LOCUS       NZ_CP027793.1          10801 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP027793.1 Prescottella equi strain DSSKP-R-001 chromosome,
            complete genome.
ACCESSION   NZ_CP027793
VERSION     NZ_CP027793.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:27:47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1299267
            Orig. end    :: 1310068
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10801
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1304267:1305068](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5801)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10801
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10801
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="6"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             383..541
                     /locus_tag="ctg1_1264"
                     /transl_table=11
                     /translation="METVASSAVSSTKEEVQADSLLDHPTSGLMILAGLVGGLVVFGTS
                     VLGVMVP"
     CDS             632..1009
                     /locus_tag="ctg1_1265"
                     /transl_table=11
                     /translation="MTDRVGAGRQWYDRAGRPISADEAERLLGRPGYDRVGSTTILDMA
                     DLDWIRDVSTVWIGLDFNGENDSGPPLIFEAAVFDRDHETLEHRWYATEEEAMTAHEDF
                     VTAACGEAIDPVVLQTADPAP"
     CDS             1086..2015
                     /locus_tag="ctg1_1266"
                     /transl_table=11
                     /translation="MFGFVVHGSHLMQFARAVGDFDPAFEDVGRLAATGPGALVAPPTF
                     LMAADHFDPSYVRRPRPGTSWLGSRPRDSAQQSGFHMEQHFTFRRPVRAGDVLTAASRP
                     GATWEKSGRRAGTMTFGETLTDYRDCDGELVATARWVSAMVERKPDAPSPAAAADRSSS
                     RPAPVVEHGSAAQDLTVGSAWTVVLVEDLTRAQIVMYAGASGDFHPLHSDDVYARDRGH
                     PGVFAHGMLTMGMSGRAVTDRFGHASVRSFGGRIVSQVWPGDTLTARVEITAVRAGDDG
                     GTVADIALTTTNQQGVAVFSGAAEVLVD"
     PFAM_domain     1098..1496
                     /aSDomain="MaoC_dehydrat_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13452.8"
                     /description="N-terminal half of MaoC dehydratase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1266_0234"
                     /evalue="1.10E-16"
                     /label="ctg1_1266"
                     /locus_tag="ctg1_1266"
                     /protein_end="137"
                     /protein_start="4"
                     /score="61.3"
                     /tool="antismash"
                     /translation="VVHGSHLMQFARAVGDFDPAFEDVGRLAATGPGALVAPPTFLMAA
                     DHFDPSYVRRPRPGTSWLGSRPRDSAQQSGFHMEQHFTFRRPVRAGDVLTAASRPGATW
                     EKSGRRAGTMTFGETLTDYRDCDGELVAT"
     PFAM_domain     1659..1937
                     /aSDomain="MaoC_dehydratas"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01575.21"
                     /description="MaoC like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1266_0235"
                     /evalue="8.00E-19"
                     /label="ctg1_1266"
                     /locus_tag="ctg1_1266"
                     /protein_end="284"
                     /protein_start="191"
                     /score="67.5"
                     /tool="antismash"
                     /translation="LTRAQIVMYAGASGDFHPLHSDDVYARDRGHPGVFAHGMLTMGMS
                     GRAVTDRFGHASVRSFGGRIVSQVWPGDTLTARVEITAVRAGDDGGTV"
     CDS             2155..3276
                     /locus_tag="ctg1_1267"
                     /transl_table=11
                     /translation="MTFAEAISTLAGKVRDRKSEIVTEEATKNALIMPFISTVLGYDVF
                     DPSEVVPEFVADVGVKKGEKIDYAIVKNGEVQILIECKKVGEPLSLQHASQLFRYFAVT
                     SARIAILTNGQVYQIYTDGDAPNRMDEKPFLVFDLLDIDRSLISEVQKLSKESFDLESV
                     ISAAEELKYIGLVKRALANEIKEPTDDWIRYFVARVYDGKATQRVVDQFRGLVSKATSQ
