LOCUS       NZ_CP120376.1           8968 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP120376.1 Pseudomonas nitroreducens strain L4 chromosome,
            complete genome.
ACCESSION   NZ_CP120376
VERSION     NZ_CP120376.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:48:45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2624444
            Orig. end    :: 2633412
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..345)
                     /locus_tag="ctg1_2400"
                     /transl_table=11
                     /translation="MSAMTLEGWCKTTAEQKPTPLEDIRFYLTDQDRLHLEQAEVYLQE
                     NGQREMMVDADLDTLDLHMPEGYGPLADCMFRVYLGGVEHRGQFHLVGHRASDGSLIYT
                     NAVLIDQLIN"
     protocluster    1..8968
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2628209:2629049](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3766..4605
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..8968
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8968
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(725..2053)
                     /locus_tag="ctg1_2401"
                     /transl_table=11
                     /translation="MKHLKRSAIVLAVSAAASQFAAAEPFVTDQADAKGLVEDAKLDVL
                     LRNQYYDHDGKNGFADNRDWTQGFLANFSSGYTQGTVGFGVDAFGYLGIKLDAGRGRAG
                     TGNLPVGNDGKPDDDYGKAGGALKVRISKTELKFGDMQPTAPVFAAGGTRLIPQTASGF
                     NLLSSEIEGLDLEAGHFTSGTSPVTTARDGGLWAAYAVRETSDVDFLGGKYAINDNLSV
                     SLYGSEFKDIWRQYYGNLNWVLPVADDQSLAFDFNIYRTNDEGRAEAGEISNTTWSLAA
                     AYSFLQAHTVTLAYQKVHGDTPFDYVGFGDDGAGATGDSVFLANSVQYSDFNGPGERSW
                     QVRYDLAMDTYGVPGLSFMARYINGTGIDGSHADADGAYAGLYGEDGSHHETDLEAKYV
                     VQGGPAKDLSFRLRQAFHRANADQGEADNNEMRLIVEYPLSIL"
     PFAM_domain     complement(731..1954)
                     /aSDomain="OprD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03573.15"
                     /description="outer membrane porin, OprD family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2401_0001"
                     /evalue="7.20E-152"
                     /label="ctg1_2401"
                     /locus_tag="ctg1_2401"
                     /protein_end="441"
                     /protein_start="33"
                     /score="506.1"
                     /tool="antismash"
                     /translation="KGLVEDAKLDVLLRNQYYDHDGKNGFADNRDWTQGFLANFSSGYT
                     QGTVGFGVDAFGYLGIKLDAGRGRAGTGNLPVGNDGKPDDDYGKAGGALKVRISKTELK
                     FGDMQPTAPVFAAGGTRLIPQTASGFNLLSSEIEGLDLEAGHFTSGTSPVTTARDGGLW
                     AAYAVRETSDVDFLGGKYAINDNLSVSLYGSEFKDIWRQYYGNLNWVLPVADDQSLAFD
                     FNIYRTNDEGRAEAGEISNTTWSLAAAYSFLQAHTVTLAYQKVHGDTPFDYVGFGDDGA
                     GATGDSVFLANSVQYSDFNGPGERSWQVRYDLAMDTYGVPGLSFMARYINGTGIDGSHA
                     DADGAYAGLYGEDGSHHETDLEAKYVVQGGPAKDLSFRLRQAFHRANADQGEADNNEMR
                     LIVEYPLSI"
     CDS             2504..2881
                     /locus_tag="ctg1_2402"
                     /transl_table=11
                     /translation="MTPTFIPDADPESISSDVAGFGGLLVSTQIPTLEDGSLELGDIKA
                     QSEATLRSLQLALEKAGSGLDHVLHLTIYLTSMADRAAFNEVYCSFFAKPYPVRAAVGI
                     AELAVEGMKVEVTAIAAKRAG"
     PFAM_domain     2573..2866
                     /aSDomain="Ribonuc_L-PSP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01042.23"
                     /description="Endoribonuclease L-PSP"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2402_0002"
