREIFKNRDKLFGMVNPMSLVAAK
                     AAYDRGGEWHEELKIYLDKNFEFVKEYLSTNLPEAVMGISEATYLAWVDLSAVLPDVKD
                     LPGFFANNAGVLLEGGNSLFVGNADGYIRLNLAMPQAIIKTGLERI"
     PFAM_domain     complement(1871..2851)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00155.23"
                     /description="Aminotransferase class I and II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_158_0002"
                     /evalue="2.70E-33"
                     /label="ctg1_158"
                     /locus_tag="ctg1_158"
                     /protein_end="394"
                     /protein_start="67"
                     /score="115.7"
                     /tool="antismash"
                     /translation="KIFGYTGVYDDSYYQSFKKWCEDHYKWSFPKDELCFSPGIIPAMY
                     QLVETLLTKNEKVLVNTPSYGYFLHAAEYSGVEVLQSPLKKDKNGRFVLDYENFEKQCA
                     DPACKLVFWCNPHNPTGRMWTEEELRRCGEIMMQYNLWVISDEIHCDLIRQGKQHIPMA
                     KVLDNYPKLITCMAPSKTFNLAGLAFSNIIIRDPQLREIFKNRDKLFGMVNPMSLVAAK
                     AAYDRGGEWHEELKIYLDKNFEFVKEYLSTNLPEAVMGISEATYLAWVDLSAVLPDVKD
                     LPGFFANNAGVLLEGGNSLFVGNADGYIRLNLAMPQAIIKTGLERI"
     CDS             complement(3138..4586)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038:phenylalanine-specific permease (Score: 106.6;
                     E-value: 1.8e-32)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_159"
                     /transl_table=11
                     /translation="MFITKSAAQYILRDMIFHFHKEAKLNKETSKKIGLWNVVGLGVGG
                     AVGSGIFITLGTAIASTGRSILPMTVICVFYMLLAYWYNLALSGIFIVNGGDYSMKGML
                     LPPILIGYGGWTNVIWAFGFTGYALGLTSYLSSLWPVLGEHGKLTSAAILTLFFLLSIK
                     GNRIVALFQNAATIFLIGALMLFVILGIPKVDINNFFDMSYDGGFFHNGFFGVINAIAI
                     MGWACQGTTMGPVGVIPITKNPKRTIPMGILITCVVVSIIYGLMSFAAAGVLPYDEVAG
                     QNLSVTASVIMPKGMFAYFVLGGGVCAIVSSFLAVLAMIREPIAHMADDGWLPAIFKEK
                     TADGYPKYCFLIVYIIALVPILTGMSVNNAISMLMIPSMLINAFLNVYCITIPRKYPKQ
                     FEKRSIKCPAVIYDICCILGGICALIVASTLFGGLTIYDMITAAAIILIPLLFSAIALK
                     KGAVSKESLDKRREEIVKEALLEE"
     PFAM_domain     complement(3261..4490)
                     /aSDomain="AA_permease_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13520.8"
                     /description="Amino acid permease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_159_0003"
                     /evalue="7.70E-30"
                     /label="ctg1_159"
                     /locus_tag="ctg1_159"
                     /protein_end="442"
                     /protein_start="32"
                     /score="104.2"
                     /tool="antismash"
                     /translation="IGLWNVVGLGVGGAVGSGIFITLGTAIASTGRSILPMTVICVFYM
                     LLAYWYNLALSGIFIVNGGDYSMKGMLLPPILIGYGGWTNVIWAFGFTGYALGLTSYLS
                     SLWPVLGEHGKLTSAAILTLFFLLSIKGNRIVALFQNAATIFLIGALMLFVILGIPKVD
                     INNFFDMSYDGGFFHNGFFGVINAIAIMGWACQGTTMGPVGVIPITKNPKRTIPMGILI
                     TCVVVSIIYGLMSFAAAGVLPYDEVAGQNLSVTASVIMPKGMFAYFVLGGGVCAIVSSF
                     LAVLAMIREPIAHMADDGWLPAIFKEKTADGYPKYCFLIVYIIALVPILTGMSVNNAIS
                     MLMIPSMLINAFLNVYCITIPRKYPKQFEKRSIKCPAVIYDICCILGGICALIVASTLF
                     GGLTIYDMITA"
     CDS             complement(4970..5560)
                     /locus_tag="ctg1_160"
                     /transl_table=11
                     /translation="MIMGESKDYEVRKRAEIIEKQGIRCRTLVENLNFLNKLDYGSVKF
                     EKKNIQISTLLRKCVTQILNALEEDVFSFELDIDESLQKECFLINEDFTERAIINLLNN
                     SIKHNPKGCNIQIKLYKNEKNAIVLSVEDNGAGVSRELLKKLNKKSYETERSEGNHGLG
                     LKIVKQVASRHKWKISFHEGEMGGFVCEMILKN"
     PFAM_domain     complement(5000..5290)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_160_0004"
                     /evalue="5.40E-17"
                     /label="ctg1_160"
                     /locus_tag="ctg1_160"
                     /protein_end="187"
                     /protein_start="90"
                     /score="62.4"
                     /tool="antismash"
                     /translation="EDFTERAIINLLNNSIKHNPKGCNIQIKLYKNEKNAIVLSVEDNG
                     AGVSRELLKKLNKKSYETERSEGNHGLGLKIVKQVASRHKWKISFHEGEMGG"
     CDS             complement(5584..6168)
                     /locus_tag="ctg1_161"
                     /transl_table=11
                     /translation="MNNLGLIILVIMTIFALLFIDLILYGIVMYKSALSLYYPKVNIME
                     NLLFEEGKYKLSDEAVESLRERGEFAMLLDNSGNILWSEDLPKELEKEYTLQDVARFTR
                     YYLNDYQVHTYVVSPGLLVVGYRNKNIWKYTLEYYEDSLLLSIKMTPFLILGNVVLLII
                     ISLGLYRRQIRQREEEGCNGLPESPMIFALP"
     CDS             6320..6655
                     /locus_tag="ctg1_162"
                     /transl_table=11
                     /translation="MSIVNTLSLESNRKIKINFDGGDLSSDAALLLIKEFVSKLGIDKL
                     FSQSFKTNDSALFRYHTDKENLFQMIYMIIAGYFEDDSSDELTNDPVFKAVLNKDTLIT
                     TDHFKIL"
     PFAM_domain     6341..6622
                     /aSDomain="DDE_Tnp_1_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13701.8"
                     /description="Transposase DDE domain group 1"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_162_0005"
                     /evalue="1.20E-25"
                     /label="ctg1_162"
                     /locus_tag="ctg1_162"
                     /protein_end="101"
                     /protein_start="7"
                     /score="89.7"
                     /tool="antismash"
                     /translation="SLESNRKIKINFDGGDLSSDAALLLIKEFVSKLGIDKLFSQSFKT
                     NDSALFRYHTDKENLFQMIYMIIAGYFEDDSSDELTNDPVFKAVLNKDT"
     CDS             6732..7634
                     /locus_tag="ctg1_163"
                     /transl_table=11
                     /translation="MPEAIILDLDSTLLNAYGKQEGRAFNFHYQSNGYHLLVCYDGITG
                     DLIKIQLRDGTQYSSTGVVDFLQPILDEYLEDFPEIKLLPRGDSGFATPGLYKQYEENG
