GCF_016728725.1_ASM1672872v1_genomic - 5 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP068168.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	RRE-containing	166,060	186,386
Region 2	terpene	882,096	903,076
Region 3	NRPS	1,112,420	1,158,752	phthoxazolin	NRP + Polyketide	4%
Region 4	NAPAA	1,407,334	1,441,383
Region 5	T3PKS	2,155,402	2,196,592	merochlorin A / merochlorin B / deschloro-merochlorin A / deschloro-merochlorin B / isochloro-merochlorin B / dichloro-merochlorin B / merochlorin D / merochlorin C	Terpene + Polyketide:Type III	7%

NZ_CP068168.1 - Region 1 - RRE-containing

Download region GenBank file

Download region SVG

Location: 166,060 - 186,386 nt. (total: 20,327 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001862.1	0.16	RiPP	geocillicin	Aeribacillus pallidus
BGC0001930.1	0.16	RiPP	pallidocin	Aeribacillus pallidus
BGC0001576.1	0.15	RiPP	divamide A	Prochloron didemni
BGC0000588.1	0.14	RiPP	microcin L	Escherichia coli
BGC0000792.1	0.14	Saccharide	polysaccharide	Enterococcus faecalis OG1RF
BGC0000294.1	0.14	NRP	acinetobactin	Acinetobacter baumannii
BGC0001314.1	0.14	Terpene	tirucalla	Arabidopsis thaliana
BGC0001120.1	0.14	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000589.1	0.14	RiPP	microcin M	Escherichia coli Nissle 1917
BGC0000587.1	0.14	RiPP	microcin H47	Escherichia coli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001862.1	0.46	RiPP	geocillicin	Aeribacillus pallidus
BGC0001930.1	0.46	RiPP	pallidocin	Aeribacillus pallidus
BGC0001576.1	0.46	RiPP	divamide A	Prochloron didemni
BGC0000588.1	0.44	RiPP	microcin L	Escherichia coli
BGC0000792.1	0.44	Saccharide	polysaccharide	Enterococcus faecalis OG1RF
BGC0000294.1	0.44	NRP	acinetobactin	Acinetobacter baumannii
BGC0001314.1	0.44	Terpene	tirucalla	Arabidopsis thaliana
BGC0001120.1	0.44	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000589.1	0.44	RiPP	microcin M	Escherichia coli Nissle 1917
BGC0000587.1	0.44	RiPP	microcin H47	Escherichia coli

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP068168.1 - Region 2 - terpene

Download region GenBank file

Download region SVG

Location: 882,096 - 903,076 nt. (total: 20,981 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000648.1	0.32	Terpene	carotenoid	Myxococcus xanthus
BGC0000637.1	0.22	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000644.1	0.21	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000646.1	0.21	Terpene	β-carotein	uncultured bacterium
BGC0000664.1	0.21	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001456.1	0.20	Terpene	isorenieratene	Streptomyces argillaceus
BGC0000698.1	0.20	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0001935.1	0.19	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001487.1	0.19	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001227.1	0.19	Terpene	isorenieratene	Streptomyces collinus Tu 365

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000648.1	0.65	Terpene	carotenoid	Myxococcus xanthus
BGC0000637.1	0.55	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000644.1	0.54	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000646.1	0.53	Terpene	β-carotein	uncultured bacterium
BGC0000664.1	0.53	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001456.1	0.53	Terpene	isorenieratene	Streptomyces argillaceus
BGC0000698.1	0.52	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0001935.1	0.51	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001487.1	0.51	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001227.1	0.51	Terpene	isorenieratene	Streptomyces collinus Tu 365

