LOCUS       NZ_CP102267.1          18804 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP102267.1 Blautia wexlerae DSM 19850 chromosome, complete
            genome.
ACCESSION   NZ_CP102267
VERSION     NZ_CP102267.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:24:05
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1315797
            Orig. end    :: 1334601
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..735
                     /gene_functions="other (smcogs) SMCOG1242:transposase
                     (Score: 144.1; E-value: 9.3e-44)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1147"
                     /transl_table=11
                     /translation="MEVLYKRCCGIDIHKNMMVACIFTSVRKKEIRQFSTMTEDILQLV
                     SWLKETDCEMAAMESTGSYWKPVYNIFEEEQIPIMVVNAQHIKGVPGRKTDVKDAEWIA
                     NLVRHGLVKASYIPNRDQRELREITRYRQEITEERARELNRIQAVLEGCNVKLSSVITD
                     ISGKSGMTILKAIVSGETDPVVLSELAEGRARDKIPEMQKSLQGRISEHQQKMLKHQLG
                     HIESLTALIMDLDADIKKKQNP"
     protocluster    1..18804
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1324505:1325236]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8709..9439
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..18804
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18804
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="5"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     PFAM_domain     25..456
                     /aSDomain="DEDD_Tnp_IS110"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01548.19"
                     /description="Transposase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1147_0080"
                     /evalue="5.80E-31"
                     /label="ctg1_1147"
                     /locus_tag="ctg1_1147"
                     /protein_end="152"
                     /protein_start="8"
                     /score="107.5"
                     /tool="antismash"
                     /translation="CGIDIHKNMMVACIFTSVRKKEIRQFSTMTEDILQLVSWLKETDC
                     EMAAMESTGSYWKPVYNIFEEEQIPIMVVNAQHIKGVPGRKTDVKDAEWIANLVRHGLV
                     KASYIPNRDQRELREITRYRQEITEERARELNRIQAVLEG"
     PFAM_domain     762..1004
                     /aSDomain="Transposase_20"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02371.18"
                     /description="Transposase IS116/IS110/IS902 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1148_0081"
                     /evalue="2.10E-18"
                     /label="ctg1_1148"
                     /locus_tag="ctg1_1148"
                     /protein_end="81"
                     /protein_start="0"
                     /score="66.5"
                     /tool="antismash"
                     /translation="MPGIGRKSAERILAETGVEMEHFQNESRFSSWAGLVPECKESAGK
                     KMSTRIRKGNKYLKATLVECARAGIRNKQSYLYSRY"
     CDS             762..1217
                     /gene_functions="other (smcogs) SMCOG1242:transposase
                     (Score: 107.6; E-value: 1.2e-32)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1148"
                     /transl_table=11
                     /translation="MPGIGRKSAERILAETGVEMEHFQNESRFSSWAGLVPECKESAGK
                     KMSTRIRKGNKYLKATLVECARAGIRNKQSYLYSRYQRIAARRGGKRALIAVAHTMLIA
                     IYHILKEKVPYHDLGADYYSVINQEKIINRNIRTLEKLGVNVMIQPK"
     CDS             complement(1332..2633)
                     /locus_tag="ctg1_1149"
                     /transl_table=11
                     /translation="MEHILLLFFSFLIEAIIMWQYSSSLFLSAHSAKVKISFICFLYGI
                     LFLFSFMEKVWLNIIVYFLINFLFLYIQFKIDLLIAIFHSAILTTIMGLSELFMFSFMS
                     QFAPHFLENTKGGLIIYTLSSKILFLTIIYLLMHFFKKTDPKQENYIDYTDFILMLIPV
                     SCLFIIITFFNIGEHFVFIAPINIMVTLSTVLILFINLLVFGMNQYNHRRNIEFTDMQL
                     LLQKEADSAEYYKMLLSQTENRNILIHDIKKHLQTIKLLNEKKDTSKINAYICQLLDSS
                     DLQEPARICDNEILNAILGRYQRQCSIKSISFHADIRSNILKQFSPYDLTSLFCNLMDN
                     AFEAVEKIPEAFIEVTAQKKENSPFIVIVVINSCRTAPAYDSDHLPISNKENTTKHGYG
                     IKSIKKVTKKHGGNLQMYYDDSSSTFHTIITLKS"
     PFAM_domain     complement(1341..1658)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1149_0082"
                     /evalue="4.40E-21"
                     /label="ctg1_1149"
                     /locus_tag="ctg1_1149"
                     /protein_end="431"
                     /protein_start="325"
                     /score="74.8"
                     /tool="antismash"
                     /translation="SPYDLTSLFCNLMDNAFEAVEKIPEAFIEVTAQKKENSPFIVIVV
                     INSCRTAPAYDSDHLPISNKENTTKHGYGIKSIKKVTKKHGGNLQMYYDDSSSTFHTII
                     TL"
     CDS             complement(2641..3348)
                     /locus_tag="ctg1_1150"
                     /transl_table=11
                     /translation="MRILICDDDTLILEHIYKLLKYYFESAHLKMPEIISYSNGESLLM
                     DKGSKDIVFLDIEMPGMNGIYVGNELKSQNRNVIIFVVTSYSEYLDEAMRFHVFRYLSK
                     PLNKQRFLRNLKDALTYYNTMTQIIPIETHDGIYTVPSSYIIAIEAQGRKIIVHTIQKD
                     YISVHNMNYWAEHLPENSFFQSHRSFIVNFEHITDFDHTTIHMFSNSFTAYLTRRKYTA
                     FKNAYLLYLESTR"
     PFAM_domain     complement(2671..2943)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1150_0084"
                     /evalue="1.70E-16"
                     /label="ctg1_1150"
                     /locus_tag="ctg1_1150"
                     /protein_end="226"
                     /protein_start="135"
                     /score="60.3"
                     /tool="antismash"
                     /translation="GIYTVPSSYIIAIEAQGRKIIVHTIQKDYISVHNMNYWAEHLPEN
                     SFFQSHRSFIVNFEHITDFDHTTIHMFSNSFTAYLTRRKYTAFKNA"
     PFAM_domain     complement(3010..3342)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1150_0083"
                     /evalue="3.10E-16"
                     /label="ctg1_1150"
                     /locus_tag="ctg1_1150"
                     /protein_end="113"
                     /protein_start="2"
                     /score="59.6"
                     /tool="antismash"
