LOCUS       NZ_CP068161.1          12553 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP068161.1 Corynebacterium propinquum strain FDAARGOS_1112
            chromosome, complete genome.
ACCESSION   NZ_CP068161
VERSION     NZ_CP068161.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:14:24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 882060
            Orig. end    :: 894613
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12553
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[887060:889613](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7553
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
     cand_cluster    1..12553
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12553
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     CDS             complement(739..1812)
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 229.7; E-value:
                     6.3e-70)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_818"
                     /transl_table=11
                     /translation="MSSFVPHSVLHASNRRGLIARLAAIISSLTLVFGLAACAESGENQ
                     EKAEANPGDARTIEHALGVAEIEGNPERVITLGQGSTETALALGVVPVAVESYEWGADE
                     SGYLPWVNEELEELGVTDDEKPELIAGGEELSAEKIAALEPDLILAPWSGLTQEQYDQI
                     SKIAPTVAYEEEPWVITWDEQIKTVAKALGKEDQAQGLIDGINAEFADAKEESYGDHTF
                     SFIYNAGVGNYGIFLPTEQRVQFVSKLGLQVDPVVEEFRDSVVAGTDSATVSAENLDKL
                     NDSDLIFTFYTDEDSRKELHADATYSSIAAIAKGAEVAPTDQSFVTGSSMINPLTVPWA
                     IDRYKEKIDEALVKAGK"
     PFAM_domain     complement(868..1593)
                     /aSDomain="Peripla_BP_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01497.20"
                     /description="Periplasmic binding protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_818_0001"
                     /evalue="9.60E-22"
                     /label="ctg1_818"
                     /locus_tag="ctg1_818"
                     /protein_end="315"
                     /protein_start="73"
                     /score="77.7"
                     /tool="antismash"
                     /translation="VITLGQGSTETALALGVVPVAVESYEWGADESGYLPWVNEELEEL
                     GVTDDEKPELIAGGEELSAEKIAALEPDLILAPWSGLTQEQYDQISKIAPTVAYEEEPW
                     VITWDEQIKTVAKALGKEDQAQGLIDGINAEFADAKEESYGDHTFSFIYNAGVGNYGIF
                     LPTEQRVQFVSKLGLQVDPVVEEFRDSVVAGTDSATVSAENLDKLNDSDLIFTFYTDED
                     SRKELHADATYSSIAAIAKG"
     CDS             2055..3593
                     /NRPS_PKS="Domain: Aminotran_5 (160-286). E-value: 3.8e-08.
                     Score: 24.4. Matches aSDomain:
                     nrpspksdomains_ctg1_819_Aminotran_5.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 345.8;
                     E-value: 6e-105)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_819"
                     /transl_table=11
                     /translation="MDSYSRKFAPQAQPGLQFLGDGYSHQHALSSAGQTLNQALAPTFS
                     PSPETFCPNKDLGVDELSAAFNAVEIDTPLGSLDEALKELNDLWVSHAIRYDSPRYLAH
                     LNCPITAAGFAGATISAGLNTAVESWDQGRGAAIIEDQIIKWFAASAGMSTNNATGTFT
                     SGGTQSNLQALYTSREKALNSGSSLDSLRVLCSEEAHYSIARSAHILGLPKEAVITIDC
                     DSDGALKISSLRRTINSLIETDGKHTIACLALTAGTTDLGAIDPIAQATQIAQQHGIYV
                     HVDCAYGGALLLSDKNQKLLSGLHQANSFSLDFHKTFFQPVACSALIYRDLTELEHVTW
                     HSDYLNPETDTRLNLANRSLQTTRRFDALKLWLSLRADGPKALGQAFDRCCEIATDAAE
                     LIHEFPELELLTTPTLSTVLFRFLPSLPGSPSSHTCMRETEVINKINDAIRRQLFNANE
                     LVIASTRRNGKTYLKFTILNPRLTKDDIRYALEKICAAGTDECAKLQSKEEIDD"
     PFAM_domain     2334..3320
                     /aSDomain="Pyridoxal_deC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00282.21"
                     /description="Pyridoxal-dependent decarboxylase conserved
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_819_0002"
                     /evalue="1.30E-47"
                     /label="ctg1_819"
