LOCUS       NZ_CP102267.1          19867 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP102267.1 Blautia wexlerae DSM 19850 chromosome, complete
            genome.
ACCESSION   NZ_CP102267
VERSION     NZ_CP102267.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:24:05
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 658395
            Orig. end    :: 678262
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..555
                     /locus_tag="ctg1_557"
                     /transl_table=11
                     /translation="MKAAVFFPGIGYHCDKPLLYYSRKLAQECGYEETIALSYTYDGGN
                     IRGNEEKMQQAFESLYEQAEKSLSAIDFDKYDEILFVAKSVGTIIASAYAEKHSIRCRQ
                     ILYTPLKYTYNFVHRDAIAFIGTSDPWSIVPEVQALSQKQQVPMYTYKNANHSLETTDT
                     LENLKILQDVMGKTKGFLERK"
     protocluster    1..19867
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[668077:668946]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9683..10551
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..19867
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..19867
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             710..1333
                     /locus_tag="ctg1_558"
                     /transl_table=11
                     /translation="MNFQDQIQQIFGTTDIHELKQISRDADNYRCLNADMNNSIISEKK
                     KNTGRKNSFTEEQLAHILALQDRGEKITDIARQYHVSRQTIYSQIKRAYNFSDDPDVKM
                     RMNFMNHDDLCTTIDIDFRHEKIKIKNYTDQIIFRAFGVVTDPDWADFEYFLEERCFPR
                     TRDHRKDILREMGLPFYDPLLIIEKTQGRMSDDHQWIMILKKEG"
     PFAM_domain     854..970
                     /aSDomain="HTH_7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02796.17"
                     /description="Helix-turn-helix domain of resolvase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_558_0001"
                     /evalue="2.10E-08"
                     /label="ctg1_558"
                     /locus_tag="ctg1_558"
                     /protein_end="87"
                     /protein_start="48"
                     /score="34.2"
                     /tool="antismash"
                     /translation="GRKNSFTEEQLAHILALQDRGEKITDIARQYHVSRQTIY"
     CDS             1340..2161
                     /locus_tag="ctg1_559"
                     /transl_table=11
                     /translation="MEIRNFDAYSPLHKSGHTSKGDQLKWKIDDRWYKADYMGYEGLSE
                     VLVSDLLQKSTCPFPFVEYEAAVIEYNGKIFQGCSSLDFLKANQVLIPLEKLYRRYTGE
                     SLAVKLSDFADVSERIQYLVTQVEEITKIDNFGAYLTAMLEIDAFFMNEDRHTNNIAVI
                     YNEKTQKYELSPFFDQGLCMFADINQDYPIDQSLEYCLEKIEAKPFSSDFDIQLDAAEE
                     LYGIQIGFQFTFKDIQIYLQKNSENYPREVIRRVEQLLRGQMRKYGYLMKK"
     CDS             complement(2269..2442)
                     /locus_tag="ctg1_560"
                     /transl_table=11
                     /translation="MLVCDYIVESIDGDYAHLRRTDLPEEELKLVARALLPFEITEGCR
                     LHYEMMQYSIID"
     CDS             2600..2815
                     /locus_tag="ctg1_561"
                     /transl_table=11
                     /translation="MSKVVKLSSVMEREEKLKEIYEGLEEIKDQLTALIDEYEEEETHT
                     GKADELIEALDALEDASETIEDVLEN"
     CDS             2815..3714
                     /locus_tag="ctg1_562"
                     /transl_table=11
                     /translation="MKEKAYFHLPGLFEFYELYRMFLPLFREHREYFYDWCEIGSIYGA
                     PADCIWGGGRAGFGENDPEEVLELMQEYGISARLTFSNSLLRQEHLSDRKCNALCRLFE
                     RNREPQNGVIIYSELLLEYIKEQYPGLYFVSSTTKVLTDFTQLEEEIRRKDFHYVVPDF
                     RLNKAFDKLNTLSQAEKDKVEFLCNECCWFGCRDRKACYETVSRKNLGENCLEHYCKAP
                     ERERGYLFSKAIENPGFIGINDIRDIYLPMGFSNFKIEGRGLGSALILEFLLYYMTRPE
                     YQIHVREKIYLDSMLDLF"
     CDS             3916..4245
                     /locus_tag="ctg1_563"
                     /transl_table=11
                     /translation="MAIEKSLVSGSMTMLILKLLSEKDMYGYEMIDTLRQKSQNVFELK
                     AGTLYPLLHSLEDKGFLTVYEQEAAGKTRKYYSLTGQGRGFLEKKVEEWKEYSAAVTNV
                     LVMEV"
     PFAM_domain     3961..4179
                     /aSDomain="PadR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03551.16"
                     /description="Transcriptional regulator PadR-like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_563_0002"
                     /evalue="3.00E-23"
                     /label="ctg1_563"
                     /locus_tag="ctg1_563"
                     /protein_end="88"
                     /protein_start="15"
                     /score="81.7"
                     /tool="antismash"
                     /translation="ILKLLSEKDMYGYEMIDTLRQKSQNVFELKAGTLYPLLHSLEDKG