                     /translation="ILICDDDTLILEHIYKLLKYYFESAHLKMPEIISYSNGESLLMDK
                     GSKDIVFLDIEMPGMNGIYVGNELKSQNRNVIIFVVTSYSEYLDEAMRFHVFRYLSKPL
                     NKQRFLR"
     CDS             3768..4151
                     /locus_tag="ctg1_1151"
                     /transl_table=11
                     /translation="MMNKKIKRIFCGLTASLCMVGSTVPAMAQTVSFDITVPGDILSQR
                     AKKADYEQRFYVTGNSFNKIGTLHCTSINRKFSSIKSNVASINPNKLSDKAFYLTDAPA
                     EQYYYMTTSASVSNLHVTGRYTP"
     CDS             4232..5326
                     /locus_tag="ctg1_1152"
                     /transl_table=11
                     /translation="MIKKLLLYLILGVITIGSGCGKNVTSEKSNIVNRQENDKAEVEKA
                     FPRTCNIESKSGKVKFNCTLELPESLNGRTIQKTSVEGVHNYNRDKAYSLFAGGKEISE
                     KHQYGDDNNGFDCYRFSDGTSLEVGSTFRWSSATSSFYSYLGVQQSDYIDLFSGGAVSL
                     DKDNCISEVKNDINELGYDAENFSFQAFPLSVDGMRKLRNEELNDGLLEEGQTNEPTSD
                     DEAYFIYAYQENTGIPVFHELMSVAEQLSDDSPDNAPVQAIYSARGLEELSIDYIYDFK
                     NEQNTVTLKPFEEIASVVEEKYENILNDAKYEITRAKLYERVYTDENQKYAEEPVWYFE
                     VNDGSRKTVMLVNAETGKEINLPS"
     CDS             5336..5554
                     /locus_tag="ctg1_1153"
                     /transl_table=11
                     /translation="MSSSTIPYCAVEERRRLNQCMEKTSNDYEKEIYRKIRDMPVPYEK
                     LNEILENSRDIIISLEPLSIKRLSPFE"
     CDS             6067..6231
                     /locus_tag="ctg1_1154"
                     /transl_table=11
                     /translation="MEIDFIQELKKRDELLDGYLRQIEIQEEFIQKQKELIEYLEDHIS
                     KITDIVSSV"
     CDS             6256..7929
                     /locus_tag="ctg1_1155"
                     /transl_table=11
                     /translation="MPDTYDHITLMCRLKAAQRRNKELESGERYIQLEELYQKEYNVYE
                     HKIEKLKKELADAHKETIRVRNYWFQILEDMLREFEKAQKRSAQELRKMEIRALNAEKQ
                     RDDALDKAAVFRHQFYEAASRLEEEQGKNLKLRAQINRDYENSSIPSSKAVRRKKITNN
                     WEKTGRRPGGQPGHKGHCRKRQEPTQPVILLPPPEEVLEDCAFKKTARTIVKQMVSIRM
                     VLNVTEYHADVYYNSHTGERAHAAFPDGVIDDVNYDGSIRAFLFLLNNDCCTSIDKSRV
                     FLSDLTGGKLNISKGMISRLNREFALKTEPERRSAYADMLLSPVMHTDCTNARENGKSC
                     QVYVCATPGGKALYFAREKKGHEGVKGTVTEDYQGILVHDHDITFYNYGADHQECLAHI
                     LRYLKASIENEPDRTWNKKMHALVQEMVHFRNGCRQPHGPDPEIVSGFEKRYREILETA
                     RKEYENIPANDYYKDGYNLFLRMEKYMHNHLLFLHDIRVPATNNEAERLLRNYKRKQAQ
                     AVTFRSFESIDYLCQCMSMLVLMRLEDPANIYDRVSRIFG"
     PFAM_domain     6658..6801
                     /aSDomain="DUF6444"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF20042.1"
                     /description="Family of unknown function (DUF6444)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1155_0085"
                     /evalue="3.80E-06"
                     /label="ctg1_1155"
                     /locus_tag="ctg1_1155"
                     /protein_end="182"
                     /protein_start="134"
                     /score="27.4"
                     /tool="antismash"
                     /translation="KLRAQINRDYENSSIPSSKAVRRKKITNNWEKTGRRPGGQPGHKG
                     HCR"
     PFAM_domain     7036..7824
                     /aSDomain="DDE_Tnp_IS66"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03050.16"
                     /description="Transposase IS66 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1155_0086"
                     /evalue="3.00E-23"
                     /label="ctg1_1155"
                     /locus_tag="ctg1_1155"
                     /protein_end="523"
                     /protein_start="260"
                     /score="82.8"
                     /tool="antismash"
                     /translation="IRAFLFLLNNDCCTSIDKSRVFLSDLTGGKLNISKGMISRLNREF
                     ALKTEPERRSAYADMLLSPVMHTDCTNARENGKSCQVYVCATPGGKALYFAREKKGHEG
                     VKGTVTEDYQGILVHDHDITFYNYGADHQECLAHILRYLKASIENEPDRTWNKKMHALV
                     QEMVHFRNGCRQPHGPDPEIVSGFEKRYREILETARKEYENIPANDYYKDGYNLFLRME
                     KYMHNHLLFLHDIRVPATNNEAERLLRNYKRKQAQAVTFRS"
     CDS             complement(8078..8395)
                     /locus_tag="ctg1_1156"
                     /transl_table=11
                     /translation="MRRKELHIKQAELAETLEISNNHMSSIENGRQKPSLDTFIRLCDC
                     LNVTPDYLLLGSMHAYNLPQDILDKLRLCSQEDIILARDFIELLVKRNRKKHITDSPIS
                     F"
     PFAM_domain     complement(8237..8392)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1156_0087"
                     /evalue="9.60E-13"
                     /label="ctg1_1156"
                     /locus_tag="ctg1_1156"
                     /protein_end="53"
                     /protein_start="1"
                     /score="48.1"
                     /tool="antismash"
                     /translation="RRKELHIKQAELAETLEISNNHMSSIENGRQKPSLDTFIRLCDCL
                     NVTPDYL"
     CDS             8709..8858
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1157"
                     /sec_met_domain="TIGR04223 (E-value: 3.9e-10, bitscore:
                     37.6, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKNVKTTVAKGMKTVLDTVLKTEANTTSCAIMFQPKAPEELMKY
                     RRSK"
     aSDomain        8730..8840
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1157_0010"
                     /evalue="4.10E-10"
                     /identifier="TIGR04223"
                     /label="ctg1_1157"
                     /locus_tag="ctg1_1157"
                     /protein_end="44"
                     /protein_start="7"
                     /score="37.6"
                     /tool="antismash"
                     /translation="TVAKGMKTVLDTVLKTEANTTSCAIMFQPKAPEELMK"
     CDS             8858..9439
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1158"
                     /sec_met_domain="AgrB (E-value: 1.2e-32, bitscore: 110.7,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNICTDKVTDWMIRCKVINESEKELYQYALYSAILQIIPLLLAAG
                     IGFCFGSMRCGIIMILPFMILRKYSGGFHAKRLEFCLLGSSLLLLLCIFLCMRLVYRDA