                     /evalue="4.10E-22"
                     /label="ctg1_2402"
                     /locus_tag="ctg1_2402"
                     /protein_end="121"
                     /protein_start="23"
                     /score="78.5"
                     /tool="antismash"
                     /translation="LLVSTQIPTLEDGSLELGDIKAQSEATLRSLQLALEKAGSGLDHV
                     LHLTIYLTSMADRAAFNEVYCSFFAKPYPVRAAVGIAELAVEGMKVEVTAIAA"
     CDS             3190..3705
                     /locus_tag="ctg1_2403"
                     /transl_table=11
                     /translation="MTRLSKSQLGLIAVALAGGLNMASSAFAVEALPQGYQLASAAKAG
                     EGKCGEGKCGAAKQTKASQTEGKCGEGKCGADGAQAKATGAEGKCGEGKCGDASFARTD
                     ADHDGRVSRAELLAVAPKANAEFDAIDANHDGYLSEAEVYQFRKNQFDSNGKPFPADLY
                     SKLSQARN"
     PFAM_domain     3487..3546
                     /aSDomain="EF-hand_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13202.8"
                     /description="EF hand"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2403_0003"
                     /evalue="8.50E-03"
                     /label="ctg1_2403"
                     /locus_tag="ctg1_2403"
                     /protein_end="119"
                     /protein_start="99"
                     /score="15.6"
                     /tool="antismash"
                     /translation="FARTDADHDGRVSRAELLAV"
     PFAM_domain     3565..3627
                     /aSDomain="EF-hand_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13202.8"
                     /description="EF hand"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2403_0004"
                     /evalue="6.90E-04"
                     /label="ctg1_2403"
                     /locus_tag="ctg1_2403"
                     /protein_end="146"
                     /protein_start="125"
                     /score="19.1"
                     /tool="antismash"
                     /translation="EFDAIDANHDGYLSEAEVYQF"
     CDS             3766..4605
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2404"
                     /sec_met_domain="DUF692 (E-value: 7.2e-120, bitscore:
                     397.6, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSLNGAGLGLRRALLPDLLTMDDRAVDFLEVAPDNWIGVGGTY
                     GEGLARLAERFPLSCHGLSLSLGGPEPLDHVFLHRVRKFLDQHHVPLFSEHLSYCSDDG
                     HLYDLIPMPFTDEAVQHIAGRIREVQDILGRRIAVENISYYAAPYQALSEIDFLRAVLS
                     EADCDLLLDVNNLYVNAHNHGYDAASFLARVPADRVVCLHVAGHYDEAPDLKVDTHGAA
                     VKDDVWTLLASAYQHLGTVPTLLERDFNLPPLAELLGEVDYIRRLQSTVRQPEVRHG"
     PFAM_domain     3784..4569
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2404_0005"
                     /evalue="4.20E-102"
                     /label="ctg1_2404"
                     /locus_tag="ctg1_2404"
                     /protein_end="268"
                     /protein_start="6"
                     /score="341.0"
                     /tool="antismash"
                     /translation="GAGLGLRRALLPDLLTMDDRAVDFLEVAPDNWIGVGGTYGEGLAR
                     LAERFPLSCHGLSLSLGGPEPLDHVFLHRVRKFLDQHHVPLFSEHLSYCSDDGHLYDLI
                     PMPFTDEAVQHIAGRIREVQDILGRRIAVENISYYAAPYQALSEIDFLRAVLSEADCDL
                     LLDVNNLYVNAHNHGYDAASFLARVPADRVVCLHVAGHYDEAPDLKVDTHGAAVKDDVW
                     TLLASAYQHLGTVPTLLERDFNLPPLAELLGEVDYIRRLQ"
     CDS             4598..5386
                     /locus_tag="ctg1_2405"
                     /transl_table=11