                     FLTVYEQEAAGKTRKYYSLTGQGRGFLE"
     CDS             4249..5781
                     /locus_tag="ctg1_564"
                     /transl_table=11
                     /translation="MDEYLKTLLEQIRCKKARPYVKQEFQDHIEDQIEANMQAGMDREQ
                     AEREAVRDMGDPVETGISLDSVHRPQVAWKLLGIIVLISIAGVLIHAGIAGKISENAAA
                     GSDRYVFHVVIGLAVMMILYLLDYTVLARFSKIIAVILLFACLVTLLGGYQLNGARCFI
                     VLPGGRGISMQTLMLFYVPIYGAILYKYHGWGYKGLIRAIIWMFAPVILVYAMPALMTA
                     CVMLVSMLVMLTIAIQKNWFTVRKRRAICGIWAGFLAMPVAAFLIRYLRSSLTKYQIAR
                     LQAVFSGGGEEDYFTEMLHSFWQQNKWIGKSESDVMGNLPAFNADYILTYLSSVYGTIA
                     AIFLCCVLAVLIFAVFNTAMRQKNQLGMMMGCGCGIVFLINFFINILENLGIFPQSVTF
                     LPFLSAGGSCIIVSYGLMGIVLSTYRYKNIYPRHLKIGFKFDKTKARKALYVSKMSMCI
                     WTGGTVVVMCVAIYWDLCKSYMNIPFKIVTIVLTLLLVGNMRKIVQHNEMNR"
     PFAM_domain     4474..5529
                     /aSDomain="FTSW_RODA_SPOVE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01098.21"
                     /description="Cell cycle protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_564_0003"
                     /evalue="1.00E-20"
                     /label="ctg1_564"
                     /locus_tag="ctg1_564"
                     /protein_end="427"
                     /protein_start="75"
                     /score="74.2"
                     /tool="antismash"
                     /translation="LLGIIVLISIAGVLIHAGIAGKISENAAAGSDRYVFHVVIGLAVM
                     MILYLLDYTVLARFSKIIAVILLFACLVTLLGGYQLNGARCFIVLPGGRGISMQTLMLF
                     YVPIYGAILYKYHGWGYKGLIRAIIWMFAPVILVYAMPALMTACVMLVSMLVMLTIAIQ
                     KNWFTVRKRRAICGIWAGFLAMPVAAFLIRYLRSSLTKYQIARLQAVFSGGGEEDYFTE
                     MLHSFWQQNKWIGKSESDVMGNLPAFNADYILTYLSSVYGTIAAIFLCCVLAVLIFAVF
                     NTAMRQKNQLGMMMGCGCGIVFLINFFINILENLGIFPQSVTFLPFLSAGGSCIIVSYG
                     LMGIVLSTYRYK"
     CDS             complement(5858..6166)
                     /locus_tag="ctg1_565"
                     /transl_table=11
                     /translation="MFKEAICLAKPNIELNAEKTTAMLYTLADKFLDRTELDEIKEVMR
                     MTRLGQMLMDEGMELKETDSIKKLMKNMNLTIDQAMNALEVPADKREKYRKTITPDN"
     CDS             complement(6308..7435)
                     /locus_tag="ctg1_566"
                     /transl_table=11
                     /translation="VILHKKKDTLNRLCCIMKVTKQTLQHLRKKVPLTNTIHYSTFIYN
                     QLKKLNLCKSFSNRVIGHLMSILISIFISGYHGKTTDFSQNSSCPRTTIAHFLNSGKWD
                     DTLLENTLKSSVVEIIYSEAQRTGKPVFCIVDDTIASKTKPSSQAMHPIEDAYFHQSHL
                     KRKQDYDHQAVAVMLSCNGIVLNYAFVLYNKSISKIDIVQNIAKELPEPPVMSYFLCDC
                     WYVSEKIINTFVQKGFHTIGALKTNRLLYPSGMKKKLSELAAELSVTEKGFDPVTVKNR
                     KYYVCRWTIGVFFRQCKTRLALDTYQIRSSKGIQRYWLLMSMAHYICVISTGQYQSFQE
                     GYQLIRSTIQQEKYQYLFQCAKSCVDFEAFMKLAG"
     PFAM_domain     complement(6461..7051)
                     /aSDomain="DDE_Tnp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01609.23"
                     /description="Transposase DDE domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_566_0004"
                     /evalue="1.80E-09"
                     /label="ctg1_566"
                     /locus_tag="ctg1_566"
                     /protein_end="325"
                     /protein_start="128"
                     /score="37.7"
                     /tool="antismash"
                     /translation="KPVFCIVDDTIASKTKPSSQAMHPIEDAYFHQSHLKRKQDYDHQA
                     VAVMLSCNGIVLNYAFVLYNKSISKIDIVQNIAKELPEPPVMSYFLCDCWYVSEKIINT
                     FVQKGFHTIGALKTNRLLYPSGMKKKLSELAAELSVTEKGFDPVTVKNRKYYVCRWTIG
                     VFFRQCKTRLALDTYQIRSSKGIQRYWLLMSMAH"
     CDS             7517..8296
                     /locus_tag="ctg1_567"
                     /transl_table=11
                     /translation="MDKNNRVIYGIAGDGEIMRVVICDDEKVTCSEIEKMLSFFAFEKC
                     IKLEVDVFFDGDTLTEYLKKEKAPDILFLDIELPGMNGVEVGKYIRDILRNTDMFMIYI
                     SSKKEYALELFQNQPFDFLIKPIKKERLYHVMEKIFSIIGKNECNFEYKNQGNSYRIMY
                     KDILYFQSDGRKINIVMEKKIESFYGKLSEIEQMCPEGLFLRIHKSYLINMCHAKEITY
                     KWIKMINGDVLDISRSNRVAIRRKLMESMANEIRNDS"
     PFAM_domain     7574..7921
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_567_0005"
                     /evalue="9.50E-17"
                     /label="ctg1_567"
                     /locus_tag="ctg1_567"
                     /protein_end="135"
                     /protein_start="19"
                     /score="61.3"
                     /tool="antismash"
                     /translation="VVICDDEKVTCSEIEKMLSFFAFEKCIKLEVDVFFDGDTLTEYLK