                     TGYVICLKENAILRDKASYLVDEITKNNKVDYAVVYGELMYQASPWPYERRAVCKVEKT
                     ENQMTYMYTFIVTNMESSPEYLIKFYCKRGLIENFIKESKTGFDFASVSSHTRIVNANR
                     LQLHALAYNIFNWFRRLALSVNMRKQRIDTVRLKPLKIAAKVIRSARYVTFKLCSSCPY
                     KDEFYKPLSNISKLFIQLE"
     PFAM_domain     6735..7616
                     /aSDomain="DDE_Tnp_1_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13701.8"
                     /description="Transposase DDE domain group 1"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_163_0006"
                     /evalue="3.30E-98"
                     /label="ctg1_163"
                     /locus_tag="ctg1_163"
                     /protein_end="295"
                     /protein_start="1"
                     /score="328.9"
                     /tool="antismash"
                     /translation="PEAIILDLDSTLLNAYGKQEGRAFNFHYQSNGYHLLVCYDGITGD
                     LIKIQLRDGTQYSSTGVVDFLQPILDEYLEDFPEIKLLPRGDSGFATPGLYKQYEENGT
                     GYVICLKENAILRDKASYLVDEITKNNKVDYAVVYGELMYQASPWPYERRAVCKVEKTE
                     NQMTYMYTFIVTNMESSPEYLIKFYCKRGLIENFIKESKTGFDFASVSSHTRIVNANRL
                     QLHALAYNIFNWFRRLALSVNMRKQRIDTVRLKPLKIAAKVIRSARYVTFKLCSSCPYK
                     DEFYKPLSNISKL"
     CDS             complement(7957..8742)
                     /locus_tag="ctg1_164"
                     /transl_table=11
                     /translation="MINILLDNNFKINIERNNDYMKNISKIMVTALSCFMIAIPITNNI
                     YADEENTSTEYQSLQVGDSYSVIEDIDALGFPADYDDFVDKIKEIKDSNPDLSPEQILK
                     EYEDMYCNTAQPAGWYESWTALTLSEKILIATNPVNAAITKELANNAVAKTAELYGYNG
                     LGDNTDAFRHAYWNALMTARINKGWAAAYATAPEDRNTSGNESDGYSKVAHKKMDLHNN
                     KKDRNLVKWNDLLTKDEVFAQRVQGIMTNNASTGLYWLH"
     CDS             complement(8761..9213)
                     /locus_tag="ctg1_165"
                     /transl_table=11
                     /translation="MNNLGLVGVIMIFYKNSLFLILLLSALYLSGCEKTQNNGSILYYE
                     QNKFEVDIKQLIDNRYYIINNSDNYNFYYRTYGDIIFYSKLKVNVITYENSILKINLKA
                     IPVYSDDEVSSEIFVNIPNFKENVDKVIVDVNSDTAEEVYHGESRL"
     CDS             9365..9976
                     /locus_tag="ctg1_166"
                     /transl_table=11
                     /translation="MSILNTISLESNKKIKINFNGGNLPSDVGLLLIKEFAAKVGLIKL
                     VKKLFKTNDHTNSRIHTDSDNLMQMLYQIIAAYFEDDCADELTNDPVLTSILEKEALAS
                     QPTLSRFWNRMDNDTLTQLDSINAKMRDIVYSIKAPEHMFFDLDSTLLNTYGKQEGEGF
                     NFHYQAHGYHPLQLLSFVLIQMHKFPYHLPEKYYFRSHIV"
     PFAM_domain     9386..9892
                     /aSDomain="DDE_Tnp_1_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13701.8"
                     /description="Transposase DDE domain group 1"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_166_0007"
                     /evalue="5.00E-52"
                     /label="ctg1_166"
                     /locus_tag="ctg1_166"
                     /protein_end="176"
                     /protein_start="7"
                     /score="176.7"
                     /tool="antismash"
                     /translation="SLESNKKIKINFNGGNLPSDVGLLLIKEFAAKVGLIKLVKKLFKT
                     NDHTNSRIHTDSDNLMQMLYQIIAAYFEDDCADELTNDPVLTSILEKEALASQPTLSRF
                     WNRMDNDTLTQLDSINAKMRDIVYSIKAPEHMFFDLDSTLLNTYGKQEGEGFNFHYQAH
                     GYHPLQ"
     CDS             complement(10001..10144)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_167"
                     /sec_met_domain="TIGR04223 (E-value: 1.8e-14, bitscore:
                     50.8, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKYLLLISKGIALCSFVFALFNANSACAFIYHQPELPDKVKKLR
                     KF"
     aSDomain        complement(10016..10126)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_167_0001"
                     /evalue="2.80E-14"
                     /identifier="TIGR04223"
                     /label="ctg1_167"
                     /locus_tag="ctg1_167"
                     /protein_end="43"
                     /protein_start="6"
                     /score="50.8"
                     /tool="antismash"
                     /translation="LISKGIALCSFVFALFNANSACAFIYHQPELPDKVKK"
     CDS             complement(10782..12047)
                     /locus_tag="ctg1_168"
                     /transl_table=11
                     /translation="VSLVHSVFLVSNILGTFSIFKLISIFFERENIYKCVEVLSYVIYY
                     ILSVLIFTFFPVPVVLLSFNIISIFAITLNYSGTLKRHITATVYVYLIIFGIEIMVMSL
                     FEYKKIFIFKVQELHSVYLIICVKVLVYIVALILSERKFNIKKSGEISPLYWIGVVSIP
                     VASLVVMILFLNIATGSEQLHILIVLLSIAIINIVSFQLYNHVVSIMQEKNKKLLLQKQ
                     DEAYLQQLKMIQANNENISLIRHDIQNHLFMLKSLYEKGEIDSYRDYLDTLLSKIDKKE
                     EVCKSGNLVVDSIINYKLRNINDINLYIDVCIPKKLEISDVDMTVALGNLLDNAVRAVK
                     ESDRKELKINLKYKKGRLILQIENSYKNIVKSQGKLQTTKKEKQGHGIGLESVREVAER
                     YNGIMQIDYEDNLFVVLVILYC"
     PFAM_domain     complement(10791..11093)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_168_0008"
                     /evalue="2.00E-26"
                     /label="ctg1_168"
                     /locus_tag="ctg1_168"
                     /protein_end="419"
                     /protein_start="318"
                     /score="91.9"
                     /tool="antismash"
                     /translation="ISDVDMTVALGNLLDNAVRAVKESDRKELKINLKYKKGRLILQIE
                     NSYKNIVKSQGKLQTTKKEKQGHGIGLESVREVAERYNGIMQIDYEDNLFVVLVIL"
     CDS             complement(12050..12772)
                     /locus_tag="ctg1_169"
                     /transl_table=11
                     /translation="MFKIAVCDDIKATCDELKEIILSKAKGVLHENISVDIFYSGDALI
                     SDIGEGNLYDLIFLDIELGGKINGVEIGHIIRDEMDDYITQIVYISSKNNYDRQLFDVQ
                     PLHFLQKPIDVSKLLNDIKLAIKISGKENKIFEFKNLRNTVKVPYKDILYFESKGREIS
                     LVSCKMQYTFYDNIQELSKVLPDFFIYPHRSYLVNYELIACFKYEELIMSNGDIIPISR
                     SKRKEIRKLQMMFERKGL"