                     YVSDQVNERLKSALGEGVGRDEIATSNVEVVDIIARDDVLAPEVPDPEIVTTDEELEGF
                     NIVRAIAVADVAPHRVVYRDSKSYCAVLLDDNNRKPILRLHLNGKSVKFVTTFEDGSKV
                     GIRHDIETVVDIYKFAEQIRSTVRGYVEVAAAD"
     PFAM_domain     2290..2526
                     /aSDomain="HSDR_N_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13588.8"
                     /description="Type I restriction enzyme R protein N
                     terminus (HSDR_N)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1267_0236"
                     /evalue="4.20E-09"
                     /label="ctg1_1267"
                     /locus_tag="ctg1_1267"
                     /protein_end="124"
                     /protein_start="45"
                     /score="36.5"
                     /tool="antismash"
                     /translation="DPSEVVPEFVADVGVKKGEKIDYAIVKNGEVQILIECKKVGEPLS
                     LQHASQLFRYFAVTSARIAILTNGQVYQIYTDGD"
     CDS             3441..3686
                     /locus_tag="ctg1_1268"
                     /transl_table=11
                     /translation="MNRSDGVVRGGGVAGAADPPRRADTPGGRPATARRSGALPALMRQ
                     LENKDQVTLAGTYMDLLPWPGSKIECTPECAAEETD"
     misc_feature    3624..3626
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             3701..4534
                     /locus_tag="ctg1_1269"
                     /transl_table=11
                     /translation="VGRHHRTSADAVLIELDPTLRRGRHREETSGPGAGLKAATVAAAT
                     GAIITAGAQLGAGSAAAAPAPAPLQVPAGLLPAGVELPQFQLPELPAAPALPTAQELIQ
                     QAKTIEIPAELPQVQDVVDNLTAAAEAAFGSVGTPNARAVKPVSGTLTSDFGPRWGSHH
                     GGLDIAAPIGTPVYAAADGVVVDAGPASGFGLWVRVKHDDGTTTVYGHVNDYQVNVGQH
                     VVAGQQIATVGNRGQSTGPHLHFEVWSPGGAKIDPSSWLEERGVAVTWRGASATM"
     PFAM_domain     4184..4471
                     /aSDomain="Peptidase_M23"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01551.24"
                     /description="Peptidase family M23"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1269_0237"
                     /evalue="1.30E-32"
                     /label="ctg1_1269"
                     /locus_tag="ctg1_1269"
                     /protein_end="257"
                     /protein_start="161"
                     /score="111.9"
                     /tool="antismash"
                     /translation="HHGGLDIAAPIGTPVYAAADGVVVDAGPASGFGLWVRVKHDDGTT
                     TVYGHVNDYQVNVGQHVVAGQQIATVGNRGQSTGPHLHFEVWSPGGAKIDP"
     CDS             complement(4617..4865)
                     /locus_tag="ctg1_1270"
                     /transl_table=11
                     /translation="VIEDLIELAHTQGVVCETSVGPDGCDEYVLACADGVTTVRLWVRP
                     DGRFSRAHGNAGSLSLGQVMAVCGLSYAARTSAAPAA"
     CDS             complement(5001..5801)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1271"
                     /sec_met_domain="Linocin_M18 (E-value: 5.2e-100, bitscore:
                     331.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLYRGLAPITDAAWASIEEEATRTFKRHIAGRTVVDVSGPHGT
                     DFSAVGLGRTTMIEAPASGVMARQRRVAPLVELRVPFKLSREEIDNVERGAQDADWDAV
                     KDAAKKIAFAEDRAIFEGYAAAGIEGIRASSSNPPLQLPEDVRDVPEVISQALSELRLA
                     GVDGPYSVLLSAEAYTQVSETSDHGYPIREHIRRLIDGDIIWAPAIDGAFVLTTRGGDF
                     DLQIGQDLSIGYLSHDAETVELYFQESLTFLTYTGEASVALAAR"
     PFAM_domain     complement(5049..5801)
                     /aSDomain="Linocin_M18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04454.14"
                     /description="Encapsulating protein for peroxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1271_0238"
                     /evalue="2.30E-99"
                     /label="ctg1_1271"
                     /locus_tag="ctg1_1271"
