LOCUS       NC_009437.1            21340 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_009437.1 Caldicellulosiruptor saccharolyticus DSM 8903, complete
            sequence.
ACCESSION   NC_009437
VERSION     NC_009437.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:29:42
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2403391
            Orig. end    :: 2424731
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21340
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2413391:2414731]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11340
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21340
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21340
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="4"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             complement(409..699)
                     /locus_tag="ctg1_2361"
                     /transl_table=11
                     /translation="MLPEEIIKRPIITEKSMSMIPQKKYTFEVDRRANKIEIKKAVEQL
                     FGVEVEKVWTMNVKPKRKRVGRFEGRTKAWKKAIVKLTDKSKTIEFFDSLI"
     PFAM_domain     complement(436..684)
                     /aSDomain="Ribosomal_L23"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00276.22"
                     /description="Ribosomal protein L23"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2361_0050"
                     /evalue="2.20E-34"
                     /label="ctg1_2361"
                     /locus_tag="ctg1_2361"
                     /protein_end="88"
                     /protein_start="5"
                     /score="117.7"
                     /tool="antismash"
                     /translation="IIKRPIITEKSMSMIPQKKYTFEVDRRANKIEIKKAVEQLFGVEV
                     EKVWTMNVKPKRKRVGRFEGRTKAWKKAIVKLTDKSKT"
     CDS             complement(701..1327)
                     /locus_tag="ctg1_2362"
                     /transl_table=11
                     /translation="MPKVPVYNIEGQQIGEIELNDSIFNVPINTHVLHQAVVAHLANRR
                     QGTFAAKTRAEVRGGGRKPWRQKGTGRARQGSIRAPTWRKGGVVFAKKPRDFSIDLPKK
                     VRRLALKCALSSKVKENNLIVLDKWDMNQYRTKEVIRVLKNLGLENEKALIVIPEKNEY
                     LQKSTKNIPEVKTLQVGNLNVFDILKYDKFIILQDAVKKVEEVYA"
     aSDomain        complement(713..1279)
                     /aSDomain="TIGR03953"
                     /aSTool="tigrfam"
                     /description="rplD_bact: 50S ribosomal protein uL4"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2362_0023"
                     /evalue="1.60E-77"
                     /identifier="TIGR03953"
                     /label="ctg1_2362"
                     /locus_tag="ctg1_2362"
                     /protein_end="205"
                     /protein_start="16"
                     /score="257.0"
                     /tool="antismash"
                     /translation="IELNDSIFNVPINTHVLHQAVVAHLANRRQGTFAAKTRAEVRGGG
                     RKPWRQKGTGRARQGSIRAPTWRKGGVVFAKKPRDFSIDLPKKVRRLALKCALSSKVKE
                     NNLIVLDKWDMNQYRTKEVIRVLKNLGLENEKALIVIPEKNEYLQKSTKNIPEVKTLQV
                     GNLNVFDILKYDKFIILQDAVKKVEE"
     PFAM_domain     complement(713..1279)
                     /aSDomain="Ribosomal_L4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00573.24"
                     /description="Ribosomal protein L4/L1 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2362_0051"
                     /evalue="7.10E-71"
                     /label="ctg1_2362"
                     /locus_tag="ctg1_2362"
                     /protein_end="205"
                     /protein_start="16"
                     /score="238.0"
                     /tool="antismash"
                     /translation="IELNDSIFNVPINTHVLHQAVVAHLANRRQGTFAAKTRAEVRGGG
                     RKPWRQKGTGRARQGSIRAPTWRKGGVVFAKKPRDFSIDLPKKVRRLALKCALSSKVKE
                     NNLIVLDKWDMNQYRTKEVIRVLKNLGLENEKALIVIPEKNEYLQKSTKNIPEVKTLQV
                     GNLNVFDILKYDKFIILQDAVKKVEE"
     CDS             complement(1357..1989)
                     /locus_tag="ctg1_2363"
                     /transl_table=11
                     /translation="MTKGILGKKIGMTQVFDEAGKVVPVTVIEAGPCVVVQKKTVEKDG
                     YAAIQVGFEDIKETKLNKPLRGHFAKHGVKPKRYLRELRLKDADKYEVGQEIRVDIFSP
                     GERVDVTGISKAKGFQGVIKRHGQQRGPMSHGSMYHRRVGSMGSNTFPARTFPGKKMPG
                     RMGGQRVTVLNLQVVKVDPERNLLLVKGSVPGNKNSLLIIRDSVKSK"
     aSDomain        complement(1378..1980)
                     /aSDomain="TIGR03625"
                     /aSTool="tigrfam"
                     /description="L3_bact: 50S ribosomal protein uL3"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2363_0024"
                     /evalue="3.80E-90"
                     /identifier="TIGR03625"
                     /label="ctg1_2363"
                     /locus_tag="ctg1_2363"
                     /protein_end="204"
                     /protein_start="3"
                     /score="299.1"
                     /tool="antismash"
                     /translation="GILGKKIGMTQVFDEAGKVVPVTVIEAGPCVVVQKKTVEKDGYAA
                     IQVGFEDIKETKLNKPLRGHFAKHGVKPKRYLRELRLKDADKYEVGQEIRVDIFSPGER
                     VDVTGISKAKGFQGVIKRHGQQRGPMSHGSMYHRRVGSMGSNTFPARTFPGKKMPGRMG
                     GQRVTVLNLQVVKVDPERNLLLVKGSVPGNKNSLLIIR"
     PFAM_domain     complement(1447..1695)
                     /aSDomain="Ribosomal_L3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00297.24"
                     /description="Ribosomal protein L3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2363_0052"
                     /evalue="6.50E-15"
                     /label="ctg1_2363"
                     /locus_tag="ctg1_2363"
                     /protein_end="181"
                     /protein_start="98"
                     /score="55.1"
                     /tool="antismash"
                     /translation="VDIFSPGERVDVTGISKAKGFQGVIKRHGQQRGPMSHGSMYHRRV
                     GSMGSNTFPARTFPGKKMPGRMGGQRVTVLNLQVVKVD"
     CDS             complement(1996..2316)
                     /locus_tag="ctg1_2364"
                     /transl_table=11
                     /translation="MSKAQRMRIKLKSFDYKLLDQSARKIVETAKSTGAEVSGPVPLPT
                     DREVITIIRAPHKYKDSREQFEIKTHKRLIDIIKPTQKTVDALMRVELPAGVDIEIKLK
                     EV"
     PFAM_domain     complement(2011..2295)
                     /aSDomain="Ribosomal_S10"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00338.24"
                     /description="Ribosomal protein S10p/S20e"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2364_0053"
                     /evalue="1.10E-35"
                     /label="ctg1_2364"
                     /locus_tag="ctg1_2364"
                     /protein_end="102"
                     /protein_start="7"
                     /score="121.8"
                     /tool="antismash"
                     /translation="RIKLKSFDYKLLDQSARKIVETAKSTGAEVSGPVPLPTDREVITI
                     IRAPHKYKDSREQFEIKTHKRLIDIIKPTQKTVDALMRVELPAGVDIEIK"
     aSDomain        complement(2011..2304)
                     /aSDomain="TIGR01049"
                     /aSTool="tigrfam"
                     /description="rpsJ_bact: ribosomal protein uS10"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2364_0025"
                     /evalue="1.50E-45"
                     /identifier="TIGR01049"
                     /label="ctg1_2364"
                     /locus_tag="ctg1_2364"
                     /protein_end="102"
                     /protein_start="4"
                     /score="151.4"
                     /tool="antismash"
                     /translation="QRMRIKLKSFDYKLLDQSARKIVETAKSTGAEVSGPVPLPTDREV
                     ITIIRAPHKYKDSREQFEIKTHKRLIDIIKPTQKTVDALMRVELPAGVDIEIK"
     CDS             2823..3923
                     /locus_tag="ctg1_2365"
                     /transl_table=11
                     /translation="MNIISYHELRKISPQKARELVRKVFESNNKNVSKTAKILGVSRHT
                     VRRAVYGPLEDKSKKPKSSPKKLSSELENFIVEESKKTGFRYRRLSFYLLRKYGIKISE
                     NTIKSILRRNSVARKTKRTKKGERSLYDYETLIPFSEFQLDTKHLLDKESLPKEVYEHM
                     KRYNLPCYEWNIIDVATRTRFTAYSYELSSAFGFMFISLVALWLRTHNVRNIIKIRLDN
                     GAEFCGGSERKLKQWNEMLSFLGVELNPIPPKAKHLMGIIENSHRADDEYFLMIHAERC
                     KTKDEFIQRAQKWQDTWNFFRPHNGKGMNGRTPFEKFIASKSLVSSHIFQFPTLLLEDI
