LOCUS       c00115_NZ_JAMD..        2645 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAMDNA010000125.1 Paenibacillus alvei strain NRRL B-04300
            contig_0000125, whole genome shotgun sequence.
ACCESSION   c00115_NZ_JAMD..
VERSION     c00115_NZ_JAMD..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:57:11
            Original ID  :: NZ_JAMDNA010000125.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2645
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2645
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:1711](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2..1711)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2645
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2645
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     PFAM_domain     complement(2..265)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg115_1_0002"
                     /evalue="4.40E-25"
                     /label="ctg115_1"
                     /locus_tag="ctg115_1"
                     /protein_end="570"
                     /protein_start="482"
                     /score="88.2"
                     /tool="antismash"
                     /translation="WEEQVAHTPDAIAVVYEDNDVTYDALNQKINQVAWALRRLHIKPD
                     DRVVIVAERSVEMIAGMYGIIKAGGAYVPVDPTLPAERMQFIL"
     CDS             complement(2..1711)
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (7-34). E-value: 5.1e-13.
                     Score: 39.9. Matches aSDomain:
                     nrpspksdomains_ctg115_1_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (11-319). E-value:
                     1.5e-93. Score: 305.0. Matches aSDomain:
                     nrpspksdomains_ctg115_1_Condensation_DCL.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     255.7; E-value: 1.7e-77)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg115_1"
                     /sec_met_domain="Condensation (E-value: 2.6e-74, bitscore:
                     237.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8.9e-26, bitscore:
                     77.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSKMVLGSKIENIYSLTPVQEGMLFHKLMNGDSTAYVVQHRFEL
                     NGLINEQKVKEAIQLVTMKHDVLRTSIVFEKLTVPRQIILKNRAIEYERIDLSDIAAYE
                     RNNKMDMIAQLDVERGFDLQRDSLLRVKLVHFGANQYKMLWTFHHIIIDGWSLSILFSD
                     FKTYYDMLEHGKSLQSIMSIVETDKKRIEKYGDYVKWLEQQNANEGIAYWEELLSDYDG
                     AADIKSTEQTPLAVETVSLSEMKLSKEQTASLQNLAATHHITMNTIVETAWGIVLQLYT
                     GAKDVVYGKVISGRHVPIRGIEKIVGPFIVTIPARIRYKEDDIVLEVLHSTQLQGTKST
                     AYSYCPLQQIMSLTKQKSELIKYLYAFENYELDETLLTQHSEGLGLNIETYREQTNYDL
                     VLIANYEHGYLRFQMQYASNRYGSKEIEAMLLRLQVVLLSFVNTPEMKLSELETITEEE
                     KEQILGAFNDTSLPYAKDKTIPALWEEQVAHTPDAIAVVYEDNDVTYDALNQKINQVAW
                     ALRRLHIKPDDRVVIVAERSVEMIAGMYGIIKAGGAYVPVDPTLPAERMQFIL"
     CDS_motif       complement(38..76)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0006"
                     /evalue="4.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg115_1"
                     /protein_end="558"
                     /protein_start="545"
                     /score="16.6"
                     /tool="antismash"
                     /translation="GIIKAGGAYVPVD"
     PFAM_domain     complement(323..1678)
                     /aSDomain="Condensation"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00668.22"
                     /description="Condensation domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg115_1_0001"
                     /evalue="8.70E-93"
                     /label="ctg115_1"
                     /locus_tag="ctg115_1"
                     /protein_end="463"
                     /protein_start="11"
                     /score="311.6"
                     /tool="antismash"
                     /translation="ENIYSLTPVQEGMLFHKLMNGDSTAYVVQHRFELNGLINEQKVKE
                     AIQLVTMKHDVLRTSIVFEKLTVPRQIILKNRAIEYERIDLSDIAAYERNNKMDMIAQL
                     DVERGFDLQRDSLLRVKLVHFGANQYKMLWTFHHIIIDGWSLSILFSDFKTYYDMLEHG
