LOCUS       NZ_CP014784.1          23161 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP014784.1 Pseudomonas alcaligenes strain NEB 585 chromosome,
            complete genome.
ACCESSION   NZ_CP014784
VERSION     NZ_CP014784.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:21:11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2745777
            Orig. end    :: 2768938
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23161
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[2755777:2758938]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13161
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..23161
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23161
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="6"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             530..1459
                     /gene_functions="regulatory (smcogs) SMCOG1125:LysR family
                     transcriptional regulator (Score: 323; E-value: 3.3e-98)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2518"
                     /transl_table=11
                     /translation="MNLNKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLR
                     ETFNDPLFVRTAQGMVPTPMAQNIIGPVRNALQLLRVSVQESRTFDAKQANKTYRISMT
                     DLSEQILLPPLFQRLRRLAPAVQIESFQAKRRETTKELAAGRLDFAVDAPLNTDPQVRH
                     VKLMEDRYVCAMRPGHPLAKDKLSLDEYLSQAHIQISSRRSGLGYIDLSLGKMGLQRKV
                     ALRSQHYLMASSVLHSTDMLMTVPERFARRHNLHHVDLPVSDVPALETHLYWHESTDQD
                     PANRWMREQLIELAQQISAQEKKAAEPA"
     PFAM_domain     554..730
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2518_0196"
                     /evalue="2.30E-15"
                     /label="ctg1_2518"
                     /locus_tag="ctg1_2518"
                     /protein_end="67"
                     /protein_start="8"
                     /score="56.4"
                     /tool="antismash"
                     /translation="NLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLRETFNDPLF
                     VRTAQGMVPTPMAQ"
     PFAM_domain     809..1411
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2518_0197"
                     /evalue="1.60E-27"
                     /label="ctg1_2518"
                     /locus_tag="ctg1_2518"
                     /protein_end="294"
                     /protein_start="93"
                     /score="96.3"
                     /tool="antismash"
                     /translation="QANKTYRISMTDLSEQILLPPLFQRLRRLAPAVQIESFQAKRRET
                     TKELAAGRLDFAVDAPLNTDPQVRHVKLMEDRYVCAMRPGHPLAKDKLSLDEYLSQAHI
                     QISSRRSGLGYIDLSLGKMGLQRKVALRSQHYLMASSVLHSTDMLMTVPERFARRHNLH
                     HVDLPVSDVPALETHLYWHESTDQDPANRWMREQLIEL"
     CDS             complement(1606..2733)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 461.1; E-value:
                     4.6e-140)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2519"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 4.8e-38, bitscore:
                     128.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.6e-27, bitscore:
                     91.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.9e-52, bitscore:
                     173.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPAEQDILIRDMARQFAQERLKPFAADWDREHRFPAEALKEMAD
                     LGFLGMLVPEEWGGAQTGHLAYAMALEEIAAGDGACSTIMSVHNSVGCMPILKFGSQEQ
                     KQRFLQPLASGAMLGAFALTEPQAGSDASDLRTRARRDGDHYVLSGAKQFITSGSHAGM
                     VIVFAVTDPAAGKKGISAFIVPTDTPGYSVVRVEDKLGQHASDTCQIQLDEVRIPASLR
                     LGEEGEGYRIALSNLEGGRIGIAAQSVGMARAAFEAARDYACERQTFGKPIIEHQAVAF
                     RLADMATQIAVARQMVHHAASLREAGQPCLTEASMAKLFASEMAEKVCSAAIQTLGGYG
                     YLKDFPVERIYRDVRVCQIYEGTSDVQRMVIARSL"
     PFAM_domain     complement(1609..2055)
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00441.26"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2519_0200"
                     /evalue="2.80E-51"
                     /label="ctg1_2519"
                     /locus_tag="ctg1_2519"
                     /protein_end="375"
                     /protein_start="226"
                     /score="173.8"
                     /tool="antismash"
                     /translation="GEGYRIALSNLEGGRIGIAAQSVGMARAAFEAARDYACERQTFGK
                     PIIEHQAVAFRLADMATQIAVARQMVHHAASLREAGQPCLTEASMAKLFASEMAEKVCS
                     AAIQTLGGYGYLKDFPVERIYRDVRVCQIYEGTSDVQRMVIARSL"
     PFAM_domain     complement(2089..2376)
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02770.21"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2519_0199"
                     /evalue="4.60E-26"
                     /label="ctg1_2519"
                     /locus_tag="ctg1_2519"
                     /protein_end="215"
                     /protein_start="119"
                     /score="90.9"
                     /tool="antismash"
                     /translation="AFALTEPQAGSDASDLRTRARRDGDHYVLSGAKQFITSGSHAGMV
                     IVFAVTDPAAGKKGISAFIVPTDTPGYSVVRVEDKLGQHASDTCQIQLDEV"
     PFAM_domain     complement(2389..2712)
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02771.18"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2519_0198"
                     /evalue="8.40E-38"
                     /label="ctg1_2519"
                     /locus_tag="ctg1_2519"
                     /protein_end="115"
                     /protein_start="7"
                     /score="129.6"
                     /tool="antismash"
                     /translation="ILIRDMARQFAQERLKPFAADWDREHRFPAEALKEMADLGFLGML
                     VPEEWGGAQTGHLAYAMALEEIAAGDGACSTIMSVHNSVGCMPILKFGSQEQKQRFLQP
                     LASG"
     CDS             complement(2743..3510)
                     /NRPS_PKS="Domain: PKS_KR (6-172). E-value: 1.4e-17. Score:
                     56.0. Matches aSDomain: nrpspksdomains_ctg1_2520_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.2; E-value: 1.8e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2520"
                     /sec_met_domain="adh_short (E-value: 1.6e-30, bitscore:
                     104.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIEDSVFLITGGGSGLGLATARELVAQGAKVLLLDINAEAGAKA
                     AAELGERARFLRADISSEADGRAAVEEALQAFGAVHGLVNCAGVAPAEKVIGRNGAHGL
                     DSFRRTIEINLIGSFNMLRLAAEAMARNQPNEGGERGVIINTASVAAFDGQMGQCAYSA
                     SKGGVAAMTLPAARDLARSGIRVMCIAPGIFETPMMAGMPQEVQDSLAANVPFPPRLGR
                     PAEYAALVRHIVENAMLNGETIRLDGALRMAAK"
     PFAM_domain     complement(2905..3492)
                     /aSDomain="adh_short"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00106.27"
                     /description="short chain dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2520_0201"
                     /evalue="3.40E-50"
                     /label="ctg1_2520"
                     /locus_tag="ctg1_2520"
                     /protein_end="202"
                     /protein_start="6"
                     /score="170.3"
                     /tool="antismash"
                     /translation="VFLITGGGSGLGLATARELVAQGAKVLLLDINAEAGAKAAAELGE
                     RARFLRADISSEADGRAAVEEALQAFGAVHGLVNCAGVAPAEKVIGRNGAHGLDSFRRT
                     IEINLIGSFNMLRLAAEAMARNQPNEGGERGVIINTASVAAFDGQMGQCAYSASKGGVA
                     AMTLPAARDLARSGIRVMCIAPGIFETPMMAGM"
     aSDomain        complement(2995..3492)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2520_PKS_KR.1"
                     /evalue="1.40E-17"
                     /label="ctg1_2520_PKS_KR.1"
                     /locus_tag="ctg1_2520"
                     /protein_end="172"
                     /protein_start="6"