                     LFFITVVLAISLIQFSPIENNKRKLDLLEKKRYKKIIVISVTVFLITALILLWLNKDRY
                     AICIFIGIQLTASLQIPCLFLKMKKDQKEP"
     PFAM_domain     8873..9397
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1158_0088"
                     /evalue="1.30E-30"
                     /label="ctg1_1158"
                     /locus_tag="ctg1_1158"
                     /protein_end="180"
                     /protein_start="5"
                     /score="106.2"
                     /tool="antismash"
                     /translation="DKVTDWMIRCKVINESEKELYQYALYSAILQIIPLLLAAGIGFCF
                     GSMRCGIIMILPFMILRKYSGGFHAKRLEFCLLGSSLLLLLCIFLCMRLVYRDALFFIT
                     VVLAISLIQFSPIENNKRKLDLLEKKRYKKIIVISVTVFLITALILLWLNKDRYAICIF
                     IGIQLTASLQIP"
     CDS             9582..9965
                     /locus_tag="ctg1_1159"
                     /transl_table=11
                     /translation="MMNKKIKRILCGLTASLCMVGSTVPAMAQTVSFDITVPGDILSQR
                     AVKADSEQRFYVTGSSFNKSGTLRCTSINRNNNTIRSYTASIRPDKLSGNASYQKTAPS
                     GQYYYMTTSASVSNLHVTGRYTP"
     CDS             10064..11158
                     /locus_tag="ctg1_1160"
                     /transl_table=11
                     /translation="MVKKVLLCLILGTVIISSGCEKNATSEENSAETVQNDANSKTENS
                     FPKTYNAESKSGKVKFSCTLEIPENLNGRTIQKTSVAGLRDYNKDKVYAMFAEGKEISK
                     KDQYDWDGGDVANYTFSDGSSLYLDNYVHWGSTTSSLYSYLGVQQADYIDLFSSGSVSL
                     DKDNCISEIKKDMNEFGYDTEDLSFQAFSLSVDAMKKLRDQELNNGLLEEGKTKEPTSD
                     DEAYFIYAYQKNNGIPVFHELMSAAKQMSDDSPDNAPVQAIYSARGLEELNIDYIYDFK
                     NEQDMVTLKPFEEIASVVEEKYENLLNDSKYEITRAKLCERVYTGEDQKYAEEPIWYFE
                     VVENGNNKTVTLVNAETGKEINLP"
     CDS             11171..11458
                     /locus_tag="ctg1_1161"
                     /transl_table=11
                     /translation="MSSSTIPYCAVEERRRLNRCMEKASDDYEKEIYRKIRDMPVPYEK
                     LDEILKDSRDIIISRQHRKNRIRNFLVCVGVFGFMFVVLAMYIIMEKQRG"
     CDS             11463..12224
                     /locus_tag="ctg1_1162"
                     /transl_table=11
                     /translation="MEKTKYLRTDFSRLFKKYPLYLAIVGVAVSFIFSLENYAFEKGMV
                     NVNVMDTYMFAVEMSGKMIAYAFCASAFATVFCEDLENKYLRYSIGRGNLIKYVFSKTI
                     VIYVSSIITMVLGTFLFVIYLRLQLPWTPYLEKPDMSGMYETLWGNGHFMAYIFVVALQ
                     MGMLAGTLSLAASFVSIFITNKMLIMLTPILLYQILMEFRGSGWANIMIFDPALFQFKS
                     DIEYFLIVCGFSLVPSIFFVLGIYRVIKNRL"
     CDS             12236..13096
                     /locus_tag="ctg1_1163"
                     /transl_table=11
                     /translation="MRLLKYIWKNTVLKCFNSKMAVFIILMLVTSRSYLNPLREFSVAV
                     NYPVSWCVFPFVMCSFTYLIIFWFGVIYVNSDVPFMQHVNMYHAIRSGRRQWGLGQIGG
                     IFLRSLIMVLITIFCTILPLLSKIEWSNEWGKLLRTAATTNALSRYQSSVVIYYDIFSE
                     YTPLELILLEILICTLTCTFVGVLMFFLSLYINKIIAVAGGLALAISLFPVLNMHPLIR
                     YKLARFVPTVWAELARIATVDHTYYWLPSLTYMVLFLLVGIAIMTSFIIYKIRHVEFNW
                     ENEDM"
     CDS             13111..13803
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 180.1; E-value:
                     9.3e-55)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1164"
                     /transl_table=11
                     /translation="MDEKKYVIEVSHVNKNFKDNKVLKDVSLRCESGKIYGLVGHNGSG
                     KTVLFKIICGFLVSDEGTVTVNGKIMGKDKDMLTEAGIIIEDPGFLRNWSAYHNLEFLY
                     TIRNKKDKSYLYSILKKVGLNPKLKRPVGKFSLGMRQRLAIAQAIMEDPEILILDEPMN
                     GLDKNGVEEIRELLLKMKKNKLIILASHNREDIDVLCDEVYEMEDGVLRKNSNVKSVTD
                     KSYCLPEV"
     PFAM_domain     13177..13599
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1164_0089"
                     /evalue="1.00E-29"
                     /label="ctg1_1164"
                     /locus_tag="ctg1_1164"
                     /protein_end="163"
                     /protein_start="22"
                     /score="103.9"
                     /tool="antismash"
                     /translation="LKDVSLRCESGKIYGLVGHNGSGKTVLFKIICGFLVSDEGTVTVN
                     GKIMGKDKDMLTEAGIIIEDPGFLRNWSAYHNLEFLYTIRNKKDKSYLYSILKKVGLNP
                     KLKRPVGKFSLGMRQRLAIAQAIMEDPEILILDEPMN"
     CDS             14103..15431
                     /locus_tag="ctg1_1165"
                     /transl_table=11
                     /translation="MQIISSYGVELRKQNIPIRQTLEIYRSAVSYLIGIYVQVWEELAE
                     IPDAKRRFNAAEHLVHTTKKNHACFDFDIRFPKMPSYLRRSAIQHALGTVSSYKTRLDL
                     WEKTDGKSGKPKLVYENHAMPVFYRDVMYREGAEGKDEAYLKLYDGHDWKWSCVRLDHT
                     DMEYLRKCWSGKKASAPTLEKRHQKYFLRFSYKEEVTLTKTPVKEQIICSVDLGINTDA
                     VSTIMRADGTVLGRRFIDHPSEKDRMYRTLGRIRRFQREHGSAQTQGRWAYTKRLNTEL
                     GKKTAGAIVRYAEENHADVIVFEYLEMQGKISGKKKQKMHLWRKRDIQKCCEHQAHRKG
                     MRVSRICAWNTSRLAYDGSGAVTRDWENHSLCTFQTGKRYNCDLSASYNIGARYFIREL
                     LKPLPATERSLLEAKVPPVKRRTSCVYADLRKLHSEMELLKAA"
     aSDomain        14937..15158
                     /aSDomain="TIGR01766"
                     /aSTool="tigrfam"
                     /description="tspaseT_teng_C: transposase, IS605 OrfB
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1165_0011"
                     /evalue="1.10E-08"
                     /identifier="TIGR01766"
                     /label="ctg1_1165"
                     /locus_tag="ctg1_1165"
                     /protein_end="352"
                     /protein_start="278"
                     /score="33.4"
                     /tool="antismash"
                     /translation="TELGKKTAGAIVRYAEENHADVIVFEYLEMQGKISGKKKQKMHLW
                     RKRDIQKCCEHQAHRKGMRVSRICAWNTS"
     CDS             15752..16516
                     /locus_tag="ctg1_1166"
                     /transl_table=11
                     /translation="MQTSKDFLHIFLDMGDALLNSGAEIFRVEDTLNRMGYACGAAQMN
                     VFVITSSIVITMEFPEEGARTQTRRIRESGGNDFTKLEQLNDLSRRFCNHPVPAAELRK
