LOCUS       c00001_NZ_CADI..       10900 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CADIKC010000001.1 Paraburkholderia sediminicola strain LMG 24238
            isolate LMG 24238, whole genome shotgun sequence.
ACCESSION   c00001_NZ_CADI..
VERSION     c00001_NZ_CADI..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:21:11
            Original ID  :: NZ_CADIKC010000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 183708
            Orig. end    :: 194608
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10900
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[188708:189608](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5900
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10900
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10900
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             84..2465
                     /gene_functions="transport (smcogs)
                     SMCOG1082:TonB-dependent siderophore receptor family
                     (Score: 352.5; E-value: 1.2e-106)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_169"
                     /transl_table=11
                     /translation="MLNFALRRLPFCARRIPSGRRPLSSLSNFPAYFSALVPAFAPAFI
                     APPAHAESAPADATLPAVSVTASANAVAAPRAVDPNLPASVETVTREQFDNWNVVNTED
                     VLKYMPNLAVRKRFIGDLNSIIAVRGTSNTQSARGLVYADGLLLSNLLGNSYSFPPRWS
                     MVFPDEIQQVDVIYGPFSALYPGNSLGATVLISTRMPKKFEADADVKAFTQHFGLFGVN
                     QNFNGSEASASIGDQIGKFSYRLGVNHLENTSQPLQFATLAKSSTPAKAGDTPVTGAYF
                     YNNQTNTPTAVLGVNGEGIEHTVQDQFKLKMQYDFTPTLQAAFTLGYWHQTYNSATSSF
                     LRDANGNPVYSGKVAIGGYEYTIPAAALAPSLGYSENWLYGLTLKTRNATGWNGEAIAS
                     YYDVSNSVARTANSGAPGNGPGTVIFGDGTGWKTLDLRTTYTPVTPQAGLTSHALSFGY
                     HYDNYFLDNESYNTLNWRDGAATSFANAFKGKTQTQALYAQDAWHFLPRWKLVYGVRYE
                     DWQAYGGSQALPGKAFPYSDANQHHFSPKASLSFDVTDDLTLRASIGRAYRFPTVGEMF
                     QGQINGSSIINNNPNLKPEDDLSKELTAEWAHWNGVFRFSLFQDDVKNTIFSQTDTTVI
                     PNVTNFQNIGKVRSRGVETSYSGQDVFVRGLDLLASVAYTQSKIIANAQNPATVGKYFY
                     RIPLWRANLAATYHIDERAAITLAARYSGREYNTLTNTDTNPNVFGGTSSYTVADAKFT
                     FKPTKLSEVGIGVDNIFDARYFVYHPYPGRTFYVEAKLRM"
     PFAM_domain     324..656
                     /aSDomain="Plug"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07715.17"
                     /description="TonB-dependent Receptor Plug Domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_169_0001"
                     /evalue="1.90E-14"
                     /label="ctg1_169"
                     /locus_tag="ctg1_169"
                     /protein_end="191"
                     /protein_start="80"
                     /score="54.2"
                     /tool="antismash"
                     /translation="NLPASVETVTREQFDNWNVVNTEDVLKYMPNLAVRKRFIGDLNSI
                     IAVRGTSNTQSARGLVYADGLLLSNLLGNSYSFPPRWSMVFPDEIQQVDVIYGPFSALY
                     PGNSLGA"
     PFAM_domain     1092..2456
                     /aSDomain="TonB_dep_Rec"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00593.26"
                     /description="TonB dependent receptor"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_169_0002"
                     /evalue="2.50E-54"
                     /label="ctg1_169"
                     /locus_tag="ctg1_169"
                     /protein_end="791"
                     /protein_start="336"
                     /score="186.0"
                     /tool="antismash"