                     MKKVGTFYSLFCNKFGGKYVFTTYQF"
     CDS             complement(3920..4081)
                     /locus_tag="ctg1_2366"
                     /transl_table=11
                     /translation="MQEKYVCGICGYEIVDLNSPCPYCGAEPNHFVKADEVDVELIKKI
                     YQEGGATY"
     CDS             complement(4141..4647)
                     /locus_tag="ctg1_2367"
                     /transl_table=11
                     /translation="MDWTKFAYDAPYPEPKVEEPNRHYAEILLDDYAGYASEFTAIALY
                     SYQHFISDVRNKDFAELIIGIARVEMKHLDLLGTTIYLLGALPKYRGSYTTYGQYWNGY
                     FVNYDKDLKDMIKIDIQSEKEAIKNYKRHIEMIDDRYIRKLLERIILDEEKHIKLLKDY
                     LDRKF"
     PFAM_domain     complement(4153..4542)
                     /aSDomain="Ferritin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00210.26"
                     /description="Ferritin-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2367_0054"
                     /evalue="7.10E-13"
                     /label="ctg1_2367"
                     /locus_tag="ctg1_2367"
                     /protein_end="165"
                     /protein_start="35"
                     /score="48.8"
                     /tool="antismash"
                     /translation="ASEFTAIALYSYQHFISDVRNKDFAELIIGIARVEMKHLDLLGTT
                     IYLLGALPKYRGSYTTYGQYWNGYFVNYDKDLKDMIKIDIQSEKEAIKNYKRHIEMIDD
                     RYIRKLLERIILDEEKHIKLLKDYLD"
     CDS             4863..6041
                     /locus_tag="ctg1_2368"
                     /transl_table=11
                     /translation="MKIGVGNLLLSISYLIDIAQGRKEHAPKVTYISLQIAKQLQIEKN
                     ETKKIYYASFLHDIGITVSDNNFYASHVDIQLAKNHCLLGYEFVRKLPLDEEISEIIKY
                     HHDFYNGSGAFGYDYRVLPLASQIINLADQIDISMNWSNPYYLQVDDLKEWVKKNKGIL
                     FNPFIVDAFLDIADKDKFWLDLYNPQLRQIILELLPDEEVYFDIKTMLKFSEAVALLID
                     NKSKFTHLHSQGLSEVVFEIAKIMGLDHETSNKLKIAGYLHDLGKMVVPNEILNKVGKL
                     TKEEFYIIKSHPYYTKLILDQIPVFKGEISNWAGNHHERIDRSGYPEKLGKDELSLLDR
                     VVGICDVYQALIEDRPYRKGLGQKEALSIIYDMVKNELFLEEEFELLRRAVV"
     aSDomain        4920..5180
                     /aSDomain="TIGR00277"
                     /aSTool="tigrfam"
                     /description="HDIG: HDIG domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2368_0026"
                     /evalue="5.70E-08"
                     /identifier="TIGR00277"
                     /label="ctg1_2368"
                     /locus_tag="ctg1_2368"
                     /protein_end="106"
                     /protein_start="19"
                     /score="30.5"
                     /tool="antismash"
                     /translation="QGRKEHAPKVTYISLQIAKQLQIEKNETKKIYYASFLHDIGITVS
                     DNNFYASHVDIQLAKNHCLLGYEFVRKLPLDEEISEIIKYHH"
     PFAM_domain     4932..5270
                     /aSDomain="HD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01966.24"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2368_0055"
                     /evalue="2.90E-08"
                     /label="ctg1_2368"
                     /locus_tag="ctg1_2368"
                     /protein_end="136"
                     /protein_start="23"
                     /score="34.0"
                     /tool="antismash"
                     /translation="EHAPKVTYISLQIAKQLQIEKNETKKIYYASFLHDIGITVSDNNF
                     YASHVDIQLAKNHCLLGYEFVRKLPLDEEISEIIKYHHDFYNGSGAFGYDYRVLPLASQ
                     IINLADQID"
     PFAM_domain     5577..5912
                     /aSDomain="HD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01966.24"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2368_0056"
                     /evalue="2.40E-15"
                     /label="ctg1_2368"
                     /locus_tag="ctg1_2368"
                     /protein_end="350"
                     /protein_start="238"
                     /score="56.9"
                     /tool="antismash"
                     /translation="VFEIAKIMGLDHETSNKLKIAGYLHDLGKMVVPNEILNKVGKLTK
                     EEFYIIKSHPYYTKLILDQIPVFKGEISNWAGNHHERIDRSGYPEKLGKDELSLLDRVV
                     GICDVYQA"
     CDS             complement(6054..7421)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 176.4; E-value: 2.1e-53)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2369"
                     /transl_table=11
                     /translation="MKIRTKIYLSYLGLIVFIFATFSIIFYATFKSNLIEQVKTDNLRF
                     AKLVESFFINQSKNIKELKKFESYFETWGYKFLQDYIVIVTNDGSIEYSNKELDVEARV
                     KIMKLFNENKEFSYSFEIGQLQEKPYLFTLYKSKSNTHFFILIISDLERISIFQKRFFS
                     LIFQIAIFTALLAAAVSVFVSKQIIQGLLKLKEGIIEASKMRFNKKVEVGSRDEVGMIA
                     HEFNKLIEKISEYNQAQIRFLQNISHELKTPLTSIRGYAEVLKMGLLDVEKANHAANRI
                     IEHVDKLKILINQIIDLTKIESVENYFVFEKSNLEDILFDAVLDNEGYALSKGIKIVFE
                     PNTKIPVLCDREKLKEAFSNIISNCIRYAKSKVVVEIKLQKDEFEVRVEDDGVGFKNDE
                     IDKIFERFFKGKRGESGLGLSIAKAIFDKHGFAVKAENAEPVGARFVIKGSSYKEQ"
     PFAM_domain     complement(6081..6374)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2369_0058"
                     /evalue="2.80E-16"
                     /label="ctg1_2369"
                     /locus_tag="ctg1_2369"
                     /protein_end="447"
                     /protein_start="349"
                     /score="60.1"
                     /tool="antismash"
                     /translation="DREKLKEAFSNIISNCIRYAKSKVVVEIKLQKDEFEVRVEDDGVG
                     FKNDEIDKIFERFFKGKRGESGLGLSIAKAIFDKHGFAVKAENAEPVGARFVI"
     PFAM_domain     complement(6513..6704)
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2369_0057"
                     /evalue="2.40E-14"
                     /label="ctg1_2369"
                     /locus_tag="ctg1_2369"
                     /protein_end="303"
                     /protein_start="239"
                     /score="53.2"
                     /tool="antismash"
                     /translation="IRFLQNISHELKTPLTSIRGYAEVLKMGLLDVEKANHAANRIIEH
                     VDKLKILINQIIDLTKIES"
     CDS             complement(7405..8109)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 191.1; E-value: 3.3e-58)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2370"
                     /transl_table=11
                     /translation="MSRYLVYVVDDEKDILDIIYQYLISRGYEVKTFEDASSFLKEFEE
                     NEPDIVILDIMLPDIDGYELCKKIRKSSNVPIIMLSAKGEEFDKVLGLELGSDDYISKP
                     FSLLELEARIKKILRRVGKDTLKVDNALEFFGIKVDLNQKSVFYNNVKVDLSPKEFETF
                     LLLFREHSKVHKRSYILEQVWGDPALYDERMVDDVIKRLRKKILQYKLPIEIKTMWGLG
                     YKLEEKKDENQN"
     PFAM_domain     complement(7435..7656)
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2370_0060"
                     /evalue="1.40E-17"
                     /label="ctg1_2370"
                     /locus_tag="ctg1_2370"
                     /protein_end="225"
                     /protein_start="151"
                     /score="63.6"
                     /tool="antismash"
                     /translation="KVDLSPKEFETFLLLFREHSKVHKRSYILEQVWGDPALYDERMVD
                     DVIKRLRKKILQYKLPIEIKTMWGLGYKL"
     PFAM_domain     complement(7768..8094)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2370_0059"
                     /evalue="2.30E-29"
                     /label="ctg1_2370"
                     /locus_tag="ctg1_2370"
                     /protein_end="114"
                     /protein_start="5"
                     /score="101.9"
                     /tool="antismash"
                     /translation="VYVVDDEKDILDIIYQYLISRGYEVKTFEDASSFLKEFEENEPDI
                     VILDIMLPDIDGYELCKKIRKSSNVPIIMLSAKGEEFDKVLGLELGSDDYISKPFSLLE
                     LEARI"
     CDS             8271..9662
                     /locus_tag="ctg1_2371"
                     /transl_table=11
                     /translation="MIKFGTDGWRAVISKDYTFDNVKIVAQAIADYIKEIDDKRPVLVG
                     YDTRFMSEEYARLCAGVLVANGTKTYLTKKPTPTPVVSFTVKNMNLAGAIMITASHNPP
                     QWNGIKFKGDYGGSALPSIIAEIEKHLYKNEVKFVEPEESSLFSFIDADKDYFEHIEKL
                     VDLNLIAKFKPFAIIDPMHGAGVGYVKTLLEKYGIKHIQIRDERNPYFGGVNPEPIYKN
                     LGKLIDTVVQNNADIGLATDGDADRVGAVDEKGEFIDSHRIYALLLRHLVEAKGLKGGV