                     /translation="MAESLREQQLRMTRFIRDPQANEPPPGIEARRLAVYRQLFFGNLQ
                     SLLAGNFPVLQASLAHEHWQALTEDFYAGFRCQTPLFTEVAGEFVDYLESRGEQPGWVA
                     ELAHYEWIETALLLSDKAEPAHDPDGDLLDGVPQLSSLALPLAYVWPVSHIGPEHIPLQ
                     APTEPTLLLARRGADLKVHFSRLAPLAHALLVSLQQWQLTGREHLKALAEIAGIELAAI
                     EEQGIALLRSLKEQGVVIGTRPNCTTPRRPPLARPEGEAS"
     PFAM_domain     4616..4876
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2405_0006"
                     /evalue="3.30E-21"
                     /label="ctg1_2405"
                     /locus_tag="ctg1_2405"
                     /protein_end="93"
                     /protein_start="6"
                     /score="75.4"
                     /tool="antismash"
                     /translation="EQQLRMTRFIRDPQANEPPPGIEARRLAVYRQLFFGNLQSLLAGN
                     FPVLQASLAHEHWQALTEDFYAGFRCQTPLFTEVAGEFVDYL"
     CDS             5383..5805
                     /locus_tag="ctg1_2406"
                     /transl_table=11
                     /translation="MTDTLASVIYTANTHTTGGRDGRGQTVDADLDLPLSPPGSGRPGT
                     NPEQLFAIGWSACFIGALRRAGQKLNVRLPADVAVDAEVSLGNTADGGFALAAQLTVHL
                     PGLQAEDKEKLVDEAHQICPYSKATRGNIEVGFVIP"
     aSDomain        5407..5790
                     /aSDomain="TIGR03561"
                     /aSTool="tigrfam"
                     /description="organ_hyd_perox: peroxiredoxin, Ohr
                     subfamily"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2406_0001"
                     /evalue="4.30E-47"
                     /identifier="TIGR03561"
                     /label="ctg1_2406"
                     /locus_tag="ctg1_2406"
                     /protein_end="136"
                     /protein_start="8"
                     /score="157.8"
                     /tool="antismash"
                     /translation="IYTANTHTTGGRDGRGQTVDADLDLPLSPPGSGRPGTNPEQLFAI
                     GWSACFIGALRRAGQKLNVRLPADVAVDAEVSLGNTADGGFALAAQLTVHLPGLQAEDK
                     EKLVDEAHQICPYSKATRGNIEVG"
     PFAM_domain     5503..5787
                     /aSDomain="OsmC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02566.21"
                     /description="OsmC-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2406_0007"
                     /evalue="4.10E-14"
                     /label="ctg1_2406"
                     /locus_tag="ctg1_2406"
                     /protein_end="135"
                     /protein_start="40"
                     /score="52.9"
                     /tool="antismash"
                     /translation="GRPGTNPEQLFAIGWSACFIGALRRAGQKLNVRLPADVAVDAEVS
                     LGNTADGGFALAAQLTVHLPGLQAEDKEKLVDEAHQICPYSKATRGNIEV"
     CDS             complement(5944..7404)
                     /NRPS_PKS="Domain: Aminotran_1_2 (138-460). E-value: 2e-29.
                     Score: 94.6. Matches aSDomain:
                     nrpspksdomains_ctg1_2407_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 211.9; E-value:
                     2.5e-64)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2407"
                     /transl_table=11
                     /translation="MNPFNPKLLACEMTVKPCIDTVSILRHALESGRGTKYKRLASALE
                     LCILDGSLAAGSKLTPQRILAYKLNVTVGTVSRAYAELERMGLVVPRVGDGTFVRQRGL
                     ERKRDEGYRNVAESPAFYDMSRNLHIPGAETSLLAQSLMVLAQDVSTLGELMTYTPEVG
                     LPRFRAAGAKWLSSHGFRAHPEQVLCTNGSQHALLCTLMALLRPGDTLVTEPLTYPGLI
