LOCUS       NZ_JH594500.1          20267 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JH594500.1 Segatella maculosa OT 289 supercont1.1, whole genome
            shotgun sequence.
ACCESSION   NZ_JH594500
VERSION     NZ_JH594500.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:27:12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 214665
            Orig. end    :: 234932
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20267
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[224665:224932](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10267
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20267
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20267
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="2"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(80..529)
                     /locus_tag="ctg1_164"
                     /transl_table=11
                     /translation="MIPLNLPDYEIKLSGTPTKPTIFDILRRKYVALTPEEWVRQHFVH
                     FLINHKGYPATLLANEVRLKIGNKTLRADTVLYSRELKPRIIIEYKAPHIAITQKVFDQ
                     ITTYNMLLHVDYLIVSNGIQHYCCKMDYDYQKYLYLGDIPDYQEI"
     PFAM_domain     complement(98..427)
                     /aSDomain="HSDR_N_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13588.8"
                     /description="Type I restriction enzyme R protein N
                     terminus (HSDR_N)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_164_0017"
                     /evalue="2.50E-40"
                     /label="ctg1_164"
                     /locus_tag="ctg1_164"
                     /protein_end="144"
                     /protein_start="34"
                     /score="137.0"
                     /tool="antismash"
                     /translation="PEEWVRQHFVHFLINHKGYPATLLANEVRLKIGNKTLRADTVLYS
                     RELKPRIIIEYKAPHIAITQKVFDQITTYNMLLHVDYLIVSNGIQHYCCKMDYDYQKYL
                     YLGDIP"
     CDS             642..1676
                     /locus_tag="ctg1_165"
                     /transl_table=11
                     /translation="MPEKKNTGTSYETIMRDLKARHFSPIYILMGDESYYIDKISDYIA
                     EHVLRPEERDFNQTVVFGSDISASQIVDSAKAFPMMAEKRVVIVKEAQNLKGTEPLVKY
                     FKQPVVSTVLVLCHKNGSIDKRKKIIPAAQVGGAVIFESKKLYERELPGFITSYFMQHE
                     ITIEQKAAQMIADHVGADLHRLTSELDKILISFSEVDRMVTPEIVEKEIGVSKDFNAFE
                     LRSAIIQRDVYKANLITKYFDNNPKAGSLFSFLPMLFSYFENLMIAFYSPNRSNENALV
                     QFLELRNGWAAKDYLTGLRNYSGMKTMQIISKIREIDAKSKGLDNPNTASSELMKELIF
                     FILH"
     aSDomain        711..1643
                     /aSDomain="TIGR01128"
                     /aSTool="tigrfam"
                     /description="holA: DNA polymerase III, delta subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_165_0001"
                     /evalue="2.20E-42"
                     /identifier="TIGR01128"
                     /label="ctg1_165"
                     /locus_tag="ctg1_165"
                     /protein_end="334"
                     /protein_start="23"
                     /score="143.4"
                     /tool="antismash"
                     /translation="SPIYILMGDESYYIDKISDYIAEHVLRPEERDFNQTVVFGSDISA
                     SQIVDSAKAFPMMAEKRVVIVKEAQNLKGTEPLVKYFKQPVVSTVLVLCHKNGSIDKRK
                     KIIPAAQVGGAVIFESKKLYERELPGFITSYFMQHEITIEQKAAQMIADHVGADLHRLT
                     SELDKILISFSEVDRMVTPEIVEKEIGVSKDFNAFELRSAIIQRDVYKANLITKYFDNN
                     PKAGSLFSFLPMLFSYFENLMIAFYSPNRSNENALVQFLELRNGWAAKDYLTGLRNYSG
                     MKTMQIISKIREIDAKSKGLDNPNTASSEL"
     PFAM_domain     720..1217
                     /aSDomain="DNA_pol3_delta"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06144.15"
                     /description="DNA polymerase III, delta subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_165_0018"
                     /evalue="5.40E-24"
                     /label="ctg1_165"
                     /locus_tag="ctg1_165"
                     /protein_end="192"
                     /protein_start="26"
                     /score="85.0"
                     /tool="antismash"
                     /translation="YILMGDESYYIDKISDYIAEHVLRPEERDFNQTVVFGSDISASQI
                     VDSAKAFPMMAEKRVVIVKEAQNLKGTEPLVKYFKQPVVSTVLVLCHKNGSIDKRKKII
                     PAAQVGGAVIFESKKLYERELPGFITSYFMQHEITIEQKAAQMIADHVGADLHRLTSEL
                     DKI"
     CDS             2317..2766
                     /locus_tag="ctg1_166"
                     /transl_table=11
                     /translation="MESQHMTQQTFAQFIQISPASLSSIFNGRTKPTLTVVEAIRSKIP
                     SLSLEWLMFGVGPMYNNDKAKSNLEVVEGTFAAKEGLNHFGEQTKSPTPSLFDQDQERI
                     QNIGNTLIDNKEKTVKIIDKPQRKISEIRIFYDDRTWETFVPQKS"
     PFAM_domain     2320..2472
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_166_0019"
                     /evalue="2.90E-08"
                     /label="ctg1_166"
                     /locus_tag="ctg1_166"
                     /protein_end="52"
                     /protein_start="1"
                     /score="33.7"
                     /tool="antismash"
                     /translation="ESQHMTQQTFAQFIQISPASLSSIFNGRTKPTLTVVEAIRSKIPS
                     LSLEWL"
     CDS             2826..3602
                     /gene_functions="other (smcogs) SMCOG1094:ferredoxin
                     (Score: 63.4; E-value: 3.1e-19)"
                     /gene_kind="other"
                     /locus_tag="ctg1_167"
                     /transl_table=11
                     /translation="MKKFVQDLTVKSVEILSSKHVLLKLTAEESLPPTIPGQFVEVRVD
                     NSPSTFLRRPISINLVDYQQNELWLLIAMIGDGTQQLGKLKVGDTLNCLYPLGNGFTLP
                     NDSSEKILLIGGGVGIAPLLYLGHEIKANKGKPTFILGARTKNELLELDLFQQLGRVFI
                     TTEDGSMGEKGFVTNHSILQKEKFSSISTCGPKPMMMSVAQYAYANDIQCEVSLENKMA
                     CGLGACLCCVEKTVDGNICICKEGPVLNIKKLLWQI"
     PFAM_domain     3162..3434
                     /aSDomain="NAD_binding_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00175.23"
                     /description="Oxidoreductase NAD-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_167_0020"
                     /evalue="2.80E-06"
                     /label="ctg1_167"
                     /locus_tag="ctg1_167"
                     /protein_end="203"
                     /protein_start="112"
                     /score="28.1"
                     /tool="antismash"
                     /translation="LIGGGVGIAPLLYLGHEIKANKGKPTFILGARTKNELLELDLFQQ
                     LGRVFITTEDGSMGEKGFVTNHSILQKEKFSSISTCGPKPMMMSVA"
     PFAM_domain     3477..3587
                     /aSDomain="DHODB_Fe-S_bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10418.11"
                     /description="Iron-sulfur cluster binding domain of
                     dihydroorotate dehydrogenase B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_167_0021"
                     /evalue="1.60E-10"
                     /label="ctg1_167"
                     /locus_tag="ctg1_167"
                     /protein_end="254"
                     /protein_start="217"
                     /score="40.6"
                     /tool="antismash"
                     /translation="ENKMACGLGACLCCVEKTVDGNICICKEGPVLNIKKL"
     CDS             3590..4495
                     /locus_tag="ctg1_168"
                     /transl_table=11
                     /translation="MADLNVKISNLQFKNPVMTASGTFGYGLEFADLVPLHEIGGIIVK
                     GTTLHSREGNDSPRMVETASGMLNCVGLQNKGVDYFCKHIYPQIRDIDTNIIVNVSGDS
                     AETYAECARRINELDAVPAIELNISCPNVKEGGMAFGVSCAGAAGIVKAVRAVYQKTLI
                     VKLSPNVTDIVSIARACEEEGADAVSLINTLMGMAIDIEKREPLLSIRTGGLSGPAIKP