                     VKTFSTTNMVPILANKYGLKIYETPIGFKYICELFLKEDILIGGEESGGIGIKNHIPER
                     DGILCSLLLLEIMAYYQKPISQILDELFKEIGYHYYDRVDLHLPIEIKEKTLKMISQNT
                     EFAGRKIKEIQTLDGYKYIFEDGSWILFRASGTEPVLRVYTEQFTKDEVKRLLDEAVKL
                     IEEMK"
     PFAM_domain     8274..8672
                     /aSDomain="PGM_PMM_I"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02878.18"
                     /description="Phosphoglucomutase/phosphomannomutase,
                     alpha/beta/alpha domain I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2371_0061"
                     /evalue="6.00E-41"
                     /label="ctg1_2371"
                     /locus_tag="ctg1_2371"
                     /protein_end="134"
                     /protein_start="1"
                     /score="139.5"
                     /tool="antismash"
                     /translation="IKFGTDGWRAVISKDYTFDNVKIVAQAIADYIKEIDDKRPVLVGY
                     DTRFMSEEYARLCAGVLVANGTKTYLTKKPTPTPVVSFTVKNMNLAGAIMITASHNPPQ
                     WNGIKFKGDYGGSALPSIIAEIEKHLYKN"
     PFAM_domain     8733..9035
                     /aSDomain="PGM_PMM_II"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02879.18"
                     /description="Phosphoglucomutase/phosphomannomutase,
                     alpha/beta/alpha domain II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2371_0062"
                     /evalue="3.10E-25"
                     /label="ctg1_2371"
                     /locus_tag="ctg1_2371"
                     /protein_end="255"
                     /protein_start="154"
                     /score="88.9"
                     /tool="antismash"
                     /translation="DYFEHIEKLVDLNLIAKFKPFAIIDPMHGAGVGYVKTLLEKYGIK
                     HIQIRDERNPYFGGVNPEPIYKNLGKLIDTVVQNNADIGLATDGDADRVGAVDEKG"
     PFAM_domain     9048..9380
                     /aSDomain="PGM_PMM_III"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02880.18"
                     /description="Phosphoglucomutase/phosphomannomutase,
                     alpha/beta/alpha domain III"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2371_0063"
                     /evalue="1.20E-27"
                     /label="ctg1_2371"
                     /locus_tag="ctg1_2371"
                     /protein_end="370"
                     /protein_start="259"
                     /score="96.4"
                     /tool="antismash"
                     /translation="SHRIYALLLRHLVEAKGLKGGVVKTFSTTNMVPILANKYGLKIYE
                     TPIGFKYICELFLKEDILIGGEESGGIGIKNHIPERDGILCSLLLLEIMAYYQKPISQI
                     LDELFKE"
     PFAM_domain     9474..9650
                     /aSDomain="PGM_PMM_IV"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00408.22"
                     /description="Phosphoglucomutase/phosphomannomutase,
                     C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2371_0064"
                     /evalue="2.90E-14"
                     /label="ctg1_2371"
                     /locus_tag="ctg1_2371"
                     /protein_end="460"
                     /protein_start="401"
                     /score="53.1"
                     /tool="antismash"
                     /translation="AGRKIKEIQTLDGYKYIFEDGSWILFRASGTEPVLRVYTEQFTKD
                     EVKRLLDEAVKLIE"
     CDS             10001..11044
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2372"
                     /sec_met_domain="PF04055 (E-value: 3.5e-23, bitscore: 80.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.2e-09, bitscore: 33.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.4e-13, bitscore:
                     46.8, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.3e-09, bitscore: 35.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRILRAPELVSWEITNQCNLRCNYCSNDDNFYASSLSLSIEDCK
                     KVIDILHKTEVFRINIEGGEPFLRNDLLEIIGYLNEKGYIPKITTNGTLITRELAKELA
                     NYKILTLQISLDAPNKECYSNIRGSETYFDRILESIEYLKEFKIPICLSMVLLKTNINL
                     VEDFIIFAKKIKVNGVRFIDFIPNSNEKMLLVPSNEEIKKAYITMNKFENTPEFKIIKP
                     YKLLSTLVFDKKNEINYSNFTLLQWVNREKKVICEAANIIVHIKANGDITPCVFFREKK
                     FIAGNILQNDFLSIWNHSPIFNLFRELSNNNCPPCIHFSTCMGGCRALAYYVNKNLNGI
                     DSRCWHN"
     PFAM_domain     10040..10474
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2372_0065"
                     /evalue="1.40E-22"
                     /label="ctg1_2372"
                     /locus_tag="ctg1_2372"
                     /protein_end="158"
                     /protein_start="13"
                     /score="80.9"
                     /tool="antismash"
                     /translation="EITNQCNLRCNYCSNDDNFYASSLSLSIEDCKKVIDILHKTEVFR
                     INIEGGEPFLRNDLLEIIGYLNEKGYIPKITTNGTLITRELAKELANYKILTLQISLDA
                     PNKECYSNIRGSETYFDRILESIEYLKEFKIPICLSMVLLK"
     PFAM_domain     10766..10948
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2372_0066"
                     /evalue="8.70E-09"
                     /label="ctg1_2372"
                     /locus_tag="ctg1_2372"
                     /protein_end="316"
                     /protein_start="255"
                     /score="35.8"
                     /tool="antismash"
                     /translation="CEAANIIVHIKANGDITPCVFFREKKFIAGNILQNDFLSIWNHSP
                     IFNLFRELSNNNCPPC"
     aSDomain        10766..11017
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2372_0027"
                     /evalue="6.90E-13"
                     /identifier="TIGR04085"
                     /label="ctg1_2372"
                     /locus_tag="ctg1_2372"
                     /protein_end="339"
                     /protein_start="255"
                     /score="46.8"
                     /tool="antismash"
                     /translation="CEAANIIVHIKANGDITPCVFFREKKFIAGNILQNDFLSIWNHSP
                     IFNLFRELSNNNCPPCIHFSTCMGGCRALAYYVNKNLNG"
     CDS             11068..11340
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2373"
                     /sec_met_domain="PF05402 (E-value: 1.9e-15, bitscore: 54.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.2e-08,
                     bitscore: 32.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKKNEFINVRQETEEEYIFFNTKTGETFLLNDIGYIIFECALKS
                     MSMSDLVKNVCQKTNDDIEVANKTIENFIKILLEKNILIQGDTKE"
     PFAM_domain     11116..11316
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2373_0067"
                     /evalue="2.60E-06"
                     /label="ctg1_2373"
                     /locus_tag="ctg1_2373"
                     /protein_end="83"
                     /protein_start="16"
                     /score="27.7"
                     /tool="antismash"
                     /translation="EYIFFNTKTGETFLLNDIGYIIFECALKSMSMSDLVKNVCQKTND
                     DIEVANKTIENFIKILLEKNIL"
     CDS             11337..12494
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 238.4; E-value: 2.2e-72)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2374"
                     /transl_table=11
                     /translation="MKNNRNAINLLCSQFISEIGNWIDRVALLTLVYNVSKSSLQMSIL
                     SILILSPAIIFGIPFGKIIDLSNKKTILVFGDISRALLVILVPYFTNYVFLIVFIISSV
                     TAIYENTRNSIIPELTTKEEIRKINSLSSSLNSIMMVIGPSIGGLLTSYLNLKYCFFID
                     SFTFLVSAIFVSQISYHKYESTENKSRNIRYLEFLKYLKSNFIIKSLIILNGLIGLFAG
                     ILNGLLIVYVINYLHTDSKGYGFILTSKGTAMVITSLYVYKYIKTIKNETLLLTGVIGI
                     GISTTLFSLSNIFVFALFIHFVNGICNSFYAIARTTIIQENCNKKLLGRVFSFNSIVGN
                     ISSIISLLIGGIISNTISVKTIFLTSGISIALIGMVYFINLKKLS"
     PFAM_domain     11373..12467
                     /aSDomain="MFS_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05977.15"
                     /description="Transmembrane secretion effector"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2374_0068"
                     /evalue="2.60E-22"
                     /label="ctg1_2374"
                     /locus_tag="ctg1_2374"
                     /protein_end="377"
                     /protein_start="12"
                     /score="79.0"
                     /tool="antismash"
                     /translation="SQFISEIGNWIDRVALLTLVYNVSKSSLQMSILSILILSPAIIFG