                     KEKAPDILFLDIELPGMNGVEVGKYIRDILRNTDMFMIYISSKKEYALELFQNQPFDFL
                     IKPIKKERLYHV"
     PFAM_domain     7988..8257
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_567_0006"
                     /evalue="1.10E-16"
                     /label="ctg1_567"
                     /locus_tag="ctg1_567"
                     /protein_end="247"
                     /protein_start="157"
                     /score="60.9"
                     /tool="antismash"
                     /translation="SYRIMYKDILYFQSDGRKINIVMEKKIESFYGKLSEIEQMCPEGL
                     FLRIHKSYLINMCHAKEITYKWIKMINGDVLDISRSNRVAIRRKL"
     CDS             8274..9557
                     /locus_tag="ctg1_568"
                     /transl_table=11
                     /translation="MKFVMIAELLLILFSNGIRFYAVKRYIDFFAAREKCLWKYNWILY
                     TFACIGTYIVSIIFESPNLNIISNVIALFLLACPYKIKLSKKFLMTFIIYSINLLADII
                     VVQLLAGYVPGQRVGSAYQFITSLAILIPTAFFSEFTKKKTQDSLPLMNVFILGMIPLV
                     SIVCMHSIATLTENNKPVVLTVAFSLILINSFLFYLYYTLTQFYVAKMNEKKLEQIIDV
                     YAHQLDVVQESQEHIKKLRHDMKHHLIELSAMAQQDKNKDMMRYLEHMEKFMLNPAEKV
                     STGNKEIDGVLNYMLRRADELLKIVNLDIQIPKSLYRNNFNICVILGNLVDNAVRESSK
                     SDEKYLSISVRVQKDILIILIENSYSGSIVQKGNIFQTSQIDTSIHGLGLESVKQVVEA
                     CGGDIKIEYTEKRFWVQVLLYLSNIVEN"
     PFAM_domain     9231..9530
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_568_0007"
                     /evalue="2.00E-21"
                     /label="ctg1_568"
                     /locus_tag="ctg1_568"
                     /protein_end="419"
                     /protein_start="319"
                     /score="75.8"
                     /tool="antismash"
                     /translation="NFNICVILGNLVDNAVRESSKSDEKYLSISVRVQKDILIILIENS
                     YSGSIVQKGNIFQTSQIDTSIHGLGLESVKQVVEACGGDIKIEYTEKRFWVQVLL"
     CDS             9683..9829
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_569"
                     /sec_met_domain="TIGR04223 (E-value: 5.6e-07, bitscore:
                     27.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKDILKLGMKIVKNTAIKLAERDANTTCPYYGYQAELPCAVKKL
                     KKP"
     aSDomain        9710..9814
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_569_0001"
                     /evalue="5.90E-07"
                     /identifier="TIGR04223"
                     /label="ctg1_569"
                     /locus_tag="ctg1_569"
                     /protein_end="44"
                     /protein_start="9"
                     /score="27.5"
                     /tool="antismash"
                     /translation="MKIVKNTAIKLAERDANTTCPYYGYQAELPCAVKK"
     CDS             9985..10551
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_570"
                     /sec_met_domain="AgrB (E-value: 8.3e-36, bitscore: 121.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHRKKFSIRLIEKIGHDEEEREIIQYGLHQGFLILLNLLTTVV
                     CGILWKELPFVLLVFWGIFFLRPYAGGYHADTELRCYFLSTAMMNMVVFLKKTIVLSNI
                     MFIIIWIITVIFIWIYAPVENTIHCLDEDARKKYANNTKKILLCNGIVMLVGIWVNQRI
                     VVDAIIWSQVMIAIAMIAGLWKYST"
     PFAM_domain     10018..10524
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_570_0008"
                     /evalue="4.30E-35"
                     /label="ctg1_570"
                     /locus_tag="ctg1_570"
                     /protein_end="180"
                     /protein_start="11"
                     /score="120.8"
                     /tool="antismash"
                     /translation="LIEKIGHDEEEREIIQYGLHQGFLILLNLLTTVVCGILWKELPFV
                     LLVFWGIFFLRPYAGGYHADTELRCYFLSTAMMNMVVFLKKTIVLSNIMFIIIWIITVI
                     FIWIYAPVENTIHCLDEDARKKYANNTKKILLCNGIVMLVGIWVNQRIVVDAIIWSQVM
                     IAIAMI"
     CDS             10763..11140
                     /locus_tag="ctg1_571"
                     /transl_table=11
                     /translation="MRKIIKRTLCVLSATMCVLGTAATASADTVSFNVTIPGDPYSYAV
                     RKADTEQRFYVTGTSFNKSGTLRCRSGKAGQGTSSNSAYISSGSRASSASYTSYAAPNY
                     TYEMYATSGTSGLNVRGRFTP"
     CDS             11197..12288
                     /locus_tag="ctg1_572"
                     /transl_table=11
                     /translation="MRKGLRQAMIVLGICMCLGGCEKETEAKTEPEGETVQSEDGDFFP
                     ESYSEETEKVKFECVVNVPEKFEVTNFHAPIIKGVSNIDAETAYKKYVEGKVVTEEYHD
                     EPTIENEKGNDTYILEDGTVIGLSGVFLYNTPESSIYRQVVRMSERSAPKDNFKFASGD
                     DCTEQVKEELRSLGCPVDEYQFDWFSTSGEDYAILEKRALDDGMIDSQRAKQDGWTEAN
                     NSYEIYGWQLYEGLQVLPPWITSAMSRAFESYQKAPISAVYTKQGMLSLALTEAPCIFE
