LOCUS       c00004_NZ_CABK..       20564 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKNR010000009.1 Butyrivibrio crossotus isolate MGYG-HGUT-01319,
            whole genome shotgun sequence.
ACCESSION   c00004_NZ_CABK..
VERSION     c00004_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:47:40
            Original ID  :: NZ_CABKNR010000009.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 19947
            Orig. end    :: 40511
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20564
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[29947:30511](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10564)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20564
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20564
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(551..1153)
                     /locus_tag="ctg4_25"
                     /transl_table=11
                     /translation="MQKIKICGIRRAADIEIVNKYRPDYIGFIFYKKSKRYISEADAME
                     LRKRLLPEIKTVGVFVNEKPEIVAEYLNDGVIDIAQLHGTEPEEDILFIKKMTGRPVIK
                     AVSVETQSDCEKYNESGADYILLDNGKGGTGKCFDWKLIGNVTKPFFLAGGINESNIDE
                     AIAISPYAVDVSGGVETDGFKDEDKIRKIINKCRKEL"
     PFAM_domain     complement(572..1141)
                     /aSDomain="PRAI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00697.24"
                     /description="N-(5'phosphoribosyl)anthranilate (PRA)
                     isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_25_0001"
                     /evalue="6.20E-47"
                     /label="ctg4_25"
                     /locus_tag="ctg4_25"
                     /protein_end="194"
                     /protein_start="4"
                     /score="159.9"
                     /tool="antismash"
                     /translation="KICGIRRAADIEIVNKYRPDYIGFIFYKKSKRYISEADAMELRKR
                     LLPEIKTVGVFVNEKPEIVAEYLNDGVIDIAQLHGTEPEEDILFIKKMTGRPVIKAVSV
                     ETQSDCEKYNESGADYILLDNGKGGTGKCFDWKLIGNVTKPFFLAGGINESNIDEAIAI
                     SPYAVDVSGGVETDGFKDEDKIRKIIN"
     CDS             complement(1156..1932)
                     /locus_tag="ctg4_26"
                     /transl_table=11
                     /translation="MILDEIAGKTKERIAKLKEITTMEELEKKAFSMEINNDFPFEKAL
                     SKKGLSFICEVKKASPSKGVIAENFPYLEIAKEYENAGADAISCLTEPFYFKGSNDYLK
                     EIAKEVKIPVLRKDFTVDRYMVYEAKIMGASAILLICAILTEAEIKEYSELAGELGLSV
                     LIEAHTEKEVETALRYGRIIGVNNRNLKTFEVDINTSLRLRNMVPKDYLYVSESGIKNA
                     EDIKRLYENGTDAVLIGETLMRSADKKNTIAALRGI"
     PFAM_domain     complement(1168..1926)
                     /aSDomain="IGPS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00218.23"
                     /description="Indole-3-glycerol phosphate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_26_0002"
                     /evalue="9.60E-82"
                     /label="ctg4_26"
                     /locus_tag="ctg4_26"
                     /protein_end="255"
                     /protein_start="2"
                     /score="274.0"
                     /tool="antismash"
                     /translation="LDEIAGKTKERIAKLKEITTMEELEKKAFSMEINNDFPFEKALSK
                     KGLSFICEVKKASPSKGVIAENFPYLEIAKEYENAGADAISCLTEPFYFKGSNDYLKEI
                     AKEVKIPVLRKDFTVDRYMVYEAKIMGASAILLICAILTEAEIKEYSELAGELGLSVLI
                     EAHTEKEVETALRYGRIIGVNNRNLKTFEVDINTSLRLRNMVPKDYLYVSESGIKNAED
                     IKRLYENGTDAVLIGETLMRSADKKNTIAAL"
     CDS             complement(1934..2947)
                     /locus_tag="ctg4_27"
                     /transl_table=11
                     /translation="MINEAIIKLINKENLTEDMAKKVMDEIMSGETDPVLISSYLTALT
                     MKGETVEEITASAKGMRAAGTHLLTDKETFEIVGTGGDGSNSFNISTTASFIIAAAGVP
                     VTKHGNRAASSKSGAADCLEALGVNILADEKVSKKCLDEADICFLHAQKYHSAMKYVAP
                     IRKKLGFRTVFNILGPLTNPANASMQLMGVFSEKFVESLAHVLYNLGVKRAMVVYGEDG
                     MDEISASAPTKVCEVMDGEFKSYEITPEQFSLTRCTKEELTGGTGEENAEISKAVLNGE
                     KSGRRTAVVINAGAALYVAGKAESIKSGIRLAEELIDNGAAMRKLEQFVKLSNGEA"
     aSDomain        complement(1955..2926)
                     /aSDomain="TIGR01245"
                     /aSTool="tigrfam"
                     /description="trpD: anthranilate phosphoribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_27_0001"
                     /evalue="4.90E-123"
                     /identifier="TIGR01245"
                     /label="ctg4_27"
                     /locus_tag="ctg4_27"
                     /protein_end="331"
                     /protein_start="7"
                     /score="408.6"
                     /tool="antismash"
                     /translation="KLINKENLTEDMAKKVMDEIMSGETDPVLISSYLTALTMKGETVE
                     EITASAKGMRAAGTHLLTDKETFEIVGTGGDGSNSFNISTTASFIIAAAGVPVTKHGNR
                     AASSKSGAADCLEALGVNILADEKVSKKCLDEADICFLHAQKYHSAMKYVAPIRKKLGF
                     RTVFNILGPLTNPANASMQLMGVFSEKFVESLAHVLYNLGVKRAMVVYGEDGMDEISAS
                     APTKVCEVMDGEFKSYEITPEQFSLTRCTKEELTGGTGEENAEISKAVLNGEKSGRRTA
                     VVINAGAALYVAGKAESIKSGIRLAEELIDNGAAMRKLEQFVK"
     PFAM_domain     complement(1982..2731)
                     /aSDomain="Glycos_transf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00591.23"
                     /description="Glycosyl transferase family, a/b domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_27_0004"
                     /evalue="2.30E-95"
                     /label="ctg4_27"
                     /locus_tag="ctg4_27"
                     /protein_end="322"
                     /protein_start="72"
                     /score="319.1"
                     /tool="antismash"
                     /translation="ETFEIVGTGGDGSNSFNISTTASFIIAAAGVPVTKHGNRAASSKS
                     GAADCLEALGVNILADEKVSKKCLDEADICFLHAQKYHSAMKYVAPIRKKLGFRTVFNI
                     LGPLTNPANASMQLMGVFSEKFVESLAHVLYNLGVKRAMVVYGEDGMDEISASAPTKVC
                     EVMDGEFKSYEITPEQFSLTRCTKEELTGGTGEENAEISKAVLNGEKSGRRTAVVINAG
                     AALYVAGKAESIKSGIRLAEELIDNGAA"
     PFAM_domain     complement(2753..2938)
                     /aSDomain="Glycos_trans_3N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02885.19"
                     /description="Glycosyl transferase family, helical bundle
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_27_0003"
                     /evalue="1.40E-17"
                     /label="ctg4_27"
                     /locus_tag="ctg4_27"
                     /protein_end="65"