                     /protein_end="251"
                     /protein_start="0"
                     /score="331.9"
                     /tool="antismash"
                     /translation="MNNLYRGLAPITDAAWASIEEEATRTFKRHIAGRTVVDVSGPHGT
                     DFSAVGLGRTTMIEAPASGVMARQRRVAPLVELRVPFKLSREEIDNVERGAQDADWDAV
                     KDAAKKIAFAEDRAIFEGYAAAGIEGIRASSSNPPLQLPEDVRDVPEVISQALSELRLA
                     GVDGPYSVLLSAEAYTQVSETSDHGYPIREHIRRLIDGDIIWAPAIDGAFVLTTRGGDF
                     DLQIGQDLSIGYLSHDAETVELYFQESLT"
     CDS             complement(5798..6820)
                     /locus_tag="ctg1_1272"
                     /transl_table=11
                     /translation="VARSQLILTPLTPAAIFLVLTIDEGGEDTVRDVLSDVDGLRKAVG
                     FRVPDSGLVCVASIGSSAWDRLFDGPRPAELHEFVELDGGRHRAPATPGDLLFHLRAVS
                     MDLCFELASKIVGRLRGAATVVDETHGFRYFEQRDLLGFVDGTENPEGVEAAEAALVGD
                     EDPDFTGGSYVIVQKYLHDMDSWNAISTEEQERVIGRTKLDDIEFADDVKPSNSHVALN
                     TITDEDGDERQILRVNMPFGSLGDGEFGTYFIGYAATPSVTEEMLRNMFIGKPEGNTDR
                     ILDFSMAVTGGLFFSPTVEFFDDLPPAPAIRNADTEGTSPSPAADGSLGIGSLRRSSNR
                     "
     aSDomain        complement(5921..6805)
                     /aSDomain="TIGR01413"
                     /aSTool="tigrfam"
                     /description="Dyp_perox_fam: Dyp-type peroxidase family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1272_0042"
                     /evalue="3.90E-85"
                     /identifier="TIGR01413"
                     /label="ctg1_1272"
                     /locus_tag="ctg1_1272"
                     /protein_end="300"
                     /protein_start="5"
                     /score="284.0"
                     /tool="antismash"
                     /translation="LILTPLTPAAIFLVLTIDEGGEDTVRDVLSDVDGLRKAVGFRVPD
                     SGLVCVASIGSSAWDRLFDGPRPAELHEFVELDGGRHRAPATPGDLLFHLRAVSMDLCF
                     ELASKIVGRLRGAATVVDETHGFRYFEQRDLLGFVDGTENPEGVEAAEAALVGDEDPDF
                     TGGSYVIVQKYLHDMDSWNAISTEEQERVIGRTKLDDIEFADDVKPSNSHVALNTITDE
                     DGDERQILRVNMPFGSLGDGEFGTYFIGYAATPSVTEEMLRNMFIGKPEGNTDRILDFS
                     MAVTGGLFFSPTVE"
     PFAM_domain     complement(5921..6808)
                     /aSDomain="Dyp_perox"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04261.14"
                     /description="Dyp-type peroxidase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1272_0239"
                     /evalue="9.00E-95"
                     /label="ctg1_1272"
                     /locus_tag="ctg1_1272"
                     /protein_end="300"
                     /protein_start="4"
                     /score="317.5"
                     /tool="antismash"
                     /translation="QLILTPLTPAAIFLVLTIDEGGEDTVRDVLSDVDGLRKAVGFRVP
                     DSGLVCVASIGSSAWDRLFDGPRPAELHEFVELDGGRHRAPATPGDLLFHLRAVSMDLC
                     FELASKIVGRLRGAATVVDETHGFRYFEQRDLLGFVDGTENPEGVEAAEAALVGDEDPD
                     FTGGSYVIVQKYLHDMDSWNAISTEEQERVIGRTKLDDIEFADDVKPSNSHVALNTITD
                     EDGDERQILRVNMPFGSLGDGEFGTYFIGYAATPSVTEEMLRNMFIGKPEGNTDRILDF
                     SMAVTGGLFFSPTVE"
     CDS             complement(6911..8128)
                     /gene_functions="other (smcogs) SMCOG1094:ferredoxin
                     (Score: 180.4; E-value: 7.3e-55)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1273"
                     /transl_table=11
                     /translation="MLSEASKETVRATLPVVGAAIGDITTLFYRKMFDAHPELERDLFN
                     RGNQRQGEQQKALAGAVAAFATLQLDPDPERVDAILSRIAHKHASLGITADQYWIVHKH
                     LFEAIVEILGEAVTPEVASAWDEVYWLMANTLIAMEAGLYEKAGVAAGDVWRAVRVTRR
                     EHQSADTVSFTLASAENTPLPTFAPGQYISVAVHLPDGARQIRQYSLACDPTDEQWRIT