                     HSDETLEFLKFPEIADILEEKYSALLDDAVYTVTYAKLVLRTYFDEGQKLAAEPVWYFE
                     VTDGTSMEVALLNAVTGTEIFLN"
     CDS             12337..13107
                     /locus_tag="ctg1_573"
                     /transl_table=11
                     /translation="LQCFINYLRTDFRRLGKSYRWLAGIVGVVAILFFSLESVLFQKGL
                     ENGNVLSTYVYSTNMTGFLIAYSFCAFPFAGVYPEEQEHKYIRYNVIRGSLKSYVLSKT
                     TVIYISSLSIMILGSVLFLFLCRTYVPWTDWSIDSYGIELNGCYGSILEEGHVILYCTL
                     YALNLGLIAGALSNMAALCSVFISNTVLVLVFPVLAFRVLVSVNIADYNIYAFYAYTKI
                     FASDGVNLLFLTVISVGISALSAAGCYWGLKKKM"
     CDS             13123..14001
                     /locus_tag="ctg1_574"
                     /transl_table=11
                     /translation="MKTLKYIMKTSAQKIFNVKFATFCAAFLILSWTYDQPYLQFVKEK
                     NYPISWCIFPFYMSSFGILSIFYVGIVYIHSDVPFMQHINMYQVIRTGRERWALSQIAG
                     ILIRSFFAVILSAIAAVLPFWGHIEFSTDWGKVIKTLASQRADEGFGFGMGQMLDFRFH
                     YGILGKFTPVQLMIITVLICTLICTFLGILMFLISLYAGKILAVAVTMMSVVALFIVEN
                     IYGEWKLIVAHVVPTYWAEVALSATPVSGRYRIPSLTYIFTFLIVAVVFMSVIIFCKVK
                     HTEFHWENEDA"
     CDS             14026..14670
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 162.4; E-value:
                     2.3e-49)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_575"
                     /transl_table=11
                     /translation="MEKQRIEVNHVFKSFKEKEVLKDVSLTCESGKIYGIVGHNGSGKT
                     VLFKCICGFFYCDRGEIRVNGKCMGKDADMLQNAGIIIEEPGFLRQWSGFHNLEFLYTI
                     RNKLNKKYMYSVLEKVGLEPRSKIPVGKYSLGMRQRLAIGQAIMENPDILILDEPMNGL
                     DKNGVQEMRGLFEQMKNEGKLIILASHNREDIDVLCDEVYEMENGILKKRR"
     PFAM_domain     14086..14508
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_575_0009"
                     /evalue="6.40E-27"
                     /label="ctg1_575"
                     /locus_tag="ctg1_575"
                     /protein_end="161"
                     /protein_start="20"
                     /score="94.8"
                     /tool="antismash"
                     /translation="LKDVSLTCESGKIYGIVGHNGSGKTVLFKCICGFFYCDRGEIRVN
                     GKCMGKDADMLQNAGIIIEEPGFLRQWSGFHNLEFLYTIRNKLNKKYMYSVLEKVGLEP
                     RSKIPVGKYSLGMRQRLAIGQAIMENPDILILDEPMN"
     CDS             14696..14884
                     /locus_tag="ctg1_576"
                     /transl_table=11
                     /translation="MIIPYEIFKENKRFKESIDNAQNETDILLYNAAKEYSNSVRKRAK
                     AVTDIIMERIEKEIKNS"
     CDS             15091..16305
                     /gene_functions="other (smcogs) SMCOG1130:transposase
                     (Score: 475.3; E-value: 1.8e-144)"
                     /gene_kind="other"
                     /locus_tag="ctg1_577"
                     /transl_table=11
                     /translation="MAVAKEQIRQIISENNINSVADIYTLLKDSFKDILQELMEAELDA
                     TPGYEKNHKGDLQTDNKRNGHSTKNLKSQYGEFQIDVPRDRNGEFEPKLIPKYQRDISG
                     IEEKVISLYARGMSTRDIHDQLQDLYGIELSAEMVSKITDKILPQVKEWQSRPLNPVYP
                     FVFMDCIHYKVREDGRILSRAAYVVPGVTVEGYKDILSITAGANETSKFWLGMLNDLKN
                     RGVKDVLFFCVDGLPSFKEAIQAVYPQAEIQRCVIHMLRNSFKYVNYNDLKKFSSDFKE
                     VYNAPNETAALTELENMKEKWGKKYPYAISNWENNWEDVSSFFQFSNDIRRIMYTTNII
                     EGLNRQYRKVTKTKSVFPSDPALEKMLYLASENVVKKWTQRYRNWDQVLNQLIVLYGER
                     LTAYL"
     PFAM_domain     15118..16230
                     /aSDomain="Transposase_mut"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00872.20"
                     /description="Transposase, Mutator family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_577_0010"
                     /evalue="8.10E-113"
                     /label="ctg1_577"
                     /locus_tag="ctg1_577"
                     /protein_end="380"
                     /protein_start="9"
                     /score="377.2"
                     /tool="antismash"
                     /translation="QIISENNINSVADIYTLLKDSFKDILQELMEAELDATPGYEKNHK
                     GDLQTDNKRNGHSTKNLKSQYGEFQIDVPRDRNGEFEPKLIPKYQRDISGIEEKVISLY
                     ARGMSTRDIHDQLQDLYGIELSAEMVSKITDKILPQVKEWQSRPLNPVYPFVFMDCIHY
                     KVREDGRILSRAAYVVPGVTVEGYKDILSITAGANETSKFWLGMLNDLKNRGVKDVLFF
                     CVDGLPSFKEAIQAVYPQAEIQRCVIHMLRNSFKYVNYNDLKKFSSDFKEVYNAPNETA
                     ALTELENMKEKWGKKYPYAISNWENNWEDVSSFFQFSNDIRRIMYTTNIIEGLNRQYRK
                     VTKTKSVFPSDPALEKMLYLASENVVKKWTQ"
     CDS             17011..17577
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 59.5;