                     /protein_start="3"
                     /score="63.3"
                     /tool="antismash"
                     /translation="EAIIKLINKENLTEDMAKKVMDEIMSGETDPVLISSYLTALTMKG
                     ETVEEITASAKGMRAAG"
     CDS             complement(2953..3525)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249:carbamoyl phosphate synthase small subunit
                     (Score: 143.7; E-value: 1.1e-43)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_28"
                     /transl_table=11
                     /translation="MILLVDNYDSFSYNLYQLTGEIEPDIKVIRNDEMTVKEIKLLNPD
                     LIIISPGPGRPENAGICIDIIKYFAGRIPILGVCLGHQAICKAFGATVSYAKELMHGKT
                     SVINADTDSVIFKGFDNKISVARYHSLAAVKETLPDCLKITAETDDGEIMAVEHKEYPV
                     YGLQFHPESILTKDGKRMMENFINSRR"
     aSDomain        complement(2965..3525)
                     /aSDomain="TIGR00566"
                     /aSTool="tigrfam"
                     /description="trpG_papA: glutamine amidotransferase of
                     anthranilate synthase or aminodeoxychorismate synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_28_0002"
                     /evalue="5.50E-69"
                     /identifier="TIGR00566"
                     /label="ctg4_28"
                     /locus_tag="ctg4_28"
                     /protein_end="187"
                     /protein_start="0"
                     /score="229.8"
                     /tool="antismash"
                     /translation="MILLVDNYDSFSYNLYQLTGEIEPDIKVIRNDEMTVKEIKLLNPD
                     LIIISPGPGRPENAGICIDIIKYFAGRIPILGVCLGHQAICKAFGATVSYAKELMHGKT
                     SVINADTDSVIFKGFDNKISVARYHSLAAVKETLPDCLKITAETDDGEIMAVEHKEYPV
                     YGLQFHPESILTKDGKRMMENFIN"
     PFAM_domain     complement(2968..3519)
                     /aSDomain="GATase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00117.30"
                     /description="Glutamine amidotransferase class-I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_28_0005"
                     /evalue="1.30E-54"
                     /label="ctg4_28"
                     /locus_tag="ctg4_28"
                     /protein_end="186"
                     /protein_start="2"
                     /score="185.0"
                     /tool="antismash"
                     /translation="LLVDNYDSFSYNLYQLTGEIEPDIKVIRNDEMTVKEIKLLNPDLI
                     IISPGPGRPENAGICIDIIKYFAGRIPILGVCLGHQAICKAFGATVSYAKELMHGKTSV
                     INADTDSVIFKGFDNKISVARYHSLAAVKETLPDCLKITAETDDGEIMAVEHKEYPVYG
                     LQFHPESILTKDGKRMMENFI"
     CDS             complement(3506..4993)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 313.3; E-value:
                     5.9e-95)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_29"
                     /transl_table=11
                     /translation="MYPTPEEAKKIIATGDYKRIPVTMELNSDMVTPVMAVKRLKKVSH
                     HCFMLESAEADKKWGRYTFLGFDPTLELTCQDGVLKIKSGFEIIEKVTHPMEYIRKIIK
                     DNKTPVLEGLPPFAGGLVGYFSYDYIKYSEPSLKLSAKDEESFKDVDLMLFDKIICFDN
                     YRQKIILIVNVRTENFDTSYNKGVMELENMKKLLLEGEMEENRPLQLKSDFRYLFDKEQ
                     YCEMVKKGKRHIFEGDIFQIVLSNRVEADIEGSLFDTYRVLRTTNPSPYMFYFSSDDVE
                     IAGASPETLVKLENGELHTFPLAGTRKRGADTEEDLRLEKELLQDEKELAEHNMLVDLG
                     RNDIGRISRIGSVEVERYMEIQRYSHVMHIGSTVRGIIRDDMDALNAVDSILPAGTLSG
                     APKLKACELICELENNKRGIYGGAIGYIDFTGNLDTCIAIRLAFAKNGKVFVRSGAGIV
                     ADSVPENEFEECINKAKAVMNALKEAEGGIDNDITCR"
     aSDomain        complement(3551..4909)
                     /aSDomain="TIGR00564"
                     /aSTool="tigrfam"
                     /description="trpE_most: anthranilate synthase component I"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_29_0003"
                     /evalue="2.20E-161"
                     /identifier="TIGR00564"
                     /label="ctg4_29"
                     /locus_tag="ctg4_29"
                     /protein_end="481"
                     /protein_start="28"
                     /score="535.8"
                     /tool="antismash"
                     /translation="DMVTPVMAVKRLKKVSHHCFMLESAEADKKWGRYTFLGFDPTLEL
                     TCQDGVLKIKSGFEIIEKVTHPMEYIRKIIKDNKTPVLEGLPPFAGGLVGYFSYDYIKY
                     SEPSLKLSAKDEESFKDVDLMLFDKIICFDNYRQKIILIVNVRTENFDTSYNKGVMELE
                     NMKKLLLEGEMEENRPLQLKSDFRYLFDKEQYCEMVKKGKRHIFEGDIFQIVLSNRVEA
                     DIEGSLFDTYRVLRTTNPSPYMFYFSSDDVEIAGASPETLVKLENGELHTFPLAGTRKR
                     GADTEEDLRLEKELLQDEKELAEHNMLVDLGRNDIGRISRIGSVEVERYMEIQRYSHVM
                     HIGSTVRGIIRDDMDALNAVDSILPAGTLSGAPKLKACELICELENNKRGIYGGAIGYI
                     DFTGNLDTCIAIRLAFAKNGKVFVRSGAGIVADSVPENEFEECINKAKAVMNAL"
     PFAM_domain     complement(3575..4336)
                     /aSDomain="Chorismate_bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00425.20"
                     /description="chorismate binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_29_0007"
                     /evalue="3.50E-87"
                     /label="ctg4_29"
                     /locus_tag="ctg4_29"
                     /protein_end="473"
                     /protein_start="219"
                     /score="292.3"
                     /tool="antismash"
                     /translation="KEQYCEMVKKGKRHIFEGDIFQIVLSNRVEADIEGSLFDTYRVLR
                     TTNPSPYMFYFSSDDVEIAGASPETLVKLENGELHTFPLAGTRKRGADTEEDLRLEKEL
                     LQDEKELAEHNMLVDLGRNDIGRISRIGSVEVERYMEIQRYSHVMHIGSTVRGIIRDDM
                     DALNAVDSILPAGTLSGAPKLKACELICELENNKRGIYGGAIGYIDFTGNLDTCIAIRL
                     AFAKNGKVFVRSGAGIVADSVPENEFEECINK"
     PFAM_domain     complement(4487..4909)
                     /aSDomain="Anth_synt_I_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04715.15"
                     /description="Anthranilate synthase component I, N terminal
                     region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_29_0006"
                     /evalue="7.20E-30"
                     /label="ctg4_29"
                     /locus_tag="ctg4_29"
                     /protein_end="169"
                     /protein_start="28"
                     /score="104.3"
                     /tool="antismash"
                     /translation="DMVTPVMAVKRLKKVSHHCFMLESAEADKKWGRYTFLGFDPTLEL
                     TCQDGVLKIKSGFEIIEKVTHPMEYIRKIIKDNKTPVLEGLPPFAGGLVGYFSYDYIKY
                     SEPSLKLSAKDEESFKDVDLMLFDKIICFDNYRQKII"
     CDS             complement(5337..6548)