                     KSLQSIMSIVETDKKRIEKYGDYVKWLEQQNANEGIAYWEELLSDYDGAADIKSTEQTP
                     LAVETVSLSEMKLSKEQTASLQNLAATHHITMNTIVETAWGIVLQLYTGAKDVVYGKVI
                     SGRHVPIRGIEKIVGPFIVTIPARIRYKEDDIVLEVLHSTQLQGTKSTAYSYCPLQQIM
                     SLTKQKSELIKYLYAFENYELDETLLTQHSEGLGLNIETYREQTNYDLVLIANYEHGYL
                     RFQMQYASNRYGSKEIEAMLLRLQVVLLSFVNTPEMKLSELETITEEEKEQIL"
     CDS_motif       complement(602..700)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0005"
                     /evalue="2.20E-05"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg115_1"
                     /protein_end="370"
                     /protein_start="337"
                     /score="16.8"
                     /tool="antismash"
                     /translation="KSTAYSYCPLQQIMSLTKQKSELIKYLYAFENY"
     aSDomain        complement(755..1678)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg115_1_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="1.50E-93"
                     /label="ctg115_1_Condensation_DCL.1"
                     /locus_tag="ctg115_1"
                     /protein_end="319"
                     /protein_start="11"
                     /score="305.0"
                     /tool="antismash"
                     /translation="ENIYSLTPVQEGMLFHKLMNGDSTAYVVQHRFELNGLINEQKVKE
                     AIQLVTMKHDVLRTSIVFEKLTVPRQIILKNRAIEYERIDLSDIAAYERNNKMDMIAQL
                     DVERGFDLQRDSLLRVKLVHFGANQYKMLWTFHHIIIDGWSLSILFSDFKTYYDMLEHG
                     KSLQSIMSIVETDKKRIEKYGDYVKWLEQQNANEGIAYWEELLSDYDGAADIKSTEQTP
                     LAVETVSLSEMKLSKEQTASLQNLAATHHITMNTIVETAWGIVLQLYTGAKDVVYGKVI
                     SGRHVPIRGIEKIVGPFIVTIPARIRY"
     CDS_motif       complement(764..859)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0004"
                     /evalue="4.80E-12"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg115_1"
                     /protein_end="316"
                     /protein_start="284"
                     /score="38.3"
                     /tool="antismash"
                     /translation="DVVYGKVISGRHVPIRGIEKIVGPFIVTIPAR"
     CDS_motif       complement(1208..1273)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0003"
                     /evalue="3.90E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg115_1"
                     /protein_end="168"
                     /protein_start="146"
                     /score="32.1"
                     /tool="antismash"
                     /translation="FHHIIIDGWSLSILFSDFKTYY"
     CDS_motif       complement(1496..1609)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0002"
                     /evalue="1.90E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg115_1"
                     /protein_end="72"
                     /protein_start="34"
                     /score="23.5"
                     /tool="antismash"
                     /translation="TAYVVQHRFELNGLINEQKVKEAIQLVTMKHDVLRTSI"
     aSDomain        complement(1610..1690)
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg115_1_NRPS-COM_Nterm.1"
                     /evalue="5.10E-13"
                     /label="ctg115_1_NRPS-COM_Nterm.1"
                     /locus_tag="ctg115_1"
                     /protein_end="34"
                     /protein_start="7"
                     /score="39.9"
                     /tool="antismash"
                     /translation="GSKIENIYSLTPVQEGMLFHKLMNGDS"
     CDS_motif       complement(1631..1669)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_1_0001"
                     /evalue="3.50E-05"
                     /label="C1_dual_004-017"
                     /locus_tag="ctg115_1"
                     /protein_end="27"
                     /protein_start="14"
                     /score="16.4"
                     /tool="antismash"
                     /translation="YSLTPVQEGMLFH"
     CDS             complement(1738..2643)
                     /NRPS_PKS="Domain: TIGR01720 (151-292). E-value: 8.1e-29.