                     E-value: 5.7e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_578"
                     /transl_table=11
                     /translation="VEDTVIINLYFDRSEKAIQATEEKYSRYCFSIAWNVLYDKEDSNE
                     CVNDTWLATWNSIPPRKPAILSAFLGKITRNLAIDCFRRKKAAKRSTEHILELCKELEE
                     IEDVTAYSLNDEIQRKEILEILEKFLESLKKGDCDIFIRRYWYMDSISEISARHGISES
                     RIKSSLYRSRKKLWERVKHLYGKRI"
     aSDomain        17068..17541
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_578_0002"
                     /evalue="9.80E-20"
                     /identifier="TIGR02937"
                     /label="ctg1_578"
                     /locus_tag="ctg1_578"
                     /protein_end="177"
                     /protein_start="19"
                     /score="68.8"
                     /tool="antismash"
                     /translation="ATEEKYSRYCFSIAWNVLYDKEDSNECVNDTWLATWNSIPPRKPA
                     ILSAFLGKITRNLAIDCFRRKKAAKRSTEHILELCKELEEIEDVTAYSLNDEIQRKEIL
                     EILEKFLESLKKGDCDIFIRRYWYMDSISEISARHGISESRIKSSLYRSRKKLW"
     PFAM_domain     17077..17268
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_578_0011"
                     /evalue="2.70E-08"
                     /label="ctg1_578"
                     /locus_tag="ctg1_578"
                     /protein_end="86"
                     /protein_start="22"
                     /score="33.6"
                     /tool="antismash"
                     /translation="EKYSRYCFSIAWNVLYDKEDSNECVNDTWLATWNSIPPRKPAILS
                     AFLGKITRNLAIDCFRRKK"
     PFAM_domain     17380..17538
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_578_0012"
                     /evalue="3.60E-07"
                     /label="ctg1_578"
                     /locus_tag="ctg1_578"
                     /protein_end="176"
                     /protein_start="123"
                     /score="29.9"
                     /tool="antismash"
                     /translation="EILEKFLESLKKGDCDIFIRRYWYMDSISEISARHGISESRIKSS
                     LYRSRKKL"
     CDS             17561..18691
                     /locus_tag="ctg1_579"
                     /transl_table=11
                     /translation="MEKGFKTLELIGDLDDKYIYEASKPWKKQHRFFHIQRSWKTAVAG
                     IILLIMVGCTLRYQEDVKAALQRVTSWIGQALGIKNGDTDSYTNVVGKSISRDGITITL
                     NEIVMDSKNLWIAYYDSEDSDADMKDAVEDKLLYTEVCINGQEIQQGLGQRTVNAFSEN
                     PITVEDFTIGEEVNTEGTVNIEFKVWPIAMDDADTWENVQKIQADTEPYTFKLATSKEE
                     LEKNTVDLNLNQNIKMDSNVLNLTEFRWNPFESTIYGMYHGTVYIDSDYYLIGTDDQGN
                     KICYQETGRNGQETMFRQTIGLYPGYEEISPEANTITLQLYEVKNDTAHQVSEEKMDKD
                     PSDDIYEESTVYVYNEGESPTDDAIPIGDKFTVQIR"
     PFAM_domain     17669..17914
                     /aSDomain="DUF4179"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13786.8"
                     /description="Domain of unknown function (DUF4179)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_579_0013"
                     /evalue="2.80E-09"
                     /label="ctg1_579"
                     /locus_tag="ctg1_579"
                     /protein_end="118"
                     /protein_start="36"
                     /score="37.4"
                     /tool="antismash"
                     /translation="RSWKTAVAGIILLIMVGCTLRYQEDVKAALQRVTSWIGQALGIKN
                     GDTDSYTNVVGKSISRDGITITLNEIVMDSKNLWIAY"
     CDS             18688..19116
                     /locus_tag="ctg1_580"
                     /transl_table=11
                     /translation="MKMKKTYYLNKDVLPTIPVPHDCIIKKIRIEHKWLIFTFDNDTSY
                     YDSVRKLSPNIRNLILKYHLSNPEDFSVYKCSKTLKRILNKECYIRQNTRKITKLPRKR
                     LEYLYHNVGYCSIITKLHSDAPVMIDAGVDYLVYEWIE"
     CDS             19208..19867
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 176.7; E-value: 8.5e-54)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_581"
                     /transl_table=11
                     /translation="MKNKILVIEDDRAISELLCMNLTIAGYETVAAYDGIEAQRLLLWN
                     EDADLAVVDIMLPGKDGFALMEDFRAKNLPVIYLTAKDDVASKVKGLKLGAEDYMVKPF
                     EMLELLVRIEKILERTGRAKRILTIKNIQADLQSHQILKDGIPVNLKPLEYDLFILLLQ
                     NKNIALGREELLKRVWGEEYLGESRTVDVHIGQLRKKLELYDEIKTIPKLGYRLED"
     PFAM_domain     19220..19546
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_581_0014"
                     /evalue="8.90E-21"
                     /label="ctg1_581"
                     /locus_tag="ctg1_581"
                     /protein_end="113"
                     /protein_start="4"
                     /score="74.2"
                     /tool="antismash"
                     /translation="ILVIEDDRAISELLCMNLTIAGYETVAAYDGIEAQRLLLWNEDAD