                     IPFGKIIDLSNKKTILVFGDISRALLVILVPYFTNYVFLIVFIISSVTAIYENTRNSII
                     PELTTKEEIRKINSLSSSLNSIMMVIGPSIGGLLTSYLNLKYCFFIDSFTFLVSAIFVS
                     QISYHKYESTENKSRNIRYLEFLKYLKSNFIIKSLIILNGLIGLFAGILNGLLIVYVIN
                     YLHTDSKGYGFILTSKGTAMVITSLYVYKYIKTIKNETLLLTGVIGIGISTTLFSLSNI
                     FVFALFIHFVNGICNSFYAIARTTIIQENCNKKLLGRVFSFNSIVGNISSIISLLIGGI
                     ISNTISVKTIFLTSGISIALIGMVY"
     CDS             complement(12581..14008)
                     /locus_tag="ctg1_2375"
                     /transl_table=11
                     /translation="MSEKSYGQELYEKLSYTSKNAWEVLKEEEKPFVFDLAEKYKHFLN
                     CAKTEREAVEYFIERAKEKGYKEFNSNIQKLKPGDKVYFVNNNKSILLAHIGKKPLKEG
                     FNLIGSHIDSPRLDLKPKPLYESNELALLKTHYYGGIKKYHWVNVPLSIHGVVVKSDGS
                     KVKITIGEDENDPVFYITDLLVHLSSDQLQKKASEAIPAENLNVLIGSMPFNDEKVKEK
                     VKLNVLKILNEKYGITEEDLISADIEVVPAAKARDVGLDRSLIGAYGQDDRACSFLAAE
                     GIFSIDETPEKTALVYLVDKEEIGSVGISSAEASFFDVSVAKLMKALGEYENSLDLALC
                     FENSAAISGDVAAALDPTYEGAYDKLNSTLIGHGVTIEKYTGVRGKYSGSEATAEYVGK
                     IRNFLNSNNICWQTGLLGKVDQGGGGTIALFIARKMINVIDSGVPVLSMHSTFEITSKV
                     DVYMTYKFYNQFLRKFE"
     PFAM_domain     complement(12599..13882)
                     /aSDomain="Peptidase_M18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02127.17"
                     /description="Aminopeptidase I zinc metalloprotease (M18)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2375_0069"
                     /evalue="8.40E-91"
                     /label="ctg1_2375"
                     /locus_tag="ctg1_2375"
                     /protein_end="470"
                     /protein_start="42"
                     /score="305.0"
                     /tool="antismash"
                     /translation="FLNCAKTEREAVEYFIERAKEKGYKEFNSNIQKLKPGDKVYFVNN
                     NKSILLAHIGKKPLKEGFNLIGSHIDSPRLDLKPKPLYESNELALLKTHYYGGIKKYHW
                     VNVPLSIHGVVVKSDGSKVKITIGEDENDPVFYITDLLVHLSSDQLQKKASEAIPAENL
                     NVLIGSMPFNDEKVKEKVKLNVLKILNEKYGITEEDLISADIEVVPAAKARDVGLDRSL
                     IGAYGQDDRACSFLAAEGIFSIDETPEKTALVYLVDKEEIGSVGISSAEASFFDVSVAK
                     LMKALGEYENSLDLALCFENSAAISGDVAAALDPTYEGAYDKLNSTLIGHGVTIEKYTG
                     VRGKYSGSEATAEYVGKIRNFLNSNNICWQTGLLGKVDQGGGGTIALFIARKMINVIDS
                     GVPVLSMHSTFEITSKVDVYMTYKFYNQF"
     CDS             14224..15438
                     /locus_tag="ctg1_2376"
                     /transl_table=11
                     /translation="MQNAREILKYIGPGLLVTVGFIDPGNWASNVAAGSQFGLKLLWVV
                     LLSTIILIVLQHNAAHLGIATGLCLAEATSIYLNKSLAIVVLSSAMLATVSTAMAEILG
                     ASIALEMLFKIPIKLGCLIILPFTMFFLFSNSYKKVERWIIAFVSLIGLSFLIELFLVK
                     VPVKDVVIGWITPSIPSGSLIVVLSILGAVVMPHNLFLHSEIIQSRQWNTQDEKVIKHQ
                     LKFEFVDTLFSMFIGFLINSSMIIIAHTTFYTKGIFVESLPQAQQMLKPILGNFSATIF
                     AFALLLSGISSSITAAYTGGTIMAGFYRRPYNIEELPTKVGIIIPLVLASIIIVFISNP
                     FRALILSQMLLSIQLPITIILQIYLTSSKKVMGKFANSLADKIILGIVAALVIGLDVFL
                     LITTL"
     PFAM_domain     14302..15357
                     /aSDomain="Nramp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01566.20"
                     /description="Natural resistance-associated macrophage
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2376_0070"
                     /evalue="1.50E-109"
                     /label="ctg1_2376"
                     /locus_tag="ctg1_2376"
                     /protein_end="378"
                     /protein_start="26"
                     /score="366.4"
                     /tool="antismash"
                     /translation="WASNVAAGSQFGLKLLWVVLLSTIILIVLQHNAAHLGIATGLCLA
                     EATSIYLNKSLAIVVLSSAMLATVSTAMAEILGASIALEMLFKIPIKLGCLIILPFTMF
                     FLFSNSYKKVERWIIAFVSLIGLSFLIELFLVKVPVKDVVIGWITPSIPSGSLIVVLSI
                     LGAVVMPHNLFLHSEIIQSRQWNTQDEKVIKHQLKFEFVDTLFSMFIGFLINSSMIIIA
                     HTTFYTKGIFVESLPQAQQMLKPILGNFSATIFAFALLLSGISSSITAAYTGGTIMAGF
                     YRRPYNIEELPTKVGIIIPLVLASIIIVFISNPFRALILSQMLLSIQLPITIILQIYLT
                     SSKKVMGKFANS"
     CDS             complement(15496..15696)
                     /locus_tag="ctg1_2377"
                     /transl_table=11
                     /translation="MECTLSKNLSICTCTYEPCPRKGRCCECLHYHRKNGQLPACYFSK
                     EAERTYDRSIENFIRDYSSRK"
     PFAM_domain     complement(15508..15678)
                     /aSDomain="DUF6485"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF20095.1"
                     /description="Domain of unknown function (DUF6485)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2377_0071"
                     /evalue="2.60E-10"
                     /label="ctg1_2377"
                     /locus_tag="ctg1_2377"
                     /protein_end="63"
                     /protein_start="6"
                     /score="40.6"
                     /tool="antismash"
                     /translation="KNLSICTCTYEPCPRKGRCCECLHYHRKNGQLPACYFSKEAERTY
                     DRSIENFIRDYS"
     CDS             complement(15717..17327)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 125.6; E-value: 3.7e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2378"
                     /sec_met_domain="PF04055 (E-value: 5.8e-17, bitscore: 60.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILLVAINSKYVHTNLAVRYLYQLCKENYPCEYVEFNINQSLHDV
                     LYEILSKKPEYVAISTYIWNRSYVEKLVEGLKKARKDIKIILGGPEVYFDSLDEWKFVD
                     IIIRGEGEYPFLDLCDHIAAGRQYTQKEYPPFDLNKLPFAYKDEKLDQSRIYYYESSRG
                     CPFRCTYCLSSIEKSVRFASLEKVFEELDYLFKKQVRLIKFVDRTFNANKERAIKIIEF
                     CKQKSQATQIHFEIDPTLLDSDIITAINTSKDNLFRLEIGLQSFNPQTLDAIDRFYDID
                     KIDKNLKELMENKKAIVHLDLIAGLPYEDFLSFKRSLDKTILYFADEVQLGFLKMLKGT
                     KIREEAAKYNYEFFKDPPYEVISNSFISFEEIYELKKIEDLIDKVYNRQYLYFTLRYIF
                     QKISPSEFFEKLSSKVNSNLNTREFIKELYIAIKENFDFDKAVFDNLFRFDILRRFPEE
                     FLPEELAVSKEEKEKIKQAIYRVSPEYQDIGEPKEIIRRSRACIFGFDIERFIEDNKIE
                     NGDFLYIFFEEKVKKIKLQ"
     PFAM_domain     complement(15807..16286)
                     /aSDomain="DUF4080"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13311.8"
                     /description="Protein of unknown function (DUF4080)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2378_0074"
                     /evalue="6.60E-17"
                     /label="ctg1_2378"
                     /locus_tag="ctg1_2378"
                     /protein_end="507"
                     /protein_start="347"
                     /score="62.4"
                     /tool="antismash"
                     /translation="KYNYEFFKDPPYEVISNSFISFEEIYELKKIEDLIDKVYNRQYLY
                     FTLRYIFQKISPSEFFEKLSSKVNSNLNTREFIKELYIAIKENFDFDKAVFDNLFRFDI
                     LRRFPEEFLPEELAVSKEEKEKIKQAIYRVSPEYQDIGEPKEIIRRSRACIFGFDI"
     PFAM_domain     complement(16398..16853)
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2378_0073"
                     /evalue="8.20E-16"
                     /label="ctg1_2378"
                     /locus_tag="ctg1_2378"
                     /protein_end="310"
                     /protein_start="158"
                     /score="58.9"
                     /tool="antismash"
                     /translation="ESSRGCPFRCTYCLSSIEKSVRFASLEKVFEELDYLFKKQVRLIK
                     FVDRTFNANKERAIKIIEFCKQKSQATQIHFEIDPTLLDSDIITAINTSKDNLFRLEIG
                     LQSFNPQTLDAIDRFYDIDKIDKNLKELMENKKAIVHLDLIAGLPYED"
     PFAM_domain     complement(16977..17315)
                     /aSDomain="B12-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02310.21"
                     /description="B12 binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2378_0072"
                     /evalue="4.60E-13"
                     /label="ctg1_2378"
                     /locus_tag="ctg1_2378"
                     /protein_end="117"
                     /protein_start="4"
                     /score="49.4"
                     /tool="antismash"
                     /translation="VAINSKYVHTNLAVRYLYQLCKENYPCEYVEFNINQSLHDVLYEI