                     VKRIAGGTLADGTPAPAGEVSNFLYDNVFEGDELAVSLPFGDLVLPDDDAPLLLVSAGI
                     GCTPMIGMLEHLASTEDQRSVSVLHADRSVAQHAHRAELTELVEKLPSGVVHRWYEDLG
                     AREAFDGIRLGRADLTDVTLEPGTRAFLCGPLPFMLAMKESLLARDVPESNIHYEVFGP
                     DTWAGV"
     PFAM_domain     complement(6995..7303)
                     /aSDomain="NAD_binding_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00175.23"
                     /description="Oxidoreductase NAD-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1273_0242"
                     /evalue="2.80E-09"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="378"
                     /protein_start="275"
                     /score="37.7"
                     /tool="antismash"
                     /translation="LVSAGIGCTPMIGMLEHLASTEDQRSVSVLHADRSVAQHAHRAEL
                     TELVEKLPSGVVHRWYEDLGAREAFDGIRLGRADLTDVTLEPGTRAFLCGPLPFMLAM"
     PFAM_domain     complement(7334..7657)
                     /aSDomain="FAD_binding_6"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00970.26"
                     /description="Oxidoreductase FAD-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1273_0241"
                     /evalue="6.90E-08"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="265"
                     /protein_start="157"
                     /score="32.8"
                     /tool="antismash"
                     /translation="VRVTRREHQSADTVSFTLASAENTPLPTFAPGQYISVAVHLPDGA
                     RQIRQYSLACDPTDEQWRITVKRIAGGTLADGTPAPAGEVSNFLYDNVFEGDELAVSLP
                     FGDL"
     PFAM_domain     complement(7814..8110)
                     /aSDomain="Globin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00042.24"
                     /description="Globin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1273_0240"
                     /evalue="8.90E-06"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="105"
                     /protein_start="6"
                     /score="26.3"
                     /tool="antismash"
                     /translation="KETVRATLPVVGAAIGDITTLFYRKMFDAHPELERDLFNRGNQRQ
                     GEQQKALAGAVAAFATLQLDPDPERVDAILSRIAHKHASLGITADQYWIVHKHL"
     CDS             complement(8160..8606)
                     /locus_tag="ctg1_1274"
                     /transl_table=11
                     /translation="MQLTQFTDLGLRIVMRLATDPAGSGGPSTRAVAEQLAVSYTHATK
                     VVARLSELGVVTTRRGRGGGLAITDLGRTASVGWLTRQLEGDGEVVTCEGDKPCPLRRG
                     CRLRSSLRVAQDAFYTALDAMTVRDLAAPTPTTVLPVPDSPAVT"
     PFAM_domain     complement(8211..8600)
                     /aSDomain="Rrf2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02082.22"
                     /description="Iron-dependent Transcriptional regulator"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1274_0243"
                     /evalue="2.10E-22"
                     /label="ctg1_1274"
                     /locus_tag="ctg1_1274"
                     /protein_end="132"
                     /protein_start="2"
                     /score="79.8"
                     /tool="antismash"
                     /translation="LTQFTDLGLRIVMRLATDPAGSGGPSTRAVAEQLAVSYTHATKVV
                     ARLSELGVVTTRRGRGGGLAITDLGRTASVGWLTRQLEGDGEVVTCEGDKPCPLRRGCR
                     LRSSLRVAQDAFYTALDAMTVRDLAA"
     CDS             8859..9785
                     /locus_tag="ctg1_1275"
                     /transl_table=11
                     /translation="MTAEGMQQGVEEPSVARDENSVIVGVDGSDAAQAAVVWAARMCAE
                     RNLTLRIIHALNFSPYTYGAPYLDVAGIYDWMEDEGKEILARAAAAAREVSADLTLSTE
                     ISTMGGARWLVSLSEDSRALVLGASGSGAAGGIGSTAVNAASHGVCPVVVVHQRDGEVP
                     SEGPVVVGIDGSQTSERATAVAFEEAALRGVPLVAVHAWSDTPHGTLAGGRSAIRDPRA