                     /score="56.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VFLITGGGSGLGLATARELVAQGAKVLLLDINAEAGAKAAAELGE
                     RARFLRADISSEADGRAAVEEALQAFGAVHGLVNCAGVAPAEKVIGRNGAHGLDSFRRT
                     IEINLIGSFNMLRLAAEAMARNQPNEGGERGVIINTASVAAFDGQMGQCAYSASKGGVA
                     AMT"
     CDS_motif       complement(3406..3492)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2520_0001"
                     /evalue="4.20E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_2520"
                     /protein_end="35"
                     /protein_start="6"
                     /score="29.0"
                     /tool="antismash"
                     /translation="VFLITGGGSGLGLATARELVAQGAKVLLL"
     CDS             3608..3997
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     78.6; E-value: 1.3e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2521"
                     /transl_table=11
                     /translation="MSITYSISDLARELDVTTRAIRFYEEQGMLVPERRGQERIYRPKD
                     LVALKLILRGKRIGFSLAECKELIDLYDPSSGNRKQLETFMAKIAARRAQLEQQLLDIQ
                     QMQLELDTAEERCLAALAATESAVS"
     PFAM_domain     3620..3817
                     /aSDomain="MerR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13411.8"
                     /description="MerR HTH family regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2521_0202"
                     /evalue="2.00E-17"
                     /label="ctg1_2521"
                     /locus_tag="ctg1_2521"
                     /protein_end="70"
                     /protein_start="4"
                     /score="63.1"
                     /tool="antismash"
                     /translation="YSISDLARELDVTTRAIRFYEEQGMLVPERRGQERIYRPKDLVAL
                     KLILRGKRIGFSLAECKELID"
     CDS             4026..5189
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 378.8; E-value:
                     4.9e-115)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2522"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2e-39, bitscore:
                     132.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.5e-27, bitscore:
                     92.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 9.5e-42, bitscore:
                     140.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYPTLNFGLGETIDMLRDSVHQFAQAELAPRAAQIDRDNEFPMD
                     MWRKFGDMGLLGMTVEEEYGGTNMGYLAHVVAMEEISRASASVGLSYGAHSNLCVNQIR
                     KNGSEAQKQKYLPKLCSGEHIGALAMSEPNAGSDVVSMKLRAEKRGDRYVLNGNKMWIT
                     NGPDAHTYVIYAKTDINAGSRGMTAFIVERGYKGFSRHQKLDKLGMRGSNTCELVFEDC
                     EVPEENILGAEGAGVRVLMSGLDYERTVLSGGPTGIMSACMDVVLPYVHERQQFKQSIG
                     EFQLVQGKLADMYAGMNASKSYLYNVAKACDRGEESRKDAAAVILYTAEMATKMALDTI
                     QLLGGNGYTNEYPAGRLLRDAKLYEIGAGTSEIRRMLIGRELFNETK"
     PFAM_domain     4065..4394
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02771.18"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2522_0203"
                     /evalue="3.30E-39"
                     /label="ctg1_2522"
                     /locus_tag="ctg1_2522"
                     /protein_end="123"
                     /protein_start="13"
                     /score="134.1"
                     /tool="antismash"
                     /translation="IDMLRDSVHQFAQAELAPRAAQIDRDNEFPMDMWRKFGDMGLLGM
                     TVEEEYGGTNMGYLAHVVAMEEISRASASVGLSYGAHSNLCVNQIRKNGSEAQKQKYLP
                     KLCSGE"
     PFAM_domain     4404..4691
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02770.21"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2522_0204"
                     /evalue="2.20E-26"
                     /label="ctg1_2522"
                     /locus_tag="ctg1_2522"
                     /protein_end="222"
                     /protein_start="126"
                     /score="92.0"
                     /tool="antismash"
                     /translation="ALAMSEPNAGSDVVSMKLRAEKRGDRYVLNGNKMWITNGPDAHTY
                     VIYAKTDINAGSRGMTAFIVERGYKGFSRHQKLDKLGMRGSNTCELVFEDC"
     PFAM_domain     4725..5171
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00441.26"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2522_0205"
                     /evalue="4.50E-41"
                     /label="ctg1_2522"
                     /locus_tag="ctg1_2522"
                     /protein_end="382"
                     /protein_start="233"
                     /score="140.6"
                     /tool="antismash"
                     /translation="GAGVRVLMSGLDYERTVLSGGPTGIMSACMDVVLPYVHERQQFKQ
                     SIGEFQLVQGKLADMYAGMNASKSYLYNVAKACDRGEESRKDAAAVILYTAEMATKMAL
                     DTIQLLGGNGYTNEYPAGRLLRDAKLYEIGAGTSEIRRMLIGREL"
     CDS             5315..6922
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 515.7; E-value: 2.4e-156)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2523"
                     /transl_table=11
                     /translation="MAILHTQINPRSPEFAANQAAMLAQVNDLRALLARVHEGGGAKAQ
                     ERHTSRGKLLPRERINRLLDIGSPFLEVGQLAAHEVYGEDVPAAGVVAGIGRVEGVECM
                     IIANDATVKGGSYYPLTVKKHLRAQTIAQQNRLPCIYLVDSGGANLPRQEEVFPDREHF
                     GRIFFNQANMSAQGIPQIAVVMGSCTAGGAYVPAMSDETIMVRNQATIFLAGPPLVKAA
                     TGEVVTAEELGGADVHCKTSGVADHYADDDEHALALARRCIANLNWRKLGQLQARAPIA
                     PLHAADELYGVIPADAKQPFDVREVIARIVDGSEFDEFKALFGTTLVCGFAHVHGYPVA
                     ILANNGILFAEAAQKGAHFIELACQRGIPLLFLQNITGFMVGKKYEEGGIAKHGAKLVT
                     AVACAKVPKFTVIIGGSFGAGNYGMCGRAYDPRFLWMWPNARIGVMGAEQAAGVLVQVK
                     REQAARAGHPFSDEEETRIKQPIVAQYEQQAHAYYSSARLWDDGVIDPAQTRDVLGLAL
                     SASLNAPIKPTQFGVFRM"
     PFAM_domain     5456..6889
                     /aSDomain="Carboxyl_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01039.24"
                     /description="Carboxyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2523_0206"
                     /evalue="7.10E-159"
                     /label="ctg1_2523"
                     /locus_tag="ctg1_2523"
                     /protein_end="525"
                     /protein_start="47"
                     /score="529.7"
                     /tool="antismash"
                     /translation="HTSRGKLLPRERINRLLDIGSPFLEVGQLAAHEVYGEDVPAAGVV
                     AGIGRVEGVECMIIANDATVKGGSYYPLTVKKHLRAQTIAQQNRLPCIYLVDSGGANLP
                     RQEEVFPDREHFGRIFFNQANMSAQGIPQIAVVMGSCTAGGAYVPAMSDETIMVRNQAT
                     IFLAGPPLVKAATGEVVTAEELGGADVHCKTSGVADHYADDDEHALALARRCIANLNWR
                     KLGQLQARAPIAPLHAADELYGVIPADAKQPFDVREVIARIVDGSEFDEFKALFGTTLV
                     CGFAHVHGYPVAILANNGILFAEAAQKGAHFIELACQRGIPLLFLQNITGFMVGKKYEE
                     GGIAKHGAKLVTAVACAKVPKFTVIIGGSFGAGNYGMCGRAYDPRFLWMWPNARIGVMG
                     AEQAAGVLVQVKREQAARAGHPFSDEEETRIKQPIVAQYEQQAHAYYSSARLWDDGVID
                     PAQTRDVLGLALSASLNAPI"
     CDS             7031..7825
                     /NRPS_PKS="Domain: ECH (14-255). E-value: 1.1e-44. Score:
                     144.4. Matches aSDomain: nrpspksdomains_ctg1_2524_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 202.7; E-value:
                     9e-62)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2524"
                     /transl_table=11
                     /translation="MTDFTTVQLEKDPRGFATLWLNRPEKNNAFNAEMIRELILALDTI
                     TADKTLRFLLLRGRGRHFSAGADLAWMQASAKLDYNANLNDARELAELMYNLNGLKIPT
                     LAVVQGAAFGGAVGLVSCCDMAIGAEDALFSLSEVRIGLAPAVISPFVVQALGERAARR
                     YALTAERFSGSRARELGLLAEAYPAAELDAQVESWVSNLLLNSPQAMQASKDLLREVAS
                     GVLSPNLRRYTENAIARIRVSPEGQEGLNAFLEKRTPAWQEQ"
     aSDomain        7073..7795
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2524_ECH.1"
                     /evalue="1.10E-44"