                     LAVVDIMLPGKDGFALMEDFRAKNLPVIYLTAKDDVASKVKGLKLGAEDYMVKPFEMLE
                     LLVRI"
     PFAM_domain     19646..19858
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_581_0015"
                     /evalue="1.20E-20"
                     /label="ctg1_581"
                     /locus_tag="ctg1_581"
                     /protein_end="217"
                     /protein_start="146"
                     /score="73.4"
                     /tool="antismash"
                     /translation="PVNLKPLEYDLFILLLQNKNIALGREELLKRVWGEEYLGESRTVD
                     VHIGQLRKKLELYDEIKTIPKLGYRL"
ORIGIN
        1 atgaaggcag cagtattttt ccctggtatt gggtatcatt gtgacaagcc acttttatat
       61 tattcacgaa agctggcgca ggaatgtggc tatgaagaaa caattgcatt aagctatact
      121 tatgatggcg gaaatatccg gggaaatgaa gaaaaaatgc agcaggcatt cgaaagcctt
      181 tatgaacagg cagagaaaag tctttctgcc attgactttg acaaatatga tgaaatatta
      241 tttgtcgcaa aaagcgtagg cacgatcata gcatccgcat atgcagagaa acacagcatc
      301 agatgtcggc agatactata cacaccattg aaatacacat ataattttgt tcatagagat
      361 gccattgcct ttatcggaac ttcagatcca tggagtattg ttcctgaagt acaggctctt
      421 tcacaaaaac agcaggtgcc aatgtatact tataaaaatg caaaccattc actggaaaca
      481 acagatacac tggaaaacct gaaaattctc caggatgtta tggggaaaac caagggattt
      541 ttggagcgga aataagaaaa agcacataat catattgagt agatatgggt gaagaagtgt
      601 caagaaacta tttcttgaca cttctttttg ctccatgcta tactcaatta gacaaactgt
      661 tatatgtgaa agtggtttcc ataatgtctt tttaggtggt gatgtgaata tgaactttca
      721 agatcagata cagcagattt ttggaacaac agatattcat gaactgaagc agatatccag
      781 agatgccgac aattacagat gcttgaatgc tgatatgaat aacagcatta tttcagaaaa
      841 gaaaaaaaat accggaagga aaaattcgtt tacagaagaa cagctggcac atattttggc
      901 actgcaggac cggggagaaa aaattacaga tattgccaga cagtatcacg tttcccgtca
      961 gacgatttac agtcagataa agcgagccta taatttttct gatgatccgg atgtgaaaat
     1021 gcgtatgaat ttcatgaatc atgatgatct gtgtacaacg atagatattg atttcaggca
     1081 tgaaaaaatt aagattaaaa actatacaga tcagattatt ttccgggcat ttggagttgt
     1141 aactgatccg gattgggctg attttgaata ttttctggaa gaacgctgtt ttcccagaac
     1201 acgcgatcac aggaaagata ttctgagaga gatggggctt ccattttatg atccgttatt
     1261 aattattgaa aaaacacagg ggcgcatgtc agatgatcat caatggatta tgattctaaa
     1321 aaaggagggc tgatcaaaaa tggaaattcg caattttgat gcatattctc ccttgcataa
     1381 gagcggtcat acttccaagg gagatcagct caaatggaaa attgatgaca ggtggtataa
     1441 ggctgattat atgggatatg aaggtttatc tgaagttctt gtatctgacc ttttgcagaa
     1501 gagtacctgt cctttccctt ttgttgagta tgaagcagct gtaattgagt ataatgggaa
     1561 aatatttcag ggctgttcca gtttggattt tctgaaagca aatcaggttc tgattccgct
     1621 ggaaaaattg tatcgtcgat atacaggtga aagtctggca gtaaagctct cagattttgc
     1681 ggatgtttca gaacgcattc agtacctggt aactcaggtg gaagaaatta ctaaaataga
     1741 taattttgga gcgtatctga ctgcaatgct ggaaatagat gcgtttttca tgaatgagga
     1801 cagacatacc aacaatattg cggtcattta taatgaaaaa acacagaaat atgaactgag
     1861 tccttttttt gatcagggac tttgtatgtt tgccgacata aatcaggatt atcctattga
     1921 tcagtcattg gaatattgtc tggaaaaaat tgaggcgaag ccatttagct ctgattttga
     1981 tatacagctg gatgcagcag aagaactgta tggcattcag attggtttcc aatttacctt
     2041 taaagatatt cagatatact tacagaagaa ttcggaaaat tatcccaggg aagtaataag
     2101 acgcgtggag cagctgttaa gagggcagat gcgtaaatat gggtatctga tgaaaaaatg
     2161 atattacaga gagtgtatga agttacaggc agataaagga taaaaaagtc acttatctgc
     2221 cttttctggt aaactttttg taacggctgt gaggcggaga ctgtcaaatc agtcaatgat
     2281 actatactgc atcatttcat aatgtaatct gcatccttct gtaatctcaa agggcagaag
     2341 tgcccgtgct acgagtttta actcttcttc aggcagatct gttctgcgaa gatgtgcata
     2401 gtcaccgtca atagattcta cgatataatc acaaactaac ataaaaatcc tccactttat
     2461 attttgcgta acgcaatgat catatctata gaataccaca gaggaaaagg gtatcacaag
     2521 tgccttcaga ttatatagac ataaaaagag ggcagtgtta taatttttcc taaagaaaat
     2581 gcatatggga ggtatcgcaa tgtctaaagt tgtaaagctt tcatccgtaa tggaaaggga
     2641 agaaaaatta aaggaaatct atgaaggtct ggaagagata aaagatcagc tgacagcact
     2701 gattgatgag tatgaagaag aggagacaca tacaggaaaa gcagatgaac tgatcgaagc
     2761 cctggatgct cttgaggatg cttcggaaac catagaggat gtgctggaaa attaatgaag
     2821 gagaaagcat attttcacct gcccgggctg tttgagtttt atgagctgta ccggatgttc
     2881 ctgcctttat tccgggaaca cagggaatat ttttacgact ggtgtgaaat tggctccata
     2941 tatggtgctc cggcagactg tatctggggt ggaggcaggg ctggcttcgg agagaatgac
     3001 ccggaggagg ttcttgaact gatgcaggaa tatgggattt ctgcccgact gactttcagc
     3061 aattccctgc ttcgccagga gcacctttca gacagaaaat gcaatgcact gtgccggttg
     3121 tttgagagaa acagagaacc gcaaaacggc gtgatcattt attcagaatt gctcttggaa