                     /locus_tag="ctg4_30"
                     /transl_table=11
                     /translation="MGFPGTFFVNVNGGHIMDYTDVIIIKGPVETLSFFSERLAETFYT
                     ELNKNVIAWDMKKPLESRHFIENIREKAVLITFNFIGLSGESQFMAEGTDGKETSVWDY
                     YGIKKVCIMVDHPLYYRDQLEMINDCMLYCIDRQHVDFIRRYYPGKKVDFLPLAGTSLD
                     EGGQKRDIDVFFAGNYVNIKPLEDRINMLDKDNREFCYSMIEDLKTNTGKGIDEVIEEH
                     VRADIPDITREDMLMVTNKMMVIDLYIRSYFRQKIICNLAENGIKVHIIGKDWEKAGCK
                     KPENLVLIGQRDSLECLRYMKRSKVSVNIMPWFKDGVHDRFFNGMAQGSVVVSDSSLYI
                     DEIAKDGVEYLRFSLDNMQEIPDIVNSAVHRDDIAKQGHMLVCSGHLWRHRAVEIDNNL
                     KKYH"
     PFAM_domain     complement(5364..5603)
                     /aSDomain="Glyco_trans_1_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13524.8"
                     /description="Glycosyl transferases group 1"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_30_0008"
                     /evalue="8.70E-07"
                     /label="ctg4_30"
                     /locus_tag="ctg4_30"
                     /protein_end="395"
                     /protein_start="315"
                     /score="29.4"
                     /tool="antismash"
                     /translation="DGVHDRFFNGMAQGSVVVSDSSLYIDEIAKDGVEYLRFSLDNMQE
                     IPDIVNSAVHRDDIAKQGHMLVCSGHLWRHRAVEI"
     CDS             complement(6697..7878)
                     /locus_tag="ctg4_31"
                     /transl_table=11
                     /translation="MIVSDSVKYIGVDDTDIDLFESQYLVPDGVSYNSYVILDDKIAVM
                     DTVDERKTDEWFSNLTEVFEDRHPDYLVISHLEPDHSSNIERLAVRYPDMKLVGNAKTF
                     QMLPQFFDMDFSERSIVVKEGEELSLGTHKLVFYMAPMVHWPEVMVTYEATEKILFSAD
                     GFGKFGAIELTKDKDWACEARRYYFNIVGKYGGPVQQLLKKAAGLDVNMICPLHGPVLK
                     DNLGYYIGLYDTWSRYEPENKGVLIAYASIHGNTAKAAHELADMLKKAGEDKVVVSDLS
                     REDMAEVIEDAFRYDRMILCAASYDGGVFPCMQDFLLRLQSKAYQNRTVGMVENGSWAP
                     CAARVMRNIVDTFKNITVVEPVVTIKSTVKESDKAALSSLAQAIYEAADKTVE"
     PFAM_domain     complement(7387..7788)
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00753.29"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_31_0009"
                     /evalue="7.40E-05"
                     /label="ctg4_31"
                     /locus_tag="ctg4_31"
                     /protein_end="164"
                     /protein_start="30"
                     /score="22.9"
                     /tool="antismash"
                     /translation="SYNSYVILDDKIAVMDTVDERKTDEWFSNLTEVFEDRHPDYLVIS
                     HLEPDHSSNIERLAVRYPDMKLVGNAKTFQMLPQFFDMDFSERSIVVKEGEELSLGTHK
                     LVFYMAPMVHWPEVMVTYEATEKILFSADG"
     CDS             complement(7920..8645)
                     /locus_tag="ctg4_32"
                     /transl_table=11
                     /translation="MRVIICDDDEYIRQRLHDNIRLAFKSMRKSGYQGLLECDEYDNGK
                     DLLEDEGEKDLVFLDIEMPGADGISVGRALKQDDSDVLIAYVTSHTEFLDDAMSFCVFR
                     YISKPLNQERIVKCICDAFNILCKRRINVVIDEGNCVYRKVNTYNIVMVEKDSRRLKLY
                     MKNGEVIRVMGTINDFLIGLNPLMFVMCHRSFIINLKYVSRIDKNTVYLCGDKYVAYLS
                     RNRYTSIKEAFINYVEKSI"
     PFAM_domain     complement(7947..8219)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_32_0011"
                     /evalue="7.10E-14"
                     /label="ctg4_32"
                     /locus_tag="ctg4_32"
                     /protein_end="233"
                     /protein_start="142"
                     /score="51.9"
                     /tool="antismash"
                     /translation="RKVNTYNIVMVEKDSRRLKLYMKNGEVIRVMGTINDFLIGLNPLM
                     FVMCHRSFIINLKYVSRIDKNTVYLCGDKYVAYLSRNRYTSIKEAF"
     PFAM_domain     complement(8292..8639)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_32_0010"
                     /evalue="4.30E-15"
                     /label="ctg4_32"
                     /locus_tag="ctg4_32"
                     /protein_end="118"
                     /protein_start="2"
                     /score="56.0"
                     /tool="antismash"
                     /translation="VIICDDDEYIRQRLHDNIRLAFKSMRKSGYQGLLECDEYDNGKDL
                     LEDEGEKDLVFLDIEMPGADGISVGRALKQDDSDVLIAYVTSHTEFLDDAMSFCVFRYI
                     SKPLNQERIVKC"
     CDS             complement(8647..9933)
                     /locus_tag="ctg4_33"
                     /transl_table=11
                     /translation="MDVIIMSYFLEAFVTVIFARCMYIPRFKLPIRILIYIVLYGCAAL
                     THSDNSMLNAFADVMAGVLVLGFAYSGDPADSFFNATVLVAVNFLCELEIVNIINYFHT
                     GFLNEVYSSNLKFLMLLARAVLFLVAMVIVYFQKKRKQSEKAEIEGFLATGIVLCILVL
                     YAALTKVLMIIPDIDNGGLMVFIALLISSIVLILTMSLLSLANKRNEELRMAQLAIQKR
                     EGDEVLLKTASEKDEKMRILIHDMKKHFQTLKLMNEYGEVDKVNKYLDNLLEDSDVKSV
                     EDISNNTFLGAILYRYTLKAKEKNIRMNCDIRDKCIEGIDEMTITTILYNLLDNAIENC
                     GGESPFINISIQKKNDSYVNINILNRSIKKPVQNKYGDFISDKPDKTMHGLGLKSIKST
                     IKKNGGEFSAYYSPEDKVFHAVVILYVEK"
     PFAM_domain     complement(8662..8973)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_33_0012"
                     /evalue="6.30E-16"
                     /label="ctg4_33"
                     /locus_tag="ctg4_33"
                     /protein_end="424"
                     /protein_start="320"
                     /score="58.2"
                     /tool="antismash"
                     /translation="DEMTITTILYNLLDNAIENCGGESPFINISIQKKNDSYVNINILN
                     RSIKKPVQNKYGDFISDKPDKTMHGLGLKSIKSTIKKNGGEFSAYYSPEDKVFHAVVIL
                     "
     CDS             complement(10001..10564)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_34"
                     /sec_met_domain="AgrB (E-value: 1.2e-31, bitscore: 101.2,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKKGKITDWLIKSNVIQAEDRDLYDYACRSLVFLFAPFVIALVVG
                     MVFRMVAEALLMAVPYVVLRSFCGGFHLKSIKLCLVVSTLSYLAIFSIGVFVSCDIFYY
                     VTAVISAVSIDALSPIVSPDKKIDSGRIIHFKLTAIILSTIILIVVFVLFIMHIGYFSR
                     FLTLGMLLTASLQWPCIGGSHIID"
     PFAM_domain     complement(10031..10552)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_34_0013"
                     /evalue="6.20E-29"
                     /label="ctg4_34"
                     /locus_tag="ctg4_34"
                     /protein_end="178"
                     /protein_start="4"
                     /score="100.7"
                     /tool="antismash"
                     /translation="KITDWLIKSNVIQAEDRDLYDYACRSLVFLFAPFVIALVVGMVFR