                     EFDKININRTKPLWKLLGSLLAACSFAFFYGGSIPDAVAAGFGAVLIWGLQQYLRPVCM
                     NEVTFQFVASFFTGCAICGLTLLCPFLRMDKIMIGDIMLLIPGLMSTNAIRDVLIGDTL
                     SGIIRLIAALLLAAALALGFMGAIILFGRFGL"
     PFAM_domain     15779..16492
                     /aSDomain="ThrE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06738.14"
                     /description="Putative threonine/serine exporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1166_0090"
                     /evalue="2.30E-61"
                     /label="ctg1_1166"
                     /locus_tag="ctg1_1166"
                     /protein_end="247"
                     /protein_start="9"
                     /score="207.4"
                     /tool="antismash"
                     /translation="IFLDMGDALLNSGAEIFRVEDTLNRMGYACGAAQMNVFVITSSIV
                     ITMEFPEEGARTQTRRIRESGGNDFTKLEQLNDLSRRFCNHPVPAAELRKEFDKININR
                     TKPLWKLLGSLLAACSFAFFYGGSIPDAVAAGFGAVLIWGLQQYLRPVCMNEVTFQFVA
                     SFFTGCAICGLTLLCPFLRMDKIMIGDIMLLIPGLMSTNAIRDVLIGDTLSGIIRLIAA
                     LLLAAALALGFMGAII"
     CDS             16513..16959
                     /locus_tag="ctg1_1167"
                     /transl_table=11
                     /translation="LTAAIMIQLITGAIGSVGFGILFHIKKKYLPLVAVGGFLSWLVFL
                     LGKEFWGNVFLPTLMAGFVTDVYAEILARICKETSTSFFVTSVIPLIPGSTLYYCMNSI
                     VEGNTVRALEYGRDTFLFAFGIAAGMSIAWSICYFLRTVRKKQN"
     PFAM_domain     16534..16917
                     /aSDomain="ThrE_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12821.9"
                     /description="Threonine/Serine exporter, ThrE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1167_0091"
                     /evalue="2.00E-28"
                     /label="ctg1_1167"
                     /locus_tag="ctg1_1167"
                     /protein_end="135"
                     /protein_start="7"
                     /score="99.2"
                     /tool="antismash"
                     /translation="QLITGAIGSVGFGILFHIKKKYLPLVAVGGFLSWLVFLLGKEFWG
                     NVFLPTLMAGFVTDVYAEILARICKETSTSFFVTSVIPLIPGSTLYYCMNSIVEGNTVR
                     ALEYGRDTFLFAFGIAAGMSIAWS"
     CDS             17222..17815
                     /locus_tag="ctg1_1168"
                     /transl_table=11
                     /translation="MTKTKSMIYCGLFTALIAAGAFIKIPVPVVPFTLQYLFTMLAGLF
                     LGSRRGMISVVAYMLLGLAGLPIFSEGGGIWYIFKPSFGYIIGFCLGTYVTGLIAERLK
                     QKTVFRYLLANLAGLMIVYICGMVYYYVICNYVIDTPIGIWPLILYCFLLAVPGDIALS
                     ILGAVIAKRVRPVVHQYLFDSKSNVRLKTEELAK"
     PFAM_domain     17306..17743
                     /aSDomain="BioY"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02632.16"
                     /description="BioY family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1168_0092"
                     /evalue="8.00E-37"
                     /label="ctg1_1168"
                     /locus_tag="ctg1_1168"
                     /protein_end="174"
                     /protein_start="28"
                     /score="126.4"
                     /tool="antismash"
                     /translation="VVPFTLQYLFTMLAGLFLGSRRGMISVVAYMLLGLAGLPIFSEGG
                     GIWYIFKPSFGYIIGFCLGTYVTGLIAERLKQKTVFRYLLANLAGLMIVYICGMVYYYV
                     ICNYVIDTPIGIWPLILYCFLLAVPGDIALSILGAVIAKRVR"
     CDS             17812..18804
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF06968"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1169"
                     /sec_met_domain="PF06968 (E-value: 7e-14, bitscore: 49.7,
                     seeds: 824, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.2e-14, bitscore: 52.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPLILAQEIIDGRRITREDDLSYFLTCDLDELCEGADRIREAYI
                     GDKVDLCSIINGRSGRCPEDCKYCAQSVHHHTSCEIYDFLPEEKILEACKMNEEEGVDR
                     FSIVTAGKALTGKEFDQAIHAYETMHKECNIDLCASMGFLSSEQLHRLHEAGVTSYHHN
                     IETSKRNFPNICTTHTYDMKIETLKKVKAEGMCACSGGIIGMGETWEDRLDMAVSLAEL
                     GIDSIPINALMPIPGTPLEHLDQLSEQDILRTIAFFRYINPEANIRLAAGRALLTNDGE
                     TAFKSGASATITGNMLTTVACATIRSDRKMLSDMGRNVTPEYWKEVEES"
     aSDomain        17890..18759
                     /aSDomain="TIGR00433"
                     /aSTool="tigrfam"
                     /description="bioB: biotin synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1169_0012"
                     /evalue="2.70E-118"
                     /identifier="TIGR00433"
                     /label="ctg1_1169"
                     /locus_tag="ctg1_1169"
                     /protein_end="316"
                     /protein_start="26"
                     /score="392.5"
                     /tool="antismash"
                     /translation="TCDLDELCEGADRIREAYIGDKVDLCSIINGRSGRCPEDCKYCAQ
                     SVHHHTSCEIYDFLPEEKILEACKMNEEEGVDRFSIVTAGKALTGKEFDQAIHAYETMH
                     KECNIDLCASMGFLSSEQLHRLHEAGVTSYHHNIETSKRNFPNICTTHTYDMKIETLKK
                     VKAEGMCACSGGIIGMGETWEDRLDMAVSLAELGIDSIPINALMPIPGTPLEHLDQLSE
                     QDILRTIAFFRYINPEANIRLAAGRALLTNDGETAFKSGASATITGNMLTTVACATIRS
                     DRKMLSDMG"
     PFAM_domain     17989..18456
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1169_0093"
                     /evalue="6.30E-14"
                     /label="ctg1_1169"
                     /locus_tag="ctg1_1169"
                     /protein_end="215"
                     /protein_start="59"
                     /score="52.8"
                     /tool="antismash"
                     /translation="GRCPEDCKYCAQSVHHHTSCEIYDFLPEEKILEACKMNEEEGVDR
                     FSIVTAGKALTGKEFDQAIHAYETMHKECNIDLCASMGFLSSEQLHRLHEAGVTSYHHN
                     IETSKRNFPNICTTHTYDMKIETLKKVKAEGMCACSGGIIGMGETWEDRLDM"
     PFAM_domain     18493..18759
                     /aSDomain="BATS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06968.15"
                     /description="Biotin and Thiamin Synthesis associated
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1169_0094"