                     /label="ctg1_2524_ECH.1"
                     /locus_tag="ctg1_2524"
                     /protein_end="255"
                     /protein_start="14"
                     /score="144.4"
                     /tool="antismash"
                     /translation="GFATLWLNRPEKNNAFNAEMIRELILALDTITADKTLRFLLLRGR
                     GRHFSAGADLAWMQASAKLDYNANLNDARELAELMYNLNGLKIPTLAVVQGAAFGGAVG
                     LVSCCDMAIGAEDALFSLSEVRIGLAPAVISPFVVQALGERAARRYALTAERFSGSRAR
                     ELGLLAEAYPAAELDAQVESWVSNLLLNSPQAMQASKDLLREVASGVLSPNLRRYTENA
                     IARIRVSPEGQEGLNAFLE"
     PFAM_domain     7073..7822
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2524_0207"
                     /evalue="1.00E-48"
                     /label="ctg1_2524"
                     /locus_tag="ctg1_2524"
                     /protein_end="264"
                     /protein_start="14"
                     /score="165.9"
                     /tool="antismash"
                     /translation="GFATLWLNRPEKNNAFNAEMIRELILALDTITADKTLRFLLLRGR
                     GRHFSAGADLAWMQASAKLDYNANLNDARELAELMYNLNGLKIPTLAVVQGAAFGGAVG
                     LVSCCDMAIGAEDALFSLSEVRIGLAPAVISPFVVQALGERAARRYALTAERFSGSRAR
                     ELGLLAEAYPAAELDAQVESWVSNLLLNSPQAMQASKDLLREVASGVLSPNLRRYTENA
                     IARIRVSPEGQEGLNAFLEKRTPAWQEQ"
     CDS             7905..9860
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     723.4; E-value: 4.8e-219)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2525"
                     /sec_met_domain="ATP-grasp (E-value: 1.6e-10, bitscore:
                     38.7, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRKHIDTLLVANRGEIACRVMRTAKAQGLKTVAVHSAIDAGARH
                     VREADMAVNLGGAKPADSYLLIDKIIAAAKASGAQAIHPGYGFLSENAGFARAIEAAGL
                     VFLGPPASAIDAMGSKSAAKALMEDAGVPLVPGYHGEAQDVETFRVAAERIGYPVLLKA
                     AAGGGGKGMKVVERESELAETLASAQREAQSAFGDSRMLVEKYVLQPRHVEIQVFADSH
                     GNCLYLNERDCSIQRRHQKVVEEAPAPGLSPELRRAMGEAAVKAAQAIGYVGAGTVEFL
                     LDARGQFFFMEMNTRLQVEHPVTEAITGLDLVAWQIRVARGEALPITQEQVPLNGHAIE
                     VRLYAEDTDNDFLPASGDLKLYREPAAGEGRRVDSGVVEGDTVSPFYDPMLAKLVAWGE
                     DREQARQRLLAMLDETAVGGFASNLPFLRRVLAHPAFAAAELDTGFIARHQQQLLPAIT
                     ELPGEFWQLAAEAWLQSEVPSRAHEDYYSPWGSHSGWRAGLASETDLHLSCGEQRSTVH
                     LRGAQHSRLQGEQLWIEQDGLRRAHRAIRRGDTLHLEWHGKLHEVRRIDPIAEVEASHA
                     QHGGLTAPMNGSIVRVLVEPGQAVEAGAALVVLEAMKMEHSIRAPHAGTVKALYCGEGD
                     MVSEGAALVELEEIPA"
     PFAM_domain     7920..8246
                     /aSDomain="Biotin_carb_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00289.24"
                     /description="Biotin carboxylase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2525_0208"
                     /evalue="1.40E-40"
                     /label="ctg1_2525"
                     /locus_tag="ctg1_2525"
                     /protein_end="114"
                     /protein_start="5"
                     /score="138.3"
                     /tool="antismash"
                     /translation="IDTLLVANRGEIACRVMRTAKAQGLKTVAVHSAIDAGARHVREAD
                     MAVNLGGAKPADSYLLIDKIIAAAKASGAQAIHPGYGFLSENAGFARAIEAAGLVFLGP
                     PASAI"
     PFAM_domain     8262..8882
                     /aSDomain="CPSase_L_D2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02786.19"
                     /description="Carbamoyl-phosphate synthase L chain, ATP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2525_0209"
                     /evalue="4.10E-81"
                     /label="ctg1_2525"
                     /locus_tag="ctg1_2525"
                     /protein_end="326"
                     /protein_start="119"
                     /score="271.6"
                     /tool="antismash"
                     /translation="KSAAKALMEDAGVPLVPGYHGEAQDVETFRVAAERIGYPVLLKAA
                     AGGGGKGMKVVERESELAETLASAQREAQSAFGDSRMLVEKYVLQPRHVEIQVFADSHG
                     NCLYLNERDCSIQRRHQKVVEEAPAPGLSPELRRAMGEAAVKAAQAIGYVGAGTVEFLL
                     DARGQFFFMEMNTRLQVEHPVTEAITGLDLVAWQIRVARGEALP"
     PFAM_domain     8922..9245
                     /aSDomain="Biotin_carb_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02785.21"
                     /description="Biotin carboxylase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2525_0210"
                     /evalue="3.60E-36"
                     /label="ctg1_2525"
                     /locus_tag="ctg1_2525"
                     /protein_end="447"
                     /protein_start="339"
                     /score="123.6"
                     /tool="antismash"
                     /translation="EVRLYAEDTDNDFLPASGDLKLYREPAAGEGRRVDSGVVEGDTVS
                     PFYDPMLAKLVAWGEDREQARQRLLAMLDETAVGGFASNLPFLRRVLAHPAFAAAELDT
                     GFIA"
     PFAM_domain     9645..9842
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00364.24"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2525_0211"
                     /evalue="3.00E-17"
                     /label="ctg1_2525"
                     /locus_tag="ctg1_2525"
                     /protein_end="646"
                     /protein_start="580"
                     /score="62.3"
                     /tool="antismash"
                     /translation="LTAPMNGSIVRVLVEPGQAVEAGAALVVLEAMKMEHSIRAPHAGT
                     VKALYCGEGDMVSEGAALVEL"
     CDS             10001..10897
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 233.6;
                     E-value: 7.6e-71)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2526"
                     /sec_met_domain="HMGL-like (E-value: 1.3e-54, bitscore:
                     183.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLPQHVRLVEVGPRDGLQNEKQPISVADKVRLTDDLSAAGLSYI
                     EVGSFVSPKWVPQMAGSAEVFAGIQYKPGVVYGALTPNLKGFEAAVEAGVKEVAVFAAA
                     SEAFSQKNINCSIAESLERFVPVMEAAKAHGITVRGYVSCVLGCPYEGEVAPEQVAAVA
                     RELLAMGCYEVSLGDTIGTGTAGKTRTLFEVVGRDIPRDKLAGHFHDTYGQALANIYAS
                     LLEGVAVFDSSVAGLGGCPYAKGATGNVATEDVLYLLNGLGIATGIDMDKLIAAGQRIC
                     EVLGKPNGSRVARARQA"
     PFAM_domain     10019..10834
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2526_0212"
                     /evalue="5.10E-54"
                     /label="ctg1_2526"
                     /locus_tag="ctg1_2526"
                     /protein_end="278"
                     /protein_start="6"
                     /score="183.7"
                     /tool="antismash"
                     /translation="VRLVEVGPRDGLQNEKQPISVADKVRLTDDLSAAGLSYIEVGSFV
                     SPKWVPQMAGSAEVFAGIQYKPGVVYGALTPNLKGFEAAVEAGVKEVAVFAAASEAFSQ
                     KNINCSIAESLERFVPVMEAAKAHGITVRGYVSCVLGCPYEGEVAPEQVAAVARELLAM
                     GCYEVSLGDTIGTGTAGKTRTLFEVVGRDIPRDKLAGHFHDTYGQALANIYASLLEGVA
                     VFDSSVAGLGGCPYAKGATGNVATEDVLYLLNGLGIATGIDMDKLIAAGQ"
     CDS             11206..13161
                     /NRPS_PKS="Domain: AMP-binding (94-525). E-value: 5.3e-51.
                     Score: 165.3. Matches aSDomain:
                     nrpspksdomains_ctg1_2527_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     166.5; E-value: 1.3e-50)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2527"
                     /sec_met_domain="AMP-binding (E-value: 3e-56, bitscore:
                     188.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQPLWAPSAERIAATRMDAFRRFVNQRHTLQLADYPALHAWSVA
                     QRETFWQAIVDFFEVRFTQQPDAVLREGPAMPSAHWFPGATLNFAEHLLRRRDHHPALV
                     AIGEDGSREQLSYAELATHVAGLQQSLKAAGVGIGDRVAAFMPNTWQTVVGMLATASLG