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP068168.1 - Region 3 - NRPS

Download region GenBank file

Download region SVG

Location: 1,112,420 - 1,158,752 nt. (total: 46,333 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000373.1	0.25	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001831.1	0.24	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001343.1	0.23	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001591.1	0.22	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.22	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001636.1	0.21	NRP	KK-1	Curvularia clavata
BGC0001699.1	0.21	Polyketide	nidulanin A	Aspergillus nidulans FGSC A4
BGC0001897.1	0.20	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001833.1	0.20	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001220.1	0.20	NRP	aculeacin A	Aspergillus japonicus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000373.1	0.59	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001831.1	0.57	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001343.1	0.56	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001591.1	0.55	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.55	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001636.1	0.54	NRP	KK-1	Curvularia clavata
BGC0001699.1	0.54	Polyketide	nidulanin A	Aspergillus nidulans FGSC A4
BGC0001897.1	0.53	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001833.1	0.53	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001220.1	0.53	NRP	aculeacin A	Aspergillus japonicus

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 1112419 - 1158752:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_984

Search NORINE for peptide: strict or relaxed

AMP-binding (575..972): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

ctg1_985

CAL_domain (187..492): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 25.3
NH2: 7.9
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

NZ_CP068168.1 - Region 4 - NAPAA

Download region GenBank file

Download region SVG

Location: 1,407,334 - 1,441,383 nt. (total: 34,050 nt) Show pHMM detection rules used

NAPAA: (AMP-binding and PP-binding and TIGR02353)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.21	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000244.1	0.18	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0001135.1	0.18	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.18	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001758.1	0.18	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001641.1	0.18	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001128.1	0.18	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1	0.18	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001479.1	0.18	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001168.1	0.18	NRP	livipeptin	Streptomyces lividans 1326

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.53	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000244.1	0.50	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0001135.1	0.49	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.49	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001758.1	0.49	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001641.1	0.49	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001128.1	0.49	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1	0.49	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001479.1	0.49	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001168.1	0.49	NRP	livipeptin	Streptomyces lividans 1326

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 1407333 - 1441383:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1242

Search NORINE for peptide: strict or relaxed

AMP-binding (24..425): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAESIGtVvK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 80% (moderate)

NZ_CP068168.1 - Region 5 - T3PKS

Download region GenBank file

Download region SVG

Location: 2,155,402 - 2,196,592 nt. (total: 41,191 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000286.1	0.20	Polyketide	viguiepinol	Streptomyces sp. KO-3988
BGC0001361.1	0.17	Terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0000205.1	0.16	Polyketide	bryostatin	Candidatus Endobugula sertula
BGC0001080.1	0.14	Other (Phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0000788.1	0.14	Saccharide	O-antigen	Salmonella enterica subsp. salamae serovar Greenside
BGC0000777.1	0.13	Saccharide	lipopolysaccharide	Escherichia coli
BGC0001947.1	0.13	Saccharide	K53 capsular polysaccharide	Acinetobacter baumannii
BGC0000799.1	0.13	Saccharide	colanic acid	Escherichia coli
BGC0000773.1	0.13	Saccharide	lipopolysaccharide	Escherichia coli
BGC0000760.1	0.13	Saccharide	emulsan	Acinetobacter venetianus RAG-1 = CIP 110063

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000286.1	0.53	Polyketide	viguiepinol	Streptomyces sp. KO-3988
BGC0001361.1	0.48	Terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0000205.1	0.47	Polyketide	bryostatin	Candidatus Endobugula sertula
BGC0001080.1	0.44	Other (Phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0000788.1	0.43	Saccharide	O-antigen	Salmonella enterica subsp. salamae serovar Greenside
BGC0000777.1	0.42	Saccharide	lipopolysaccharide	Escherichia coli
BGC0001947.1	0.42	Saccharide	K53 capsular polysaccharide	Acinetobacter baumannii
BGC0000799.1	0.42	Saccharide	colanic acid	Escherichia coli
BGC0000773.1	0.42	Saccharide	lipopolysaccharide	Escherichia coli
BGC0000760.1	0.42	Saccharide	emulsan	Acinetobacter venetianus RAG-1 = CIP 110063

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names