                     /evalue="5.00E-13"
                     /label="ctg1_1169"
                     /locus_tag="ctg1_1169"
                     /protein_end="316"
                     /protein_start="227"
                     /score="49.1"
                     /tool="antismash"
                     /translation="PINALMPIPGTPLEHLDQLSEQDILRTIAFFRYINPEANIRLAAG
                     RALLTNDGETAFKSGASATITGNMLTTVACATIRSDRKMLSDMG"
ORIGIN
        1 atggaagtat tgtataagcg gtgttgtggg attgacattc ataaaaatat gatggtagcc
       61 tgtattttta cgagtgtcag aaaaaaagaa atccgtcagt tttcaacaat gacggaagat
      121 attctccaat tagtttcgtg gctgaaagaa acagattgtg agatggctgc catggaaagt
      181 acgggctctt attggaaacc tgtatataat atatttgaag aagaacagat accgatcatg
      241 gttgtgaatg cgcagcatat caaaggagtt cccggacgta agacggatgt aaaagatgca
      301 gagtggattg ccaatctggt acgccatgga ttagtaaaag caagttacat accaaatagg
      361 gatcaaagag aactgcgaga aataacccgt taccgccagg agataactga agaacgtgct
      421 cgtgaattaa atcgaatcca ggctgtgtta gaaggctgca atgttaaatt gagcagtgta
      481 attaccgata tcagcggaaa aagcggtatg acaattttaa aggcaattgt atctggagaa
      541 acagatccgg ttgttttaag tgaacttgcc gaaggaagag ccagagataa aattccagaa
      601 atgcagaaat ccctacaagg acggatatca gaacatcagc aaaaaatgtt gaaacatcaa
      661 cttgggcata ttgaaagcct gaccgcttta attatggatt tagatgcaga tattaaaaaa
      721 aaacagaatc cataaattgg gcaatcgaag ctttggatga tatgcctggg attggaagaa
      781 aaagtgcaga acgaatttta gcggaaactg gtgtggaaat ggagcacttt caaaatgaat
      841 cccgtttcag ctcatgggcg gggcttgtgc ctgagtgtaa ggaaagcgcc ggaaaaaaga
      901 tgagtacacg aatacggaaa ggaaataaat atttgaaagc aacgctggtg gaatgtgctc
      961 gtgctggaat acgaaacaag caaagttatc tctactcccg ttatcaaaga attgccgcgc
     1021 gcagaggtgg gaaaagggct ttaattgcag tagcccatac catgttaatc gcgatttatc
     1081 atatactaaa agagaaagtt ccttatcatg accttggagc ggactactac tccgttatca
     1141 atcaagaaaa gataatcaat aggaatattc gtacattaga aaagttaggg gtaaatgtaa
     1201 tgattcagcc gaaatgaatc tctttaactg tataattaag agaaggaaat aagcccgcca
     1261 aaaggcgagc ttatttagaa tgcttgttta taggttatcg ctgaactacg ttttcaagac
     1321 agccccattt tttatgattt taaagtgata atggtgtgga acgtggaact ggagtcatca
     1381 taatacattt gaagattacc tccatgtttt tttgtgactt tttttatact ttttatacca
     1441 taaccgtgtt ttgtggtatt ttctttattg gatattggaa gatgatcaga atcatatgcc
     1501 ggagcagttc ggcatgaatt aataacaaca ataacaataa aaggagagtt ctcttttttc
     1561 tgtgctgtta cttcgataaa agcttctggt attttttcta ctgcttcaaa agcgttatcc
     1621 atgagattac aaaataaaga agttagatca taaggagaaa attgttttaa aatattactt
     1681 cggatatctg catggaagct gatgcttttt atgctgcatt gtcgttggta acggccaagg
     1741 atagcgttta aaatttcatt atcgcaaatt ctggctggct cctgcagatc agatgaatca
     1801 agaagctgac agatgtaagc atttattttt gaagtgtcct ttttttcatt caataatttg
     1861 atagtttgca ggtgcttttt gatgtcatga atcaggatat tccgattttc cgtctgagaa
     1921 agaagcattt tataatattc tgcagaatca gcttcttttt gaagcaaaag ctgcatatca
     1981 gtgaattcta tgtttcgacg atgattatat tgattcattc caaataccag aagattaata
     2041 aaaagaataa gcactgtact cagcgttacc ataatattta ttggtgctat aaacacaaaa
     2101 tgttccccaa tattaaaaaa agttattatt ataaacagac aggaaacagg aatcaacatc
     2161 aaaataaaat ctgtataatc aatatagttt tcctgtttag gatctgtttt tttgaaaaaa
     2221 tgcataagca gataaataat tgtaaggaat aaaatcttgc tggacaatgt atatataatt
     2281 aaaccgccct tcgtattttc aagaaaatgt ggggcgaact gagacataaa gctaaacata
     2341 aaaagctcag aaagtcccat tatggttgtt aaaatagcgg aatgaaatat tgcaattaac
     2401 agatcaattt taaactgtat atataaaaac agaaagttta tcagaaagta tacaataatg
     2461 ttaagccaga ctttttccat gaaagagaaa aggaataaaa tgccataaag aaagcatata
     2521 aatgatattt ttactttagc ggaatgagca gataaaaaca ggctggaaga atactgccac
     2581 ataatgattg cttcgattag aaaactaaaa aataatagta agatatgttc cataaaatct
     2641 ttacctcgta ctttcaagat atagaagata agcattttta aatgctgtat attttcggcg
     2701 tgtaaggtat gcagtaaatg aattgctgaa catatgtata gtagtgtgat caaaatctgt
     2761 aatatgttcg aaattaacaa taaaacttcg gtgtgactga aaaaaactgt tttcaggtag
     2821 atgctctgcc cagtagttca tattgtgaac agaaatataa tctttttgga ttgtgtgtac
     2881 aattattttt cgcccttggg cctcaatggc aataatatag gaagagggaa cagtataaat
     2941 tccatcatgt gtttctatgg gaattatttg tgtcatcgta ttgtaatagg ttaatgcatc
     3001 tttcaaattt ctgagaaatc gttgcttatt caatggcttt gaaagataac ggaatacatg
     3061 aaaacgcatg gcttcatcca gatactcaga atatgaggta acaacaaaaa tgattacatt
     3121 tctgttttgg gattttaact cgtttccaac ataaattcca ttcataccag gcatttctat
     3181 atcaagaaaa actatatctt tagaaccttt gtccattaaa agactttccc catttgagta
     3241 ggatataatt tcaggcatct taagatgagc agattcaaaa taatatttta ataatttata
     3301 tatatgttcc agaattaatg tgtcatcatc acaaataaga atccgcattc tatatcacca
     3361 gactttcttt taaatatatt catcatatca tatacatata gaacttgcaa aggatgtaca
     3421 tgaaaagaca aaatgatagc atttttggtt gtatattcag aactaagata gcttcttgaa
     3481 aaaacaataa gggaaaaaaa agaacagtgg gaatattcga ctgttctttt ttgtatgcct
     3541 gtcaaaatga tataagtgaa tttgtaatat gccacagatc cctggtctgt ttctaaaaat
     3601 gagaaaagac caaaaagaga cttaaaatgt cgattcatgc aaaatgggtt gaaaattaca
     3661 aaaaagtata gataataaca cttgtcattg attttactgc aaattacgcg cgtaaagaaa
     3721 cattacaaat gtcctaagga tttgtgaaag aaaagaggaa acagattatg atgaataaaa
     3781 aaatcaaaag aatcttttgc ggattaactg catctttatg catggttgga agtactgtac
     3841 cagccatggc acagactgtg agctttgata ttaccgtacc gggagatatc ttatcccaga
     3901 gagctaaaaa ggctgattat gaacagagat tttatgtaac aggaaattca tttaacaaaa
     3961 taggaacctt gcactgtaca tcaattaata ggaaatttag ttcgataaaa tcaaatgttg
     4021 cttctattaa tccaaataaa ttatcagata aggcttttta tcttacagat gctccggcag
     4081 agcagtatta ttatatgaca acatctgcaa gtgtttcaaa tctgcatgta acaggacgat
     4141 atactccgtg atgttatttt ttctataatg gatacccaga gaagatactg attattgtat
     4201 cttctctggg tagtggtaag ggagaaaaat tatgattaaa aaactattat tatatttaat
     4261 attaggggta ataactatag gttcgggatg tgggaaaaat gtaacttcag aaaaaagcaa
     4321 tattgtaaat agacaggaaa atgataaagc tgaagttgag aaagcttttc cgaggacgtg
     4381 taatatagaa tcaaaatccg ggaaagtcaa atttaattgt acattggaat taccagaaag