                     VALRMVYDVAHAVKIPVVGLGGISSTEDAIEFMMCGATAIEIGTANFIDPTITKKVKDG
                     ISSWLDAHGCRSIQEIIGVV"
     PFAM_domain     3599..4444
                     /aSDomain="DHO_dh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01180.23"
                     /description="Dihydroorotate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_168_0022"
                     /evalue="4.00E-74"
                     /label="ctg1_168"
                     /locus_tag="ctg1_168"
                     /protein_end="285"
                     /protein_start="3"
                     /score="249.6"
                     /tool="antismash"
                     /translation="LNVKISNLQFKNPVMTASGTFGYGLEFADLVPLHEIGGIIVKGTT
                     LHSREGNDSPRMVETASGMLNCVGLQNKGVDYFCKHIYPQIRDIDTNIIVNVSGDSAET
                     YAECARRINELDAVPAIELNISCPNVKEGGMAFGVSCAGAAGIVKAVRAVYQKTLIVKL
                     SPNVTDIVSIARACEEEGADAVSLINTLMGMAIDIEKREPLLSIRTGGLSGPAIKPVAL
                     RMVYDVAHAVKIPVVGLGGISSTEDAIEFMMCGATAIEIGTANFIDPTITKKVKDGISS
                     W"
     aSDomain        3599..4489
                     /aSDomain="TIGR01037"
                     /aSTool="tigrfam"
                     /description="pyrD_sub1_fam: dihydroorotate dehydrogenase
                     family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_168_0002"
                     /evalue="1.50E-111"
                     /identifier="TIGR01037"
                     /label="ctg1_168"
                     /locus_tag="ctg1_168"
                     /protein_end="300"
                     /protein_start="3"
                     /score="370.2"
                     /tool="antismash"
                     /translation="LNVKISNLQFKNPVMTASGTFGYGLEFADLVPLHEIGGIIVKGTT
                     LHSREGNDSPRMVETASGMLNCVGLQNKGVDYFCKHIYPQIRDIDTNIIVNVSGDSAET
                     YAECARRINELDAVPAIELNISCPNVKEGGMAFGVSCAGAAGIVKAVRAVYQKTLIVKL
                     SPNVTDIVSIARACEEEGADAVSLINTLMGMAIDIEKREPLLSIRTGGLSGPAIKPVAL
                     RMVYDVAHAVKIPVVGLGGISSTEDAIEFMMCGATAIEIGTANFIDPTITKKVKDGISS
                     WLDAHGCRSIQEIIGV"
     CDS             4449..4565
                     /locus_tag="ctg1_169"
                     /transl_table=11
                     /translation="MHMAVEVSKRLSESFDFNHTFCFNVSWISALERESKKQ"
     CDS             4701..5330
                     /locus_tag="ctg1_170"
                     /transl_table=11
                     /translation="MFSAKSTIFAKRLIYLFYLSIMEKSLNKYIVASYKLYDVTEGKKE
                     LVEETSADRPFVFLSGFGVTLPAFEDALVNLGKGECFDFSLTAEQAYGAYYQERVIELD
                     KSVFKVDGKFDEAHIVVGAIVPLQNEDGNRFNGRILTVTADKVKVDLNHPFAGKKLNFV
                     GKVIESHEADSEEITDFVNMLNGESGCGGCSGRCGGGNCEGGCGCH"
     CDS             5349..6428
                     /locus_tag="ctg1_171"
                     /transl_table=11
                     /translation="MVRNSFGNIFVLTTFGESHGVAIGGVIDGMPAGIEIDFDFIQNEL
                     KRRRPGQSKITTSRSEPDKVEFFSGVFEGKSTGAPIGFAVYNTDQHSKDYDNMRALFRP
                     SHADFTYYKKYGERDYRGGGRSSARVTIARCVGGALAKLVLRKLHIDIKAYTSQVGSII
                     LENDYYKYDLNTIEDNIVRCPDQRKATEMAELIEQVKNEGDTIGGVVSCVIKGCPVGLG
                     EPEFGKLHAQLGAAMLSINAAKGFEYGMGFAGVGKRGSEQNDVFYSQKGNISTVTNHSG
                     GVQGGISNGQDIFFRVAFKPVATLLMPQETVDEHGDATSFHAHGRHDPCVLPRAVPIVE
                     AMAAMVVLDNYLLNLTIKV"
     PFAM_domain     5376..6404
                     /aSDomain="Chorismate_synt"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01264.23"
                     /description="Chorismate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_171_0023"
                     /evalue="8.40E-138"
                     /label="ctg1_171"
                     /locus_tag="ctg1_171"
                     /protein_end="352"
                     /protein_start="9"
                     /score="458.7"
                     /tool="antismash"
                     /translation="FVLTTFGESHGVAIGGVIDGMPAGIEIDFDFIQNELKRRRPGQSK
                     ITTSRSEPDKVEFFSGVFEGKSTGAPIGFAVYNTDQHSKDYDNMRALFRPSHADFTYYK
                     KYGERDYRGGGRSSARVTIARCVGGALAKLVLRKLHIDIKAYTSQVGSIILENDYYKYD
                     LNTIEDNIVRCPDQRKATEMAELIEQVKNEGDTIGGVVSCVIKGCPVGLGEPEFGKLHA
                     QLGAAMLSINAAKGFEYGMGFAGVGKRGSEQNDVFYSQKGNISTVTNHSGGVQGGISNG
                     QDIFFRVAFKPVATLLMPQETVDEHGDATSFHAHGRHDPCVLPRAVPIVEAMAAMVVLD
                     NYL"
     aSDomain        5379..6410
                     /aSDomain="TIGR00033"
                     /aSTool="tigrfam"
                     /description="aroC: chorismate synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_171_0003"
                     /evalue="1.40E-136"
                     /identifier="TIGR00033"
                     /label="ctg1_171"
                     /locus_tag="ctg1_171"
                     /protein_end="354"
                     /protein_start="10"
                     /score="453.0"
                     /tool="antismash"
                     /translation="VLTTFGESHGVAIGGVIDGMPAGIEIDFDFIQNELKRRRPGQSKI
                     TTSRSEPDKVEFFSGVFEGKSTGAPIGFAVYNTDQHSKDYDNMRALFRPSHADFTYYKK
                     YGERDYRGGGRSSARVTIARCVGGALAKLVLRKLHIDIKAYTSQVGSIILENDYYKYDL
                     NTIEDNIVRCPDQRKATEMAELIEQVKNEGDTIGGVVSCVIKGCPVGLGEPEFGKLHAQ
                     LGAAMLSINAAKGFEYGMGFAGVGKRGSEQNDVFYSQKGNISTVTNHSGGVQGGISNGQ
                     DIFFRVAFKPVATLLMPQETVDEHGDATSFHAHGRHDPCVLPRAVPIVEAMAAMVVLDN
                     YLLN"
     CDS             complement(6264..6680)
                     /locus_tag="ctg1_172"
                     /transl_table=11
                     /translation="MLSEASDGRKRKIKLFSEGSDDKKVKRNCHPRARMIKGAVVRCRR
                     SYRVGSFTPSCTLHRESDFCKFPGNISNSRYIIKAYMPISYFYCQVEKVVIQYHHCSHC
                     LDNRDSSREHTGVVASMCMKRSSISMLIYRFLWH"
     CDS             7210..8073
                     /locus_tag="ctg1_173"
                     /transl_table=11
                     /translation="MRQLKITKSITNRETASLDKYLQEIGHEELISVEEEVELAQRIRR
                     GDRQALEKLTRANLRFVVSVAKQYQNQGLSLADLINEGNLGLIKAAEKFDETRGFKFIS
                     YAVWWIRQSILQAIAEQSRIVRLPLNQVGSVNKIKRALNKFEQENEWYPSIEEIAKKVD
                     IPEEKIADAIKMNGRQISVDAPFTDGDDCTFLDIMPNSDALMADNVLVRESLQDEISNA
                     LQTLSERERNIIEAFFGINQSELTLEEIGDKFGLTRERVRQIKEKAIRRLRHHAKSKNL
                     KTYLGQ"
     PFAM_domain     7258..7353
                     /aSDomain="Sigma70_r1_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00140.22"
                     /description="Sigma-70 factor, region 1.2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_173_0024"
                     /evalue="3.70E-11"
                     /label="ctg1_173"
                     /locus_tag="ctg1_173"
                     /protein_end="48"
                     /protein_start="16"
                     /score="42.9"
                     /tool="antismash"
                     /translation="SLDKYLQEIGHEELISVEEEVELAQRIRRGDR"
     aSDomain        7357..8031
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_173_0004"
                     /evalue="1.90E-35"
                     /identifier="TIGR02937"
                     /label="ctg1_173"
                     /locus_tag="ctg1_173"
                     /protein_end="274"
                     /protein_start="49"
                     /score="119.9"
                     /tool="antismash"
                     /translation="ALEKLTRANLRFVVSVAKQYQNQGLSLADLINEGNLGLIKAAEKF
                     DETRGFKFISYAVWWIRQSILQAIAEQSRIVRLPLNQVGSVNKIKRALNKFEQENEWYP
                     SIEEIAKKVDIPEEKIADAIKMNGRQISVDAPFTDGDDCTFLDIMPNSDALMADNVLVR