                     MVAEALLMAVPYVVLRSFCGGFHLKSIKLCLVVSTLSYLAIFSIGVFVSCDIFYYVTAV
                     ISAVSIDALSPIVSPDKKIDSGRIIHFKLTAIILSTIILIVVFVLFIMHIGYFSRFLTL
                     GMLLTASLQWP"
     CDS             complement(10806..11513)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 169.6; E-value:
                     1.5e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_35"
                     /transl_table=11
                     /translation="MMKNELEIINLNKQFKDVKALNNINYTFHNGIYGLLGPNGAGKST
                     LINAITDNIKRDSGSILWNGNEILRLGKKYRNELGYMPQQQGYYGEFTAYAFMMYLAGL
                     KGLDKKEAKTRTEELLNEVNMYEFRNKTLEKMSGGMKQRVLLAQSLLNNPSLLVLDEPT
                     AGVDPQERVNIRNYIHSIAKDRIVLISTHIISDIEMIANEIIIMNHGKFLCTLDDEENV
                     EDAYLKWIGDKKI"
     PFAM_domain     complement(11022..11453)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_35_0014"
                     /evalue="6.20E-31"
                     /label="ctg4_35"
                     /locus_tag="ctg4_35"
                     /protein_end="164"
                     /protein_start="20"
                     /score="107.8"
                     /tool="antismash"
                     /translation="LNNINYTFHNGIYGLLGPNGAGKSTLINAITDNIKRDSGSILWNG
                     NEILRLGKKYRNELGYMPQQQGYYGEFTAYAFMMYLAGLKGLDKKEAKTRTEELLNEVN
                     MYEFRNKTLEKMSGGMKQRVLLAQSLLNNPSLLVLDEPTA"
     CDS             complement(11510..13582)
                     /locus_tag="ctg4_36"
                     /transl_table=11
                     /translation="MEFKKVIIYKKIFAGIAFLCILQLLFFAYINRNYVKTVHDENYTL
                     NYSDYVGEVVKKAESMSKVSIFYKADSFSKANIEKTLKDYKKLQDVKIASFDDNFMTAH
                     FQYKELFGFVLIAGILVVFVYKPEKEKGIKGLLYATKNGRGVMAARRLTAILLWDALIV
                     MAFYGANLICSGIILKGNVFTSLTYPIQSIEIFKNWTATDTIGIFLLKYYVYRVFILFA
                     ISAILYMLFTIFNNEIIPLGIAAIIGGIQYGMTRLTNDNTACNILKYCNLYCLASSNTF
                     FTRYKNINVFNKAVGKNVMMAGFVGINIVIASLTGILVSHCKRTYVKGLKINILGKTIG
                     NIRNSVQLKIPETYKIMWIEKGLIILAVLAFVVIRSTYFGVNEKNRAKDMYFAFMDKYE
                     GVPGYDSAKEIDDLRNTLDEVDAQYQRVEEAHSKGLVSDSEYINMQLVMQTYMEDKMFL
                     QEIESQTDYLKENTKNGWYVNKYKYGRLFKNDNTMVNLVTFVTVVLLCSGIFYYERKKG
                     MNGLLRQCINGREKLFNKKMRYAVLTASAVGIFEIILEVSSAIHGYGAIVMKAPVQSLE
                     TFWFVKWNCSIGMFYIFVCLMRIAITVMIAMVAASLSVITSQTISFMFAFILCIPSLLY
                     LIGINFMEKLSIIDVMSVSPYIVRHGSVNAIIYAMVFLTAATASVYHIAYRKWCK"
     CDS             complement(13584..14765)
                     /locus_tag="ctg4_37"
                     /transl_table=11
                     /translation="MKKRTLAAFIAVGLLLCGCSGKNNNDNNTNKDIDNNVDNNINYVV
                     GDYDFSYNEKTDSSVGYEWGYMSESHDGYYVSLQNNLKFLDSKLENCVPLCSNPDCTHN
                     TEECVSYIDRNGISLSSSVYYNDGYVYETGVEKVENTGCDINLYRLKDDGTSFEKYMTL
                     YRLEVNDDETPGYPEICIHRGYVYYVIPFQSTMKLQRMKLGSKEAETVYEMTGDRQNLY
                     RIRAYGNHIFFQAGNFLADNIDINASIFSYDIDTGKVEKVVENAVSYYGIGINRLYYSL
                     DGGVQVYDFEKKTSEEFIGKIYEEQSMLVSDKYVTVYDKSNMQVYDFTGKKVYERNLDK
                     DNISSIYGIDGDTVFVYIYKKGEPGIKGIKGLGYFKIASDDTFVPIEVYETEN"
     CDS             complement(15032..16213)
                     /locus_tag="ctg4_38"
                     /transl_table=11
                     /translation="MKKRTLVVFIAAGLLLCGCSGKNNNDNNTNKDIDNNVDNNINYVV
                     GDYDFSYNEKTDSPVGYEWGDMSESHDGYYVPILGNIKFLDSKLENCVPLCSNPDCTHN
                     TEECVSYFYRNDISLVSQVYYYDGYIYEVGKKTVENKGCDTNLYRLKDDGTSFEKYMTL
                     YRLEAGDGEVTPYPEVCIHRGYVYYVIPFQSTMKLQRMKLGSKEAETVYEMTGDRQNLY
                     RIKAYGNHIFFQAGNFLADNIDINASIFSYDIDTGKVEKVVENAVSYYGIGINRLYYSL
                     DGGVQVYDFEKKASEEFISKIYEDQSMLVSDKYVTVYDKSNMQVYDFTGKKVYERNLDK
                     DDISAIYGIDGDTVFVYINRKGKPEIKGIQGLGYFKISSDDALVQVDIYEIEN"
     CDS             complement(17323..18888)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 99.2; E-value: 5.5e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_39"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.7e-24, bitscore:
                     78.2, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDMSNISEQEIAYVELDASVFVAENYSVDANVITPFAVKQNSDFN
                     IDATLDKAQIEVKYEEYRQIRIDEICDEVADINQSFLQKYNIQAESVSLSLPDINLVYL
                     TAEEIENISKDNSVERIDIVDIYETYSCGYSLSSADSCIRSNTSRNNGYDGTGVKIGVV
                     EHGWANRNLIGSKLTNVGGPTTGTDDHATFVAGEIHTLVPGANIYLIKSASNTTVADLD
                     ALERLMTVNKVQVINMSLGFNSYGQYNDASRRLDRLVRQNKVTVVVAAGNNNTYVSGYG
                     VANNVITVGSVNHRGYTTASSSTYTFSSFSDYAEASGVINKPDVCAPGENLNLYGYTGW
                     SGTSMATPLITGIVAQMIDRNSGMSDKPQILKAAVMASCYFNARTGFTNNISNKEGAGV
                     VDANFTYRVAQNGRRWHFDFTPSSASSQTHSIYADYTSKAFRISIAWEGEIVNNTNKVT
                     DYDLYIYKGNTLVASSTGVRNNEVIIIPASKIAQYGAGYYTAKIVRYGTAKTSSDRVGL
                     AWEQ"
     PFAM_domain     complement(17695..18333)
                     /aSDomain="Peptidase_S8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00082.24"
                     /description="Subtilase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_39_0015"
                     /evalue="2.50E-25"
                     /label="ctg4_39"
                     /locus_tag="ctg4_39"
                     /protein_end="398"
                     /protein_start="185"
                     /score="89.4"
                     /tool="antismash"
                     /translation="GTDDHATFVAGEIHTLVPGANIYLIKSASNTTVADLDALERLMTV
                     NKVQVINMSLGFNSYGQYNDASRRLDRLVRQNKVTVVVAAGNNNTYVSGYGVANNVITV
                     GSVNHRGYTTASSSTYTFSSFSDYAEASGVINKPDVCAPGENLNLYGYTGWSGTSMATP
                     LITGIVAQMIDRNSGMSDKPQILKAAVMASCYFNARTGFTNNISNKEGAG"
     CDS             complement(18910..19113)
                     /locus_tag="ctg4_40"
                     /transl_table=11
                     /translation="MKRIRFISTILALSIAIVPFTLGASAQALPISNADTISSRLMSVM
                     EQKSSDSSAKIPVQIQLKDTVD"
     CDS             complement(19129..19770)
                     /locus_tag="ctg4_41"
                     /transl_table=11
                     /translation="MKRFLILVGGFALSCCFVFSGCSNHSANTSDVDVAKGMGISSPDD
                     IISSPVDPVKSAEEQPTIQPDFPKEEADKKEVADNKSAIANDVRSEQASDTPATSNSLV
                     ISAFRSLWKEKGDQTSVSLSEQNVKLLGTISTKFELYEIIPENASGDSIMTYQTYQGYT
                     IVSGTRYQPSAFALYLFDKDKNVLYTIEDGAQLVDFSAVYNLLPNNMKKQ"
     CDS             complement(19844..19945)