                     ATWSSCSPDFGTQGVIDRFGQIEPKVLIAAAGYRYAGKNLDLTAKLNEILERLPSLQQL
                     VVVPYSNPTAGAGDFRSAARVSLWQDFYQAGGEPKFTPVSFEQPLYILYSSGTTGVPKC
                     IVHGVGGTLLQHVKELGLHTDLTADDTLFYYTTCGWMMWNWLVSGLALGASLVLFDGSP
                     FHPGAERLIDLIDAENISLFGTSAKFIAALEKAGAKPRETHRLRRLKAILSTGSPLAHE
                     SFEYVYRDIKSDVCLSSISGGTDIVSCFALGNPTLPVWRGELQCKGLGMDVQVWNEAGQ
                     PVIAEKGELVCARHFPSMPVGFWKDADGEKFRSAYFDTFPGVWAHGDYAEITEHDGLVI
                     HGRSDAVLNPGGVRIGTAEIYRQVEKVEQVLESIAIGQDWEGDVRVVLFVRLRDGVALS
                     DELQAQIRQVIRANTTPRHVPAKIIAVADIPRTISGKIVELAVRNVVHGKPVKNTDALA
                     NPQALELYRDLPQLQS"
     aSDomain        11209..13158
                     /aSDomain="TIGR01217"
                     /aSTool="tigrfam"
                     /description="ac_ac_CoA_syn: acetoacetate-CoA ligase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2527_0050"
                     /evalue="7.20E-274"
                     /identifier="TIGR01217"
                     /label="ctg1_2527"
                     /locus_tag="ctg1_2527"
                     /protein_end="651"
                     /protein_start="1"
                     /score="907.8"
                     /tool="antismash"
                     /translation="QQPLWAPSAERIAATRMDAFRRFVNQRHTLQLADYPALHAWSVAQ
                     RETFWQAIVDFFEVRFTQQPDAVLREGPAMPSAHWFPGATLNFAEHLLRRRDHHPALVA
                     IGEDGSREQLSYAELATHVAGLQQSLKAAGVGIGDRVAAFMPNTWQTVVGMLATASLGA
                     TWSSCSPDFGTQGVIDRFGQIEPKVLIAAAGYRYAGKNLDLTAKLNEILERLPSLQQLV
                     VVPYSNPTAGAGDFRSAARVSLWQDFYQAGGEPKFTPVSFEQPLYILYSSGTTGVPKCI
                     VHGVGGTLLQHVKELGLHTDLTADDTLFYYTTCGWMMWNWLVSGLALGASLVLFDGSPF
                     HPGAERLIDLIDAENISLFGTSAKFIAALEKAGAKPRETHRLRRLKAILSTGSPLAHES
                     FEYVYRDIKSDVCLSSISGGTDIVSCFALGNPTLPVWRGELQCKGLGMDVQVWNEAGQP
                     VIAEKGELVCARHFPSMPVGFWKDADGEKFRSAYFDTFPGVWAHGDYAEITEHDGLVIH
                     GRSDAVLNPGGVRIGTAEIYRQVEKVEQVLESIAIGQDWEGDVRVVLFVRLRDGVALSD
                     ELQAQIRQVIRANTTPRHVPAKIIAVADIPRTISGKIVELAVRNVVHGKPVKNTDALAN
                     PQALELYRDLPQLQS"
     PFAM_domain     11311..11478
                     /aSDomain="ACAS_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16177.7"
                     /description="Acetyl-coenzyme A synthetase N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2527_0213"
                     /evalue="3.70E-10"
                     /label="ctg1_2527"
                     /locus_tag="ctg1_2527"
                     /protein_end="91"
                     /protein_start="35"
                     /score="39.6"
                     /tool="antismash"
                     /translation="YPALHAWSVAQRETFWQAIVDFFEVRFTQQPDAVLREGPAMPSAH
                     WFPGATLNFAE"
     aSDomain        11488..12780
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2527_AMP-binding.1"
                     /evalue="5.30E-51"
                     /label="ctg1_2527_AMP-binding.1"
                     /locus_tag="ctg1_2527"
                     /protein_end="525"
                     /protein_start="94"
                     /score="165.3"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="RRRDHHPALVAIGEDGSREQLSYAELATHVAGLQQSLKAAGVGIG
                     DRVAAFMPNTWQTVVGMLATASLGATWSSCSPDFGTQGVIDRFGQIEPKVLIAAAGYRY
                     AGKNLDLTAKLNEILERLPSLQQLVVVPYSNPTAGAGDFRSAARVSLWQDFYQAGGEPK
                     FTPVSFEQPLYILYSSGTTGVPKCIVHGVGGTLLQHVKELGLHTDLTADDTLFYYTTCG
                     WMMWNWLVSGLALGASLVLFDGSPFHPGAERLIDLIDAENISLFGTSAKFIAALEKAGA
                     KPRETHRLRRLKAILSTGSPLAHESFEYVYRDIKSDVCLSSISGGTDIVSCFALGNPTL
                     PVWRGELQCKGLGMDVQVWNEAGQPVIAEKGELVCARHFPSMPVGFWKDADGEKFRSAY
                     FDTFPGVWAHGDYAEITEHDGLVIHGRSDAVL"
     PFAM_domain     11491..12780
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2527_0214"
                     /evalue="5.60E-44"
                     /label="ctg1_2527"
                     /locus_tag="ctg1_2527"
                     /protein_end="525"
                     /protein_start="95"
                     /score="150.5"
                     /tool="antismash"
                     /translation="RRDHHPALVAIGEDGSREQLSYAELATHVAGLQQSLKAAGVGIGD
                     RVAAFMPNTWQTVVGMLATASLGATWSSCSPDFGTQGVIDRFGQIEPKVLIAAAGYRYA
                     GKNLDLTAKLNEILERLPSLQQLVVVPYSNPTAGAGDFRSAARVSLWQDFYQAGGEPKF
                     TPVSFEQPLYILYSSGTTGVPKCIVHGVGGTLLQHVKELGLHTDLTADDTLFYYTTCGW
                     MMWNWLVSGLALGASLVLFDGSPFHPGAERLIDLIDAENISLFGTSAKFIAALEKAGAK
                     PRETHRLRRLKAILSTGSPLAHESFEYVYRDIKSDVCLSSISGGTDIVSCFALGNPTLP
                     VWRGELQCKGLGMDVQVWNEAGQPVIAEKGELVCARHFPSMPVGFWKDADGEKFRSAYF
                     DTFPGVWAHGDYAEITEHDGLVIHGRSDAVL"
     CDS_motif       12007..12054
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2527_0001"
                     /evalue="2.00E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_2527"
                     /protein_end="283"
                     /protein_start="267"
                     /score="17.4"
                     /tool="antismash"
                     /translation="YILYSSGTTGVPKCIV"
     misc_feature    12184..12186
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     PFAM_domain     12832..13044
                     /aSDomain="AMP-binding_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13193.8"
                     /description="AMP-binding enzyme C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2527_0215"
                     /evalue="2.10E-05"
                     /label="ctg1_2527"
                     /locus_tag="ctg1_2527"
                     /protein_end="613"
                     /protein_start="542"
                     /score="25.5"
                     /tool="antismash"
                     /translation="KVEQVLESIAIGQDWEGDVRVVLFVRLRDGVALSDELQAQIRQVI
                     RANTTPRHVPAKIIAVADIPRTISGK"
     CDS             13245..13985
                     /locus_tag="ctg1_2528"
                     /transl_table=11
                     /translation="MQVVFCLLVALLYVGGVAADEPLALHMPDAPPLTLYHDERGHGMV
                     GDITLAAITLSGRTARIVDEPWARAQVNVASGQNQLIIPLSRTPEREQRYTWIVPIMPL
                     ERAFFSLDKPVSSFAQARQRYRRICVGLGTAQVEILRREGFADEQIIQLKLGENPAILL
                     ERGRLDAWFTGIPEALYIWHKSAEQRRKLYQSPVLASTDLYLACSRICAPQIVEQLRAA
                     VLQLEASGVSPRLRQAYLPELDRR"
     PFAM_domain     13332..13964
                     /aSDomain="SBP_bac_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00497.22"
                     /description="Bacterial extracellular solute-binding
                     proteins, family 3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2528_0216"
                     /evalue="1.80E-11"
                     /label="ctg1_2528"
                     /locus_tag="ctg1_2528"
                     /protein_end="240"
                     /protein_start="29"
                     /score="44.0"
                     /tool="antismash"
                     /translation="APPLTLYHDERGHGMVGDITLAAITLSGRTARIVDEPWARAQVNV
                     ASGQNQLIIPLSRTPEREQRYTWIVPIMPLERAFFSLDKPVSSFAQARQRYRRICVGLG
                     TAQVEILRREGFADEQIIQLKLGENPAILLERGRLDAWFTGIPEALYIWHKSAEQRRKL
                     YQSPVLASTDLYLACSRICAPQIVEQLRAAVLQLEASGVSPRLRQAYL"
     CDS             14108..14449
                     /locus_tag="ctg1_2529"
                     /transl_table=11
                     /translation="MDVVKTLKPGKPGTKRLQERYGEQLVAVRYRLDRKTNTHYTTVEL
                     IVEQKYALYKTPPPAPTPPVALRIFRHENDLQRLIRSAGGKWDRENQVWLIERSEAERL
                     GLAERIIWT"
     CDS             15024..15629
                     /locus_tag="ctg1_2530"