     4441 tctgaatgga agaactatac agaaaacttc tgtagaaggt gtacataatt ataataggga
     4501 caaggcatat tctttgtttg caggaggaaa agagatatct gagaaacacc aatatggtga
     4561 tgacaataat ggttttgatt gttatagatt ttctgatgga acaagccttg aagtaggttc
     4621 aacttttcgt tggtccagtg ctacttcttc tttttattca tatcttggag tgcaacagtc
     4681 agattatata gacttgtttt cgggtggagc agtttccctt gacaaagaca actgtatttc
     4741 agaagtaaaa aatgacataa atgaacttgg atatgatgca gagaattttt cttttcaggc
     4801 gtttccctta agtgttgacg gaatgagaaa attaagaaat gaggaattaa atgatggttt
     4861 gctggaagaa ggacaaacga atgaacccac atcagacgat gaagcgtact ttatctatgc
     4921 ctatcaggaa aataccggaa ttcctgtatt tcatgaatta atgagcgttg cagagcaatt
     4981 atcggatgat tctccagata atgcacctgt acaggccatt tattctgccc gtggtctgga
     5041 agaattaagt atagattata tttatgactt taaaaatgaa cagaatacgg taacactgaa
     5101 accttttgaa gaaattgcgt cagtagtaga agagaaatat gaaaacatat tgaatgatgc
     5161 aaaatatgaa attacacggg ctaaattata tgaacgtgtt tatacagatg agaatcagaa
     5221 atatgcagaa gaaccagtct ggtattttga ggtaaatgat ggcagtagaa aaacagtaat
     5281 gttagtcaat gcggaaaccg gtaaagaaat taatttacca tcataggaga ttgatatgag
     5341 cagttctaca attccatatt gtgcagtaga agaaagaaga agattaaacc agtgtatgga
     5401 aaaaacatcg aatgattatg aaaaggaaat atacagaaaa attcgcgata tgccggttcc
     5461 gtatgaaaaa ctaaatgaaa tattagagaa tagcagagat attatcatat ctttagaacc
     5521 cttgtccatt aaaagacttt ccccatttga gtaggatata atttcaggca tcttaagatg
     5581 agcagattca aaataatgtt ttaataattt atatatatgt tccagaatta atgtgtcatc
     5641 atcacaaata agaatccgca ttctatatca tcagacgttc ttttaaatat attcatcata
     5701 tcatatacat atagaacctg caaaggatgt acatgaaaag ataaaataga tgaatttttg
     5761 gttgttactg ttcaaaggta tgtataagtc attgtaaaaa gtgacgaaat tattttctct
     5821 attttgtgga taattatctt cagcagaaaa aactgtattt atagtttttt ctgctgaaga
     5881 taattatcca caaaagttat acaccgaatc ctatccattc tttcagacag aggccttata
     5941 tctactcatt tccaatctta taatggagat ttatccacag tcagattgcc caatgggtca
     6001 tttccggaaa ttcgcttttt tcctgcattt ctgctatact tttttcaaga aagagaggtt
     6061 gtttttatgg agattgattt tatacaggaa ctaaaaaaac gtgatgaact tcttgacggc
     6121 tatctcaggc agatcgagat ccaggaggaa ttcatccaga aacagaaaga gctgatcgaa
     6181 tatctcgagg atcatatctc aaagatcaca gatatcgtca gcagtgttta gcaggactgt
     6241 accggaggaa aacgtatgcc tgatacttat gatcatatca ctctcatgtg tcggctgaaa
     6301 gctgcacaac gcagaaacaa agaactggaa tctggtgaaa gatatatcca gttagaagaa
     6361 ctttatcaga aagagtacaa cgtttatgaa cataagattg agaagctgaa aaaagaactt
     6421 gcagatgcgc acaaagaaac gatccgtgtg cgcaattact ggtttcagat actggaggat
     6481 atgctccggg agtttgaaaa ggcacaaaaa aggtccgcgc aggaactccg aaaaatggag
     6541 atccgtgcac tgaatgcaga aaagcaaaga gatgatgcac tggataaagc agccgttttc
     6601 agacatcagt tttatgaagc ggcatccaga ctggaagaag aacagggaaa gaatctgaaa
     6661 ctacgggcac agatcaaccg cgattatgaa aactcttcta ttccttcttc aaaagcagta
     6721 cgacgcaaaa agatcacaaa caactgggaa aaaacaggca gaagaccagg cgggcagccc
     6781 ggccacaaag ggcactgccg gaaaagacag gagcctacac agccagttat tcttcttccg
     6841 ccacctgaag aagtgctcga agactgtgct tttaaaaaga ctgccaggac catcgtaaag
     6901 cagatggtaa gtatccgtat ggtcctgaat gtaacggaat atcatgcaga tgtttattat
     6961 aacagtcata cgggagaacg tgcacatgca gcatttccag acggagttat cgatgatgtg
     7021 aattatgatg gcagcatacg ggcatttctg ttccttctga acaatgactg ctgtacatcc
     7081 attgataaga gcagggtatt tctgtccgac ctgacgggtg gaaaactgaa tatttccaaa
     7141 ggcatgataa gcagactaaa ccgggagttt gctttaaaaa ctgagcctga acgcaggtct
     7201 gcctatgcag atatgctgct ttcccctgtt atgcatacgg attgtacaaa tgccagggaa
     7261 aacggaaaga gctgccaggt atatgtctgt gcaacaccgg gcggaaaagc cctgtacttt
     7321 gcccgcgaga aaaagggaca cgaaggagta aagggtacgg ttacagaaga ctatcagggg
     7381 atccttgtcc atgaccatga tattaccttt tataattatg gagcagatca tcaggaatgc
     7441 cttgcccata tactgcggta tctgaaagcc agcatagaga acgaaccaga ccgtacctgg
     7501 aataaaaaaa tgcatgcact ggtgcaggaa atggtccact tccgaaatgg atgccggcag
     7561 ccacacggac cagatccgga aatagtctcc ggattcgaaa aacgataccg tgagatactg
     7621 gaaactgccc ggaaagaata tgaaaacatt ccggcaaatg attattataa agacgggtac
     7681 aatttattcc tgagaatgga gaaatacatg cacaaccatc tgttgttcct gcatgatatc
     7741 cgggtacctg ccacgaataa tgaagccgaa aggcttctaa ggaattataa gcggaaacag
     7801 gcgcaggccg tgacattcag aagtttcgaa agcatcgatt atctctgcca atgcatgagc
     7861 atgcttgttt tgatgcgcct tgaagatccg gcaaatatat atgacagagt gtctagaata
     7921 tttggataaa gaaaaccgat ggctttgact gttatcagtc tacaccatcg gttttctcaa
     7981 gtccagctaa cccttgaaca gtaacttttg gttacttatt tagaaataac aaaaaagaac
     8041 agtgaaaata ttctactgtt cttaatatgt atgtttgtta aaaggatata ggtgagtctg
     8101 taatatgctt ttttctgttt ctttttacaa ggagttctat aaagtctctg gcaagaatga
     8161 tatcctcttg gctgcacagg cgtagcttat caagaatatc ctgtggtaaa ttatatgcgt
     8221 gcatactacc taaaagaaga tagtcgggag taacatttaa acagtcacat aaccggatga
     8281 aagtatcaag acttggtttc tgacgtccat tttcgatgga tgacatatga ttatttgaga
     8341 tttcaagtgt ttcggctagc tccgcctgct ttatatgtaa ttctttccgc cgcatcttaa
     8401 tacggctccc catgtcatca taatgaaatt cgatttataa caccctcttt catatgatga
     8461 atcttaacaa tatactttta caaaatgaag aatgttatac agaaaaattc tgttgtacat
     8521 ttgattttct gtatttcata gagaaaaatt ctgctataca tagtatttta aactggaaaa
     8581 gccaataatt atccattttt gaagaaaaat aatctcttca ttccaaacct atcgaattat
     8641 aagacaaaga gagttatgat ataacctgca agaaatcaat gacaatttcg tgaaaggaga
     8701 acgagattat gcagaaaaat gtaaaaacta cagtggccaa aggtatgaaa acagtattgg
     8761 atactgtgtt aaagacagaa gctaatacaa catcctgtgc tatcatgttt cagccaaaag
     8821 cacctgaaga actgatgaaa tacaggagaa gtaagtaatg aatatatgca cagataaagt
     8881 aacggactgg atgatacgat gcaaagttat taatgaaagt gagaaggaat tatatcagta
     8941 tgcattgtat agtgctattt tacagataat tccattattg cttgcagctg gaattggttt
     9001 ttgctttggg agtatgagat gtgggattat aatgattttg ccatttatga tattgagaaa
     9061 atatagcggt ggatttcatg ccaaacgatt agagttttgc ctgttggggt caagtctgtt
     9121 actgcttttg tgcatatttc tctgtatgag gttagtttac agggatgcgt tatttttcat
     9181 tacggttgtg ttagctataa gcctgattca attcagtcca atagaaaata acaagcgtaa