                     SAARLLGIRLLAATMDDDGLLPQSLDELCRLHRVTALYCTPTLQNPTTSILPTERRQAI
                     ATICREHNLLIIEDETHAVLLEDRPAPLSHFVPERSILIGGMSKVVAAGLRVGYLHAPV
                     AVVSRLAAALRGSCWMATPLPLELATRWIDDGTAQILLQQQAAEIARRKALVTQLLEGL
                     NYRTHSRSPHFWIQVPEPWRASDVESDLAAKHYRIATAESFAVGHAAVPQFVRVSICDG
                     AMDDVQLCLGFQALSVALDSDTASTERS"
     aSDomain        complement(6025..6990)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2407_Aminotran_1_2.1"
                     /evalue="2.00E-29"
                     /label="ctg1_2407_Aminotran_1_2.1"
                     /locus_tag="ctg1_2407"
                     /protein_end="460"
                     /protein_start="138"
                     /score="94.6"
                     /tool="antismash"
                     /translation="AQSLMVLAQDVSTLGELMTYTPEVGLPRFRAAGAKWLSSHGFRAH
                     PEQVLCTNGSQHALLCTLMALLRPGDTLVTEPLTYPGLISAARLLGIRLLAATMDDDGL
                     LPQSLDELCRLHRVTALYCTPTLQNPTTSILPTERRQAIATICREHNLLIIEDETHAVL
                     LEDRPAPLSHFVPERSILIGGMSKVVAAGLRVGYLHAPVAVVSRLAAALRGSCWMATPL
                     PLELATRWIDDGTAQILLQQQAAEIARRKALVTQLLEGLNYRTHSRSPHFWIQVPEPWR
                     ASDVESDLAAKHYRIATAESFAVGHAAVPQFVRVSICDGAM"
     PFAM_domain     complement(6025..6990)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00155.23"
                     /description="Aminotransferase class I and II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2407_0009"
                     /evalue="7.60E-27"
                     /label="ctg1_2407"
                     /locus_tag="ctg1_2407"
                     /protein_end="460"
                     /protein_start="138"
                     /score="94.5"
                     /tool="antismash"
                     /translation="AQSLMVLAQDVSTLGELMTYTPEVGLPRFRAAGAKWLSSHGFRAH
                     PEQVLCTNGSQHALLCTLMALLRPGDTLVTEPLTYPGLISAARLLGIRLLAATMDDDGL
                     LPQSLDELCRLHRVTALYCTPTLQNPTTSILPTERRQAIATICREHNLLIIEDETHAVL
                     LEDRPAPLSHFVPERSILIGGMSKVVAAGLRVGYLHAPVAVVSRLAAALRGSCWMATPL
                     PLELATRWIDDGTAQILLQQQAAEIARRKALVTQLLEGLNYRTHSRSPHFWIQVPEPWR
                     ASDVESDLAAKHYRIATAESFAVGHAAVPQFVRVSICDGAM"
     PFAM_domain     complement(7108..7296)
                     /aSDomain="GntR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00392.23"
                     /description="Bacterial regulatory proteins, gntR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2407_0008"
                     /evalue="5.50E-10"
                     /label="ctg1_2407"
                     /locus_tag="ctg1_2407"
                     /protein_end="99"
                     /protein_start="36"
                     /score="38.8"
                     /tool="antismash"
                     /translation="YKRLASALELCILDGSLAAGSKLTPQRILAYKLNVTVGTVSRAYA
                     ELERMGLVVPRVGDGTFV"
     CDS             7450..8391
                     /gene_functions="transport (smcogs) SMCOG1166:transporter,
                     EamA family (Score: 187.2; E-value: 7.3e-57)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2408"
                     /transl_table=11
                     /translation="MTISASQELTPIARKSWLAGAVTAALFLTVCLSWGTTWLGIRIAV
                     ETVPPLTASGLRFLIAFPLFLAFARMRGDAIVFPRQSRGFFIFVTLCYFGVPYFLLNYG
                     ETLVSSGLTALLFSCMPVFILIFSAIFLRERIQTLQVIGIAIGFASLYMILREQGLGFE
                     HQGFIGVLAILAAALMHALCYVVTKQRGSAISVVTYNTLPIGIAGLALFVLGLLVEQPS