                     ESLQDEISNALQTLSERERNIIEAFFGINQSELTLEEIGDKFGLTRERVRQIKEKAIRR
                     LRH"
     PFAM_domain     7375..7578
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_173_0025"
                     /evalue="2.90E-18"
                     /label="ctg1_173"
                     /locus_tag="ctg1_173"
                     /protein_end="123"
                     /protein_start="55"
                     /score="65.5"
                     /tool="antismash"
                     /translation="RANLRFVVSVAKQYQNQGLSLADLINEGNLGLIKAAEKFDETRGF
                     KFISYAVWWIRQSILQAIAEQSR"
     PFAM_domain     7612..7824
                     /aSDomain="Sigma70_r3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04539.18"
                     /description="Sigma-70 region 3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_173_0026"
                     /evalue="6.10E-13"
                     /label="ctg1_173"
                     /locus_tag="ctg1_173"
                     /protein_end="205"
                     /protein_start="134"
                     /score="48.8"
                     /tool="antismash"
                     /translation="VNKIKRALNKFEQENEWYPSIEEIAKKVDIPEEKIADAIKMNGRQ
                     ISVDAPFTDGDDCTFLDIMPNSDALM"
     PFAM_domain     7873..8031
                     /aSDomain="Sigma70_r4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04545.18"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_173_0027"
                     /evalue="8.40E-18"
                     /label="ctg1_173"
                     /locus_tag="ctg1_173"
                     /protein_end="274"
                     /protein_start="221"
                     /score="63.7"
                     /tool="antismash"
                     /translation="ALQTLSERERNIIEAFFGINQSELTLEEIGDKFGLTRERVRQIKE
                     KAIRRLRH"
     CDS             8117..8596
                     /locus_tag="ctg1_174"
                     /transl_table=11
                     /translation="MRLERFFLIVVVFSVCTTVFAGNKNKVFLCGFAASFNDSTVFFTD
                     IQEVDSAVIDKNHFLFGRDNYSYQLRDYLTSQGFEHATCVTLWATARDVIEKKYQKLRN
                     KYAVIAQKRTRRKKTAPLTVKYLTTEQFRYEAIVPEGNTVSATKQSAVKTKKTGK"
     CDS             8639..9526
                     /locus_tag="ctg1_175"
                     /transl_table=11
                     /translation="MDYYFEIAEHYIKISQLDGNIPLLSLLPSFQPFLCDAVSDEELLF
                     SFTIDNHLKAVDKSRRHPIRTFDTGNGDTVVDKLSDGGYQYVVKNINRDACALLICDKD
                     FRTCSCTLNGSLNMQSFGLNNALMLTMAFAGSKRDTVLIHASLVRNNDYGYAFIAKSGT
                     GKSTHVSLWLRFIPDCDLMNDDNPIIRLINGTPYIYGSPWSGKTPCYRKVKARLGAITQ
                     IARARENSIERLSVVNAFATLLPSCSSMKWDADIFNHICSIVSDIMAQTPIYTLHCRAD
                     RHAADLCHQTITAE"
     CDS             9523..9984
                     /locus_tag="ctg1_176"
                     /transl_table=11
                     /translation="VKKVFPNEQLIPEVISLIEQGHTVTLPLRGFSMRPFLEDNRDKAL
                     LTKPDRLKVGDPVLAEVRPKFYVLHRIIAIDGEHVVLRGDGNLACEHCLQKDVKAAVIG
                     FYRKKHNYLDRTDGLKWRLYSRLWLFLFPVRRYLLAFYRRVWIKCFGLI"
     CDS             10001..10267
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_177"
                     /sec_met_domain="PF05402 (E-value: 1.7e-16, bitscore: 55.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 3.6e-09,
                     bitscore: 31.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQGFILRNVCGENIIVAEGETNIDFSNIISMNETSAFLWNNI
                     QGKEFTHDDLVDLLTETYQVDAQKALEDVTRLVDNWKSAGIIE"
     PFAM_domain     10046..10261
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_177_0028"
                     /evalue="1.00E-14"
                     /label="ctg1_177"
                     /locus_tag="ctg1_177"
                     /protein_end="87"
                     /protein_start="15"
                     /score="54.7"
                     /tool="antismash"
                     /translation="NIIVAEGETNIDFSNIISMNETSAFLWNNIQGKEFTHDDLVDLLT
                     ETYQVDAQKALEDVTRLVDNWKSAGII"
     CDS             10313..10438
                     /locus_tag="ctg1_178"
                     /transl_table=11
                     /translation="MCMEMQNVSHEFLAMFISLRNDFSRFTSQSQSYQAIKWLRL"
     CDS             complement(10533..13019)
                     /locus_tag="ctg1_179"
                     /transl_table=11
                     /translation="MARKKSDRKPKSIGEAVGFRNIFSNEKTDFLLGLILLLIAIYVII
                     AMVSYFSTGQDDQSILESLRHGEWINSNRSITNYCGSIGAIVAYTLMSVNFGLPAFIIP
                     AFIVLVGLKLMSIYTINLWKWFFGMMLTMIWCSITFAKFLTPVMGNLFFNPGGNHGLFC
                     VQQLENIVGAPGLIVILLFTALAFLTYLSAETIFIIRKAMNPVKYLTSKVKFTVTNHEI
                     DTADSEHNAAADNNEETEDSNTINQGLPEDFPAPVVDLTDFGNIDKDTLPANAAPTLSV
                     TNNSEPQTANDNRLTVEIAKNEEKAGSAVVNLEDILSTPIDPLEPFTKYKKPTLELLKK
                     YDEEDKPNVDMEEIKANNARIVEVLNSFGVSIREIKATVGPTITLYEITPAEGVRISKI
                     RNLEDDIALSLSALGIRIIAPIPGKGTIGIEVPNKRPQIVSMESILNSKKFKETKMELP
                     LALGKTITNEVFMVDLAKIPHLLVAGATGQGKSVGLNAIITSLLYKKHPNELKFVLVDP
                     KKVEFSVYHKISGHFMACLPENEEEPIITDVTKVVRTLNSLCALMDHRYDLLKMAGAKN
                     LKEYNAKFVNHKLDLTKGHDYMPYIVVIIDEFGDLIMTAGKEIELPIARIAQLARAVGI
                     HMVIATQRPTTKIITGNIKANFPGRMAFRVSSQIDSRTILDRSGANQLVGRGDLLFLNG
                     NEPVRVQCAFVDTPEIEHINDYISEEPGPIEPMELPEPIEDNSGGSIGDGATDISSLDP
                     YFEEAAHAIVLSQQGSTSMIQRRFSIGYNRAGRLMDQLEHMGIVGTAQGSKPREVLIQD
                     ENQLNALIMQLRNRQA"
     PFAM_domain     complement(10590..10769)
                     /aSDomain="FtsK_gamma"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09397.12"
                     /description="Ftsk gamma domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_179_0032"
                     /evalue="2.70E-27"
                     /label="ctg1_179"
                     /locus_tag="ctg1_179"
                     /protein_end="810"
                     /protein_start="750"
                     /score="94.3"
                     /tool="antismash"
                     /translation="LDPYFEEAAHAIVLSQQGSTSMIQRRFSIGYNRAGRLMDQLEHMG
                     IVGTAQGSKPREVLI"
     PFAM_domain     complement(11088..11690)
                     /aSDomain="FtsK_SpoIIIE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01580.20"
                     /description="FtsK/SpoIIIE family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_179_0031"
                     /evalue="3.80E-47"
                     /label="ctg1_179"
                     /locus_tag="ctg1_179"
                     /protein_end="644"
                     /protein_start="443"
                     /score="160.8"
                     /tool="antismash"
                     /translation="ILNSKKFKETKMELPLALGKTITNEVFMVDLAKIPHLLVAGATGQ
                     GKSVGLNAIITSLLYKKHPNELKFVLVDPKKVEFSVYHKISGHFMACLPENEEEPIITD
                     VTKVVRTLNSLCALMDHRYDLLKMAGAKNLKEYNAKFVNHKLDLTKGHDYMPYIVVIID
                     EFGDLIMTAGKEIELPIARIAQLARAVGIHMVIATQRP"
     PFAM_domain     complement(11721..12023)
                     /aSDomain="FtsK_alpha"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17854.3"
                     /description="FtsK alpha domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_179_0030"
                     /evalue="2.70E-30"
                     /label="ctg1_179"
                     /locus_tag="ctg1_179"
                     /protein_end="433"
                     /protein_start="332"
                     /score="104.6"
                     /tool="antismash"