                     FEDAEREVLSERLAGWRDRYPDVEVQRELYIDGPRTHLLAWSQKAQLVVVGSRGRGGFR
                     GLLLGSTSNELVQKAQCPVMVVRPERS"
     PFAM_domain     8922..9326
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00582.28"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1275_0244"
                     /evalue="5.80E-14"
                     /label="ctg1_1275"
                     /locus_tag="ctg1_1275"
                     /protein_end="156"
                     /protein_start="21"
                     /score="52.9"
                     /tool="antismash"
                     /translation="VIVGVDGSDAAQAAVVWAARMCAERNLTLRIIHALNFSPYTYGAP
                     YLDVAGIYDWMEDEGKEILARAAAAAREVSADLTLSTEISTMGGARWLVSLSEDSRALV
                     LGASGSGAAGGIGSTAVNAASHGVCPVVVVH"
     PFAM_domain     9360..9770
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00582.28"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1275_0245"
                     /evalue="3.00E-28"
                     /label="ctg1_1275"
                     /locus_tag="ctg1_1275"
                     /protein_end="304"
                     /protein_start="167"
                     /score="99.2"
                     /tool="antismash"
                     /translation="VVVGIDGSQTSERATAVAFEEAALRGVPLVAVHAWSDTPHGTLAG
                     GRSAIRDPRAFEDAEREVLSERLAGWRDRYPDVEVQRELYIDGPRTHLLAWSQKAQLVV
                     VGSRGRGGFRGLLLGSTSNELVQKAQCPVMVVR"
ORIGIN
        1 ttcgtggcca gcaggatgcg cccggatccg gcgtcggcgc ggatcgcgta gccgagtgcg
       61 gtcttcacta ccgaggccgg caggtgggtg aacgcggcga agccgatcag ggcgtcggtg
      121 tagaggtccg tgaagtactc gtgcttgcgt gccatgtcgc tcgtctctct ctcgggccac
      181 cgaacgctgt cggcggtgcg caggtctcgg gcggttgccg gcggaccctt cgggtgtgaa
      241 ctggagttcg tcagtttcct atctggtgcc gcgcaccttg tctcaatcaa ttcgctcagt
      301 aaatctatac catagggcat agattaatgt tgttcacgtc ggccggtccg gtcgacgacg
      361 tcgtgagatt cggtggtgcg agatggagac ggtggcgagt tcggcagtgt cgagtacgaa
      421 ggaagaggtg caggcggatt cgctgctcga tcaccccacg tcggggctca tgatcctcgc
      481 gggcctcgtc ggtgggctcg tcgtgttcgg gacgtcggtc ctgggggtga tggtgccgtg
      541 aaggaagctc gaggagcggc cggatgccgc cgcccggtag gttttcgctg agcgggcatg
      601 cgcactacgc gcggtgggac ggaggcgggc gatgacggat cgtgtcgggg cgggccggca
      661 atggtacgac cgcgcgggac gtccgatctc cgcggacgag gccgagcgac tcctcggacg
      721 ccccggctac gacagggtcg ggtccaccac gattctcgac atggcggacc tggactggat
      781 ccgcgacgtc tcgacggtgt ggatcggtct cgatttcaac ggcgagaacg attccgggcc
      841 tccgctgatc ttcgaggctg cggtcttcga ccgggaccac gagacgctcg aacaccgttg
      901 gtatgcaacg gaagaagagg cgatgacggc gcacgaggac ttcgtcaccg cggcgtgcgg
      961 cgaggcgatc gacccggtgg tactgcagac cgctgatccg gcgccctgac cggttgcgga
     1021 gcattcatgc gtaaggcaga tcgtccctcc ctctgaaccc tctgaacctt ctgaaagcag
     1081 gtggcatgtt cgggtttgtc gtgcacggtt cgcacctcat gcagttcgcg cgtgcggtcg
     1141 gcgatttcga tcccgccttc gaggacgtcg ggcgtctggc ggccaccggc ccgggcgcgc
     1201 tcgtcgcacc gccgacgttc ctgatggctg ccgaccactt cgatccctcc tacgtgcgcc
     1261 gcccgcggcc gggaacctcg tggctcgggt cgcgaccgcg tgacagcgcg cagcagtccg
     1321 gattccacat ggagcaacac ttcacgttcc gtcgccccgt ccgtgccggt gacgtcctga
     1381 ccgccgcatc gcggcccggc gccacctggg agaagagcgg acgccgcgcc gggacgatga
     1441 cgttcggcga gaccctcacc gactaccgcg attgcgatgg tgaactcgtc gcgaccgcgc
     1501 gctgggtctc cgccatggtc gagcgcaaac cggacgcgcc gtcccccgcc gcagcggccg
     1561 atcgctcgtc ctcccgacca gcaccggttg tcgaacatgg ctcggccgca caggatctca
     1621 cggtcggaag cgcatggacc gtcgtgctgg tcgaggatct gacgcgggcg cagatcgtca
     1681 tgtacgcggg tgcgtccggc gacttccatc cgctgcacag cgacgacgtg tacgcgcgcg
     1741 atcgcgggca cccgggtgtc ttcgcgcacg gcatgctgac gatgggcatg tccggccggg
     1801 ccgtcaccga ccgtttcggt cacgcgagcg tccggtcgtt cggtggccgg atcgtctcgc
