Select genomic region:
Overview
4.1
6.1
8.1
8.2

### Identified secondary metabolite regions using strictness 'relaxed'

c00004_NZ_CABK.. (original name was: NZ_CABKNR010000009.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 4.1 | cyclic-lactone-autoinducer | 19,948 | 40,511 |

c00006_NZ_CABK.. (original name was: NZ_CABKNR010000011.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 6.1 | cyclic-lactone-autoinducer | 7,572 | 31,420 |

c00008_NZ_CABK.. (original name was: NZ_CABKNR010000013.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 8.1 | ranthipeptide | 61,064 | 82,707 |
Region 8.2 | cyclic-lactone-autoinducer | 201,080 | 221,874 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 4.1 | cyclic-lactone-autoinducer | 19,948 | 40,511 |
Region 6.1 | cyclic-lactone-autoinducer | 7,572 | 31,420 |
Region 8.1 | ranthipeptide | 61,064 | 82,707 |
Region 8.2 | cyclic-lactone-autoinducer | 201,080 | 221,874 |

No secondary metabolite regions were found in these records:
  c00001_NZ_CABK.. (original name was: NZ_CABKNR010000004.1)
  c00002_NZ_CABK.. (original name was: NZ_CABKNR010000007.1)
  c00003_NZ_CABK.. (original name was: NZ_CABKNR010000008.1)
  c00005_NZ_CABK.. (original name was: NZ_CABKNR010000010.1)
  c00007_NZ_CABK.. (original name was: NZ_CABKNR010000012.1)
  c00009_NZ_CABK.. (original name was: NZ_CABKNR010000014.1)
  c00010_NZ_CABK.. (original name was: NZ_CABKNR010000015.1)
  c00011_NZ_CABK.. (original name was: NZ_CABKNR010000016.1)
  c00012_NZ_CABK.. (original name was: NZ_CABKNR010000018.1)
  c00013_NZ_CABK.. (original name was: NZ_CABKNR010000019.1)
  c00014_NZ_CABK.. (original name was: NZ_CABKNR010000021.1)
  c00015_NZ_CABK.. (original name was: NZ_CABKNR010000022.1)
  c00016_NZ_CABK.. (original name was: NZ_CABKNR010000023.1)
  c00017_NZ_CABK.. (original name was: NZ_CABKNR010000024.1)
  c00018_NZ_CABK.. (original name was: NZ_CABKNR010000027.1)
  c00019_NZ_CABK.. (original name was: NZ_CABKNR010000029.1)
  c00020_NZ_CABK.. (original name was: NZ_CABKNR010000030.1)
  c00021_NZ_CABK.. (original name was: NZ_CABKNR010000031.1)

Compact view
c00004_NZ_CABK.. - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 19,948 - 40,511 nt. (total: 20,564 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002031.1 |  | 0.18 | Alkaloid | kitasetaline | Kitasatospora setae KM-6054
BGC0001914.1 |  | 0.17 | Other | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18
BGC0001529.1 |  | 0.17 | Alkaloid | bezastatin derivates | Streptomyces sp. RI18
BGC0001551.1 |  | 0.16 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0001618.1 |  | 0.16 | RiPP | hyicin 3682 | Staphylococcus hyicus
BGC0000616.1 |  | 0.15 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000522.1 |  | 0.15 | RiPP | lacticin Z | Lactococcus lactis
BGC0000560.1 |  | 0.15 | RiPP | subtilomycin | Bacillus subtilis
BGC0000620.1 |  | 0.15 | RiPP | lacticin Q | Lactococcus lactis
BGC0001684.1 |  | 0.15 | Other | N-acyloxyacyl glutamine | Klebsiella variicola

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002031.1 |  | 0.49 | Alkaloid | kitasetaline | Kitasatospora setae KM-6054
BGC0001914.1 |  | 0.48 | Other | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18
BGC0001529.1 |  | 0.48 | Alkaloid | bezastatin derivates | Streptomyces sp. RI18
BGC0001551.1 |  | 0.46 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0001618.1 |  | 0.46 | RiPP | hyicin 3682 | Staphylococcus hyicus
BGC0000616.1 |  | 0.46 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000522.1 |  | 0.45 | RiPP | lacticin Z | Lactococcus lactis
BGC0000560.1 |  | 0.45 | RiPP | subtilomycin | Bacillus subtilis
BGC0000620.1 |  | 0.45 | RiPP | lacticin Q | Lactococcus lactis
BGC0001684.1 |  | 0.45 | Other | N-acyloxyacyl glutamine | Klebsiella variicola

