LOCUS       NZ_CP102292.1          18056 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP102292.1 [Ruminococcus] lactaris ATCC 29176 chromosome,
            complete genome.
ACCESSION   NZ_CP102292
VERSION     NZ_CP102292.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:46:26
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2374597
            Orig. end    :: 2392653
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1488)
                     /locus_tag="ctg1_2106"
                     /transl_table=11
                     /translation="MEKETFDGNDIEVTETETSEQQVSEETEKPHKWRKPLLITLGGIA
                     GTTAAVYIGTAAYFYFHCLPNTEINGKDFSYANRAEIEDYLKEDTKNYVLEIKGRENVK
                     DQIQGSEIGVEYEADDAAGKLLREQNFWLWPVAFDREQTLEIPVSVSYDKEKLKEKIST
                     LNVVTGEQTQPASSTPFFDGEKFVPGEEGKGTAVDVDTLNEVIGDAVSHLTEELELDDT
                     GCYVRPKYIKDSPEVQAACDQMNPYLKARITYEMDEPVVVDGTVISQWVTADENFAVTF
                     HPELVQEWLKQFAEKYDTVGKTRTFTTADGRSAQVSGGTYGWEIDEESELTALLANIEN
                     GDTVSREPAYVEGKTAISHGASDWGTTYAEVDLTNQKMWYVRDGQILMSTDIVTGLPTR
                     ARQTPEGVYTILERMRNKTLRGALKPDGTYEYETPVDYWMRVTYSGVGFHDATWQRTFG
                     GDVYTYRGSHGCINMSYSDAGQLYDLIQVGDPVVIHY"
     protocluster    1..18056
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2383604:2383871](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(9008..9274)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..18056
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18056
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="4"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     PFAM_domain     complement(10..390)
                     /aSDomain="YkuD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03734.16"
                     /description="L,D-transpeptidase catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2106_0068"
                     /evalue="1.40E-21"
                     /label="ctg1_2106"
                     /locus_tag="ctg1_2106"
                     /protein_end="493"
                     /protein_start="366"
                     /score="77.6"
                     /tool="antismash"
                     /translation="TYAEVDLTNQKMWYVRDGQILMSTDIVTGLPTRARQTPEGVYTIL
                     ERMRNKTLRGALKPDGTYEYETPVDYWMRVTYSGVGFHDATWQRTFGGDVYTYRGSHGC
                     INMSYSDAGQLYDLIQVGDPVVI"
     PFAM_domain     complement(466..783)
                     /aSDomain="PG_binding_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12229.10"
                     /description="Putative peptidoglycan binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2106_0067"
                     /evalue="1.20E-12"
                     /label="ctg1_2106"
                     /locus_tag="ctg1_2106"
                     /protein_end="341"
                     /protein_start="235"
                     /score="48.2"
                     /tool="antismash"
                     /translation="EVQAACDQMNPYLKARITYEMDEPVVVDGTVISQWVTADENFAVT
                     FHPELVQEWLKQFAEKYDTVGKTRTFTTADGRSAQVSGGTYGWEIDEESELTALLANIE
                     NG"
     PFAM_domain     complement(853..1140)
                     /aSDomain="PG_binding_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12229.10"
                     /description="Putative peptidoglycan binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2106_0066"
                     /evalue="8.30E-05"
                     /label="ctg1_2106"
                     /locus_tag="ctg1_2106"
                     /protein_end="212"
                     /protein_start="116"
                     /score="22.9"
                     /tool="antismash"
                     /translation="EADDAAGKLLREQNFWLWPVAFDREQTLEIPVSVSYDKEKLKEKI
                     STLNVVTGEQTQPASSTPFFDGEKFVPGEEGKGTAVDVDTLNEVIGDAVSH"
     CDS             complement(1730..2611)
                     /locus_tag="ctg1_2107"
                     /transl_table=11
                     /translation="MEKRINGHTRLYALIGSPVGHSGSPAMQNYSFEKLGIDAAYLAFD
                     VNVGQTAKALEAFRTLNVGGFNVTMPCKTEVARLVDRLSPAAELIGACNTVVVEEDGTM
                     TGHITDGTGFVRNLKEHSVEVKDQKIVVLGTGGAATAIAVQAALDGVAEIAIFNRKDEF
                     FANGEKTVEKIKKAVPTIGKVYIEDLDNTEKLRAVIAESDILINATRAGMAPLQDVIPV
                     PEDVLRPELAVADVVYNPLETLLVKKAKEAGCRAAIGGIGMLLWQGAAAFELFTGKEMP
                     VEEVKEKFFSEA"
     aSDomain        complement(1745..2581)
                     /aSDomain="TIGR00507"
                     /aSTool="tigrfam"
                     /description="aroE: shikimate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2107_0025"
                     /evalue="2.30E-66"
                     /identifier="TIGR00507"
                     /label="ctg1_2107"
                     /locus_tag="ctg1_2107"
                     /protein_end="289"
                     /protein_start="10"
                     /score="221.7"
                     /tool="antismash"
                     /translation="LYALIGSPVGHSGSPAMQNYSFEKLGIDAAYLAFDVNVGQTAKAL
                     EAFRTLNVGGFNVTMPCKTEVARLVDRLSPAAELIGACNTVVVEEDGTMTGHITDGTGF
                     VRNLKEHSVEVKDQKIVVLGTGGAATAIAVQAALDGVAEIAIFNRKDEFFANGEKTVEK
                     IKKAVPTIGKVYIEDLDNTEKLRAVIAESDILINATRAGMAPLQDVIPVPEDVLRPELA
                     VADVVYNPLETLLVKKAKEAGCRAAIGGIGMLLWQGAAAFELFTGKEMPVEEVKEKF"
     PFAM_domain     complement(1751..1834)
                     /aSDomain="SDH_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18317.3"
                     /description="Shikimate 5'-dehydrogenase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2107_0070"
                     /evalue="1.20E-11"
                     /label="ctg1_2107"
                     /locus_tag="ctg1_2107"
                     /protein_end="287"
                     /protein_start="259"
                     /score="44.3"
                     /tool="antismash"
                     /translation="GIGMLLWQGAAAFELFTGKEMPVEEVKE"
     PFAM_domain     complement(2324..2572)
                     /aSDomain="Shikimate_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08501.13"
                     /description="Shikimate dehydrogenase substrate binding
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2107_0069"
                     /evalue="3.30E-27"
                     /label="ctg1_2107"
                     /locus_tag="ctg1_2107"
                     /protein_end="96"
                     /protein_start="13"
                     /score="94.7"
                     /tool="antismash"
                     /translation="LIGSPVGHSGSPAMQNYSFEKLGIDAAYLAFDVNVGQTAKALEAF
                     RTLNVGGFNVTMPCKTEVARLVDRLSPAAELIGACNTV"
     CDS             complement(2770..3255)
                     /locus_tag="ctg1_2108"
                     /transl_table=11
                     /translation="MNQKLYNPKFKEKKTAAEKKKKTRNIVIIAVILVLASVATYWMMP
                     RTGSLEDSTLFDEATVKSQAEKVIGYINADDYESLQDVSADKMKEIMTEERLSEAKEKV
                     SDDWGAFKSMGDISTTTISKRGVNAAVAYVTATYENVEIHYTLAFDEDMKLASFGMQ"
     PFAM_domain     complement(2782..3063)
                     /aSDomain="DUF3887"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13026.8"
                     /description="Protein of unknown function (DUF3887)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2108_0071"