                     /translation="PTLELLKKYDEEDKPNVDMEEIKANNARIVEVLNSFGVSIREIKA
                     TVGPTITLYEITPAEGVRISKIRNLEDDIALSLSALGIRIIAPIPGKGTIGIEVPN"
     PFAM_domain     complement(12444..12929)
                     /aSDomain="FtsK_4TM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13491.8"
                     /description="4TM region of DNA translocase FtsK/SpoIIIE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_179_0029"
                     /evalue="2.00E-16"
                     /label="ctg1_179"
                     /locus_tag="ctg1_179"
                     /protein_end="192"
                     /protein_start="30"
                     /score="60.3"
                     /tool="antismash"
                     /translation="LLGLILLLIAIYVIIAMVSYFSTGQDDQSILESLRHGEWINSNRS
                     ITNYCGSIGAIVAYTLMSVNFGLPAFIIPAFIVLVGLKLMSIYTINLWKWFFGMMLTMI
                     WCSITFAKFLTPVMGNLFFNPGGNHGLFCVQQLENIVGAPGLIVILLFTALAFLTYLS"
     CDS             13130..13780
                     /locus_tag="ctg1_180"
                     /transl_table=11
                     /translation="MKKTIYSKFDKKKITNLPIVQFPGRIITIVSETDADKAVDYLLSR
                     DILGVDTETRPTFHKGEQHKVALLQVASHDTCFLFRLNDIGMPASIIRLLEDQTVPKIG
                     LSWHDDILSLHRRTEFTPGYFIDLQNVIGEIGIKDLSLQKLYANLFHQKISKRQRLTNW
                     EADILNDKQKQYAATDAWSCIKLYEEVKRLHETKDYELIVPLEVTENNNDYAV"
     PFAM_domain     13211..13702
                     /aSDomain="DNA_pol_A_exo1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01612.22"
                     /description="3'-5' exonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_180_0033"
                     /evalue="6.20E-17"
                     /label="ctg1_180"
                     /locus_tag="ctg1_180"
                     /protein_end="191"
                     /protein_start="27"
                     /score="62.0"
                     /tool="antismash"
                     /translation="TIVSETDADKAVDYLLSRDILGVDTETRPTFHKGEQHKVALLQVA
                     SHDTCFLFRLNDIGMPASIIRLLEDQTVPKIGLSWHDDILSLHRRTEFTPGYFIDLQNV
                     IGEIGIKDLSLQKLYANLFHQKISKRQRLTNWEADILNDKQKQYAATDAWSCIKLYEEV
                     K"
     CDS             13814..15001
                     /locus_tag="ctg1_181"
                     /transl_table=11
                     /translation="MYKSVYLKKGKEESLNRFHPWIFSGAIHHMEEGIEEGDIVNVFTA
                     TNDFIAVGHYQIGSIAVRVLSFSEEEINHSFWCSHLESALKMRQRIGIADNENNNTYRL
                     VHGEGDALPGLIIDCYGETMVMQAHSVGMHASRKAVCRALVEVMGNRMKHVYYKSETTL
                     PFKAELEQENDFIHGGTDNDIAIENGLKFHVDWLHGQKTGFFIDQRENRSLLEHYAKDK
                     SVLNMFCYTGGFSVYAMRGQAKMVHSVDSSAKAIELTNRNIDLNFPGDKRHEAFCEDAF
                     KYLDNTDNANKYDLIVLDPPAFAKHRKALHNALKGYTRLNVKGLQRIKQGGILFTFSCS
                     QIVSKENFRNAVFTAAAQAGRKVRILHQLHQPADHPINIYHPEGEYLKGLVLYVE"
     PFAM_domain     13826..14014
                     /aSDomain="PUA_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17785.3"
                     /description="PUA-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_181_0034"
                     /evalue="1.30E-18"
                     /label="ctg1_181"
                     /locus_tag="ctg1_181"
                     /protein_end="67"
                     /protein_start="4"
                     /score="66.7"
                     /tool="antismash"
                     /translation="VYLKKGKEESLNRFHPWIFSGAIHHMEEGIEEGDIVNVFTATNDF
                     IAVGHYQIGSIAVRVLSF"
     PFAM_domain     14120..14845
                     /aSDomain="Methyltrans_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10672.11"
                     /description="S-adenosylmethionine-dependent
                     methyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_181_0035"
                     /evalue="1.20E-24"
                     /label="ctg1_181"
                     /locus_tag="ctg1_181"
                     /protein_end="344"
                     /protein_start="102"
                     /score="87.1"
                     /tool="antismash"
                     /translation="RLVHGEGDALPGLIIDCYGETMVMQAHSVGMHASRKAVCRALVEV
                     MGNRMKHVYYKSETTLPFKAELEQENDFIHGGTDNDIAIENGLKFHVDWLHGQKTGFFI
                     DQRENRSLLEHYAKDKSVLNMFCYTGGFSVYAMRGQAKMVHSVDSSAKAIELTNRNIDL
                     NFPGDKRHEAFCEDAFKYLDNTDNANKYDLIVLDPPAFAKHRKALHNALKGYTRLNVKG
                     LQRIKQGGILFTFSCSQIVS"
     CDS             14991..16334
                     /locus_tag="ctg1_182"
                     /transl_table=11
                     /translation="MLSSFAYGVKAFIDRNRLLKTDGFYLLALSGGCDSVALLRVMIEL
                     GYRFAAVHCNFQLRGEESQRDELFCEQLCLAQKVPFHRVHFDTKAYAKLHRVSIEMAAR
                     ELRYRYFEQLRKDLGADAILVAHHNDDSVETFLLNLIRGTGIHGLLGIKPKNGFIVRPL
                     LPIGRSDIEAYLSGIGQAFVTDCSNQIANVKRNMIRLKVLPLLREINPSVSDSITSTAK
                     RLGLVAQIFDKAMAESIAAVTSHQGADKCVIDIRQLKKETAPEYTLYSILKKYAFSSAQ
                     IESIACSLDAPSGRKWLSKSHELVVSRGQLIVVPLLQDANRSLSLPEPGRYVWDDVMKF
                     DVTLCDISSDFSPSRSKNIVTLAADSVRFPLLVRHVHKGDRFRPLGMKGSKLVNDLLTD
                     LKLSLDEKQRQLVVVDAADKIIWVVGRRIDDSVSVTSETTEILRLQIL"
     PFAM_domain     15063..15587
                     /aSDomain="ATP_bind_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01171.22"
                     /description="PP-loop family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_182_0036"
                     /evalue="5.10E-45"
                     /label="ctg1_182"
                     /locus_tag="ctg1_182"
                     /protein_end="199"
                     /protein_start="24"
                     /score="153.5"
                     /tool="antismash"
                     /translation="YLLALSGGCDSVALLRVMIELGYRFAAVHCNFQLRGEESQRDELF
                     CEQLCLAQKVPFHRVHFDTKAYAKLHRVSIEMAARELRYRYFEQLRKDLGADAILVAHH
                     NDDSVETFLLNLIRGTGIHGLLGIKPKNGFIVRPLLPIGRSDIEAYLSGIGQAFVTDCS
                     NQIANVKRNMIR"
     aSDomain        15063..15602
                     /aSDomain="TIGR02432"
                     /aSTool="tigrfam"
                     /description="lysidine_TilS_N: tRNA(Ile)-lysidine
                     synthetase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_182_0005"
                     /evalue="1.30E-48"
                     /identifier="TIGR02432"
                     /label="ctg1_182"
                     /locus_tag="ctg1_182"
                     /protein_end="204"
                     /protein_start="24"
                     /score="163.4"
                     /tool="antismash"
                     /translation="YLLALSGGCDSVALLRVMIELGYRFAAVHCNFQLRGEESQRDELF
                     CEQLCLAQKVPFHRVHFDTKAYAKLHRVSIEMAARELRYRYFEQLRKDLGADAILVAHH
                     NDDSVETFLLNLIRGTGIHGLLGIKPKNGFIVRPLLPIGRSDIEAYLSGIGQAFVTDCS
                     NQIANVKRNMIRLKVLP"
     aSDomain        16101..16235
                     /aSDomain="TIGR02433"
                     /aSTool="tigrfam"
                     /description="lysidine_TilS_C: tRNA(Ile)-lysidine
                     synthetase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_182_0006"
                     /evalue="2.60E-08"
                     /identifier="TIGR02433"
                     /label="ctg1_182"
                     /locus_tag="ctg1_182"
                     /protein_end="415"
                     /protein_start="370"
                     /score="31.2"
                     /tool="antismash"
                     /translation="LLVRHVHKGDRFRPLGMKGSKLVNDLLTDLKLSLDEKQRQLVVVD
                     "
     PFAM_domain     16110..16313