                     LSKKPEYVAISTYIWNRSYVEKLVEGLKKARKDIKIILGGPEVYFDSLDEWKFVDIIIR
                     GEGEYPFLD"
     CDS             complement(17455..17931)
                     /locus_tag="ctg1_2379"
                     /transl_table=11
                     /translation="MREDKKTIIVFSNDMDKVMAAFVIATGAAAMGDEVTMFFTFWGLN
                     VLRDAKKKAQGKSFLEKMFGAMMPKGVEKLPLSKMNFLGIGPKLMKYMMKKKNVMMLPE
                     MIKQAQELGIKMVACSMSMDVMGIKKEELIDGVEIGGVATYLGEASEAGVNLFI"
     PFAM_domain     complement(17461..17922)
                     /aSDomain="DrsE_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13686.8"
                     /description="DsrE/DsrF/DrsH-like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2379_0075"
                     /evalue="3.30E-59"
                     /label="ctg1_2379"
                     /locus_tag="ctg1_2379"
                     /protein_end="157"
                     /protein_start="3"
                     /score="199.3"
                     /tool="antismash"
                     /translation="DKKTIIVFSNDMDKVMAAFVIATGAAAMGDEVTMFFTFWGLNVLR
                     DAKKKAQGKSFLEKMFGAMMPKGVEKLPLSKMNFLGIGPKLMKYMMKKKNVMMLPEMIK
                     QAQELGIKMVACSMSMDVMGIKKEELIDGVEIGGVATYLGEASEAGVNLF"
     CDS             complement(17944..18168)
                     /locus_tag="ctg1_2380"
                     /transl_table=11
                     /translation="VAEYFIDAKGLQCPGPITQLFKQMKEAQSGDIVTIEVTDPAFKRD
                     VESWCKKTKNELLSLEEVNDVIKAKIKKA"
     PFAM_domain     complement(17950..18153)
                     /aSDomain="TusA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01206.19"
                     /description="Sulfurtransferase TusA"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2380_0076"
                     /evalue="2.60E-19"
                     /label="ctg1_2380"
                     /locus_tag="ctg1_2380"
                     /protein_end="73"
                     /protein_start="5"
                     /score="69.0"
                     /tool="antismash"
                     /translation="IDAKGLQCPGPITQLFKQMKEAQSGDIVTIEVTDPAFKRDVESWC
                     KKTKNELLSLEEVNDVIKAKIKK"
     CDS             complement(18363..18620)
                     /locus_tag="ctg1_2381"
                     /transl_table=11
                     /translation="MPDKERKEEILSRLKNIKGHIDGIIKMVEEEKECEEIMLQIAAVK
                     NAIEKVGYFIIESHAAECLSSVGNKDDIQRILNIMMKFLG"
     PFAM_domain     complement(18381..18602)
                     /aSDomain="Trns_repr_metal"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02583.19"
                     /description="Metal-sensitive transcriptional repressor"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2381_0077"
                     /evalue="5.50E-22"
                     /label="ctg1_2381"
                     /locus_tag="ctg1_2381"
                     /protein_end="80"
                     /protein_start="6"
                     /score="78.0"
                     /tool="antismash"
                     /translation="KEEILSRLKNIKGHIDGIIKMVEEEKECEEIMLQIAAVKNAIEKV
                     GYFIIESHAAECLSSVGNKDDIQRILNIM"
     CDS             complement(18630..18833)
                     /locus_tag="ctg1_2382"
                     /transl_table=11
                     /translation="MKKAVLNKNLCDRSPFCPASRSCKFGAIKRKVRGFFDVEIEIDKE
                     KCTGCGGCTRYCPQGAIEIVEE"
     PFAM_domain     complement(18645..18716)
                     /aSDomain="Fer4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00037.29"
                     /description="4Fe-4S binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2382_0078"
                     /evalue="5.40E-09"
                     /label="ctg1_2382"
                     /locus_tag="ctg1_2382"
                     /protein_end="63"
                     /protein_start="39"
                     /score="35.6"
                     /tool="antismash"
                     /translation="IEIDKEKCTGCGGCTRYCPQGAIE"
     CDS             19055..20167
                     /locus_tag="ctg1_2383"
                     /transl_table=11
                     /translation="MKKLCKMYLVFFIVFLLIFNVAFAQSIKVTPKVINGKMYVDLDSL
                     KDFFGFDYVKSQDGVTIQKKDLSISEVIDKVNKSVVAIIGDSKKIKADDFYYSKIPAGL
                     THGSGVVIDKNGLILTNNHVVEDMKQPYVIFYDAKAYKATVLYRNKDIDLALLKVNRTN
                     INPIEIEDPKNIKVGQEVLAIGTPLFLGWQNSVTKGIISGLNRPVDETYTFLQTDAAIN
                     PGNSGGPLVNMQGKLVGINTLGIEYFQGINFAIPAENILYFLNHYKKFGKIKRCYLGLE
                     FEDSWLSIVGLPSTLGLKIIDVKEDSPLKGFIQENDILVSIDNYPVNSIAEYNQTLMKY
                     LPGDKVKINIKRNGKVIEKEVVLKEYPENK"
     PFAM_domain     19373..19774
                     /aSDomain="Trypsin_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13365.8"
                     /description="Trypsin-like peptidase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2383_0079"
                     /evalue="2.60E-34"
                     /label="ctg1_2383"
                     /locus_tag="ctg1_2383"
                     /protein_end="240"
                     /protein_start="106"
                     /score="119.5"
                     /tool="antismash"
                     /translation="GSGVVIDKNGLILTNNHVVEDMKQPYVIFYDAKAYKATVLYRNKD
                     IDLALLKVNRTNINPIEIEDPKNIKVGQEVLAIGTPLFLGWQNSVTKGIISGLNRPVDE
                     TYTFLQTDAAINPGNSGGPLVNMQGKLVGI"
     PFAM_domain     19883..20137
                     /aSDomain="PDZ_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13180.8"
                     /description="PDZ domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2383_0080"
                     /evalue="1.10E-11"
                     /label="ctg1_2383"
                     /locus_tag="ctg1_2383"
                     /protein_end="361"
                     /protein_start="276"
                     /score="45.0"
                     /tool="antismash"
                     /translation="YLGLEFEDSWLSIVGLPSTLGLKIIDVKEDSPLKGFIQENDILVS
                     IDNYPVNSIAEYNQTLMKYLPGDKVKINIKRNGKVIEKEV"
ORIGIN
        1 atatctgcat caggacctga cataacagta tccccaactt ttaagccctc aggtgctaag
       61 atatatcttc tttcaccatc tgcataacat aagagtgcca aaaatgctgt tctgtttggg
      121 tcgtactcga tagcctcaac ctttgcagga ataccatcct tatccctttt aaagtcaaca
      181 attcttatct ttttcttatg tccgcctcct ctatgacgaa cagtaattct tccttgattg
      241 tttcttcctg cccatttctt ctctgtaaat actaaggatt tttcaggctc tgtcttcgta
      301 atgatctctt tatagttcaa aactgatgca tttctgcggc ctggcgatgt aggcttgtaa
      361 actattatac ccaccttttt tcccctcctt attagcattt atgctcaatt aaattaagct
      421 gtcaaaaaac tctattgtct tgctcttgtc tgtaagttta acaatggcct ttttccatgc
      481 ctttgttctt ccttcaaatc ttcctactct ctttctcttt ggttttacgt tcattgtcca
      541 aaccttttca acctcaacgc caaacagctg ctcaacagct ttctttatct caattttgtt
      601 agctcttcta tcaacttcaa atgtgtattt tttctgtgga atcatgctca tgctcttttc
      661 tgttattatt ggccttttaa ttatctcttc tggcaacata ttatgcgtac acctcctcta
      721 ctttctttac agcgtcctgg aggataataa acttgtcata ttttagtata tcaaacacat
      781 tcaagtttcc tacttgcaat gtctttactt ccggaatgtt ctttgttgac ttttgtaaat
      841 attcattctt ttcaggaatt actatcaagg ctttttcatt ctcaagccct aaattcttta
      901 aaaccctgat tacctctttt gttctatact ggttcatatc ccacttgtca agcacaatga
      961 gattgttctc tttgactttg gaagacagtg cacattttaa agcaagtctt cttactttct
     1021 ttggaaggtc tattgaaaaa tctcttggtt tttttgcaaa tacaacgcca ccttttctcc
     1081 atgtgggagc tctgatagaa ccctgtcttg ccctacctgt tcctttctgt ctccatggtt
     1141 ttctaccacc accacggact tctgctcttg tctttgcagc aaatgtcccc tgacgcctgt
     1201 ttgcaagatg tgcaacaaca gcttggtgca aaacatgagt atttatagga acattgaaga
     1261 ttgagtcatt aagctcaatc tcaccaattt gttgcccttc tatattgtaa accggaacct
     1321 ttggcattct ttttcctcct tcctaaaact tagagcttat ttgctcttaa ctgagtctcg
     1381 gattattaaa agtgaattct tatttcctgg aacacttccc tttacaagaa gcaggtttct
     1441 ttctgggtca acctttacaa cctgtaagtt caaaactgtc actctctgac cacccattct
     1501 accaggcatc tttttacctg ggaatgttct tgcagggaat gtattagaac ccattgaacc
     1561 aactcttctg tgatacatag aaccgtgact cataggacct ctttgctgac catgtctttt
     1621 gataacacct tggaatcctt tagcttttga aataccagtt acatctactc tttcgccagg
     1681 tgaaaagatg tcaaccctta tctcttgccc aacttcatat ttatctgcat cttttagcct