                     /locus_tag="ctg1_819"
                     /protein_end="422"
                     /protein_start="93"
                     /score="162.4"
                     /tool="antismash"
                     /translation="IRYDSPRYLAHLNCPITAAGFAGATISAGLNTAVESWDQGRGAAI
                     IEDQIIKWFAASAGMSTNNATGTFTSGGTQSNLQALYTSREKALNSGSSLDSLRVLCSE
                     EAHYSIARSAHILGLPKEAVITIDCDSDGALKISSLRRTINSLIETDGKHTIACLALTA
                     GTTDLGAIDPIAQATQIAQQHGIYVHVDCAYGGALLLSDKNQKLLSGLHQANSFSLDFH
                     KTFFQPVACSALIYRDLTELEHVTWHSDYLNPETDTRLNLANRSLQTTRRFDALKLWLS
                     LRADGPKALGQAFDRCCEIATDAAELIHEFPELELLTTPTLSTVLFRF"
     aSDomain        2535..2912
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_819_Aminotran_5.1"
                     /evalue="3.80E-08"
                     /label="ctg1_819_Aminotran_5.1"
                     /locus_tag="ctg1_819"
                     /protein_end="286"
                     /protein_start="160"
                     /score="24.4"
                     /tool="antismash"
                     /translation="TFTSGGTQSNLQALYTSREKALNSGSSLDSLRVLCSEEAHYSIAR
                     SAHILGLPKEAVITIDCDSDGALKISSLRRTINSLIETDGKHTIACLALTAGTTDLGAI
                     DPIAQATQIAQQHGIYVHVDCA"
     CDS             3586..5004
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 365.5;
                     E-value: 5.5e-111)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_820"
                     /transl_table=11
                     /translation="MTKKIHEQPSTNITQRVAADEVFDIVGIGIGPFNLGMAALAHPLV
                     QSNELKAIFFDENQGFCWHPGVMFPNSTIQVPFMADLVSLADPTSPWSFLNYLKRQGRI
                     YQFYIRESFYPYRTEYSNYCAWVAGQLSTLQWSSPVTDVHRTKDGLWRVQVGGTNPRAV
                     LAKNLVNGTGTQPYVPTSLQPNLVESRNQTKNIIHSSDFLFHAERLSNSEDIQSLTIVG
                     SGQSAAEIYRHLMEPFAATGRRLNWLTRSPRFFPMEYTALTLELTSTDYVRHFHRLPEA
                     RRDQINRQQRNLYKGISGDLVNDIYDTLYQLSITTPLRGELRPDVTVELFTESDLKSSY
                     ERHINEQAAESQILLKLTNNETGNADIHATDAVILATGYGRPAIPSHLITAAEAGEINT
                     DKQGRLDVNLDFTVNQRRDLYVLNAEEHTHSLNAPDLGMGAWRNSIILNNICGRTVYEV
                     EDSWTFQQFGGENV"
     PFAM_domain     3646..4725
                     /aSDomain="K_oxygenase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13434.8"
                     /description="L-lysine 6-monooxygenase (NADPH-requiring)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_820_0003"
                     /evalue="1.20E-101"
                     /label="ctg1_820"
                     /locus_tag="ctg1_820"
                     /protein_end="380"
                     /protein_start="20"
                     /score="340.4"
                     /tool="antismash"
                     /translation="EVFDIVGIGIGPFNLGMAALAHPLVQSNELKAIFFDENQGFCWHP
                     GVMFPNSTIQVPFMADLVSLADPTSPWSFLNYLKRQGRIYQFYIRESFYPYRTEYSNYC
                     AWVAGQLSTLQWSSPVTDVHRTKDGLWRVQVGGTNPRAVLAKNLVNGTGTQPYVPTSLQ
                     PNLVESRNQTKNIIHSSDFLFHAERLSNSEDIQSLTIVGSGQSAAEIYRHLMEPFAATG
                     RRLNWLTRSPRFFPMEYTALTLELTSTDYVRHFHRLPEARRDQINRQQRNLYKGISGDL
                     VNDIYDTLYQLSITTPLRGELRPDVTVELFTESDLKSSYERHINEQAAESQILLKLTNN
                     ETGNADIHATDAVILATGYG"
     CDS             5001..7553
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     72.4; E-value: 8.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_821"
                     /sec_met_domain="IucA_IucC (E-value: 8.2e-61, bitscore:
                     202.7, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKSQQSCHPISLTPGAMHTSLGTVNIRPVQPTKDAKTLHTWVTH
                     PRAHFWGALDASEQEILAEYRRIETSNAEQAWLLYLDGNPIALSETYDPKHVVLNTCSE
                     FTLHEGDIGMHILVSPPIGKSIHGLTDNIFSALVRWIFSHGEVNRIVVEPDVSNLGIHR
                     KNARTGFTQPGLTTTLTMSGKPKTALIQYCTRPDFLGSPNAPLSYPIAPTPWELVKPTD
                     SSSPVTLGIGHLAKTADAAHRELFAKALREFTHERLISPRKIKESADETESNDGNHSGW