                     /aSDomain="TilS_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11734.10"
                     /description="TilS substrate C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_182_0037"
                     /evalue="1.10E-04"
                     /label="ctg1_182"
                     /locus_tag="ctg1_182"
                     /protein_end="441"
                     /protein_start="373"
                     /score="21.7"
                     /tool="antismash"
                     /translation="RHVHKGDRFRPLGMKGSKLVNDLLTDLKLSLDEKQRQLVVVDAAD
                     KIIWVVGRRIDDSVSVTSETTEI"
     CDS             16927..17994
                     /locus_tag="ctg1_183"
                     /transl_table=11
                     /translation="MADKNNHLVIMAGGVGSRFWPMSTAARPKQFIDVLGVGRSLLQLT
                     YDRFKGICLPENVWVVTNKDYAESCREQLPDVPAENILLEPCRRNTAPCIAYVSWRIKS
                     KDPRANVVVTPSDHIVTDTAEFRRVVASCLKFAGETDAIVTLGMKPTRPETGYGYIQAD
                     LSTASPRNKEIFRVDSFREKPDADTATKYIRQNNYFWNAGIFIWSVGTIVNAFRVYQPA
                     ISKVFEGMERIYGTAEEQSLIDERYPECESISVDYAIMEKAEEIFVCPADFGWSDLGTW
                     GSLLAESRKDLYGNSLIGDNITLFDSHNCIVHTMQEKQVVVQGLDGYIVAENDGRLLIC
                     KLSEEQRIKQFSENK"
     PFAM_domain     16951..17799
                     /aSDomain="NTP_transferase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00483.25"
                     /description="Nucleotidyl transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_183_0038"
                     /evalue="1.80E-41"
                     /label="ctg1_183"
                     /locus_tag="ctg1_183"
                     /protein_end="291"
                     /protein_start="8"
                     /score="142.5"
                     /tool="antismash"
                     /translation="VIMAGGVGSRFWPMSTAARPKQFIDVLGVGRSLLQLTYDRFKGIC
                     LPENVWVVTNKDYAESCREQLPDVPAENILLEPCRRNTAPCIAYVSWRIKSKDPRANVV
                     VTPSDHIVTDTAEFRRVVASCLKFAGETDAIVTLGMKPTRPETGYGYIQADLSTASPRN
                     KEIFRVDSFREKPDADTATKYIRQNNYFWNAGIFIWSVGTIVNAFRVYQPAISKVFEGM
                     ERIYGTAEEQSLIDERYPECESISVDYAIMEKAEEIFVCPADFGWSDLGTWGSLLAESR
                     KD"
     CDS             18002..19096
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 257;
                     E-value: 4.3e-78)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_184"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4e-11, bitscore:
                     37.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKTALITGITGQDGSYLAEFLLEKGYEVHGTIRRSSVDYRERI
                     AHLESHPHFHLHYADLSDSMSILGVVGQIRPTEIYNLAAQSHVQVSFDSPEFTADVDAV
                     GVLRVLEAVRQLGLTNSCRIYQASTSELYGKVEEVPQNENTPFHPYSPYAVAKQYGFWI
                     VREYRDAYNMFCCSGILFNHESERRGETFVTRKITLAAARIKQGKQDKLLLGNLSSLRD
                     WGYAKDYVECMWLILQHDKPEDFVIATGAQHSVREFCYYAFKRVGIELEFKGEGIDEKG
                     IDKATGKVLVEVSPDFYRPTDVVNLWGDPTKAKAELGWNPDKTSFEELVNLMVDSDMAK
                     VASEGAAEKVRTNLAEYLEKGIVK"
     aSDomain        18011..19018
                     /aSDomain="TIGR01472"
                     /aSTool="tigrfam"
                     /description="gmd: GDP-mannose 4,6-dehydratase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_184_0007"
                     /evalue="2.90E-154"
                     /identifier="TIGR01472"
                     /label="ctg1_184"
                     /locus_tag="ctg1_184"
                     /protein_end="339"
                     /protein_start="3"
                     /score="511.3"
                     /tool="antismash"
                     /translation="KTALITGITGQDGSYLAEFLLEKGYEVHGTIRRSSVDYRERIAHL
                     ESHPHFHLHYADLSDSMSILGVVGQIRPTEIYNLAAQSHVQVSFDSPEFTADVDAVGVL
                     RVLEAVRQLGLTNSCRIYQASTSELYGKVEEVPQNENTPFHPYSPYAVAKQYGFWIVRE
                     YRDAYNMFCCSGILFNHESERRGETFVTRKITLAAARIKQGKQDKLLLGNLSSLRDWGY
                     AKDYVECMWLILQHDKPEDFVIATGAQHSVREFCYYAFKRVGIELEFKGEGIDEKGIDK
                     ATGKVLVEVSPDFYRPTDVVNLWGDPTKAKAELGWNPDKTSFEELVNLMVDSDMA"
     PFAM_domain     18020..19000
                     /aSDomain="GDP_Man_Dehyd"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16363.7"
                     /description="GDP-mannose 4,6 dehydratase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_184_0039"
                     /evalue="5.10E-141"
                     /label="ctg1_184"
                     /locus_tag="ctg1_184"
                     /protein_end="333"
                     /protein_start="6"
                     /score="470.0"
                     /tool="antismash"
                     /translation="LITGITGQDGSYLAEFLLEKGYEVHGTIRRSSVDYRERIAHLESH
                     PHFHLHYADLSDSMSILGVVGQIRPTEIYNLAAQSHVQVSFDSPEFTADVDAVGVLRVL
                     EAVRQLGLTNSCRIYQASTSELYGKVEEVPQNENTPFHPYSPYAVAKQYGFWIVREYRD
                     AYNMFCCSGILFNHESERRGETFVTRKITLAAARIKQGKQDKLLLGNLSSLRDWGYAKD
                     YVECMWLILQHDKPEDFVIATGAQHSVREFCYYAFKRVGIELEFKGEGIDEKGIDKATG
                     KVLVEVSPDFYRPTDVVNLWGDPTKAKAELGWNPDKTSFEELVNLM"
ORIGIN
        1 gtcttaattt gaagttgaat tctccggata ttaggcaaga atatagctat aaatgaaggc
       61 ttattcttgc ttgtttttgt taaatttctt gatagtctgg gatatcgcct aaatataaat
      121 atttttgata gtcataatcc attttacaac aataatgctg aatgccgttt gagacgatga
      181 gatagtctac atgaagaagc atattatagg ttgtaatttg atcgaacact ttttgagtaa
      241 tggcgatatg aggtgccttg tattctatga tgatacgtgg tttgagttct cttgaataaa
      301 gaactgtgtc agctcgaaga gttttattgc ctatcttaag tcttacttca tttgccaaaa
      361 gggtggcggg gtatcctttg tgattaatca aaaaatgaac gaagtgttgg cgtacccatt
      421 cttctggagt aagggcaaca tacttacgac gtaaaatgtc gaaaatcgtt ggtttggtag
      481 gcgttccgga taactttatt tcgtaatcgg gtaggtttaa tggaatcatt ttattatttt
      541 tgcagataaa gaacaggttg atgaaaaaga cttcctttta ggataagtct ttgtttcttg
      601 ttttctgcaa agataaacaa taaaaaataa aatagagcga aatgcctgaa aagaaaaata
      661 caggaacatc gtatgaaacg ataatgcgtg acttaaaagc acgtcatttt tcacctatat
      721 atatattaat gggtgacgaa tcatattata ttgataagat ttctgattat attgctgaac
      781 atgtattgag gccggaagaa cgtgatttta atcaaaccgt agtgttcggc tcagatatct
      841 cagcctcaca aatcgtggat tcggccaaag cctttccaat gatggccgaa aaacgggttg
      901 tgatagtaaa agaagcacag aatttgaaag gtacagagcc tttagtgaag tatttcaagc
      961 agccggtggt ttccacagtt cttgtccttt gtcacaagaa tggaagcatt gataaaagaa
     1021 agaagattat tccagcagca caggtaggtg gtgcggttat ttttgagagt aagaagcttt
     1081 atgagcgcga attgccgggt tttataacat cttatttcat gcaacatgag attactatag
     1141 agcaaaaggc agcccaaatg attgcagatc atgttggggc cgacttacat agattaactt
     1201 ctgagcttga taagatttta atttcttttt ctgaggttga tagaatggta actccggaaa
     1261 ttgtagaaaa ggaaattggg gttagcaaag attttaatgc ttttgaatta cgaagtgcta
     1321 ttattcaaag agacgtctat aaggctaatt taattacgaa atattttgac aataatccca
     1381 aggcaggttc cttgttttct tttctcccaa tgctcttttc ttactttgaa aatttgatga
     1441 ttgcatttta ttcaccaaac cgaagtaatg aaaatgcgct tgtacaattt ttggaattac
     1501 gaaatggatg ggctgcaaaa gactacctta ctgggctgcg aaattactcg ggaatgaaaa
     1561 cgatgcagat aatttcaaaa ataagagaaa tagatgccaa aagtaagggg ttagataatc
     1621 caaatacagc ttcaagtgag ttaatgaagg aacttatttt cttcattttg cattaaatgt
     1681 ggctttttta atgctatttt tttctagatt gagtgctctt gtagagcact ttttttatgg
     1741 taatctccga taaataaacg tttaccatag tttttccccc tctaaaactc gcgtattttc
     1801 agcaaagaaa tcccttatca agaatatgtg aattatgtta ttttttatcg atttagcaca
     1861 ctatgatttt gagattagtt tttattaacg ttttgtattc tgaaacttcg gaaacaaaaa
     1921 ccaaaagccc tgaatattat tttagatatg taaacgtaga atgctcgttt ataaataatt