     3181 tatattaagg agcagtatcc gggactctat tttgtttcct ccactaccaa ggttctgaca
     3241 gattttacac agcttgagga agaaatcagg agaaaagatt tccattatgt tgtgccggat
     3301 ttccggctaa acaaggcttt tgataagtta aatacattgt ctcaggctga gaaggacaaa
     3361 gtagaatttc tctgcaatga atgctgctgg ttcggctgca gggacagaaa agcctgctat
     3421 gaaacggtca gccgcaagaa tctgggtgaa aactgcctgg agcattactg caaggcaccg
     3481 gagagagaga ggggctatct tttttcaaaa gctatagaga atccagggtt tattggaatc
     3541 aatgatatcc gggatatcta tctgccaatg ggattttcaa attttaaaat agaaggaaga
     3601 ggactcggca gtgccctgat actggaattt ctgctctatt acatgaccag accggaatac
     3661 cagatacatg tcagagaaaa aatatatctg gacagtatgc tggatctgtt ttgagagatt
     3721 tataccaccg cattgtgtta ctatatgaca atgcggtggt ttttctgtcc gaaaaagtat
     3781 gtagatacct gaactcggtt gccatagcag tgaagttttc aaaattattc cggaaacagt
     3841 tgacatagca tataggttct tatattatat agataaccga tatatagaca atctatacaa
     3901 tgggaggtga atactatggc tattgaaaaa tcactggttt ccgggagtat gacaatgctt
     3961 atactgaaat tgctgtcaga aaaggatatg tatggatatg agatgatcga taccctgcga
     4021 cagaaatctc agaacgtgtt tgaactgaaa gcaggaactc tgtatccgtt actgcacagt
     4081 ctggaggata agggatttct gacagtatac gaacaggagg cagccggaaa gaccagaaag
     4141 tattacagtc tgactggaca gggaagggga tttctggaaa aaaaagtaga agaatggaaa
     4201 gagtattctg cagcagtgac caacgtgctt gtaatggagg tgtgatctat ggacgaatat
     4261 ctgaaaacat tactggaaca gattcgctgt aagaaagcgc ggccttatgt aaaacaggaa
     4321 tttcaggatc atatagaaga tcagatcgag gcaaatatgc aggcaggtat ggatcgtgaa
     4381 caggcagaga gggaagctgt ccgggatatg ggagatcctg tggaaacagg aatctctctt
     4441 gacagtgtcc acaggcctca ggttgcatgg aaacttctgg ggataatcgt tcttatcagc
     4501 attgcaggcg ttttgataca tgcagggatt gccggaaaaa tcagtgagaa cgctgcggcc
     4561 ggttcggaca gatatgtgtt ccatgttgtg atcggacttg cagttatgat gattttatat
     4621 cttctggatt acactgtact ggcaagattt tcgaaaataa ttgccgtcat tttactgttt
     4681 gcctgtctgg ttacattgtt gggtggctat cagttaaatg gggcaagatg cttcattgta
     4741 ctgccgggag gaagaggaat atccatgcag actctgatgc tgttttatgt tcccatatat
     4801 ggagcaattt tgtataaata tcatggatgg ggatataagg gcttgataag agcaatcata
     4861 tggatgtttg caccggttat attggtctat gccatgcctg cgcttatgac agcttgtgtg
     4921 atgttggtat ctatgctggt tatgctgaca atcgcaattc aaaagaactg gtttactgtg
     4981 agaaaaagga gagccatctg tggaatctgg gctggctttc tggctatgcc tgtggcagct
     5041 tttctgatca ggtatctgag aagcagtctg acaaaatatc agatcgcacg tttacaggct
     5101 gttttttcag gtggtggaga agaggattat ttcaccgaaa tgctgcattc attctggcag
     5161 caaaataaat ggatagggaa aagtgaatca gatgtaatgg gaaatctacc ggcctttaat
     5221 gcggattata ttctgaccta tctgtcatct gtatatggaa caattgcagc catattttta
     5281 tgctgtgttc tggcagtttt gatttttgca gtttttaaca ctgccatgcg acagaagaat
     5341 cagcttggaa tgatgatggg atgtggatgc ggaatcgtat ttcttataaa ctttttcata
     5401 aatatcctgg aaaatctggg tatatttcca caatcagtaa catttcttcc ctttttatca
     5461 gcaggaggaa gctgcattat agtttcctat ggactgatgg ggattgtgct gagtacatac
     5521 agatataaaa atatctatcc acggcatctg aaaataggtt ttaaatttga taaaaccaaa
     5581 gcgagaaaag ccctgtatgt ctcaaaaatg tccatgtgca tatggacagg aggcactgtt
     5641 gttgttatgt gcgttgccat atattgggat ttgtgtaaga gttatatgaa tattccgttt
     5701 aaaatcgtaa ccattgtact gacattgctt ctggttggaa atatgagaaa gattgtgcag
     5761 cacaatgaaa tgaacagata gaaaatgtaa gaaactgtat taagaaagat accgccatat
     5821 tgattgtgat aagtcaatat ggcggtactt ttatccatta attgtcagga gtgattgtct
     5881 tgcggtattt ttcacgttta tctgccggaa cttccagggc gttcattgcc tggtcaatgg
     5941 tcaggttcat atttttcata agttttttga tggagtcggt ttctttgagt tccatgccct
     6001 catccattaa catctgtcca agtctggtca tgcgcattac ctccttaatt tcgtctaact
     6061 cagttctgtc taagaacttg tcagccagtg tatacaacat cgcagttgtc ttttcagcat
     6121 tcagctcaat attgggcttt gccagacaaa ttgcttcttt aaacatatcc ttgcggctca
     6181 tttttccgga catcaatggt gtcagggaaa gagcagcgta atcatcttca gtaaaagctt
     6241 caccgttatc ctgcttctgc tttaattatt aagctataaa tgagcaaatt tgaaaaaatg
     6301 cacaaaacta tcctgctaat ttcataaacg cttcaaaatc gacacaggat tttgcacatt
     6361 gaaacaaata ttgatacttt tcctgctgaa tggtactgcg aatcagttga tatccttcct
     6421 ggaaagactg atattgccca gtgcttataa cacagatata atgtgccatt gacatcaaca
     6481 gccagtacct ctggattcct ttcgaggaac gtatctgata ggtatccaac gccagacggg
     6541 ttttacattg tctgaaaaat acccctattg tccaccggca cacataatat tttcggtttt
     6601 tgactgtcac agggtcaaat cctttctctg ttaccgataa ttcagcagca agttcgctga
     6661 gcttcttttt cattcctgac gggtacagca ggcggtttgt ttttaaagct ccaatggtat
     6721 ggaacccctt ctgtacaaat gtgttgatta ttttttcaga aacataccag cagtcacaaa
     6781 ggaaatatga catgactgga ggttctggca gttcctttgc aatgttctgc acaatatcaa
