LOCUS       NC_014387.1            18276 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_014387.1 Butyrivibrio proteoclasticus B316 chromosome 1, complete
            sequence.
ACCESSION   NC_014387
VERSION     NC_014387.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:19:12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1226004
            Orig. end    :: 1244280
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..804
                     /locus_tag="ctg1_988"
                     /transl_table=11
                     /translation="MLGLKKYLIAEEERLNKIKQVIDKRLIDIPEGNLRITSSGKHIQY
                     MHCKEKDGKYQKQGEYLKKENMSLVRALAQKSYDQKMKKLVDRRLKQIQIISKEYSDDE
                     IELIYTNMNINRQALVTPVEKIWQQKVADWKSIPYTGKAFDEGIPEIYTKKGERVRSKS
                     EKLIADTLFDRGIEYKYECPISLKGYGLVYPDFTILSRKTGKEMYWEHDGRMDDPKYSE
                     KAVRKINSYIYNGIIPGDRLMLTFETSSTVLNDRTIKKMIDNFLL"
     protocluster    1..18276
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1233955:1235113](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(7952..9109)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..18276
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18276
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="2"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             893..2074
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     88.9; E-value: 9e-27)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_989"
                     /transl_table=11
                     /translation="MEKKMTSGEMAKKAGVSQKAIRLYDEKGLLKPTEYSEGNYRLYDD
                     AALQILEKIVALKQIGFSLEEIRDNLKSGEASDIKGALEIQLQKMEEKKYQLEKITDAI
                     KRTLARKEELDWDDVAEIVQYVSADQSADERHWDALKHTSGELDWYVRIFNSLDLKDGK
                     RVLDLGCGYAKLWRNNWTDIPKGTKITGYDIHGSWADDFARFIPENKDKLPEGADIKLE
                     FADLEDEKTWDKIDENGEYDVVIAHYLDSEIKDIEAIVAHASKVVAEDGLFSFNGANVA
                     NWNNLFKEAIEAIGEDSSFIDETIAGQTEKRNQYISMMEKYFARVESVLLPNFWHYTEA
                     KEIVEKMKDYYRAHEKAIAGYENKLLAYFEDKIEKDGEFVLEARSQFWHCYKK"
     PFAM_domain     905..1111
                     /aSDomain="MerR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13411.8"
                     /description="MerR HTH family regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_989_0052"
                     /evalue="2.00E-18"
                     /label="ctg1_989"
                     /locus_tag="ctg1_989"
                     /protein_end="73"
                     /protein_start="4"
                     /score="66.3"
                     /tool="antismash"
                     /translation="MTSGEMAKKAGVSQKAIRLYDEKGLLKPTEYSEGNYRLYDDAALQ
                     ILEKIVALKQIGFSLEEIRDNLKS"
     PFAM_domain     1346..1759
                     /aSDomain="Methyltransf_23"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13489.8"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_989_0053"
                     /evalue="1.90E-07"
                     /label="ctg1_989"
                     /locus_tag="ctg1_989"
                     /protein_end="289"
                     /protein_start="151"
                     /score="31.2"
                     /tool="antismash"
                     /translation="RIFNSLDLKDGKRVLDLGCGYAKLWRNNWTDIPKGTKITGYDIHG
                     SWADDFARFIPENKDKLPEGADIKLEFADLEDEKTWDKIDENGEYDVVIAHYLDSEIKD
                     IEAIVAHASKVVAEDGLFSFNGANVANWNNLFKE"
     CDS             2350..2916
                     /locus_tag="ctg1_990"
                     /transl_table=11
                     /translation="MPRTGLSKEEIIEKAATLANEKGLSYLSVTTLSEYLGIRKPSLYN
                     HVKSIDDLHYKLMIYGWKKVSDEIVAGIDSASPKEKLKKCAIAFYRFSMENPGVFEAML
                     WYNKYSDETLLEATEGLYSFFFEQTDSLGIDKEVANHLLRTYRAFLEGFIMLQIHNSFG
                     NPISIDESFEISMNVLISGMEQYRR"
     PFAM_domain     2599..2883
                     /aSDomain="TetR_C_33"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13305.8"
                     /description="Tetracyclin repressor-like, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_990_0054"
                     /evalue="1.70E-08"
                     /label="ctg1_990"
                     /locus_tag="ctg1_990"
                     /protein_end="178"
                     /protein_start="83"
                     /score="35.2"
                     /tool="antismash"
                     /translation="KCAIAFYRFSMENPGVFEAMLWYNKYSDETLLEATEGLYSFFFEQ
                     TDSLGIDKEVANHLLRTYRAFLEGFIMLQIHNSFGNPISIDESFEISMNV"
     CDS             2921..3289
                     /locus_tag="ctg1_991"
                     /transl_table=11
                     /translation="MGPIGIAPELKRKGYGKAILDYSLEKAAEMGFGAVLFEGNIGFYG
                     HSGFDYASKFGIRYHDLPEDADSSFFLCKELIPGYLDGITGVYQTPKGYYVEDADVEEF
                     DKNFPPKEKLKLPGQIFE"
     CDS             3311..4210
                     /locus_tag="ctg1_992"
                     /transl_table=11
                     /translation="MRANIDFKNYTDSDYEALCSFLIALNESDDRHIIWNWARLEWMIE
                     HPEFDKSLKNSIGLWTVDDKIVGAAIYDMYFGEGFCGVLPEYKDLYKAILEYACKELRD
                     DSGFGLAICDENMDELEMTKSLGFTPSDLDETIMERSLDVRSLDAKLPDGLKFFCPDPV
                     ENAYDLQWLFWQGFDHGDDKAEFEREEEIVPRVRKHFNKDLGVAAVNEKGEMVACCLLW
                     YMAGTDYVYVEPVCTIPAYRGKGIAKALIFEAFRRAKNLGATRAYVISNMEFYERLGFR
                     KKHHYSFFWKKDGKKGDT"
     PFAM_domain     3803..4150
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_992_0055"
                     /evalue="1.10E-12"
                     /label="ctg1_992"
                     /locus_tag="ctg1_992"
                     /protein_end="280"
                     /protein_start="164"
                     /score="48.3"
                     /tool="antismash"
                     /translation="NAYDLQWLFWQGFDHGDDKAEFEREEEIVPRVRKHFNKDLGVAAV
                     NEKGEMVACCLLWYMAGTDYVYVEPVCTIPAYRGKGIAKALIFEAFRRAKNLGATRAYV