     1981 cttttttatc agaataaaga tnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntaaattt aatatacgaa tgttgtatat
     2221 gttgtttttt tattttactt ttgtaaaatc aataaaaatc gggtattata ctctaattaa
     2281 atataaatgt ttatgaagga tagaataaaa acaatcatgg aaagtcagca tatgactcag
     2341 caaacctttg cacaattcat acaaatatct cctgcatcat tgagtagtat ttttaatgga
     2401 agaactaaac caacattgac cgttgttgag gctattcgtt caaaaattcc atctttatca
     2461 cttgaatggt tgatgtttgg tgtaggtcca atgtataata acgataaggc gaagtctaat
     2521 ttggaggttg tagaaggaac atttgctgct aaagagggct tgaatcattt tggtgagcaa
     2581 acaaaatctc ctactccctc actttttgat caagaccaag aaagaattca gaatataggt
     2641 aatacgctta ttgataataa agaaaaaacg gttaaaataa ttgacaagcc gcaacgcaag
     2701 atttctgaga taagaatctt ttatgatgat agaacttggg aaacttttgt cccacagaaa
     2761 agttagctat tggttagaat gttttttttt cttatatttg catcaaccaa attgcaaaag
     2821 caaatatgaa gaaattcgtt caagatttga ctgtcaaatc tgtagagatt cttagttcta
     2881 agcatgtgct attgaaactt acagcagaag aatcactacc accaacaatt cccggccagt
     2941 ttgttgaagt tcgggttgac aattcaccct ctacttttct tcggcgtcca atttcaataa
     3001 acttagtaga ctatcagcaa aatgagctgt ggttattgat agctatgata ggtgatggta
     3061 ctcaacaatt gggtaaactt aaggttggag atactttgaa ttgtttgtat cccctaggta
     3121 atgggtttac acttcccaac gattcaagtg aaaaaatatt attaattggc ggtggtgtgg
     3181 gtattgctcc acttctttat ttgggacatg agattaaggc taataaagga aaacccacat
     3241 tcattttggg tgctaggaca aagaatgaat tgttagagtt ggacttattc caacaacttg
     3301 gacgtgtttt tattacaaca gaagatggaa gtatgggaga aaaaggcttc gtaactaatc
     3361 attcgattct ccaaaaagaa aagttttcaa gtatttctac ttgtggtcct aagccaatga
     3421 tgatgagtgt tgcacaatat gcatatgcga atgatataca atgtgaagtc tcgctagaga
     3481 ataaaatggc ttgcggttta ggggcatgtc tgtgttgtgt agagaagact gttgatggaa
     3541 atatatgtat atgtaaagaa ggaccggtgt taaatattaa gaaattatta tggcagattt
     3601 aaatgtaaaa ataagcaatc ttcaatttaa gaatcccgta atgacagctt ctggtacttt
     3661 cggttacggg ttggagtttg cggatttagt gccattacat gagattggcg gcataatagt
     3721 aaaaggtact actttacatt cgcgtgaggg caatgacagt ccacgtatgg tggagactgc
     3781 aagtggaatg ctgaattgcg ttgggcttca aaataagggt gttgactatt tttgcaagca
     3841 tatctatcca caaatcaggg atattgatac gaatataata gtcaatgtaa gtggagacag
     3901 tgcggagacc tatgccgaat gtgcccggcg aatcaatgaa ttggacgcgg ttcctgcgat
     3961 agaattgaat atcagttgcc ctaatgtcaa agaaggcggt atggcatttg gtgtatcatg
     4021 tgccggtgcg gcgggtattg tcaaagcggt tagggctgtt tatcagaaaa ctttaattgt
     4081 caaactctct ccaaatgtga cggatattgt atctatagcc cgtgcatgtg aagaggaggg
     4141 agcagatgcc gtttcgctta ttaatacatt gatggggatg gccattgata tagaaaagcg
     4201 cgaacctcta ttgagtatcc gcaccggagg cttgagtggt ccggctatca agcccgttgc
     4261 cctgcgtatg gtttatgatg ttgctcatgc tgtcaaaatt cctgttgtag ggcttggtgg
     4321 tattagcagt acggaggatg ccattgagtt tatgatgtgt ggtgcgaccg caattgagat
     4381 aggaacagcc aattttattg atcctacgat aacaaaaaag gtgaaagatg gaataagcag
     4441 ttggcttgat gcacatggct gtagaagtat ccaagagatt atcggagtcg tttgatttca
     4501 atcatacctt ttgttttaac gtgagttgga tatcggcctt agagcgagaa agcaaaaaac
     4561 aataaattct gcgtttcgtt cgcgagtgac aagtaaaaaa tagcaaattt tgtgtttcgc
     4621 gcgtgtgcga cgacatagaa aataggaaaa agagctttaa aaatctcttc gtctatcgaa
     4681 ctcacattgt tttattgttt atgttttcgg caaaaagtac tatctttgca aagcgtttaa
     4741 tctatttgtt ttatttatcc attatggaga agtctcttaa taaatacatt gttgcttcat
     4801 ataaattgta tgatgtgaca gagggcaaaa aagaattggt agaagaaact tcggccgatc
     4861 gtccttttgt tttcttgagt ggattcggtg ttacacttcc tgcttttgaa gatgcgttgg
     4921 ttaatctggg caaaggagaa tgtttcgatt tctcgctaac ggcagaacag gcttatggtg
     4981 cgtattatca agaacgtgtg attgagcttg acaaatctgt ctttaaggtt gatggcaagt
     5041 tcgatgaagc gcacattgtt gtcggggcaa tcgtaccact tcagaatgaa gatggaaatc
     5101 gctttaatgg tcgcatactc actgtcacgg cggataaggt gaaggttgat ttgaaccatc
     5161 ctttcgccgg caagaaactt aattttgtcg gaaaggtcat agagagccac gaagctgaca
     5221 gtgaagaaat aaccgatttt gtgaacatgc tgaatggaga aagcggctgc ggtggttgta
     5281 gcggaagatg tggtggtgga aactgcgaag gtggttgtgg ttgccattga tgtaaaatag
     5341 tatgagatat ggtgcgaaat agttttggta atatatttgt acttacgacc tttggcgaaa
     5401 gtcatggagt tgctataggg ggcgtcattg acggaatgcc agctggtatt gagatcgatt
     5461 ttgattttat tcaaaatgag ctgaaacgcc gtcgcccggg gcaaagcaaa ataactacga
     5521 gtcgatcgga accggacaaa gttgaattct tcagtggtgt gtttgaaggt aaatctacgg
     5581 gggccccgat tggttttgcc gtctataata ccgatcaaca ttctaaggat tacgacaata
     5641 tgcgtgcgct atttcgtcct tctcatgcag attttactta ctacaagaaa tatggtgagc
     5701 gtgattatcg gggaggagga cgctcttccg ctcgtgtgac aatagcacgt tgcgtaggtg
     5761 gtgctttggc taaattggtg ttgaggaagc tacatattga cattaaagct tatacctcgc
     5821 aagtgggaag tatcatttta gagaatgatt attataaata tgatttgaat actatagagg
     5881 ataacattgt tcgttgtccg gaccaacgga aagctacaga aatggcagaa ctcattgaac
     5941 aggtgaaaaa cgaaggagac acgattggtg gtgtcgtgag ttgtgtcata aaaggctgcc
     6001 cggtgggact tggtgaaccc gagttcggga aacttcatgc acagttggga gcagcaatgc
     6061 tcagtattaa cgccgcgaaa ggttttgaat acggtatggg atttgccgga gtggggaaac
     6121 gtggaagtga acaaaatgat gtcttttatt ctcaaaaagg gaatatctcc acagtcacaa
     6181 atcatagtgg aggtgttcaa ggcggcatca gtaatgggca ggatatattc ttcagagttg
     6241 catttaagcc tgttgctacg cttttaatgc cacaagaaac ggtagatgag catggagatg
     6301 ctacttcttt tcatgcacat ggacgccacg acccctgtgt gctcccgaga gctgtcccta
     6361 ttgtcgaggc aatggctgca atggtggtac tggataacta ccttctcaac ttgacaataa
     6421 aagtatgaaa tcggcatata ggcttttatg atgtaacgtg agttcgatat attcccgggg
     6481 aacttgcaga agtcactctc acgatggaga gtgcagctcg gggtaaaaga acccacccga
     6541 tagcttctac ggcatcggac gacagctcct tttatcattc gagccctcgg atgacagttc
     6601 ctttttactt ttttatcatc cgagccctcg gaaaacagtt taatctttct ttttcttcca
     6661 tccgaggcct cggatagcat ttcccgttaa ttaatttcac atccgaggcc tcggatagta
     6721 tttcctgtta attagttttg catctgaggc ctcggatagt gttttctgtt aattaatttc
     6781 acatctaagg cctcggatag tatttcctgt taattaattt cacatctgag gcctcggata
     6841 actgttcttt ttccatttag cttccatctg agccgtcgga cgagtgtccc ttttttgttt
     6901 tccgctaatc cgatgcttca gagacgcagt ttttctccat ggggcttata tcgaacgcac
     6961 atagggcaga gcgcagcacg aacttcctca tcatgaaaag cgcaagtatg gtgagaagac
     7021 caagggaaac attgaacttc gtaatatcga agccggagtt ttacaggtac tattcgtgat
     7081 attgcacgtg atgtgggaga ctttacttac agaaatcagc agactccagt tttgtaaaaa
     7141 agataaaaag aattgcacgt tacatataaa agttgtatat ttgcctaccg taatagagat
     7201 tagcacttaa tgagacaact gaaaatcaca aaatcaatta ctaatcgaga aacggcatcg
     7261 ctcgataaat acttgcagga aatagggcat gaagaactga tttctgttga ggaagaagtt
     7321 gaacttgcac aacgaattcg gagaggagac cgtcaggcat tagagaaatt gacgagagct
     7381 aatttgagat ttgtggtttc agtcgcaaag cagtatcaga atcaaggatt aagtttggct
     7441 gatttaataa acgagggtaa tctcggtctt atcaaagctg ctgaaaaatt tgatgaaaca
     7501 cgtggcttca agtttatatc ctatgcagtt tggtggattc ggcagagtat acttcaggca
     7561 atagcagaac agagtagaat tgtaagattg ccattaaatc aggttgggtc cgtaaacaaa
     7621 ataaagcgtg cactcaataa gttcgagcaa gaaaatgagt ggtatcccag tatagaggaa
     7681 atagcgaaga aggtggatat tccggaagaa aagattgcag atgccattaa aatgaatgga
     7741 cggcaaatct ctgtcgatgc tccctttaca gatggtgatg attgtacttt tttggatatc
     7801 atgcctaata gtgatgcgct tatggcagat aatgtcttgg ttagagagtc tcttcaagat
     7861 gaaatttcga atgcactcca gacattaagc gaacgcgaac gtaacattat tgaggccttt
     7921 ttcggtatta atcaatcgga actgacatta gaggagatag gagataagtt cggtctgact
     7981 cgtgaacgtg tgcggcagat aaaagagaaa gccattcgta ggttgcggca tcatgcgaag
     8041 agtaagaatc tgaaaacgta tcttggacaa taaaataact ttatatacgt ttgtagtaaa
     8101 taaataacag aaggtaatga gattggaaag attttttttg atagtggttg tgttttccgt
     8161 ttgtaccacg gtatttgccg gaaacaaaaa caaggtgttc ctttgtggtt tcgcagcttc