     PFAM_domain     complement(12080..12346)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_169_0010"
                     /evalue="1.70E-17"
                     /label="ctg1_169"
                     /locus_tag="ctg1_169"
                     /protein_end="231"
                     /protein_start="142"
                     /score="63.5"
                     /tool="antismash"
                     /translation="NTVKVPYKDILYFESKGREISLVSCKMQYTFYDNIQELSKVLPDF
                     FIYPHRSYLVNYELIACFKYEELIMSNGDIIPISRSKRKEIRKL"
     PFAM_domain     complement(12407..12763)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_169_0009"
                     /evalue="1.70E-10"
                     /label="ctg1_169"
                     /locus_tag="ctg1_169"
                     /protein_end="122"
                     /protein_start="3"
                     /score="41.1"
                     /tool="antismash"
                     /translation="IAVCDDIKATCDELKEIILSKAKGVLHENISVDIFYSGDALISDI
                     GEGNLYDLIFLDIELGGKINGVEIGHIIRDEMDDYITQIVYISSKNNYDRQLFDVQPLH
                     FLQKPIDVSKLLNDI"
     CDS             complement(13018..13791)
                     /locus_tag="ctg1_170"
                     /transl_table=11
                     /translation="MNLIGCEFIKLKRYNIMWIGIVAVIFAVVISVFQNFEGVKTLSYN
                     EFFNSVIWNNFSISFPFSITLIGGYMIDHEYTDDTLKNIMTVPVSMRRLLLAKMICVGV
                     ISAILGLFSFICTLAAAKFFLSCKEMGSEVIGVSCIQISLIAVFNFIAVSPLIAFFSRK
                     RGGFYVGVGLAFFYGLCGIFAAGRHLTDVYPVTAGLGIISYAQGAYNPAIGCISLMLMI
                     LVTAILIFYTPDYDKIMSSVLKDSTKQKETTKGMG"
     PFAM_domain     complement(13249..13785)
                     /aSDomain="ABC2_membrane_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12730.9"
                     /description="ABC-2 family transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_170_0011"
                     /evalue="7.20E-37"
                     /label="ctg1_170"
                     /locus_tag="ctg1_170"
                     /protein_end="181"
                     /protein_start="2"
                     /score="127.2"
                     /tool="antismash"
                     /translation="LIGCEFIKLKRYNIMWIGIVAVIFAVVISVFQNFEGVKTLSYNEF
                     FNSVIWNNFSISFPFSITLIGGYMIDHEYTDDTLKNIMTVPVSMRRLLLAKMICVGVIS
                     AILGLFSFICTLAAAKFFLSCKEMGSEVIGVSCIQISLIAVFNFIAVSPLIAFFSRKRG
                     GFYVGVGLAFFYGLCG"
     CDS             complement(13806..14561)
                     /locus_tag="ctg1_171"
                     /transl_table=11
                     /translation="LLKLVGCEFKKLRRKRFIKLTIAAACLFPTPLIIAMAKDGQSFIQ
                     LFRAVVMFDDILFLPCVLGIVAIILFSMEQDSDTLKNLLVIPVSKTNIFLTKLTVLFLL
                     SLIYTLAAYAASLIGGLIIGKISDVPFLFSVSIGLGIFVFLATVPVIAIIIVCNKSKVF
                     SIIIVLIYAVLGFVTVQTIGRGSVLDRLTFALPICITGKWYLGIVPVEQALSYILPYTL
                     STPVAFGLLVAYGIAFTLLSLFSYKRTEI"
     PFAM_domain     complement(14037..14552)
                     /aSDomain="ABC2_membrane_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12730.9"
                     /description="ABC-2 family transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_171_0012"
                     /evalue="7.80E-39"
                     /label="ctg1_171"
                     /locus_tag="ctg1_171"
                     /protein_end="175"
                     /protein_start="3"
                     /score="133.6"
                     /tool="antismash"
                     /translation="LVGCEFKKLRRKRFIKLTIAAACLFPTPLIIAMAKDGQSFIQLFR
                     AVVMFDDILFLPCVLGIVAIILFSMEQDSDTLKNLLVIPVSKTNIFLTKLTVLFLLSLI
                     YTLAAYAASLIGGLIIGKISDVPFLFSVSIGLGIFVFLATVPVIAIIIVCNKSKVFSII
                     IVLIYAVLG"
     CDS             complement(14554..15477)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 168; E-value:
                     4.6e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_172"
                     /transl_table=11
                     /translation="MSLYIIETRHLTKQYGTQKSVADLNIHVKKGRVYGLLGRNGAGKT
                     TTMKMLLGLTKPTIGEVLLWGEPLHGNENKVLPRIGSMIESPGFYPNLTGTENLSIFAI
                     LRGVPNNHSIQDALNLVGLPYKDKKLFSQYSLGMKQRLAIALAVMHDPELLILDEPING
                     LDPIGIAEVRKFIRELCNKRGKTILLSSHILSEIALLADDIGIIDRGVLLEEETFAELE
                     QKSSRHIHFTVSDSAQAAMVLEKTFNETHFLVHDDHNLNLYNLDLPVGKIVAAYVETGL
                     EVSEAHTCEETLEDYFKRVTGGEGIA"
     PFAM_domain     complement(14992..15411)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_172_0013"
                     /evalue="4.80E-28"
                     /label="ctg1_172"
                     /locus_tag="ctg1_172"
                     /protein_end="162"
                     /protein_start="22"
                     /score="98.5"
                     /tool="antismash"
                     /translation="DLNIHVKKGRVYGLLGRNGAGKTTTMKMLLGLTKPTIGEVLLWGE
                     PLHGNENKVLPRIGSMIESPGFYPNLTGTENLSIFAILRGVPNNHSIQDALNLVGLPYK
                     DKKLFSQYSLGMKQRLAIALAVMHDPELLILDEPIN"
     CDS             complement(15581..16498)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 160.7; E-value: 1.2e-48)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_173"
                     /transl_table=11
                     /translation="MEVLIIVLTFVTMLVIIYSVLILHRERQQIGEISKALLDVRNGNG
                     NRRILAYPGQLLSPLVYEINDIIRAYEDKIAVFQQTDEMNKQLMTSLSHDVRTPLTTLI
                     GYLDAVHKGSVTGSEREEYIEISRHKAYDLKGYIDVLFDWFKLNSDEFAMEIQSVEAAE
                     LTRNILIDWIPLLEEQGIEYSIEIPDQAVTVNLNQDSYLRIINNLLQNVITHSMADRID
                     VLFTKHEGVMRLSVEDNGIGIGKEELKHIFSRLYKCDKSRSNKSSGLGLSIAYQLAEKM
                     GGQLCVESGLGKGTTFILTLPLLK"
     PFAM_domain     complement(15590..15895)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_173_0014"
                     /evalue="7.20E-22"
                     /label="ctg1_173"
                     /locus_tag="ctg1_173"