                     ISNMEFYERLGF"
     CDS             4207..4716
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 74.6;
                     E-value: 1.5e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_993"
                     /transl_table=11
                     /translation="MIKIETERLLLHPISDEEMQKIIDDEKNPEMQKAYLEMLQGCLDN
                     PEDRVWFATWNMELKEQPNTIVGDLCFKGITDDGMVEIGYGLKEGYCGNGYMTEAVRAL
                     TEWALSQNKVSRVEAETDPDNMPSKRILANVGFIPNGEVGEEGPRFVLEKKITVCGKGH
                     RNLRSI"
     PFAM_domain     4246..4617
                     /aSDomain="Acetyltransf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13302.9"
                     /description="Acetyltransferase (GNAT) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_993_0056"
                     /evalue="3.20E-19"
                     /label="ctg1_993"
                     /locus_tag="ctg1_993"
                     /protein_end="137"
                     /protein_start="13"
                     /score="70.1"
                     /tool="antismash"
                     /translation="ISDEEMQKIIDDEKNPEMQKAYLEMLQGCLDNPEDRVWFATWNME
                     LKEQPNTIVGDLCFKGITDDGMVEIGYGLKEGYCGNGYMTEAVRALTEWALSQNKVSRV
                     EAETDPDNMPSKRILANVGF"
     CDS             4727..5512
                     /locus_tag="ctg1_994"
                     /transl_table=11
                     /translation="MCILSDKDNGGMSMDYIRVTKDNLEKEHICCAISNNKDVQVSSKK
                     AWLADRFDEGLVFLKSAERGKCFIEYIPAEYAWIPIEADGYMYIDCLWVSGSFKGHGYS
                     TDLLTACIEDSKGKGKKGLCILCAAKKKPFLADPKFLKYKGFTVADEADNGIQLWHLPF
                     EEKAGAPRFKECAKHPHIEEKGYVLYYTSQCPFNAKYVPVLEQTAKENDIPFHAIHIEN
                     REDAQNAPTPVTSYALFHDGEYVTNEQMNEKRFLKLIGH"
     PFAM_domain     5366..5497
                     /aSDomain="YoaP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14268.8"
                     /description="YoaP-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_994_0057"
                     /evalue="1.30E-20"
                     /label="ctg1_994"
                     /locus_tag="ctg1_994"
                     /protein_end="257"
                     /protein_start="213"
                     /score="72.7"
                     /tool="antismash"
                     /translation="PFHAIHIENREDAQNAPTPVTSYALFHDGEYVTNEQMNEKRFLK"
     CDS             5694..6119
                     /locus_tag="ctg1_995"
                     /transl_table=11
                     /translation="MKTFEAPQLMELGFEFTAEGVFGGSGTPVPNPPSAWLNDDNNNGG
                     SHTDVRVHFQNPLNVVCERFSIFIDSTVPIKSFGSSEFAITKESDTSFRIDVNRHLNAN
                     EWTDFIFQAIVEGGSIRESGTSGTMTELKIRDVRPLN"
     CDS             6178..7947
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 277.4; E-value:
                     4.2e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_996"
                     /transl_table=11
                     /translation="MGKIRYYFNKIKEGKLKDKLLIFKWIYGYAINHIPAIVIYTLLGM
                     TGIILGLFTSLNSRDLVDIITGHRTGELLRTFIIMIVLTVVNTCVSQISSYLSTKISLK
                     VNNEIKAQIFEGILRTDWQSLSKYHSGDLVMRCGSDASNIASGILTLVPNLIIYIFRFA
                     SALYMVCIYDWTFAIFALASIPITLISSRYSMKMMRKSGMGTMSASARMNGFHQETFSN
                     IQTIKAFDMLSYHIDRLKEIQKGYSEATLKYQKISMLNTFILTFVSMLVSYSAQAWGVY
                     KVWSGAITYGTMTMFIGLSSSLTGSVSNLISFVPTSLSLFNSADRVKSILDLPRDDYSN
                     AEDVERFGQEHAGKGIGVEARNVSFAYEGAENVFSKAEFNANPHETVAFVGPSGEGKTT
                     MLRLLLAIIRPGEGQVRITTGDGELEDSLYATAATRSLFAYVPQGNTMFSGTIAQNMRN
                     VKKDATDDEIIKALKMACAWDFVKKLPEGINSEMGEHGSGFSEGQAQRLSIARAILRQS
                     PILLLDEATSALDVWTEKEVLKNIMADEYPRTTIITTHRPSVLKQCDRVYAIRNGNCCK
                     LSDEEISEMESIA"
     PFAM_domain     6289..7098
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_996_0058"
                     /evalue="2.20E-35"
                     /label="ctg1_996"
                     /locus_tag="ctg1_996"
                     /protein_end="307"
                     /protein_start="37"
                     /score="122.7"
                     /tool="antismash"
                     /translation="VIYTLLGMTGIILGLFTSLNSRDLVDIITGHRTGELLRTFIIMIV
                     LTVVNTCVSQISSYLSTKISLKVNNEIKAQIFEGILRTDWQSLSKYHSGDLVMRCGSDA
                     SNIASGILTLVPNLIIYIFRFASALYMVCIYDWTFAIFALASIPITLISSRYSMKMMRK
                     SGMGTMSASARMNGFHQETFSNIQTIKAFDMLSYHIDRLKEIQKGYSEATLKYQKISML
                     NTFILTFVSMLVSYSAQAWGVYKVWSGAITYGTMTMFIGLSSSLTGSV"
     PFAM_domain     7303..7758
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_996_0059"
                     /evalue="9.00E-23"
                     /label="ctg1_996"
                     /locus_tag="ctg1_996"
                     /protein_end="527"
                     /protein_start="375"
                     /score="81.4"
                     /tool="antismash"
                     /translation="KAEFNANPHETVAFVGPSGEGKTTMLRLLLAIIRPGEGQVRITTG
                     DGELEDSLYATAATRSLFAYVPQGNTMFSGTIAQNMRNVKKDATDDEIIKALKMACAWD
                     FVKKLPEGINSEMGEHGSGFSEGQAQRLSIARAILRQSPILLLDEATS"
     CDS             complement(7952..9109)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_997"
                     /sec_met_domain="PF05402 (E-value: 1.3e-07, bitscore: 29.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.8e-07,
                     bitscore: 28.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRNNDFTLEYIGDTPCLLTHGQSAADRKKSLFLNDTGVFIWNLL
                     SKDLTIEEIFDSCYKHFEIDEADRPDAKRSIQSFMDSLCYSGMVIDTDFYKKLKLKKYV
                     SMNIAGICVNLFGKEELFDDSFMSFADDEYTCSADKTQNIYVYHIAPVIHKSGELIIRD
                     KEVSVIKTCDKYILIFPLWEHVDELHISPDGQKVSVFVKDTDNAKEEVFWAIRHAFLYM
                     ARIHNLFAIHSVSVEYDHKALLFSAGSGIGKSTHAALWNRLYGVRQINGDLNLLGKGDD
                     GKIYAYGMPWCGTSGIYDAKDYELRGIVLLRQDPNNFVSHLQPEAKALAIMNRIISPMW