                     /translation="TSSFLRDANGNPVYSGKVAIGGYEYTIPAAALAPSLGYSENWLYG
                     LTLKTRNATGWNGEAIASYYDVSNSVARTANSGAPGNGPGTVIFGDGTGWKTLDLRTTY
                     TPVTPQAGLTSHALSFGYHYDNYFLDNESYNTLNWRDGAATSFANAFKGKTQTQALYAQ
                     DAWHFLPRWKLVYGVRYEDWQAYGGSQALPGKAFPYSDANQHHFSPKASLSFDVTDDLT
                     LRASIGRAYRFPTVGEMFQGQINGSSIINNNPNLKPEDDLSKELTAEWAHWNGVFRFSL
                     FQDDVKNTIFSQTDTTVIPNVTNFQNIGKVRSRGVETSYSGQDVFVRGLDLLASVAYTQ
                     SKIIANAQNPATVGKYFYRIPLWRANLAATYHIDERAAITLAARYSGREYNTLTNTDTN
                     PNVFGGTSSYTVADAKFTFKPTKLSEVGIGVDNIFDARYFVYHPYPGRTFYVEAKL"
     CDS             2564..4057
                     /locus_tag="ctg1_170"
                     /transl_table=11
                     /translation="MSTTTAQRATSAPGAANAGYRTLWRWHFYAGLFVMPFLVVLAITG
                     TLYCFQPQIEPLLYPHRLIVEPQAMPRLTEDALLAKARAAMPADARAVTAPIASALERS
                     TEFIFRLADGEKQSVYLSPYSGEVLGTLSVEHRFMQVDRMLHRKLLLGKPGELLMELAA
                     CWTLVMIGTGIALWWPREKTTARAALVPRFSLRGRPLWKNLHVVMGIWLALGALIFVLS
                     GLPWTGSWGKQFKALATAANLGAPPGSWGGLPLRSALPGVRADKHAGTADAGAETQQGH
                     GEHSAHQANMDSMPGMVMDDLPLPLTPWAVGNTPVPQSADAHAAQALPLGHIVDLVASL
                     GVQSGYDIVLPSSATGVYTVSYFPADPKDERTLYIDQYSGTVLKDIRYGDYGAVSKAVS
                     YGTSLHMGRYFGVANQILCAVISLGLAGMAVTGFVMWWKRRPQRSLGAPSRERAAPPMR
                     GWKTGLVLLGIVFPLMGATLLAVWLADRTIFGRATRQPA"
     PFAM_domain     2633..3880
                     /aSDomain="PepSY_TM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03929.18"
                     /description="PepSY-associated TM region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_170_0003"
                     /evalue="2.00E-79"
                     /label="ctg1_170"
                     /locus_tag="ctg1_170"
                     /protein_end="439"
                     /protein_start="23"
                     /score="267.4"
                     /tool="antismash"
                     /translation="WRWHFYAGLFVMPFLVVLAITGTLYCFQPQIEPLLYPHRLIVEPQ
                     AMPRLTEDALLAKARAAMPADARAVTAPIASALERSTEFIFRLADGEKQSVYLSPYSGE
                     VLGTLSVEHRFMQVDRMLHRKLLLGKPGELLMELAACWTLVMIGTGIALWWPREKTTAR
                     AALVPRFSLRGRPLWKNLHVVMGIWLALGALIFVLSGLPWTGSWGKQFKALATAANLGA
                     PPGSWGGLPLRSALPGVRADKHAGTADAGAETQQGHGEHSAHQANMDSMPGMVMDDLPL
                     PLTPWAVGNTPVPQSADAHAAQALPLGHIVDLVASLGVQSGYDIVLPSSATGVYTVSYF
                     PADPKDERTLYIDQYSGTVLKDIRYGDYGAVSKAVSYGTSLHMGRYFGVANQILCAVIS
                     LGLAGMAVTGFVMWWKR"
     CDS             4094..4543
                     /locus_tag="ctg1_171"
                     /transl_table=11
                     /translation="MKTSRNLLLAALLCGSSVQAFAGAAATVSVSDCWIRALPGDLPSG
                     GYFKAGNTGDQPVNLTGISTEAFGMAMLHQTQSQGSTSSMAMVHQVAVPAHGSLVFAPG
                     NYHVMLEQPKQPLKIGTTIPLTFSFSDGEKVTASCAVKSASTMSQ"
     PFAM_domain     4181..4501
                     /aSDomain="PCuAC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04314.15"
                     /description="Copper chaperone PCu(A)C"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_171_0004"
                     /evalue="1.70E-27"
                     /label="ctg1_171"
                     /locus_tag="ctg1_171"
                     /protein_end="136"
                     /protein_start="29"
                     /score="95.5"
                     /tool="antismash"
                     /translation="VSDCWIRALPGDLPSGGYFKAGNTGDQPVNLTGISTEAFGMAMLH