                     /protein_end="303"
                     /protein_start="201"
                     /score="78.1"
                     /tool="antismash"
                     /translation="LRIINNLLQNVITHSMADRIDVLFTKHEGVMRLSVEDNGIGIGKE
                     ELKHIFSRLYKCDKSRSNKSSGLGLSIAYQLAEKMGGQLCVESGLGKGTTFILTLPL"
     CDS             complement(16507..17199)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 180.6; E-value: 5.5e-55)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_174"
                     /transl_table=11
                     /translation="MNRILVIDDDRELCALIRHTVLQESIEAECCHFGRVGLEKLKSNE
                     YQLIILDVMMPGFDGFHTLEQIRKESCIPVLMFTAKNDSFSKVRGLRNGADDYMTKPFV
                     MEELLARIISLIRRYTMFNRNGNEAKTLNYDGLIIDLDTRSFTTEKGTFELPPKEFDLL
                     LFCAKNQGRIMTKQQIYEKVWGEPYVYDDSNIMSVISRLRKKLETDPGNPKYIQTVKGI
                     GYRFNKEV"
     PFAM_domain     complement(16522..16743)
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_174_0016"
                     /evalue="1.90E-23"
                     /label="ctg1_174"
                     /locus_tag="ctg1_174"
                     /protein_end="226"
                     /protein_start="152"
                     /score="82.4"
                     /tool="antismash"
                     /translation="FELPPKEFDLLLFCAKNQGRIMTKQQIYEKVWGEPYVYDDSNIMS
                     VISRLRKKLETDPGNPKYIQTVKGIGYRF"
     PFAM_domain     complement(16864..17190)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_174_0015"
                     /evalue="6.80E-24"
                     /label="ctg1_174"
                     /locus_tag="ctg1_174"
                     /protein_end="112"
                     /protein_start="3"
                     /score="84.3"
                     /tool="antismash"
                     /translation="ILVIDDDRELCALIRHTVLQESIEAECCHFGRVGLEKLKSNEYQL
                     IILDVMMPGFDGFHTLEQIRKESCIPVLMFTAKNDSFSKVRGLRNGADDYMTKPFVMEE
                     LLARI"
     CDS             17467..18507
                     /locus_tag="ctg1_175"
                     /transl_table=11
                     /translation="MNLFKKFISENWLGLFICFIIALPSWTLGKKFPVIGGPMIAIITG
                     MIIALFWNDKNEAEKGIKFTSKYILQTAVVFLGFGLNLNVILQTGRQSLPIILCTISTS
                     LIIAFILHKIMRISGNISTLIGVGSSICGGSAIAAAAPVIDADDDEVAQAISVIFFFNV
                     LAALLFPILGKMIGFDTLTGEAFGIFSGTAINDTSSVTAAASTWDSMWNLGTQTLDKAV
                     TVKLTRTLAIIPITLVLGIIKSRTSYEEDMDFDLMKSFPVFIIYFIIASVITTVALYIG
                     IPSNIFAPLKDFSKFCIIMAMGAIGLNSNIIKLVKSGGKPIILGGICWMGITFASLIMQ
                     HILKIW"
     PFAM_domain     17506..18438
                     /aSDomain="Cons_hypoth698"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03601.16"
                     /description="Conserved hypothetical protein 698"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_175_0017"
                     /evalue="1.50E-74"
                     /label="ctg1_175"
                     /locus_tag="ctg1_175"
                     /protein_end="324"
                     /protein_start="13"
                     /score="250.8"
                     /tool="antismash"
                     /translation="GLFICFIIALPSWTLGKKFPVIGGPMIAIITGMIIALFWNDKNEA
                     EKGIKFTSKYILQTAVVFLGFGLNLNVILQTGRQSLPIILCTISTSLIIAFILHKIMRI
                     SGNISTLIGVGSSICGGSAIAAAAPVIDADDDEVAQAISVIFFFNVLAALLFPILGKMI
                     GFDTLTGEAFGIFSGTAINDTSSVTAAASTWDSMWNLGTQTLDKAVTVKLTRTLAIIPI
                     TLVLGIIKSRTSYEEDMDFDLMKSFPVFIIYFIIASVITTVALYIGIPSNIFAPLKDFS
                     KFCIIMAMGAIGLNSNIIKLVKSGGKPIIL"
     CDS             complement(18741..19370)
                     /locus_tag="ctg1_176"
                     /transl_table=11
                     /translation="MSKMRKEYDPNKVKQRKRRPIVYIICEGKETETLYFKHFRSRNCL
                     VDIIPIPSKHKAAEHLVRHAKSLISQADYYPKDGDRLWCVFDCDDNKDSELQAAISYAE
                     KHGYKIAYSNPAFEYWYLLHFEKRNGYLKDSSTVSDILKNKGYLENYGKSVDVFEELQE
                     HQPKAIQYAKERVERLTGDQVAVICRDSNPVTTVYELVEFLNSKRT"
     PFAM_domain     complement(18759..19304)
                     /aSDomain="RloB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13707.8"
                     /description="RloB-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_176_0018"
                     /evalue="3.00E-37"
                     /label="ctg1_176"
                     /locus_tag="ctg1_176"
                     /protein_end="204"
                     /protein_start="22"
                     /score="128.8"
                     /tool="antismash"
                     /translation="YIICEGKETETLYFKHFRSRNCLVDIIPIPSKHKAAEHLVRHAKS
                     LISQADYYPKDGDRLWCVFDCDDNKDSELQAAISYAEKHGYKIAYSNPAFEYWYLLHFE
                     KRNGYLKDSSTVSDILKNKGYLENYGKSVDVFEELQEHQPKAIQYAKERVERLTGDQVA
                     VICRDSNPVTTVYELVEFL"
ORIGIN
        1 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
       61 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nntaccttaa agatgcttct
      601 ataatttcct gtggatccca ctatagtatg caattaaaaa acactgaaac ttgaaccttt
      661 caaatctcag tgtttttata tttagccttc tttcctcaac gacacaaact catagggcga
      721 aagtgtaagc cttccctctt tatactttaa gccgtcataa ttgcctaaaa cttttttaat
      781 tgtatattat aaacttgtca attctcaaaa atttgattaa aatatattta ttatcaatat
      841 aaataacttc aaagcattat aatattaatt gtatttaatt tattcttccg gagttattta
      901 actaactacg acaccacact aatacctaag ataatcatgt tcttatacac tacttattat
      961 atataacaag aactgtagaa taaacaacaa ggtgataaat atttatgggt gaagcaagca
     1021 gaaaaatagg aagtctgatt cgtcaattca gacaatccaa agcactgacc attgaagaat
     1081 tggctgaaag aattaataaa agcagggcaa ctttgtcaaa atatgaaaaa ggagatattg
     1141 tgttggatgt agataccctc tatgatattt ctgacgctct cggcattcaa gcggagcaac
     1201 ttttatacag aaaaaacaaa gaattttctt ttaacaataa aagaataaat cccggttttt
     1261 tccaaaatat tgagcaattc tatgcatatt tttatgatgg tcgcaataaa aaaataaatc