                     /evalue="3.20E-21"
                     /label="ctg1_2108"
                     /locus_tag="ctg1_2108"
                     /protein_end="158"
                     /protein_start="64"
                     /score="76.0"
                     /tool="antismash"
                     /translation="AEKVIGYINADDYESLQDVSADKMKEIMTEERLSEAKEKVSDDWG
                     AFKSMGDISTTTISKRGVNAAVAYVTATYENVEIHYTLAFDEDMKLASF"
     CDS             complement(3361..3963)
                     /locus_tag="ctg1_2109"
                     /transl_table=11
                     /translation="MYITCLDVEGVLVPEIWVAFAEASGIPELKRTTRDEPDYDKLMNW
                     RLGILREHGLGLKEIQETIAKIDPLPGAKEFLDELRTFSQVILISDTFTQFATPLMEKL
                     GWPTLFCNSLEVAENGEITGFKMRTEQSKLSTVKALQSIGFETIASGDSYNDLGMIQAS
                     SAGFLFRSTEKIKADYPEIPAYESYDELLTAIKKAMK"
     aSDomain        complement(3370..3963)
                     /aSDomain="TIGR02137"
                     /aSTool="tigrfam"
                     /description="HSK-PSP: phosphoserine phosphatase/homoserine
                     phosphotransferase bifunctional protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2109_0026"
                     /evalue="1.20E-70"
                     /identifier="TIGR02137"
                     /label="ctg1_2109"
                     /locus_tag="ctg1_2109"
                     /protein_end="198"
                     /protein_start="0"
                     /score="235.1"
                     /tool="antismash"
                     /translation="MYITCLDVEGVLVPEIWVAFAEASGIPELKRTTRDEPDYDKLMNW
                     RLGILREHGLGLKEIQETIAKIDPLPGAKEFLDELRTFSQVILISDTFTQFATPLMEKL
                     GWPTLFCNSLEVAENGEITGFKMRTEQSKLSTVKALQSIGFETIASGDSYNDLGMIQAS
                     SAGFLFRSTEKIKADYPEIPAYESYDELLTAIKKA"
     PFAM_domain     complement(3478..3789)
                     /aSDomain="Hydrolase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00702.28"
                     /description="haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2109_0072"
                     /evalue="4.10E-07"
                     /label="ctg1_2109"
                     /locus_tag="ctg1_2109"
                     /protein_end="162"
                     /protein_start="58"
                     /score="30.6"
                     /tool="antismash"
                     /translation="EIQETIAKIDPLPGAKEFLDELRTFSQVILISDTFTQFATPLMEK
                     LGWPTLFCNSLEVAENGEITGFKMRTEQSKLSTVKALQSIGFETIASGDSYNDLGMIQA
                     "
     aSDomain        complement(3478..3795)
                     /aSDomain="TIGR01488"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IB: HAD phosphoserine phosphatase-like
                     hydrolase, family IB"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2109_0027"
                     /evalue="1.70E-12"
                     /identifier="TIGR01488"
                     /label="ctg1_2109"
                     /locus_tag="ctg1_2109"
                     /protein_end="162"
                     /protein_start="56"
                     /score="45.6"
                     /tool="antismash"
                     /translation="LKEIQETIAKIDPLPGAKEFLDELRTFSQVILISDTFTQFATPLM
                     EKLGWPTLFCNSLEVAENGEITGFKMRTEQSKLSTVKALQSIGFETIASGDSYNDLGMI
                     QA"
     CDS             4154..4846
                     /locus_tag="ctg1_2110"
                     /transl_table=11
                     /translation="MPGFILHLTSAKMLLNQLPDHPHFPYMIASENDFMTGSLLPDATA
                     NKNRTHFRNLLYADKMMLWPDLKRFLSSYQNQLANDLYLGYYFHLYIDKRFFKDYIPQI
                     VSFYDKEGKITDIRNEICSVLIHKSNQCISLTDYLSEKYYYGDYTKMNRYLVEKYQLPT
                     ELYPHLPQNGIEGIHSEDMNGLLSMLKKFMDLSPCAVEELTVFELSPLLEFLGKATSDF
                     LTGQELFR"
     CDS             complement(4919..6601)
                     /locus_tag="ctg1_2111"
                     /transl_table=11
                     /translation="MYQEEFKRWLAADLEDPDLKPELSRIEGNNDEIKERFAVALKFGT
                     AGLRGVLGAGTNRMNIYVIRQATQGLANWVKTQGGTQTVAISYDSRLKSDVFAKTAAGV
                     LAANGIKVRIYDALMPVPALSFATRYYQCNAGVMVTASHNPAKYNGYKAYGPDGCQMTD
                     DAAAIVYEEIQKTDVLTGAKYMSFAEGVEEGLIRFVGDDCKKALYEAIESRQVRPGLCS
                     TAGLKLVYSPLNGSGLVPVTRVLKDIGITDITFVPEQEYPNGYFTTCSYPNPEIFEALE
                     LGLKLAEETEADLMLATDPDADRVGIAMKCPDGSYELVSGNEMGVLLLDYICAGRIEKG
                     TMPEKPVAVKSIVSTPLADAVAEHYGVELRSVLTGFKWIGDQIARLEDAGEVDRFIFGF
                     EESYGYLAGPYVRDKDAVIGSMLICEMAAYYRSIGSSLKQRLEEIYAQYGRYLNKVDSF
                     EFPGLSGMDKMAAIMQGLRENPLTEIAGYKVVNVTDYQKPEETGLPAANVLIYKLENNE
                     TVIVRPSGTEPKIKIYYTTLGKNLAEAEAEKEKLAAAIEPMLV"
     PFAM_domain     complement(4952..5161)
                     /aSDomain="PGM_PMM_IV"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00408.22"
                     /description="Phosphoglucomutase/phosphomannomutase,
                     C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2111_0076"
                     /evalue="4.50E-06"
                     /label="ctg1_2111"
                     /locus_tag="ctg1_2111"
                     /protein_end="550"
                     /protein_start="480"
                     /score="26.9"
                     /tool="antismash"
                     /translation="LTEIAGYKVVNVTDYQKPEETGLPAANVLIYKLENNETVIVRPSG
                     TEPKIKIYYTTLGKNLAEAEAEKEK"
     PFAM_domain     complement(5258..5641)
                     /aSDomain="PGM_PMM_III"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02880.18"
                     /description="Phosphoglucomutase/phosphomannomutase,
                     alpha/beta/alpha domain III"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2111_0075"
                     /evalue="4.80E-18"
                     /label="ctg1_2111"
                     /locus_tag="ctg1_2111"
                     /protein_end="448"
                     /protein_start="320"
                     /score="65.5"
                     /tool="antismash"
                     /translation="GNEMGVLLLDYICAGRIEKGTMPEKPVAVKSIVSTPLADAVAEHY
                     GVELRSVLTGFKWIGDQIARLEDAGEVDRFIFGFEESYGYLAGPYVRDKDAVIGSMLIC
                     EMAAYYRSIGSSLKQRLEEIYAQY"
     PFAM_domain     complement(5678..5938)
                     /aSDomain="PGM_PMM_II"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02879.18"
                     /description="Phosphoglucomutase/phosphomannomutase,
                     alpha/beta/alpha domain II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2111_0074"
                     /evalue="6.00E-19"
                     /label="ctg1_2111"
                     /locus_tag="ctg1_2111"
                     /protein_end="308"
                     /protein_start="221"
                     /score="68.7"
                     /tool="antismash"
                     /translation="STAGLKLVYSPLNGSGLVPVTRVLKDIGITDITFVPEQEYPNGYF
                     TTCSYPNPEIFEALELGLKLAEETEADLMLATDPDADRVGIA"
     PFAM_domain     complement(6074..6481)
                     /aSDomain="PGM_PMM_I"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02878.18"
                     /description="Phosphoglucomutase/phosphomannomutase,