     1741 caattctctc aaatatctct ttggctttac accgtgtttt gcaaaatgac ctcttaaagg
     1801 cttgtttagt ttggtttctt ttatatcctc aaaacccact tgaatagctg cataaccatc
     1861 tttttcaact gtcttttttt gaacaacaac acatggccct gcttcaatta ctgtgacagg
     1921 tactaccttc cctgcctcat caaaaacctg tgtcatacct atctttttgc caagtatacc
     1981 ctttgtcatg tgtgcttaca cctcctttag cttaatctcg atgtcaacac cagcaggaag
     2041 ttcaactctc ataagtgcat cgactgtttt ctgtgtgggc ttgataatgt caataagtct
     2101 tttgtgagtt ttgatttcaa attgctcacg cgaatcttta tacttgtgtg gtgccctgat
     2161 aattgtaatt acctctctgt ctgttggcag tggtactggt cctgatacct ctgcacctgt
     2221 actctttgct gtctcaacaa tcttccttgc tgactgatct aaaagcttgt aatcaaacga
     2281 ttttaacttg attcgcattc tttgtgcctt tgacatgtat tcccctcctt aaaaatagtg
     2341 ttatttattt tatctgcgac aggggaactt ggcaacttag ccgtgtgtgt cagaactttt
     2401 tatataaaaa tacccggagt tttccatctt cgggcataaa aacaccgggc atgaaatatt
     2461 ctttcatacc ttccccgtgt cgcccgtctc aaaggacaag acatactcag caaaaattcc
     2521 ctgcaaagtc ctttaccttt gcagcaacct tttgcctcat cgccagtttt tttaaatgtt
     2581 ttttctttta cccacacaac gactttataa ttttataata aaaaaaggcg gtttgcaaga
     2641 gaaattttaa taagttgctc gaataggtgt agagatattt accacagcga aagaatgtac
     2701 gaagaagaaa atttcataaa aagagttgag gctgcctccc tcctgtttga tataattaaa
     2761 aagtgtaatc taatattcaa aagaaaaata gaaaaactac caggatggga ggacagccta
     2821 ctatgaatat tatatcatac cacgaactaa gaaaaatatc ccctcaaaaa gctagagaat
     2881 tagttcgaaa agtctttgaa tcaaataaca aaaacgtatc aaaaactgct aaaatattag
     2941 gtgtatcaag acataccgta agaagagctg tctacggtcc tcttgaagat aaatcaaaaa
     3001 aacctaaatc ttctcccaaa aagctttctt ctgaactcga aaattttatt gtcgaagagt
     3061 ctaaaaaaac tggttttaga tatagacgtt tgtcttttta tcttctcaga aaatatggta
     3121 tcaaaataag tgaaaacaca ataaagtcaa ttcttagaag aaactctgta gctcgaaaaa
     3181 caaaaagaac aaaaaaaggt gaaagaagtc tatacgatta tgaaactctt atcccatttt
     3241 ctgaatttca gcttgataca aaacatcttt tagacaaaga aagtcttccc aaggaggtat
     3301 atgaacatat gaaaagatac aatttgcctt gctatgagtg gaacataata gatgttgcaa
     3361 caagaacaag atttacagcc tattcttacg aactttcatc cgcttttgga tttatgttca
     3421 tatccttagt tgcattatgg ttaagaactc ataatgtaag aaatataata aagatccgat
     3481 tagacaatgg agcagaattt tgtggaggaa gcgaaagaaa gttaaagcag tggaatgaga
     3541 tgctgtcatt tttgggtgta gaactaaatc ctattccacc aaaagcaaag catttaatgg
     3601 gtataattga aaattcacat agagctgatg atgagtattt tttaatgatt catgctgaaa
     3661 gatgtaaaac aaaagatgaa tttattcaaa gagcccagaa atggcaagat acatggaact
     3721 ttttcagacc tcataatggt aaaggaatga acgggaggac accattcgaa aaattcatag
     3781 cttcaaaatc tctggtctcc tcccatatat ttcaatttcc tacattactt cttgaggata
     3841 ttatgaaaaa agtaggcacc ttctattctc tgttctgtaa taaatttggt ggtaaatatg
     3901 tcttcaccac gtaccaattt taataagttg ctccgccttc ttgatagatt tttttaatta
     3961 gctcaacgtc aacctcatcc gcctttacaa agtgatttgg ctcagcacca caatatggac
     4021 acggggaatt taaatctaca atttcataac cacaaattcc acagacatat ttttcttgca
     4081 tattcatttt acctcctcag tatattttac ttctctcgtt atttatttaa tacccacaaa
     4141 tcaaaatttt ctatcaagat aatcttttaa caatttgata tgtttctctt cgtcaagtat
     4201 tattctttct aaaagctttc tgatgtacct atcatctatc atttcaatgt gcctcttgta
     4261 atttttgatt gcctcctttt cggattgtat atcaattttt atcatgtctt ttaaatcttt
     4321 gtcgtagttt acaaaatacc cgttccagta ctgaccatat gttgtgtaag aacccctata
     4381 ttttggcagg gcaccaagta ggtaaattgt agtaccaaga aggtccaagt gtttcatctc
     4441 aacccgagca attccaataa tcagctctgc aaagtctttg tttcttacat cgcttatgaa
     4501 atgctggtaa gaatagagtg cgattgctgt aaactcactt gcatatcctg catagtcatc
     4561 aagcaaaatt tctgcatagt gtctgtttgg ctcttcaact tttggctctg gatatggtgc
     4621 atcatatgca aacttagtcc aatccatttt taacctatta cctcccaaaa gtttttattg
     4681 ggcttttaat acattatatt tttgaaagca atttttgcta cttttcaggc ttcattttga
     4741 aaaacttcct aaaaggacgg ataatttatc aaaaaacttt ggtaaaactt ttcgaggttt
     4801 tgatgtataa ttagcttaaa gtaaagaagt ttcaaagtag tttaaggtgg tggaaaagat
     4861 ttatgaaaat aggtgtggga aatcttctct tatcaatctc atacttaata gacattgccc
     4921 aaggcagaaa ggaacatgca ccaaaggtca cttacatatc tttgcaaatt gcaaaacagt
     4981 tacaaatcga aaaaaacgag acaaaaaaga tctattatgc atcatttctg catgatattg
     5041 gtatcactgt gtcggataat aatttttatg cttcacatgt ggatattcaa ctcgcaaaaa
     5101 accattgctt gttaggatat gagtttgtta gaaagctccc attagatgaa gagatttcag
     5161 aaatcattaa ataccatcat gacttttaca acggctcagg tgcattcgga tacgactata
     5221 gagttttgcc attggcctct cagattataa atttagctga ccagatagat ataagcatga
     5281 actggtcaaa tccttactat ctacaggttg atgatttaaa agagtgggtt aagaaaaata
     5341 agggcatttt gtttaatcca ttcatagttg atgcattttt agatattgct gataaggata
     5401 aattttggtt agacctttac aaccctcaac tgaggcagat tatcttagag cttttaccag
     5461 atgaagaagt ttactttgat ataaaaacta tgctcaaatt ctccgaagca gttgctctct
     5521 tgattgacaa taaaagcaag tttacacatc ttcactccca ggggttgtca gaggtagtat
     5581 ttgaaattgc caaaataatg ggattagatc atgaaacttc taataaattg aaaattgctg
     5641 gctatttaca tgatttgggt aagatggttg tgccaaatga gatactaaat aaagtgggaa
     5701 agcttacaaa agaggaattt tatataataa agtcacatcc gtactacaca aagctaattt
     5761 tggaccaaat ccctgtattc aaaggcgaaa tctctaactg ggcaggaaat catcacgaaa
     5821 ggatagatag aagtggatac cctgaaaaac ttggaaagga cgaactttct cttttagata
     5881 gagtagtggg aatatgcgat gtataccaag cccttattga agatagacca taccgaaaag
     5941 gattgggtca aaaagaagca ctaagtataa tttatgatat ggtgaagaat gaactatttt
     6001 tagaagaaga gtttgaactt ctcagaagag cagtagtatg aaagaagatt ttactactgc
     6061 tctttgtagc tactgccttt gataacaaat cttgcaccaa ctggttcagc attttcagct
     6121 tttactgcaa agccatgctt gtcaaatatt gctttagcaa tggaaagtcc taagccactt
     6181 tctccccttt tccctttaaa aaatctttca aaaattttgt caatttcatc atttttaaaa
     6241 cccactccgt catcttctac tctaacttca aattcgtcct tttgaagttt gatttcaacc
     6301 acaactttac ttttagcata tcttatacag ttagaaatta tattggaaaa agcttctttt
     6361 agtttttctc tatcacacaa aactggaatt ttggtattag gctcaaatac tattttaatt
     6421 ccctttgaaa gagcataccc ttcattgtct aaaactgcat caaaaaggat atcttccaga
     6481 ttgctctttt caaatacaaa atagttctca acagactcaa tcttagtaag gtctataatc
     6541 tggtttatca atatctttag cttatctaca tgctcaatta tcctgttggc tgcgtgattg
     6601 gctttctcta catctaaaag tcccattttc aatacttctg catacccccg aatagaagta
     6661 agcggtgttt tcaattcatg agagatgttt tgcagaaatc taatctgtgc ttggttatac
     6721 tctgaaatct tttctataag cttgttaaac tcatgtgcaa tcataccaac ttcatctctt
     6781 gaacctacct caaccttttt attaaacctc atctttgaag cttctattat tccttctttt
     6841 aacttcagaa gaccctgaat tatttgctta gatacaaaca cactaactgc agctgccaag
     6901 agcgcagtaa agattgcaat ctggaaaatg agactaaaaa acctcttttg aaaaattgaa
     6961 attctttcta agtcactgat aataaggata aagaaatgtg tatttgattt acttttatac
     7021 aaagtaaaca aataaggttt ctcctgtaat tgcccaattt caaaactata tgaaaactcc
     7081 ttattctcat taaataactt cattattttt actcgcgctt caacatccag ctctttattt
     7141 gaatactcaa ttgagccatc attagtaact attacaatat agtcctgaag aaatttatat
     7201 ccccatgttt caaaatatga ctcaaatttt tttagttctt taatattttt actttgattt
     7261 ataaaaaagg attcgacaag ctttgcaaat cttaaattat ctgtttttac ctgttctatt
     7321 aagttacttt taaaagtagc ataaaaaatt atcgaaaatg tagcaaatat gaacactatg
     7381 agacccaagt atgatagata gattttagtt ctgattttca tctttcttct cctcgagttt
     7441 atatccaagt ccccacattg tctttatctc gatgggaagt ttatactgta aaatcttttt
     7501 tctcaacctt tttatcacat catctaccat tctttcatca tataaagccg ggtctcccca
     7561 tacctgctct aatatgtagc ttcttttgtg taccttggag tgctccctaa agagaagtaa
     7621 aaatgtctca aattcttttg gcgaaaggtc cacttttaca ttattgtaaa atacactctt
     7681 ctgatttaaa tcaaccttta ttccaaaaaa ttctaaggca ttgtcaacct taagagtatc
     7741 tttacctact cttcgtaaaa ttttcttaat tcttgcttca agctcaagta gtgagaacgg
     7801 ttttgatatg taatcatcac tgccaagctc aagtcccaaa actttatcaa actcttcacc
     7861 tttagccgag agcattataa ttggtacatt gctacttttc cttatttttt tgcacagctc
     7921 atatccatca atgtctggga gcataatatc taatatgact atgtcaggct cattttcctc
     7981 aaactctttt agaaaactcg aagcatcttc aaatgtttta acctcgtaac ctctgcttat
     8041 cagatactga tagataatgt ccaaaatatc tttttcatca tcgacaacat atacaaggta
     8101 tcttgacatt gtgattttcc tctctttatt tgaataattc aaaaaatatc ttgtcttgtt
     8161 tgaaaaattc ttgaaacttt tgtatactat ataattgtca ggatttataa gactatttct
     8221 aagattcatt atagcacatt ttatgcactg tttgcaggag gtgaaacaag atgataaagt