                     RSYQVSWGSRKLIFRAREHRLLHLSVDPLSIHDPADLTWTPDIITGIADAAEQLGIAES
                     SRETYLEEISATFAARARTLALPRPTSTELADATRDPAELFQTIESAMVIGHPGFLANS
                     GRGGMGETQLRAFSPELSSTTDLVWCAVDKNYAHLATIEYERAQESGSSHSSNEAILTL
                     VPDFKDRCRLAGLSPDDYIPLPVHPWQWEQRFTTTFSADLAAGRIVPLGREGEAYRPQQ
                     SLRTFFNTSTPAAPYVKTAVAVRNMGFTRGLSAHYMESTPRVNLWLLNLIGDDPEFFQS
                     GIGFLPEIASVGYTGSVYHRVTNDGSHTKMTAALWRQSPFSPETTPALDDGDTLSTLAG
                     ILHSDDEGLPLISAWINQSGLSAVDWINQLLTLYVRPLIHALVRYGIVFMPHTENVILR
                     LNQNKPVGIYHKDLGEEIAVVSNETPVPSGLERLRARCGSDSPEDLSQQALSIHTDVID
                     GVLRHLAALLDDHAILEEDVFWEQLRHVASVYAKDHPELTTGDSRQARLWQALLAPRFR
                     HSTLNRLQLRNPHTMVTLGDQDSSLIYAGELENPLHGV"
     PFAM_domain     5094..5516
                     /aSDomain="Acetyltransf_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13523.8"
                     /description="Acetyltransferase (GNAT) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_821_0004"
                     /evalue="8.10E-35"
                     /label="ctg1_821"
                     /locus_tag="ctg1_821"
                     /protein_end="172"
                     /protein_start="31"
                     /score="119.7"
                     /tool="antismash"
                     /translation="PTKDAKTLHTWVTHPRAHFWGALDASEQEILAEYRRIETSNAEQA
                     WLLYLDGNPIALSETYDPKHVVLNTCSEFTLHEGDIGMHILVSPPIGKSIHGLTDNIFS
                     ALVRWIFSHGEVNRIVVEPDVSNLGIHRKNARTGFTQ"
     PFAM_domain     6141..6911
                     /aSDomain="IucA_IucC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04183.14"
                     /description="IucA / IucC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_821_0005"
                     /evalue="2.40E-62"
                     /label="ctg1_821"
                     /locus_tag="ctg1_821"
                     /protein_end="637"
                     /protein_start="380"
                     /score="210.7"
                     /tool="antismash"
                     /translation="FQTIESAMVIGHPGFLANSGRGGMGETQLRAFSPELSSTTDLVWC
                     AVDKNYAHLATIEYERAQESGSSHSSNEAILTLVPDFKDRCRLAGLSPDDYIPLPVHPW
                     QWEQRFTTTFSADLAAGRIVPLGREGEAYRPQQSLRTFFNTSTPAAPYVKTAVAVRNMG
                     FTRGLSAHYMESTPRVNLWLLNLIGDDPEFFQSGIGFLPEIASVGYTGSVYHRVTNDGS
                     HTKMTAALWRQSPFSPETTPALDDGDTLSTLAGIL"
     PFAM_domain     6978..7475
                     /aSDomain="FhuF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06276.14"
                     /description="Ferric iron reductase FhuF-like transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_821_0006"
                     /evalue="8.10E-26"
                     /label="ctg1_821"
                     /locus_tag="ctg1_821"
                     /protein_end="825"
                     /protein_start="659"
                     /score="91.5"
                     /tool="antismash"
                     /translation="DWINQLLTLYVRPLIHALVRYGIVFMPHTENVILRLNQNKPVGIY
                     HKDLGEEIAVVSNETPVPSGLERLRARCGSDSPEDLSQQALSIHTDVIDGVLRHLAALL
                     DDHAILEEDVFWEQLRHVASVYAKDHPELTTGDSRQARLWQALLAPRFRHSTLNRLQLR
                     NPH"
     CDS             7664..8725
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 330.3; E-value: 1.8e-100)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_822"
                     /transl_table=11
                     /translation="MRKNSREYTRSSRSLRTRRITGLLALALLLAAALLASLLFGARPI
                     AFADAVQALINLPSLLDEPQSGSADARVIADLRWPRTLIGLFVGAALGVAGALIQGHTR
                     NPLADPGLLGVSAGAAFAVVLGFFAFGLTSALSTSVVAFCGAVLATALVFGLASLGGGQ
                     INPLTLILGGAALTAVLHSMTTALTLIDDNSLDRMRFWSVGALSGRDLSIFWGTAPFIA
                     VGLIVALATAPTLNLLNLGDDAASALGVNTYRARLAGMVVIALLAGAATAAAGPIGFIG
                     LVVPHIARSLCGPDYRWILPYSALTGASLLLLSDILGRLIARPGELQVGIVLAFVGAPF
                     FMYLIYRRKVVAL"