     8221 atttaatgat tcaaccgttt ttttcaccga tatacaagag gtggattctg ctgtgataga
     8281 taagaatcat ttcctgtttg gtcgcgataa ttattcatat caattgcgtg attacttgac
     8341 ttcgcaaggc tttgagcatg caacttgtgt gacattatgg gcaacggcac gcgatgtcat
     8401 agaaaagaaa tatcagaaac tgagaaataa gtatgcggtt attgctcaga aaagaacaag
     8461 aagaaagaag acagctcctc ttactgtaaa gtatctcaca acagaacagt tccgttatga
     8521 ggccatcgtt cctgagggga ataccgtctc tgcaacaaag caatcagccg tgaaaactaa
     8581 gaagacagga aagtaatcgg gcacaatctt ggttttagat actgttatcg taaaacatat
     8641 ggattactat ttcgagattg ccgagcatta tataaaaatc agtcagttgg acggcaatat
     8701 tccgctctta agcctattgc cttcgtttca gccgttttta tgtgatgccg tcagcgacga
     8761 agaattattg ttcagtttta cgatagacaa tcacttaaag gccgttgata aaagtcggcg
     8821 gcatcccatc aggacttttg acaccggaaa cggagatact gtcgtagata agctttcgga
     8881 tggcggttat caatacgtcg tcaagaacat caacagggac gcgtgtgctt tattgatatg
     8941 cgataaagac ttcaggacgt gttcgtgtac actcaatgga agtttgaata tgcaaagttt
     9001 cggtcttaac aatgcactca tgctgacgat ggcctttgcg ggtagcaagc gcgacacggt
     9061 gctgatacat gcatctttgg tcaggaataa cgattatggt tatgctttca ttgcaaagag
     9121 cggcacgggc aagagcacgc acgtcagcct ttggctgcgc tttatccctg attgcgattt
     9181 gatgaatgac gacaatccaa ttatccggct catcaatggc acgccatata tctatgggag
     9241 tccgtggagt ggcaaaacac cttgctaccg caaagtaaag gcacgtttag gggctattac
     9301 acagatagca cgcgcccggg agaactccat tgagcgtctt tctgtggtaa atgctttcgc
     9361 tacactcctc ccatcgtgtt cgtcgatgaa gtgggatgcc gatatcttca atcatatttg
     9421 cagcattgta agcgacatca tggcccaaac ccctatatac accttgcact gcagggctga
     9481 ccggcatgct gctgatttgt gtcaccaaac cataaccgca gagtgaagaa ggtttttcca
     9541 aatgaacagc tgatacccga ggttatctcg ttaatcgaac aagggcacac cgtgacgctc
     9601 ccgcttcgtg ggttcagcat gcgtccgttc ttggaagaca atcgcgacaa ggcactgttg
     9661 acaaagccgg accggttgaa ggtgggagac cccgttttgg cagaggtgcg cccgaagttc
     9721 tacgtcttgc atcgcatcat tgcaatcgat ggcgagcatg tcgtcctccg tggtgacggc
     9781 aatctggcat gcgagcattg tctgcagaaa gatgtcaagg ccgctgtcat cggcttttac
     9841 aggaagaaac ataactatct agaccggacc gatggtctaa aatggcgcct atattcacgc
     9901 ctttggctct ttctctttcc cgtccgccgc tatctgttgg ccttttaccg acgcgtgtgg
     9961 ataaagtgtt tcggattgat ttaataataa ataaacacgt atgaaaacaa aacaaggatt
    10021 tatacttcgc aacgtttgtg gtgagaacat tattgttgcg gagggcgaga cgaatattga
    10081 tttcagcaat atcatcagta tgaacgaaac gtctgctttc ttatggaaca atattcaagg
    10141 aaaagaattc acacacgacg accttgtcga tttgctgacc gagacgtatc aggttgatgc
    10201 gcaaaaagcg cttgaagatg ttacccgtct cgtcgataac tggaaatcgg caggcattat
    10261 agaataagta ttgctgtccg gtaaacattt tccgcacagc aataaaaatg gcatgtgcat
    10321 ggaaatgcag aatgtttcgc atgagttctt ggcaatgttt atttcactca gaaatgattt
    10381 cagccgtttt acctcgcaat ctcagtcata tcaggcgata aaatggctga gattgtgagg
    10441 taaaatggct gaaatcaagt cgtaatatga ctaagatgga aaagtctttg aaagtcaatc
    10501 aactatatgc attgttgatg atgaattttc tttcaagctt gtcggttacg taactgcatg
    10561 ataagggcat tcaattggtt ttcatcttgt atcagcacct cacgcggttt acttccttgc
    10621 gcagtaccga caatacccat atgttcaagc tgatccatca atcgccctgc acgattgtac
    10681 ccaatggaga agcgacgttg aatcatactg gttgaacctt gctgagaaag aacaattgca
    10741 tgggctgctt cctcgaagta agggtcgagt gaagaaatgt cagttgcccc gtcacctata
    10801 ctaccaccgc tattatcctc gattggttcg ggaagttcca tgggctctat ggggccgggc
    10861 tcttcactga tgtaatcgtt tatatgctcg atttcgggtg tatcgacaaa ggcacattgc
    10921 acgcggacag gctcattgcc attcaagaag aggaggtcgc cccgacctac aagctggttt
    10981 gcgccggaac ggtcaagaat tgtgcgcgaa tctatctggg aactcacacg gaatgccatt
    11041 cttccgggga agttagcttt aatatttcct gtaataatct ttgttgtcgg acgttgtgtt
    11101 gcaatcacca tatggatacc gacagcgcgt gccaactgtg caatacgtgc aatcggaagt
    11161 tctatttcct tgccagctgt catgataaga tcgccgaact catcgatgat gacaacaata
    11221 taaggcatgt agtcgtggcc tttcgtgaga tcaagtttat gattgacgaa tttagcatta
    11281 tattccttga gattctttgc accagccatc ttcaacaaat catagcgatg gtccatgagc
    11341 gcacagagac tgttcaacgt tctgaccact ttggtgacat cggtgataat gggctcttct
    11401 tcattttcag gcagacaggc cataaaatgt cccgaaatct tgtgatagac actgaactcg
    11461 accttctttg ggtctacaag aacgaatttc agttcatttg gatgcttctt atataataat
    11521 gatgtgataa tcgcattcag gccaacagac tttccttgtc ctgtcgcacc ggcaacgagt
    11581 agatggggaa tcttggccaa gtcaaccata aagacctcgt tggtgatggt ttttcccaat
    11641 gccaagggca gttccatctt tgtttctttg aactttttgg agttaagaat actctccatg
    11701 gagacaatct gcggcctttt gttcggtact tcaataccaa tggtcccctt gcccggtata
    11761 ggagcgatga tacgaatacc aagtgccgaa agactcaagg caatatcgtc ctctaagttt
    11821 cgtattttag agatgcgtac accctcggct ggagtaatct catacagtgt aatggtaggg
    11881 ccgacagtag ctttaatctc tctgattgac acaccgaagc tgttaagcac ttcgacaata
    11941 cgggcattgt tggccttgat ttcttccatg tcgacattgg gtttgtcttc ttcgtcatac
    12001 tttttcagaa gctcaagcgt tggtttcttg tacttagtaa aaggctccag agggtctata
    12061 ggcgtactaa ggatatcttc caagttcaca actgcactgc cggctttctc ttcattcttg
    12121 gcaatctcca ctgtcagccg attgtcgttt gccgtctgag gctctgaatt gttcgtaacg
    12181 ctcagcgtgg gagctgcatt tgcaggtaaa gtatctttgt caatatttcc aaagtcggta
    12241 agatccacca caggagcagg aaaatcttcg ggcaacccct gatttatcgt attgctgtct
    12301 tcagtttctt cgttattatc agccgctgca ttgtgttcgg agtcagctgt gtctatctcg
    12361 tgattcgtaa ccgtgaactt gactttagaa gtcagatatt tcaccggatt catcgctttt
    12421 ctaataataa aaatcgtttc tgcgctcaga taagtcaaga aggcaagtgc cgtgaaaagc
    12481 agaattacga ttaatcccgg ggcaccgaca atgttctcta actgctgaac acagaacaat
    12541 ccgtgattgc caccgggatt aaagaacaaa tttcccatga caggagtaag gaacttggca
    12601 aatgttatcg aacaccatat catggtcaac atcataccaa agaaccattt ccacaggttg
    12661 atggtataga tgctcatcag tttcagtccg actaagacaa taaaagctgg aataatgaaa
    12721 gccggcaggc caaaattaac cgacatgagg gtgtaagcca caatggctcc gatggaaccg
    12781 caataatttg taatcgaacg gttagagttt atccattctc catgccttaa actttcaaga
    12841 atactttggt catcctgccc agtagagaag taggagacca tagctatgat tacataaatt
    12901 gcaattaaga ggagtataag tcctaaaagg aaatctgttt tttcattact gaaaatattg
    12961 cgaaagccga ctgcctcacc aatactcttg ggtttgcggt cagatttttt ccttgccatg
    13021 tttatagagt cgatattgta tttcttgcaa aattagtgta aaattccgag aaaaggcgtt
    13081 cttttcgtaa cttttttcta attttgcacg ttggaacaag ccatttataa tgaagaagac
    13141 aatatacagc aagtttgata aaaaaaagat taccaatctc cctatcgttc aatttccggg
    13201 aaggatcatt acaatcgtca gtgagacaga tgccgataag gccgttgatt atctcttatc
    13261 gcgtgatatc ttaggcgtag ataccgaaac ccggccgacc tttcataagg gagaacagca
    13321 taaggttgca ttattgcaag ttgcatcgca tgacacttgt ttcttattcc ggcttaacga
    13381 tataggaatg cctgcctcaa ttataagatt gttagaagac cagaccgtcc caaaaatcgg
    13441 tttgtcatgg catgacgata ttctttcttt acaccgccgc acagagttta caccgggata
    13501 ttttatcgat ttacagaatg tgataggtga gattggtata aaagatctca gtcttcagaa
    13561 gctttatgcc aatctctttc atcaaaagat aagtaaacga caacggctga caaattggga
    13621 agcagatata ttgaatgaca aacagaagca atatgctgcc acggacgctt ggagttgtat
    13681 taaactctat gaagaggtta agcgactgca tgagacaaaa gattatgagt tgatcgttcc
    13741 gctggaggtt actgaaaaca acaatgacta tgctgtctga caagttttgt taatcatcga
    13801 aatatttgaa cttatgtata aatctgtcta tctcaagaaa gggaaagaag aatcgttgaa
    13861 ccgcttccat ccatggattt tctcaggcgc cattcatcac atggaagaag gcatagaaga
    13921 gggagatatc gtcaatgtat tcactgcgac gaacgatttt attgcggtcg gtcactatca
    13981 gattggctct attgccgtac gcgtgctttc gttttcagaa gaggaaatca atcattcttt
    14041 ttggtgtagt catttggaaa gtgctttgaa aatgcggcaa cgcatcggca ttgcagataa
    14101 tgagaacaac aatacatatc gattggtaca tggcgaaggc gacgctctgc ccggattgat
    14161 tatagattgt tatggtgaaa cgatggtcat gcaggcacac agcgtaggta tgcatgcttc