     9241 gttggatttg cttgaaaaaa aacgttataa aaaaataata gtgataagtg ttacagtatt
     9301 tttgattaca gcactaattt tgctttggtt aaataaggat agatatgcaa tatgtatttt
     9361 tattggaata cagttaacag ctagtttaca aattccctgt ctgtttctga aaatgaaaaa
     9421 agaccaaaaa gagccttaaa atgtcgcttc atgcaaaatg ggttgaaaat tataaaaaag
     9481 tatagataat aacacttgtc attgatttta ctgcaaatta cgcgcgtaaa gaaacattgt
     9541 aaatgctcta atgatttgcg aaagaaaaga ggaaacagat tatgatgaat aaaaaaatca
     9601 aaagaatcct ttgcggatta acggcatctt tatgtatggt tggaagtact gtaccagcca
     9661 tggcacagac tgtgagcttt gatattaccg taccgggaga tattttatct cagagagctg
     9721 ttaaagctga ttccgaacag agattttatg tgacagggag ttcatttaac aaaagtggaa
     9781 cattgcgttg tacatcaatt aaccgaaaca acaatacaat aagatcatac actgcaagta
     9841 ttagaccaga taaattatct ggaaatgcat cctaccagaa aacggcaccg tcaggtcagt
     9901 attactatat gacaacatct gcaagcgttt ctaatctgca tgtaacagga cgctatactc
     9961 cgtgatattg cattgtttgt gacgaaataa tgacgaataa ttaataacac agggatagga
    10021 tgcaagttat cctatccctg tgtgtggata aaggagatca gctatggtaa aaaaagtgct
    10081 gttatgttta attctgggga cggttattat aagttcagga tgcgaaaaaa atgcaacttc
    10141 agaagaaaac agtgcggaaa ctgtacagaa tgatgcaaat tcaaaaacag aaaattcttt
    10201 tcccaaaaca tataacgcag aatcgaaatc tggaaaagta aaattcagtt gtacattgga
    10261 aataccagaa aatttgaatg gaagaactat acagaaaact tcagtagcag gcttacgaga
    10321 ttataataaa gataaggtat atgctatgtt tgctgaagga aaagaaatat ctaaaaaaga
    10381 tcaatacgat tgggatggtg gtgatgttgc caattataca ttttctgacg gctcaagtct
    10441 ttatttagat aactatgttc attggggaag tactacgtct tctctttact catatcttgg
    10501 agttcagcag gcagattata tagacctgtt ttcgagtgga tcagtttctc ttgataagga
    10561 caactgcatt tcagagataa aaaaggatat gaatgaattt gggtatgata cagaagatct
    10621 ttcttttcag gcattttcat tgagcgttga tgcgatgaaa aaactaagag atcaggaatt
    10681 aaataatggt ttgctggaag aaggaaaaac aaaggagcca acatcggatg atgaggcgta
    10741 cttcatctat gcttatcaga aaaataatgg tattcctgta tttcatgaat taatgagtgc
    10801 tgcaaagcag atgtcagatg attctccgga taatgcacct gtgcaggcta tttattctgc
    10861 ccgtggtctg gaagaattaa atatagatta catctatgac tttaaaaatg aacaggatat
    10921 ggtaacactg aaaccttttg aagaaattgc gtcagtggta gaagagaaat atgaaaactt
    10981 attaaatgat tctaaatacg agatcacacg tgcaaaatta tgtgaacgtg tttatacagg
    11041 tgaagatcag aaatatgcag aagaaccaat ctggtatttt gaggtggttg agaatggtaa
    11101 taataaaaca gtaacgctgg ttaatgcaga aacaggcaaa gaaattaacc tgccgtaaag
    11161 gagatcagat atgagcagtt ctacaattcc atattgtgca gtagaagaaa gaaggagatt
    11221 aaaccgatgt atggaaaaag catcggatga ttatgaaaaa gaaatctata gaaaaattcg
    11281 tgatatgcct gttccgtatg aaaaattaga tgaaatttta aaggatagca gagatattat
    11341 catatccaga caacatagaa aaaatagaat tagaaatttt cttgtttgtg ttggcgtatt
    11401 tggctttatg tttgtagtgc tagccatgta tattattatg gaaaagcaaa ggggatgatt
    11461 gaatggaaaa gacaaaatat cttagaacgg attttagccg tttatttaag aaatatccgc
    11521 tgtatcttgc aatcgttggt gtggcagtct cttttatttt ttctcttgaa aattatgctt
    11581 ttgaaaaagg tatggtaaac gtcaatgtta tggatactta tatgtttgca gttgaaatgt
    11641 ctgggaaaat gattgcgtat gcattttgtg cttcagcttt cgcaactgta ttttgtgaag
    11701 accttgaaaa caaatatttg cggtatagta ttggacgagg taatttaata aaatatgtat
    11761 tttcaaaaac gatagtaatt tatgtatctt ccataataac aatggtttta gggacatttt
    11821 tatttgttat atatttgcgg ctgcagcttc cctggacacc ttatttagaa aaaccagata
    11881 tgtcaggaat gtatgagacc ctatggggaa acgggcattt tatggcatat atttttgtag
    11941 ttgctttaca gatgggaatg ttggctggca cattgtctct ggcagcttca tttgtttcta
    12001 tatttatcac taataaaatg ttgattatgt taactcccat cttactatat caaattttaa
    12061 tggaattccg tggaagtgga tgggcaaata taatgatatt tgatcctgcg ttatttcagt
    12121 ttaaatcgga tatagaatat tttttgattg tatgtggttt cagtttagta ccatcaattt
    12181 tctttgtttt gggaatatac agagtaataa aaaatagatt gtagaggtga caaacatgcg
    12241 gttattaaaa tatatatgga aaaatacagt attaaaatgt tttaatagta aaatggcggt
    12301 ttttataatt ttaatgcttg tcacaagccg ttcctattta aatcctttac gggaattctc
    12361 tgttgcagta aattatcctg tatcctggtg cgtttttccg tttgtaatgt gtagttttac
    12421 atatttgatt atattctggt ttggtgtaat ttatgtgaat tctgatgtac cttttatgca
    12481 gcatgtgaat atgtatcatg caattcgaag tggtaggcga caatggggat taggtcagat
    12541 tgggggtata tttttacgtt cgttgataat ggtattaata actattttct gcacaatact
    12601 tccattgctg tccaaaatag aatggagcaa tgaatgggga aagctgttaa ggactgcggc
    12661 aactacaaat gctctttcac gatatcagag cagtgtggtt atttactatg atattttttc
    12721 agaatataca ccacttgagc ttatactgct tgaaatttta atttgtacac tgacttgtac
    12781 atttgttggt gttctgatgt tttttcttag tttatatata aataagatca ttgcagttgc
    12841 cggagggctt gcactggcaa tctccttgtt tcctgtattg aatatgcatc cgttaatccg
    12901 ctataaactt gcacgttttg ttcctactgt atgggctgag ttagcaagaa ttgcaacagt
    12961 ggatcatact tattactggt taccgtcttt gacatacatg gtgttgtttt tgttagtggg
    13021 aatagcaata atgacaagct ttattatata taagatcaga catgtggagt ttaactggga
    13081 aaatgaagat atgtaggagg aacaggtatt atggatgaaa agaaatatgt catagaagta
    13141 tcgcatgtaa ataaaaattt caaggataat aaagtattaa aagatgtttc tctcagatgt
    13201 gaaagtggaa aaatatacgg actggtggga cataacggat ctggaaaaac agttttattt
    13261 aaaataatat gtggttttct tgtatccgat gagggaactg ttacggtaaa tgggaaaata
    13321 atgggaaaag acaaagatat gcttacagaa gcgggaatta ttattgaaga tcctggattt
    13381 ttaagaaact ggagcgcata tcataacctg gaatttctat atacaataag aaataaaaaa
    13441 gataagtcat atttatattc gatattaaaa aaagttggtc ttaatccgaa attaaaacga
    13501 ccggtaggaa agttttcact cggtatgaga caacgtctgg caattgctca agcaatcatg
    13561 gaagatccgg aaattcttat tttagacgag ccgatgaatg gacttgataa aaatggtgtg
    13621 gaagaaatca gggaactatt gttaaaaatg aaaaaaaata aattgattat tttggcaagt
    13681 cataacagag aagatataga tgttctctgc gacgaggtat atgaaatgga agacggggta
    13741 ctacggaaaa attcaaatgt gaaatcagta actgataaaa gttactgttt accggaggta
    13801 taaattaacg gattacatat cagtgtagtg tatatattag tttttagaga tcgttttcag
    13861 gacagctcct cttgactact actcatattt tttgatctga aaaacacatc ttattttttc
    13921 aaaataattt gaataattgc gcgtcgcatt ctcgttactt tagcctgatg agttagacgc
    13981 gcaaattttt tacccaaagg aaaacatatg tttattttta gcgctatatg tgctaaaata