                     NSEMSLSVIRFAQEVSADYPVWNYSCNTSDDAAAFIKSQIDSTTA"
     PFAM_domain     complement(8849..9016)
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_997_0060"
                     /evalue="3.90E-07"
                     /label="ctg1_997"
                     /locus_tag="ctg1_997"
                     /protein_end="87"
                     /protein_start="31"
                     /score="30.4"
                     /tool="antismash"
                     /translation="LFLNDTGVFIWNLLSKDLTIEEIFDSCYKHFEIDEADRPDAKRSI
                     QSFMDSLCYSG"
     CDS             9300..10616
                     /locus_tag="ctg1_998"
                     /transl_table=11
                     /translation="MASSIIHLAVTNELIKHHAFKDENRLKFGAILPDAGKGKAGHLNK
                     YIWGRNKKSYDFELFRDKFGELMRQDDLYLGYYLHLVQDICYRHFVYDKYHWNPMIPGN
                     VEKLHNDYSIINYYVTEKYDLKNDIVAPKDFERESINDLCVYDVNWLMESMGEYFKKVD
                     GDIFFFTREMADEYIAEAVELCLKELSAFMNGGKLIESYDNAWDNKIYSLLETTLNTRD
                     LGGYRIDGTENYTKYGRLIRSDVASYPSEKDIEFLKNTGITTIMDTRSVDEKEKKPHGL
                     AKVEGFEYYDIPIPEGSGVPDSVEAVPDSYIQIAHSEKISKVFKTIANAEGGVMFNCSA
                     GKDRTGVNSALLLWLCGVRKSDIVYDYMRTKKNNKERFELIHQNFPELDMNIVIPNENN
                     MISFMKMIEESYDTVENYFSAIGISRDEQKKITAKLTET"
     PFAM_domain     9939..10610
                     /aSDomain="Y_phosphatase3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13350.8"
                     /description="Tyrosine phosphatase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_998_0061"
                     /evalue="1.50E-47"
                     /label="ctg1_998"
                     /locus_tag="ctg1_998"
                     /protein_end="437"
                     /protein_start="213"
                     /score="162.7"
                     /tool="antismash"
                     /translation="LETTLNTRDLGGYRIDGTENYTKYGRLIRSDVASYPSEKDIEFLK
                     NTGITTIMDTRSVDEKEKKPHGLAKVEGFEYYDIPIPEGSGVPDSVEAVPDSYIQIAHS
                     EKISKVFKTIANAEGGVMFNCSAGKDRTGVNSALLLWLCGVRKSDIVYDYMRTKKNNKE
                     RFELIHQNFPELDMNIVIPNENNMISFMKMIEESYDTVENYFSAIGISRDEQKKITAKL
                     TE"
     CDS             complement(10630..12048)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 251.4; E-value:
                     2.1e-76)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_999"
                     /transl_table=11
                     /translation="MVYTAEYIQSIVSKQRQFFRTGKTLNVEWRINSLKTLKRMMVDNE
                     ALFLEALQKDLGRSKVEAYLCDIGPIITEINETIRGLRRWARPERHFSGIMCFPSVTTM
                     VYKMPYGVSLIISPFNFPLLLAVGVLAACISGGNTAVIKTSSKTVACTEVLKKCISEYF
                     PEEYITVIDGGHDVADLCLAERFDKIFYTGSPNVAKHVMAEAARHLTPLALELGGETGN
                     WCVVRKDANLKDAARKIAFFKLCNAGQICININQIAVAQEVADEFLNELKAEFTRQIGE
                     HPEENAEYPHLVSTSAYDNSAQTAEQYRSRILFGGNGNRDTLRYAPTIIYPVNADEEIV
                     RKELFSPLLPIVPYKDDEIDEILDIIEKREHPLAMYVFTKDTKWANKVMQTLQYGGGCI
                     NEVCIHMMVKGVPFNGTGHSGMGAYHGEWGFREFTHPQTVLTGKTFWNLPLREHPYTGK
                     VEKMKMQLLKWFER"
     PFAM_domain     complement(10732..12039)
                     /aSDomain="Aldedh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00171.24"
                     /description="Aldehyde dehydrogenase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_999_0062"
                     /evalue="5.20E-78"
                     /label="ctg1_999"
                     /locus_tag="ctg1_999"
                     /protein_end="439"
                     /protein_start="3"
                     /score="262.7"
                     /tool="antismash"
                     /translation="TAEYIQSIVSKQRQFFRTGKTLNVEWRINSLKTLKRMMVDNEALF
                     LEALQKDLGRSKVEAYLCDIGPIITEINETIRGLRRWARPERHFSGIMCFPSVTTMVYK
                     MPYGVSLIISPFNFPLLLAVGVLAACISGGNTAVIKTSSKTVACTEVLKKCISEYFPEE
                     YITVIDGGHDVADLCLAERFDKIFYTGSPNVAKHVMAEAARHLTPLALELGGETGNWCV
                     VRKDANLKDAARKIAFFKLCNAGQICININQIAVAQEVADEFLNELKAEFTRQIGEHPE
                     ENAEYPHLVSTSAYDNSAQTAEQYRSRILFGGNGNRDTLRYAPTIIYPVNADEEIVRKE
                     LFSPLLPIVPYKDDEIDEILDIIEKREHPLAMYVFTKDTKWANKVMQTLQYGGGCINEV
                     CIHMMVKGVPFNGTGHSGMGAYHGEWGFREFTHPQTV"
     CDS             12196..13338
                     /locus_tag="ctg1_1000"
                     /transl_table=11
                     /translation="MANISDKQRNHFMLRGPLSKRGYDWWWHSFTAEDEETGEEKPFFI
                     EYFTCNPDLAEDEPILGQHPGRKKDGKKPSYLMVKAGWWGEDATQLHRFYPWKDVTLPY
                     DTNLNLSAPECSLTETHMTGTVTVSKEEADSHPEYMSDSGSMIWDLSIDKKVAFNVGYG
                     ASKFFQRLNAFEMFWHAEGMKTEYSGMIICNGRRYIVKPKTCYGYADKNWGGDFTSPWV
                     WLSSNNLTSLLTGKKLENSVFDIGGGRPKVLGVALNRKLLSDFWYEGKSYEFNFSKFWT
                     FCRTKFECSETDTEVLWHVRQETTSAIMDTKISCQKKDMLFVNYEAPNGQKLHNRLFNG
                     GNGVGIIELYRKKGGKTELIDRVEAKNIGCEFGEYGELGE"
     PFAM_domain     12688..13314
                     /aSDomain="Tocopherol_cycl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14249.8"
                     /description="Tocopherol cyclase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1000_0063"
                     /evalue="5.60E-08"
                     /label="ctg1_1000"
                     /locus_tag="ctg1_1000"
                     /protein_end="373"
                     /protein_start="164"
                     /score="32.4"
                     /tool="antismash"
                     /translation="SKFFQRLNAFEMFWHAEGMKTEYSGMIICNGRRYIVKPKTCYGYA
                     DKNWGGDFTSPWVWLSSNNLTSLLTGKKLENSVFDIGGGRPKVLGVALNRKLLSDFWYE
                     GKSYEFNFSKFWTFCRTKFECSETDTEVLWHVRQETTSAIMDTKISCQKKDMLFVNYEA
                     PNGQKLHNRLFNGGNGVGIIELYRKKGGKTELIDRVEAKNIGCEFG"
     CDS             13342..15015
                     /locus_tag="ctg1_1001"
                     /transl_table=11