     1321 gttccgtcat tgacattatt cgtaatagcg acgttaacag ctatgaagtt gctatgtata
     1381 tgaactgttc cgatttgaat aattatcata aatcagaaaa tacctattgg ggatttatgg
     1441 agcactatga taccatgact ttactggagg taaccaacca ggatactcca actgaaaaag
     1501 ccagcataca aattttagct tcttttttag atgccgaagt taaatgggga ctttggaacg
     1561 gagtttccag ccgtccttta atgcctgttg ccttaaaaat gcttttttca aaaaaggctc
     1621 ttaaagagga taaagagctg gttcaacttc taaaggtaag taaagaagat tatcaaaatt
     1681 taaaatacta taattttttc tgtgttttct aatttatagt tttaaattta tgcattctct
     1741 tagctcggta gcggaatttc tcacatactg taatttcctt atacctccct tgccgtaata
     1801 tcggcagggg ggattaaaaa ttccccctaa aaaatcatat cttattttta tattcttcaa
     1861 tggatttgca gattctctca agtcctgtct ttattattgc ttgtggcatc gcaaggttca
     1921 aacgaatata tccatccgca tttcctacaa aaaggctgtt tcctccctct aaaagtactc
     1981 ctgcattatt cgcaaaaaat ccgggaaggt cttttacatc cggtaataca gctgataaat
     2041 caacccaagc cagataagtt gcctcggaga ttcccattac ggcctccgga agatttgtac
     2101 tcagatattc ctttacaaac tcaaaatttt tgtctaagta tatttttaac tcctcatgcc
     2161 attcaccacc tcggtcataa gccgcctttg ccgccacaag agacatcggg tttaccattc
     2221 cgaaaagttt atcacgattt ttaaaaattt ctctaagctg cggatccctt attataatat
     2281 ttgaaaatgc aagccctgca agattgaagg ttttacttgg tgccatacat gtaataagtt
     2341 taggataatt atcaagcacc ttagccatcg ggatatgttg cttgccctgc ctgattaaat
     2401 cacaatgaat ctcatcagat ataacccaaa gattatattg catcataatt tctccgcaac
     2461 gcctcagttc ttcctctgtc cacattcttc ctgtcggatt atgggggtta caccaaaata
     2521 ctaatttaca ggcaggatct gcacattgtt tttcaaaatt ttcatagtcc aatacaaatc
     2581 tgccattttt atcttttttt aaaggagact gaagcacttc cactcctgaa tactctgccg
     2641 catggagaaa ataaccataa gaaggggtat taacaagtac cttctcattt ttggtcaata
     2701 aagtttccac cagttgatac attgccggta taatccccgg tgaaaagcag agctcatctt
     2761 taggaaatga ccacttataa tgatcttcac accacttttt aaatgactga tagtagctgt
     2821 catcatatac tcctgtatac ccgaatattt ttctgtcgat tctttctctc aatgcctcaa
     2881 gaatcggtgc agcaacagca aattccatat cagccaccca catacgcaca aattcttcat
     2941 ctttatacgg aaatttcttt tcaggctccg catgaaaaat atatcctcta aaaccgtctg
     3001 tattcaaaca attggtattt ctccgatcaa ttatttcatc aaagttatac atttaaacct
     3061 ccttattctg cccaattatt aatatttccc gaaacaatac ttgtatgata ataggtgtaa
     3121 aaacaacatc tgctctgcta ttcctcaagt aatgcttctt ttacaatttc ttctctgcgc
     3181 ttatccaggc tctcttttga aacagctccc tttttcaaag caattgcaga aaatagaagc
     3241 ggaatcaata ttatagcggc agctgtaatc atatcataaa ttgtaagccc gccaaataat
     3301 gtggaagcta ctataagagc acagattcct cctaaaatac agcaaatgtc atatattacc
     3361 gccgggcact ttatagacct tttctcaaat tgtttaggat attttctcgg tatagtaata
     3421 caatacacat tcaagaatgc attaatcagc atactgggaa tcatcagcat ggaaattgca
     3481 ttatttacgc tcattccggt taatatggga accaatgcaa taatataaac tatcaaaaag
     3541 cagtatttag gatatccgtc agcagttttt tctttaaaga tggcaggcaa ccatccatca
     3601 tcggccatat gtgcaatagg ttctctaatc atggctaata cagcaagaaa cgaagaaact
     3661 attgcgcaaa ctcctccgcc taacacaaaa taagcaaaca tccccttagg cataattacc
     3721 gatgcagtaa ctgacaaatt ttgccctgca acctcatcat atggaaggac tccggcagcg
     3781 gcaaatgaca tcaatccata tattatagaa accacaacac atgttattaa aatacccatg
     3841 ggaattgttc gcttaggatt ttttgttatg ggaataactc ccaccggccc cattgtagtt
     3901 ccttgacatg cccatcccat gattgcaatt gcatttataa ctccaaaaaa cccgttatga
     3961 aaaaatccgc catcataact catatcaaaa aagttattta tatccacttt ggggattcca
     4021 agtataacaa aaagcattaa tgctcctatt aaaaatatcg ttgcagcatt ttgaaataat
     4081 gcaacaattc tatttccttt aattgagagc agaaaaaaca aagttaatat agcagcactt
     4141 gtcagtttcc catgttcacc aagtacaggc caaagactgc taagataact tgtcagtcct
     4201 aaagcatatc cggtaaatcc gaatgcccaa atcacattcg tccagcctcc atagccgatt
     4261 aaaataggtg gaagaagcat acccttcatg ctgtagtctc ctccatttac aataaagata
     4321 cctgaaagtg ccagattata ccagtaagcc aacagcatat aaaatacaca tataacagtc
     4381 atcggaagaa ttgaacgacc tgtactggca atagctgtgc ccaatgtaat aaaaattcct
     4441 gaacccacgg caccgccaac tcccagaccg acaacattcc atagtccaat ttttttagaa
     4501 gtttccttat tcaattttgc ctccttatgg aaatgaaaaa tcatatctct aagaatgtac
     4561 tgcgcagcac tctttgtaat aaacattata tatgtgaaaa aaacttattg caaaaagagt
     4621 aaaatctctt taaacgaaat tttttcttta aaaaattctt ctcatgagaa aaaaactata
     4681 ttttattaaa taaaatcaag aaagacaaaa tatccagaaa cttatgtaaa aaaatcaatt
     4741 tataataaat aaatatggcc gctcaactcg caaagactat ataatcatag taaccctaca
     4801 tgcacatcca atgtgcacca cccacggcaa aagtgggggt atgggggcac acttgaattc
     4861 aagctgcctg acggcagcag gactttcaaa gtaataagct tgtgatatct aatcaattcc
     4921 ctcctcatta tagtacaatt cggcatttcc catgccaaca ccgtttcccc taatttttta
     4981 aaatcatctc acaaacaaat cctcccatct ccccctcatg aaaggatatt ttccatttat
     5041 gacggcttgc cacctgcttt actattttta atcccagccc gtgatttcct tcacttcttt
     5101 ccgtttcata acttttttta ttcagctttt ttaaaagctc tcttgaaact cccgctccat
     5161 tatcttccac actcagcact atggcgtttt tttcattttt atataatttg atttgaatat
     5221 tgcagccctt gggattatgc tttattgaat tatttaaaag gttaataatt gccctttctg
     5281 taaagtcttc gtttattaag aagcactctt tttgaagaga ctcgtcaata tccaattcaa
     5341 agctaaaaac atcctcttcc aatgcattta aaatctgagt gacacacttt ctcagtaatg
     5401 tacttatttg gatattcttt ttttcaaact ttacacttcc gtagtccagt ttatttaaaa
     5461 aatttaaatt ctccacaagt gtacgacatc ttatcccctg cttttcaata atttcagccc
     5521 tttttcttac ttcataatct ttgctttctc ccattatcat tccggcattt cccagtatta
     5581 tagctaaggg agtgcgaata tcatgggaga ctccggcaat ccattacacc cttcttcttc
     5641 cctttgtctg atttgccttc tgtaaagtcc cagggaaatt ataattaaaa gcaccacatt
     5701 ccccaaaata agaaacggtg tcatcttaat tgacagcagc aaagaatcct cataatattc
     5761 caatgtatat ttccaaatat ttttattcct atatcccacc accaaaagcc ccggactcac
     5821 tacataggta tgtacttgat aatcattcaa ataatacctt gtaaaccttg ccacatcctg
     5881 aagtgtatat tccttttcaa gttcctttgg cagatcttca ctccataaaa tatttcctga
     5941 attatccaaa agcattgcaa actctcctct ttccctaagg ctttccaccg cctcatctga