     8281 ttggaacaga cggctggaga gcagtaatca gtaaggatta cacttttgac aatgtaaaga
     8341 ttgtcgccca agcaattgct gactatataa aagaaattga tgacaaaaga cctgttttgg
     8401 taggatatga cacaagattt atgtcagaag agtatgctcg gctttgcgca ggggttcttg
     8461 ttgcaaacgg cacaaagaca tatcttacaa aaaagccaac accaacacct gttgtatcat
     8521 ttactgtcaa gaacatgaat ttagcaggag ctataatgat tacagcaagc cataacccac
     8581 cacaatggaa tgggataaag ttcaaaggcg attatggtgg gtctgcacta ccgtctataa
     8641 ttgctgaaat tgaaaaacat ctttataaaa atgaggtaaa gtttgttgaa cctgaagaaa
     8701 gcagtctctt ttcctttata gatgctgaca aggactattt tgaacacatt gaaaagcttg
     8761 tagaccttaa tcttattgca aaattcaaac cttttgcaat aatcgatcca atgcacggtg
     8821 ctggagttgg atatgttaaa accttgttag aaaaatatgg aatcaaacac atccagataa
     8881 gagatgaaag aaacccgtac tttggaggag tcaatccaga acctatttat aaaaaccttg
     8941 gaaaattgat tgatactgtt gtccaaaaca acgcagacat tggccttgca acagacggcg
     9001 atgcagatag agttggcgct gttgatgaaa aaggagagtt tattgattca cacagaatat
     9061 atgcactgct tctgagacat ttagttgaag caaaaggttt aaagggtggt gttgtaaaaa
     9121 cattttcaac taccaatatg gttcctattt tggcaaacaa gtacggactc aaaatctatg
     9181 aaacaccgat tggctttaaa tatatctgcg aacttttctt aaaagaagac attctcattg
     9241 gtggcgagga aagcggaggt attggaatta aaaatcatat acctgaaaga gatggaattt
     9301 tatgtagctt gctgctcctt gagattatgg cttattatca aaaaccaatc agtcaaatac
     9361 ttgacgagct ttttaaagaa ataggttatc actactatga cagagttgac ctgcatttgc
     9421 caatcgaaat caaagaaaag acgttgaaga tgatttccca aaacacagag tttgcaggca
     9481 gaaagattaa agagattcaa acattagacg gctataaata tatctttgaa gatggctcat
     9541 ggatactctt cagagcatct ggcacagaac ctgttttgag agtatacaca gaacagttca
     9601 ccaaagacga ggtcaaaagg cttttagatg aggctgtgaa gttgatagag gagatgaaat
     9661 aaaaaggatt taataattgg tctattagct ctagatatgc agcacaataa atacatctat
     9721 aatttatgca ttttgtatat tgcttttttt tttttttttt ttttttttta caattattat
     9781 gtaaaactat tgaactgctg aatattaaag cttaaagtct atatcaaaag gaaggagggg
     9841 agtttgatga aaaaacaacc tattattgta gagatgtttg caggttgtga tagtatacat
     9901 taaaattctg tatattcttc tcaggaggtt cgcaccttta acgaacctcc ttcttcacaa
     9961 aaaatcaaca attattgcaa attgaggaag tgaaaataca atgaacagaa ttttaagagc
    10021 tccagaactt gtaagttggg aaataacaaa tcaatgcaat ttaagatgca attattgttc
    10081 aaatgatgat aatttttatg cttcatccct atctctttct attgaggatt gcaaaaaagt
    10141 tatagatatt ctacataaaa ccgaagtctt tagaataaac attgaaggcg gagaaccttt
    10201 tttgagaaat gatttgttag aaataatagg atatttaaat gaaaaaggct atatccctaa
    10261 aataacaaca aacggaacat taattacaag agaattagct aaagagcttg caaattataa
    10321 aatattaaca ttacaaataa gtttagatgc cccaaataaa gaatgctatt ctaatataag
    10381 gggttcagaa acttattttg atagaatttt agaaagcatt gaatatttaa aagaatttaa
    10441 aatcccgatt tgcctttcaa tggtattgtt gaagacgaat ataaatttag tggaggattt
    10501 tataatattt gctaaaaaaa ttaaagtaaa tggtgttaga tttatagatt ttatccctaa
    10561 ttcaaatgaa aaaatgttgt tagtcccttc aaacgaagaa attaaaaaag cttatattac
    10621 aatgaacaaa tttgaaaata cacctgagtt taaaatcata aaaccatata agttactaag
    10681 cactttagta tttgacaaaa aaaatgaaat aaattattcg aactttactt tactgcaatg
    10741 ggttaacagg gaaaaaaagg ttatatgtga agcagcaaat attatagttc acataaaagc
    10801 taatggagat attacaccgt gtgttttttt tagagaaaaa aaatttattg ctggaaacat
    10861 actgcaaaat gattttttat ctatatggaa ccattcacca atcttcaatc tatttagaga
    10921 actttccaat aacaattgtc ctccttgtat tcattttagt acttgtatgg gtggttgtag
    10981 ggctcttgct tattatgtta ataaaaatct taatggtatt gacagtcgat gctggcataa
    11041 ttaatatgaa tggaggaaca aattgaaatg tttaagaaaa atgaatttat caatgtaagg
    11101 caagaaactg aagaagagta tattttcttt aatacaaaaa caggtgaaac tttcttacta
    11161 aatgatatag ggtatatcat ttttgagtgt gctctcaaat ctatgagcat gtccgatttg
    11221 gtaaaaaatg tatgtcaaaa aactaacgat gatattgaag tggctaataa aactatagaa
    11281 aactttataa aaattctatt agagaaaaac attctaattc agggagatac taaagaatga
    11341 aaaacaatag aaatgctatt aacttgttat gctctcaatt tatatcagag attggaaatt
    11401 ggattgatag ggttgcttta cttacattag tgtataacgt tagtaagtca agtttacaaa
    11461 tgtctattct ttctatttta atattatcac ctgctattat atttggtatt ccatttggga
    11521 aaataattga tttatcaaac aaaaaaacaa ttttggtatt tggagatatt tcgagagcgt
    11581 tattagtaat attagtgcca tatttcacca attatgtgtt tttgattgtg tttattatat
    11641 cttctgtcac cgctatttat gaaaatacaa gaaatagtat tataccagaa ctaaccacca
    11701 aagaagaaat acgtaaaatt aacagtctca gtagctcatt aaattccatt atgatggtta
    11761 ttggtccctc aataggtggg ttattaactt cttatcttaa tttgaaatat tgttttttta
    11821 ttgattcatt tacctttctt gtttctgcca tttttgtttc tcagatttcg taccataaat
    11881 atgaaagcac tgaaaataaa agtagaaata taagatattt ggaattttta aaatatttga
    11941 aatctaactt tatcataaaa agtttaataa ttctcaatgg tttgattggt ttatttgcag
    12001 gaattctaaa cggactgtta atcgtttatg tgattaacta tttacatact gattcaaaag
    12061 gatatggttt tattctgaca tcaaaaggaa ctgcaatggt tattacctca ctttatgttt
    12121 ataaatatat aaaaacaata aaaaatgaga ccctcctttt aacaggagta ataggtattg
    12181 gtatttctac tactttattc tcattaagta atatttttgt ctttgctctt ttcatccatt
    12241 ttgtgaatgg aatatgtaat tcattttatg ctattgctcg aactactata atccaagaaa
    12301 attgtaacaa gaaactatta ggaagagttt ttagctttaa ttcaatcgtg ggaaatatct
    12361 cctcaattat ttcattatta attggaggaa ttatatctaa tactatatct gttaagacaa
    12421 ttttcttaac cagcggaatt agcattgcat taataggaat ggtttatttt attaatttaa
    12481 aaaaactatc atgaaatact tcagcacggt aaataaaata atacacaaaa tctttttaaa
    12541 cagcgagact acacaaataa tttgtagtct cgcaaaactt tcattcaaac tttctcaaaa
    12601 actggttata aaacttgtat gtcatataaa catcaacctt gcttgttatt tcaaatgttg
    12661 agtgcataga taaaactgga acgcctgagt ctattacatt tatcattttt cttgcgataa
    12721 acagagcaat tgtacctcca ccgccttgat caactttacc taaaagacct gtctgccagc
    12781 aaatgttatt tgaattcaaa aagtttctga ttttgcctac atactctgct gttgcttcag
    12841 aaccactata tttgcctcta acccctgtat acttttcaat agtgacacca tggccaatta
    12901 acgtagaatt gagcttatca taagcacctt catatgttgg gtcaagtgct gctgcaacat
    12961 cgccagaaat tgctgctgag ttttcaaagc aaagagccaa atcaaggcta ttctcgtact
    13021 cacccaatgc tttcattagc tttgcaactg atacatcaaa aaagcttgcc tcagcgcttg
    13081 atattcctac acttcctatt tcctctttgt caaccaaata gaccagcgca gttttttccg
    13141 gagtttcatc tattgaaaag atgccttctg ctgctaaaaa actgcatgct ctgtcatcct
    13201 gaccatatgc gccaattagg cttctgtcaa gccccacatc acgtgctttt gcagcaggca
    13261 caacctcaat gtcagctgaa ataagatcct cttctgtaat accatatttt tcattcagaa
    13321 tcttcaagac attaagtttt accttttctt tcactttctc atcattaaac ggcatacttc
    13381 ctatgagcac attcaagttc tcagcgggaa ttgcctcgct tgcttttttc tgaagctgat
    13441 cagaagacaa gtgaacaaga aggtctgtta tataaaaaac agggtcattt tcatcttcac
    13501 caattgtaat cttcactttt gagccatcac ttttcacaac aactccgtgg atgctaaggg
    13561 gtacatttac ccagtgatat tttttaatgc caccataata gtgtgtcttc aaaagtgcaa
    13621 gttcatttga ctcatatagt ggctttggct tcaaatcaag tcgtggagaa tctatatggc
    13681 tacctatcag attaaatcct tctttcaatg gttttttccc tatatgagca agcaaaatgc
    13741 ttttgttatt gttgacaaaa tataccttat cacctggctt taatttttgg atattactgt
    13801 taaattcttt atatcctttt tctttagctc tttctatgaa atattcaact gcttctcttt
    13861 ctgtctttgc acagttcaaa aagtgcttat acttttctgc caaatcaaaa acaaaaggct
    13921 tttcttcttc ttttaaaact tcccatgcat ttttagaagt gtaggataat ttttcataaa
    13981 gctcttggcc ataagacttc tcgctcattg tctatacctc caatatattt tagtgtcgaa
    14041 aatgcccagt tcctatttaa atattttttt tagcttcata caaactatga tatcacaatc
    14101 atcttttttt gggtattaat tttaatataa gagcttgaga taagatttac tatttatcat
    14161 tcaccactta agaagatatt tcataaaatt acttgagaag aaaggtgtga aaggcagcac
    14221 aaaatgcaaa acgcaaggga aatactcaaa tatataggac caggacttct tgttaccgtg
    14281 ggatttatcg accctggaaa ctgggcatca aacgtggctg caggaagcca gtttggttta
    14341 aaacttttgt gggtagtttt actatcaacc ataattttga tagtgcttca gcacaacgca
    14401 gctcatcttg gcattgcaac aggtctttgc ttggctgaag caacttcaat ctatcttaat
    14461 aaatctcttg ccatagtggt gctctcatct gccatgctgg caacagtctc aactgctatg
    14521 gcagaaatct taggagcgtc aattgccctt gagatgcttt ttaaaattcc tattaagctt
    14581 gggtgtttaa tcatcctgcc ttttaccatg tttttcttgt tttctaactc atataaaaag
    14641 gttgaaaggt ggataattgc gtttgtgtcg ctgataggtc tttccttttt gatagagctt
    14701 tttcttgtga aggtccctgt aaaagatgtg gtcattggct ggataactcc aagcatacct
    14761 tctggttcac taattgttgt tctttcaata cttggtgcgg ttgtcatgcc acacaatttg