                     /transl_table=11
                     /translation="MKKTVLILVPALLLSGCGDPEFHYQNGDESKNITLRIPKNYINYF
                     PGVKYEKDGPVVIRFSYPQLEPLTKALPEEQKVTVSISHLSSLELTTQETRNPYCETDK
                     KWKLLQAAGIHGEFYKFIGKSPGSASADITYKPIKKTLGLYCITCVENANCEIHAVSSQ
                     GISYSAFYTEDLMPDKWHSIYMAVDKILSKFTASSKGI"
     misc_feature    15057..15059
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15276..15278
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15546..15548
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             16127..16933
                     /locus_tag="ctg1_2531"
                     /transl_table=11
                     /translation="MKVLASPDFNAKVPALNTETISSLSAFISSAEQYEKNDFILKNVN
                     SMSLLDGDIYSAKINSSRLYFTIGADEQGDYLLLLDIAALQTAPSVKSSAFFTTNNPKT
                     NSSLNPKLNSAINPKLNSAINPKLNSAINPKLNSAINPKLNSAINPKLNSAINPKLNSA
                     INPKLNSAINPKLNSSLNPRLNRSYGGPYLYDANLNQEAYSVRANNKIEILFNSGGDFY
                     GFLVSANDRVKIEFDTGNTWTGYYVKANEKVWLRYSLNNEWLGLLV"
     misc_feature    16364..16366
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16508..16510
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16916..16918
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             22245..22838
                     /locus_tag="ctg1_2532"
                     /transl_table=11
                     /translation="MPNLTLHRGEKNNWWPAPEVRLICGMTLYGPWQPTAVSSLWNTLK
                     NEVKGALGTSLEKKVAAYAQYLRATGRPFALATAWTEVGSFTSDYNYVIRIPNAHFFYW
                     GGTKDAPDLGAAAAWTTPEQVTADFIVLNAPTVAASTILGFGHHTGTREITFFHDLPIG
                     LIESCNGRPITDYAIKSKSDLSFDERIKYAKYLR"
ORIGIN
        1 aaggcggaac gaatctcacc ggacagcagc ggctccagcc actgcttctt ctgcgcctcg
       61 ctggcgtaac gcaccagggt ctccatgttg ccggtgtccg gcgcggagca gttgaacggc
      121 tcggcgccga tcagcgagcg gcccatgatc tcggccagcg gtgcgtattc catgttggtc
      181 aggccggcgc cgtactcgga ttccggcagg aacaggttcc acagcccctc ggccttcgcc
      241 ttggctttca gctcctccat gatcgcggtc ggctgccagc ggtcaccctc gttgacctgc
      301 tcttcgaaca cggcttcggc cgggtagaca taggcttcca tgaacgcggt gacgcgctca
      361 cgcagttcct gaaccttggg ggaataggcg aaatccatgg ggacaccttg gtggttggct
      421 tcgatgtgga atgatgctag aacagcaccc acgatttatc taagctattt tcctgcctta
      481 tcaacattca taagcaatat gagataaggc ttgaagcacg gagaagacca tgaatctgaa
      541 caaggtagac ctcaacctct tcatcgtctt cgacgctatc tataccgagg ccaacctgac
      601 ccgcgccggg cagatcgtcg gcatcactca gccggctgta tccaacgccc tggcgcgcct
      661 gcgcgagacc ttcaacgacc cgctgttcgt gcgcaccgcg cagggcatgg tgcccacgcc
      721 catggcacag aacatcatcg gcccggtacg caacgcgctg cagctgctgc gcgtgtcggt
      781 gcaggagagt cgcaccttcg atgccaagca ggcgaacaag acctaccgca tcagcatgac
      841 cgacctctcc gagcagatcc tcctgccgcc gctgttccag cgcctgcgcc gcctggcacc
      901 ggcggtgcag atcgaaagct tccaggccaa gcgccgcgaa accaccaagg aactggccgc
      961 cggccgcctg gacttcgccg tcgacgcgcc gctcaacacc gacccgcagg tgcgccacgt
     1021 caagctgatg gaagaccgct acgtctgcgc catgcgcccc ggtcacccgc tggccaagga
     1081 caagctgagc ctggacgagt acctgtcgca ggcgcacatc cagatttcca gccgccgcag
     1141 cggcctcggc tacatcgacc tgtcgctggg caagatgggc ctgcaacgca aggtggcgct
     1201 gcgctcgcag cactacctga tggcctccag cgtgctgcac agcaccgaca tgctgatgac
     1261 cgtgccggag cgcttcgccc gtcgccacaa cctgcaccac gtcgacctgc cggtcagcga
     1321 cgtaccggcc ctggagactc acctgtactg gcacgaaagc accgaccagg acccggccaa
     1381 ccgctggatg cgcgagcaac tgatcgaact ggcgcagcag atcagcgccc aggagaaaaa
     1441 ggctgccgag cccgcctgag cccacttatc cctctcccgc cgcgttctcc ctctccctct
     1501 gggagagggc cggggtgagg gtgccgcagg caactcgatg cagacctaaa caccctcacc
     1561 ctacgcgggc cgccctaccc cctctcccag aaagccgcaa cccgcctaca agctgcgcgc
     1621 aatcaccatc cgctgcacat cactggtgcc ttcatagatc tggcacacgc gcacatcgcg
     1681 gtagatgcgc tccaccggga agtccttgag gtagccgtag ccgcccagcg tctggatcgc
     1741 cgccgagcaa accttctcgg ccatctccga ggcgaacagc ttggccatcg acgcctcagt
     1801 caggcacggc tggccggctt cgcgcaggct ggcggcgtga tgcaccatct gccgcgccac
     1861 ggcgatctgc gtggccatgt cggccaggcg gaaggccacc gcctgatgct cgatgatcgg
     1921 cttgccgaag gtctgccgct cgcaggcgta gtcgcgggcc gcctcgaatg cggcgcgggc
     1981 catgcccacc gactgcgcgg caatgccgat gcgcccgcct tccaagttgc tcagggcaat
     2041 gcggtaaccc tcgccctcct cgcccaggcg cagcgacgcc ggaatacgca cctcgtcgag
     2101 ctggatctgg caggtgtccg aggcatgctg gccgagcttg tcctccaccc gcaccaccga
     2161 atagccgggc gtgtcagtcg gcacgatgaa ggcgctgata cccttcttgc cggccgcagg
     2221 gtcggtcacg gcgaatacga tcaccattcc ggcgtggctg ccggaggtga tgaactgctt
     2281 ggcgccgctg agcacatagt ggtcgccgtc acgccgcgcg cgggtgcgta ggtcgctggc
     2341 gtcggagccg gcctgtggct cggtgagggc gaaggcaccg agcatggcgc cgctggccag
     2401 gggctggagg aagcgctgtt tctgctcctg actgccgaac ttgaggatgg gcatgcagcc
     2461 caccgagttg tgcacgctca tgatggtcga gcaggcgccg tcgccggcgg cgatctcctc
     2521 cagggccatg gcgtaggcca ggtggccggt ttgcgcgccg ccccactcct ccggcaccag
     2581 catgccgagg aaaccgaggt cggccatctc cttcaaggct tctgccggga agcggtgctc
     2641 gcggtcccag tcggcggcaa agggcttcag ccgctcctgg gcgaactgac gggccatgtc
     2701 acggatcagg atgtcctgtt cggcgggaat catcggctca cctcacttgg cggccatgcg
     2761 cagcgcgcca tccagacgga tggtctcgcc gttgagcatg gcgttctcga cgatatgccg
     2821 gaccagtgcg gcgtactcgg ccgggcgtcc caggcgcggc gggaacggca cgttggcagc
     2881 cagggagtcc tgcacctcct ggggcatgcc ggccatcatc ggcgtctcga agatgcccgg
     2941 ggcgatgcac atcacgcgga tgccggagcg tgccagatcg cgcgccgccg gcagggtcat
     3001 ggcggcgacg ccccccttgg acgccgaata ggcgcactgg cccatctgcc catcgaaggc
     3061 cgccaccgag gcggtgttga tgatcactcc acgctcgcca ccctcgttcg gctggtttct
     3121 ggccatggcc tcggcggcca ggcgcagcat gttgaagctg ccgatcagat tgatctcgat
     3181 ggtgcggcgg aagctgtcca ggccgtgggc gccgttgcgc ccgataacct tctcggccgg
     3241 cgccacgccg gcgcagttga ccagcccatg cacggcacca aaagcctgca gagcctcttc
     3301 cacagcggcg cggccgtcgg cctcgctgct gatatcggca cgcaggaaac gcgcgcgctc
     3361 gcccagctcg gcggccgcct tggcgccggc ctcggcgttg atgtccagca gcagcacttt
     3421 agcgccctgc gccaccagct cccgcgcagt ggccaggcca aggccggagc caccgccggt
     3481 gatgaggaat acggagtctt cgatacgcat gcacagtcct cgaatcgatg aggcgtcggc
     3541 ccctgccgac attgacaggc agatttgcac aggtttacgt taacgtaaag gtaaacgaga
     3601 gccgcgcatg tccatcacct actccatctc cgatctggcc cgcgagctgg acgtcaccac
     3661 ccgcgccatt cgcttctacg aggagcaagg catgctggtg ccggagcggc gcggccagga
     3721 gcgcatctac cggcccaagg acctggtggc gctcaaactg atcctgcgtg gcaagcgcat
     3781 cggcttctcc ctggccgagt gcaaggaact gatcgacctc tacgacccca gcagcggcaa
     3841 ccgcaagcag ctggagacct tcatggccaa gatcgccgcc cgccgcgccc agctggaaca
     3901 gcagctgctc gacatccagc agatgcagct ggaactcgac accgccgagg agcgctgcct
     3961 ggccgcgctt gctgccaccg aatccgccgt ttcctgactc acaattacaa gacacaggtg
     4021 accccatgag ctacccaacc ctcaacttcg gtctcggcga gaccatcgac atgctgcgcg
     4081 actcggtgca tcagttcgcc caggccgagc tggccccgcg tgcggcgcag atcgaccgcg
     4141 acaacgagtt ccccatggac atgtggcgca agttcggcga catgggcctc ctcggcatga
     4201 ccgtggaaga ggaatacggc ggcaccaaca tgggctacct ggcccacgtg gtggcgatgg
     4261 aagagatcag ccgcgcctcg gcctcggtcg gcctgtccta tggcgcccac tccaacctgt
     4321 gcgtcaacca gatccgcaag aacggcagcg aggcgcagaa gcagaaatac ctacccaagc
     4381 tgtgctccgg cgagcacatc ggcgccctgg ccatgagcga gcccaacgcc ggctccgacg
     4441 tggtgtcgat gaagctgcgc gccgagaagc gtggcgaccg ttacgtgctc aacggcaaca
     4501 agatgtggat caccaacggc cccgacgcgc acacctatgt gatctacgcc aagaccgaca
     4561 tcaacgccgg ttcgcgcggc atgaccgcgt ttatcgtcga gcgcggctac aagggtttct
     4621 cccgccacca gaagctcgac aagctgggca tgcggggctc caacacctgc gagctggtgt
     4681 tcgaggactg cgaagtgccg gaggagaaca tcctcggcgc cgagggtgcc ggcgtgcgcg
     4741 tgctgatgag cggcctggac tacgagcgca ccgtgctctc cggcggcccg accgggatca