    14221 ccgcaaggca gtgtgccgtg cattggttga agttatgggt aaccgcatga agcacgttta
    14281 ttacaaaagt gagaccacac ttccattcaa ggccgaactc gaacaagaaa acgattttat
    14341 tcatggcggg acagacaatg atattgccat tgagaacggg ttgaagtttc atgtggactg
    14401 gttacatgga caaaaaacgg gattctttat cgatcaaaga gaaaatcgca gtctgttgga
    14461 gcactatgct aaggacaaaa gcgtactgaa tatgttctgt tatacgggtg gcttctccgt
    14521 ttatgccatg cgtgggcaag ccaagatggt tcattccgtt gatagtagtg ccaaagccat
    14581 agaactgaca aatagaaaca ttgatttgaa tttccccggt gacaaacgtc acgaagcctt
    14641 ttgtgaagat gcattcaagt atttggacaa tacagacaac gccaacaaat atgatttgat
    14701 tgttctcgat cctccggcat ttgccaaaca tcgtaaagca cttcataatg cattgaaagg
    14761 ttacactcgg ttgaatgtga aaggattgca gcgcattaag cagggcggta tcttgtttac
    14821 gttcagctgt tcgcagatag tttcaaaaga aaacttccgt aatgctgtgt ttacagctgc
    14881 ggcgcaggca gggcgtaagg tgaggatttt gcatcaactt catcaacctg cagaccatcc
    14941 catcaacatt taccatccgg agggagaata cttgaaaggc ttggtgcttt atgttgagta
    15001 gtttcgcata tggtgtcaaa gcgtttatcg ataggaaccg tttgttgaag accgatggtt
    15061 tctatctgct tgctttaagc ggaggctgtg acagcgtggc tctgctccgt gtgatgatag
    15121 aactcggcta tcgtttcgct gccgtccact gcaattttca attgcgtgga gaggaatctc
    15181 agcgtgatga attgttttgc gagcaacttt gcctcgctca aaaggtccca ttccatcgtg
    15241 tccatttcga tacaaaagcc tatgccaagc ttcatcgtgt cagcattgag atggccgcac
    15301 gcgaactgcg ctatcgttat tttgaacaat tgagaaaaga cttgggagca gatgccattc
    15361 ttgtggccca ccataacgat gattccgtcg aaactttttt gcttaatctg atacgtggaa
    15421 ccggaattca cgggctattg ggaataaaac cgaaaaacgg tttcatcgtt cggccgttgt
    15481 tacccatcgg ccgttccgac atagaagcat atttatccgg tatcgggcaa gcgttcgtga
    15541 cagactgcag caaccaaatt gccaatgtca agcggaatat gatcaggctg aaagtgttac
    15601 cgctgctccg cgaaattaat ccttccgtgt cagacagcat tacttcgaca gccaaacgat
    15661 tggggcttgt ggcgcagata ttcgataaag ctatggctga aagtattgcg gcagtaacct
    15721 ctcatcaagg ggcggacaag tgtgtcatag acattcggca gctgaaaaaa gaaacggcac
    15781 cggagtacac gttgtattcc attctcaaaa aatatgcgtt ttcatcggcc cagatagaaa
    15841 gtattgcatg ctcactcgat gcgccttcgg ggagaaaatg gttatcgaaa tcgcacgaac
    15901 tggttgtgag cagaggacaa ctgattgtcg ttcctctttt gcaggacgcg aaccgttccc
    15961 tgagtctgcc cgaaccgggg cgctatgtct gggatgatgt gatgaagttt gatgtcacct
    16021 tgtgtgacat ttcgtcggat ttttccccga gtcgtagtaa aaacatcgtt acattggctg
    16081 ctgacagcgt ccgtttcccg ctgcttgtcc gtcatgtcca caagggcgat agattccgcc
    16141 cgttgggaat gaaggggagt aagctcgtca acgacctgct gacagacctg aaactttcat
    16201 tagacgagaa acaacgtcag ctggttgtcg tcgatgcagc cgataagatt atttgggtcg
    16261 tggggagaag gatagatgac agcgtcagcg taacatccga aacgacagaa atactacgct
    16321 tgcaaattct ttaaaagcct gcttttaact ctgccgaaag ccaagggtaa aatacatatc
    16381 agcgggagcc ccgccggaag tcaaaactca aaagacgtat cagcgaaagt tccgccaaga
    16441 gtaaaatttt aaggaaagta tcggcggaag ttccgccggg agtcaaatgt taagatatgt
    16501 attggcggaa gttccgccga agataaaata ttaagaaatg tatctgcgga aggttccccc
    16561 ggctctttcc aaatagaagt gcaaaatctt ggtggtgttt gacactatgc aaaacaccac
    16621 ggggcttgcc ttgcggctgg ggggtgaagc ccccaaagag cccggcggaa gacttaagca
    16681 atgcaaaaaa ggaggagaac gcgtccgctt ccaatatgga tgtcaactct tgctatcacc
    16741 cattaaaaat tgggcttctg tcttgaatgt ttagaattct gccaacatat agccaacggt
    16801 agcagtttac aaaaggagaa tcaacaaggt tctcgatttt tatgcccgag ggcaatttca
    16861 ttccttatca tttgcccatg tatggaaaat tatgtaactt tgggcctgat taaaaattac
    16921 agagttatgg ctgataaaaa taatcattta gttatcatgg ccggcggtgt cggcagtcgc
    16981 ttctggccga tgagcacggc agcacgcccc aagcagttta ttgacgtgct gggggtgggg
    17041 cgttccttgc tgcagttgac ctacgaccgt ttcaaaggaa tttgcctacc cgagaacgta
    17101 tgggtcgtga ccaacaaaga ctacgccgag agctgtcggg aacaattgcc cgatgttccg
    17161 gcggagaaca tactgctgga gccgtgccgt cgcaacacgg caccctgcat tgcctatgtc
    17221 agctggcgta tcaagtcgaa agacccgagg gcaaacgtcg tcgtcacacc aagcgaccat
    17281 atcgttaccg acacggcaga gttcaggcgt gttgtcgctt cgtgcctgaa gttcgcgggc
    17341 gagactgatg ctatcgtcac cttgggcatg aaacccaccc gccccgaaac aggttacggc
    17401 tatattcagg ccgacctctc caccgcttcg cctcgcaata aggagatttt ccgcgtggat
    17461 tcgttccgcg agaagcccga tgccgatacg gctacgaaat atatccggca gaacaattat
    17521 ttctggaatg caggcatttt catctggagc gttggcacca tcgtcaacgc gtttagggtc
    17581 tatcagcccg ccatctccaa agtcttcgag ggaatggaac gcatttacgg gacggctgaa
    17641 gaacagtcgc tcattgatga acgctacccc gaatgcgaga gcatttctgt ggactatgcc
    17701 atcatggaga aagccgagga aatcttcgtg tgtccggctg acttcggttg gagcgacctc
    17761 ggcacatggg gcagtctgct tgccgaaagc cggaaagacc tctacggtaa cagtctcatc
    17821 ggcgacaata ttacattgtt tgactcccac aactgcattg tccacaccat gcaggagaag
    17881 caagtggtcg tgcaagggct cgacggctac atcgttgccg agaacgatgg ccggctattg
    17941 atttgtaaac tatccgaaga acagcgtatc aagcagttct ccgaaaacaa ataaaagaat
    18001 aatggaaaga aaaacagcac ttatcaccgg tatcaccgga caggacggtt catatttggc
    18061 cgagtttctc ttggagaaag gctacgaggt gcatggcacc atacgccgct cctccgtcga
    18121 ctaccgcgag cgcattgccc atttggagag ccatcctcat tttcatttgc actacgctga
    18181 cttgagcgac tcgatgagca ttctgggcgt cgtcggtcaa atccgaccga cagaaatcta
    18241 taacctcgcg gcgcagagcc atgtgcaggt gagtttcgac tcgcccgaat tcacggccga
    18301 cgtggatgcc gtcggtgtgc tacgcgtgtt ggaagccgtt cgccaattag gtctcaccaa
    18361 ttcctgccgc atctatcagg ccagcacgtc agaactctac ggcaaggtgg aggaagtgcc
    18421 gcagaacgaa aacacgcctt tccaccccta cagcccatat gcagtggcca agcaatatgg
    18481 tttttggatc gtgcgcgaat accgtgatgc ctataacatg ttctgctgct cgggcattct
    18541 gttcaatcac gagagcgaac gccgtggtga aaccttcgtc acgcgaaaga ttacactggc
    18601 tgccgcacgc atcaagcagg gcaaacaaga taaactcttg ctgggcaacc tgagttcact
    18661 gcgcgactgg ggctatgcca aggactacgt ggagtgcatg tggctcatct tgcagcacga
    18721 caaacctgaa gatttcgtca tcgctacggg cgcacaacac agtgtgcgcg agttctgtta
    18781 ctatgctttc aagcgtgtgg gcatcgaact ggagttcaag ggcgagggca tcgacgagaa
    18841 aggtattgac aaggccacgg gaaaagtgct cgttgaagtc agtcccgact tctatcgccc
    18901 gacggacgtc gtcaacctat ggggcgaccc caccaaggcc aaggccgaat tgggctggaa
    18961 tcccgacaaa acgagcttcg aggaactcgt caacctcatg gtcgatagcg acatggccaa
    19021 agtggcttcg gagggcgcag ccgagaaggt acgtaccaat ttggccgaat accttgaaaa
    19081 aggcatcgtt aaatagcctt tttcccgttt tatatttcac gcatatccgc tttggaatat
    19141 gcgtgaaatc tttttatatt gctgtccggt agacctcttt cgcatataga accacaagct
    19201 tgtcaatcgt aaaccacaag tttatgaccc gtaaatgtca agatcttgaa agcatatcgg
    19261 gcagatgttg ataatcaatg ccttactatc agttcataat atcagccatt ttagccttca
    19321 atatcagcca tttcaccgcg taagatgggc catattgcgc ggtgaaatgg gccattttgt
    19381 cgggcgatat gagacggact tgttttctga atgaaccaaa aaggataacc atttggacga
    19441 tagcgcacac gaagcgccta caacgtaagg ataagacagg cccaatcgcc ctcttgcttc
    19501 cgtccgaatt cttccaatcc aagttgtcgt gcatgcttca gaagcaaggg aatgtcggcc
    19561 gcatagaagc cgctgagtat cagcaagccg cctttggcca tgacattctt gaaagtttcc
    19621 aaatcgttta agagtatgtt gcggttgatg ttggccatga caacgtcgaa aaccccgctg
    19681 atatggttca gtacattggc atcaccatgg tacacctcca tattttctac gccgttgagt
    19741 gaggcattat gccgggaatt ctccacgctc cactcgtcta tatcatatcc gataacacac
    19801 tttgctccat gcttcgcggc gacaatcccc aatattccgg tgccacaacc acagtcgatc
    19861 acacgcttac ctttcaggtt ctggtggagc agggtagaga ctatcaacct cgttgtctcg
    19921 tgtgttccgg tcccaaaggc caatcttgcg tcgatgaaaa catgctctgt cttgccggtt
    19981 gtggcgggaa caggcttctt ggcatcgcaa atcaagagtc ttccctcaat gtcgataggt
    20041 tcgaagccct gtgcctccca ttcttggttc cagtctttat catcggcatt tctcactata
    20101 taagtgatgt gaacgcccgg tataataaaa tgttcgatag ccttcttcat cacgtcttca
    20161 ttccaattct ccgtttgggc gaatgctttg agtccgtttt cagtgtcttc gaacgattca
    20221 caaccggctt ctccggctgc atctgccagc aaagcgcgtg cgtcatc
//