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00006_NZ_CABK.. - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 7,572 - 31,420 nt. (total: 23,849 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000758.1 |  | 0.13 | Saccharide | capsular polysaccharide | Staphylococcus aureus
BGC0000624.1 |  | 0.12 | RiPP | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0001751.1 |  | 0.04 | NRP, Polyketide | pyxipyrrolone A, pyxipyrrolone B | Pyxidicoccus sp. MCy9557
BGC0001728.1 |  | 0.04 | NRP, Polyketide | paenilipoheptin | Paenibacillus polymyxa E681
BGC0000268.1 |  | 0.04 | Polyketide | Sch-47554, Sch-47555 | Streptomyces sp. SCC 2136

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000758.1 |  | 0.42 | Saccharide | capsular polysaccharide | Staphylococcus aureus
BGC0000624.1 |  | 0.39 | RiPP | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0001751.1 |  | 0.19 | NRP, Polyketide | pyxipyrrolone A, pyxipyrrolone B | Pyxidicoccus sp. MCy9557
BGC0001728.1 |  | 0.19 | NRP, Polyketide | paenilipoheptin | Paenibacillus polymyxa E681
BGC0000268.1 |  | 0.17 | Polyketide | Sch-47554, Sch-47555 | Streptomyces sp. SCC 2136

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00008_NZ_CABK.. - Region 1 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 61,064 - 82,707 nt. (total: 21,644 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000602.1 |  | 0.19 | RiPP | subtilosin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001387.1 |  | 0.17 | Other | nucleocidin | Streptomyces calvus
BGC0000486.1 |  | 0.16 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0000500.1 |  | 0.16 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000616.1 |  | 0.16 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000504.1 |  | 0.16 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0001229.1 |  | 0.15 | RiPP | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0001222.1 |  | 0.15 | RiPP | acidocin B | Lactobacillus acidophilus
BGC0000491.1 |  | 0.15 | RiPP | gassericin A | Lactobacillus gasseri
BGC0001639.1 |  | 0.15 | RiPP | klebsidin | Klebsiella pneumoniae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000602.1 |  | 0.51 | RiPP | subtilosin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001387.1 |  | 0.48 | Other | nucleocidin | Streptomyces calvus
BGC0000486.1 |  | 0.46 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0000500.1 |  | 0.46 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000616.1 |  | 0.46 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000504.1 |  | 0.46 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0001229.1 |  | 0.46 | RiPP | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0001222.1 |  | 0.46 | RiPP | acidocin B | Lactobacillus acidophilus
BGC0000491.1 |  | 0.46 | RiPP | gassericin A | Lactobacillus gasseri
BGC0001639.1 |  | 0.45 | RiPP | klebsidin | Klebsiella pneumoniae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00008_NZ_CABK.. - Region 2 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 201,080 - 221,874 nt. (total: 20,795 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000488.1 |  | 0.21 | RiPP | circularin A | Clostridium beijerinckii
BGC0000539.1 |  | 0.18 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0000521.1 |  | 0.17 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000504.1 |  | 0.17 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000543.1 |  | 0.16 | RiPP | pep5 | Staphylococcus epidermidis
BGC0001526.1 |  | 0.16 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0000548.1 |  | 0.16 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000500.1 |  | 0.16 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000489.1 |  | 0.16 | RiPP | enterocin AS-48 | Enterococcus faecalis
BGC0000552.1 |  | 0.16 | RiPP | SmbA, SmbB | Streptococcus mutans

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000488.1 |  | 0.54 | RiPP | circularin A | Clostridium beijerinckii
BGC0000539.1 |  | 0.49 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0000521.1 |  | 0.48 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000504.1 |  | 0.48 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000543.1 |  | 0.47 | RiPP | pep5 | Staphylococcus epidermidis
BGC0001526.1 |  | 0.47 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0000548.1 |  | 0.47 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000500.1 |  | 0.46 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000489.1 |  | 0.46 | RiPP | enterocin AS-48 | Enterococcus faecalis
BGC0000552.1 |  | 0.46 | RiPP | SmbA, SmbB | Streptococcus mutans

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names