                     FSQISSRSWWALTYLGLCASVGGFLVYFFLLKRLSPVVLSFVFIIFPVFAVIIGAWYEG
                     QAISTRLALYSLLLLLGFAITKLPLASLFARK"
     PFAM_domain     7522..7914
                     /aSDomain="EamA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00892.22"
                     /description="EamA-like transporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2408_0010"
                     /evalue="1.40E-25"
                     /label="ctg1_2408"
                     /locus_tag="ctg1_2408"
                     /protein_end="155"
                     /protein_start="24"
                     /score="90.2"
                     /tool="antismash"
                     /translation="ALFLTVCLSWGTTWLGIRIAVETVPPLTASGLRFLIAFPLFLAFA
                     RMRGDAIVFPRQSRGFFIFVTLCYFGVPYFLLNYGETLVSSGLTALLFSCMPVFILIFS
                     AIFLRERIQTLQVIGIAIGFASLYMIL"
     PFAM_domain     7951..8352
                     /aSDomain="EamA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00892.22"
                     /description="EamA-like transporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2408_0011"
                     /evalue="1.00E-15"
                     /label="ctg1_2408"
                     /locus_tag="ctg1_2408"
                     /protein_end="301"
                     /protein_start="167"
                     /score="58.2"
                     /tool="antismash"
                     /translation="IGVLAILAAALMHALCYVVTKQRGSAISVVTYNTLPIGIAGLALF
                     VLGLLVEQPSFSQISSRSWWALTYLGLCASVGGFLVYFFLLKRLSPVVLSFVFIIFPVF
                     AVIIGAWYEGQAISTRLALYSLLLLLGFAI"
     CDS             complement(8459..8968)
                     /locus_tag="ctg1_2409"
                     /transl_table=11
                     /translation="MTLLTLNPIKTVLDQLDRLAAWGWDIPLRLFLAWEFFESGLEKWH
                     GDNWFEQIHASFPFPFNHFSAGFDWQVSMWAELIAPILLLLGVATRFASASLIVVTIVA
                     IAAVHWPAQWSTLSELAQGYSITDHGFGNYKLPLIYLVALLPLLLKGAGALSVDGMIRR
                     LYRSHS"
     PFAM_domain     complement(8639..8890)
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2409_0012"
                     /evalue="4.90E-19"
                     /label="ctg1_2409"
                     /locus_tag="ctg1_2409"
                     /protein_end="110"
                     /protein_start="26"
                     /score="68.8"
                     /tool="antismash"
                     /translation="PLRLFLAWEFFESGLEKWHGDNWFEQIHASFPFPFNHFSAGFDWQ
                     VSMWAELIAPILLLLGVATRFASASLIVVTIVAIAAVHW"
ORIGIN
        1 tcagttgatc aactggtcga tcagcacggc gttggtgtag atcaggctgc catcactggc
       61 ccggtggccc accaggtgga attgcccacg gtgttccact ccgcccaggt acacgcggaa
      121 catgcagtcc gccagcggcc cgtagccttc gggcatgtgc agatcgaggg tgtcgaggtc
      181 ggcatcgacc atcatttccc gctggccgtt ctcctgcagg tagacctcgg cctgttcgag
      241 gtgcaggcgg tcctggtcgg tcaggtagaa gcggatgtct tccagcggcg tgggtttctg
      301 ctcggcggtg gtcttgcacc agccttcgag ggtcattgcg ctcatggtga ggtgcctccg
      361 gggttcgcgt gaggattacc gcgctgtcgg agagttggac cgccgcgccg ttggattcga
      421 tcattttttg ttcaggcggt ttgccgagcg atagtaacgg gcataaaaaa agccgctcca
      481 gaggagcggc tcgaaggacg tcgaaggagc aatcacaata tcaacgtcag gagttgtctt
      541 ccgcagggaa agtgcggaag cgggaagatg gggtcattct agaaagttgc agccgcagga
      601 taaaccgtca ttccgggaag agactttctg tccgggcgta ataatctcac ccgaacgcgg
      661 ggcgaacatt cagacgaatc cgaaagttgc cccgcgcaat tatcgtggca aatatccggg