                     /translation="MAGSYVVIEKARELDYLKDFVVLPDSFGTDAYDNREDVIAIRACV
                     DSALDTLDEKTHFSEKLNNNRPVIIKPNLVSVYHNSGFDKADYPETTDPRVFEAVVRYI
                     RRFTNQITIAESSGKPMPTPASFRIAGYDRIARYYRTGLVALELRPVVRYMLPKAEVMK
                     EIYIPDTLDEVVKGNAFYISVPKMKTNLYTGVTLGFKNAMGTIPYFLRERNHSYLINKK
                     LADLLYLFKPDLTVIDGIIGGEGNTPAPVDPVRVGKIIAGNNSVEVDRITTRMMGFDPD
                     QNKLMMEAKARGFGDPETVIIGEPEVIPFRPAISSFMDEKTAREFPNLLALAGHTKNGA
                     PVITDKDTVTPEQALALEQACSGGCLAAAKTGLDYYNYKKSARQDFSLCIVEGEGVELE
                     GTRWWFDKAGKPYSLQDIAALPMHRMALGNCAAAARPSCDYFAEGCCDPAKCMAVVCHA
                     AGVTMPIMSPQNKGLVPTVTGMLGTILTRRRFIRSGEYVDCPHAQEDRIFPLPELSAED
                     AQKDYIPWPLPPMSKEEKKAQLRDQWKILLSVIGSGSRKF"
     PFAM_domain     13543..14160
                     /aSDomain="DUF362"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04015.14"
                     /description="Domain of unknown function (DUF362)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1001_0064"
                     /evalue="9.20E-41"
                     /label="ctg1_1001"
                     /locus_tag="ctg1_1001"
                     /protein_end="273"
                     /protein_start="67"
                     /score="140.3"
                     /tool="antismash"
                     /translation="VIIKPNLVSVYHNSGFDKADYPETTDPRVFEAVVRYIRRFTNQIT
                     IAESSGKPMPTPASFRIAGYDRIARYYRTGLVALELRPVVRYMLPKAEVMKEIYIPDTL
                     DEVVKGNAFYISVPKMKTNLYTGVTLGFKNAMGTIPYFLRERNHSYLINKKLADLLYLF
                     KPDLTVIDGIIGGEGNTPAPVDPVRVGKIIAGNNSVEVDRITT"
     CDS             15247..18276
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104:putative esterase (Score: 84.4; E-value:
                     1.4e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1002"
                     /transl_table=11
                     /translation="MRFTRFHKQRNGEMSMKQRNVKCFISKLLVMLLLVSTMGVCFKTN
                     VQAAAYNLMETYGAKYGYSGNCVHTFMLRNQNTVNSIKKDSNIVTLGNEFKPDYLLGSR
                     SATLISVDEAKRLGYYIPSNYRESTVPKINFSTVDEAMKLCYQNGLKMRGHTLVWHSQT
                     PTWFFRNGFSGNGGFVNQSTMDARLEFYVKTVLNHVYSSQYGSVVVYWDVANEIMHAQN
                     SGWEAVYGNNKTNAAYVKKAFNYAYECLEYFKLTDKVKLFYNDYNTYMVVNDEIKLVNY
                     INQGKKVCAGIGMQSHLSTSYPSVDYYTQALNAFIRAGFEVQITELDIKNNGDNDLNNY
                     CYQLFKNINTAKKNGGNISCITWWGPSDAETWLSGQKPLIWSNIGVSKPAYDYVVKAYT
                     DVFGNPGQSSGGSGSGSSETKPSGNTNATARIEDGWYYIKNPASQKYLTVEGNKADGWN
                     SVVISSGTGVDGQKWYVTNRSDGYVTLTSKLGNIMMDVANGENTDGANIGTYQGYGGNA
                     QQFIIKTTGTNGVYTIGTKCSNAARFLDIYEKKTNDGANVCQWTYNGNANQQWQFEKVE
                     ENAQQNPEPTPDPEPTPEPTPTPTPDPTPVTGSGLELEYSINSWGSGYQVSYKISNNSG
                     NTVDGWTLKVNKNQLNIDSSWNVNIKDSGDYYVITPVDWNKTIANGTSIEFGSIGVGQA
                     GSSFEYVLESAAGSSTGNESGSSSGGETGSEDPKPAPEPEPIPAPNPNYNPTARIENSI
                     PSKYSSVRYGEGSGTIVNISYTAHDTEANGRTYTKKANVYLPAGYSTDKKYNVLYLLHG
                     IGGNENEWGMTGNSSTVKAIMDNLAYYGDIDSFIVVTPNGKASASGSVNSFYNFGAELR
                     NDLIPYIDSHYSTNADRDHRAIAGLSMGGMQTINIGIGECMDLFSYFGAFSAAPTSNAA
                     SKTASLLNGNSYPIHYFYNVCGLQDNVAYSSHSQAAKNLPSVCDQFVDGQNYMWQELNG
                     AHDFNIWYLGFYNFAQIAFK"
     PFAM_domain     15418..16434
                     /aSDomain="Glyco_hydro_10"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00331.22"
                     /description="Glycosyl hydrolase family 10"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1002_0065"
                     /evalue="3.30E-62"
                     /label="ctg1_1002"
                     /locus_tag="ctg1_1002"
                     /protein_end="396"
                     /protein_start="57"
                     /score="210.6"
                     /tool="antismash"
                     /translation="GAKYGYSGNCVHTFMLRNQNTVNSIKKDSNIVTLGNEFKPDYLLG
                     SRSATLISVDEAKRLGYYIPSNYRESTVPKINFSTVDEAMKLCYQNGLKMRGHTLVWHS
                     QTPTWFFRNGFSGNGGFVNQSTMDARLEFYVKTVLNHVYSSQYGSVVVYWDVANEIMHA
                     QNSGWEAVYGNNKTNAAYVKKAFNYAYECLEYFKLTDKVKLFYNDYNTYMVVNDEIKLV
                     NYINQGKKVCAGIGMQSHLSTSYPSVDYYTQALNAFIRAGFEVQITELDIKNNGDNDLN
                     NYCYQLFKNINTAKKNGGNISCITWWGPSDAETWLSGQKPLIWSNIGVSKPAYDYVVK"
     PFAM_domain     16654..16926
                     /aSDomain="RicinB_lectin_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14200.8"
                     /description="Ricin-type beta-trefoil lectin domain-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1002_0066"
                     /evalue="4.70E-16"
                     /label="ctg1_1002"
                     /locus_tag="ctg1_1002"
                     /protein_end="560"
                     /protein_start="469"
                     /score="59.4"
                     /tool="antismash"
                     /translation="GQKWYVTNRSDGYVTLTSKLGNIMMDVANGENTDGANIGTYQGYG
                     GNAQQFIIKTTGTNGVYTIGTKCSNAARFLDIYEKKTNDGANVCQW"
     PFAM_domain     17083..17331
                     /aSDomain="CBM_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00553.21"
                     /description="Cellulose binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1002_0067"
                     /evalue="8.50E-16"
                     /label="ctg1_1002"
                     /locus_tag="ctg1_1002"
                     /protein_end="695"
                     /protein_start="612"
                     /score="58.2"
                     /tool="antismash"
                     /translation="LEYSINSWGSGYQVSYKISNNSGNTVDGWTLKVNKNQLNIDSSWN
                     VNIKDSGDYYVITPVDWNKTIANGTSIEFGSIGVGQAG"
     PFAM_domain     17611..18144
                     /aSDomain="Esterase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00756.22"
                     /description="Putative esterase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1002_0068"