     6001 gagcttatac tttccctcct caaataaaag attttccatt atattgacct taggataata
     6061 taatgaaaga gcgcttttat acataacaat gccgtaaaga attaaatcta taaataataa
     6121 tgcaaatatt gtcattatta ccaggataat taatcctaga ttattcatgg taactccatg
     6181 aaagtggctg aaagacatat tattactata ttttaactaa atattgcttt tcacttatca
     6241 agtgaataaa aaaagagcgt ccatttgtgg taaaattaag gtgctttaaa cttaacaaaa
     6301 tcacacaaag gagcccttta tgagtattgt aaacacctta tcacttgaaa gcaatagaaa
     6361 aattaaaatt aatttcgatg gaggggattt atcctccgat gctgccttac ttcttataaa
     6421 agaattcgta agtaaacttg gtattgataa acttttcagt caatcattta agaccaatga
     6481 ttctgcatta tttcgttatc acactgataa agaaaacctt tttcagatga tatatatgat
     6541 cattgcaggt tattttgaag atgattcttc agatgaactt acaaatgatc ctgtgtttaa
     6601 agcagtgctg aataaagaca ctttaatcac aaccgaccat ttcaagattt tataatcgaa
     6661 tggatgagga ttctctgaaa cagttccttt ctataaacta aacccttcga aagaaagttt
     6721 atagcattca gatgccggaa gctatcattt tagatttgga ctcaacactt cttaatgcct
     6781 atggcaaaca ggaaggcaga gcatttaact tccactatca aagtaacggt taccatctac
     6841 ttgtttgcta tgatggaatc acaggagatt tgattaaaat tcagcttcgc gacgggactc
     6901 agtattcaag cacaggagtt gtggactttc tgcagcctat acttgatgaa taccttgaag
     6961 attttccgga aattaaactt ttacctcgtg gagatagtgg ctttgcaaca ccaggtttat
     7021 ataaacagta tgaagaaaac ggtaccggct atgtaatttg tttgaaagaa aatgctatac
     7081 ttcgtgataa ggcatcatat cttgtagatg aaatcacaaa aaacaacaaa gtagattatg
     7141 ctgttgttta tggtgaactc atgtatcagg caagtccttg gccttatgaa agacgcgctg
     7201 tctgtaaagt tgaaaaaact gaaaaccaaa tgacttacat gtatacattc attgttacaa
     7261 atatggagtc atcccctgaa tatcttatca agttctattg caaaagaggc ttgatagaaa
     7321 acttcataaa ggaaagtaaa acaggttttg actttgcttc tgtcagcagt catacaagaa
     7381 ttgtaaatgc caacaggctt caactacatg cacttgctta taacatattt aattggttta
     7441 gacgattggc attatctgta aatatgagaa aacaacgtat tgatactgtt cgtctaaaac
     7501 cgcttaagat tgctgcaaaa gtaattcgtt cagcaaggta tgtaacattc aagctgtgta
     7561 gcagttgccc atataaggat gagttctata agcccctatc caatatcagc aagctattta
     7621 tacagcttga ataacaacta ataatgaacc ttgagagctt aataactact caaaaactct
     7681 acctagggga agtctgccca tttttaggtg tattaagtca gttatagcgt catgggttaa
     7741 gtttaaaaat taatagcacg gtaattaatt taaatattac accgtgaata attcaggcta
     7801 agtaaacaat atcaggtctt ttaatggctt tttatagatt tactagacct tgaaatatat
     7861 aaaatagtgc ctaaagtata tagcactgtt ttatatacaa gaccttaatg aacacttaaa
     7921 acaattttag tattataaaa tatgcttata ataaatctaa tgtaaccaat aaagaccggt
     7981 agaagcatta tttgtcataa ttccctgtac cctttgtgca aaaacctcat ctttagtaag
     8041 taaatcattc catttaacta aatttctatc ttttttattg ttatgtaaat ccattttctt
     8101 atgtgcaact ttactatacc catctgactc atttccagaa gtattcctgt cttcaggtgc
     8161 agttgcatat gccgcagccc agcctttatt tattcgtgca gtcattaaag cattccagta
     8221 tgcatgtcta aaagcgtctg tattatcacc taaaccatta tatccatata actctgccgt
     8281 ttttgcaact gcattgtttg ccaattcttt agtaattgca gcatttacag ggttagttgc
     8341 tattaatatt ttttcagata aggtaagtgc agtccatgac tcataccacc ctgctggttg
     8401 tgctgtatta caatacatat cctcatattc ttttaagatt tgctctggcg ataaatcagg
     8461 attgctatct tttatttcct ttattttatc aacaaagtca tcataatctg ctggaaagcc
     8521 aagtgcatca atatcttcaa taactgaata tgaatctcca acttgtaatg attggtactc
     8581 tgtacttgtg ttttcttcat cagcataaat attattagtt attgggattg caatcataaa
     8641 acaacttaaa gccgttacca taattttgct tatatttttc atataatcat tattcctttc
     8701 aatattaatt ttaaaattat tatctaacaa aatatttatc atagataaaa tttgctttgt
     8761 ctataatcta ctttctccat gatatacttc ttctgcagta tcactattga catcaactat
     8821 tactttatca acattctcct taaaattagg gatattaaca aatatttctg aagatacttc
     8881 atcatcgctg taaactggaa tagcctttaa attaattttt aatatactgt tctcatatgt
     8941 tatcacattt actttgagct ttgaataaaa gataatatct ccataagttc gataataaaa
     9001 attgtaatta tcactattat ttataatata atacctatta tcaataagtt gcttaatatc
     9061 tacttcaaat ttattttgtt cataatacaa aatagaacca ttattttgtg ttttttcaca
     9121 acctgataaa tataaagcac ttaataacaa aattaaaaat aaactattct tatagaatat
     9181 cataattaca cccactaatc ctaaattatt catagcatag ctatgtctgc ggctgaaagc
     9241 cacataatta ctgcatttac aaaactttct tactttcacc taaaaagtga atagaaaaaa
     9301 gacctctttc ttggtaaaat taaggtgtca aatcaaaaca atgccaagga aaggaagtcc
     9361 tcttatgtca attttaaaca ctatttcact tgaaagcaac aagaaaatta aaataaattt
     9421 taacggtgga aatctccctt ctgatgtagg gctgctcctc atcaaagaat ttgctgcaaa
     9481 ggtaggtctt ataaagcttg tgaaaaagct cttcaaaacc aatgaccata caaacagccg
     9541 tattcataca gattctgata accttatgca gatgctctac caaattatag cagcctattt
     9601 tgaggatgat tgtgcagatg aactgactaa tgacccggta ttaacatcta ttttggaaaa
     9661 agaagccttg gcttctcaac ctacactatc tcgtttttgg aatagaatgg acaacgacac
     9721 tcttacacag cttgattcta taaatgcaaa aatgcgtgat attgtctatt ctattaaggc
     9781 tccggagcac atgttttttg accttgattc tacactgctt aacacctacg gcaagcagga
     9841 aggcgaaggt tttaactttc attatcaggc tcacggttat catccactac agctcttatc
     9901 atttgtgtta atccaaatgc ataaatttcc ttatcatctt ccagaaaaat attattttcg
     9961 atcacatatt gtatgatttt tttgatagcc tttccataac ttaaaattta cgcaactttt
    10021 tcactttgtc aggtaactca ggctgatgat aaataaaagc acacgctgaa tttgcattaa
    10081 aaagtgcaaa tacaaatgag catagagcaa tgcctttact tattagcaat aaatactttt
    10141 tcatagttaa atcctccttt caatattctt ttaataagtt acgctttgga ttatactaaa
    10201 taatgatgta ctgtgcgaaa aatgtaatga actgtatggt tatttgtaat gaaatgcatt
    10261 ttttataaaa ataataatcc ccatactata aatattttta tttacacaaa aagcattaat
    10321 ataccgcaaa tatctccatc caaataatgc atcaatgtga ataaaatgtc tttctatgaa
    10381 atagttgggc tgtatgttga tataaatatt aaagggaagt aaattcataa aaattcaaag
    10441 ttcaaaaagt tactatatac catgatattc atatatttat taataggaaa aagggaaggt
    10501 tacccttccc atatcttaaa catcattcta aaacttaggc aaaacttgac atactctaat
    10561 attctttaat tataccctct ttagatttcg gcaatatagc tacatttatt ttgtttgtaa
    10621 aatcacctat tccattttct ataagcatca cgaactttct gaatgattct tgtgttaata
    10681 aattatttct cttgaaagcc tttctcattg atttattcat tttatacaat caataattat