      721 tcgattacag gatcgacagc ggatattcga cgatcaggcg catctcgttg ttgtccgcct
      781 cgccctggtc ggcattggcg cggtggaacg cctggcgcag gcggaaggac aggtccttcg
      841 ccgggccgcc ctggaccacg tacttggctt ccaggtcggt ctcgtggtgg ctgccgtcct
      901 caccgtacag accggcgtag gcgccatccg cgtcggcgtg gctgccgtcg atgccggtac
      961 cgttgatgta gcgggccatg aagctcaggc ccggcacgcc gtaggtgtcc atcgccaggt
     1021 cgtagcgaac ctgccaggag cgctcgcccg gaccgttgaa gtcggagtac tgcacggagt
     1081 tggcgaggaa taccgagtca ccggtggcgc cggcgccgtc gtcgccgaag cccacgtagt
     1141 cgaacggcgt atcgccgtgc accttctggt aggccagggt gacagtgtgt gcctgcagga
     1201 aggagtaggc ggctgccagc gaccaggtgg tgttgctgat ctcgccggcc tctgcccggc
     1261 cttcgtcgtt ggtgcggtag atgttgaagt cgaaggccag cgactggtca tcggcgaccg
     1321 gcagcaccca gttcaggttg ccgtagtact ggcgccagat gtccttgaac tcggagccgt
     1381 acagcgaaac gctcaggttg tcgttgatcg cgtacttgcc gccgaggaag tcgacgtcgc
     1441 tggtttcacg taccgcgtag gccgcccaca ggcctccgtc gcgggcagtg gtgaccgggc
     1501 tggtgccaga ggtgaagtgc ccggcttcca ggtccaggcc ttcgatctcg ctgctcagca
     1561 ggttgaagcc cgaagcggtc tgcgggatca ggcgggtgcc gccggcggcg aacaccggag
     1621 cggtcggctg catgtcaccg aatttcagct cggtcttgga gatgcgcacc ttcagcgcgc
     1681 caccggcctt gccgtagtcg tcgtccggct tgccgtcgtt gcctaccggc aggttaccgg
     1741 tgcccgcgcg accgcggccg gcgtcgagct tgatgcccag gtagccgaag gcatccacgc
     1801 cgaagccgac ggtaccctgg gtgtagccgg atgagaagtt ggccaggaag ccctgggtcc
     1861 agtcgcggtt gtcggcgaag ccgttcttgc cgtcgtggtc gtagtactgg ttgcgcagca
     1921 ggacgtcgag cttggcgtcc tcgacgaggc ccttggcatc ggcctgatcg gtgacgaagg
     1981 gctcggcagc ggcgaactgg ctggcggcgg cggaaacagc gagcacgatg gcgctgcgtt
     2041 taaggtgctt catggatatt gcccctagag tcttggagga ccggctcgat taatagcgtg
     2101 agagccggac gtttttatag gcaggcacaa tgagtccgaa catggattaa ccacggcgga
     2161 aaatcgcagg aagttgcgtt ggcattgttg cagttaactg gcttttaatt cccccgcgaa
     2221 ttgctccaga cgcggaagag ccgacgtcat aatgcccaaa gagttcgccg tttaaatcac
     2281 ggattatgag aaggtctata tcctgaattg taataatcag gacttttgtc gagttgacac
     2341 aacagcttcg caagttttat cgggactggg catttcactg tttccggggg ctgcgggcac
     2401 ggtgacatgg cgcgtggcgg ggcgatacgg ctaagctgcg cgacccggcc gccacacctg
     2461 gtgcggcgac gtgccccatt catcgacagc agagatttgt cccatgacgc ctaccttcat
     2521 ccccgacgcg gaccccgaat ccatttcctc cgacgtcgcc ggcttcggcg gcctgctggt
     2581 ttccacgcag atccccaccc ttgaggacgg cagcctggag ctgggcgaca tcaaggccca
     2641 gagcgaagct accctgcgca gcctgcaact cgccctggaa aaggccggca gcggcctgga
     2701 ccacgtactg cacctgacca tctacctcac cagcatggcc gatcgcgccg cattcaacga
     2761 ggtgtactgc agcttcttcg ccaaacccta cccggtgcgc gccgccgtgg gtatcgccga
     2821 actggcagtg gagggcatga aggtcgaggt taccgccatc gctgcaaagc gcgcgggctg
     2881 atcgtcctgc ctctccaggc atgggccgcc ttgcggccct ttccctttcc cgccgctgtg
     2941 acatcggcag cgttccccgc tccagatccc cgctgcttgt attgctttgt atctgccgct
     3001 ctctgagcgg acacacgcat acaaaagcct ccagtcgccg atacgcccgc gatacatcgt
     3061 tgcggcgaaa tagccctacc cgaacgacac accgcgacgg cagggaaaac cctccagagc
     3121 atcgttccag ggattcgccc ttgcggcatg acccggcgcc cagcgcgcca ttgcatctgg
     3181 agaagcacca tgactcgact ctcgaaatcc cagcttggcc tgatcgccgt tgccctggcc
     3241 ggcggcctga acatggcgtc ctccgccttc gccgtcgaag ccctgccgca gggctaccag
     3301 ctggcctccg ccgccaaggc cggggagggc aagtgtggcg agggcaagtg cggcgccgcc
     3361 aagcaaacca aggccagcca gactgaaggc aagtgcggcg aaggcaaatg cggtgccgac
     3421 ggcgcccagg ccaaggctac tggcgccgag ggcaagtgcg gtgagggcaa gtgtggtgac