                     alpha/beta/alpha domain I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2111_0073"
                     /evalue="1.00E-42"
                     /label="ctg1_2111"
                     /locus_tag="ctg1_2111"
                     /protein_end="176"
                     /protein_start="40"
                     /score="145.2"
                     /tool="antismash"
                     /translation="LKFGTAGLRGVLGAGTNRMNIYVIRQATQGLANWVKTQGGTQTVA
                     ISYDSRLKSDVFAKTAAGVLAANGIKVRIYDALMPVPALSFATRYYQCNAGVMVTASHN
                     PAKYNGYKAYGPDGCQMTDDAAAIVYEEIQKT"
     CDS             complement(6746..7234)
                     /locus_tag="ctg1_2112"
                     /transl_table=11
                     /translation="MKEENTYRQTIPSSTTGRYTALTRKAMRICYAAHEGQMDKSGVPY
                     VFHPIHLAEQMETEEEICTALLHDVVEDTKWTLKELEAEGFPTGVLEAVRLLTREKDVP
                     YMAYIERLSGNQIARKVKLADLEHNSDLTRLIEVTERDLRRQEKYFLAKEFLLRQEDT"
     CDS             complement(7353..7493)
                     /locus_tag="ctg1_2113"
                     /transl_table=11
                     /translation="MKKESYEKLEMEVIAFDKIHMDTSSTSGIAVDDREDADEGIWTGY
                     Y"
     CDS             complement(7790..8986)
                     /locus_tag="ctg1_2114"
                     /transl_table=11
                     /translation="MMYDKAQCKILFQIIRVSLFDSDEFEINAEADWKLIYRISREHKI
                     HTILCRGLEKISSKDKIPEKMIGKLEELWQIERAKDAVQKYSIDEILDAFEKDKIDCVP
                     LKGIYMKEFYPDSSLRTMSDLDIFYRQGDEEKIEKVLVSKGYVFDHDGPHHDVYQRKPF
                     MNVEMHHHLTDGDPVAEKYYKDVWTTKVHLKKGYTSIYEFSWEDYYIYMLVHLAKHIKL
                     GGSGIRSIIDIKIFLDKKKEELNWDYVKEELKKLHLSQFEYWMRQLSEVWFGTEKTTPL
                     YDELTEFIVDSGTYGTIKNYHASHVVELGGKNQNLSVGKIRSKLEIIFLPYEGMQEQYL
                     YLEKFPFLLPVAWIQRIFRTIVWRKDKITSTLQSTNIEQDRLEKVKKVMDALELFESD"
     PFAM_domain     complement(8165..8899)
                     /aSDomain="NTP_transf_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14907.8"
                     /description="Uncharacterised nucleotidyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2114_0077"
                     /evalue="2.20E-55"
                     /label="ctg1_2114"
                     /locus_tag="ctg1_2114"
                     /protein_end="274"
                     /protein_start="29"
                     /score="188.0"
                     /tool="antismash"
                     /translation="EADWKLIYRISREHKIHTILCRGLEKISSKDKIPEKMIGKLEELW
                     QIERAKDAVQKYSIDEILDAFEKDKIDCVPLKGIYMKEFYPDSSLRTMSDLDIFYRQGD
                     EEKIEKVLVSKGYVFDHDGPHHDVYQRKPFMNVEMHHHLTDGDPVAEKYYKDVWTTKVH
                     LKKGYTSIYEFSWEDYYIYMLVHLAKHIKLGGSGIRSIIDIKIFLDKKKEELNWDYVKE
                     ELKKLHLSQFEYWMRQLSEVWFG"
     CDS             complement(9008..9274)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2115"
                     /sec_met_domain="PF05402 (E-value: 2.2e-18, bitscore: 63.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.8e-11,
                     bitscore: 39.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKKGYIMKELAGRYVVLPVGGEPEGFQGMIQMNVTGGFLWECL
                     SEERTKQELIDLFLEKYDASREDAEADVNTFIENLSKAGILEV"
     PFAM_domain     complement(9017..9229)
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2115_0078"
                     /evalue="3.40E-17"
                     /label="ctg1_2115"
                     /locus_tag="ctg1_2115"
                     /protein_end="86"
                     /protein_start="15"
                     /score="62.6"
                     /tool="antismash"
                     /translation="YVVLPVGGEPEGFQGMIQMNVTGGFLWECLSEERTKQELIDLFLE
                     KYDASREDAEADVNTFIENLSKAGIL"
     CDS             complement(9287..9997)
                     /locus_tag="ctg1_2116"
                     /transl_table=11
                     /translation="MYYKIADCFVKYEPNYMYMQKKIKPYEERFHGESENSCIYLGYKS
                     DAYYKKKQKMHPEITCEKLEYVYVGAEFNRKILKYGGIMIHSSAVEVDGKAYLFSAPCG
                     TGKSTHTKQWQKYFGADQAIIINDDKPVLRRLEDGWYAYGTPFSGKTDENVNKKVKLQG
                     ICMLERGENRIRQIQPAEAIPLILQQTIRPKNEKYLGKMMEIMDQLLREVPVYRMQCDI
                     SEEAVKMSYEAMKG"
     CDS             10696..11886
                     /gene_functions="other (smcogs) SMCOG1229:transposase
                     (Score: 311.4; E-value: 1.2e-94)"
                     /gene_kind="other"
                     /locus_tag="ctg1_2117"
                     /transl_table=11
                     /translation="MGRKASTINLSEDERLYLETQMRARTIQAQTVIRARILLLKAEGI
                     SVDHIADKVGMNRKSVMLCINKYLEGGVENALFDAPGRGRNAEITDDEKAWIINIACQK
                     PVNLGYSAEVWTRALLTKHINKFAEEAGHTRLSTISQSKVRTILEEADIKPNKITYYCE
                     NRDPDFDQKMHNVLLVYKQLSLQFDEKGQLIPFKEDEQVVHVLSYDEKPGIQAIANTTE
                     DLLPDENHKTVSRDYEYKRLGTISLLAGIDLQTGEAIPLVKDKHSSKEYIEFLKILDSK
                     YPETDRIRLVLDNLKVHSSEETRKYLATKPGRFEFVFTPKHGSWLNLVEGFFSKLTRQM
                     LKGIRVKTKDELVQRIYRYFDEVNEQPVVYHWKYKLEEINSSEEVVVDTLPIQKSS"
     PFAM_domain     10795..10950
                     /aSDomain="HTH_28"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13518.8"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2117_0079"
                     /evalue="2.80E-08"
                     /label="ctg1_2117"
                     /locus_tag="ctg1_2117"
                     /protein_end="85"
                     /protein_start="33"
                     /score="33.8"
                     /tool="antismash"
                     /translation="RARILLLKAEGISVDHIADKVGMNRKSVMLCINKYLEGGVENALF
                     DAPGRGR"
     PFAM_domain     11368..11751
                     /aSDomain="DDE_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13358.8"
                     /description="DDE superfamily endonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2117_0080"
                     /evalue="6.70E-26"
                     /label="ctg1_2117"
                     /locus_tag="ctg1_2117"
                     /protein_end="352"
                     /protein_start="224"
                     /score="90.9"
                     /tool="antismash"
                     /translation="LPDENHKTVSRDYEYKRLGTISLLAGIDLQTGEAIPLVKDKHSSK
                     EYIEFLKILDSKYPETDRIRLVLDNLKVHSSEETRKYLATKPGRFEFVFTPKHGSWLNL
                     VEGFFSKLTRQMLKGIRVKTKDEL"
     aSDomain        11982..12377
                     /aSDomain="TIGR00738"
                     /aSTool="tigrfam"
                     /description="rrf2_super: Rrf2 family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2118_0028"
                     /evalue="6.20E-39"
                     /identifier="TIGR00738"
                     /label="ctg1_2118"
                     /locus_tag="ctg1_2118"
                     /protein_end="132"
                     /protein_start="0"
                     /score="130.9"
                     /tool="antismash"
                     /translation="MIISTRGRYALRVMIDLAGQDPNTYTPLKEIAARQEISEKYLENI
                     LKSLVTGGLIFGLRGKGGGYKLTKKPEDYTISSILRLTEGSLAPVACLEENATECEREA
                     VCPTRPLWKKLDTLIQDYLGSVSLKDLI"
     CDS             11982..12392
                     /locus_tag="ctg1_2118"