     1861 aggtctggcc cggggacact ctcaccgcgc gcgtcgagat caccgccgtc cgggcgggcg
     1921 acgacggcgg gaccgtcgcc gatatcgcac tcaccaccac gaatcagcag ggggtggcgg
     1981 tcttcagcgg tgccgcggag gtgctggtgg actaggcgtc gagggatgga taggacgctc
     2041 gtgtccgcat agtttcgtgc gaattggtgc tttcaccaat ttggcgcttt tgtccctccg
     2101 ctgtgctcta cttcctgctc gaggccacta tctcgtgaac cagggggttg gagaatgaca
     2161 tttgccgaag cgatcagcac actcgcgggc aaggttcgtg acaggaagtc ggagatcgtc
     2221 accgaggaag cgaccaagaa cgcgctcatc atgccgttca tctcaacggt cctcggctat
     2281 gacgtcttcg acccgtcaga agtggtcccc gagttcgttg cggatgtggg cgtcaagaag
     2341 ggggagaaga tcgactacgc catcgtgaag aacggcgagg tgcagatcct catcgagtgc
     2401 aagaaggttg gggagccgct cagcttgcag catgcctccc aactgtttcg gtactttgcg
     2461 gttacctccg ctcgcatcgc gatcttgacg aacggtcagg tgtaccagat ctacacagac
     2521 ggtgacgctc cgaaccggat ggatgagaag ccttttcttg tgttcgacct cctcgacatc
     2581 gatcgttcgt tgatctccga ggttcagaag ctgtcgaagg aatccttcga cctcgaatcg
     2641 gtgatcagtg cagcggagga actgaagtac atcggcttgg tcaagcgagc actcgcgaac
     2701 gagatcaagg aaccgacgga cgattggatc aggtacttcg tcgcgagggt ttacgacggt
     2761 aaggcgacgc agcgagttgt cgatcagttc cgtggactcg tctccaaggc gacaagccag
     2821 tacgtttcgg accaagtcaa cgagcgcctg aagagtgcac tgggtgaagg agtcgggcgc
     2881 gatgaaattg cgacttcgaa tgtcgaagtc gtagatatca tcgctcgcga cgacgttctg
     2941 gcaccggagg tgccagatcc ggagatcgtg acaaccgatg aggaactcga ggggttcaac
     3001 atcgtgcgtg ccatcgcggt cgccgacgtt gcgccccatc gggtcgtcta tcgcgattcg
     3061 aagagctatt gcgccgtgct cctcgacgac aacaaccgca agccgattct tcgattgcac
     3121 ttgaacggaa aatcggtgaa gttcgtgacg accttcgaag acggcagcaa ggtgggcatc
     3181 cgtcacgaca tcgagactgt cgtcgacatc tacaagttcg cggaacagat ccgctccacc
     3241 gtccgagggt acgtcgaggt cgccgctgct gactgagttt acggacagat caagtgaagt
     3301 gccctcggca ggattcgaac ctgcgacacc ggctttagga gagccgtgct ctatcccctg
     3361 agctacgagg gcgggggcgg ggcgaacggg agtcgcgctg ttccgcagtt agggagtgta
     3421 gcggccggag ggcgtccgag atgaatcggt cggacggggt cgtgcgaggg ggtggggttg
     3481 ccggtgcggc tgatccgccg cgccgcgccg acacgcccgg tggccgcccc gcgaccgcgc
     3541 gtcgatcggg cgcgctccca gcactgatgc ggcaactcga aaataaagat caggtaacgc
     3601 tggcggggac gtatatggat ttgttacctt ggcccggcag caagatcgag tgcactccgg
     3661 agtgtgcggc cgaagaaacc gattgacgag gtaattgact gtgggacgcc atcaccggac
     3721 gtcagcagac gctgttctca tcgagctcga cccgacgctc cggcgcggcc gccaccgtga
     3781 ggagacctcc ggtcccggcg caggcttgaa ggccgccacg gttgccgcgg cgacgggcgc
     3841 gatcatcacc gcgggtgccc agctcggcgc cggcagtgcc gccgccgccc cggctcccgc
     3901 gccactccag gtccccgccg gactgctgcc tgcgggcgtc gaacttccgc agttccagct
     3961 ccccgagttg cccgcagctc cggcgctgcc gaccgcacag gaactgatcc agcaggccaa
     4021 gacgatcgag atcccggctg aactcccgca ggtgcaggac gtcgtcgaca acctcacggc
     4081 cgccgccgag gccgccttcg gttcggtggg cacgcccaac gcgcgcgccg tgaagccggt
     4141 gtccggcacg ctcacctccg acttcggacc gcgctggggc agccatcacg gcggcctcga
     4201 catcgcggca ccgatcggta ccccggtgta cgcggcggcg gacggcgtgg tcgtcgacgc
     4261 cggtcccgcg tccggcttcg gcctgtgggt gcgcgtcaag cacgacgacg gcaccaccac
     4321 ggtctacggt cacgtcaacg actaccaggt gaacgtcggt cagcacgtcg tcgccggcca
     4381 gcagatcgcc accgtcggca accgcggtca gtccaccggc ccgcacctgc acttcgaggt
     4441 gtggagcccg ggcggcgcca agatcgaccc gtcctcgtgg ctcgaggagc gcggtgtcgc
     4501 ggtcacgtgg cgaggtgcct cggccaccat gtgagccgat cccgaaacga cgcaaagtcc
     4561 ccgcccggat gggcggggac tttgtcgttc gagtggtgcg ccgagagccg cggagctcag
     4621 gcggccggcg cggcggacgt acgggccgcg taggacaggc cgcacaccgc catgacctga
     4681 ccgaggctca gcgatcccgc attgccgtgc gcgcgggaga agcggccgtc cggacgcacc
     4741 cacaaccgga ccgtcgtcac accgtccgcg caagcgagga cgtactcgtc gcaaccgtcg
     4801 gggccgaccg acgtctcgca cacgacgccc tgcgtatggg cgagttcgat caggtcctcg