                     /locus_tag="ctg4_42"
                     /transl_table=11
                     /translation="MVFVYNYSCFGEGRFTSYDLLLNSVRFHLIFNR"
ORIGIN
        1 atgggtatca tctattctct ctgtccatgc tctcatcgcc tccgatacag catccttaag
       61 tgttgccgta cctgttttga ctgcatggac ttttgctccg aggagtctca ttctatatac
      121 attaagtgcc tgtcttattg tatcttcttc tcccatatag atttcacatt ccataccgaa
      181 aagtgctgct gccgttgctg ttgcaacacc gtgctggcct gctccggttt ccgctattac
      241 tcttgtttta cccatttttt ttgctaataa cacctgtccg agaacgttgt ttaacttatg
      301 tgatcctgta tggttcagat cctctctttt aagataaatc ttagcgcccc caaggtcttt
      361 tgtcatcctg tcggcatagt aaagaatgga tggtctgcct gcgtaatttt ttaaaagtcc
      421 gtcaagctcc ttattaaatt cttcatcatt tttataatgt tcgtatgctt cttccaattc
      481 attaattgca ttcatcagtg tttcgggtat gtactgtcca ccgtgaatac caaatcttcc
      541 ttttgacatt ttataattcc tttctgcatt tatttattat ttttcttatt ttatcttcat
      601 ctttgaagcc atcggtttcg actccgcctg atacatcaac agcgtaaggt gatatggcaa
      661 ttgcttcatc aatattggat tcgttaattc ctcctgcaag gaaaaacggt tttgtcacat
      721 ttcctataag cttccagtca aaacattttc ctgtccctcc ttttccgtta tccaaaagaa
      781 tatagtcggc accgctttcg ttatattttt cacaatctga ttgtgtttct acggaaacag
      841 ctttaattac aggtctgccc gtcatcttct ttatgaacag gatatcctcc tccggttcag
      901 ttccgtgaag ctgtgcaata tctattacgc cgtcattgag gtattcagcc acaatttcag
      961 gcttttcatt tacaaacacc ccaacggttt ttatttccgg cagaagtctt ttccttaatt
     1021 ccattgcatc ggcttcagat atgtatcttt tggatttttt ataaaatata aaccctatat
     1081 aatcggggcg gtatttattg acgatttcaa tatctgctgc tcttcttata ccgcatattt
     1141 ttattttctg cattgtcaga tacctcttaa tgctgctatt gtatttttct tatccgcgga
     1201 acgcataagg gtttctccta tcaatacggc atcagttccg ttttcgtata atcttttaat
     1261 atcctccgca ttttttattc cgctttccga tacataaaga taatccttgg gtaccatatt
     1321 cctgagtctt aagcttgtgt tgatatccac ttcaaaagtc tttaaatttc tattattaac
     1381 cccgattatt ctgccgtatc tgagagctgt ttcaacttct ttttccgtat gggcctcaat
     1441 aagcaccgac aatccgagtt ctcctgcaag ttctgaatat tctttaatct cagcctccgt
     1501 aagtatggcg catattaaaa gaattgcaga agcacccatt attttagctt catataccat
     1561 atatctgtca acggtaaaat ctttacggag cacggggatt tttacttctt ttgcaatttc
     1621 tttaagataa tcgttgcttc ctttaaaata aaagggttct gtaagacatg agattgcgtc
     1681 tgccccggca ttttcgtact cttttgctat ttccagatac ggaaaattct ctgctatcac
     1741 gccttttgac ggcgaggctt tttttacttc acatataaaa gacagtcctt ttttggaaag
     1801 tgctttttca aaagggaaat cattgtttat ttccattgaa aaagcttttt tttcaagctc
     1861 ttccatggtc gtaatttctt ttaactttgc tattctttcc tttgtctttc ctgctatttc
     1921 gtcgagaatc attctatgcc tccccgttgc ttaatttgac aaactgttca agttttctca
     1981 ttgccgcacc gttatctatt aattcttccg ccagtcttat accggatttg attgactctg
     2041 cttttcctgc aacatacaaa gcagctcccg cattaatgac aacagcggtt cttcttccac
     2101 ttttttctcc attaaggaca gctttgctta tttcggcatt ctcttctcct gttcctccgg
     2161 taagttcttc tttggtacaa cgtgtaagcg aaaactgttc cggcgtaatt tcataacttt
     2221 taaattctcc atccataact tcacatacct ttgtaggtgc ggatgctgaa atctcgtcca
     2281 tgccgtcttc accgtacaca accatagctc tttttacacc aagattgtaa aggacatgtg
     2341 caagactttc tacaaacttt tcggaaaaaa cacccataag ctgcattgac gcattggcag
     2401 gattcgtcag cggtccgagg atattaaaca ccgttctgaa cccaagtttt tttctgattg
     2461 gtgcaacata tttcattgcc gaatgatact tctgtgcatg taagaaacag atatccgctt
     2521 catcaaggca tttcttacta actttttcat ctgcaagaat attgacgcca agtgcctcaa
     2581 ggcaatccgc agcaccggat ttgcttgaag ctgccctgtt gccgtgtttg gttaccggta
     2641 ctcctgccgc agcaattata aaagatgctg ttgtagaaat attgaaagag ttggaaccgt
     2701 ctccgcctgt gcctacaatt tcaaaggttt ctttgtctgt taaaaggtgt gttcctgctg
     2761 ctctcattcc cttggccgat gcggttatct cttcaacagt ctcccctttc attgtaagtg
     2821 ccgtaaggta agagcttatt aatacgggat ctgtttcccc cgacataatt tcatccatta
     2881 ctttttttgc catatcttct gtaagatttt ctttatttat aagtttgatt attgcttcat
     2941 ttatcataat tcttatctcc tgctgttaat aaaattttcc atcattcttt taccatcttt
     3001 tgtaagaatg gattccggat ggaattgcaa gccgtatacc ggatactctt tatgctctac
     3061 cgccattatc tctccgtcat ccgtttctgc cgttatctta aggcagtcag gcagggtttc
     3121 tttaacggcc gctaaagaat gatatcttgc aacagatatt ttattatcaa atcctttaaa
     3181 aatcaccgaa tccgtatctg catttataac ggaagtctta ccgtgcataa gttcttttgc
     3241 ataagatacc gttgcaccga aggctttgca tattgcctga tgtccgaggc atacgccaag
     3301 aattggtatt ctgcctgcaa aatatttaat aatatctata catattccgg cattttcagg
     3361 tcttcccggc cccggcgata taattattaa atcaggattt aataatttaa tttcttttac
     3421 agtcatttca tcatttctta taacctttat atcaggttct atctcacctg taagctggta
     3481 taaattatag gaaaagctgt cataattatc tacaagtaat atcattgtca attcctccct
     3541 ctgcttcttt taaagcattc attacagcct tagctttatt aatgcattct tcaaattcat
     3601 tttcgggaac cgaatcggca acaattcctg ctcccgacct tacaaacact tttccgtttt
     3661 tggcaaatgc cagtcttatc gcaatacatg tatcaagatt tcctgtgaaa tctatgtaac
     3721 ctatggcacc gccataaatt cctcttttat tattttcaag ctcacatata agctcgcagg
     3781 ccttaagttt cggtgccccg gaaagcgttc ccgcaggcag tattgaatcc actgcattta
     3841 aagcatccat atcgtctctt atgatacctc ttaccgttga accgatgtgc attacatggg
     3901 agtatctttg tatctccata tatctttcaa cttcaacaga accgattctg cttattctgc
     3961 ctatatcgtt tcttcccaga tcaacaagca tattgtgttc ggcaagttct ttttcgtcct
     4021 gcagaagttc tttttcaagt cttaaatctt cttctgtatc cgcccctctt tttcttgttc
     4081 ctgcaagagg aaaagtatga agctctccgt tttcaagttt tacaagggtc tccggtgacg
     4141 cacctgcgat ttccacatca tcacttgaaa aataaaacat ataaggcgat gggttggttg
     4201 ttcttagtac cctgtaagtg tcaaaaagac ttccttcaat atctgcctca accctgtttg
     4261 aaaggacaat ctggaatatg tcaccttcaa aaatatgtct tttgcccttc ttgaccattt
     4321 cacaatactg ttctttgtca aaaagatacc tgaaatcact tttaagctgc aatggtctgt
     4381 tttcttccat ttcaccctca agcagcagtt tcttcatatt ttcaagttcc attacccctt
     4441 tattataaga ggtgtcaaaa ttctctgttc tgacattcac aatcagtatt attttctgtc
     4501 tgtaattatc aaaacatatt attttgtcaa aaagcataag gtcaacgtcc ttaaaggatt
     4561 cctcgtcctt agcgcttaac tttaacgaag gctcactgta ttttatataa tcgtaagaaa
     4621 aatatcctac cagtccgcct gcaaaaggtg gaaggccttc aagtacaggt gttttattgt
     4681 ctttgatgat ttttcttata tattccatgg gatgggtcac tttttcgata atctcaaatc
     4741 cgctttttat ttttaaaact ccatcctggc aggtaagttc aagtgtaggg tcgaatccca
     4801 aaaaagtata tcttccccac ttcttatctg cctcagcgct ttctaacata aaacagtgat
     4861 ggcttacttt cttaagtctt ttcactgcca taacaggtgt taccatatcg gaattaagtt
     4921 ccatggttac aggaattctc ttataatcgc ctgttgcaat aattttctta gcttcctccg
     4981 gtgtcggata catattttcc tctctttcct gtcaggaagc aataaaaaag cccctgacaa