    14821 tttttacatt ctgaaataat tcagagcagg cagtggaaca ctcaagacga aaaggtaata
    14881 aaacatcagc tcaaatttga gtttgttgat acactttttt caatgtttat aggattttta
    14941 attaacagca gcatgattat aatagctcac acaacctttt acacaaaagg tatctttgtt
    15001 gaatcgctac cacaggctca gcagatgtta aagcctattt tgggaaattt ctctgcaaca
    15061 atttttgcat ttgctctatt gctttctggc atctcctcaa gcataacagc tgcatataca
    15121 ggtggaacaa tcatggcagg gttttataga aggccttaca acatagaaga gctgccaact
    15181 aaagttggaa ttatcattcc attggtgtta gcatctatca tcatagtttt tatctcaaat
    15241 ccgttcagag ctttaatact ctcacagatg ctattgagta tccagctacc aatcacaatc
    15301 attcttcaaa tttatttgac gtcatccaaa aaagtcatgg gtaaattcgc aaactcttta
    15361 gcagataaga taattcttgg aattgtggca gctttagtaa taggacttga tgtttttctg
    15421 ctcataacta ctttataaaa ataaaagtgg gcagatgaaa agaaaaacac tttgcctgcc
    15481 cacttcttta tttttttact tccttgaaga atagtcacga atgaagtttt ctattgaacg
    15541 gtcatatgtc ctttctgctt cttttgaaaa atagcaagca ggaagctgtc catttttcct
    15601 gtgatagtgc aaacactcgc agcatcttcc ttttcttgga cacggttcat aagtacatgt
    15661 gcagattgaa aggttttttg aaagtgtgca ctccatatta ccctttttcc ccctttttac
    15721 tgaagtttta ttttctttac tttctcttcg aaaaagatgt ataaaaaatc tccattttca
    15781 attttattat cttctataaa cctttcaatg tcaaatccga atatgcaagc ccttgatctt
    15841 ctaataatct cttttggttc tccgatatct tggtattctg ggctgactct gtatattgct
    15901 tgtttaattt tctctttttc ctctttcgac actgccaatt cctctggcaa aaattcttcc
    15961 ggaaaccttc ttagaatgtc aaatctgaac aagttatcaa atacagcctt gtcaaaatca
    16021 aaattctctt ttatggctat gtaaagctct tttataaact cccttgtgtt taaattgcta
    16081 ttcactttgc ttgagagctt ttcaaaaaat tcagaaggag aaattttttg aaagatgtat
    16141 cttaaagtaa aatagaggta ctgcctgttg taaactttgt ctatcaaatc ttctattttt
    16201 ttaagctcat aaatctcttc aaagctaata aagctatttg agataacctc atacggcgga
    16261 tctttgaaaa actcataatt gtatttagct gcttcttctc ttatctttgt tccttttaac
    16321 atcttcaaaa atccaagttg aacttcgtcc gcaaaataca atatagtttt atcaagactt
    16381 cttttaaaac tcaaaaaatc ttcatatggc aagcctgcta tcaagtcaag atgaacaatg
    16441 gcctttttgt tctccataag ctctttcaag tttttatcaa ttttatctat atcataaaat
    16501 ctatcaattg catcaagagt ttgtggattg aaactctgaa gacctatttc aagtctgaag
    16561 agattatctt ttgaagtatt tattgcagtg ataatgtcac tatctaaaag tgttgggtct
    16621 atttcaaagt gtatttgggt agcttgcgac ttttgtttac aaaactctat tatttttatt
    16681 gctctttctt tgtttgcgtt aaatgtcctg tcaacaaact ttataagtct tacttgtttt
    16741 ttaaaaagat agtcaagctc ttcgaacacc ttttcaagag acgcaaatct aacacttttt
    16801 tcaatagaag aaagacaata cgtacatcta aaagggcagc ctctgctgct ttcataataa
    16861 tagattctgc tttggtctaa cttctcgtcc ttgtacgcaa aaggaagttt gttcaaatca
    16921 aacggcggat actctttttg ggtatattgc ctgccagccg caatatggtc acataaatct
    16981 aaaaaagggt actctccctc tcctctgatt attatgtcaa caaacttcca ctcatcaagg
    17041 ctgtcaaaat acacttctgg cccgccaaga attattttta tgtctttcct tgcctttttt
    17101 aatccttcaa caagtttttc gacatagctt ctgttccaga tatatgttga aattgcaaca
    17161 tattcaggtt tcttactcaa aatctcatag agcacatcat gcaaagactg attgatatta
    17221 aactcaacat attcgcatgg atagttttct ttacagagct gataaaggta tctgactgct
    17281 aaatttgtat gaacatactt tgagtttatt gcaacaagca ggatcatagc gattttcctt
    17341 tctgaataat aattaattat tgtctcatta ttatatcaca gtttttattt caaaagagct
    17401 aaaaaacaaa aaggcagggt ttttcctgcc tctattagtt aagattcccc taacttagat
    17461 aaacagattc acacctgctt cgcttgcctc accaagatat gtggcaacac caccaatttc
    17521 aacaccatca attaactctt ctttttttat ccccataaca tccattgaca ttgaacatgc
    17581 aaccatcttt ataccaagct cttgcgcttg ttttatcatc tcaggtaaca tcatcacgtt
    17641 tttctttttc atcatatatt tcataagctt tggaccaatc cctaaaaagt tcatctttga
    17701 aagtggaagc ttttcaaccc cttttggcat catagcacca aacatttttt ctaaaaatga
    17761 ttttccctgt gctttctttt tagcatctct tagaacattc aaaccccaga atgtaaaaaa
    17821 cattgtcact tcatcgccca tcgcagcagc accagttgca attacaaatg cagccatcac
    17881 cttgtccatg tcattgctaa agacaataat ggtcttctta tcctctctca tacaaatcac
    17941 cctttaagct ttctttatct tagcttttat aacatcattt acttcttcta aagacaaaag
    18001 ttcatttttt gtctttttac accagctctc cacatctctt ttgaatgctg gatctgtcac
    18061 ctcaattgtg actatgtcac cactttgagc ttctttcatc tgcttaaaaa gttgagtaat
    18121 aggccccgga cactgaagac cctttgcatc aataaaatat tctgccacaa tcacacacct
    18181 ccaaaaactt tatttttaac tttttatatt gttacccctt ggcaatagga tttatttaac
    18241 aaaagcacac aataaaattc tttacaaaac actttgttaa aataataaca cttttacaca
    18301 aaatacaatg tctcaaatga gtttaaaaaa agaaagacac tcttgacttt ttaggagttt
    18361 ttttacccca aaaacttcat cattatattt aaaatccttt ggatatcatc tttgtttcct
    18421 acgcttgaca agcactctgc agcatgactt tcgattataa aataaccaac tttttctatt
    18481 gcgtttttta ctgcagctat ttgaagcata atctcttcgc attctttttc ctcttccacc
    18541 attttaataa taccatcaat gtgaccttta atatttttta gtctacttag aatctcttct
    18601 tttctctcct tgtcaggcat ttcaaacacc tactcttcaa caatttcaat tgcaccttga
    18661 ggacaatacc ttgtacaacc cccacatcct gtacactttt ctttgtctat ttcaatctca
    18721 acatcaaaaa aaccgcgcac ttttctcttt attgctccaa acttgcacga acgtgaagct
    18781 gggcaaaatg gtgacctatc acatagattt ttgttaagta ctgccttttt cattttctac
    18841 ctttttctcc tctcccaaaa tgttttgcaa cctctttttg taacccctat accatggggg
    18901 tgtattttaa tttttaagtt tattataact caaaaatgca atataatcaa tccccaaaag
    18961 gaaagtttga aaaccttttt cttagggtat aacatctttt gataaaatat gttataatta
    19021 aatagtaaca aatttataca cgggaggttt tataatgaaa aagctatgta agatgtatct
    19081 ggtttttttt attgtctttt tgctcatttt caacgtggca tttgctcagt caattaaagt
    19141 aactccaaaa gtaattaatg gcaaaatgta tgtggatttg gattctttga aagatttttt
    19201 cggttttgat tatgtaaaat cccaagatgg agtgaccatt caaaaaaagg acttatctat
    19261 aagcgaagta attgataaag ttaacaaatc tgttgtagca ataattggtg acagcaaaaa
    19321 gataaaagca gatgactttt actacagcaa gatacctgca gggcttacgc acgggtctgg
    19381 tgttgtcatt gacaaaaacg gtttaatcct cacaaacaac catgttgtag aagacatgaa
    19441 acaaccttat gtgatttttt atgatgctaa agcatataaa gcaacagtat tgtatagaaa
    19501 taaagacata gatttggctc ttttgaaagt aaatcgtacc aatataaatc caatcgaaat
    19561 cgaagacccc aaaaatataa aagtgggaca agaagtatta gcaattggaa ctccactttt
    19621 tttgggttgg cagaacagtg taacaaaagg aataatcagt ggattaaaca gaccagtaga
    19681 tgaaacttat acatttttgc aaacagatgc agctataaac cctggaaata gtggaggtcc
    19741 tcttgtaaat atgcaaggga agttggttgg cataaatacc ttaggtattg aatattttca
    19801 gggaattaat tttgcaattc ctgctgaaaa tattctctat tttttgaacc actataaaaa
    19861 atttggtaaa ataaaaagat gttatttagg acttgaattt gaagacagct ggctttctat
    19921 tgttggtttg ccatctactc ttggattgaa aataattgat gtgaaagaag atagtccttt
    19981 aaaaggattt attcaagaaa atgatatact tgtgtcaatt gacaattatc ctgtcaattc
    20041 aattgcagag tataatcaaa cccttatgaa atatcttcca ggtgataagg taaagattaa
    20101 tatcaagaga aacggaaagg taattgaaaa agaagtagtg ctaaaagagt atccagaaaa
    20161 taaataaaaa catagaaagg atgatatttg atggtaaaga aattaaaaag atttttaata
    20221 gcttccctac ttgtcacttt tctgatctct ttggttgctc cttttagttt tgctcaggat
    20281 gatgatggag ttattgactt ttacacagtt ttttcaaaag atgatgtcaa caaaaataga
    20341 gttggaaata gcatttacaa ctggtcaata tacatgcccc aagatgctta tattaacaaa
    20401 gacccaaaag gaagttattt ttcaatgtct agcagtagct ataaagcaaa tataagtgtt
    20461 gaagcaattc taaacaaaga aggcttttct tccttagatg aaattttgtt gtacggctca
    20521 gacattataa ataattatgg ctcggtttct aaaatatatt cgttgaaaaa aggtaaagat
    20581 aaaaatgggc aagagtacat tgaaatcaca agtgtctata cagattcttt ttacgttttt
    20641 gtagatgaag aagaaagttc tggcaccttt aattttacac gtatttatct tagcaaaaac
    20701 aagaagtata actacattta tagactcaca atcagcatgg acttaaactt ttataccgag
    20761 cataaaaatc ttctgtataa aatagctgat tcatttgaac ttcagtttga ttcaaaaaac
    20821 cctaatataa aggatttagc agacaacgta acaagctgga gagttcataa aaatacaagt
    20881 tatggctggc agattgacct gccaccttat tggaaatcaa ctgacattta taaccttgaa
    20941 tataactcat caacccagtc ttttgcccca ctttatacag atgaagaaat ggggttaaat
    21001 actcaaaaac agcaagatgt agttacaacg ccaccacaag gtgagcagca agagtatgac
    21061 gaatatctct ctgtcagttt tgttgctaat tcaaatgtaa gttttgacaa gtgggttgaa
    21121 cttgagatga aaaacgttga gctttataac aaatctcttt gcaagataat ttcttctaaa
    21181 actttaaata taaatggtgc aaaagccaaa ctctttgagc tcaatataag aaagagcctc
    21241 cagaaaaatt tcgttgaaaa aagaatgtat gtggacttca ataacaacaa atattttgta
    21301 aagctttatg tcaaagagga caaatataac aaagacaaac
//