     PFAM_domain     7748..8704
                     /aSDomain="FecCD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01032.20"
                     /description="FecCD transport family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_822_0007"
                     /evalue="2.10E-93"
                     /label="ctg1_822"
                     /locus_tag="ctg1_822"
                     /protein_end="347"
                     /protein_start="28"
                     /score="312.9"
                     /tool="antismash"
                     /translation="LLAAALLASLLFGARPIAFADAVQALINLPSLLDEPQSGSADARV
                     IADLRWPRTLIGLFVGAALGVAGALIQGHTRNPLADPGLLGVSAGAAFAVVLGFFAFGL
                     TSALSTSVVAFCGAVLATALVFGLASLGGGQINPLTLILGGAALTAVLHSMTTALTLID
                     DNSLDRMRFWSVGALSGRDLSIFWGTAPFIAVGLIVALATAPTLNLLNLGDDAASALGV
                     NTYRARLAGMVVIALLAGAATAAAGPIGFIGLVVPHIARSLCGPDYRWILPYSALTGAS
                     LLLLSDILGRLIARPGELQVGIVLAFVGAPFFMYLIYR"
     CDS             8722..9831
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 269.4; E-value: 6.2e-82)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_823"
                     /transl_table=11
                     /translation="MTNSPHLLSRPVVPGRPALRKGRISLVWRPWVLFSTIAMICAAVI
                     IFAASIAIGDYPLTVPEVLRIIFLGDGSRIERIAVFDWRMPRALTALTVGFALGLAGAL
                     TQSVTGNPLASPDILGITSGASAAAVTVLTFGGGVGAFAAVSGKVATFGLPLAALAGGL
                     ITGAVVWILSSRGSFDAYRLVLFGIIITALMNAYIGFLMTRAELRDAATAQQWLAGSLN
                     STNWDRAVPVALVILICVPLLAWMAYTLTAAVLGQDLAAALGLRVSRTQLTFLVIAVTL
                     ASIAVAAAGPIGFVAFVAPQLAVRITKLSTPPLVASAFMGAILLLGADLVVRTNIPVDL
                     PVGIVTSAFGGVFLLYLLISSNLKRSRSS"
     PFAM_domain     8851..9798
                     /aSDomain="FecCD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01032.20"
                     /description="FecCD transport family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_823_0008"
                     /evalue="2.20E-77"
                     /label="ctg1_823"
                     /locus_tag="ctg1_823"
                     /protein_end="359"
                     /protein_start="43"
                     /score="260.2"
                     /tool="antismash"
                     /translation="VIIFAASIAIGDYPLTVPEVLRIIFLGDGSRIERIAVFDWRMPRA
                     LTALTVGFALGLAGALTQSVTGNPLASPDILGITSGASAAAVTVLTFGGGVGAFAAVSG
                     KVATFGLPLAALAGGLITGAVVWILSSRGSFDAYRLVLFGIIITALMNAYIGFLMTRAE
                     LRDAATAQQWLAGSLNSTNWDRAVPVALVILICVPLLAWMAYTLTAAVLGQDLAAALGL
                     RVSRTQLTFLVIAVTLASIAVAAAGPIGFVAFVAPQLAVRITKLSTPPLVASAFMGAIL
                     LLGADLVVRTNIPVDLPVGIVTSAFGGVFLLYLLI"
     CDS             9888..10727
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 205.9; E-value:
                     1.1e-62)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_824"
                     /transl_table=11
                     /translation="MNNPISTPPNRGVSVNAQNICVGYGDNIIIDDLSVDFPSGEITTI
                     IGPNGCGKSTLLRAVSRLIPLRQGTVTVDGKDATTMKRKNLAKTVGVLPQTPSAPEGLL
                     VSDLVARGRHPHQSWINQWSAADEQEVLRALELTNTAHLAERSLEALSGGQRQRVWISM
                     VLAQQTDVLFLDEPTTYLDLSHSIDVLNLVTRLKHDLGRTIVMVLHDLNLAIRYSDHLV
                     VMKDGAIHASGSPAQVITPELLSEVFNLDAHVNPDPVMSEARGTTVPLIVPAAPPGM"
     PFAM_domain     9978..10421
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_824_0009"
                     /evalue="1.20E-30"
                     /label="ctg1_824"
                     /locus_tag="ctg1_824"
                     /protein_end="178"
                     /protein_start="30"
                     /score="106.9"
                     /tool="antismash"
                     /translation="DDLSVDFPSGEITTIIGPNGCGKSTLLRAVSRLIPLRQGTVTVDG
                     KDATTMKRKNLAKTVGVLPQTPSAPEGLLVSDLVARGRHPHQSWINQWSAADEQEVLRA
                     LELTNTAHLAERSLEALSGGQRQRVWISMVLAQQTDVLFLDEPT"
ORIGIN