     5041 tatcattaat attgtcaagg gcgaatattc aatccgcggt gccaccttga ttcacataaa
     5101 atgtgctctc ttcgagatac caacatatcc caggcaacta acgtatgccc tacgtcatag
     5161 aatactaagc ccttagctgt tcactatgcc ctcagtggtc catttgataa tctgcgttca
     5221 acccagctct caccatccca ggctctctgt gtgtgcaaca actaacgtta tctccacttc
     5281 aacggtttaa agtgttcaat ttatttctta taaattacca tagggcacct gtattgtcaa
     5341 tgatattttt taagattatt atcaatttcc actgccctgt gtctccacag atggccgctg
     5401 catacaagca tatgcccctg ttttgcaatg tcgtccctat gtactgcact gtttactatg
     5461 tcaggaatct cctgcatatt atcaagactg aatcttagat attctacacc atcttttgct
     5521 atctcatcta tatagaggga actgtcagat accacaactg agccctgtgc catgccatta
     5581 aaaaatctgt catggacacc gtctttaaac caaggcataa tatttaccga tactttgctt
     5641 cttttcatat atctgaggca ttccaaagaa tccctttgtc ctatcagaac cagattttca
     5701 ggtttcttac atccggcttt ttcccagtct ttcccgataa tatgtacctt aattccattt
     5761 tccgcaagat tacatataat cttttgcctg aaatatgacc ttatatacaa gtcaattacc
     5821 atcatcttat tagtaaccat aagcatatct tctcttgtaa tatcaggtat atcagctctt
     5881 acatgctcct caattacttc atctattcct ttgcctgtat tggtctttaa atcctcaatc
     5941 attgaataac aaaattccct gttgtcctta tccagcatat ttattctgtc ttcaagcggt
     6001 ttgatattca cataatttcc cgcaaaaaat acatcaatat cccttttttg cccaccttcg
     6061 tcaagggaag ttcccgcaag aggtaaaaaa tcaaccttct taccgggata atatcttctt
     6121 ataaaatcca catgctgcct gtcaatacaa tacagcatac aatcattaat catttccagc
     6181 tggtccctgt aataaagagg atggtcaacc atgatgcaga cttttttaat accataataa
     6241 tcccagacag aagtctcttt accatctgtt ccctcagcca taaactggct ttccccgctt
     6301 agtccgataa aattaaaagt tataagtaca gccttttctc ttatgttttc aataaagtgc
     6361 ctgctctcaa gaggtttttt catatcccat gcaattacgt ttttatttaa ttccgtataa
     6421 aatgtctccg ccagcctctc cgaaaaaaaa gacagtgttt ccaccggacc ttttataatt
     6481 ataacgtcag tataatccat aatatgccct ccgtttacat ttacaaaaaa agtaccggga
     6541 aatcccattt ccggtactct taaaaatgcg gataacagga gttgaacctg cacgggtgtt
     6601 cccactagaa cctaaatcta gcgcgtctgc caattccgcc atatccgccc gcagcattta
     6661 ttgactgctc ctatgattat atcctttttt attattttat tcaactgttt tatcagcagc
     6721 ttcatatatt gcctgcgcaa gacttgaaag tgccgcttta tcgctttcct taaccgtgga
     6781 cttaatcgtt acaacaggtt caaccactgt aatatttttg aaggtatcaa caatgtttct
     6841 catcactctt gccgcacatg gtgcccagga accgttctca accattccca cagttctgtt
     6901 ctgataagcc tttgactgca ggcgtaaaag gaaatcctgc atgcaaggga acacccctcc
     6961 gtcataactt gcggcacaaa gaatcattct gtcatatctg aaagcatctt caattacctc
     7021 tgccatatct tctcttgata aatcacttac tacaacctta tcttcacctg cttttttaag
     7081 catatcggca agttcatgtg cagccttagc cgtattacca tgaatggacg cataagctat
     7141 caatacgcct ttattttcag gttcatatct gctccatgta tcataaagtc ctatgtaata
     7201 tccaagatta tctttaagta caggtccgtg aagcgggcat atcatattga catcaagtcc
     7261 tgctgctttt tttaagagct gctgtacagg tccgccgtat ttgcctacta tgttaaaata
     7321 atatcttctt gcttcacaag cccagtcttt atccttggta agctctatcg ctccgaattt
     7381 gccgaaacca tcagccgaaa atagaatttt ctcggttgct tcgtatgtga ccattacctc
     7441 aggccagtga accatcggtg ccatgtaaaa gactaattta tgtgttccca gtgaaagttc
     7501 ttctccttct tttacgacaa tgcttctttc tgaaaaatcc atgtcaaaaa actggggaag
     7561 catctgaaat gtcttggcat tgcctacaag cttcatatcc ggatatctga ctgcaagtct
     7621 ttcaatattg gacgaatgat caggttccag atgtgatatc acaagatagt ccggatgtct
     7681 gtcttcaaaa acttctgtaa gattactaaa ccactcatcc gtctttcttt catcaacagt
     7741 atccataact gcaattttat catctaaaat tacgtaggaa ttatatgaaa caccatcagg
     7801 taccagatac tggctctcaa acaaatctat gtcagtatca tcaacgccta tatatttaac
     7861 actatccgaa actatcattt tatctacctc gtttctaaaa atattttact atagtaacat
     7921 catatggatt tttccacata atttataaat gcctctttaa tacttgtata tctgtttctt
     7981 gataaatatg ctacatattt atcgccgcaa agatacactg tgtttttgtc aatccttgat
     8041 acatacttaa gattgattat gaaactccga tggcacatta caaacataag cggattcagt
     8101 cctatcagaa aatcattaat tgttcccata acccttatta cttcgccatt cttcatatat
     8161 agtttcagtc ttcttgaatc tttctcaacc ataacgatat tatatgtatt aactttgcgg
     8221 tacacacaat tcccctcatc aatcacaaca ttaattcttc tcttacacag aatattaaat
     8281 gcatcacata tacattttac aatacgttcc tgattcaatg gtttagatat atatctgaat
     8341 acacaaaagc tcatcgcatc atccagaaat tcagtatgtg acgttacata tgctataagc
     8401 acatcggaat catcctgctt taatgctctg ccgacactaa tcccatcagc ccccggcatc
     8461 tctatatcca gaaaaacaag atccttttcg ccttcatctt ctaacaaatc ttttccgttg
     8521 tcatattcgt cacattccag cagtccctga taaccgcttt ttctcatact tttgaaagcc
     8581 agtctgatat tatcatgtaa tctctgtctt atgtattcgt catcatcaca tattattact
     8641 ctcatattat ttctccacat acaatattac aactgcatga aagaccttat cttcaggact
     8701 ataataagct gaaaattctc cgccgttttt cttaatcgta ctcttaatgc tcttaagccc
     8761 aagaccatgc attgttttat ccggtttgtc tgaaataaag tccccatatt tattctggac
     8821 aggtttcttt atgcttctgt tcaatatatt tatattaaca taactgtcat tttttttctg
     8881 aatagatata tttataaaag gagactcgcc tccacaattc tctattgcgt tatcaagcag
     8941 gttatatagt atcgtagtaa tggtcatttc atcaatgcct tcaatacact tatcccttat
     9001 atcgcagttc attcttatat tcttttcttt ggcctttaat gtatatctgt aaagaatcgc
     9061 acccagaaaa gtattgttgg aaatatcctc tacggacttc acatccgaat cttccaacag
     9121 gttatccaga tatttattaa ccttgtccac ttcaccgtat tcattcataa gcttaagcgt
     9181 ctgaaaatgt tttttcatat catggatgag aattctcatc ttctcgtcct tttccgaagc
     9241 agtttttaaa agcacttcat cgccttcacg tttctgaatt gcaagctgtg ccattctgag
     9301 ttcttcattc ctcttatttg ccaatgagag caatgacata gtaagaatca acactatcga
     9361 agaaatcaac agtgcaataa ataccatcaa gcctccatta tcaatatcag gaattatcat
     9421 caaaaccttg gtaagagccg catataatac caatatgcat aacacaattc cggtcgcaag
     9481 aaatccttct atttcggctt tttcagactg tttcctcttt ttctggaaat atacaattac
     9541 cattgcaacc aaaaaaagaa cagctcttgc cagtagcatt aaaaatttca gattactgct
     9601 atacacttcg ttcaaaaagc ctgtatgaaa gtaattaatt atattaacaa tttccagttc
     9661 acacaagaaa ttaacggcaa caagtactgt agcgttaaaa aaagagtctg ccggatcacc
     9721 ggaatatgca aaccctaata caagtacccc tgccataaca tccgcaaatg cgttaagcat
     9781 ggaattatcc gaatgggtaa gtgcggcaca cccgtataat acaatatata tcaatatacg
     9841 aatcggaagc ttaaaccttg gtatatacat acaccttgca aatataaccg ttacaaaagc
     9901 ctccaggaaa tatgacatta taattacgtc cattattact ttatccttaa tcgttaatta
     9961 tcccaaaaat tactaaataa ttatacattt ttttagtaaa tcagtcaata atatgtgagc
    10021 ctcctataca cggccattgt aacgatgcag taagtaacat tcccaacgta agaaaccttg
    10081 aaaaataccc tatatgcatg ataaaaagta caaataccac aattaaaata atcgtggaca
    10141 aaataattgc tgttaattta aaatgtataa ttctgccgga gtctatcttc ttatcaggag