     4801 tgagcgcctg catggacgtg gtgctgccct acgtgcacga gcgccagcag ttcaagcagt
     4861 cgatcggcga gttccagctg gtgcagggca agctggccga catgtacgcc ggcatgaacg
     4921 cctccaaatc ctacctgtac aacgtggcca aggcctgcga ccgcggcgag gaatcgcgca
     4981 aggacgccgc cgcggtgatc ctctacaccg ccgagatggc taccaagatg gccctggaca
     5041 ccatccagct gctcggcggc aacggctaca ccaacgagta cccggccggc cgcctgctgc
     5101 gtgacgccaa gctgtacgag atcggcgccg gcaccagcga gatccgccgc atgctgatcg
     5161 gccgcgagct gttcaacgag acgaaataat ccttctcccc ctgggagaag gtgcccgaag
     5221 ggcggatgag ggagctctga ccagcaccct caccctacgc gggccgccca gccctctccc
     5281 agagggagag ggaatcaaag catacgaggc atacatggcc atcctgcaca cccagatcaa
     5341 cccccgttcg ccggagttcg ctgccaacca ggccgccatg ctcgcccagg tcaacgacct
     5401 gcgcgccctg ctcgcccgcg tccacgaagg cggcggcgcc aaggcccagg agcgccacac
     5461 ctcgcgcggc aagctgctgc cgcgcgagcg catcaaccgc ctgctggaca tcggttcgcc
     5521 cttcctcgaa gtcggccaac tggccgccca cgaggtgtac ggcgaggacg tgccggccgc
     5581 cggcgtggtc gccggtatcg gccgcgtcga gggcgttgag tgcatgatca tcgccaacga
     5641 cgccacggtg aagggcggca gctactaccc gctgaccgtg aagaagcacc tgcgtgcgca
     5701 gaccatcgcc cagcagaacc gcctgccgtg catctacttg gtggactccg gcggcgccaa
     5761 cctgccgcgt caggaagaag tgttccccga ccgcgagcac ttcggccgga tcttcttcaa
     5821 ccaggccaat atgagcgctc agggtatccc gcagatcgcc gtggtgatgg gctcctgcac
     5881 cgccggcggc gcctatgtgc cggcgatgag tgacgagacc atcatggtgc gcaaccaggc
     5941 cactatcttc ctggccggcc cgccgttggt aaaagccgcc actggcgagg tggtgaccgc
     6001 cgaggagctg ggcggtgccg atgtgcactg caagacctcc ggcgtggccg accattacgc
     6061 cgatgacgac gagcatgccc tagccctggc ccgccgctgc atagcgaacc tcaactggcg
     6121 caagctcggc caactgcagg cccgcgcgcc cattgccccg ctccacgcgg cggacgagct
     6181 gtacggggtg atcccggcgg acgccaagca accctttgat gtacgtgaag tgatcgcgcg
     6241 tatcgtcgac ggcagcgaat tcgatgagtt caaagctctg ttcggcacca ccctggtctg
     6301 cggcttcgcc catgtccacg gctaccccgt ggcaatcctg gcgaacaacg gcatcctctt
     6361 cgccgaggcc gcgcagaaag gcgcgcactt catcgaactg gcctgccagc gcggcatacc
     6421 gctgctgttc ctgcagaaca tcaccggctt catggttggc aagaaatacg aggaaggcgg
     6481 catcgccaag cacggcgcca agctggttac cgccgtggcc tgcgccaagg tgccgaagtt
     6541 caccgtgatc atcggcggca gcttcggcgc cggtaactac ggcatgtgcg gccgtgccta
     6601 cgacccacgc ttcctgtgga tgtggcccaa cgcgcggatc ggcgtgatgg gtgccgagca
     6661 ggccgccggt gtgctggtcc aggtcaagcg cgagcaggcc gcccgcgccg gccatccgtt
     6721 cagtgacgag gaagaaacgc gcatcaagca gcccatcgtc gcccagtacg aacagcaggc
     6781 ccacgcctac tactccagcg cccgcctgtg ggacgacggc gtgatcgacc cggcgcagac
     6841 ccgcgacgtc ctcggtctgg ccctgtccgc cagcctcaat gcgccgatca agccgaccca
     6901 gttcggtgtg ttcagaatgt aacccccctc tccctccggg agaggggccg ggggtgaggg
     6961 acggcttgaa gaacgccgac caccctcacc ccagccctct cccaggggga gagggagtta
     7021 aggagccgtc atgaccgact tcaccaccgt acagcttgag aaagacccgc gcggcttcgc
     7081 caccctatgg ctgaaccgtc cggagaagaa caacgccttc aatgccgaaa tgatccgcga
     7141 gctgatcctc gccctcgaca cgatcaccgc ggacaagacc ttgcgcttcc tgctgctgcg
     7201 cggccgtggc aggcacttct ccgccggcgc cgacctggcc tggatgcagg cgtcggccaa
     7261 gctcgactac aacgccaatc tgaatgacgc ccgcgagctg gcggagctga tgtacaacct
     7321 caacggcctg aagatcccga ccctggccgt ggtccagggc gcggccttcg gcggcgcggt
     7381 gggcctggtc agttgctgcg acatggccat cggcgccgag gatgcactgt tcagcctgtc
     7441 cgaagtgcgc atcggcctgg ccccggcggt gatcagcccc ttcgtggtcc aggccctcgg
     7501 tgagcgcgcc gcgcgccgct atgcgctgac cgccgaacgt ttctccggca gccgcgcccg
     7561 cgagctgggc ctgctggccg aggcctatcc ggccgcggaa ctggacgccc aggtcgagag
     7621 ctgggtcagc aacctgctgc tcaacagccc gcaggccatg caggccagca aggacctgct
     7681 gcgcgaagtg gccagcggcg tgctcagccc caacctgcgc cgctacaccg agaacgccat
     7741 cgcccgcatc cgcgtcagcc ccgaaggcca ggagggactc aacgccttcc tggaaaaacg
     7801 cacgcccgcc tggcaggagc aataagtatg atgattccct ccttgcacgc cctgctcggc
     7861 aaagcgctgg ataaacgttc aaacctccgg caggagccgc aagcatgagc cgcaagcata
     7921 tcgacaccct gctggtcgcc aaccgcggcg agatcgcctg ccgggtgatg cgcaccgcca
     7981 aggcccaggg cctgaagacc gtggccgtgc acagcgccat cgacgccggc gcccgccatg
     8041 tgcgtgaagc cgatatggcg gtaaacctcg gcggcgccaa gccggccgac agctacctgc
     8101 tgatcgacaa gatcatcgcc gcggcgaagg ccagcggcgc ccaggccatc cacccgggct
     8161 acggcttcct ctccgagaac gccggcttcg cccgcgccat cgaggccgcc ggcctggtgt
     8221 tcctcggccc gcccgcctcc gccatcgacg ctatgggcag caagtcggcg gccaaggcgc
     8281 tgatggaaga cgccggcgtg ccgctggtgc ccggttacca cggcgaagcc caggacgtgg
     8341 aaaccttccg cgtcgccgcc gaacgcatcg gctacccggt gctgctcaag gccgctgccg
     8401 gtggcggtgg caagggcatg aaagtggtcg agcgcgagag cgaactggcc gaaaccctgg
     8461 cctctgccca gcgcgaagcc caatccgcct tcggcgactc gcgcatgctg gtggaaaaat
     8521 acgtgctgca gccgcgccac gtggagatcc aggtattcgc cgacagccac ggcaactgcc
     8581 tgtacctcaa cgagcgcgac tgctcgatcc agcgccgcca ccagaaggtg gtcgaggaag
     8641 ccccggctcc gggcctgagc cccgagctgc gccgcgccat gggcgaggcg gcggtcaagg
     8701 ccgcgcaggc catcggctat gtcggcgccg gcaccgtgga gttcctgctg gatgcccgcg
     8761 gccagttctt cttcatggaa atgaacaccc gcctgcaggt ggagcatccg gttaccgagg
     8821 ccatcactgg cctcgacctg gtggcctggc agattcgcgt cgcccgtggc gaggcgctgc
     8881 cgatcaccca ggaacaggtg ccgctgaatg gccacgccat cgaagtgcgc ctatacgccg
     8941 aggacaccga caacgacttc ctgcccgcct ccggcgacct caagctgtac cgcgaaccgg
     9001 ccgctggcga agggcgccgg gtagacagcg gcgttgtcga gggcgacacc gtctcgccct
     9061 tctacgaccc catgctggcc aagctggtcg cctggggcga ggatcgcgag caggcccgcc
     9121 agcgtctgct ggccatgctc gacgagaccg ccgtcggcgg cttcgccagc aacctgccct
     9181 tcctgcgccg cgtgctggcc catccggcct tcgctgctgc cgagctggac accggtttta
     9241 tcgcccggca tcagcaacag ctgctgccgg ccatcaccga gctgcccggc gaattctggc
     9301 aactggccgc cgaggcctgg ctgcagagcg aagtgcccag ccgcgcgcac gaggactatt
     9361 actcgccttg gggcagtcac tctggctggc gcgcgggatt ggccagtgaa accgacctgc
     9421 acctgagctg cggtgagcag cgcagcaccg tgcacctgcg cggcgcgcag cacagccgct
     9481 tgcagggcga gcagctgtgg attgagcagg acggcctgcg ccgcgcccac cgcgccatcc
     9541 gtcgtggcga tacgctgcac ctggaatggc acggcaagct gcatgaagtg cggcgtatcg
     9601 accccatcgc cgaggtcgag gccagccacg cccagcacgg cgggctgaca gccccgatga
     9661 acggcagtat cgtccgcgtc ctggtcgaac ccggccaggc cgtggaagcc ggcgcggccc
     9721 tggtggtact ggaagccatg aagatggaac acagcatccg cgcgccccac gccggcacgg
     9781 tcaaggcgct gtactgtggc gaaggcgaca tggtcagcga aggcgccgca ttggtagagc
     9841 tggaagaaat ccctgcctag cacggacagt tccctctccc tccgggagag ggttagggtg
     9901 agggacattg ccgggccgat ccgcccctca ccctacgcgg gccgccccgc cctctcccgt
     9961 gggaataggg gggcgtcaaa ccaatcttgt gaggaacttc atgaacctgc cgcaacacgt
    10021 ccgcctggtc gaagtcggcc cgcgcgacgg cctgcagaac gagaaacaac cgatcagcgt
    10081 ggccgacaag gtgcgtctga ccgacgacct gagcgccgcc ggcctgagct acatcgaagt
    10141 gggcagcttc gtctcgccca agtgggtgcc gcagatggcc ggcagcgccg aagtattcgc
    10201 cggtatccag tacaagcccg gcgtggtcta cggcgccctc acccccaacc tcaagggctt
    10261 cgaggctgcc gtggaagcag gagttaagga agtcgcggta tttgccgctg cctccgaggc
    10321 cttctcgcag aagaacatca actgctctat cgccgaaagc ctggagcgct tcgtgccggt
    10381 gatggaagcg gccaaggccc acggcatcac cgtgcgcggc tatgtctcct gcgtgctcgg
    10441 ttgcccctac gagggcgaag tcgcgcccga gcaggtcgcc gcggtcgcac gtgagctgct
    10501 ggccatgggc tgctacgaag tctcgctggg cgacaccatc ggcaccggta ccgccggcaa
    10561 gacccgcacc ctgttcgagg tggtcggccg cgatatcccg cgcgacaagc tggccgggca
    10621 cttccacgac acctacggcc aggccctggc caacatctac gccagcctgc tggaaggcgt
    10681 cgccgtgttc gacagctcgg tcgcaggcct gggcggctgc ccctatgcca agggtgctac
    10741 cggcaatgtc gccaccgagg acgtgctcta tctgctcaac ggcctgggca tagcaaccgg
    10801 catcgatatg gacaagctca tcgctgccgg acaacgcatc tgcgaggtac tcggcaagcc
    10861 caacggctcg cgggtggcca gggccagaca ggcttagcca aggcaggcac ggacagtccc