                     QTQSQGSTSSMAMVHQVAVPAHGSLVFAPGNYHVMLEQPKQPLKIGTTIPLTFSFSDGE
                     KVT"
     CDS             4703..4966
                     /locus_tag="ctg1_172"
                     /transl_table=11
                     /translation="LNSKLSRPALIAAALAGLAATGISAAHADERVQCFGVAKAGQNDC
                     ASKTGVHGCAGEAKVDNDKGDFKTVPKGTCQKMGGKFDEQHS"
     PFAM_domain     4799..4942
                     /aSDomain="DUF2282"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10048.11"
                     /description="Predicted integral membrane protein
                     (DUF2282)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_172_0005"
                     /evalue="2.00E-21"
                     /label="ctg1_172"
                     /locus_tag="ctg1_172"
                     /protein_end="80"
                     /protein_start="32"
                     /score="75.9"
                     /tool="antismash"
                     /translation="QCFGVAKAGQNDCASKTGVHGCAGEAKVDNDKGDFKTVPKGTCQK
                     MGG"
     CDS             5001..5900
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_173"
                     /sec_met_domain="DUF692 (E-value: 5.1e-89, bitscore: 294.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMHPPVPSACAPPGIGIGLRHAHYRDFLGATPAVDWVEVHSENYF
                     GDGGFDLHVLDTVRRDLPVSLHGVGLGLGSAKQLDLAHVAKLKRLIERIEPAVVSEHLC
                     WGATSAGYLNDLLPMPLTEAALALLSVRVSELQDALGRPVLLENVSTYVRFRDDQYGET
                     AFLAELASRTGCGVLLDVNNLYVNQCNHGKDAVAAMNALAIGTIGEIHLAGHRVTDIAV
                     IDDHGSRVANEVWALYEYALQRFGTIPTLIEWDTDVPALSVLLDEAGRARDIQKTVHGG
                     RSALSPSTQYEAGNAHTA"
     PFAM_domain     5040..5825
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_173_0006"
                     /evalue="2.00E-100"
                     /label="ctg1_173"
                     /locus_tag="ctg1_173"
                     /protein_end="275"
                     /protein_start="13"
                     /score="335.4"
                     /tool="antismash"
                     /translation="GIGIGLRHAHYRDFLGATPAVDWVEVHSENYFGDGGFDLHVLDTV
                     RRDLPVSLHGVGLGLGSAKQLDLAHVAKLKRLIERIEPAVVSEHLCWGATSAGYLNDLL
                     PMPLTEAALALLSVRVSELQDALGRPVLLENVSTYVRFRDDQYGETAFLAELASRTGCG
                     VLLDVNNLYVNQCNHGKDAVAAMNALAIGTIGEIHLAGHRVTDIAVIDDHGSRVANEVW
                     ALYEYALQRFGTIPTLIEWDTDVPALSVLLDEAGRARDIQ"
     CDS             5914..6753
                     /locus_tag="ctg1_174"
                     /transl_table=11
                     /translation="MFAESLEGEQRPVLSQLQCTGRGVDYAEGRADSSGCAAEQTPGVS
                     GDGNGAANELADNLRRRIDLYRSSIRANQRTALASAYPVLLALVGEDYFDALSVVYAEA
                     HPSQSGDLNRFGAALPAFIETYEQAPRFRYFADLACLEWSLHLAYFAADANALTQVEWA
                     AIRPEELLEAKLAVHPACALIASPYAIAEIWAAHQPGGSFPANPESPTHALVVRPQWRP
                     QILVQCPAAHAAFDALQRGATLNDALDSAFAIDAEFNFTSQWRAWIAASAITGLQPF"
     PFAM_domain     6082..6282
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_174_0007"
                     /evalue="1.90E-17"
                     /label="ctg1_174"
                     /locus_tag="ctg1_174"
                     /protein_end="123"
                     /protein_start="56"
                     /score="63.4"
                     /tool="antismash"
                     /translation="DNLRRRIDLYRSSIRANQRTALASAYPVLLALVGEDYFDALSVVY
                     AEAHPSQSGDLNRFGAALPAFI"
     CDS             6877..7713
                     /locus_tag="ctg1_175"