                     /transl_table=11
                     /translation="MIISTRGRYALRVMIDLAGQDPNTYTPLKEIAARQEISEKYLENI
                     LKSLVTGGLIFGLRGKGGGYKLTKKPEDYTISSILRLTEGSLAPVACLEENATECEREA
                     VCPTRPLWKKLDTLIQDYLGSVSLKDLIDGTV"
     PFAM_domain     11988..12380
                     /aSDomain="Rrf2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02082.22"
                     /description="Iron-dependent Transcriptional regulator"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2118_0081"
                     /evalue="1.40E-35"
                     /label="ctg1_2118"
                     /locus_tag="ctg1_2118"
                     /protein_end="133"
                     /protein_start="2"
                     /score="122.5"
                     /tool="antismash"
                     /translation="ISTRGRYALRVMIDLAGQDPNTYTPLKEIAARQEISEKYLENILK
                     SLVTGGLIFGLRGKGGGYKLTKKPEDYTISSILRLTEGSLAPVACLEENATECEREAVC
                     PTRPLWKKLDTLIQDYLGSVSLKDLID"
     CDS             complement(12532..13224)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 214.1; E-value: 3.1e-65)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2119"
                     /transl_table=11
                     /translation="MSKRILIVEDEESIADLEKDYLELSGFEVEVANDGETGLRRGLAV
                     EFDLIILDLMLPGVDGFEICRQIRGQKNTPIIMVSAKKDDIDKIRGLGLGADDYMTKPF
                     SPSELVARVKAHLARYERLIGSVVEQNDVIEIRGLKIDRTARRVWVNGEERSFTTKEFD
                     LLSFLAGHPNHVYSKEELFREIWDMESIGDIATVTVHIKKIREKIEYDTSHPQYIETIW
                     GVGYRFKV"
     PFAM_domain     complement(12541..12768)
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2119_0083"
                     /evalue="1.30E-24"
                     /label="ctg1_2119"
                     /locus_tag="ctg1_2119"
                     /protein_end="228"
                     /protein_start="152"
                     /score="86.1"
                     /tool="antismash"
                     /translation="EERSFTTKEFDLLSFLAGHPNHVYSKEELFREIWDMESIGDIATV
                     TVHIKKIREKIEYDTSHPQYIETIWGVGYRF"
     PFAM_domain     complement(12883..13212)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2119_0082"
                     /evalue="7.10E-28"
                     /label="ctg1_2119"
                     /locus_tag="ctg1_2119"
                     /protein_end="114"
                     /protein_start="4"
                     /score="97.1"
                     /tool="antismash"
                     /translation="ILIVEDEESIADLEKDYLELSGFEVEVANDGETGLRRGLAVEFDL
                     IILDLMLPGVDGFEICRQIRGQKNTPIIMVSAKKDDIDKIRGLGLGADDYMTKPFSPSE
                     LVARVK"
     CDS             complement(13217..14272)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 223.2; E-value: 1.4e-67)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2120"
                     /transl_table=11
                     /translation="MKLKTKLVIVFMVVMVFPMLFTGVMTRAFVPEKATEIQQMYLIVV
                     SITAALLIIWIYRAVSVPLQKLQKAARNIKEGNLDFEIKAENDDEIGQLCRDFEEMRLR
                     LKVQAEEKVAFDRENKELISNISHDLKTPITAIKGYVEGIMDGVADTPEKMDRYIRTIY
                     NKANEMNLLINELTLYSKIDTNRIPYNFTTISAKGYFGDCAEDLSVELESKGAEFTYRN
                     FMDDDCKVIVDPEQLRRVINNIVSNSLKYTDKPKVEITMDVKDVGDFIQIELGDNGRGI
                     AAKDLPFIFDRFYRADASRNSSKGGSGIGLSIVKKIVEEHGGNIWATSEEGVGTTMYFV
                     IRKYQEVPVNE"
     PFAM_domain     complement(13247..13576)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2120_0086"
                     /evalue="1.10E-28"
                     /label="ctg1_2120"
                     /locus_tag="ctg1_2120"
                     /protein_end="342"
                     /protein_start="232"
                     /score="100.1"
                     /tool="antismash"
                     /translation="DPEQLRRVINNIVSNSLKYTDKPKVEITMDVKDVGDFIQIELGDN
                     GRGIAAKDLPFIFDRFYRADASRNSSKGGSGIGLSIVKKIVEEHGGNIWATSEEGVGTT
                     MYFVIR"
     PFAM_domain     complement(13721..13915)
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2120_0085"
                     /evalue="3.50E-14"
                     /label="ctg1_2120"
                     /locus_tag="ctg1_2120"
                     /protein_end="184"
                     /protein_start="119"
                     /score="52.7"
                     /tool="antismash"
                     /translation="KELISNISHDLKTPITAIKGYVEGIMDGVADTPEKMDRYIRTIYN
                     KANEMNLLINELTLYSKIDT"
     PFAM_domain     complement(13958..14110)
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00672.27"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2120_0084"
                     /evalue="5.40E-11"
                     /label="ctg1_2120"
                     /locus_tag="ctg1_2120"
                     /protein_end="105"
                     /protein_start="54"
                     /score="42.8"
                     /tool="antismash"
                     /translation="WIYRAVSVPLQKLQKAARNIKEGNLDFEIKAENDDEIGQLCRDFE
                     EMRLRL"
     CDS             complement(14415..15608)
                     /locus_tag="ctg1_2121"
                     /transl_table=11
                     /translation="MEKEKILFTSESVTEGHPDKMCDQISDAILDELMRQDPMSRVACE
                     TCCTTGLVMVMGEITTKAYVDIQKIVRDTVREIGYTRGKYGFDADTCGVLTTLDEQSTD
                     IAMGVDKALEAKENKMSDEDIEAIGAGDQGMMFGYASDETEEYMPYPIALAHKLALQLT
                     KVRKDGTLTYLRPDGKTQVTAEYNEDGSVKRLDAVVLSTQHDPEVSQEQIHEDIKKYVF
                     DEIIPAELVDDETKFFVNPTGRFVIGGPHGDSGLTGRKIIVDTYGGMARHGGGAFSGKD
                     CTKVDRSAAYAARYAAKNIVAAGLAKKCEIQLSYAIGVAQPTSIAVDTFGTGKLSDTKL
                     VEILRENFDFRPAGIIKMLDLRRPIYKQTAAYGHFGRNDLDLPWEKLDKVEDLKKYL"
     aSDomain        complement(14421..15590)
                     /aSDomain="TIGR01034"
                     /aSTool="tigrfam"
                     /description="metK: methionine adenosyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2121_0029"
                     /evalue="3.10E-181"
                     /identifier="TIGR01034"
                     /label="ctg1_2121"
                     /locus_tag="ctg1_2121"
                     /protein_end="396"
                     /protein_start="6"
                     /score="600.3"
                     /tool="antismash"
                     /translation="LFTSESVTEGHPDKMCDQISDAILDELMRQDPMSRVACETCCTTG
                     LVMVMGEITTKAYVDIQKIVRDTVREIGYTRGKYGFDADTCGVLTTLDEQSTDIAMGVD
                     KALEAKENKMSDEDIEAIGAGDQGMMFGYASDETEEYMPYPIALAHKLALQLTKVRKDG
                     TLTYLRPDGKTQVTAEYNEDGSVKRLDAVVLSTQHDPEVSQEQIHEDIKKYVFDEIIPA
                     ELVDDETKFFVNPTGRFVIGGPHGDSGLTGRKIIVDTYGGMARHGGGAFSGKDCTKVDR
                     SAAYAARYAAKNIVAAGLAKKCEIQLSYAIGVAQPTSIAVDTFGTGKLSDTKLVEILRE
                     NFDFRPAGIIKMLDLRRPIYKQTAAYGHFGRNDLDLPWEKLDKVEDLKKY"
     PFAM_domain     complement(14451..14870)
                     /aSDomain="S-AdoMet_synt_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02773.18"
                     /description="S-adenosylmethionine synthetase, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2121_0089"
                     /evalue="6.00E-71"
                     /label="ctg1_2121"