    10201 atacaattgg actcaacgca tcaatggata cagcgcttat aactgctgta acataataaa
    10261 atatatcgca tgatacaaaa acgccgattg agaatattgc aagatatgac aatgtagaaa
    10321 ccacaagaca caatttaata cttttcaagt gaaatcctcc gcagaaactg cggaggacta
    10381 catagggaac tgccataagt aaagcctctg ccaccatcct gaacaccatt cccacaacaa
    10441 gtgcaattac aaacggtgca aacagaaaga caaggcttct acaggcataa tcgtacaaat
    10501 ctctgtcttc tgcctgtatt acattactct ttataagcca atcagtgatt ttcccttttt
    10561 tcacgttcta caactctttc gtacaaatta tcaggtgtct tttcctgata tgtaataggt
    10621 gatgaaacag tcaccacctc gttcctgagg acaacgtcaa gaagtttctt aactacattt
    10681 gctgttttag ttttcatata aactaccacc ctttctaact tttgtaatac acattgtaat
    10741 ttatttttct tctaatgaaa aggaaaaatt cgctacagat tgtgcaaaaa ttgtattttt
    10801 gtggattata tctttttgtc tccaatccat ttaagatatg catcttcaac attttcttca
    10861 tcatcaaggg tacaaaggaa ctttccgtgg ttcataataa taatttcatt ggctatcatt
    10921 tctatatctg aaataatatg tgtggatatt aggacaattc tgtcttttgc aatactatgg
    10981 atataatttc ttatattaac tctttcctgc ggatcaaccc ctgctgtcgg ttcgtcaaga
    11041 actaacagac ttggattgtt aagaagtgat tgtgccagta aaactctctg tttcattcct
    11101 cctgacatct tttccaatgt tttattgcgg aattcataca tatttacttc attaagaagt
    11161 tcttccgttc tggtttttgc ctctttttta tcaagtcctt ttaatccggc aagatacatc
    11221 ataaaagcat aggccgtaaa ttcaccataa taaccctgct gctgtggcat ataccccagt
    11281 tcatttctgt atttctttcc cagtctgaga atttcatttc cattccagag aatacttccg
    11341 gaatctctct ttatgttatc tgtaattgca ttaattaacg tgcttttacc ggcaccgtta
    11401 ggtcctaaca aaccatatat tccattatga aaagtataat ttatattgtt taacgcctta
    11461 acgtccttga actgtttatt taagttgata atttctaatt catttttcat catttacacc
    11521 atttcctata agcaatatga tacaccgaag ctgttgcagc cgttaaaaat accatagcat
    11581 atattattgc atttacactg ccatgtctga caatatacgg agagaccgac attacatcaa
    11641 ttattgataa tttttccata aaattaatcc cgataaggta caataatgat ggtatacaaa
    11701 gaataaaggc aaacataaac gaaattgtct ggcttgtaat aactgacagc gaagcagcta
    11761 ccattgcaat catcacagtt attgctattc tcataaggca cacgaatatg taaaacatac
    11821 caatactgca attccatttt acaaaccaga acgtctcaag actctgtaca ggagctttca
    11881 taacaatcgc tccatatccg tgtatagcag aacttacttc aagtattatt tcaaaaattc
    11941 ctacggctga cgccgtcaga acggcatatc tcatcttttt gttaaaaagc ttctctctac
    12001 cgttaatgca ctgcctcagg agtccattca tgcctttttt gcgctcatag taaaagatac
    12061 cgctgcataa caatacaaca gtcacaaacg taacaaggtt taccatggta ttatcatttt
    12121 taaacagtct gccatatttg tatttattga cataccatcc attttttgta ttttccttaa
    12181 gataatctgt ctgactttct atttcctgca aaaacatttt atcttccata tatgtctgca
    12241 taacaagctg catatttata tattccgaat cactgacaag gcctttacta tgggcttctt
    12301 caactctttg atactgtgca tccacttcgt caagtgtatt ccttaaatca tcgatttctt
    12361 ttgccgaatc atatcccgga acaccttcat acttgtccat aaatgcaaaa tacatatcct
    12421 ttgccctgtt tttttcattg actccaaaat atgtgcttct tataacaaca aaagcaagca
    12481 cagccagtat gattaatcct ttttctatcc acattatttt atatgtttca ggaattttta
    12541 actggaccga atttcttata ttacctattg tcttaccaag gatatttatt tttaaacctt
    12601 taacgtaagt tcttttgcaa tggcttacca gtatgcccgt taatgaggct ataacaatgt
    12661 taatgcccac aaatcctgcc atcattacat ttttaccgac agccttatta aacacattaa
    12721 tatttttgta cctggtaaaa aatgtattgc tcgatgcgag acagtacaaa ttacaatatt
    12781 tcaaaatatt acatgccgta ttatcattag tgagtctcgt cattccatac tggattccac
    12841 ctataatggc agcaattccc agaggaataa tttcattatt aaaaatagta aacagcatat
    12901 acaatattgc agatattgca aatagaataa atactctata tacataatat ttcagcaaaa
    12961 agattcctat cgtatctgtt gccgtccagt ttttaaatat ttctattgat tgtataggat
    13021 atgtaaggct tgtaaacaca ttacctttta atattattcc gctgcatata agattagccc
    13081 cataaaacgc catgacaatt aaagcatccc ataagagaat agctgtcagg cgtctggctg
    13141 ccatcacgcc ccgcccattt tttgtcgcat ataagagtcc ttttataccc ttttcctttt
    13201 cgggtttgta tacaaatacc accaaaattc ctgcaataag tacaaatcca aaaagttcct
    13261 tatattggaa atgagcggtc ataaaattgt catcaaagga agcaatcttt acatcctgca
    13321 gtttcttata gtctttcaaa gtcttttcaa tattcgcctt tgaaaacgaa tccgctttat
    13381 aaaatatgct tactttggac atactttctg ctttttttac cacttctcca acataatccg
    13441 aataattcag ggtataattt tcatcatgta cagttttgac gtaattccta ttgatatatg
    13501 caaaaaacag caactgtaaa atacataaaa aggctattcc tgcaaatatt tttttataaa
    13561 taattacctt cttaaattcc atatcaattc tctgtctcgt aaacttctat cggtacaaac
    13621 gtgtcatcag aagctatctt aaaatatcct agtcctttta ttcctttaat tcccggttct
    13681 cccttcttgt aaatatatac aaaaacagta tctccgtcta ttccatatat actgctgata
    13741 ttatctttat ccagatttct ttcatacacc tttttgcccg taaaatcata tacctgcata
    13801 ttacttttat catataccgt tacatattta tcggatacaa gcatactctg ttcttcgtaa
    13861 atcttaccaa taaactcttc agatgttttc ttctcaaaat catacacctg tacaccgcca
    13921 tccagactgt aatatagcct gttaatgcct atcccatagt aggaaaccgc attttccact
    13981 actttttcaa ccttaccggt atcaatgtca tacgaaaaaa tgctggcatt tatatcaata
    14041 ttatctgcca agaaattacc tgcctgaaag aaaatatgat ttccataggc tcttattctg
    14101 tacagattct gtctgtctcc tgtcatctca tacacagtct ctgcttcctt acttcccagt
    14161 ttcattctct gaagtttcat tgtactttgg aatggaatca cataatacac atatcctctg
    14221 tgtatgcata tctcaggata tcccggagtt tcatcatcat ttacctccag cctgtataat
    14281 gtcatatact tttcaaaaga tgttccatca tctttcaatc tgtataagtt aatgtcacat
    14341 ccggtatttt caactttttc tacaccggtc tcatatacat atccatcatt ataataaaca
    14401 gatgaagata atgatatacc gtttctgtca atatacgata cacattcctc agtattgtgt
    14461 gtacaatcgg gattactgca aagcggtaca caattttcaa gcttactatc taaaaattta
    14521 aggttatttt gtagcgaaac atagtaaccg tcatgtgatt cactcatata tccccattca
    14581 tatccaacgg atgaatcagt cttttcgtta tagctaaagt catagtctcc cacaacataa
    14641 tttatattat tgtcaacatt attatctata tctttgtttg tattattgtc attgttgttt
    14701 ttcccactac atccacataa taataaccct acagcaataa atgctgccaa tgttcttttt
    14761 ttcatgataa attacctcca tttaaattta attttatact tgaccggtcg cttgtattct
    14821 aacataatta ttaatgcaca aaaaccctct ttgcataaac ggtgcgattt cgtgcataaa
    14881 cggtattact attagtgaat agtaaatgat atgtcataga attctctacc ttttcggctg
    14941 atttccgcta ttttggtaga gatttacgga cggcaacaat ggcaattcct gcaaatattt
    15001 tttataacta attgccttct taaattccat atcaattctc tatctcgtaa atatctacct
    15061 gtacaagtgc atcatcagaa gatatcttaa aatatcccaa tccctgtatt cctttgattt
    15121 caggttttcc ttttctgtta atatatacaa agaccgtatc tccgtctatt ccatatatcg
    15181 cactgatatc atctttatcc agatttcttt catacacctt tttgcccgta aaatcatata
    15241 cctgcatatt acttttatca tataccgtta catatttatc ggatacaagc atactctggt
    15301 cttcgtaaat cttactaata aattcttcag atgctttctt ctcaaaatca tacacctgta
    15361 caccgccatc cagactgtaa tatagcctgt taatgcctat cccatagtag gaaaccgcat