                     /transl_table=11
                     /translation="MLDYDRFATEQGKVMQRTRQDAVDGLLPEERERLILERLRAQGRV
                     LASELAAEFQTSEHTVRRHLRELADQGHCKRVYGGALLISPAGVDASVRMHEAVDRKAC
                     LAVVAASIVRPKQIILLDTGSTNVAIAAALPDNADLTVVTNSPEACARLLNRPGFDIIL
                     VGGRIARHAAGATGATALLQIQQIKADLCFLGACAFDPDEGVAAFDAEEAELKRAMVQA
                     SSQVAIAVTSEKLMTAAPFYVAPARAVDHLFVEADVTAARRAQLAAVCDNVMVARS"
     PFAM_domain     6967..7131
                     /aSDomain="HTH_DeoR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08220.14"
                     /description="DeoR-like helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_175_0008"
                     /evalue="6.80E-13"
                     /label="ctg1_175"
                     /locus_tag="ctg1_175"
                     /protein_end="85"
                     /protein_start="30"
                     /score="48.2"
                     /tool="antismash"
                     /translation="RERLILERLRAQGRVLASELAAEFQTSEHTVRRHLRELADQGHCK
                     RVYGGALLIS"
     PFAM_domain     7171..7638
                     /aSDomain="DeoRC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00455.24"
                     /description="DeoR C terminal sensor domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_175_0009"
                     /evalue="5.30E-39"
                     /label="ctg1_175"
                     /locus_tag="ctg1_175"
                     /protein_end="254"
                     /protein_start="98"
                     /score="133.9"
                     /tool="antismash"
                     /translation="VDRKACLAVVAASIVRPKQIILLDTGSTNVAIAAALPDNADLTVV
                     TNSPEACARLLNRPGFDIILVGGRIARHAAGATGATALLQIQQIKADLCFLGACAFDPD
                     EGVAAFDAEEAELKRAMVQASSQVAIAVTSEKLMTAAPFYVAPARAVDHLFV"
     CDS             7710..8888
                     /locus_tag="ctg1_176"
                     /transl_table=11
                     /translation="MKVLANPAGTSFTKPLKERVATLGVFLANGFGIGAWAVEVPRIKE
                     SLSLSDTSLGIALFAFALGAIIAMPLAGQLAPRFGSGRATALLGAAFVIALPLPAFAPN
                     LATLCIVLLALGAANGALDVSMNGHASTIETQWKSPIMSSFHAAWSAGGLLGAATGAML
                     QKNGIGVIGALALPDVFIAVLMAAAAMLALRDLGPRAAASSSGFALPNAKVMKLALLAF
                     LCMMVEGAVADWSAVYLRATLTEAASVAAVGYSAFAFSMAACRIVGDVSVRRFGSNKVV
                     GFGGLLAAAGLALVLSLPTVLTACVGFAMVGVGLANIVPVIFSAAGRSTDTPAVGVSMA
                     ATAGYAGFLVGPPLIGLGAGLLGLRVALCVLVVATMVVCLTGGKAVRGGSAG"
     CDS             complement(8811..9704)
                     /locus_tag="ctg1_177"
                     /transl_table=11
                     /translation="MFASGGFSELLHHASHWLGAFALALLMMGVGGALERRWPADLLQS
                     RAGMRFNVAYAALYMAFAEVMRPLMAMISVALVNALGGGWVVLASRGWGALASIVIVLL
                     TFDVLEYAFHRLQHAWPVLWKLHSLHHSAAEFNITVTFRHHWLEVLLKGCLLYPVVGVL
                     FRVEPWIVGVTGIIFMFGNYFAHMNLRIDLGRFTTWVNNPQYHRLHHSNRTEHYDHNFT
                     QLLPLWDHLFGTLWVPSKHEWPATGLDDGAQPRSLLGALSWPLLSQARRVLTSTPTTHR
                     LAPRQTNNHGSHDEHA"
     PFAM_domain     complement(9003..9407)
                     /aSDomain="FA_hydroxylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04116.15"
                     /description="Fatty acid hydroxylase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_177_0010"
                     /evalue="8.60E-27"
                     /label="ctg1_177"
                     /locus_tag="ctg1_177"
                     /protein_end="234"