                     /locus_tag="ctg1_2121"
                     /protein_end="386"
                     /protein_start="246"
                     /score="236.9"
                     /tool="antismash"
                     /translation="IGGPHGDSGLTGRKIIVDTYGGMARHGGGAFSGKDCTKVDRSAAY
                     AARYAAKNIVAAGLAKKCEIQLSYAIGVAQPTSIAVDTFGTGKLSDTKLVEILRENFDF
                     RPAGIIKMLDLRRPIYKQTAAYGHFGRNDLDLPWEK"
     PFAM_domain     complement(14874..15227)
                     /aSDomain="S-AdoMet_synt_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02772.18"
                     /description="S-adenosylmethionine synthetase, central
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2121_0088"
                     /evalue="2.10E-47"
                     /label="ctg1_2121"
                     /locus_tag="ctg1_2121"
                     /protein_end="245"
                     /protein_start="127"
                     /score="160.3"
                     /tool="antismash"
                     /translation="IGAGDQGMMFGYASDETEEYMPYPIALAHKLALQLTKVRKDGTLT
                     YLRPDGKTQVTAEYNEDGSVKRLDAVVLSTQHDPEVSQEQIHEDIKKYVFDEIIPAELV
                     DDETKFFVNPTGRF"
     PFAM_domain     complement(15303..15593)
                     /aSDomain="S-AdoMet_synt_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00438.22"
                     /description="S-adenosylmethionine synthetase, N-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2121_0087"
                     /evalue="8.80E-45"
                     /label="ctg1_2121"
                     /locus_tag="ctg1_2121"
                     /protein_end="102"
                     /protein_start="5"
                     /score="151.4"
                     /tool="antismash"
                     /translation="ILFTSESVTEGHPDKMCDQISDAILDELMRQDPMSRVACETCCTT
                     GLVMVMGEITTKAYVDIQKIVRDTVREIGYTRGKYGFDADTCGVLTTLDEQS"
     CDS             complement(16300..17457)
                     /locus_tag="ctg1_2122"
                     /transl_table=11
                     /translation="MKIVTAIDSFKGSMTSMEAGRAVAEGIHRADAGAEVLVRPLADGG
                     EGTVEALTSGMNGSRQQVQVTGPLGTPVICEYGIIEASGTAVIEMAGAAGITLVPDEKR
                     NPLYTTTYGVGEVIRDAIKKGCRRFIIGIGGSATNDGGTGMLQALGYGFLDKNGNQIPF
                     GARGLKVLETITETHVLQELKECRFRIACDVTNSLCGEQGCSAVFGPQKGATPSMVVEM
                     DQWLENYAALAGKKFPKADPQQAGTGAAGGLGFAFLTFTDAVLESGIKIVLEETRLEEY
                     IREADLVITGEGQMDGQTAMGKAPIGVAGLAKKYGKTVIAFTGAAGVDAEKCNEHGIDA
                     FFPILRNVVTLEEAMKNENAKRNLADTAEQVYRLWRAGTGSVSVF"
     aSDomain        complement(16330..17454)
                     /aSDomain="TIGR00045"
                     /aSTool="tigrfam"
                     /description="TIGR00045: glycerate kinase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2122_0030"
                     /evalue="1.20E-137"
                     /identifier="TIGR00045"
                     /label="ctg1_2122"
                     /locus_tag="ctg1_2122"
                     /protein_end="376"
                     /protein_start="1"
                     /score="456.9"
                     /tool="antismash"
                     /translation="KIVTAIDSFKGSMTSMEAGRAVAEGIHRADAGAEVLVRPLADGGE
                     GTVEALTSGMNGSRQQVQVTGPLGTPVICEYGIIEASGTAVIEMAGAAGITLVPDEKRN
                     PLYTTTYGVGEVIRDAIKKGCRRFIIGIGGSATNDGGTGMLQALGYGFLDKNGNQIPFG
                     ARGLKVLETITETHVLQELKECRFRIACDVTNSLCGEQGCSAVFGPQKGATPSMVVEMD
                     QWLENYAALAGKKFPKADPQQAGTGAAGGLGFAFLTFTDAVLESGIKIVLEETRLEEYI
                     READLVITGEGQMDGQTAMGKAPIGVAGLAKKYGKTVIAFTGAAGVDAEKCNEHGIDAF
                     FPILRNVVTLEEAMKNENAKRNLADTAEQVYRLWR"
     PFAM_domain     complement(16333..17451)
                     /aSDomain="Gly_kinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02595.17"
                     /description="Glycerate kinase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2122_0090"
                     /evalue="2.00E-143"
                     /label="ctg1_2122"
                     /locus_tag="ctg1_2122"
                     /protein_end="375"
                     /protein_start="2"
                     /score="477.9"
                     /tool="antismash"
                     /translation="IVTAIDSFKGSMTSMEAGRAVAEGIHRADAGAEVLVRPLADGGEG
                     TVEALTSGMNGSRQQVQVTGPLGTPVICEYGIIEASGTAVIEMAGAAGITLVPDEKRNP
                     LYTTTYGVGEVIRDAIKKGCRRFIIGIGGSATNDGGTGMLQALGYGFLDKNGNQIPFGA
                     RGLKVLETITETHVLQELKECRFRIACDVTNSLCGEQGCSAVFGPQKGATPSMVVEMDQ
                     WLENYAALAGKKFPKADPQQAGTGAAGGLGFAFLTFTDAVLESGIKIVLEETRLEEYIR
                     EADLVITGEGQMDGQTAMGKAPIGVAGLAKKYGKTVIAFTGAAGVDAEKCNEHGIDAFF
                     PILRNVVTLEEAMKNENAKRNLADTAEQVYRLW"
     CDS             complement(17454..18056)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280:thiamine-phosphate pyrophosphorylase (Score:
                     86.3; E-value: 2.6e-26)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2123"
                     /transl_table=11
                     /translation="VIAVSNRHLCKRPFLEQIKIVCEWHPKALILREKDLTEAEYEQLA
                     GQVMKICETYKVPCILHNFWQIAVKLNCNQIHLPLPVLRQLVNQAVIQEKNQGSGTFYQ
                     IGTSVHSVEEAVEAEKLGASYLVAGHIYVTDCKKGVPPRGIRFLKEVCDAVRLPVYGIG
                     GIHFEPEQWKELAKAGAKGGCIMSGMMTLSEEEGKAE"
     PFAM_domain     complement(17493..18053)
                     /aSDomain="TMP-TENI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02581.19"
                     /description="Thiamine monophosphate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2123_0091"
                     /evalue="1.00E-38"
                     /label="ctg1_2123"
                     /locus_tag="ctg1_2123"
                     /protein_end="188"
                     /protein_start="1"
                     /score="132.6"
                     /tool="antismash"
                     /translation="IAVSNRHLCKRPFLEQIKIVCEWHPKALILREKDLTEAEYEQLAG
                     QVMKICETYKVPCILHNFWQIAVKLNCNQIHLPLPVLRQLVNQAVIQEKNQGSGTFYQI
                     GTSVHSVEEAVEAEKLGASYLVAGHIYVTDCKKGVPPRGIRFLKEVCDAVRLPVYGIGG
                     IHFEPEQWKELAKAGAKGGCIMSG"
ORIGIN
        1 tcaataatgg atcactaccg gatctcccac ctgaatcaga tcatataatt gtcctgcatc
       61 ggaatagctc atgttgatac atccatgtga tccacgataa gtataaacat caccaccgaa
      121 tgtcctctgc catgttgcat catggaatcc aacccctgaa tacgttaccc gcatccagta
      181 atctaccggt gtctcatact cataagttcc gtccggcttc aaagctcctc gtaatgtctt
      241 atttctcatc ctttcaagaa tcgtataaac accttccggg gtctgccttg ccctggtcgg
      301 aagtcccgtc acaatatccg tgctcatcag gatctgtcca tccctgacat accacatttt
      361 ctgattcgtc agatcgactt ctgcataggt tgtcccccag tcagatgcac catgggaaat
      421 cgccgtcttt ccctctacat atgccggttc acggctgacc gtatccccat tctcaatatt
      481 ggcaagcaat gctgtcagct cgctttcttc atcgatctcc caaccatagg ttcctccact
      541 cacctgagct gaccggccat ccgctgtcgt aaaagtcctt gtctttccga ctgtatcata
      601 cttttccgca aattgcttca accactcctg taccagttcc ggatgaaaag tcacagcaaa
      661 attttcatca gccgttaccc actgcgagat cactgtcccg tctactacaa ccggttcatc
      721 catctcataa gtaatccttg ctttcagata agggttcatt tgatcgcatg ctgcctgaac