     4861 atcacgaaag ctgctcctcg tacccccggg tcgaccgggt cctccgtcgc cgtccaggca
     4921 acagggatta ggttagcctt cgctcctgta ggcctgtcaa ccctgcgttc ggtcggtgtg
     4981 agcaaccact ccgggtgcgg tcagcgcgcc gcgagcgcga ccgacgcctc gccggtgtac
     5041 gtgaggaacg tcagcgactc ctggaagtac agctcgacgg tctccgcgtc gtgcgacagg
     5101 tagccgatcg acaggtcctg cccgatctgc aggtcgaagt cgccgccgcg cgtggtcagc
     5161 acgaacgccc cgtcgatcgc cggtgcccag atgatgtcgc cgtcgatgag gcgtcggatg
     5221 tgctcgcgaa tcgggtagcc gtggtccgac gtctcgctca cctgcgtgta cgcctcggcg
     5281 ctcagcagca ccgagtaggg gccgtcgacg ccggccaggc gcagttcgga cagcgcctgg
     5341 ctgatgacct cgggtacgtc tcggacgtcc tcgggcagct gcagcggcgg gttcgacgag
     5401 ctcgcccgga tcccctcgat gccggccgcg gcgtagccct cgaagatcgc ccgatcctcg
     5461 gcgaacgcga tcttcttcgc ggcatctttg accgcatccc agtccgcgtc ctgcgcgcca
     5521 cgttcgacgt tgtcgatctc ctcgcgcgag agcttgaacg ggacgcgcaa ctcgaccagt
     5581 ggagccactc ggcgctggcg ggccatcaca ccggaggcgg gggcctcgat catggtggtg
     5641 cgtcccagcc cgaccgcgga gaagtcggtg ccgtgcgggc cggagacgtc gacgacggta
     5701 cgtcccgcga tgtgccgctt gaaggttcgg gtcgcctcct cctcgatcga cgcccaggcg
     5761 gcgtcggtga tgggggcgag accgcggtag aggttgttca tcggttggaa ctccttctca
     5821 gactgccaat tccgagtgat ccgtcagcgg cgggagacgg gctcgtgcct tcggtgtcgg
     5881 cgttccggat ggccggcgcc ggcgggagat cgtcgaagaa ctcgacggtg ggggagaaga
     5941 acaggccgcc ggtgacggcc atggagaagt cgaggatgcg gtcggtgttg ccttcgggct
     6001 tgccgatgaa catgttccgc agcatctcct cggtgaccga cggcgttgcc gcgtacccga
     6061 tgaagtacgt gccgaactcg ccgtcaccga ggctgccgaa cggcatgttg acgcgcagga
     6121 tctgccgctc gtcgccgtcc tcgtcggtga tggtgttcag cgcgacatga gagttcgagg
     6181 gcttgacgtc gtcggcgaac tcgatgtcgt ccagcttggt gcggccgatg acgcgttcct
     6241 gctcctcggt ggagatcgcg ttccacgagt ccatgtcgtg caggtacttc tgcacgatga
     6301 cgtagctgcc gccggtgaag tcggggtcct cgtcgcccac gagggcggcc tcggcagcct
     6361 cgacgccttc cgggttctcg gtcccgtcga cgaaccccag caggtcgcgc tgctcgaagt
     6421 agcggaagcc gtgcgtctcg tcgacgacgg tcgcggcgcc gcgcagccgt ccgacgatct
     6481 tcgacgccaa ctcgaagcac aggtccatcg acaccgcacg aaggtggaac agcagatcgc
     6541 ccggtgtcgc gggggcgcgg tgccggccgc cgtcgagttc gacgaactcg tgcagctccg
     6601 cgggtcgcgg gccgtcgaac aggcggtccc acgcggacga accgatggag gcgacacaca
     6661 ccaatccgga gtcgggtacc cggaatccga cggccttgcg caggccgtcg acgtccgaga
     6721 gcacgtcgcg gacggtgtcc tcaccaccct cgtcgatggt gagcacgagg aagatcgccg
     6781 ctggtgtcag cggcgtcagg atcaactgag atcgggccac gccttacgtt agaacactcc
     6841 gggcgactcc gtcgcccgtg cgccttttcg gtagctgtag ctaccaaaaa ggcgcacggg
     6901 cgcgaagcgc ctacaccccc gcccaggtat ccgggccgaa gacctcgtag tggatgttcg
     6961 actcgggcac gtcgcgggcg aggagcgact ccttcatcgc caacatgaac ggcagcgggc
     7021 cgcagaggaa ggcgcgggtg ccgggctcga gcgtgacgtc ggtcagatcc gcacggccca
     7081 gccggattcc gtcgaacgcc tcgcgcgccc ccagatcctc gtaccagcgg tgcaccacgc
     7141 ccgacggcag cttctcgacc agttcggtga gctcggcgcg gtgcgcgtgc tgcgcgacgg
     7201 atcggtcggc gtgcagcacg gacacgctgc gctggtcctc ggtggacgcg aggtgctcga
     7261 gcatgccgat catcggggtg cagccgatgc cggccgagac caacagcagt ggcgcgtcgt
     7321 cgtcgggtag gaccagatcg ccgaagggca gcgacacggc cagctcgtcc ccttcgaaga
     7381 cgttgtcgta caggaagttc gatacctcac cggcgggtgc aggggtgccg tcggccagcg
     7441 tcccgcccgc gatgcgcttg acggtgatcc gccactgttc gtcggtgggg tcgcaggcga
     7501 ggctgtactg ccggatctgc cgcgccccgt ccggcagatg gacggcgacc gagatgtact
     7561 ggccgggggc gaacgtgggg agtggagtgt tctctgccga ggcgagcgtg aaggagacgg
     7621 tgtccgccga ctggtgctcg cggcgcgtca cccgcactgc gcgccacacg tcaccggctg
     7681 cgacaccggc cttctcgtac agcccggcct ccatcgcgat cagcgtgttc gccatcagcc
     7741 agtagacctc gtcccacgcc gacgcgacct cgggcgtgac ggcctcgccg aggatctcga