                     /protein_start="99"
                     /score="94.2"
                     /tool="antismash"
                     /translation="VIVLLTFDVLEYAFHRLQHAWPVLWKLHSLHHSAAEFNITVTFRH
                     HWLEVLLKGCLLYPVVGVLFRVEPWIVGVTGIIFMFGNYFAHMNLRIDLGRFTTWVNNP
                     QYHRLHHSNRTEHYDHNFTQLLPLWDHLFGT"
ORIGIN
        1 atcgctgttg ttcctgatcg cgcatttgcc gcacccgttg agggggcgcg cgatcgcctg
       61 tccaatgtat caaggaaacg ttcatgctca acttcgctct gcgaaggctg cccttttgcg
      121 cccggcgcat tccctccggc cggcggccgc tgtcgtcgct gtcgaatttc ccggcgtatt
      181 tttctgcgct agttccggcc ttcgcaccgg catttatcgc ccccccggct cacgcggaaa
      241 gcgcgcctgc cgacgccacg ctgcctgctg ttagcgtcac cgccagcgcc aatgccgtcg
      301 ccgccccgcg cgccgtggac cctaacctgc cggcctccgt cgagaccgtg acgcgcgaac
      361 agttcgacaa ctggaacgtc gtcaataccg aagacgtgtt gaagtacatg ccgaaccttg
      421 ccgtgcgcaa gcgttttatc ggcgatctga actcgatcat cgccgtacgc ggcaccagca
      481 atacgcagag cgcacgcggt ctcgtttacg cggacggcct gctgctgagc aatctgctcg
      541 gcaacagtta ttcgtttccg ccgcgttggt cgatggtgtt tcccgacgag atccagcagg
      601 tcgacgtgat ctacggaccg ttttccgcgc tctatccggg caattcgcta ggcgccacgg
      661 tactcatcag cacccgcatg ccgaagaagt tcgaagccga cgcggacgtc aaagccttca
      721 cccagcactt cggcctgttc ggtgtgaatc agaatttcaa cggcagtgag gcgagcgctt
      781 cgatcggcga tcagatcggg aagttctcgt atcgcctggg tgtgaatcac ctggagaaca
      841 cgagccagcc gctgcaattc gccacgctgg ccaagtcgag tacgcccgcg aaagccggcg
      901 acacaccggt gaccggcgcg tacttctaca acaaccagac caacacgccg actgcggtgc
      961 tcggcgtgaa cggcgaaggg atcgaacaca ccgtgcagga ccagttcaag ctgaagatgc
     1021 agtacgactt cacaccgaca ctgcaagccg ccttcacgct cggctactgg caccagacct
     1081 acaacagcgc gacgtcgagt ttcctgcgcg atgcgaacgg caatccggta tacagcggca
     1141 aagttgcgat cggcggctac gagtacacaa ttccggctgc cgccctcgct ccgagtctcg
     1201 gctacagcga gaactggcta tacggcctca cgctgaagac gcgcaacgcc accggctgga
     1261 atggcgaagc gatcgcttcg tactacgacg tcagcaacag cgtggcacgc accgcgaatt
     1321 cgggagcgcc gggcaacggc cccggcacgg tgatcttcgg cgacggcacc ggctggaaaa
     1381 cgctcgatct gcgcaccacc tacacacccg tcacgccgca agcgggcctg acgagtcacg
     1441 cgctgagctt cggctatcac tacgacaact atttcctcga caacgagagc tacaacacgc
     1501 tgaactggcg cgacggcgcg gcaacctcgt ttgccaacgc attcaagggc aagacgcaaa
     1561 ctcaggcgct gtacgcacag gatgcctggc actttctgcc gcgctggaag ctggtctacg
     1621 gcgtacggta tgaagactgg caagcctatg gcggctcgca ggcgctgccg ggcaaagcgt
     1681 tcccgtacag cgacgcgaac cagcatcatt tttcgccgaa ggcctcgttg tcgttcgatg
     1741 tcactgacga tctgactttg cgcgcatcga ttggccgcgc ctatcgcttt ccgacggtgg
     1801 gcgagatgtt ccaggggcaa atcaatggct cgtcgatcat caacaacaat ccgaatctga
     1861 agcccgaaga cgatctctct aaagagttga ccgctgaatg ggcgcactgg aacggcgtgt
     1921 tccgcttctc gctgtttcag gacgacgtga agaacacgat cttcagtcag accgatacga
     1981 ccgtgattcc gaacgtgacg aatttccaga acatcggcaa ggtgcgctcg cgtggcgtcg
     2041 aaacgagcta ctcgggacag gatgtattcg tgcgcggcct cgatctgctg gcgagcgtgg
     2101 cgtacacgca gtcgaagatc atcgcgaacg cgcagaaccc ggcgacggtc ggcaagtact
     2161 tctatcggat tccgctgtgg cgcgcgaatc tcgccgcgac gtatcacatc gacgaacgtg
     2221 cggcgatcac gctcgccgcg cgctactccg gccgtgaata caacacgctc accaataccg
     2281 acaccaatcc caatgtattc ggcggcacca gttcgtacac ggtggcggac gcgaaattca
     2341 cgttcaagcc gacgaagctg agtgaagtcg gtatcggcgt cgacaacatc ttcgacgcgc
     2401 gctacttcgt ctatcacccg tatccgggcc gcacgtttta cgtcgaagcg aagttgcgta
     2461 tgtgaacacg cgattggcat gcgcggtttg cgctcacgag ttgcaaacca gcgcatgcag