        1 atctgcacaa tgaggaagcc acggaaaacg ccttccatga tggttggttc cgcaccggcg
       61 acatggctgt gatggaagaa gatggcttcg tgcgcattgt ttcccgcatt aaggaaatga
      121 tcatcaccgg tggtttcaac gtctaccctg gcgaggtcga agactgcctg ggccagcacc
      181 ctgatgtgga agagtgcgcc gtcgtggggc gtccgcgtaa ggacggctcc gaagacgtcg
      241 tagcctgtgt ggttctgcgg gcaggcgccg ccctggaccc ggatggacta aaggactact
      301 gccgcgagcg cctgactgca tacaaggttc cgcgcacctt ctaccacttc gaggagctgg
      361 ctactgacca gattggtaag ctgcgccgcc gcgaagttca ggccgacctg ctggatatgt
      421 tgggcctggt gccgaaggag aaggacgccg ccgacgacga cacagacggc tccgatgatt
      481 ccgatacttc cggtaaggcg aagccgctcg atgagcagcc agaccaccaa gaatctgacg
      541 tggagggtgt cgaggtagaa gatcttgccg acgcccagcc ggacgaaaca taactgggca
      601 gaccgaggcg tacacttttg gcgtttaacc ccactttgca aggcgaagac cacctcggaa
      661 ggctaatcct agctttccga ggtggtcttt tattcagtgc gcgttactta ttgaatagct
      721 cgcggaccca taactagttt atttaccagc tttcacgaga gcttcgtcaa tcttttcctt
      781 gtaccgatca atcgcccaag gaacagtcaa tgggttaatc atggaggaac ctgtgacaaa
      841 agactgatca gttggagcta cttctgcacc cttcgctata gcagcgatgc tggagtaggt
      901 agcatcagca tgcaattcct tgcgggaatc ttcatccgta tagaaggtga agatgagatc
      961 agaatcattg agtttatcaa ggttttctgc actgacagtt gcggaatcag tacctgcaac
     1021 gacgctgtcg cggaattctt cgacgacggg gtcgacttga agaccaagct tggaaacaaa
     1081 ctgcacacgt tgttctgtag gcaagaagat gccgtagttt cctacacctg cgttgtaaat
     1141 gaaactgaag gtgtgatcac cgtaggattc ttctttcgca tccgcgaatt ctgcattaat
     1201 gccgtcgatc aagccttgcg cctgatcctc ttttcccagc gccttcgcga cagtctttat
     1261 ctgttcgtcc caggtgatca cccaaggctc ttcttcgtag gcaaccgtcg gggcaatttt
     1321 actaatctga tcgtactgtt cctgggtgag gccggaccat ggcgccaaga taagatccgg
     1381 ttctagagct gcaatcttct cggcgctgag ttcctcacca cctgcgatta gctcaggttt
     1441 ctcgtcgtct gtgacaccta gttcttccag ttcttcgtta acccatggta aataaccaga
     1501 ctcatcggca ccccactcat aagattcaac ggctactgga accacaccga gggcaagtgc
     1561 agtttcagtg gaaccttgcc ccagcgtaat gacacgttct ggattccctt caatctcagc
     1621 aacgcctaaa gcgtgctcga tagtgcgggc atctccgggg ttcgcttcag ctttttcttg
     1681 gttctcgcca ctttcagcac aggctgcaag gccaaacacc aaagtcagag atgaaataat
     1741 agctgcaaga cgggcgatta aacctctacg gttacttgca tgcaacaccg aatggggcac
     1801 aaaagatgac atgctcattc cttctttcgt tgattccgcg catctcgata cgattcatcg
     1861 ttgccacggc ttttcagtaa ggccatcaga aagtctgata agcattttca ggatataggg
     1921 tactcaacac atcatgcaag gtttccctat ttaaactagt agacaccaga aacggcctta
     1981 accatcaaaa taacaagaaa ttcacagact tcattcattg aaccatctga agccttacct
     2041 tagtgtcgat ctctatggat tcatactccc ggaagttcgc cccacaagca caaccaggat
     2101 tacaattcct gggcgacggc tatagccatc aacacgcctt gtcatccgcc ggacaaacac
     2161 ttaatcaagc cctcgcgccg acatttagcc cgtcacccga gactttttgt cccaacaagg
     2221 accttggcgt cgacgaactt tctgcagctt tcaatgctgt agaaattgac acaccactgg
     2281 ggtcgctaga cgaagcacta aaagaactca atgatctttg ggtatcacac gctatccggt
     2341 acgattcccc acgttatctt gcgcatctaa attgccctat aacagcagca ggtttcgccg
     2401 gagcgaccat ttctgcagga ttgaatactg cagtcgaaag ctgggatcag ggacgcggcg
     2461 cagcaatcat cgaagaccaa atcataaagt ggttcgctgc ctccgcagga atgagcacca
     2521 ataacgcaac tgggacgttt acctcaggtg gtacacagtc aaacttacaa gccctttaca
     2581 cttcccgtga aaaagctttg aactcgggat cgagtctaga ctcccttcga gttctttgct
     2641 ccgaagaagc gcattattct attgcgcgct ccgcccatat tttaggcctt ccaaaggaag
     2701 ctgtcattac aatcgactgt gattcggatg gtgcactaaa aatttcctct ctccgccgca
     2761 caatcaactc cttaatcgag accgatggca aacacaccat agcctgctta gcccttactg
     2821 caggcacaac agatctagga gcaattgacc cgattgcaca agcaacccag atagcacagc
     2881 agcacggaat ttatgttcac gtagattgtg cttacggtgg ggccctgctg cttagcgata
     2941 aaaaccaaaa actactctct gggcttcacc aagcaaattc atttagcctt gactttcata
     3001 aaacgttttt ccaaccagtc gcatgttcag ctttgatcta tcgcgacctc actgaacttg
     3061 aacacgtcac ttggcattcg gattacctta atccagagac cgacactcga ttgaatcttg