                     Score: 92.3. Matches aSDomain:
                     nrpspksdomains_ctg115_2_TIGR01720.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     59.4; E-value: 6.3e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg115_2"
                     /sec_met_domain="Condensation (E-value: 2.4e-33, bitscore:
                     102.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IQQVKEGTKIRFPAKTASYKAWAEALAEYKDSHLLQKERAYWEQV
                     ATQMAAGELWMDEQTGESGYDSCTIHLNEKETEQLIHQASRAYNTEINDLLISALGMTV
                     KKLTGARDVTIGMEGHGREPIHKRIDIDRTVGWFTSIYPVVVPCHEDIAESIITTKETL
                     RQIPNRGLGYGLLQDELPVRPLEVMFNYMGQMDAEAKGKKLHFFSSGKGSADENIVYRK
                     VNINGSLLKEQLHFSIVYDKSKLSAEKIQLFIETFHDCLMATIQFCASQEEVAITISDT
                     DATDLVVDDLQVINELFDLE"
     aSDomain        complement(1768..2190)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg115_2_TIGR01720.1"
                     /evalue="8.10E-29"
                     /label="ctg115_2_TIGR01720.1"
                     /locus_tag="ctg115_2"
                     /protein_end="292"
                     /protein_start="151"
                     /score="92.3"
                     /tool="antismash"
                     /translation="IAESIITTKETLRQIPNRGLGYGLLQDELPVRPLEVMFNYMGQMD
                     AEAKGKKLHFFSSGKGSADENIVYRKVNINGSLLKEQLHFSIVYDKSKLSAEKIQLFIE
                     TFHDCLMATIQFCASQEEVAITISDTDATDLVVDDLQ"
     aSDomain        complement(1768..2190)
                     /aSDomain="TIGR01720"
                     /aSTool="tigrfam"
                     /description="NRPS-para261: non-ribosomal peptide synthase
                     domain TIGR01720"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg115_2_0001"
                     /evalue="6.60E-27"
                     /identifier="TIGR01720"
                     /label="ctg115_2"
                     /locus_tag="ctg115_2"
                     /protein_end="292"
                     /protein_start="151"
                     /score="92.3"
                     /tool="antismash"
                     /translation="IAESIITTKETLRQIPNRGLGYGLLQDELPVRPLEVMFNYMGQMD
                     AEAKGKKLHFFSSGKGSADENIVYRKVNINGSLLKEQLHFSIVYDKSKLSAEKIQLFIE
                     TFHDCLMATIQFCASQEEVAITISDTDATDLVVDDLQ"
     PFAM_domain     complement(1786..2640)
                     /aSDomain="Condensation"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00668.22"
                     /description="Condensation domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg115_2_0003"
                     /evalue="2.10E-46"
                     /label="ctg115_2"
                     /locus_tag="ctg115_2"
                     /protein_end="286"
                     /protein_start="1"
                     /score="158.7"
                     /tool="antismash"
                     /translation="QQVKEGTKIRFPAKTASYKAWAEALAEYKDSHLLQKERAYWEQVA
                     TQMAAGELWMDEQTGESGYDSCTIHLNEKETEQLIHQASRAYNTEINDLLISALGMTVK
                     KLTGARDVTIGMEGHGREPIHKRIDIDRTVGWFTSIYPVVVPCHEDIAESIITTKETLR
                     QIPNRGLGYGLLQDELPVRPLEVMFNYMGQMDAEAKGKKLHFFSSGKGSADENIVYRKV
                     NINGSLLKEQLHFSIVYDKSKLSAEKIQLFIETFHDCLMATIQFCASQEEVAITISDTD
                     ATDL"
     CDS_motif       complement(2116..2169)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_2_0002"
                     /evalue="3.00E-09"
                     /label="NRPS-E6"
                     /locus_tag="ctg115_2"
                     /protein_end="176"
                     /protein_start="158"
                     /score="29.1"
                     /tool="antismash"
                     /translation="TKETLRQIPNRGLGYGLL"