    15421 tttccactac tttttcaacc ttaccggtat caatgtcata cgaaaaaatg ctggcattta
    15481 tatcaatatt atctgccaag aaattgcctg cctgaaagaa aatatgattc ccataggctt
    15541 ttattctgta cagattctgt ctgtctcctg tcatctcata cacagtctct gcttccttac
    15601 ttcccagttt cattctctga agtttcattg tactttggaa tggaatcaca taatacacat
    15661 atcctctgtg tatgcacact tccggatatg gtgtaacttc accgtcgcct gcctccagtc
    15721 tgtacaatgt catatacttt tcaaatgatg ttccgtcatc tttcaatctg tataaattag
    15781 tgtcacatcc tttattttca actgttttct ttcctacctc atatatatat ccatcgtaat
    15841 aataaacttg tgaaactaat gatatatcat tcctataaaa atacgataca cattcttcag
    15901 tattatgggt acaatcggga ttactgcaaa gcggaacaca attttcaagc ttactatcca
    15961 aaaatttaat gttccctagt atcggaacat agtaaccgtc atgtgattca ctcatatctc
    16021 cccattcata tccaaccggt gaatcagtct tttcgttata gctaaagtca tagtctccca
    16081 caacataatt tatattattg tcaacattat tatctatatc tttgtttgta ttattgtcat
    16141 tgttgttttt cccactacat ccacataata ataaccctgc agcaataaat actaccagtg
    16201 ttcttttttt catataaatt acctccattt aaatttaatt ttttatttga ccggtcactc
    16261 gtattctaac ataattatta atgcacaaaa accccctttg cataaacggt acgatttcgt
    16321 gcataaacgg tattactatt agtgaattgt aaatgatata tcataggatt ctctaccttt
    16381 tccgccgttt ttttgctgtt tgggtagaga tttccgattt ttgcataaga aatttactac
    16441 aaagtaaaat aaaaaaggac tgcatcgtaa tgcaatcctc taacttagtg agccatcggg
    16501 gactcgaacc ccggacaact tgattaaaag tcaagtgctc taccacctga gctaatggcc
    16561 catattaaat tattgttgac cttaactggg ctagttggat tcgaaccaac gtatgcagca
    16621 gtcaaagtgc tgtgccttac cgcttggcga tagcccaatg gattaaaaag ggtggataaa
    16681 gggattcgaa cccttgacct ccagagccac aatctggcgc gctaaccaac tgcgctatac
    16741 ccaccataat gtaaacgccc attgtatcag cgtactcgca aagcgaatgt gcccgaaggg
    16801 attcgaaccc ccgacccacg gcttagaagg ccgttgctct atccagctga gctacggaca
    16861 cacatcatat tcacataaaa gcgaatatta agcgggtgat gggaatcgaa cccacgtatc
    16921 tagcttggaa ggctagtgtt ctaccattga actacacccg caaagtcggg gtgacaggat
    16981 tcgaacctgc gacctcttga tcccaaatca agcgctctag ccaagctgag ccacaccccg
    17041 gtattctgtt gtgtttgtcg tctctgtcag acgcaagtgt tattataggg tataagtccc
    17101 ataatgtcaa cacttttttt aaaaaaattt taaaaatttt taaagagcct gaaagcccgc
    17161 ttaaatactg tctttcacaa ggacactttt gaaaaacaac cgattgagag acacgcagcc
    17221 cgctgacaat aaatcagcgg gctgtgtgct ttgttattgg cttcacttaa agtaacacaa
    17281 agctacggta gaggtattat tgctgattat gaaaaatcaa ctttactgct cccaagccag
    17341 tccaacacgg tcagacgatg ttttagccgt gccatatcta acgatttttg cagtataata
    17401 tcctgcgcca tattgagcaa ttttcgaggc cggaataata atcacttcat tgttccggac
    17461 tccagtgctg gacgccacta aagtatttcc cttgtaaata tagagatcat aatctgttac
    17521 tttgttggtg ttgttaacta tctcaccttc ccatgcaata ctaattcgaa atgctttgct
    17581 ggtataatcc gcatagattg aatgcgtttg tgaagatgca ctacttgggg taaaatcgaa
    17641 atgccatctg cgtccatttt gagccactct gtatgtaaaa ttagcatcta caacgccggc
    17701 accttcctta tttgaaatgt tatttgtgaa accagttctt gcattaaagt aacaacttgc
    17761 catgaccgca gctttgagta tttgtggttt atcactcatt ccagaattac gatctatcat
    17821 ttgtgcaaca atgcccgtga taagtggtgt tgccatgctt gttccactcc aaccggtgta
    17881 accgtataaa ttcagatttt cacctggggc acaaacatca ggcttattaa tcactccaga
    17941 agcttctgca taatccgaaa aagatgagaa ggtatatgtg gacgaggacg cagtagtata
    18001 tccacggtga tttactgagc caacagtaat aacattattt gcaactccat acccactaac
    18061 ataagtgttg ttattaccag cggcaacgac aacggtcact ttgttctgtc ttactaatcg
    18121 atccagtctg cgagaggcat cgttatactg tccatagctg ttaaagccga gtgacatatt
    18181 gatgacttga accttattta ccgtcataag ccgttccaat gcgtccaaat cagcaacagt
    18241 agtgttcgaa gctgacttaa tcaagtagat atttgctccc ggaactaatg tgtgaatttc
    18301 tccggcaaca aatgtcgcat gatcatctgt gcctgttgtt ggacctccaa catttgtgag
    18361 tttagagcca atcagatttc gatttgccca accatgttcc acaacaccaa ttttgacacc
    18421 tgtaccatca taaccattgt ttctactggt gttagaacga atacaagaat ctgcagaaga
    18481 aagactatat ccgcatgaat atgtttcgta aatatcgaca atatcaattc tttcaaccga
    18541 attgtctttt gaaatatttt cgatttcttc tgctgttaag tagacgagat taatgtcagg
    18601 taaagaaagg gagacacttt cagcttggat attatatttt tgcaaaaatg actggttaat
    18661 atccgccacc tcatcgcata tttcatcaat tctaatctga cgatactctt catacttaac
    18721 ttctatttgt gccttgtcaa gagtggcgtc tatattaaaa tcggaatttt gctttactgc
    18781 gaaaggtgtg atcacatttg catcaacaga ataattttct gcaacaaata cacttgcatc
    18841 caattcgaca taagcaattt cctgctcaga aatattggac atatccatag cttgtttctc
    18901 aacagatacc taatcgacag tatcctttag ctgtatctga acaggtattt tcgcagaaga
    18961 atcagaactt ttctgttcca taacactcat caaccggctg gagattgtgt cagcattgct
    19021 gatgggcaat gcttgtgcag atgcacccaa tgtgaacgga acaatagcaa ttgagagagc
    19081 gagaatagtg ctaataaatc ggattcgttt cataccttac actccttttc attgtttttt
    19141 catgttgttt ggcaacaaat tgtagacagc cgagaaatca acaagctgtg cgccgtcttc
    19201 tatggtgtac aaaacattct tatctttatc aaaaagatat aaagcaaatg ctgaaggctg
    19261 atagcgtgta ccggacacaa tcgtatatcc ttgatatgtc tgataagtca taattgaatc
    19321 gccgcttgca ttttccggaa tgatttcata caattcgaat tttgtactaa tcgtacccag
    19381 caatttcaca ttttgttcgg acagagatac agaagtctga tctcctttct ctttccatag
    19441 tgaacgaaat gctgagatga caagactatt ggatgtcgcc ggagtatctg atgcttgctc
    19501 agaacgcaca tcatttgcaa ttgctgattt attatctgcc acttcttttt tgtctgcctc
    19561 ctctttgggg aaatccggtt gtatggttgg ctgttcttca gccgatttca caggatcaac
    19621 aggtgaagaa ataatatcgt ccggcgacga aatccccatg ccttttgcca catccacatc
    19681 cgaagtgttt gcagaatgat tagaacaacc ggagaaaaca aaacagcaac tcaatgcaaa
    19741 acccccaacc aaaatcaaga atcgtttcat ataaatacct cctttattga gcgctcaaaa
    19801 aaaacaaaag tgcataaacc gattgtcgtt cggcttatgc gctctatctg ttaaaaatca
    19861 aatgaaacct tacgctattt aatagaagat catatgatgt aaaccgccct tcaccgaaac
    19921 atgaataatt ataaacaaac accattggac tcacctccta aaaaaaattt cttcttaact
    19981 gttgtgtacc acatatgtcg gcaagttgca atagctactt tgcataaatt taagatattt
    20041 tgtgcaattt ttcatacgcc tgttaagttg ctaagtatag tatccagagt tttcgtactc
    20101 attataacca tacactacta cagcgtgttg ccctgcattt ggcaaatctc caaaaagaat
    20161 acaaggcctt ttgttgtttt tgatttcacc tgtaattccc cagcagccaa cagcctaact
    20221 tgcattttga ggaagggatc tgtttttaca gaaagtattc attactcttg caaaaaagtt
    20281 cacccggatt tccgaactga cgccggaagt cctgcacacc ttcattgaca aaatcgttgt
    20341 ccacgagcgc gcagaacgct acaagcaaaa gtccgagcag cagattgata tctacttcac
    20401 gcacatcgga aacttgaatg agttttagcc acaaaaccac cgcaggacag gcggcgcata
    20461 agcacttcct gtcctgcaat gtccttcttt tacagatact ttaactgaaa ctccggattc
    20521 cctttctcgt caatttctgc aacaatataa ctaggatcat gtcc
//