                     /evalue="3.40E-17"
                     /label="ctg1_1002"
                     /locus_tag="ctg1_1002"
                     /protein_end="966"
                     /protein_start="788"
                     /score="63.0"
                     /tool="antismash"
                     /translation="KANVYLPAGYSTDKKYNVLYLLHGIGGNENEWGMTGNSSTVKAIM
                     DNLAYYGDIDSFIVVTPNGKASASGSVNSFYNFGAELRNDLIPYIDSHYSTNADRDHRA
                     IAGLSMGGMQTINIGIGECMDLFSYFGAFSAAPTSNAASKTASLLNGNSYPIHYFYNVC
                     GLQDNVAYSSHSQAA"
ORIGIN
        1 atgttaggac taaagaaata cttaattgca gaagaggaaa gactaaataa aatcaaacaa
       61 gttatagata aaaggcttat cgatatacct gagggtaatc tgaggataac atcatccggc
      121 aaacatattc agtacatgca ttgcaaagaa aaggatggca agtaccagaa acaaggagaa
      181 tatcttaaga aagaaaacat gtctcttgta agggcattgg ctcaaaagtc ttatgatcag
      241 aagatgaaaa aattggtaga taggagactt aagcaaatcc agattattag taaggagtac
      301 tcagatgatg agattgaact tatctatacc aatatgaaca tcaatagaca ggctctggta
      361 acacctgtag aaaagatatg gcagcagaaa gtggctgatt ggaaatcaat tccatataca
      421 ggaaaagcgt ttgatgaagg tatacctgaa atatatacca aaaaaggaga gagggtaaga
      481 tcaaagtcag aaaagctgat tgcagatact ttattcgata ggggaattga atataagtat
      541 gaatgcccaa tcagtttaaa aggctatgga ttggtatatc cggactttac aattctcagc
      601 cgcaagacag gaaaagaaat gtattgggag catgatggaa gaatggatga tcccaaatac
      661 tccgaaaaag cagtaaggaa gatcaattcg tatatttata atggaataat acccggggat
      721 agactaatgc ttacatttga gacatcaagc actgtgctca atgacagaac aataaagaaa
      781 atgattgata atttcctgct ataatactta gagaaaaaat aaaaagcctg ttgactcttc
      841 ccttagggaa tcccttaagg tggttttata aacaaataag gaggttctca aaatggaaaa
      901 gaaaatgaca tctggagaaa tggcaaagaa agcgggagta tcacagaagg caatacgtct
      961 ttatgatgaa aaagggctac ttaaacccac cgaatactct gaaggtaact atcgtcttta
     1021 cgatgacgca gcactgcaga ttttggaaaa gattgtcgcg cttaagcaga tagggttttc
     1081 cctcgaagaa atcagagata atctaaagag cggtgaagcc agtgacatta agggcgcgct
     1141 ggaaattcag cttcagaaga tggaggaaaa gaaatatcaa ctggagaaga tcactgacgc
     1201 aattaaaaga actttggcac gaaaggaaga actagactgg gatgacgttg cagaaatcgt
     1261 acagtatgta agtgctgacc agtctgctga tgagcgccac tgggatgcac tgaagcatac
     1321 aagcggagaa cttgactggt atgtgagaat cttcaattct cttgatctta aagacggaaa
     1381 aagagttctt gatctgggat gcggatacgc taagctctgg agaaacaatt ggactgacat
     1441 tcccaaggga acaaagatta cagggtatga cattcacggc agctgggcag atgattttgc
     1501 aaggttcatt cctgagaaca aagataaact gcctgaaggc gcagacatta agcttgaatt
     1561 tgcagatctt gaggatgaga agacctggga taagattgat gaaaatggcg aatatgacgt
     1621 agttatagct cattaccttg attctgagat aaaagatatc gaagctatcg tggcacatgc
     1681 cagcaaggta gtcgcagagg atggtctgtt ttctttcaac ggtgctaacg tggcaaactg
     1741 gaacaatctc tttaaagaag ctattgaagc tataggagaa gactcatcat tcatagatga
     1801 aacaatagct ggtcagacag agaagagaaa tcagtatata tccatgatgg agaaatattt
     1861 tgcaagggtg gagtcagttc ttttgcctaa tttttggcat tacactgagg caaaagaaat
     1921 cgtggagaag atgaaggatt actacagggc tcatgagaaa gctattgccg gatatgagaa
     1981 caagctcctt gcatattttg aagataaaat tgaaaaagac ggtgagtttg tgcttgaggc
     2041 aagaagccag ttctggcatt gctacaaaaa gtgaccggat tcaagaagag tgtcaacact
     2101 attataacaa gccaaaatca gaaaacagca ggcaacctgg aacaatacca gaaaaggaga
     2161 atgctattac tgaggcacta aattttttta agatgatata agtttgagga cagggaataa
     2221 aaaacctgtc ctttttctat tataaaaaaa tgcttggtaa agtggtcgta cagaaattat
     2281 tattgacaaa actaacagtg ttagtataat aaaactaaca atgttagttt gtgaggaatg
     2341 gaagtaaata tgccaagaac aggattatct aaggaagaaa taatagaaaa agctgctaca
     2401 ttagcaaatg aaaagggttt atcatatttg agcgtcacaa cgctttctga atatttagga
     2461 atcagaaaac cgtctctcta taatcatgta aagtcaatag atgatttgca ctataagctt
     2521 atgatctatg gttggaagaa ggtttcggat gagatagtag caggaattga ttcagccagt
     2581 ccaaaagaaa aactcaaaaa atgtgccata gcattttaca gattttctat ggagaatccg
     2641 ggtgtatttg aggcgatgct ttggtataac aaatactctg atgaaacttt gcttgaagct
     2701 acagagggct tgtattcatt cttctttgaa caaacagata gtcttggtat agataaagag
     2761 gtggcaaatc atttgcttag aacttacaga gcttttcttg aaggatttat catgctacag
     2821 atccataatt cttttggcaa tccgatttct attgatgaaa gcttcgagat atctatgaat
     2881 gtactgatat ctggtatgga gcagtatagg agatgataca atgggaccga tcggcatcgc
     2941 tcctgagctt aaaagaaaag gatatggcaa ggcaatcctg gactactctc ttgaaaaggc
     3001 tgcagaaatg ggctttggag cggtgctttt tgaaggaaat attggtttct atggacacag
     3061 cggttttgac tatgccagca agttcggaat cagataccat gaccttccgg aagatgctga
     3121 ttcttcattc ttcctgtgca aggagctgat tcctggatat cttgatggga tcaccggtgt
     3181 gtaccagact ccaaagggct actatgttga agatgctgat gttgaagagt ttgataagaa
     3241 ctttccgcca aaagaaaagc ttaagctgcc cgggcagatt tttgagtaaa ctataaggaa
     3301 gatattgatc atgagagcta atatagattt taagaattat actgacagtg attatgaggc
     3361 tttatgctct tttctgattg cattaaatga gagcgatgac aggcatatta tctggaactg
     3421 ggcaaggctg gaatggatga ttgaacatcc tgaatttgat aagagcttaa agaattccat
     3481 tggcctttgg actgtggacg acaaaatcgt tggcgctgct atctacgata tgtattttgg
     3541 cgagggcttt tgtggagtac ttccggagta taaagattta tataaggcca ttctggaata
     3601 tgcctgcaaa gagcttaggg atgattccgg cttcggacta gcaatctgtg atgagaatat
     3661 ggacgaatta gagatgacaa agagtcttgg atttacacct tcggacctgg atgagaccat
     3721 catggaaagg agtcttgatg ttcgctcact tgatgcaaaa ctcccggatg gccttaagtt
     3781 tttttgcccg gatcctgttg aaaatgcgta tgatctgcaa tggcttttct ggcagggatt
     3841 tgatcatggt gatgataaag ccgaatttga gagagaagag gagattgttc caagagtcag
     3901 aaagcatttt aataaggact taggtgttgc agctgtaaat gaaaagggag aaatggtggc
     3961 ctgttgtctg ctctggtata tggcagggac tgattatgtt tatgttgagc ctgtctgtac
     4021 tataccggca tacagaggga agggcattgc aaaagccttg atatttgagg cgtttcgcag
     4081 agccaaaaac cttggagcaa ccagggctta cgtgatttcc aatatggaat tctatgagag
     4141 gcttggattc aggaagaaac atcattattc atttttctgg aaaaaggatg gcaagaaagg