     2521 cgctgcgcac ccgatcgacc catttctgct tcaggaggat tgaatgtcca ccaccaccgc
     2581 acaacgcgcg acctcggcac caggcgccgc gaacgccggc taccggacgc tctggcgctg
     2641 gcacttttac gcaggactct ttgtgatgcc gtttctggtc gtgctcgcga tcaccggcac
     2701 gctgtattgc ttccagccgc aaatcgaacc gctgctttac ccgcaccgcc tgatcgtcga
     2761 accgcaagcc atgcccaggc tgaccgaaga cgcattgctc gccaaagccc gcgcggcgat
     2821 gcctgccgac gcgcgcgcgg tgacggcacc cattgcgagc gcactggagc gcagcaccga
     2881 gttcattttt cgcctcgccg acggcgaaaa acagagcgtc tatctgagcc cgtacagcgg
     2941 cgaagtattg ggcacgctga gcgtcgagca ccgcttcatg caggtggacc gcatgcttca
     3001 ccgcaagctg ctgctcggca aaccaggtga attgctgatg gaattggccg cgtgctggac
     3061 gctagtgatg atcggcaccg gcatcgcact ctggtggccg cgtgagaaga ccaccgcacg
     3121 cgcggcgctg gtgccgcgct tctcgctgcg aggacgtccg ctctggaaga atcttcatgt
     3181 cgtgatgggt atctggctcg cgctcggtgc gctcatcttc gtgctgagcg gtctgccgtg
     3241 gacaggctca tggggtaagc agttcaaagc gctcgcgacc gccgctaatc ttggcgcgcc
     3301 gccgggttcg tggggtggct tgccgttgcg ttctgccctg cccggcgtgc gtgctgacaa
     3361 gcatgcgggt actgcggacg caggcgccga aacgcagcag ggccacgggg aacacagcgc
     3421 gcaccaggcg aacatggact cgatgccggg catggtgatg gacgatctgc ccttgccact
     3481 cacgccgtgg gctgtcggca acacgccagt gccgcaatcc gccgatgcgc acgcggcgca
     3541 agcgctgccg ctcggacaca tcgttgacct cgtcgcatcg ctgggtgttc agagcggcta
     3601 cgacatcgtg ctgccttcat ccgcgacagg cgtctacacc gtctcgtact ttcccgccga
     3661 cccgaaagac gagcgcacgc tgtacatcga ccaatacagc ggcacggtgc tgaaagacat
     3721 ccgttacggc gactacggcg cggtgtcgaa ggccgtgtcg tacggcacgt cgttgcatat
     3781 gggccgctat ttcggcgtcg ccaatcagat tctctgcgct gtgatttcgc ttggcctcgc
     3841 gggaatggct gtgaccggct tcgtgatgtg gtggaagcgc cggccgcagc gctcgctcgg
     3901 cgcaccctcg cgcgaacgcg ccgcaccgcc gatgcgtggc tggaaaaccg gtctcgttct
     3961 gctcggcata gtctttccat tgatgggcgc cacgctactc gcagtgtggc ttgccgaccg
     4021 tactattttt ggccgcgcta cgcggcaacc tgcttaacgc ctcatttccg ccgctaaaaa
     4081 caaggaacac atcatgaaga cgtcacgcaa ccttctcctc gccgccttgc tgtgcggatc
     4141 atccgttcag gccttcgccg gcgccgcggc aaccgtgagc gtatcggatt gctggatccg
     4201 cgcgttgccg ggtgacctgc catcgggcgg ctatttcaag gccggcaata cgggcgatca
     4261 accggtcaat ctcaccggca tcagcactga agctttcggc atggccatgc tgcatcagac
     4321 gcaaagccag ggaagcacgt cttccatggc gatggtccat caggtggcgg tgcccgcgca
     4381 cggctcgctc gtctttgcac cgggcaacta tcacgtgatg ctggaacagc cgaaacagcc
     4441 gctcaagatc ggcacgacga tcccgctgac gttctcgttc agcgacggcg agaaagtcac
     4501 cgcctcctgt gccgtgaaaa gcgcgagtac gatgagccag taacatgccg gataattcat
     4561 gcggcaggct taaaatcggc ttacgtatgg ccccggcgcc acgaatcagg cgcaccgtcc
     4621 cagccccgaa gcagccgata gcgaagcgac ggttgaaatg gtgcggcgag taatccatcg
     4681 ccgcttactc aggagaagca aattgaactc gaaacttagc cggccggcat tgatcgccgc
     4741 ggccctcgca ggactcgcgg ccaccggcat cagcgcagcg catgcggacg agagggttca
     4801 gtgctttggc gtcgccaagg ccggccagaa cgactgcgcg agcaagaccg gtgtgcacgg
     4861 ttgcgccggt gaggccaagg tcgacaacga caaaggcgac ttcaagaccg tgccgaaagg
     4921 aacctgccag aagatgggcg gcaagttcga cgaacagcat tcctgatgcc catgcggcgc
     4981 tcctgtgcca gtcggggccg atgatgcatc cccccgttcc ttctgcctgc gcgccgcccg
     5041 gcatcggtat cggtttgcgt catgcccatt accgcgactt cctcggtgct acgccggcgg
     5101 tcgactgggt cgaggtgcac agtgaaaact atttcggcga cggcggcttc gatttgcacg
     5161 tgctcgacac cgtgcgacgc gacctgcccg tcagtttgca cggggttggt ctcgggcttg
     5221 gctcggcgaa acagctcgac ctcgctcacg ttgcgaagct caaacgtctg atcgagcgaa
     5281 tcgagccggc tgtcgtctct gagcatcttt gctggggcgc gacatcggct ggctatctga