     3121 caaaccgctc attacaaaca acccgacgct tcgatgcact caaattgtgg ctcagcctac
     3181 gagccgacgg acccaaagcg ctaggccaag cattcgatag atgttgcgaa attgctaccg
     3241 atgcagcgga gctaattcat gaatttccgg aactagaatt actcactacc ccgacattga
     3301 gcacagtcct tttccgtttc ctaccatcac tgccaggtag tccaagctca cacacttgta
     3361 tgcgggagac cgaagtcatc aacaaaatca acgatgcaat ccgtcgtcag ttgttcaacg
     3421 cgaatgaact cgtcatagcc agcaccaggc gcaacggcaa aacctacctg aaattcacaa
     3481 tactgaaccc acgtctcact aaggatgata ttcgctacgc attagagaaa atttgtgcgg
     3541 ctggaacaga tgaatgcgcc aaactacaaa gcaaggagga aattgatgac taagaaaatc
     3601 cacgaacaac cgtcaactaa tataactcag cgcgttgctg ccgatgaagt tttcgacatt
     3661 gtcgggatcg gcatcgggcc cttcaatctg ggaatggcgg cactcgcaca ccccttggtg
     3721 caatcgaatg agctcaaagc catctttttc gacgaaaatc aaggtttttg ttggcaccct
     3781 ggcgtaatgt ttccaaactc tacgatccag gttcccttca tggcggacct cgtcagtctg
     3841 gccgatccca ccagcccttg gagcttccta aactacttaa aaagacaggg gcgaatttat
     3901 cagttttaca ttcgcgaatc tttttaccca tatcgtacgg aatactctaa ttattgcgcc
     3961 tgggttgcag gccaacttag cacgctccaa tggtctagcc ccgtaacaga tgttcatcga
     4021 acgaaagacg gactttggcg agtccaagtt ggaggcacaa accccagggc cgtacttgcg
     4081 aagaatcttg tcaacggaac gggaactcaa ccttacgtcc cgacttcgct ccaacccaat
     4141 cttgtcgaat ctagaaatca gaccaaaaac attattcaca gttctgactt cctatttcat
     4201 gcagaacgtt tatcgaacag tgaagatata cagtcattga ccatcgtcgg ctccggccag
     4261 tctgcagcag aaatttatcg tcacctgatg gagcccttcg cggcaaccgg tcgccgtctt
     4321 aattggttaa caagatcacc ccgtttcttc ccaatggaat acactgcgct caccttggag
     4381 ttaactagta cggactacgt gcgccacttc cacaggcttc cagaagcgcg acgcgatcag
     4441 attaatcgcc aacagcgaaa cctgtacaag ggcatctccg gcgatttagt taacgatatt
     4501 tatgacacgt tatatcaact gtccattacc actccgctac gcggagagct acgccctgat
     4561 gtcaccgtgg agttgttcac agaaagtgat ctcaaaagct catacgaacg acacatcaac
     4621 gagcaggccg cggagagcca aatactactg aagctgacca acaacgaaac cggtaatgcc
     4681 gacatacatg cgactgatgc cgtcatcctc gctacaggct acggacgccc tgccatacct
     4741 tcgcatttga ttaccgctgc ggaagcaggc gaaatcaaca cagacaaaca aggacgtctg
     4801 gacgtaaatc tcgattttac ggttaaccag cggcgtgact tatacgtgct caatgccgaa
     4861 gaacataccc atagcctcaa tgccccagac ttgggaatgg gagcttggcg gaactcaatc
     4921 attctcaaca acatatgcgg ccgcacagtc tacgaagtgg aagattcctg gactttccaa
     4981 caatttggag gagaaaacgt atgagtaaat cacaacaatc ctgccaccca atcagcttga
     5041 ctcctggtgc aatgcatact tcgttaggga cagtcaatat tcgcccagtg caaccaacga
     5101 aggatgctaa aacactacat acatgggtca ctcatcctcg tgcgcacttt tggggtgctt
     5161 tagatgccag tgaacaagag attttggcag aataccgacg catcgaaaca agcaatgctg
     5221 aacaggcttg gctactatat ctcgacggaa atccgattgc tctttcggaa acctacgacc
     5281 caaagcacgt tgtacttaac acgtgttctg aattcactct ccatgaaggc gatatcggga
     5341 tgcacatcct agtttcgcct cccataggca agagcatcca tggactgacc gataacatct
     5401 tctctgctct agtccgctgg atttttagcc acggtgaagt gaaccgaatc gtcgtcgagc
     5461 ctgatgtctc taatttggga atccatcgaa aaaatgcccg aacaggattc acccaaccag
     5521 ggctcacaac aaccttaacg atgtccggaa aaccgaaaac cgcgttaatc caatattgca
     5581 cacgtcctga ttttctgggc tcgccgaatg cccctctgag ttatcctatt gcgcctaccc
     5641 cctgggagtt agttaagccc acagattcat ccagccccgt aacactcggt atcggccatt
     5701 tagccaaaac cgctgacgca gcacaccgcg aacttttcgc caaagcattg cgggaattca
     5761 cccatgaaag acttatatcc ccgcgaaaga tcaaagagtc tgctgatgag actgagtcta
     5821 acgatggcaa tcacagcgga tggcgttcct atcaagtcag ctggggatcc cggaaactga
     5881 tttttcgggc tcgcgagcat agattgcttc atctcagcgt agatccgctc agcatccacg
     5941 atccagcaga tctcacttgg acacccgata tcattacagg tatcgctgat gcagctgagc
     6001 aacttggtat cgcagaaagt tcgcgcgaaa cgtacctcga agaaatttca gcaactttcg
     6061 ccgcacgtgc gcggacttta gcccttccac ggccaacatc tactgaactg gccgacgcta
     6121 ctcgagatcc tgcagagcta ttccagacaa ttgaatctgc gatggtaatt ggtcaccctg
     6181 gcttcttagc taactccggt cgcggaggaa tgggcgaaac tcaactccgt gctttctcgc
     6241 cagaactcag tagtactact gatcttgttt ggtgtgccgt agacaaaaac tatgcacatc