     CDS_motif       complement(2206..2256)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg115_2_0001"
                     /evalue="2.80E-09"
                     /label="NRPS-E5"
                     /locus_tag="ctg115_2"
                     /protein_end="146"
                     /protein_start="129"
                     /score="28.8"
                     /tool="antismash"
                     /translation="DIDRTVGWFTSIYPVVV"
ORIGIN
        1 ttaggataaa ctgcatacgc tctgctggga gggtaggatc gactggcaca tacgcgccac
       61 ctgccttgat gatgccatac atcccggcaa tcatctccac acttcgctct gctacgatta
      121 ccacgcggtc atccggttta atgtgcagtc tgcgaagcgc ccatgccact tggttgattt
      181 tttggtttaa tgcgtcatac gtcacatcgt tgtcttcata tacaacggcg atggcatccg
      241 gggtgtgagc aacctgctct tcccataatg ctggaatcgt tttatccttt gcatacggta
      301 agctcgtatc attaaatgca cctagtatct gttctttctc ttcctctgtt atcgtctcaa
      361 gttcagacaa cttcatttct ggggtgttga cgaaagagag taagacaact tgtaagcgca
      421 ataacattgc ttctatttcc tttgatccat agcgatttga cgcatactgc atctgaaaac
      481 gcaaataccc gtgttcataa tttgcgatta agactaaatc ataattcgtt tgctcccgat
      541 aagtttctat atttaaccca agtccctcac tgtgctgtgt caataaagtc tcatcaagct
      601 cataattttc aaaggcatat aaatacttga tcaactctga tttttgcttc gttaaactca
      661 taatctgctg taagggacaa taagaataag ctgtactttt cgttccttgt agctgcgtgc
      721 tgtgcaaaac ttctaaaact atatcatctt ctttatacct gattcttgcg ggaatcgtca
      781 cgataaatgg acccacaatc ttttcaattc ctctaattgg aacatgcctg cctgaaatta
      841 ccttgccata aacaacatct ttggcacctg tatacaattg cagtacaatt ccccaggctg
      901 tttccacaat cgtattcatc gtaatatgat gggtggcagc gagattttgc aaacttgccg
      961 tctgttcttt agataatttc atttcactca aagaaacggt ttccaccgct aatggcgttt
     1021 gctccgttga ctttatgtcc gctgctccat catagtcaga taataattct tcccaatacg
     1081 caatgccttc attagcattt tgctgctcca gccactttac ataatctcca tatttttcga
     1141 ttctcttctt gtcagtttcc actatcgaca tgatagattg caagctcttt ccatgttcaa
     1201 gcatgtcata atacgttttg aaatcactga acaaaataga taagctccaa ccatcaataa
     1261 tgatgtgatg aaaagtccat aacatcttat attggtttgc tccaaaatga acgagcttga
     1321 ctcttaataa agaatcgcgt tgtagatcaa acccgcgctc cacatcaagt tgcgcaatca
     1381 tatccatttt attgtttcgt tcatatgccg caatatccga taaatctatc cgttcatatt
     1441 ctattgcccg gttcttgagt ataatttgtc tcggcacagt caatttctca aatacgatgg
     1501 aagttcttaa aacgtcatgc ttcatcgtta caagttgtat tgcctctttt accttttgtt
     1561 cattaatcag accgttcagt tcaaaacgat gctgaacgac ataagcggta gaatcaccat
     1621 tcatcagctt atgaaacagc attccttctt gtactggggt aagagaataa atattctcaa
     1681 ttttagaacc taaaaccatt ttcgagctca tgtctgctcc tccaccttat agtagattta
     1741 ttctagatcg aatagctcat ttatcacttg gagatcgtcc acaaccaaat cagtggcatc
     1801 cgtatccgag atcgtgatgg caacctcctc ctgtgatgca caaaattgaa tcgtagccat
     1861 taaacaatca tggaatgttt caataaatag ttgtatcttc tcagcagaca acttgctctt
     1921 gtcatagaca atactgaaat gcaactgttc ttttagcaag cttccgttaa tattgacttt
     1981 acggtataca atattttcat ccgctgatcc cttgcccgaa ctaaagaagt gtagtttttt
     2041 ccccttcgct tcagcgtcca tttgccccat gtagttaaac atgacttcaa gcggccggac
     2101 tggcaattca tcctgtaata gaccgtatcc aaggcctcgg ttcgggattt gacgcagcgt
     2161 ctctttggtt gtaatgatac tttctgctat atcctcatga cacggaacca cgactggata
     2221 tatacttgta aaccatccga ccgtccggtc gatatcgatc cgcttatgaa tcggttctct
     2281 tccgtgtcct tccatgccta tcgttacatc tcttgcccct gttagtttct tcacggtcat
     2341 tcccagggcg ctaataagca agtcattgat ctcggtatta tatgcccgac ttgcctggtg
     2401 gatcagctgc tcggtttctt tttcatttaa atgtatcgtg caactgtcat aaccgctttc
     2461 tcctgtctgt tcgtccatcc agagttcgcc tgccgccatc tgcgtggcta cttgttccca
     2521 gtacgcccgt tctttctgca agaggtggct gtccttatat tctgccaacg cctccgccca
     2581 tgccttatat gacgctgtct ttgccgggaa tcggatcttg gttccttctt ttacttgctg
     2641 gatag
//