     4201 agatacatga taaaaataga gacggaaagg ctgctcctgc atccgatatc agatgaggaa
     4261 atgcagaaga ttatagatga cgagaaaaat ccggaaatgc agaaggcata tttagagatg
     4321 cttcaaggat gccttgataa cccggaagac agagtatggt ttgcaacctg gaacatggaa
     4381 cttaaggaac agcctaatac tatcgtggga gacctctgct tcaaaggaat cacagatgac
     4441 ggaatggtag aaataggcta tggccttaag gaaggctact gtgggaatgg atatatgact
     4501 gaggcagtaa gggctttaac tgaatgggcc ttgtctcaaa acaaagtatc acgagtcgag
     4561 gcagaaactg atccggacaa tatgccatca aagagaatac tggctaatgt tggatttatt
     4621 ccaaacggtg aagtaggaga ggaaggacca agattcgtct tagagaagaa aataaccgtg
     4681 tgtggaaaag gacaccggaa tttgaggagt atctgaagag gagacgatgt gcattttatc
     4741 tgataaggat aatggaggaa tgagcatgga ttatatcagg gtaacaaagg ataatttgga
     4801 aaaggaacat atttgctgtg ccatttccaa taataaagat gtacaagtat cttcaaagaa
     4861 agcctggctt gcggacagat ttgatgaagg tcttgtcttt cttaaaagcg ccgaacgtgg
     4921 taagtgtttc attgaatata ttcctgcaga atatgcatgg attccgatcg aggcggatgg
     4981 atatatgtat attgactgct tatgggtgtc cggctctttc aaagggcatg gatattccac
     5041 ggatctgctt actgcctgca tcgaagatag taaaggaaaa ggtaagaagg ggctttgtat
     5101 tttatgtgca gctaagaaaa aaccgttcct ggctgatccg aagttcctga aatacaaggg
     5161 ctttaccgtt gcggatgaag ctgataatgg tatccagctt tggcatctgc cgtttgaaga
     5221 gaaggcgggc gcaccacgat tcaaagaatg cgccaaacat cctcatatag aagagaaggg
     5281 ctatgttttg tattacacga gccagtgtcc gttcaatgca aagtatgttc cagttctgga
     5341 gcagactgca aaagaaaatg atattccatt ccatgctatt catattgaga acagggagga
     5401 tgcgcagaat gctccgactc ctgtgacgag ttatgcatta ttccatgatg gggagtatgt
     5461 tacaaatgag cagatgaatg aaaaaaggtt tctgaaactt atcggacatt aagttttccg
     5521 cttttaacat agacgactga caaggaaact tcttaaggaa taacaatctt tcaattttgt
     5581 tagattatag atatcacatt gttatttgtt aataattatt ttataattat tttataattt
     5641 cactatcaaa aatgaaaatg gatgataaaa aaccatttta atgggggtat acaatgaaga
     5701 cttttgaagc accacagtta atggaacttg gtttcgaatt tacagctgaa ggtgtttttg
     5761 gcggaagtgg aactcctgtt ccgaatccac ccagcgcatg gcttaatgac gataacaaca
     5821 atggcggatc tcatacagac gtcagagtac atttccagaa tccattaaat gtggtttgtg
     5881 agagattcag catctttatt gattcaacag taccaattaa gagctttgga agttctgagt
     5941 ttgcaataac aaaagaatct gatacatctt ttcgtattga tgttaatagg catcttaatg
     6001 ctaacgaatg gacagatttc attttccaag ctattgttga aggcggttct attcgtgaat
     6061 caggtacaag tggtacaatg actgaactta aaataagaga tgtacggcct cttaactaat
     6121 tattaaagat ttttattgga gcaccacata tgaacgtggt gcttcttttt ttacgatatg
     6181 gggaagataa gatattattt caacaaaatt aaagaaggaa agctaaaaga caagttattg
     6241 atattcaagt ggatatatgg atacgcaata aaccatatac ccgctattgt aatatacact
     6301 ttacttggta tgaccggcat aatacttggt ctttttacaa gccttaattc acgagacctg
     6361 gtagatataa tcacaggaca tcgcacaggg gaacttttgc gcacatttat aatcatgatt
     6421 gtacttacag tagtgaatac ttgtgtttcg cagatatcaa gttacctttc caccaaaatc
     6481 agtcttaagg ttaataatga gataaaggcg cagatctttg aaggaatatt acgaacggat
     6541 tggcaatccc tgtctaaata tcattccggt gaccttgtta tgagatgcgg aagtgacgct
     6601 tccaatattg catcaggaat tttgacactt gtaccaaacc ttataatcta tattttcaga
     6661 tttgcatccg ctttatatat ggtttgcata tacgattgga cattcgctat ttttgcgctt
     6721 gccagcatcc cgataacact gatcagttcg cgctattcta tgaagatgat gagaaagagc
     6781 ggaatgggaa ctatgtcagc atccgctaga atgaacggtt ttcatcagga gaccttctcg
     6841 aatattcaga caataaaagc ttttgatatg ctgtcatatc acatagacag gctaaaagaa
     6901 atacaaaaag gatattcaga agctacgctt aagtaccaga agatatcaat gctcaatact
     6961 tttatactga catttgtatc tatgcttgta tcctactctg cacaggcatg gggcgtatat
     7021 aaggtttgga gcggagctat cacatacgga acaatgacca tgtttatagg cctttcaagt
     7081 tctcttacag gctcagtttc taatcttatc agttttgtac caacgtctct tagcttgttt
     7141 aactcagctg accgagttaa aagcatattg gaccttccaa gagatgatta ttccaatgcc
     7201 gaagatgttg aaagatttgg gcaggagcat gcaggtaagg gaataggagt agaagccaga
     7261 aacgtgtcat ttgcttacga aggtgcagaa aatgtctttt ccaaggccga atttaatgct
     7321 aatcctcatg agacagttgc atttgtcgga ccttcaggtg aaggaaagac aactatgcta
     7381 agacttcttc ttgctataat aaggcctggt gagggacagg tgcgtataac gacaggtgat
     7441 ggggaacttg aagatagtct ctatgcaaca gctgcaacga gaagtctttt tgcatatgtt
     7501 ccacaaggaa atacaatgtt ctcgggaact atagctcaaa atatgagaaa tgtaaaaaag
     7561 gatgcaacgg atgacgagat catcaaagcc ctgaaaatgg cttgtgcatg ggactttgtc
     7621 aagaaacttc ctgaaggcat aaatagtgaa atgggagagc atggcagtgg cttttcagag
     7681 ggacaggccc agaggttgtc tattgccaga gcaatcctta gacagtcgcc tatacttctt
     7741 ttggatgaag caacctctgc tcttgatgta tggacagaaa aagaggtcct taagaatatc
     7801 atggcagatg aatatccaag gaccactatt attactacac atagaccttc agtattgaaa
     7861 caatgcgata gagtatatgc tatcagaaac ggcaactgtt gtaagttatc tgatgaggaa
     7921 atcagcgaga tggaaagcat cgcctgaata cttaagctgt tgtactatcg atttgggact
     7981 ttatgaatgc agctgcatca tctgaggtgt tgcagctgta attccataca ggatagtcag
     8041 cgctaacttc ctgcgcgaag cgaataacgc ttaaggacat ctcactattc cacatcggag
     8101 agatgattct gttcataata gccagagctt tagcttccgg ctgcaaatga cttacaaaat
     8161 tattaggatc ctgacgaagc agtactattc ctctaagctc atagtcttta gcatcataga
     8221 ttcctgaagt tccacaccat ggcatgccat acgcatatat tttgccatca tcaccttttc
     8281 ccaatagatt caaatcgccg ttgatctgtc ttacgccgta caacctattc caaagcgctg
     8341 catgtgtgct tttgccgatt ccggatccgg cagaaaagag aagagccttg tgatcatact
     8401 ctacggaaac cgaatgtatg gcaaataagt tatggattct tgccatataa aggaaagcgt
     8461 gacgaatagc ccagaatact tcttccttgg cattatcagt atctttaaca aaaacagata
     8521 ccttctgtcc gtccggtgat atatgaagct cgtcaacatg ctcccataac gggaaaatga
     8581 gaatatattt atcacatgtt tttatgacgg atacctcttt atcacgaatg atcagttcac
     8641 cggatttatg tattacaggt gcaatatgat agacataaat attctgggtt ttatcagctg
     8701 agcaagtgta ttcatcatca gcaaaagaca taaagctatc atcaaacagt tcttccttgc
     8761 cgaacagatt tacgcagata ccggcaatat tcatgctgac atatttcttg agtttaagct
     8821 ttttataaaa atcggtatct ataaccattc ctgaataaca aagggaatcc ataaagcttt