     5341 acgatctttt gccgatgccc ttgactgagg cggcgctcgc gctgctctcc gtgcgtgtca
     5401 gcgaactaca ggacgcgctc ggccggccgg ttctattgga aaacgtctcc acctacgttc
     5461 gattccgcga cgatcagtac ggcgagacgg catttcttgc cgaactcgcg tcacgcacgg
     5521 gttgtggcgt attgctcgac gtgaacaacc tgtatgtgaa ccaatgcaat catggaaagg
     5581 acgccgtcgc ggccatgaac gcgctggcga tcggcacgat tggtgaaatt catcttgctg
     5641 gtcatcgcgt gacggacatc gccgtcatcg acgatcacgg ctcacgtgtc gcgaacgaag
     5701 tctgggcgct ttatgagtac gcactgcagc ggttcggtac gataccgacg ctgatcgagt
     5761 gggataccga tgtaccggcg ttaagcgttt tactcgacga ggcaggtcgc gcacgcgata
     5821 tccagaaaac cgttcacggc gggcgatcgg cactcagccc ttcgactcaa tacgaagccg
     5881 gcaatgcgca caccgcttga gtcactgcag cgcatgtttg ccgaatcgct tgaaggcgaa
     5941 cagcggcctg tgctttcgca actgcaatgc acggggcgtg gagtcgatta cgcggaaggt
     6001 cgcgcggaca gttctggatg cgccgctgaa caaacacccg gcgtcagcgg cgatggcaat
     6061 ggcgccgcca acgaactcgc ggacaatctg cgccgacgca tcgacctcta tcggagtagc
     6121 attcgcgcca atcagcggac cgcactcgcg agtgcgtatc cagtcctgtt agcgctagtc
     6181 ggcgaagact acttcgatgc gttgtcagtg gtttacgcag aagcccatcc gtcacagagc
     6241 ggcgacctca atcgcttcgg cgcagcgcta ccggctttca tcgaaaccta cgaacaagcc
     6301 ccccgtttcc gctatttcgc cgacctcgcg tgtctcgagt ggtcgctgca tctggcctac
     6361 tttgccgccg acgctaacgc gctcacgcaa gtggaatggg ccgccatccg ccccgaggag
     6421 ttgctcgaag cgaaactggc tgtgcatccc gcctgcgcgc tcatcgcttc accctatgcg
     6481 attgccgaga tctgggcagc gcaccagcca ggcggctcct ttccggcaaa tcccgagtca
     6541 ccgacccatg cactggtcgt gcgaccacaa tggcggccgc agatactcgt tcaatgcccc
     6601 gccgcacatg ctgctttcga tgccttgcaa cgcggagcga cgctcaatga cgcgctcgac
     6661 tcggcgtttg caatcgatgc cgaattcaat ttcacgtcgc aatggcgcgc gtggatcgca
     6721 gcctcggcga ttacaggcct ccagcccttt taagcagacc gcagaccgcc cagccggcgc
     6781 cagtgccggc gccagtgcct taacaacctg ccgaacctgt ccatccagaa gaatttcgac
     6841 cgcaccgttg ccctgtccgc tcgtttacgt taaattatgc tcgattatga tcgtttcgca
     6901 accgagcagg gtaaagtcat gcaacgaacg cgacaggacg cagtggacgg gcttctgccc
     6961 gaggaacggg agcggctgat tctggaacgg ctgcgggcac agggccgcgt attggcatcc
     7021 gaactcgctg ccgaattcca aacatctgaa catacggtcc gccgccactt gcgcgagctg
     7081 gccgatcagg gccattgcaa gcgcgtgtat ggcggcgccc tgctgatctc gcctgccggc
     7141 gtagacgcct cggtccgcat gcacgaagcc gtggatcgca aggcctgcct cgccgtcgtc
     7201 gctgcgtcca tcgtccggcc caagcagatc attttgctgg acaccgggtc gaccaacgtc
     7261 gcgattgccg cggcactccc ggacaacgcc gatctaaccg tcgtgacgaa ctcgcccgag
     7321 gcttgcgcgc ggctcctgaa ccggccgggc ttcgacatca ttcttgtcgg cggccgcatc
     7381 gcgcggcacg cagccggcgc gaccggcgcc acagccttgc tgcagatcca gcagatcaag
     7441 gccgacctct gctttctggg tgcgtgcgcg ttcgatccag acgaaggcgt cgccgcgttc
     7501 gacgctgaag aggccgaact caaacgggcg atggtgcagg caagcagcca ggtcgccatc
     7561 gccgtcactt cggaaaaact gatgactgct gcgccgtttt acgttgcgcc ggcgcgcgcc
     7621 gtggaccacc tgttcgtcga agcggatgtg acggccgcgc ggcgtgccca actcgcagcg
     7681 gtgtgcgaca acgtgatggt ggcgcgctca tgaaagtact cgctaatccg gccggcacat
     7741 cgttcacgaa accgctcaag gagcgggtcg ccaccctcgg cgtgtttctc gccaatggat
     7801 tcgggatcgg cgcctgggca gtcgaagtgc cgcgcatcaa ggaaagcctg tcgctcagcg
     7861 acacgtcgtt ggggatcgcg ttgttcgcct tcgcgctagg ggccatcatt gcgatgccgc
     7921 tggccggaca gctggcgccg cgcttcggca gcggccgggc caccgcgctg ctcggcgctg
     7981 cgtttgtcat cgcgctgccg ctgcccgcct tcgcaccgaa cctggcgacg ctgtgtatcg
     8041 tgctcctcgc gctcggcgca gcgaacggcg cgctcgacgt ctcgatgaac ggccacgcca