      781 ttccggagaa tccttaatat atttcggtct gacatagcat cctgtatcat caagctccag
      841 ctcttctgtc aaatgggaaa ctgcatctcc gatcacttcg ttcaatgtat ctacatctac
      901 tgccgtccct tttccttcct ctcccggtac gaatttttct ccgtcaaaaa aaggagtgga
      961 agaagccggc tgcgtctgtt cacctgtcac tacattcaat gtactgatct tttcttttaa
     1021 cttttcctta tcataagata cactgaccgg aatttccagc gtctgctctc gatcaaatgc
     1081 aaccggccac agccagaaat tctgctcccg taacaactta cctgccgcat catccgcctc
     1141 atattcaaca ccgatttccg aaccttgaat ctgatctttc acattttccc ggccttttat
     1201 ctccaacaca taattttttg tatcttcttt taaatagtcc tcaatttctg ccctgttcgc
     1261 ataagaaaaa tcttttccat taatctccgt attcggcaga caatgaaaat agaaatacgc
     1321 tgctgttcca atgtaaactg cagcagttgt tcctgcaatc cctccaagcg tgatcaacaa
     1381 tggttttctc catttgtggg gcttctcagt ttcctctgac acctgctgtt ctgacgtttc
     1441 tgtctctgtt acttctatat cgtttccgtc aaaagtttcc ttttccattc actttctcct
     1501 catcctttgt atccggttct ttccggcagc attctcttta ccacaggcag aatgcctctc
     1561 tctattagac tacatttttg caaaaaaaga tagattaaat taaattttta taaaattttc
     1621 ttttcatcaa gaatgattta aaaagtttta tactctcaaa gaggcaggat ggaaaaacat
     1681 tccattcctg cctcttttca ttcagactca ctctatattc ccgttatctt tatgcctctg
     1741 agaaaaactt ttctttcact tcttctaccg gcatttcttt tcctgtgaat aattcaaatg
     1801 ctgctgctcc ctgccataac agcattccaa ttccaccgat cgccgcacgg cagcctgcct
     1861 cttttgcttt cttcacaagt aaagtctcta atggattgta tacaacatct gcaactgcca
     1921 gttccggacg aaggacatcc tccggtaccg gaatcacatc ctgaagcgga gccattcccg
     1981 cacgggtagc attgataagg atatcgcttt ctgcgatcac agctcgcaat ttctccgtat
     2041 tatccaaatc ttctatgtac acctttccga tcgtcggaac agcttttttg atcttctcca
     2101 cggttttctc accattggca aaaaactcat cttttctgtt gaagatcgca atttcagcta
     2161 ctccgtccaa cgctgcctgg actgcgatcg ctgtcgctgc tccgccagtt ccaagcacca
     2221 cgatcttctg atcttttact tctacactat gctctttcag attgcgtaca aaacctgtcc
     2281 catccgtgat atgaccggtc attgtaccat cttcttccac aacgaccgta ttgcacgcac
     2341 cgatcaattc ggcagccggt gataaacggt caaccagtct cgctacctcc gtcttacatg
     2401 gcatcgttac attgaatcca cctacattca gagtacggaa cgcctccagt gctttagctg
     2461 tctgccctac attcacatca aatgcaagat aagccgcatc aatcccaagc ttttcaaaac
     2521 tataattctg cattgccggt gatcctgaat gacctaccgg tgatccgatc aaagcgtata
     2581 atctcgtatg tccgttaatt ctcttttcca ttacaaatac ctcccaaaat caaaacgtag
     2641 gtacagtata acatctcttt ttcaaaactt caatactgta aagtgtaaaa tttttatcgc
     2701 tttaacgcgt taaattttta actttttcca ctttacgttg tccgctgtca acctatttta
     2761 tgacactttc tattgcattc caaaagatgc aagcttcata tcctcatcaa acgctaatgt
     2821 ataatgaatc tctacattct catatgtcgc tgtgacataa gcaaccgctg cattcacacc
     2881 acgcttggaa atcgttgtcg tggatatatc tcccattgac ttaaatgcac cccagtcatc
     2941 tgaaactttt tcttttgcct ctgacagacg ctcttctgtc atgatctctt tcatcttatc
     3001 agctgaaaca tcctgcagac tttcataatc atccgcatta atatatccta tgactttttc
     3061 tgcctgactt tttacggttg cttcatcaaa aagagtactg tcctcaagcg aacctgtcct
     3121 cggcatcatc cagtaggttg ccactgaagc caaaaccagt atgaccgcaa tgatcacaat
     3181 atttctggtc ttcttctttt tttcagccgc tgtctttttt tctttaaact tagggttata
     3241 taatttctgg ttcatctgct ccctcttatc tctctgatct cccggatcac atttctctgt
     3301 tccgaccggt cactcaaatc tcatttttct attttttgaa gtcctgctat aattccgaga
     3361 ttatttcatt gcttttttga tcgcagtaag aagctcgtca taactttcat atgccggaat
     3421 ttcaggataa tctgctttga tcttctctgt acttctgaac aggaatcctg cactgcttgc
     3481 ctggatcatt cccagatcat tataggaatc tccactggcg atcgtctcaa atccgatgga
     3541 ctgtaacgcc tttactgtac tcagcttgga ctgttccgta cgcatcttaa atccggtgat
     3601 ttcaccattc tccgccactt caagactatt acaaaacagt gtcggccatc ccagcttctc
     3661 catcagcgga gttgcaaact gcgtaaatgt atcactgatc aggatcacct ggctgaaggt
     3721 acgaagttca tccaaaaact cctttgcacc cggcagcgga tcaatctttg cgatcgtctc
     3781 ctgaatctct ttcagaccca gaccatgctc tcttaagatt ccaagtctcc agttcatcag
     3841 cttatcatag tccggctcat cacgtgtcgt tcttttcagc tccgggatac cgcttgcttc
     3901 cgcaaatgcg acccagatct ccggtactaa aactccttct acatcaagac aggtaatata
     3961 cataactttc ttcctccatt tattcaactt tattcgcttt gttgctttac cttggtacat
     4021 ccattatctg aacattgatt tcattctacc acactgcttt ctgctgtgca atttataatt
     4081 ggcaatcacg ggattttgat tgtatacttg aaatagtata cagctaaatc accaaagaaa
     4141 ggatctatac tttatgcctg gttttatttt acatctgact tccgctaaaa tgcttctgaa
     4201 ccaattaccg gatcaccctc attttcccta tatgattgct tccgaaaatg atttcatgac
     4261 cggttctctg ctgcccgatg ccactgccaa caagaaccgg actcatttcc gcaatctgct
     4321 ttatgccgac aaaatgatgc tttggccgga cctgaaacgt tttctttcca gctatcagaa
     4381 tcagcttgca aatgatctgt atctcggcta ctattttcat ctttatattg ataaacgctt
     4441 ttttaaagat tatattcccc agatcgtatc cttttacgat aaagaaggaa agattaccga
     4501 catccgcaat gagatctgct ctgtcctgat ccataaatcg aatcagtgca tttctctgac
     4561 cgattactta tctgaaaaat actattacgg tgattacact aaaatgaacc ggtatctggt
     4621 tgaaaaatat caactgccga cagaacttta tccccacctt ccccaaaacg gcattgaggg
     4681 aatccattcc gaggatatga acggtctgct ttctatgcta aaaaaattta tggatctttc
     4741 gccttgtgca gtggaagaac tgaccgtctt tgaactttct ccattactgg aatttttagg
     4801 aaaagcaaca tctgactttc ttacaggaca agagcttttc agatagaaga aagaaaagca
     4861 gactttggat tcgatgatct aaagtctgct tcgttggtaa atagattctc ttttcttctt
     4921 ataccagcat cggttcgatt gctgctgcca gtttctcttt ttcagcctca gcctcagcaa
     4981 ggttcttacc aagcgttgta taataaatct tgatcttcgg ttctgttcct gaaggccgga
     5041 caatgactgt ctcgttattc tccagcttat agatcagaac attcgctgcc ggaagacctg
     5101 tctcctccgg tttctgataa tccgttacat tcacaacctt atatcctgca atctctgtca
     5161 gtggattctc acgaagtccc tgcatgatag ctgccatctt atccattcca ctgagtcccg
     5221 ggaactcaaa gctgtctacc ttgttgagat aacgtccata ctgggcataa atctcttcca
     5281 gtctctgctt cagtgaactt ccgatacttc tatagtaagc tgccatctca cagatcagca
     5341 tggaaccgat cacggcatct ttgtcacgta catatggtcc tgccagatat ccgtagctct
     5401 cttcaaatcc aaagataaaa cgatcgacct ctccggcatc ttccagtctg gcgatctgat
     5461 caccgatcca cttaaatcct gtcagaacgc tgcggagttc tactccgtaa tgctctgcaa
     5521 ccgcatctgc cagtggagta gaaacgatgg acttcacagc caccggcttc tccggcatcg
     5581 ttcccttctc aatgcgacct gcacatatgt agtccaaaag aagaactccc atttcatttc
     5641 cgctgacaag ctcataagaa ccatccgggc atttcattgc aattcctaca cggtctgcat
     5701 ccgggtctgt cgccagcatc aaatctgcct ctgtctcttc tgcaagcttc aatcccagct
     5761 ccaatgcctc gaaaatctcc gggttcggat aactgcaggt tgtgaaataa ccattcggat
     5821 actcctgctc cggaacaaac gtgatatctg taatgccgat atctttcaat acccgggtaa
     5881 caggaacaag ccctgaacca ttcaacgggc tatacaccag tttcagtcct gctgtactgc
     5941 aaagacccgg acgcacctga cgagactcaa tcgcttcata aagagccttc ttgcagtcat
     6001 ctcccacaaa acggatcaga ccttcctcaa cgccctctgc aaaggacata tatttagctc
     6061 cagtcagaac atccgtcttc tgaatctctt cgtatacgat cgctgctgca tcatccgtca
     6121 tctgacagcc atccggtccg tatgctttgt aaccattata ttttgccgga ttgtgggacg
     6181 ctgtcaccat aactcctgca ttacactgat aataacgtgt cgcaaaagag agtgccggaa
     6241 ccggcatcaa tgcatcataa attcttactt tgatcccatt ggcagcaaga acacctgcag
     6301 cagtctttgc aaatacatca ctcttgagac ggctgtcata actgatcgca acagtctgcg
     6361 ttccaccctg cgtcttaacc cagtttgcaa gtccctgcgt agcctgtcgt atcacataaa
     6421 tattcatgcg gtttgttccg gctccaagta caccgcgaag tccagctgtt ccaaacttca
     6481 gtgcaactgc aaaacgttcc ttgatctcat cattatttcc ttcgattctg gataactccg