     8881 gaatggaacg ttttgcgtca gggcgatctg cctcgtctat ctcaaagtgt ttatagcagc
     8941 tatcaaagat ttcttcaatt gtcagatctt tggagagtaa attccagata aaaacaccgg
     9001 tatcatttag aaataagctt ttcttcctat ctgctgcgct ttgaccatgc gttagcagac
     9061 aaggagtgtc gccgatatat tcaagagtaa aatcgttatt tctgatcata ggttccccac
     9121 ttttaagaaa atacggttta atacgaataa taccagccta ttatagcatt aaagcagcta
     9181 ttatgtaggc tttttgattc ttacatgcta tgattatgag tatgttttag aaaacagtaa
     9241 tctcatatgt aaagttttat aagaaaaagt tttgaataat cggggacaaa ggggaaacaa
     9301 tggcatcaag tattatacat cttgcagtta ctaacgagct tattaagcac catgccttta
     9361 aggatgaaaa cagacttaag tttggagcta ttcttcctga tgcaggtaaa ggtaaagcag
     9421 gtcatttaaa taagtatatt tggggacgta ataaaaagtc ttatgatttc gaattattca
     9481 gagataagtt cggagagctg atgaggcagg acgacttata tcttggttat tatcttcacc
     9541 ttgttcagga catatgctac aggcactttg tatatgacaa gtatcactgg aatcccatga
     9601 ttcccggcaa tgtagagaaa cttcacaatg attattccat aataaattac tatgtaactg
     9661 aaaaatatga tttgaagaat gacatagtag ctcccaagga ctttgagagg gaatcaataa
     9721 atgacctatg cgtatatgac gttaactggc ttatggaatc tatgggggaa tactttaaaa
     9781 aagtggatgg cgacattttc ttttttacca gagaaatggc agacgaatac atcgccgagg
     9841 cagttgaact atgcttaaaa gagctaagcg catttatgaa cggaggaaag cttatagaga
     9901 gctacgacaa tgcttgggat aataaaatct actctctttt agaaactaca ttaaatacaa
     9961 gagatcttgg cggctacagg atagatggaa cagaaaacta cacaaaatac gggcgattga
    10021 taagaagtga tgttgcaagt tacccttctg aaaaagatat agaatttttg aaaaacactg
    10081 gtattacaac cataatggat accagatccg tagatgaaaa agaaaaaaag cctcatggcc
    10141 ttgccaaagt agaaggcttt gaatattacg atattcctat tcctgaagga agtggcgttc
    10201 cggatagtgt agaggcggtt ccggatagct atatacaaat tgcacattca gaaaaaataa
    10261 gtaaagtgtt taagacaata gctaatgctg aagggggagt aatgtttaac tgttctgcgg
    10321 gaaaagacag aaccggtgtc aattctgctc ttttattgtg gctctgtggt gtcagaaaga
    10381 gtgatatcgt atatgactac atgagaacca agaaaaacaa taaagagcgt ttcgaactga
    10441 tacatcagaa tttccctgaa cttgacatga atattgtgat tcctaacgaa aataatatga
    10501 tttcttttat gaagatgata gaagaaagct atgacactgt ggagaactat ttttcagcta
    10561 taggcattag cagagatgag cagaaaaaga taacagcaaa gctgacggag acttgagaaa
    10621 actatcaaat caccgctcaa accattttaa tagctgcatt ttcatttttt cgacttttcc
    10681 ggtgtaagga tgttctctta gagggagatt ccagaaggtt ttgcctgtaa gcacagtctg
    10741 gggatgagtg aattcacgaa agccccattc gccgtggtaa gcccccattc cgctgtgccc
    10801 ggtcccgtta aagggtacgc ccttgaccat catatgtata catacctcat tgatgcaacc
    10861 gcctccgtat tggagggtct gcataacttt atttgcccat ttcgtatcct tggtaaaaac
    10921 atacattgcc aacggatgct ctcttttttc aattatatcc agtatttcgt caatttcatc
    10981 gtccttgtag ggcactatgg gcagcagtgg gctgaatagt tccttacgga caatttcctc
    11041 gtctgcattt acagggtaga tgatagtggg agcatagcga agtgtatctc ggtttccgtt
    11101 accgccaaag agtattctgg aacgatattg ctccgctgtc tgagcgctat tatcgtaggc
    11161 tgaggtgctg acgaggtgcg gatattcagc gttttcctcc gggtgctcac caatctgtct
    11221 ggtaaattca gcctttagtt cattgagaaa ttcatctgca acctcttgag ctacggcaat
    11281 ctggttgata ttgatgcaga tttgtccggc gttgcagagc ttgaaaaaag caatcttacg
    11341 tgccgcatcc tttaggttag cgtccttacg cactacgcac cagttgcctg tttcgccgcc
    11401 aagttctagt gccagaggag tcaggtgtct ggctgcctcc gccattacat gtttggctac
    11461 gttgggagaa cctgtataga aaatcttatc aaagcgctca gcaaggcata ggtcggccac
    11521 atcgtgacca ccatctataa cagtaatata ttcttcagga aagtattcag aaatacattt
    11581 ttttaagact tcagtacagg caaccgtctt ggaactggtc ttgatgactg cagtgttacc
    11641 gcctgaaatg catgctgcca acactcctac cgcaagcagc aatgggaagt tgaaggggct
    11701 gataataagt gagacgccat agggcatttt atataccatg gtggtaacag aaggaaagca
    11761 catgataccg ctgaaatggc gctcaggtcg tgcccatcgg cgaagcccgc ggatagtctc
    11821 gttgatctct gtaataattg ggccgatatc acaaagatag gcttcgacct tgctgcgacc
    11881 aaggtccttt tgcagagctt ccagaaaaag agcttcgttg tcaaccatca tcctttttaa
    11941 ggtctttagg ctgttaatgc gccactcgac attcagggtc tttcctgttc tgaaaaactg
    12001 tcgctgtttt gacacaatgc tctgaatgta ttctgccgtg taaaccatag gagcctccgt
    12061 actcaactaa ttcgcttttt tgatttctaa atattataac ctttcgataa ttaattatca
    12121 atataactac ttttggggat gtttctatga tactatgaat tagtaaccgt cgggaaaaaa
    12181 gaatatgggg gaattatggc aaatattagt gataagcagc gaaatcattt catgttacgt
    12241 ggccctttga gcaaacgggg ctatgactgg tggtggcatt cattcacggc agaggatgag
    12301 gaaaccggag aagagaagcc attttttatt gagtatttta catgcaatcc tgatcttgct
    12361 gaagatgaac ctattctggg acaacatccc ggtagaaaga aggatggcaa gaagccatct
    12421 tatctgatgg tgaaggctgg ctggtggggc gaagacgcca cgcagctgca tcgcttttac
    12481 ccatggaagg atgtaaccct cccttatgat accaatctga atctctccgc gcctgaatgc
    12541 agcttgacag agacgcatat gaccggtacg gttacggtct caaaagaaga ggctgattct
    12601 caccctgaat atatgagtga cagcgggagt atgatatggg accttagtat tgataaaaag
    12661 gttgctttca atgttggcta tggtgcgagc aaattttttc agcgcctgaa cgcttttgag
    12721 atgttctggc atgctgaagg catgaaaacc gaatattccg gtatgatcat ctgtaatggt
    12781 cgaaggtata tagtaaaacc aaagacctgc tacggctatg ctgacaagaa ttggggcgga
    12841 gacttcacca gcccttgggt ttggctcagc agcaataatc ttacaagcct tctcacagga
    12901 aaaaagttgg aaaatagcgt gtttgatatc ggtggtgggc gccctaaggt tcttggagta
    12961 gctttgaacc gtaagcttct ttcagacttc tggtatgagg gcaagagcta tgaattcaat
    13021 ttttccaaat tctggacatt ttgtcgtact aagttcgagt gcagtgagac cgatacagag
    13081 gtgttatggc acgttcgaca ggaaacgact tctgctatta tggataccaa aatcagttgt
    13141 caaaagaaag atatgttatt cgtaaattat gaagcaccca atggccaaaa gctccacaat
    13201 cgtcttttta atggtggaaa cggagttggt attattgagc tctaccgcaa gaagggcggc
    13261 aaaaccgaac tgatagacag agttgaggcc aaaaacattg gttgtgaatt cggagaatac
    13321 ggagaattgg gagaataata tatggcgggg agttatgtcg taatcgaaaa agcacgtgaa
    13381 ctcgattatt tgaaggattt tgtggtactg ccggattctt ttggcactga tgcctacgat
    13441 aacagagaag acgttatcgc tatcagagct tgcgtggaca gcgcattgga cacccttgat
    13501 gaaaagacac atttttcaga gaaacttaat aataatcgtc cggtcattat caagcctaat
    13561 ctggtatcag tctatcacaa cagcggtttt gacaaggcag actatcctga gacaacggat