     3481 gcctcgttcg cccgtaccga tgccgaccac gacggccgcg tctcccgcgc cgaattgctg
     3541 gccgtggcgc ccaaggccaa cgccgagttc gatgccatcg atgccaacca cgacggctac
     3601 ctctccgaag ccgaggtcta ccagttccgc aagaaccagt tcgactccaa cggcaagccg
     3661 ttcccggccg acctttacag caagctgagc caggccagga actgacattc ccgcagacct
     3721 ccccgcgccc caggccgggg agggcacttc gcccaggaga ccgccatgac cacttctctc
     3781 aatggagccg gcctaggcct gcgccgcgcc ctgctgcccg acctgctgac aatggacgac
     3841 cgcgccgtgg atttcctcga agtcgccccg gacaactgga tcggtgtcgg cggcacctat
     3901 ggcgaaggcc tggcgcgcct ggccgaacgc ttcccgctgt cctgccacgg cctgtcgctg
     3961 tccctcggcg gccccgagcc tctggaccac gtgttcctgc accgtgtccg caagttcctc
     4021 gaccagcacc atgttccgct gttcagcgaa cacctgagct actgctccga cgacggccac
     4081 ctctacgacc tgattccgat gcccttcacc gacgaagcgg tgcagcacat cgccgggcgc
     4141 atccgtgaag tgcaggacat ccttggccgc cgcatcgccg tggaaaacat ctcctactac
     4201 gccgcgccct accaggctct gagcgaaatc gatttcctgc gcgccgtgct gagcgaggcc
     4261 gactgcgacc tgctgctgga cgtcaacaac ctctacgtca atgcccacaa ccacggctac
     4321 gacgccgcca gcttcctggc ccgcgtgccg gcggatcgtg tcgtctgcct acacgtcgcc
     4381 gggcattacg acgaggcgcc ggaccttaag gtcgacaccc acggcgcagc ggtgaaggac
     4441 gatgtctgga ccttgctggc cagcgcctac cagcatctgg gcaccgtccc gaccctgctg
     4501 gaacgcgact tcaacctgcc gccgctcgcc gaattgctcg gcgaggtgga ctacatccgc
     4561 cgcctgcaaa gcaccgttcg ccagccggag gtgcgccatg gctgagtccc tgcgcgaaca
     4621 gcagttgcgc atgacccgct tcatccgcga cccgcaggcc aatgaaccgc cgcccggtat
     4681 cgaggcgcgg cgcctggcgg tgtaccggca actgttcttc ggcaacctgc aatcgctgct
     4741 ggccggcaac ttcccggtgc tgcaggccag cctcgcgcac gagcattggc aagcgctgac
     4801 cgaggatttc tacgccggct tccgttgcca gacgccgctc ttcacggagg ttgccggcga
     4861 gttcgtcgac tacctcgaaa gccgcggcga gcagcccggc tgggtggccg agctggccca
     4921 ctacgaatgg atcgagaccg cgctgctgct cagcgacaag gccgaaccgg cccacgatcc
     4981 ggacggcgac ctgctcgatg gcgtaccgca gctttccagc ctcgcgctgc cgctggccta
     5041 cgtctggccg gtcagccaca tcggcccgga gcatatcccg ctgcaagccc cgaccgagcc
     5101 gacactgctg ctggcacgcc gcggcgcgga cctgaaggtg cacttctcgc gcctggcccc
     5161 gctggcccat gcgctgctgg tgtcgctgca gcaatggcaa ctgaccggtc gcgaacacct
     5221 gaaggcgctg gcggaaatcg ccggcatcga actggccgcc atcgaagagc agggcatcgc
     5281 cctgctgcgc agcctgaaag agcaaggcgt ggtgatcggc acccgcccca actgcaccac
     5341 accgcgtcgt ccccccttgg cccgccctga aggagaagcg tcatgaccga taccctggca
     5401 agcgtgatct acaccgccaa cacccacact accggaggtc gcgacggtcg cggccagact
     5461 gtcgacgctg acctggatct gcccctgagc ccgcctggtt ccggccgccc cggcaccaac
     5521 cccgagcagc tgttcgccat tggctggtcc gcctgcttca tcggtgccct gcgccgcgcc
     5581 gggcagaaac tgaacgtgcg cctgccagcc gatgtggcgg tggacgccga agtctccctg
     5641 ggcaacaccg ccgacggcgg tttcgccctg gctgcccagc tcaccgtgca cctgccgggg
     5701 ctgcaggccg aggacaagga gaagctggtc gatgaggctc accagatctg tccgtactcc
     5761 aaggcgactc gcggcaatat cgaggttggg ttcgtgattc cctgatctgc ttgttatcca
     5821 cagcccagcc cgcgtaccgt catcggtgcg cgggcttttt tcttttccgt aggagcgagc
     5881 ttgctcgcga accggcctgg ctgcagacca gccggggaaa tccgttcgcg agcaccctct
     5941 cgcctatgag cgttccgtgg acgcggtatc actgtccaga gcgaccgaga gcgcctggaa
     6001 tcccaaacac aactgcacgt catccatcgc tccgtcgcag atgctgaccc tgacgaactg
     6061 cggaactgca gcgtgaccga cagcaaagga ttccgcggtc gcgatgcggt agtgcttggc
     6121 cgccaagtcg ctttccacgt ccgaggcgcg ccatggctcg ggcacctgga tccagaaatg
     6181 cgggctcctg gagtgagttc ggtagttcaa tccttccagc aactgcgtca ccagtgcctt