     6301 tcgcgacaat cgaatacgag agggctcaag aatcagggtc ttctcattct tctaacgaag
     6361 ctatattgac tctggttccg gattttaaag accgctgtag actagctggc cttagtccgg
     6421 acgactacat cccgctacct gttcaccctt ggcagtggga gcaacgtttt accaccacat
     6481 tctccgctga tttagctgcc ggtcgaattg ttccactcgg tcgagaaggg gaagcctacc
     6541 gcccacaaca atctctgcgc actttcttca acacttctac tccagctgca ccatacgtaa
     6601 aaaccgccgt cgcagttcgt aacatgggtt ttactcgcgg gctttctgca cattacatgg
     6661 agtcaactcc acgagttaat ctctggctgc tgaatttaat cggagatgat ccagagtttt
     6721 tccaatcagg cattggattt ctccctgaga ttgcgtcagt aggatataca ggcagtgttt
     6781 accatcgcgt caccaacgac ggttctcaca ctaaaatgac cgctgcatta tggagacaat
     6841 ctccgttcag ccccgagacc actcccgcat tggatgacgg cgacacttta tctacgctag
     6901 cgggcatact tcactctgat gacgaaggat tacctcttat aagtgcctgg attaatcaga
     6961 gcggcttatc ggctgttgac tggatcaacc agcttttgac tctgtacgtt cgccctctca
     7021 ttcatgcact ggtgcgttac ggaattgttt tcatgcctca tacggaaaac gtcattttac
     7081 gtctcaatca gaataaaccg gttggcattt atcataagga ccttggcgaa gaaatagccg
     7141 tggtgtcgaa tgaaacgccg gttccttctg gactagaacg attgcgcgct cgctgcggtt
     7201 ctgactcacc cgaagattta tcccagcagg cgctttctat acatactgat gttattgacg
     7261 gcgttctccg ccatctcgca gcactgcttg acgatcatgc aattctcgag gaagacgtct
     7321 tttgggaaca gcttcggcac gttgcctccg tatatgccaa agatcatcct gaactaacta
     7381 ccggagactc tcggcaggca aggctttggc aagctctatt ggcaccgaga ttccgacatt
     7441 caacgctaaa ccggttacag cttcgcaacc ctcatactat ggttactctt ggtgaccaag
     7501 attcgtcgct catctacgct ggtgaactgg aaaatcctct gcacggtgtc taaatggtgc
     7561 cactcgcgtg tttgttccaa gacttaaggt ttatcactgg gctcaatgat ctaataagtt
     7621 agtctttact atgaaatcga caagattatc ttcgagacgt agcatgcgca agaactcgcg
     7681 agaatatacg cggtcatcgc ggtccctgcg cactcgtcgc attacagggt tgctagcact
     7741 cgctcttctc ctcgccgctg ctttactcgc tagtctactt tttggtgccc ggcctattgc
     7801 gttcgctgat gccgtgcaag cattaattaa tctaccttca ttgctagacg aacctcagtc
     7861 tggttccgcg gacgctcgcg ttatcgcaga tctccgctgg ccccgcaccc tcatcggctt
     7921 atttgtcggt gccgcactcg gtgtcgcagg tgcattaatc caaggccata cccgaaaccc
     7981 actggctgac ccaggactat tgggtgtttc agcgggcgca gcattcgctg tcgtcttagg
     8041 ctttttcgcg tttggactca cttctgcctt gagcacatcc gtcgtggctt tttgtggtgc
     8101 agttcttgcc actgcattag ttttcggtct tgcctcgctg ggtgggggac agatcaatcc
     8161 actcacgtta atccttggcg gcgctgcgct aacagcggtg ctacattcca tgaccactgc
     8221 gctcacactc atcgacgaca acagtctgga ccggatgcgc ttctggagcg ttggcgcatt
     8281 atctggcagg gatctttcaa ttttttgggg caccgcgccg tttatcgcgg tcggactcat
     8341 agttgcactt gcaaccgcgc ctacgttgaa tctgctgaat cttggcgacg acgcagctag
     8401 tgcgcttggc gtcaatactt accgggctcg gttggccggc atggtggtca tcgcgttact
     8461 tgcgggagct gccacggcgg ccgcgggccc gatcggcttc attggtttgg ttgtaccgca
     8521 tattgctcgt agtctgtgcg ggcctgatta ccggtggatt cttccatatt cagcgctgac
     8581 cggtgctagc ttgctgttgc tttcagatat tttgggccgt ctcattgccc gcccgggtga
     8641 attacaagtg ggaatcgtac tggcattcgt cggtgcgcca ttctttatgt acctcattta
     8701 tcggcggaag gtagttgctc tatgacgaac tcaccacatc tactgtcccg tccagtggtg
     8761 ccggggcggc cagcgctacg caaggggcgt atctctctgg tctggcgccc atgggttctt
     8821 tttagcacca tcgcgatgat ctgcgcagca gtgatcatct ttgctgcttc gatcgccatc
     8881 ggcgattatc ctttaactgt ccctgaggta ttgcgcataa ttttccttgg cgacggttct
     8941 cgtattgaac gtatcgcagt tttcgattgg cgtatgccac gggctttaac agcactcaca
     9001 gtaggttttg ctctgggttt ggctggtgcg ctaactcaat cagtgactgg caacccactt
     9061 gctagtccag acatacttgg tattacctct ggcgcttctg ctgccgccgt gaccgtgctg
     9121 accttcggtg gaggtgttgg agcttttgct gcggtatccg gaaaggttgc caccttcggc
     9181 ttaccccttg cagcactggc tggtggtctc attactggtg ctgtcgtctg gatcctttca
     9241 tcacggggca gtttcgatgc ctatcggctg gtgctattcg gaatcattat cacggctctc
     9301 atgaatgctt atatcggctt tttgatgaca cgagcagagt tacgggatgc cgctactgcg
     9361 caacagtggt tagcaggttc cctcaattcg actaactggg accgcgcggt tccggtagca