    10921 ctctcccatt tatgggagag ggctagggag agggaaagcg ctcgagtagc ccggatgcaa
    10981 tccggggaga aaccacccac acctaaccct gtcagctttt cctgacaggc tgtaaagcgc
    11041 gcagcgcccg ccatcgctgc accgtagtgc ccacgccaca gcggcgtagc tcaaaggcag
    11101 gccgaccgac ggcagcggct atggccgcct ccggacaaca ctttaggctg tgccatccgt
    11161 cgcctccggg ctggcgcgaa tgacaagaac catcgaggaa tcgagatgca acaaccgctc
    11221 tgggcgccct ccgccgaacg catcgccgcc acgcgcatgg atgccttccg ccgcttcgtc
    11281 aaccagcgcc acaccctgca actggccgac taccctgccc tgcatgcctg gagcgtggcg
    11341 cagcgcgaga cgttctggca ggccatcgtc gatttcttcg aggtgcgttt cacccagcag
    11401 cccgacgcgg tactgcgcga aggcccggcc atgcccagcg cccactggtt ccccggcgcc
    11461 accctgaact tcgccgagca cctgctgcgc cgccgcgacc accacccggc gctggtcgcc
    11521 attggcgagg acggttcgcg cgagcagctc tcctatgccg aactggccac gcatgtcgcc
    11581 ggcctgcaac agagcctcaa ggccgccggt gtcggcatcg gcgaccgcgt ggccgccttt
    11641 atgcccaaca cctggcagac ggtggtcggc atgctcgcca ccgccagcct cggcgccacc
    11701 tggtcgtcct gctcgccgga cttcggcacc cagggcgtga tcgaccgttt cggccagatc
    11761 gaacccaagg tgctgatcgc cgccgccggc taccgctacg ccggcaagaa cctcgatctg
    11821 accgccaagc tcaacgaaat cctcgaacgc ctgccctcgc tgcagcaact ggtggtggtg
    11881 ccctactcca acccgacagc cggggcgggc gacttccgca gcgccgcccg tgtcagcctg
    11941 tggcaggact tctaccaggc cggcggtgaa ccgaagttca ccccggtgtc cttcgagcag
    12001 ccgctgtaca tcctctattc cagcggcacc acgggcgtgc ccaagtgcat cgtccacggt
    12061 gtcggtggca ccctgctgca acacgtcaag gaactgggcc tgcatacgga cctgacggcc
    12121 gacgacacgc tgttctacta caccacctgc ggctggatga tgtggaactg gctggtctca
    12181 gggttagcct tgggcgccag cctggtgctg ttcgacggct cgccgttcca cccaggtgcc
    12241 gagcgcctga tcgacctgat cgacgccgag aacatcagcc tcttcggtac cagcgccaag
    12301 ttcatcgccg ccctggaaaa ggccggcgcc aagccgcgcg agacgcacag gctgcgccgc
    12361 ctgaaggcca tcctctccac cggctcgccg ctggcccacg agagcttcga gtacgtctac
    12421 cgcgatatca aaagcgacgt ctgcctgtcc tccatctccg gcggcaccga catcgtctcc
    12481 tgcttcgccc tcggcaaccc gaccctgccc gtgtggcgcg gcgagctgca gtgcaagggc
    12541 ctgggcatgg atgtgcaggt gtggaacgag gccggccagc cagtcatcgc tgagaaaggc
    12601 gagctggtct gcgcccgcca cttcccgtcg atgccggtcg gcttctggaa ggacgccgat
    12661 ggcgagaaat tccgtagcgc ctacttcgac accttccccg gcgtctgggc ccacggcgac
    12721 tatgccgaga tcaccgaaca cgatggcctg gtgatccacg gccgctccga cgccgtgctc
    12781 aaccccggcg gcgtgcgcat cggcactgcc gagatctacc gccaggtgga gaaggtcgag
    12841 caggtgctgg agtccatcgc catcggccag gactgggaag gcgacgtgcg cgtggtgctg
    12901 ttcgtgcgcc tgcgtgacgg cgtggcgctg agcgacgaac tgcaggcaca gatccgccag
    12961 gtgatccgcg ccaacaccac gccgcgccat gtgccggcca aaatcatcgc cgtcgccgac
    13021 atcccgcgca ccatcagcgg caagatcgtc gagcttgccg tgcgcaacgt ggtgcacggc
    13081 aagccagtga agaacaccga tgccctggcc aacccgcaag cacttgagct gtatcgcgat
    13141 ctgccgcaac tgcagtcatg agccggtaag cgacaccgta agggcaatgg actgccactc
    13201 cagcatctat agtggatgcg cataacccgg acaggatgtt gctgatgcag gtggttttct
    13261 gcctgctggt tgccttgctg tatgtcggcg gcgtggccgc tgacgaacca ctggccttgc
    13321 atatgccgga cgccccgccg ctgaccctgt accacgacga gcgcggccac ggcatggtcg
    13381 gcgacatcac gctcgcggcc atcactctca gcggccgaac ggcacgcatc gtcgacgagc
    13441 cctgggccag agcccaggtg aacgtcgcca gcggccagaa tcaactgatc atcccgctgt
    13501 cgcgtacccc ggagcgtgag caacgctaca cctggatcgt cccgatcatg ccgctggagc
    13561 gcgccttctt cagcctcgac aaacctgtca gcagcttcgc gcaggcacgc cagcgctacc
    13621 ggcgtatctg cgtcgggctc ggcaccgctc aagtggaaat cctgcggcgc gagggtttcg
    13681 ccgacgagca gatcatccag ctcaaactgg gcgaaaaccc ggccatcctg ctcgaacgcg
    13741 ggcgtctcga tgcctggttc accgggattc cggaggcgct gtacatttgg cacaaatctg
    13801 cggaacagcg ccgcaagctt tatcagagcc cggtcctggc cagcaccgac ctgtacctgg
    13861 cctgctccag gatctgcgcc ccgcagatcg tcgagcaact gcgggccgcc gtgctgcaac
    13921 tggaggccag cggcgtcagc ccgcgcctgc gccaggccta tctacccgag ctcgatcgac
    13981 ggtgagcacc cagcccacgc tgccaggcct atagaacaga tcatccacgc cgcaggcctg
    14041 cgccggcttg agcataacgc cagcactggg gcagactgcg actaccccgc acaaccccgg
    14101 tgacaatatg gacgttgtca aaaccctcaa gcccggcaaa cccggcacca agcgcttgca
    14161 agaacgctac ggcgagcaac tcgtcgccgt ccgctaccgc ctcgaccgca aaaccaacac
    14221 ccactacacc acggtcgaac tcatcgtcga acaaaagtac gccctgtaca aaaccccgcc
    14281 acccgctccc acacctccgg tagccctgcg catcttccgc cacgaaaacg acctccagcg
    14341 actgatcaga agcgccggcg gcaagtggga ccgtgagaat caggtgtggc tgatcgagcg
    14401 aagcgaggcc gagaggctgg ggctggcgga acggatcatc tggacataat ggctatatgt
    14461 ggacatcaag atgcctagta atagccacaa acacccagca tcggacacta tgcctacccc
    14521 taggcatgtc gtataaacac tagttataca aatatcatat gaacgacgcg accctaaagc
    14581 tagttaatca aagacagctc gtatcggtaa tgaataaaac gaagtggact gagctgtgca
    14641 attcatttga ctgcgagaat aaagcatctc cgaatgttcg ctataaatta atttacagtg
    14701 aacaagaatt cggtttttca aaaatatggt ggaatcagct tttgcatgag tgcgaagcaa
    14761 tcgaatggat tgatttcaaa ctagtattgc gagaacaccg tggcaatcta ttgccagaca
    14821 aagaaattga tataagcaaa caaattaagg aagcactaca ggcgcatgac atcccttact
    14881 ctgttgaagg agaaaatctt agggtttggg gctatattag cgcagaaaag agtccagtat
    14941 tcgtataaca attggttcaa gtcactcgct tcgctcgctc gggaccggct aaagccggcc
    15001 ccttaaccaa acgttagatg cttatgaaaa agacagttct catactcgtc ccagcattac
    15061 tactctcagg atgtggcgac cctgaatttc actaccaaaa tggtgacgaa tcaaaaaata
    15121 taacgctacg catccctaag aattacataa attatttccc tggcgtgaag tacgaaaaag
    15181 acggacctgt cgtcatcaga ttttcatatc cacaattgga gccactgaca aaagccctac
    15241 cagaagagca aaaagtaact gtcagcatta gtcatttatc cagcctggaa ctcaccaccc
    15301 aagaaaccag aaacccctac tgcgaaacag ataaaaagtg gaaactccta caggcggcgg
    15361 gcattcacgg agagttctat aaattcatcg gaaaatctcc cggcagcgcc agtgcagata
    15421 taacttataa gcccatcaaa aaaacacttg gcctttactg cattacatgc gtggaaaatg
    15481 caaattgtga aattcacgca gtatctagcc aaggaataag ctattccgca ttttatacag
    15541 aagacttaat gccagataag tggcactcta tttacatggc agtcgacaaa atccttagca
    15601 aatttacagc atcgtcgaaa ggcatctaac aattggttca agtcgctcgc ttcgctcact
    15661 cgggaccggc taaagccggc cccttaacca agcgttatgc aagcagtcac ccatgaggaa
    15721 agcacccata tggagccagt atgaaattga gcgacataag agctctaatc attgagtcgc
    15781 caggatggcg aacagtattt gcatttattg tcccactaat cgcagggatt ctgtcgggaa
    15841 tattcgtatc agaaataacg catagctccg aaattgtttg gaaggaattt tataaagcaa
    15901 aaagcttcta cgggctattg gctttgagct tgtgcatgta tttttacaat aaagccattt
    15961 atctacatga aagagaaatt tctcgcttcc tagacgcaga ttactgcacc gcttacatga
    16021 gaagcaaatg cctgccagag gctgcagagc gatacaaaaa gcttatacgc tctggcgacg
    16081 gcggcgaatt gaagcaagca atggatgaac tgaagaaggt gctcaaatga aagtactggc
    16141 cagcccagat tttaatgcaa aagtgccggc actaaacaca gaaaccatta gtagcctttc
    16201 tgcattcata tcaagcgcag agcaatatga aaaaaatgac ttcatattga agaatgtaaa
    16261 ctcaatgtct cttcttgatg gcgatatata tagcgcaaaa atcaactcaa gcagactata
    16321 cttcaccatc ggagctgatg agcaaggcga ctacttgctg ctattagata tagctgcctt
    16381 gcaaaccgca ccatctgtca aaagtagtgc tttcttcaca acaaacaacc caaaaaccaa
    16441 cagctcactc aatccgaagc tcaactctgc aatcaaccca aagctaaact cagcaataaa
    16501 cccaaaatta aattcggcca taaatccgaa gctgaactca gcaataaacc caaagctaaa
    16561 ctcggccatc aacccgaagc tgaattcagc aataaatccg aaactaaact cagcaataaa
    16621 tccaaagcta aactcagcaa taaacccaaa actaaactcc tcactaaacc caaggctcaa
    16681 tcgaagctat ggcggcccgt atttgtacga tgcgaacctt aatcaagaag cgtactcagt
    16741 tagagccaat aacaaaatcg aaatcctgtt caattcgggc ggagattttt atggctttct
    16801 tgtaagcgct aacgaccgag tgaagattga gttcgataca ggaaatacct ggacaggtta
    16861 ttacgttaaa gccaatgaaa aagtttggct tagatattcg cttaacaacg aatggttagg
    16921 gctacttgtc tagcccgcat aacaagtcgc tcaaatcgct cacttcgttc gctgggacgg
    16981 gctaaagccc gccccttagc ttatcgttag gcaaaaaaat agcaggcagg ctcagtaata