     6241 gcggcgagcg atctcggcgg cttgctgctg cagcagaatc tgcgcggtgc cgtcatcgat
     6301 ccagcgggtg gccaactcca gggggagggg agttgccatc cagcaggagc ctcgcagcgc
     6361 tgctgccagc cggctcacca ccgctacggg ggcgtgcagg tagccaacgc gaaggccggc
     6421 ggcgaccacc ttgctcatgc cgccaatcag aatgcttcgc tcggggacga agtgactcaa
     6481 gggcgcgggc cgatcttcca gcaggaccgc atgggtctcg tcctcgatga tcagcaggtt
     6541 gtgctcccgg caaatcgtcg cgatggcctg ccgacgttcc gtgggcagga tggaggtcgt
     6601 gggattctgc agagtggggg tgcaatacag ggcagtaact cggtgcagtc ggcagagttc
     6661 gtccagcgac tgagggagca atccgtcgtc gtccatcgtc gccgccagaa gacgaatacc
     6721 cagcagccgc gccgcactga tcaggccagg gtaggtgaga ggttcggtca ccagggtgtc
     6781 gccgggccgc agcagcgcca tcagcgtaca aagcaaggcg tgctggctgc cgttggtgca
     6841 cagcacctgc tcagggtgag cgcggaaacc atggctggaa agccacttcg ccccggcagc
     6901 acggaagcgc ggcaggccga cctccggcgt gtaggtcatc agctctccca gcgtgctcac
     6961 atcctgtgca aggaccatca ggctctgtgc cagcaggctg gtctcggccc cagggatgtg
     7021 caggttgcgg ctcatgtcgt agaacgccgg ggactcagcg acattgcggt aaccctcatc
     7081 tcgcttgcgc tccagaccac gctggcgaac gaaagtccca tcgcccaccc ttggcactac
     7141 caggcccatg cgctcgagtt cggcgtaggc gcggctcacg gtgcccacgg tgacattgag
     7201 tttgtaggcc agaatgcgtt ggggagtgag cttgctgccg gctgcgaggg agccatcgag
     7261 aatgcataac tccaaggctg acgcgaggcg tttgtatttt gtgccgcgcc ccgattccag
     7321 tgcgtggcgg agaattgaca cggtgtcaat acagggtttg acagtcattt cacaggccaa
     7381 tagcttcgga ttgaacgggt tcattgtagt aacaagaatc catccatagc gctatctgga
     7441 gctgctgtca tgaccatttc cgcttcccag gaactcactc ctattgcccg gaagagttgg
     7501 ctggcaggtg ccgtgacggc cgcgctgttc ctgactgtct gcctcagttg gggcacgacc
     7561 tggctgggta tccgcatcgc cgttgaaacg gtgccaccgc tgacggcatc cggtctgcgc
     7621 ttcctgattg cctttccatt gttcctggca ttcgcccgga tgcgcggtga tgcgattgtc
     7681 ttccctcgac aaagccgggg cttcttcatt ttcgtcacgc tttgctactt cggtgtgccg
     7741 tacttcctcc tcaactacgg cgagaccctg gtttcctcag ggctgacagc gctgctgttc
     7801 agttgcatgc ccgtcttcat cctgatcttc tcggcgatat tcctgcgaga aaggattcag
     7861 acactccagg tgatcggcat cgccatcggc tttgccagcc tgtacatgat tcttcgtgag
     7921 cagggcctgg gtttcgaaca ccagggtttc attggtgtgc tggccatcct tgccgccgcg
     7981 ctgatgcatg ccctgtgtta tgtggtgacc aagcagagag gctcggcgat cagcgtcgtt
     8041 acctacaaca ctctgcccat cggcattgcc gggttggcgc tgttcgtcct cggattgctg
     8101 gtggagcagc cgtcgttttc gcagatatcc tccaggtcct ggtgggcgct gacatacctc
     8161 gggctgtgcg cctcggtcgg tggtttcctc gtctacttct tcttgttgaa acgactgagc
     8221 cccgtggtcc tgtcctttgt gttcatcatt ttccctgttt ttgcggtgat catcggggct
     8281 tggtacgagg ggcaagcgat ttccacccgc ctggcgctct attcgctgct gttattgctg
     8341 ggttttgcca tcaccaaatt acctctggcg tcgctgtttg cgcgcaagta atgggggcgt
     8401 ctgctgcgga agcgacaagg gaaaggcaaa cctgcctttc ccttgtccga agccagggtc
     8461 agctgtgcga gcgatacagc cggcggatca ttccatccac actcagcgct cccgcacctt
     8521 tcaacagcag cggcagcagt gcgaccaggt agatcagcgg cagcttgtag ttgccgaagc
     8581 cgtggtcggt gatcgagtag ccctgggcga gctcggacaa ggtcgaccac tgcgccggcc
     8641 agtgcaccgc ggcgatggcg acgatggtga cgacgatcag cgacgcggac gcgaagcgcg
     8701 tggccacgcc gagcaggagc aggatcggcg cgatcagttc ggcccacatc gatacctgcc
     8761 agtcgaagcc ggcggagaag tggttgaagg ggaaggggaa gctggcgtgg atctgttcga
     8821 accagttgtc gccatgccat ttctccaggc ctgattcgaa gaactcccag gccaggaaca
     8881 gccgcagggg aatgtcccag ccccaggcgg cgaggcggtc gagttggtcg aggacggtct
     8941 tgatcgggtt cagggtcagc agggtcat
//