     7801 cgatcgcctc gaacaggtgc ttgtgcacga tccagtactg gtccgcggtg atcccgagcg
     7861 aggcatgctt gtgcgcgatg cgcgacagga tcgcgtccac ccgctcgggg tcggggtcga
     7921 gttgcagcgt cgcgaacgcg gcgacggcgc ccgcaagtgc cttctgctgc tcaccctggc
     7981 gctggttgcc ccggttgaac aggtcccgct cgagctccgg gtgggcgtcg aacatcttgc
     8041 ggtagaacag cgtcgtgatg tcgccgatcg ccgcgcccac gacgggcagg gtcgcgcgga
     8101 cggtttcctt cgaggcctcc gagagcatcg gattctcctt gtcggtcggg tttctacggt
     8161 taggtcactg ccggtgagtc gggtaccggc agcacggttg tgggggtggg ggcggcgagg
     8221 tctcggacgg tcatcgcgtc gagtgcggtg tagaacgcgt cctgggcgac gcgcagggac
     8281 gacctgagcc ggcagccccg acgcaacggg cacggcttgt cgccctcgca ggtcaccacc
     8341 tcgccgtcgc cctcgagctg acgggtcaac cagcccaccg acgcggtgcg accgagatcg
     8401 gtgatcgcca gcccaccgcc gcgcccacgg cgtgtcgtca cgacgccgag ttcgctcagt
     8461 cgcgcaacca ctttggtcgc gtgcgtgtac gagacggcga gctgctcggc gaccgcgcgg
     8521 gtgctgggac cgcccgaccc ggccgggtcg gtggccaggc gcatgacgat ccgcaggccc
     8581 agatcggtga actgcgtcag ctgcatgtct cgaccgtaga aaattggtat ctgcgattcc
     8641 aattagatgt gacgcgggtc gcggtgccgg agacgaagtc ccgaccttgg gcctgggcgg
     8701 acgggacttt ggtcccgaac cactcgggac cgtggcatcc ccacgcaaac aggcccgagt
     8761 gactaacgtc ggaggtggca cctcgatcgg ttcggtccgg ggcaggatcg accacgaatg
     8821 ccacaccgat tcgtcgcaaa cggaagaggg tgagcgggat gaccgcagag ggcatgcagc
     8881 agggcgtcga ggaaccgtcg gtcgccaggg acgagaactc ggtgatcgtc ggcgtcgacg
     8941 gatcggacgc cgcccaggcg gccgtcgtct gggccgcgcg gatgtgcgcg gagcgcaacc
     9001 tcaccctgcg aatcatccac gccctcaact tctcgccgta cacatacggg gcgccctacc
     9061 tcgatgtcgc cgggatctac gactggatgg aggacgaggg caaggagatc ctcgcccgcg
     9121 ccgccgcggc cgcccgcgaa gtctccgccg acctgacgct gtccaccgag atctccacga
     9181 tgggcggcgc ccgctggctc gtctcgttgt cggaggattc gcgcgcgctc gtcctcggcg
     9241 cgtccggcag cggtgcggcg ggcggcatcg gttcgacggc ggtcaatgcc gccagccacg
     9301 gcgtgtgccc ggtggtcgtg gtgcaccagc gcgacggcga ggtgcccagc gagggcccgg
     9361 tcgtcgtggg catcgacggc agccagacga gcgagcgtgc caccgcggtg gcgttcgagg
     9421 aggcggcgct gcgcggggtc cccctggtcg ccgtgcacgc ctggagcgac accccgcacg
     9481 gcaccctggc cggtggccgc agcgcgatcc gggatccgcg tgcgttcgag gacgccgagc
     9541 gcgaggtcct ctccgaacgt ctcgccggtt ggcgcgatcg ctacccggac gtcgaggtcc
     9601 agcgcgagct gtacatcgac ggaccgcgca cccatctgct ggcgtggtcc cagaaggcgc
     9661 agctcgtggt ggtcggcagc cgtggtcgcg gcggattccg cggattgctg ctgggctcga
     9721 ccagcaacga gctggtccag aaggcgcagt gccccgtgat ggtggttcgg cccgagcggt
     9781 cgtagagtcc actccgtaac gtccgtcaca ggtaaatacg gaatggggtc gccgaagtgc
     9841 gcatcggtat gggcttgaac tacagcggcg ggttcgccga gaccgtcgag gaggtcgccg
     9901 acctcgaacg ggcgggcctg gacatcgtct tcgtccccga ggcgtactcg ttcgacgcgg
     9961 tcagccagat cggctacctc gcggcgaaga cgtcgacggt ggagttggcg tcgggcatct
    10021 tccagatcta cacccgcacc ccgagcctca ccgcgatgac cgcggcgggt ctggactacg
    10081 tctcgaacgg ccgattcgtg atgggtatcg gggcgtcggg cccgcaggtg atcgagggct
    10141 tccacggcgt caagtacgac gcgccgctcg gccgcacccg cgagctcgtc gacatctgcc
    10201 gtcaggtgtg gcggcgggag aaggtcgagt accagggcaa gtactacaag gtgccgctgc
    10261 ccgccgacca gggcacgggg ctgggcaagc cgctcaagct catcaaccac cccgtgcgcg
    10321 accggattcc gatcgtcatc gcctcgctcg gaccgaagaa cgtggcgctg acggcggaga
    10381 tcgcggaggg ctgggaaccg atcttcttcc acccggagaa ggccgacgcg gtgtggggcg
    10441 acgcgctcgc gacgggcaag gccaagcgtg atccgagcct gggcgacctg cagatctacg
    10501 cgagcccggc gctggcgatc ggcgacgacg tcgagcccat gctggagtgg atcaagccga
    10561 atctggcgct ctacatcggc ggcatgggcg ccaagggcaa gaacttctac aacgacctcg
    10621 cgtgccgcta cgggtacgag gaggaggccg agaagatcca ggatctgtac ctggccggca
    10681 agaaggcgga ggccaccgcc gccgtgcccg acgacctcgt gcgcgcgatc tccttgatcg
    10741 gcaccgagag tttcgtcaag gaacgggtcg cggccttcgc ggccgccggc gccaccactc
    10801 t
//