     8101 gcacaatcga aacgcagtgg aagtcgccca tcatgtcgtc gtttcatgcg gcgtggagtg
     8161 cgggcggcct gctcggcgcg gcgacgggcg ccatgcttca gaaaaacggt attggcgtaa
     8221 tcggcgctct cgcgctgccg gacgttttca tcgccgtcct catggccgct gcagcgatgc
     8281 tggcattgcg tgatctcggt ccgcgcgcgg ccgcgtcctc gagtggcttc gcattgccca
     8341 acgccaaagt gatgaagctt gcgctgctcg cgttcctttg catgatggtg gaaggcgcgg
     8401 tggctgactg gagcgcggtg tatttgcgcg ctaccttgac cgaagcggcc agcgtcgcgg
     8461 cggtcggcta ttccgcgttt gcattctcga tggcggcttg ccgcatcgtc ggcgatgtgt
     8521 ccgtgcggcg cttcggttcg aacaaggtgg tcggcttcgg cggcctgctg gcggcggccg
     8581 gactcgcgct ggtgttgagc ctgccgaccg tgctcacggc ttgcgtgggc tttgccatgg
     8641 tcggcgtcgg tctcgcgaat atcgtcccgg tgattttcag cgcggcgggc cgctcgaccg
     8701 atacgccggc tgttggtgtt tcgatggcgg ccaccgcggg ttatgccggt tttttggtgg
     8761 gtccgccgtt gatcggactc ggtgcaggtt tgcttggctt gcgcgtggcg ctatgcgtgc
     8821 tcgtcgtggc taccatggtt gtttgtttga cggggggcaa ggcggtgcgt ggtgggagtg
     8881 ctggttagaa cacgccgggc ttgcgaaagc agcggccagc tcagcgcgcc cagcagtgaa
     8941 cgcggttgcg cgccgtcgtc cagaccggtg gccggccatt cgtgcttcga gggcacccag
     9001 agggtgccga acaggtgatc ccacagcggc agtaattgcg tgaagttgtg gtcgtaatgc
     9061 tcggtgcgat tcgagtgatg caggcgatgg tattgcggat tgttgaccca cgtcgtgaag
     9121 cgccccaggt cgatgcgcag attcatatgc gcgaagtaat tgccgaacat gaaaatgatc
     9181 ccggtcacgc cgacgatcca cggctcgacc ctgaacagca cgccgaccac tggatagagc
     9241 aggcatccct tgaggagcac ctcgagccag tgatgcctga acgtcaccgt gatattgaac
     9301 tcggcggcac tgtggtgcag tgaatgcagc ttccacagca caggccatgc atgctgcaag
     9361 cggtgaaacg catactccag cacatcgaac gtcaatagta cgattacgat ggacgccaac
     9421 gcgccccatc cccgcgaggc cagcacgacc cagcctccgc cgagcgcatt gactaatgcg
     9481 acactgatca tcgccatgag cggccgcatg acttccgcga atgccatata cagcgccgcg
     9541 taggcgacgt taaagcgcat cccggcgcgc gattgcaata agtcggccgg ccagcggcgc
     9601 tccagtgccc cgcccacgcc catcatcagc agggcgagcg cgaaggcgcc cagccagtgg
     9661 ctcgcgtggt gcagcagttc agaaaatccg cccgatgcaa acatgtgatt tcccagtcaa
     9721 tacggtacgc tcaatcgcct ggccgcccaa cctggcccgc gcagggtcga gaacattggc
     9781 ccatgacctg cggcgcgaac tggcacgctt acacgatcat attctgcaaa ccgaagttcg
     9841 tcagcaggaa gccgatgtcc gcgatgaatt agccgagaca cattggctgc cggacgaacc
     9901 ggtacgcgcg tgaccagcga catgtccact gtcacgcatg aggccgccac gagcaacagc
     9961 agtgtgatgc gtgtgggcgc cgcggcagtt tcgcacgcgt tacccggcat ggtgtgggcg
    10021 ctcactggag agtcggtgtc atggtgcgct cactgcgaaa tacgaaggat ttgcgacgcc
    10081 agctgcgaaa agcatggcgc caggtccccg ggtgtcgccg cgtggcaata cacgcctacc
    10141 ggctgcttcg agttgtagca gcgcggtagc gaatcgggtg tattcgccat gcatttgaga
    10201 acgtcctggc ccaactcgtt atcggggcct gcgggttgca ctagctgcgg gcccaagccg
    10261 agcgtgaaca catagatgtt gttgttgcgt gcgtccgctg ccatcgcttc gagcaggttg
    10321 cgtgaggctc gattgacatt ctgataggtg acggccgccg tgacaacgcg cggactattc
    10381 gtgatgatcg gaaaggtcgt gtcggtcgga ttgtgcgcat tgtagtaggc gggaagtgac
    10441 gggatgaaac tgctcgaatc gccctccaga tccgagtcgt aacacggcga actaaacgct
    10501 gtctgcaact gatcgaagcg ccacagcccg ctcatcttgc ctttactgtc gggcgacgct
    10561 atcgtgccaa cgaggttgtt acacgccttg gccttcttcg caaacgtaaa cgccgacgca
    10621 aagctattcg gcgcaccatc ggaaaagaac acgatcacgc gtagactcga cggattctgc
    10681 aacttgttca tctgattacg cgcattccag aacgcttccg aggaattggt gctgccagag
    10741 aagctatatt tctggatttg cgacgtcatc gtcgcgcgct cgaaaccacg tgagctgtcc
    10801 agtttgaacg gcgtgtcgat gatagtgccg taagcgaaat gcatcagggc gacccggtcg
    10861 ttcgtgatgt caaagctgtt caggaacgag atggcgttcg
//