     6541 gcttcagatc cggatcttca agatctgctg ccagccaacg cttaaactct tcctgataca
     6601 tacttatcac tcctacctac tttttctact agcttgtccg agacaacacc aaccataata
     6661 taccatgatt cttatttaac atcaataaaa ctccggcatt ttaaaccgga gttttgatga
     6721 aatttattct catttttcga cgtttttatg tatcttcctg tcggagcaga aactcttttg
     6781 caagaaaata tttctcctgt cttctcaaat ccctctctgt cacttcaatc agacgggtca
     6841 gatcgctgtt atgttccaga tctgccagtt taacttttct cgcaatctga tttccactca
     6901 gtcgttcaat ataagccata tatggtacat ctttctctct ggtcagcagc ctgactgcct
     6961 ccagcacacc tgtcggaaac ccctctgcct caagttcttt cagtgtccac ttcgtatctt
     7021 ccaccacatc atgcagcaat gcagtacaga tttcctcttc tgtctccatc tgctccgcaa
     7081 gatggatcgg atgaaagaca tatggtacac cgcttttgtc catctgtccc tcgtgtgcgg
     7141 cataacagat ccgcatcgcc tttcttgtca gggcggtata acggcctgtg gtggatgacg
     7201 gaatagtttg tctataggta ttttcttctt tcatggtatt gctcccgttc ttcatgaaat
     7261 gctatttcag ttcaaagaag ctctgataat aaatcatcag agcttctttt ggttcacagc
     7321 attctatatg cggtcttatc taaaggtaga ttttaataat atcctgtcca gattccttca
     7381 tcagcatcct ccctatcatc aactgctata ccacttgtag agcttgtatc catatggatc
     7441 ttatcgaaag caattacctc catttcaagt ttctcataac tctctttttt catgttgcac
     7501 atctcctcct aaataaaata ttatattcaa agtataaatt attttacagt tactaatact
     7561 tggtaatgta agcgttccat tctcatatgt atacaacctt gtcaggagct ttcactgtga
     7621 tatcaattag tttctgcaat ccgtaggcat caaagtcggg ggcttttgac cccgacatca
     7681 catatacatt atatccaaca gtggctacat tatcaagagc ctcttcccat aaaactttag
     7741 ctcgccattt ttaacagtta ctgcacaatt tttatctaat tcggaacggt taatcgcttt
     7801 caaacaattc cagagcatcc atcacttttt ttactttctc caatctatct tgttctatat
     7861 ttgtagactg cagggtcgaa gtgattttgt ccttacgcca tactattgtt ctgaaaatcc
     7921 gttgtatcca tgccaccgga agaagaaatg gaaatttctc cagatataaa tactgttctt
     7981 gcattccttc atatggtaaa aaaataattt ccagtttgct gcgtatcttt cctacagaaa
     8041 gattttgatt ttttccaccc aattcaacaa catgacttgc atgataattt tttatagttc
     8101 cataagttcc actgtctaca ataaactctg tcaattcatc atacaaaggt gtagtttttt
     8161 ctgtgccaaa ccagacttca cttaattgcc gcatccaata ttcaaattga cttaaatgca
     8221 gtttttttag ttcttctttc acataatccc aattcagttc ttccttcttt ttatcaagga
     8281 aaatcttgat atcaattatg gagcggattc cactgcctcc aagttttata tgctttgcaa
     8341 gatgcacaag catataaata tagtaatctt cccatgaaaa ttcataaatg gaagtatatc
     8401 cttttttaag atgaactttg gtcgtccata catctttata atatttttca gcgacaggat
     8461 ctccatctgt taaatgatga tgcatctcca cattcataaa tggctttcgc tgataaacat
     8521 catgatgtgg accgtcgtga tcaaatacat accccttaga caccagtact ttttctattt
     8581 tttcctcatc accttgtctg taaaaaatat ccagatctga catggttcta agactggaat
     8641 ccggataaaa ctctttcata taaattcctt ttagaggcac gcaatctatc ttatcctttt
     8701 caaatgcatc caatatctca tcaatggagt acttctgcac agcatctttt gccctctcga
     8761 tctgccacaa ttcttctagt tttccgatca tcttttccgg tattttatct tttgaagaaa
     8821 tcttttccaa tcctctacag agaatcgtat ggattttatg ctcccggctg atccgataga
     8881 tcagtttcca gtctgcctcc gcatttattt caaattcatc actgtcgaac aaactaaccc
     8941 gaatgatctg aaacaaaatt ttgcactgtg ctttatcata catcatctat ttttctcctc
     9001 gtaatgatca gacttccagt atccccgctt tactaagatt ttctataaaa gtatttacat
     9061 ctgcttctgc atcttctcta cttgcatcat atttctccaa aaacagatcg atcaattcct
     9121 gttttgtcct ctcttctgag agacattccc ataaaaatcc tccggtcaca ttcatctgta
     9181 tcattccctg aaatccctct ggctcgcctc ctaccggaag aactacatat cttccggcaa
     9241 gttctttcat aatatatcct ttttttaact tcattttgct ccttctttat cccttcattg
     9301 cttcatatga catctttaca gcttcttctg atatatcaca ctgcattcta tagaccggaa
     9361 cttctctaag aagctgatcc ataatctcca tcatctttcc aaggtatttt tcattctttg
     9421 gacggatcgt ctgctgaaga atcagaggga ttgcctctgc cggctgaatc tgccgtatcc
     9481 gattctctcc ccgttcaagc atacagattc cctgaagttt tactttctta tttacattct
     9541 catcggtttt cccactaaaa ggtgttccat atgcatacca tccatcttcc agtcgtctta
     9601 gaaccggttt atcatcatta attataatcg cctgatctgc accaaaatat ttttgccact
     9661 gcttcgtatg tgtcgatttt cctgtaccac atggagcaga aaataaatag gcttttccat
     9721 ccacttcgac cgcagatgag tgaatcatga taccaccgta ttttaaaatt tttctattaa
     9781 attcagctcc aacataaacg tattctagtt tttcacaggt aatttctgga tgcatttttt
     9841 gctttttttt ataatatgca tccgacttat accctaaata tatacatgaa ttttcacttt
     9901 ctccatgaaa ccgctcttca tatggtttta ttttcttttg catatacata taattcggct
     9961 catatttcac aaaacaatca gcaatcttat aatacatcct tttcccctct catctgcttt
    10021 tgttacaatc acatttgaaa atctgtgcct gtccattctg tttccatccc gcaaaagtct
    10081 gtccttcttt ttcttctgcg gttacagtaa tcttatgatg tcagggtcaa aaggtctgac
    10141 accacgtgtg cctgcacact ggtggtagaa tgaccttgag gcccgccccg atatgagcat
    10201 aaaagtgggg cgtaagcacc atgatatgcg aatagcgggt aggattgtgg gagtgcgtag
    10261 cacgaaacaa tccgttggca tcattgttgg gggcttttga ccccaacatc atcttatcat
    10321 tatactgtcc tcttgtatac tcttttccat caactgcatt ctgctttttg tctgattcgg
    10381 aactttttgt acttttgcac aagttagtca attatatttt tctttttcct acaaattcac
    10441 tttgaaatag ggtattataa taagatgtcg gggtcaaaag cccccgacta tgatacctac
    10501 ggattgttac gcactacgtg ctcccacaat cctacccaac attcgcatat cgtggtgctt
    10561 acgccccact tttatgctca tattggggcg ggtcacaagg tcattctacc actagtacaa
    10621 aagtttttaa ataaatggac tatatttctt ttctgtagta tactgttctc atcaaatcaa
    10681 aaggagcatt aaactatggg aagaaaagca tccactatta atcttagcga ggacgaacgt
    10741 ttatatcttg aaactcagat gcgtgcaaga acaattcaag cccagacagt aattcgggca
    10801 agaattttac tactcaaagc agaaggtatt tcagttgacc atattgcaga caaagtagga
    10861 atgaatcgca aaagcgtcat gctctgtatc aataaatacc ttgagggtgg tgtggaaaat
    10921 gctctgtttg atgcacccgg tcgtggcagg aatgctgaaa taaccgatga tgaaaaagcc
    10981 tggataataa atatcgcctg tcagaagcct gtcaatcttg gatattcagc agaagtatgg
    11041 acgcgtgctc ttcttacaaa acatattaat aaatttgccg aagaagcagg tcatacaagg
    11101 ttgtcaacaa tcagtcagtc aaaggtccgc acaatactgg aagaagcgga tattaagcct
    11161 aacaaaataa cttattactg cgaaaatcgt gaccctgatt ttgaccagaa aatgcataat
    11221 gttcttcttg tatataaaca attgtcttta cagtttgacg agaagggaca gctcattccg
    11281 tttaaggagg atgaacaggt tgtacatgta ctttcctatg atgaaaaacc cggaattcag
    11341 gcaattgcca ataccacaga agacctcttg ccggatgaaa atcacaagac ggtcagccgt
    11401 gattatgaat ataaacgtct tggaactatt tcactgcttg ctggaatcga cttacaaaca
    11461 ggggaggcaa ttccgcttgt aaaagataaa cacagcagca aggaatatat tgagtttcta
    11521 aaaatacttg attcaaaata tccggagact gaccggattc gtctggtatt ggataatctg
    11581 aaagttcatt cttcagagga aacccgaaaa taccttgcga caaagccggg aagatttgaa
    11641 tttgtgttta ctcccaagca tggttcatgg ttgaatcttg ttgagggatt ctttagtaaa
    11701 ctcacacgtc agatgctaaa aggcatacgt gtaaaaacta aggatgaact tgtgcagcgt
    11761 atctatagat acttcgatga agtaaacgaa caacctgtcg tatatcactg gaagtataag
    11821 cttgaagaaa ttaattcaag tgaagaggtg gtggttgata cgttgccaat tcaaaagtcc
    11881 agttaattaa taacggttat actagtgtgc aagcacacgt ggtgtcagac cttttgaccc
    11941 tggtatcata ataataacga atcaacgtag gaggaataat tatgattata tctaccaggg
    12001 gaagatatgc acttcgtgtc atgattgatc tggccggaca agatccgaat acttatacgc
    12061 cactcaagga aattgcagca cggcaggaga tttctgaaaa atatcttgaa aatattctca
    12121 agtctcttgt taccggtggc ctgatctttg gacttcgcgg aaaaggcggt ggctataagc
    12181 tcactaagaa accggaggat tatactattt cttcaattct ccgtctcaca gagggatcac
    12241 ttgcaccggt ggcatgtctt gaagaaaatg cgactgaatg tgaaagggaa gcggtttgcc