    14041 tagccatggg tagtagaaaa aacaacagaa tctgagaaaa gagttatcag ggaaaaataa
    14101 aaatgcagat aatatccagt tatggtgtag aattacgaaa acagaatatc ccgatccgcc
    14161 agacactgga gatctaccgt tctgctgtca gctatctgat tgggatttat gtgcaggtat
    14221 gggaagaatt agcagaaatc ccggatgcaa agaggcgttt taatgctgca gaacatctgg
    14281 tacatactac gaagaaaaac catgcctgtt ttgattttga tatccggttc ccaaagatgc
    14341 cttcctatct gcgcagatct gccatccagc atgcactggg gacagtatcc tcttataaaa
    14401 cacggctgga tctatgggaa aagaccgacg gaaagagcgg gaaaccaaag cttgtatatg
    14461 aaaatcacgc catgccggtc ttctaccgtg atgtcatgta ccgtgaagga gcggaaggga
    14521 aagacgaagc atacctgaaa ctctatgacg gtcatgactg gaaatggtcc tgtgtacgtc
    14581 tggatcatac ggatatggaa tatctgagaa aatgctggtc agggaaaaag gcatctgccc
    14641 cgactctgga aaagagacac cagaagtatt ttttgcgttt ttcctataaa gaggaagtaa
    14701 cacttaccaa aacacctgtg aaagaacaga ttatctgcag cgtggactta gggatcaata
    14761 ccgatgcagt cagtaccatc atgcgggcag acggaactgt cctgggaaga agattcatag
    14821 atcatcccag tgaaaaagac cggatgtacc gtacactggg acggatccgc agattccaga
    14881 gggaacatgg ctctgcgcag acacagggaa gatgggcata tacgaaacgt ctgaacacag
    14941 aactgggtaa aaagactgca ggtgcgattg taagatatgc ggaagaaaac catgcagatg
    15001 tgatcgtgtt cgagtatctg gagatgcagg ggaagatatc gggaaagaaa aaacagaaaa
    15061 tgcacctgtg gagaaaaaga gatatccaga agtgttgtga acatcaggca cacaggaaag
    15121 ggatgcgggt atccaggatc tgcgcatgga ataccagcag actggcttat gatggttccg
    15181 gggcggtaac acgtgactgg gaaaatcaca gcctctgtac tttccagaca ggaaaacgat
    15241 ataattgtga cctgtcagca tcctataata taggggcgag atattttata agggaacttt
    15301 taaaacccct tccggcaacg gaaaggtctt tactggaggc aaaagtccct cctgtaaagc
    15361 gtagaacctc atgcgtttat gcagatctga gaaaactcca ttcagaaatg gaactcttaa
    15421 aagcagcata gatacaggca gatatacagc ggactacctg taatgtggga accagccata
    15481 tctggcatgg aaaaagcaca taactgtgca gacctaagtt acaggcgtat ccgccgatat
    15541 ttagtctgac gcctaaagcg tccggaagca cgtgacttta gccatgtgag gttcacctgg
    15601 aactatttta tgtaagcgct ataaaataga agttgtatta actgcaatta agccttatac
    15661 taaagctatc ttcagaatac aaaagtgcag aagtaagaca ctggcgtata ttatgccgga
    15721 ctcttttctg caaaattaaa ggagtaatcc tatgcagaca tctaaagatt ttttacatat
    15781 ttttcttgat atgggtgacg cattgttaaa cagcggtgca gagatttttc gagtggagga
    15841 tacgctgaac cgaatgggtt atgcctgtgg tgctgcacag atgaatgttt ttgtgatcac
    15901 atccagtatc gttattacca tggaatttcc agaagaagga gcgcggacac agacccgacg
    15961 gatcagggaa agtggtggaa atgattttac aaaattagag cagttgaatg atctgagccg
    16021 tcgtttctgt aatcatcctg tccctgcggc agagcttcgg aaagaatttg ataaaattaa
    16081 cataaatagg acgaaaccgt tatggaaact tcttggaagc cttctggctg catgcagttt
    16141 tgcttttttt tatggtggaa gtattccgga tgctgttgca gcaggatttg gggctgttct
    16201 gatctgggga ttacagcaat atcttcgtcc ggtatgcatg aatgaagtga cttttcagtt
    16261 tgtggcgtct ttttttacag gctgtgcaat ctgtggatta accttgctgt gcccattcct
    16321 tcgcatggat aagattatga tcggtgacat tatgcttttg attccggggt taatgtcgac
    16381 aaatgcaatc agggatgtac ttattggtga tacactctct ggaatcatcc gtctgattgc
    16441 tgctttacta cttgctgcgg cactggcact tggatttatg ggggcaatta ttttatttgg
    16501 gaggtttgga ctttgactgc agcaatcatg atacaattaa ttaccggagc cattggctct
    16561 gtaggatttg gaattctttt tcatataaaa aagaaatatt tgcctctggt agcagttggc
    16621 ggcttcctta gctggctggt gttccttctg ggaaaagaat tctggggaaa tgtttttctt
    16681 ccgactctga tggctggctt tgttacagat gtgtatgcag aaattcttgc aagaatctgt
    16741 aaagaaacat ctacatcttt ttttgttact tccgtaatcc ctctgattcc cggaagtact
    16801 ctttattatt gtatgaacag cattgtggaa ggaaatactg ttcgagcatt ggaatatgga
    16861 cgggatacgt ttctttttgc ttttggaatt gcagcaggaa tgagtattgc gtggtcgatc
    16921 tgttattttc tgagaactgt aaggaaaaag cagaactgac ctggcaagaa agaaattccc
    16981 gatgaaatga cacacacccg ttttcgacag ttgatgaaaa atcacgacca ccggcttagc
    17041 cggtggtcgt gattactgaa tcaagcaagt agcgaagcgg atgattttat ccgcttgacc
    17101 atattatata tgctgtgacg caaatagcaa ggcgaactgt aaactgagaa aataaaaaaa
    17161 gttgacaatt aaccttctgt gttttaaaat agtaaaccat aaaatatatg gaggtttaca
    17221 aatgactaaa acaaaaagca tgatctattg cggtcttttt acggcgttga ttgcagcagg
    17281 tgcgtttatt aaaatccctg tacctgtagt tccctttaca ctgcagtacc tgttcactat
    17341 gcttgccgga ttgtttctgg gatccagaag gggtatgatt tctgtggttg cctatatgct
    17401 gttgggactg gcaggacttc cgatcttttc ggagggcggt gggatctggt atattttcaa
    17461 gccaagcttc ggttatatta tagggttctg cttgggaaca tacgtaaccg gacttatcgc
    17521 agaacgtctt aagcagaaga cagtttttcg ctatttactt gcaaatctgg caggtctgat
    17581 gattgtctat atctgtggaa tggtttatta ctatgtgatc tgtaactatg tgattgatac
    17641 accgattgga atctggccgc tgattcttta ttgttttctg cttgcggtac ccggcgatat
    17701 tgcattaagt atcctgggag ctgtcattgc aaagcgtgtc agaccggtag tgcatcaata
    17761 tctttttgat tcaaaatcaa atgtcagact gaaaacggag gagcttgcaa aatgaatcca
    17821 cttattttag cacaggaaat tattgatggg cgcagaatta caagggagga tgatctttcc
    17881 tattttctta cctgtgattt agacgaatta tgtgaaggag cagaccgtat ccgcgaagca
    17941 tatatcggtg ataaggtgga tctctgttcc atcatcaatg gccgcagcgg caggtgtccg
    18001 gaggactgca aatattgtgc gcagtcagta caccaccata cttcctgtga gatctatgat
    18061 tttcttccgg aggaaaagat tctggaagca tgtaaaatga acgaagagga gggcgttgac
    18121 cgtttctcaa tcgttactgc aggaaaggcc ctgactggaa aagaatttga tcaggcgatc
    18181 cacgcctatg aaaccatgca taaggaatgt aatattgatc tctgtgcttc catgggcttt
    18241 ctttcttctg aacaactgca tcgtcttcat gaagccggag taaccagtta ccatcataat
    18301 attgagactt caaagagaaa ttttcctaat atatgtacga cacatacata cgatatgaag
    18361 attgaaactc tgaaaaaggt aaaggcagaa ggaatgtgtg catgttctgg cggtatcata
    18421 ggaatgggag agacctggga ggatcgtctg gatatggcag tcagccttgc ggagctgggg
    18481 attgattcta ttccaatcaa tgcattgatg cccattccgg gaacaccttt ggaacacctt
    18541 gatcagcttt cagagcagga tatcctccgg acaatcgcct tcttccgtta tattaatcct
    18601 gaggctaata ttcgtcttgc tgccggacgg gcacttctta ccaatgacgg ggaaaccgct
    18661 tttaaatccg gtgcctccgc tacaataaca gggaatatgc tgactactgt tgcctgcgca
    18721 accatccgca gcgaccgaaa aatgctctct gatatgggca gaaatgtaac accagaatat
    18781 tggaaggaag tggaagaatc atga
//