     9421 ctcgtcatcc tcatctgcgt cccgctatta gcttggatgg cgtacacact cactgctgcc
     9481 gtgcttggac aagatctcgc cgcagcactt ggccttcgcg tctcacgcac acagctaact
     9541 tttttggtta tcgcagtaac tctggcatca atcgccgtgg ctgcagctgg gccgatcgga
     9601 ttcgtcgcgt ttgtcgcacc gcagttggcg gtacgcatca ccaagctctc cacaccacca
     9661 ctggtcgctt ctgcattcat gggcgcaatc ttgctgttag gagctgacct cgtggttcgc
     9721 acgaatatcc ccgtagatct cccggttggc atcgtgactt ccgcttttgg tggtgtattc
     9781 cttctctacc tgcttatcag ctcgaatctc aagcggtcta ggtcgtcatg atcagattaa
     9841 aaacaactcg taacaagaac taagaataag acactaagaa taaaacgatg aacaatccaa
     9901 tttctacgcc ccctaaccgt ggtgtcagcg tcaatgcgca aaatatctgt gtcggttatg
     9961 gcgataacat catcatcgat gatctttcag tggatttccc aagtggagaa atcaccacca
    10021 tcatcggccc caacggttgt ggaaaatcta ccctcttgcg cgcagtttcc cgactcattc
    10081 cccttcgcca aggcacggtg accgtcgacg gtaaagacgc gaccacaatg aagcgtaaaa
    10141 acctggcaaa aactgtaggt gtcttgcctc agacccccag tgctccggag ggattattag
    10201 tctcggatct ggtcgcacgc ggacgccacc cgcaccagtc gtggatcaac cagtggtccg
    10261 ctgccgatga acaagaggtg ctgcgcgcac tcgaactcac gaacactgca catctagctg
    10321 aacgctcgct agaggcatta tctggaggcc aacgccaacg agtgtggatc agcatggtgc
    10381 ttgcacaaca aaccgatgtg ttgtttttag acgaacccac tacctacctg gatctttcgc
    10441 attccatcga cgttctgaat ttggtcacgc gcctgaagca tgatttgggt cgaaccatcg
    10501 ttatggtgct tcatgatctc aaccttgcga tccgttattc cgatcatctc gtagtgatga
    10561 aagatggcgc aatacacgcc agtggcagcc ctgctcaggt catcactcct gaattactca
    10621 gcgaagtctt caacctggat gcccacgtca accctgaccc agtcatgtct gaagcacgtg
    10681 gcactacggt tccactaatc gtgcctgctg cacctccggg catgtaaaac cctgccaccc
    10741 cattcagcaa cgccccaccc cacacaagtg gtttctaaaa caaaatcatg agaatttact
    10801 cacatttccc gcgagttatc cgcgtgagat aactcgcatg cactacggta gccaaagaca
    10861 acatgaacgt ttcctcatat tttctgtaaa ggatgccact gcatgtcttt gacaccgctt
    10921 gattccatgc gcgcccccgc catcattttt gctggtcaag cctcggaatg ggaaaagcag
    10981 ctgcataacg ccgctgccag ccaccacgcc gtcggccgcc tggacaatta cctgacccag
    11041 gcccgcagcc tggtcagccc ttacgcccgc accattgctt ccactgtccc tggagccatg
    11101 gagcgcctgg aagcgctcgt gcacgcaggt tcccaagaca ccggcgccag cacctccaaa
    11161 acggccgcga acaccgccaa tgacgttttc ccagccgtca gcatcccggg catcgtactc
    11221 agccagctgg ccgccattga tcaactgcgc gacctaggcc tcactctcga cgccgactcc
    11281 cctgccttcg ggcattccca gggcagcctc ggcatcgccg ccatcaaaca cccagtccac
    11341 gctcttgccc tggccatcct gatgggcaca gcagcaagcg tcgcccacgg ctccactgat
    11401 tcccgctcgc acatgctgct catccgcgac ctgccgcgcg aattcgtcga cacgtgcctc
    11461 agcaacaccg gctcggccgc catctcggtg gtcaacggca cccgcgcttt cgttgtctcg
    11521 ggcaccccgg acgagctcgc agcggtcgaa aacaacgtca cagaacgcgc cagcgcctac
    11581 aacgacgccc tggaggcccg cgaattcggc ggctcagaac ttactccgaa cttcacctac
    11641 ctaccggtcg cgctgccttt ccaccacgac agcctcaccg aagccgcaga cctcaccatc
    11701 gagtgggcta aggcctgcca actggacctc ggcgacaccg atatcgccac cgtcgtccgc
    11761 gagatcctgg tccacccatt cgactggacc gcgcagaccg cccagatggt cgaccaacac
    11821 atcagccaca cattggttct tgacgacggc ctggccaaac tcaccacccc gctggttgcg
    11881 ggcaccggcc tgagtgtggt cccggcctgg acgccgtcgc aacgcgataa cctcgctacc
    11941 cccggcgcgc aattgcctac tgcgcgcgac tggtccgagt tcgccccgcg cctggtcaca
    12001 ttgccggatg gcaagacgta cacgcaaacg aagttctctg cgctgaccgg tttgtccccg
    12061 atcatgctcg gcggcatgac gccaaccacc gtcgacccaa ccatcgtggc cgctgctgcc
    12121 aatgccggtt tctggacgga gatggccggc ggcggaatgt attccgaaga gctgttcact
    12181 gagctgaaga attcgctgat ccgccagctg cagcctggac gcaccgtcgc ctttaacacc
    12241 atgttcttcg atcgcttcat gtggaacttg cagtttggcc agacgcgcat cgtcccgaag
    12301 gcccgcgcga acggcgcacc gattactggt gtcaccattt cggctggtgt accggaagcc
    12361 gacgaagcca ccgaactgct cgcgcagctg cgcgccgacg gtttcccata tatttccttc
    12421 aaaccgggca ccaccaagca gatccgcgac atcctggcca ttgcagacgc caacccggag
    12481 caccagttga ttctgcagat cgaggacggc cacgccggcg gccaccactc ttggctggat
    12541 ctggatgaga tgc
//