    12301 ctacccgccc actttggaaa aaactggata cactgatcca ggattatctt ggcagtgtct
    12361 cactgaaaga cctgattgat gggactgtct gacaaaaaag aacgttactc ccgaatgact
    12421 gcacatccat ggagtaacgt tctttctttt ctataactat ctttatgcca gacttccgcc
    12481 tgtcttatac aaaattttcc gctctgcttt cctctctctt tttaacttct cttatacctt
    12541 gaagcggtat ccgacccccc aaattgtctc aatgtactgt ggatgagatg tgtcatattc
    12601 aatcttttca cggatctttt taatatgtac ggtaactgtt gcaatatctc ctattgactc
    12661 catatcccaa atctcacgga ataattcttc ctttgaataa acatggtttg gatgtcctgc
    12721 cagaaacgaa agcagatcga actcttttgt tgtaaaggaa cgttcctcac cgttcaccca
    12781 tacacgtctc gctgtccggt cgatcttaag tccgcggatc tctatcacat cattctgttc
    12841 cacaacactt ccgatcagac gctcatatct tgcaagatgg gctttcacgc gtgcgaccag
    12901 ctcgcttgga ctaaacggct tcgtcatata atcatccgca ccaagtccca gtccacggat
    12961 cttgtcaata tcatctttct tcgctgaaac cataataatt ggagtatttt tctgcccccg
    13021 gatctgacgg cagatttcaa atccgtcaac tcccggcagc atcagatcta aaataatcag
    13081 gtcaaattct acggcaagtc ctctccgaag acctgtctct ccgtcatttg ctacttctac
    13141 ttcaaatcca ctcagctcca gataatcttt ctccagatct gcaatgcttt cttcatcttc
    13201 cacgatcaaa atacgtttac tcattcaccg gtacctcctg atacttcctt attacaaaat
    13261 acatcgtagt accaacgccc tcttcgctgg tagcccagat atttccgcca tgctcctcca
    13321 cgatcttctt cacgatcgaa agtccgatac cacttcctcc ttttgaagaa tttcttgaag
    13381 catccgcacg atagaaccgg tcaaagataa acggcagatc ctttgccgca atccctcttc
    13441 cattatctcc cagctctatc tggataaaat ctcccacgtc ctttacatcc atcgtaatct
    13501 ccactttcgg tttatctgta tacttcagcg aatttgatac gatattattg atgactcttc
    13561 ttaactgttc cggatctacg atcactttac agtcatcatc cataaagttt cggtatgtaa
    13621 actctgcccc ttttgactcc agctccacac tcagatcttc tgcacagtct ccaaaataac
    13681 cttttgcaga gatcgttgtg aaattatatg gaatcctgtt cgtatcgatc ttggagtaaa
    13741 gggtcagctc attgatcaga agattcatct cattagcctt attataaatg gttctgatgt
    13801 atctgtccat cttttccggt gtatctgcca caccatccat aattccttcc acataacctt
    13861 tgatcgctgt gatcggagtc ttcagatcat gtgaaatatt actgatcagt tccttatttt
    13921 cccggtcaaa cgcaaccttt tcctctgcct gcaccttcaa ccgaagacgc atttcctcaa
    13981 aatccctgca aagctgcccg atctcatcat cattttctgc tttaatctca aaatccagat
    14041 ttccttcttt gatattcctt gccgctttct gtaatttttg cagcggcact gataccgcac
    14101 gataaatcca tatgatcaac aatgctgccg tgatggatac gacgatcaga tacatctgct
    14161 ggatctccgt tgccttttcc ggtacaaatg cccttgtcat cactccggta aaaagcatcg
    14221 gaaataccat gaccaccata aatacgataa cgagttttgt cttaagcttc atttgcagct
    14281 cctttccgaa aatcgagtat gattaacgaa aggtgcctga accttttcag gagatcagac
    14341 accttctttt gatacttctg cttattttac agattctaca aatatttctt tcatttttga
    14401 gatattcttt cactttacag atatttcttt aaatcttcta ccttgtcaag tttctcccac
    14461 ggaagatcca ggtcattacg tccaaaatgt ccgtaagcgg ctgtctgctt gtagatcggt
    14521 cttctcagat ccagcatctt aatgattcct gccgggcgga aatcaaaatt ctcacgaagg
    14581 atctcaacca gctttgtatc agataacttt cctgtaccaa atgtatcaac tgcgatagaa
    14641 gtcggctgtg ccacaccgat cgcataagaa agctggatct cacatttctt tgcaagtcct
    14701 gctgctacaa tattctttgc tgcataacgt gctgcataag ctgcagaacg gtctaccttt
    14761 gtgcagtctt ttcctgaaaa tgctccgcca ccgtgacgtg ccattccacc ataagtatca
    14821 acaatgatct tacgtcctgt cagtccactg tctccgtgag gtccgccaat tacaaaccgg
    14881 cctgtcggat ttacaaagaa tttcgtctca tcatctacca gctctgccgg gatgatctca
    14941 tcgaatacat actttttgat atcctcatga atctgctcct gagatacttc cgggtcatgc
    15001 tgcgtagaaa gcacaactgc atccagacgc tttacagaac catcttcatt gtactctgca
    15061 gttacctgag tctttccgtc cggacgcagg taagtcagcg ttccgtcttt gcgaacttta
    15121 gtaagctgaa gtgcaagctt atgtgccagt gcgatcggat atggcatata ctcttctgtc
    15181 tcatcagaag cataaccgaa catcattccc tgatctcctg ctccaatggc ttcgatatct
    15241 tcatctgaca tcttattttc ttttgcttcc agagccttat caactcccat tgcaatatct
    15301 gttgactgct catccaatgt tgtgagtaca ccgcaggtat ctgcatcaaa gccatatttt
    15361 cctcttgtat atccgatctc gcgaactgta tcacgaacga tcttctggat atctacatat
    15421 gcttttgtag tgatctctcc cataaccata acaagacctg ttgtacagca tgtctcacat
    15481 gcaacacggc tcatcggatc ctgacgcatt aactcatcca gaatcgcatc tgaaatctga
    15541 tcacacatct tatccggatg tccctctgta actgactcag atgtaaataa aatcttttcc
    15601 ttttccataa gttctccttt cactcacttt ctcttctgct tactgctttc acgtaatatc
    15661 gccttcgtcc gcctgacctg ccccgcggaa cctcgattcc gcttcgcttc atctcggtcg
    15721 cgggcggcct gctcttcttc cggtacaggt tttctgactg cctccgcctg acctgccccg
    15781 cggaacctcg attccgcttc gcttcatctc ggtcgcgggc ggcctgccct tcttccggta
    15841 caggttttct gactgcctcc gcctgacctg ccccgcggaa cctcgattcc gcttcgcttc
    15901 atctcggtcg cgggcggcct gcctataccc tggcaactct ctgtctgctc acgcaagcgt
    15961 ggcagccaat gagttgtcag ggtgcaggtc aggctttaat acgcgaaaac agtccgcata
    16021 aggcggactg tcaatctatc gtaacaatcc tcttattgtt cgagtaactc gctcaggttg
    16081 gcaccttcct ttataatgtg gggttgccgc agcttcttag atcctttgta tctccactgc
    16141 tctgaataag agaaagtttc tttattaaat tagtatttta ctttcgtatc agactataca
    16201 acgcattgtc tattatgtca atatagttta gaaaactttc attatatttt cttatctatg
    16261 acttcccagt aaccatactt tgggaatcca tttcacaagt caaaataccg acacgctgcc
    16321 tgtacctgcc cgccacaacc ggtacacctg ctctgccgta tctgccaggt ttctctttgc
    16381 attttcattt ttcatggctt cttccagtgt aaccacattt cgcagaatcg gaaaaaatgc
    16441 atcgattcca tgttcattgc atttttctgc atccactccg gctgccccgg taaatgcgat
    16501 cacagtcttt ccgtatttct ttgcaagtcc ggctactcct atcggtgctt tccccatggc
    16561 ggtctgtccg tccatctgtc cttctccggt aatcaccaag tctgcttctc tgatgtactc
    16621 ttccagccgg gtttcttcta aaacaatctt gatccctgac tctaaaactg catcggtaaa
    16681 tgtcagaaat gcaaatccca gtcctccggc tgccccggtt cctgcctgct gcggatctgc
    16741 tttcgggaat ttttttcctg ccagtgccgc ataattttcc agccattgat ccatctccac
    16801 aaccatggac ggagttgccc ctttctgcgg accaaagaca gcactgcacc cctgctcacc
    16861 gcataggctg ttcgttacat cacacgctat acggaatctg cactccttta attcctgcag
    16921 aacatgcgtc tccgtgatcg tttctaaaac tttcagccct ctcgctccga agggaatctg
    16981 gtttccattt ttatcgagga atccgtatcc aagtgcctgc agcatccctg ttccaccgtc
    17041 attggttgca cttccaccaa tgccgataat gaatcgcctg cagccttttt tgatggcatc
    17101 ccggatcact tcaccgacac catatgttgt cgtatagagc ggatttcttt tttcatctgg
    17161 aacgagtgtg atcccggccg cacctgccat ctcaatcacg gctgtcccgg aagcttcaat
    17221 aattccatat tcgcatatga ccggtgttcc cagtggtcct gttacctgta cctgctgtct
    17281 gctcccgttc attcccgacg tcagtgcttc taccgttcct tcaccaccat ctgccagcgg
    17341 tcttacgagt acttctgccc cggcatctgc cctgtggatt ccttctgcca cagcccttcc
    17401 ggcctccatg gatgtcatac tgcctttaaa cgaatctatc gctgttacaa ttttcattct
    17461 gcttttcctt cctcttctga cagcgtcatc attcctgaca taatgcagcc accctttgct
    17521 ccggctttgg cgagttcttt ccactgctcc ggctcaaaat ggatcccacc gatcccatag
    17581 accggcagcc tcactgcatc acagacttct ttcaaaaatc tgattcccct tggaggaacg
    17641 cctttcttac aatccgtcac ataaatatgg cctgccacca gataagatgc ccccagcttt
    17701 tccgcttcaa ccgcttcttc caccgagtga accgaagtcc ctatctgata aaatgttccg
    17761 ctgccctgat ttttctcctg tatcacagcc tgattcacca actgccgcag cacaggaagt
    17821 gggagatgaa tctggttaca gtttaatttt accgcaattt gccagaaatt gtgaagaata
    17881 catggaactt tatacgtttc acaaattttc attacctgtc cggccagttg ttcatactcc
    17941 gcttctgtca gatccttttc ccttaaaatc agtgctttgg gatgccattc gcatactatt
    18001 ttgatctgct caaggaacgg tcttttgcac aaatgccggt tgctgactgc gatcac
//