    17041 tgaagttcga tagaatagct cgtgaagcgt ttggctcagt gcttggtcca ctggggttca
    17101 gctgtagtga gtcgaaggca tgcaccttct ataaaaaagt cggcactgag ctctatcatt
    17161 ttgtcatgcc agatcaatta agcggccagg aaaagtatga tattaaagtt tttttccact
    17221 cgccgctctt agagccaacc gcatggaatg acaagtttcc ggacaccttg gggattccca
    17281 cagatagctg gagttatctt tctagccgta ctggcgttgg tccacgacaa gagctgtttt
    17341 ggtgtcgaac agaagaagga tttatgcgta actttgaatc aaaggtaaag cccgcactac
    17401 ttcaatttgt agccccatat tttgattcta tacagacatt ggaagaggct attccactaa
    17461 tcaagagcag gcactatgtg gcagtggcgt ctacgctaaa tgctaactaa gcaatgccaa
    17521 ggtcttccac cggcacctcc gtatcggcct tgacagatag cagcaatgag tttccagcaa
    17581 aaaccaatgc gccgcttgca aggctgtttc gggttagcca cagtgcggta ttcattacct
    17641 gcgtccgact cgataccaat tgcctaacaa ctggttcaaa tcgctcgctc cgctcgctgg
    17701 gaccggcgaa gccggcccct taaccaaacg ttaggctaca tatgagaatc agcgcagacc
    17761 agcttgctca agaatcactg actgagttcg gcgtgctggc ggctaagctt ctggcaacgc
    17821 gagagcttag ccagttgtcc gagaagtttg ggtatgcact ggccttcgga agggaaccgg
    17881 cggctgccat agctgaggac cttgctaggt gcttgtgcgg acaaaatgct tcgccggcat
    17941 ctgaataccc caaaatcacc gttaagtatt tcaaggaaaa cgaaagtagt ctgttggcac
    18001 tcgtagagtg ttatgtacaa atgaccgcaa gcgcaaacat tcttttagag ctggttgccg
    18061 cacgaaatgg agaggcaata aatctgtatc tagaaggctt gagtgttgta gcctaacaat
    18121 gcgctcaaag cgctcacttc gttcgctggg accggcgaag ccggcccctt agcttaatcg
    18181 ttaggtgcct caggagggat catgtcttcc acagaaaaca atagtgatga ctggcgagaa
    18241 attcgagcaa gagcggactc tatcgctaat gccattttcc tcatttctgg cggggcactt
    18301 tcactttcaa tctcagtcat cctcagcaac aaaagtgccg ggtacatcac tgcacaagtg
    18361 gcatgtattg cgtccctcgc ttggtactgc ttgctggcgt cactgattct ctttcttgct
    18421 cttaaggggc atatgattct tcaggcatac ctcctacaat ttcgcccaaa ttacgtcaat
    18481 aaacatctta gatttcttaa tggtataagc tgggccattg gattaaccgg gtttatttcc
    18541 ttcattgcag gcatgtttct tatggttcgt accgcaatac ttgccgtcgg cacctaacaa
    18601 tgcgctcaac tgtcgctcac ttcgttcgct ggacagtcaa aagctgcgct tttgcctgcc
    18661 cgttagctta atcgttagcg gtcataagta tgcagattaa tttctatatg gcagatgaag
    18721 atcgaagagc gttccacgaa tacctatatt ctcgtggcgc atacctcgtt ccggagcgtt
    18781 ggccaaccag agatattccc atagtccagg cggcctccga agaggcaagt gagtgcaaag
    18841 acttcaagat tttcaagtct gacctcttcc ctcagtccga atttcagaac agggcttgga
    18901 taacgtggca tgagccaacg aaaaggttct acgttcatgg gcctggaatt cagtatcttg
    18961 tatcgttcac tgatgcaaat ggaatccatc gtggccgcct ctatatgggc cttgtttctc
    19021 cgcgtagctt tgttgagccc cacgggcaat cagttgattg ctacgctgaa aacgagaaaa
    19081 agtacaaggc gttagagaat ttccataaga gttgcgcgcg ctatatacgc aatcactacc
    19141 gcaaagatga gggtggtttc taccatggca aagcaagcga tatggctgtt caaaactacg
    19201 gcgtctcaaa gacgcagctg tgaccgctaa caattcgctg caggcgcgac ggccctgacg
    19261 ggccgcggcc tgagctcaaa cgttataacc tacaaggaag accaaagtat gcgccaccta
    19321 gcaatagccc tcttaataat gttctctact caagttctcg ccgacggcaa gagcgaaaag
    19381 atagagagcc taatgaaggc acttggacta gtagacacat ggacacaaca aattgaacaa
    19441 ggaaaaattt acaacagaaa gatcagctct caaatgctgg atcaaatttt atcccagctg
    19501 aatccaaatg aagagtttca gcaaaaattc aaaaaggctt cagataattt cataacaaaa
    19561 acagaatctc catggtctcc agaaaaaatt gtagaggttt gggctagtta ctatggccca
    19621 gaattcacag aggacgagct tgaccaatta attgcatttt atacttcccc tcttggccaa
    19681 aaagacatcc gtgttactcg cagttcaatg gaaaaattct cgaaatactt ccaagaggcc
    19741 gggcaaccaa tactagaaaa ggccaccgca gagtacattc aggaaatgaa gctcatcgcc
    19801 aaggaatgta actgtaccaa gtagcttata acaattggtt caagtcgttc gcttcgctca
    19861 ctgcgggacc ggctaaagcc ggccccttaa ccaaacgtta ggcactgcta tggccttggt
    19921 cgagtacgaa ctgatcatca atgcgcccca gacggctgtc tatgccgcat ctcaggacta
    19981 ttcagttagg taccagtggg accccttccc tgaaaaaatt gaactcctag gtggtgcaac
    20041 cgaggtagga attggggtta agacacttgt agtcgccaag tctggcttaa caatggaagt
    20101 cgagtttgtt caggttgctc ctcctacaac ggcagccata gtcatgacca aaggcccagc
    20161 attcatcaag agctttggtg gtagctgggt tttcaagccc atcaccgcaa actctacaaa
    20221 ggcaaaattt cgctactcca taaaaaccaa gaaatgggca atacccataa tctcagaata
    20281 cgtagcaagt ctttatttca gaagagcagt taaggccagg cttgccggtc ttaaaaaata
    20341 ctgcgagcaa ggcgcctaac aaatggttca agtcgctcgc ttcgctcatt cgggaccggc
    20401 taacgccggc cccttagctt aatcgttagg ctggccgaag atatgagtta caagagatgg
    20461 atttgtgtcc actgcgatac agccaacacc acagcaacag atatttgttc aaaatgtcac
    20521 agatccagct atgaagagcc ggcaatagct gaaactccaa tagctaattc ttaccaaggc
    20581 atacagctgt taggctcttg gctttttatc ccactaaccc catccattat ggtaattgca
    20641 ataagggatg aagtctggtg gttcgtccca tttgggatcg cagttattgc gctcacaata
    20701 ctaagtgaaa aatctaaatt cttaatttcc aatactactt ggttcaaaaa tatagcttta
    20761 ttttataccc cagcagcggg tgtgcttttc cctcttagcg tttttctcgg aaagaattgg
    20821 gcggccgcat ttatggcaat gcacgtggtt gttcacctac atgctgcatt taacatgcac
    20881 gcacactgcc aaaaccacaa gccaagaaat gaaaattaac gataagtact ctaggcctaa
    20941 caataggttc aagtcgctcg cttcgctcac ttgggaccgg ctaaagccgg ccccttaacc
    21001 aaacgttagg ttccatcatg tgctacatgg ccatagtaag tacaacatcc gaatctgacc
    21061 taacggcact aaatacgccc ctagcgcagt tctcaaggaa cgtaaacgcc ataccagaag
    21121 cggccctcct gcgttaccca aataaatggt tccttggctc aaaagacggt tgcagttgtg
    21181 cattcaggca tcttgatcaa aatgctacag atcttggttt ctcagagccc gtggactggt
    21241 gggaagaaga ccaagaagat atagatgcta cgcttcaagt agtagaagca ttccatacga
    21301 tattgcgcga cggccataaa cttgactgca tagatgcttg ggccaacgat agcaaggaac
    21361 ctaaaaatct tgcaggtgat cttgtggttg acctaaataa agttggcgcc aagagtttcc
    21421 gtttttttga aggctatcgc tttgagctcg aagccagaac ctaactagtg gttcaagccg
    21481 ctcgcttcgc tcactcggga ccggctaaag ccggcccctt aaccaaacgt taggccctat
    21541 atgcagtact caattgctga tactgagagt tttcatcccg tcatggatgc tgagatcaag
    21601 gggcactgcg aattccccgt tgacctaatt tttgtcccgg acattgcaga gtgggctgct
    21661 tccagatgcg gaaatctcat cggcaatcct gtcgcaatgg cagttagaga cggagccact
    21721 aagggggcag gcattctcat taggcaatca atagacgaat cgcaagtcga tagcatccta
    21781 tctcgaatgg agttcggcgg ctttgatcgt gcgcggtcca tactgtcctc acccgagaaa
    21841 tttatgcggc atctagtcct ccatgagctc gcgcacttga ttaacaattg ggggcaagac
    21901 cgagaagacg actgtgatga atgggctttt aagcgtcttg gtgctagggc ctaacaatgc
    21961 gtatatggac tctccccaca agtagtgggc aaagcttttg ctctgctcct ttcgtcggtg
    22021 cggttccatg cgtatatccg gcctttcgcg agctcagtgc tctggccatt ctgtagttcg
    22081 cgcagcgggg gcccagcgct caagcgatct ccaggatcag catcgtcaca ggcctgctgt
    22141 gcagccggcc gaaggaagac cttccctctg ctctccctct cccccatcgc tcctaatggg
    22201 cgcgtcggca gcccaggctg ccccagccta caaggagcaa gaacatgcca aacctgacgt
    22261 tgcatcgcgg tgagaagaac aactggtggc cagcacccga ggtgcggctg atctgcggga
    22321 tgaccctgta tggcccctgg cagccgacgg cggtcagctc gctctggaac acactcaaga
    22381 acgaggtgaa aggcgccctg ggcacctcgc tggagaagaa ggtcgccgcc tacgcccaat
    22441 acctgcgggc gaccggtcgc ccctttgcac tggcgacggc ctggaccgaa gtcggctcct
    22501 tcacgtccga ttacaactac gtgatccgga ttcccaatgc acatttcttc tactggggtg
    22561 gcaccaagga tgccccggac ctcggcgctg ccgccgcgtg gacgacgccc gagcaggtga
    22621 cagccgactt catcgtgctc aacgctccca ccgtggcggc ctcaaccatc ctgggcttcg
    22681 ggcaccacac cggcacgcgg gagatcacct tcttccacga cctgccgatc ggcctgatcg
    22741 agtcctgtaa cggcaggccg atcaccgact atgcgatcaa gagcaagtcc gacctgagct
    22801 tcgacgagag gatcaagtac gccaaatacc tgcgctagcc gcgtaccccg cgtccgagag
    22861 gcttagaagc tagggcggcc ggggtcttcc gggggggtgt cttcctcgat ttcctcaagc
    22921 ttgagttcca tcgcccagtt ggccggtgcc gccgtgggcg cggcaacggg tgcgggcgcc
    22981 ggggcggcag cctgcggggc ggtggggttg tccttgtaca gcttgagctt gaggcgcacg
    23041 ttgttggccg agtcggcgtt cttcactgcc tcctcctcgt cgatgacgcc ttcatgaacg
    23101 aggtcgatca gcgcctggtc gaaggtctgc atgccgaggt tcttcgactt ctccatgatc
    23161 t
//