    10741 aatttgattt ccttggaaat atcctttatc tttttctttt atcagcaata taaaatcact
    10801 aaaactacaa atagattatc ttcataatct atttgcataa tgccattata tctttctgct
    10861 acttccctta cgctttctaa tccaatgcca tgaccttgtt tttccttttt ggttgtctga
    10921 agttttcctt gggatttgac tatattttta tatgaatttt ctatttgtaa aattagcctc
    10981 ccttttttat atttcaaatt tatttttaat tcttttctat ccgactcttt tacagctctg
    11041 actgcattat ccaacaaatt tccaagcgcc actgtcatat ccacatctga tatttctaac
    11101 ttcttaggaa tacaaacatc aatatataaa tttatatcat taatatttct caatttgtaa
    11161 tttataatac tatccactac taaatttccg gatttacaca cttcttcttt tttatctatt
    11221 tttgataata aagtatccaa gtaatctcgg tatgaatcta tttctccttt ttcatataac
    11281 gatttcaaca taaataaatg attttgtata tcatgtctaa tcaaagagat attttcatta
    11341 ttggcttgta tcatttttag ttgttgtaag tatgcttcat cttgcttttg taaaagaagc
    11401 tttttatttt tctcctgcat tatggaaaca acatggttat ataattgaaa actcactata
    11461 ttgattatag caatggatag cagtacaatt aatatatgca gttgttcaga gcctgttgct
    11521 atattaagaa ataaaatcat tacaaccaaa cttgcaaccg gtatacttac aactcctatc
    11581 caatatagag gagatatttc tcctgatttt tttatattga attttctttc agaaagaatc
    11641 aatgctacta tatacaccaa tactttcaca caaataataa gataaacaga atgcaactcc
    11701 tgtactttaa aaatgaatat ctttttatat tcaaacaaag acataaccat tatttcaata
    11761 ccaaagataa tcaaataaac atataccgta gctgttatat ggcgctttaa tgttccgcta
    11821 taattgagtg ttatagcaaa aatacttatt atgttaaatg aaagaagaac tactggaacc
    11881 ggaaagaaag taaaaatcag aacactcaaa atataatata taacatatga cagtacctca
    11941 acacatttat agatgttttc tctttcaaaa aatatagata taagtttaaa aattgaaaaa
    12001 gttcccaata tgttactgac taaaaataca ctatgtacta aactcactat tataatcctt
    12061 tcctctcaaa catcatctgt aactttctta tttcttttct tttactcctg cttatcggga
    12121 taatatctcc atttgacatt ataagttctt catatttaaa gcaagctata agctcataat
    12181 ttacaagata acttctatgt ggatatatga aaaaatccgg taacacttta ctcaattctt
    12241 ggatattatc ataaaatgtg tattgcattt tgcaacttac taaactgatt tctctgcctt
    12301 tactttcaaa gtacaatatg tctttatatg gcacttttac tgtgttcctg agatttttaa
    12361 attcaaagat tttattttcc tttccagaga ttttaattgc taattttatg tcatttagaa
    12421 gttttgaaac atcaattggc ttttgaagaa aatgcaaagg ttgtacatca aacagttgcc
    12481 tgtcataatt attcttagac gaaatatata ctatttgagt tatataatcg tccatttcat
    12541 ctctaataat atgccctatc tccacaccat ttatcttacc tccaagttca atatccaaaa
    12601 aaatcaaatc atatagattc ccttccccta tatcggatat taaggcatct ccactataaa
    12661 atatatcaac gctaatattc tcatgtaaaa ctccctttgc tttacttaaa ataatttctt
    12721 taagttcatc acatgtagcc ttaatatcat cacaaacagc aatcttaaac ataataactc
    12781 caattccgcc gccaaacctt ggcacaaagt ttcttaagaa tcttcataca ttatatagat
    12841 tatatcacag ccaaaatcaa tgatatagat aaacaaatta attctctaat cctttgttaa
    12901 aaagtgttgc agtacatcag aatagctgta aaaataaaaa gtcacagaat tagaattagg
    12961 attttaattt attctgtgac ttttttcagc tatgtttact tgtgttagca cttattgtta
    13021 tcccatcccc ttcgttgtct ctttttgttt tgtactgtct tttaaaacag atgacattat
    13081 cttatcataa tccggcgtat agaaaatcaa tattgctgta accaatatca tcaacattaa
    13141 tgatatacaa ccaattgccg gattgtaagc tccctgtgca taactgataa ttccaagccc
    13201 cgccgtaaca ggatatacat ctgtcaaatg tctccctgct gcaaaaattc cgcaaagccc
    13261 ataaaagaaa gccaatccga caccgacata aaaacctcca cgctttctgc tgaaaaatgc
    13321 aatcaatgga gaaaccgcaa taaaattaaa aacggctatc aaagaaattt gaatacatga
    13381 aactccgatt acctcagacc ccatttcttt acaagaaaga aaaaactttg ctgctgccag
    13441 tgtacagata aagctgaata atccaagtat tgcagatatt actcctacac agatcatctt
    13501 ggcaagcagt aatctgcgca tagaaacagg aactgtcatg atatttttca atgtatcatc
    13561 tgtgtattca tggtcaatca tataccctcc aatcaatgtg attgaaaaag gaaaggaaat
    13621 actaaaatta ttccagatta cactattaaa aaattcgtta taggagagag tttttacacc
    13681 ttcaaaattt tgaaatacag atataacaac agcaaagata acagccacaa taccaatcca
    13741 cataatattg tatctcttca gtttaataaa ttcacagccg ataagattca ttattttcat
    13801 acctcctata tttctgtacg tttataactg aacagggaca gtagagtaaa ggcaattcca
    13861 tatgcaacca gaagcccgaa agcaaccggt gttgataatg tgtatggaag tatataggaa
    13921 agtgcttgct ccacaggaac gatacccaaa taccacttgc ctgtaataca aatcggtaaa
    13981 gcgaatgtga gcctatctaa caccgatcct ctgcctattg tctgcaccgt cacaaatcca
    14041 agtacagcat aaattaatac aataatgatt gagaaaactt tacttttatt gcaaacaatt
    14101 ataatcgcta taaccggtac ggtagccaaa aaaacaaaaa ttccaagccc tattgaaact
    14161 gaaaataaaa acggaacatc tgatatttta ccaataatca gacctccgat aagtgaagct
    14221 gcataagccg ccaatgtata tattaatgac aaaagaaaca ataccgtaag tttagttaaa
    14281 aagatatttg tctttgatac cggaatgacc agcagatttt ttaaagtatc actgtcctgt
    14341 tccatagaaa aaagtatgat tgcaacgatt ccaagcacac atggcaaaaa cagaatatca
    14401 tcaaacatta caacagcccg aaacagctga ataaatgact gcccgtcttt tgccatagca
    14461 ataatcaaag gagtcggaaa taaacaggcc gcagctatgg taagcttaat aaatctcttc
    14521 cgtctcaatt ttttaaattc acatcccaca agtttaagca attccctcac cccctgttac
    14581 acgtttaaaa taatcttcca gtgtctcctc acaagtatgg gcttcggaca cctccaatcc
    14641 ggtttctaca tatgcggcaa caatttttcc cacgggtaaa tcaaggttat acaggttgag
    14701 attgtgatcg tcatgaacaa gaaaatgtgt ctcattaaat gttttttcca aaaccattgc
    14761 ggcttgtgcc gaatccgaaa cagtgaaatg aatgtggcga ctgctctttt gttcaagttc
    14821 tgcaaaagtt tcttcttcca gcagtacgcc acggtctatg ataccgatat catccgcaag
    14881 caaggcgatt tccgaaagga tatggctgga aagcagaatt gtcttacccc tcttgttgca
    14941 aagttctctg atgaatttcc gtacctcagc aatcccgatt ggatcaagcc cgttgatcgg
    15001 ctcgtccagt atcaaaagct ccggatcatg catgactgca agtgcaattg caagacgctg
    15061 tttcattccc agtgagtatt gagaaaacaa ctttttatct ttatacggca ggccgactaa
    15121 attcagtgca tcctgaatag agtggttgtt gggaacacca cgcagtattg caaaaatact
    15181 caggttttct gtcccggtca gattcggata aaatccggga gactcgatca tgcttcctat
    15241 acgtggaagc actttatttt cattaccatg cagaggctct ccccataaca ggacttcccc
    15301 aatagtaggt tttgtcagac ccaaaagcat tttcattgtg gttgttttac ccgcaccgtt
    15361 tctgcctaaa agaccgtaaa cccgtccttt tttcacatga atattcaaat cggccacgct