    13621 cctcgcgtct ttgaggcagt agtaaggtat ataaggcgct ttaccaatca aataaccatt
    13681 gcggagtcat cgggaaaacc catgcctaca cctgcaagct ttcgaatagc aggctatgac
    13741 cgaattgcca ggtattacag aaccgggctg gtggcattag aactaaggcc tgttgtgcgg
    13801 tatatgctgc ccaaggcgga ggtaatgaag gagatatata ttccggacac gcttgatgag
    13861 gtggtaaagg gtaacgcctt ttatatttcg gtgcccaaga tgaaaaccaa tctctatacc
    13921 ggtgtgacac taggctttaa gaatgccatg ggtacgattc cctattttct tagggaacgc
    13981 aaccacagct atcttatcaa taaaaaactg gcagatctgc tctacctttt taagccggat
    14041 ttgactgtca ttgacggaat tatcggcggc gaaggcaata cgcctgctcc tgtggatccg
    14101 gtgcgtgtcg gcaagattat cgcaggtaac aacagcgtgg aggtagacag gatcacaacc
    14161 cgcatgatgg gatttgaccc ggatcaaaac aagctgatga tggaagcaaa ggccagaggc
    14221 tttggcgacc ctgagacggt aattattgga gagccggagg ttattccatt tcgtccggca
    14281 atcagcagct ttatggatga aaagacggca cgggaatttc caaatctgtt ggcactggca
    14341 gggcacacca agaacggtgc tccggtcatt acagacaagg atactgtaac tcctgagcag
    14401 gcacttgcgc tggaacaggc gtgtagtgga ggatgtcttg cagccgccaa gacagggctt
    14461 gactattata actataaaaa gagtgcacga caggattttt ctctctgcat cgtagaaggt
    14521 gaaggtgtgg agcttgaggg aacgcgatgg tggtttgata aggccggtaa accatacagc
    14581 ttgcaggata ttgcagcctt gcctatgcac cgtatggcac tgggaaattg tgctgctgca
    14641 gctcgcccaa gttgcgacta ctttgcagaa gggtgctgtg atcctgctaa atgtatggct
    14701 gtggtatgtc acgctgcggg cgttacgatg ccaattatga gtccccaaaa taagggactt
    14761 gtgcctacag taacaggtat gcttggtacg atactcaccc gccgcaggtt tatccgaagt
    14821 ggcgaatatg tggactgccc tcatgctcaa gaggatagaa tttttcctct tccggagctg
    14881 agcgcagagg atgcacaaaa ggactatatt ccatggcccc ttcctcctat gtccaaagaa
    14941 gaaaaaaagg cgcagttgag agatcagtgg aaaattttgc tatcagtcat tggctcaggt
    15001 agcaggaaat tctagtattg cacaaatttc caaaacacta aatctaatat ttcgtaaaaa
    15061 tatatagata tttgtcacat ttataggaaa cttgattaat tgtatgaaaa taatgcacaa
    15121 aagtagcaaa ttgtgcaaat tattaagcaa ttattaagaa gttattacga aatattactg
    15181 ttagaatgat ggtgctcgag cacgtaacta aatagtcaaa tatgtggata ttgggggata
    15241 tctcgcatga ggttcacgag attccacaaa caaagaaatg gggaaatgag tatgaaacaa
    15301 agaaatgtga aatgttttat ttccaaactg ctagtcatgc ttctccttgt tagcacaatg
    15361 ggagtgtgct tcaagactaa tgtacaggct gccgcgtaca atctaatgga aacctacggc
    15421 gccaagtacg gttattccgg caactgtgtt cacaccttta tgctcagaaa tcagaacaca
    15481 gttaattcca tcaaaaagga ttctaacata gttacacttg gaaatgagtt taaacctgat
    15541 tatcttcttg gaagcaggtc tgcaactctg atttcagttg atgaggccaa gaggcttggc
    15601 tactacatcc cttcaaacta cagggagagt actgttccca agatcaactt tagcactgtt
    15661 gatgaagcta tgaaactctg ctatcaaaat ggtcttaaga tgagaggtca cactctggta
    15721 tggcattcac agactccgac ttggtttttc aggaatggct tttcaggcaa tggcggattt
    15781 gtaaatcagt ctacaatgga tgctcgtctt gagttctatg ttaagacagt tctcaatcat
    15841 gtgtattcaa gccagtatgg aagcgtagtt gtatattggg atgttgccaa tgagattatg
    15901 catgcccaga actcaggctg ggaggctgtg tatggaaaca acaagacaaa tgcggcctat
    15961 gtaaagaagg ctttcaatta cgcctatgag tgtcttgaat atttcaaact cacagataaa
    16021 gtaaagctct tttacaatga ttacaacacc tatatggtag ttaacgacga gatcaagctt
    16081 gtgaactata tcaaccaggg caaaaaagtc tgcgccggca tcggaatgca gtctcatctt
    16141 agcacaagtt atccatctgt tgattactat acacaggctc ttaatgcatt tataagagct
    16201 gggtttgagg tacagatcac tgagcttgat attaagaaca acggtgacaa tgatcttaat
    16261 aattattgct atcagctctt taagaatatc aatacagcca aaaagaatgg tggcaatatt
    16321 tcctgcatta cctggtgggg accatcagat gcagaaactt ggctctcagg ccagaagcca
    16381 cttatctggt ccaacattgg tgtcagcaag cctgcttatg attatgtagt taaggcttat
    16441 actgatgtat ttggaaatcc tggacagagt agtggtggca gtggaagcgg atcttcagag
    16501 actaagcctt caggaaacac aaatgctaca gcacgtatag aggatggctg gtactatatc
    16561 aaaaatcctg catctcagaa ataccttact gttgaaggca acaaggctga tggctggaac
    16621 agcgttgtta tcagttcagg aaccggtgtt gacggacaga agtggtatgt gacaaataga
    16681 tctgatggtt acgtaacact cacaagtaag cttggaaata tcatgatgga tgttgctaac
    16741 ggtgagaata ctgatggcgc aaacattgga acatatcagg gctatggcgg aaatgcccag
    16801 cagtttatca ttaaaacaac cggaacaaat ggtgtttata caattggtac caagtgttca
    16861 aatgcagcca gattccttga tatttatgag aaaaagacaa atgacggcgc aaatgtttgc
    16921 cagtggactt acaacggaaa tgcaaatcag cagtggcagt ttgaaaaggt tgaagaaaat
    16981 gctcagcaga acccggagcc aacacctgac cctgagccaa ctcctgaacc aacaccaaca
    17041 cctacaccgg atcctactcc tgtaacaggg tcaggtcttg aacttgaata ttctattaac
    17101 agttggggat caggctatca ggtaagctac aagatttcta ataactcagg aaatactgtt
    17161 gatggatgga ctctcaaggt aaacaaaaat cagcttaata ttgattcaag ctggaatgtt
    17221 aacattaaag attcaggaga ttattacgtg ataacacctg ttgactggaa caagacaatt
    17281 gcaaacggaa caagtatcga gtttggttca attggtgttg gccaggcagg tagctctttt
    17341 gaatacgtgc ttgaatctgc tgcaggaagc tctaccggaa atgaaagcgg ttcttcttca
    17401 ggcggagaaa caggaagtga agatccaaag ccagcaccgg agcctgaacc tattcctgca
    17461 cctaatccca attacaatcc tactgcaaga attgaaaact caattccttc taagtactct
    17521 tcagtaagat atggtgaggg ctcaggaaca attgtgaaca tctcttacac agcgcatgat
    17581 acagaggcaa atggacgaac atataccaaa aaagctaacg tatatttacc tgccggatat
    17641 agtacagata aaaagtacaa tgtactctat cttttgcacg gaattggcgg aaatgaaaat
    17701 gaatggggaa tgacaggtaa ttcatctaca gttaaggcta taatggataa cctcgcatat
    17761 tatggagata tcgactcctt catagtggtt acaccaaatg gaaaggcttc tgcaagcggt
    17821 tctgtgaact ctttctacaa ttttggagca gagcttagaa atgaccttat tccatatatc
    17881 gactctcatt acagcaccaa tgctgacaga gaccacagag ctattgcagg tctttcaatg
    17941 ggaggcatgc agacaattaa tatcggtatt ggcgagtgca tggatctgtt tagctatttt
    18001 ggagcattct ctgctgcacc aacaagtaat gctgcttcta agactgcatc actacttaat
    18061 ggcaactcat atccaatcca ttatttttat aatgtatgtg gacttcagga taacgtagct
    18121 tattcaagcc actcgcaggc tgccaagaat ctgccttctg tatgtgatca gtttgtagat
    18181 ggtcagaact atatgtggca ggaattaaac ggtgcacatg attttaatat ctggtacctc
    18241 ggtttctaca attttgctca gattgcattt aaataa
//