    15421 tttttgtgtg ccgtactgtt ttgtcaaatg tcttgtttca ataatatata ggctcataca
    15481 aaaaacctcc tttgtattac tcatattgta gcatgccaac cttgcattaa ccttacaatt
    15541 taaaaaacag ccggccacat agccgactga atataataca ttattttaaa agaggcaagg
    15601 tcagaataaa tgtcgtacct ttccccaagc cgctttcaac acatagctgc cctcccatct
    15661 tttctgccaa ctggtacgca atagacagac caagcccgct gcttttattg ctcctgctct
    15721 tgtcacattt ataaaggcgt gaaaaaatat gtttaagctc ctcttttcca atgccgatgc
    15781 cgttatcttc tactgacaat ctcattacac cctcatgttt tgtgaaaagc acatctattc
    15841 tatctgccat gctgtgtgta ataacatttt gcaacagatt atttatgatc cgcaagtaac
    15901 tgtcctgatt aagattaact gtgactgcct gatccggtat ctctatagag tattcgatac
    15961 cctgctcctc caaaagaggt atccagtcaa tcagaatatt gcgggtcagt tctgccgcct
    16021 ccacactttg tatctccata gcaaattcat ctgaattgag cttaaaccaa tcaaacaaaa
    16081 catcaatata tcctttgagg tcgtaggctt tatgtcttga tatttcgatg tattcctcac
    16141 gttcactacc ggtaacactg cctttatgta ccgcatccaa atatccgatc agtgttgtca
    16201 aaggtgtcct cacatcatgt gaaaggcttg tcataagttg tttgttcatt tcatctgtct
    16261 gctgaaatac tgctattttg tcctcataag ctcttataat gtcattgatt tcatatacaa
    16321 gaggagaaag cagctgaccg ggataggcaa gaatgcggcg gtttccgttt ccgtttctca
    16381 catcaagcaa agcttttgaa atctccccaa tttgctgtcg ttccctgtgc agaataagta
    16441 cggaataaat aatgacaagc atggtaacga atgtaagaac aattattaaa acttccatag
    16501 tagagatcac acctccttat tgaaacggta gccgataccc tttaccgtct gtatgtactt
    16561 cggatttccg ggatccgtct ccagcttctt acgcaggcga ctgataacag acatgatatt
    16621 gctgtcatca taaacataag gttcacccca cactttttca taaatttgct gctttgtcat
    16681 aattcgtccc tgattttttg cacaaaacaa aagcaaatca aactctttgg gaggaagttc
    16741 aaaagtcccc ttttcagttg tgaaagatct tgtatcaagg tcaataataa ggccgtcata
    16801 gttaagtgtt tttgcctcgt tcccgtttcg gttaaacatt gtataacgcc gaatcaacga
    16861 gataatgcgt gcaagcagtt cctccataac aaatggtttt gtcatataat catctgctcc
    16921 gttacgcagt ccgcgcactt ttgaaaagct gtcatttttt gctgtaaaca tcagaacagg
    16981 tatgcaactc tcttttctaa tctgttccaa tgtgtgaaac ccgtcaaatc ccggcatcat
    17041 aacgtccaaa ataataagct gatattcatt tgactttagt ttttctaaac cgacccgtcc
    17101 aaagtggcaa cattccgcct ctatactttc ctgtaaaact gtatgcctaa tcagagcaca
    17161 cagttcacgg tcatcatcaa taaccaaaat cctgttcatt cccttatctc cgtccttaat
    17221 tctattatat tttctgctcc accctcatct tttccgatgt atgttatttt tttacaagtc
    17281 cgttatttac attttcataa aactgtctat caatcaaaac cgacggtgtt acaatttaac
    17341 tataccacaa caatccctat gataagaaaa tgtaaatact attttaaata tttttttatt
    17401 ctaattttcc ctcccctatt gtactataat cgtactgtta aaatatcctg aaaggattga
    17461 tcataaatga atttatttaa aaaatttata tcagagaact ggctcggtct gtttatatgt
    17521 tttattattg ctctaccctc atggactctt ggtaagaagt ttccggtgat aggcggtcca
    17581 atgattgcta tcattacagg catgattatt gccctttttt ggaatgataa gaatgaggcg
    17641 gaaaagggaa taaaattcac ttcaaaatat attttgcaga ccgcagttgt tttcttgggc
    17701 tttggtctta atctaaatgt tatacttcaa accggcaggc agtcattgcc cattatttta
    17761 tgtaccatat ccacatcatt gattattgcc tttattcttc acaaaataat gagaatatca
    17821 ggcaatatat ccacacttat aggagtgggt tcctcaatat gcggcggttc cgccatagct
    17881 gccgctgctc ctgtgattga tgcggatgat gatgaggtgg cacaggcaat atcagttatt
    17941 ttctttttta atgtgctggc agcactgctt ttcccgatat tgggaaaaat gataggtttt
    18001 gatactttaa caggtgaggc ctttggaatc ttttccggta ccgcaataaa tgatacttcc
    18061 tctgtaactg ctgccgcttc tacatgggac agtatgtgga atcttggtac acagactctt
    18121 gataaagccg ttacggtaaa actgacaaga actcttgcta ttatacctat aactttagta
    18181 cttggaataa taaaatctcg tacctcatat gaggaagata tggattttga tctgatgaaa
    18241 tcatttccgg tatttataat atattttatt attgcatctg ttattactac tgttgcctta
    18301 tatatcggca taccttcaaa tatctttgct ccattgaaag actttagtaa attctgcatt
    18361 atcatggcaa tgggagcaat agggctcaac agcaatataa tcaagctggt aaaatcaggc
    18421 ggaaagccta ttattcttgg aggaatatgt tggatgggta ttacttttgc aagccttatt
    18481 atgcaacata tacttaaaat atggtaaacc tctattttct catactttac tataccaaaa
    18541 aattaaactg actctatctt aaaaatacct atgcaactgt acagtcaagc aacctgttat
    18601 acttgactgt acagcaccac attaatttga tatcgcttta atttgatgaa ttaaagcgat
    18661 atcaaaaaaa gtctgtcatg aaatttttat cattgaattg acagctttct gtcattatat
    18721 acacttctac aatggtgtat ttatgttctt ttactattta aaaactcaac cagctcatag
    18781 actgttgtta ccggattact atcccgacag atcacagcaa cctgatctcc tgttaatcgc
    18841 tccactcgtt cttttgcgta ctgaatagct ttcggctgat gttcctgcaa ttcttcaaaa
    18901 acatccacgc tttttccgta gttctccaga taccctttat ttttcaagat atcacttact
    18961 gtagaggaat ctttcaaata tccattccgt ttttcaaagt ggagcaaata ccaatattca
    19021 aatgccggat tggaatatgc gattttgtac ccatgtttct ccgcatagga aattgcggct
    19081 tggagttcag agtctttatt atcatcacaa tcgaatacac accaaagccg atctccatct
    19141 tttggataat agtcagcttg agaaattaaa gattttgcat gtctaaccaa atgttccgct
    19201 gctttatgtt ttgacggaat tgggataata tccaccaggc agtttcgtga acgaaaatgt
    19261 ttgaaataaa gtgtctctgt ttcttttcct tcgcatatga tataaacaat cggtctacgc
    19321 ttacgctgct tcactttgtt cggatcgtac tcttttcgca tcttactcat caggtgtcac
    19381 ctccgataaa agggattgca ccaaaccgtc cccggagata acctttgcgt acattttctc
    19441 cttttcttgg agaaaatgat gccagagagt aaagctctgt tgcacaagtc ccatcgttct
    19501 tttcagcaaa ccaaatctga tctctacgga agaaattcaa atcaagtagc attacatcat
    19561 gtgttgtaaa aatcagctgc gttccctttg tattgataac cttatcctgc accatttcaa
    19621 tcagccttct ggttaaaaga ggatgcagac tatcttcaat ttcatcaaca actaaaagtg
    19681 tgccgttttc aagtgcctgc aaccacccgc caatgcggga aaaaaaatgt tgtgtaccga
    19741 cagattcctg ctccattaaa agccgaaagt attctgttgt accatcctcg ttaataattc
    19801 gatgtgttgt cataataacc gggatttcac cggaagtatt cttgattgta acatcggtaa
    19861 ttccaagatc cgcaagcaac aattctttta agatttgagc tttcttatcg tcaccaccgg
    19921 caatctgagc aacggtttct gaggtagcag gttcttcatc catcaggaat gtcaactttt
    19981 ccagaaacca ctgataagca ttttccgtct gaggcaggtt ccagtcatta gatgacacca
    20041 gatagagctt attatccggt gttcgattgc ttagagttac ctgttcattt acattttccc
    20101 ggaactcata cactccgttt tctcttgaaa aaattaatgc ttca
//