     6841 tcttggaaat ggatttattg tacagtacaa aagcatagtt caggacaatg ccattgcacg
     6901 aaagcataac agcaactgcc tgatggtcat aatcctgttt tctctttaaa tgggactggt
     6961 ggaaatacgc atcttcaatt ggatgcatag cctgtgacga aggctttgtc tttgaagcta
     7021 tggtatcatc cacaatacag aaaacaggtt ttccggtgcg ctgtgcttct gaataaataa
     7081 tttcaactac ggaggatttt aaagtatttt caagtaaggt atcatcccat ttcccagaat
     7141 tgaggaaatg tgcgatggta gttctggggc aggaactgtt ttgtgaaaag tcggtagtct
     7201 ttccgtggta acctgagata aagatactga tcaggatact catgagatga ccgatcactc
     7261 tgttcgaaaa agatttgcat aaatttaatt tcttaagctg gttgtatatg aatgtagaat
     7321 aatgtatagt atttgtgaga ggcaccttct ttcgtaaatg ttgcaatgtt tgtttggtca
     7381 ctttcattat acaacacaaa cgatttaagg tgtctttctt tttatgcaaa atcacgaact
     7441 tgctcattta tagttatatt cttgctaaca tacttctaaa gatgaagttt atgaaaaatt
     7501 gaaaggagta gcttgcatgg ataaaaataa tagagtaata tacggaatag caggagatgg
     7561 agaaataatg cgagtagtaa tatgcgatga tgagaaagta acttgttcag agatagagaa
     7621 aatgcttagt ttttttgcgt tcgaaaaatg tataaagttg gaagtggacg tgttttttga
     7681 tggagatact ttgacagaat atttgaaaaa agaaaaagct ccagacattc tttttttaga
     7741 tattgaactt ccgggaatga atggggttga ggtcggaaaa tatatcaggg atatattgag
     7801 gaatacagat atgtttatga tatatatatc ttctaaaaag gaatatgctt tagaactgtt
     7861 tcaaaaccag ccatttgatt ttctgataaa accaataaaa aaagaacggc tgtatcatgt
     7921 tatggagaaa atatttagta ttattggaaa aaatgagtgc aattttgagt ataaaaatca
     7981 aggaaatagt tacagaatta tgtacaaaga tattttgtat tttcaaagtg atggaagaaa
     8041 aattaatatt gtaatggaaa agaaaataga aagtttttat ggtaagttat ctgagattga
     8101 acagatgtgt ccagaggggt tgtttttgcg tattcacaaa tcatatttga tcaatatgtg
     8161 ccatgcgaaa gaaattactt ataaatggat aaaaatgata aacggagatg tgttggatat
     8221 tagcagatcg aaccgtgtgg ctataagaag aaaactaatg gagagtatgg caaatgaaat
     8281 tcgtaatgat agctgaactg ttgcttatat tgttttcaaa tggaattcga ttttatgcag
     8341 ttaaaaggta catagatttt tttgctgcca gagaaaaatg tctatggaaa tataattgga
     8401 ttctatatac ttttgcatgt attgggactt atattgttag tattatattt gaatcgccaa
     8461 atttgaatat aatttcgaat gtcattgctt tatttctact ggcatgcccg tataagataa
     8521 agctgtctaa aaaattccta atgacattta ttatatattc tattaattta ctagcagata
     8581 ttatagttgt tcaactgttg gcaggatatg ttcccggaca aagagtaggc tcagcttatc
     8641 aatttataac tagcttggcg attttaattc caactgcttt tttttcagaa tttacaaaga
     8701 aaaaaacgca ggattctcta ccacttatga atgtattcat attgggtatg attcccttgg
     8761 ttagcattgt ttgtatgcac agcattgcaa ctttaacaga aaataacaaa cctgtagttc
     8821 ttacagtagc attcagtttg atactcatca attcattttt gttttattta tattacacat
     8881 taacccaatt ttatgtggcg aaaatgaatg agaagaaact ggagcagata attgatgtat
     8941 atgcacatca gcttgatgtg gtgcaggaat ctcaggagca tattaaaaaa ttgcgtcacg
     9001 atatgaagca tcatttaata gaattatctg ctatggcaca gcaggataag aataaggata
     9061 tgatgagata tttagaacac atggaaaaat ttatgttaaa tccagcagaa aaagtttcga
     9121 cagggaataa agaaattgat ggggttttaa attacatgct caggcgtgcg gatgaattat
     9181 tgaaaattgt gaatctggat attcagattc caaaatcact atacagaaat aattttaata
     9241 tttgtgtgat tttaggaaat ttggtagata atgcggtcag ggaatcgagt aaatctgatg
     9301 aaaagtattt atccattagt gtgcgtgtgc aaaaagatat cctgattatt ttgatagaaa
     9361 atagttatag tggttcaatt gtgcaaaaag gtaatatatt tcaaaccagc caaattgata
     9421 catctattca cgggttaggt ttggaaagtg tgaaacaggt agtagaagca tgtggtggag
     9481 atataaagat tgaatatacg gaaaaacgat tttgggtaca ggttttatta tatttgtcaa
     9541 atattgtaga gaactaaaaa gagccacttg gctctttttt agttccaatt ttgacaaaaa
     9601 aatatacagt ttttgacaat aaaaggcata tgaagagaat ttatggtatg ttataaaaaa
     9661 tatatgttta ggaggatgta acatgaaaaa agatattttg aaattgggta tgaaaatagt
     9721 aaaaaatact gctataaagt tagcagagcg tgatgcaaat acaacatgtc cgtattacgg
     9781 ttatcaggca gaacttccat gtgccgtcaa aaagctgaaa aaaccgtgat tttgtaaatt
     9841 ggttgatttt ttaaagaaaa tatggaagta tatagttcct tttaggaaca ataaaagtaa
     9901 tcaggttgcc atagactata gagttttctt atgaaaacat agtagtttgt ggcaactgtg
     9961 tttttgaaga aaatgaggtt tttaatggaa aagcatagaa aaaaattctc aatacgattg
    10021 atagaaaaaa ttggacatga tgaggaagaa cgagaaatta tccaatatgg attgcatcag
    10081 gggtttctga tattacttaa tttattgaca acagtagttt gtggaatact ctggaaagaa
    10141 ctgccttttg tattattggt attttggggg atattttttt tgagacctta tgctggagga
    10201 tatcatgcag atacagaatt acgttgttat tttctatcga cagcaatgat gaacatggtt
    10261 gtctttttga aaaaaacaat agttttatca aatataatgt ttataataat atggattatt
    10321 actgttatat ttatttggat atatgcccca gtagaaaata ctattcattg tttagacgaa
    10381 gatgcacgca aaaagtatgc gaataataca aagaaaattt tgttatgtaa tggaatcgta
    10441 atgctagtgg gaatatgggt aaaccaaaga attgtcgtag atgcaattat ttggagtcaa
    10501 gtgatgattg cgattgcaat gatagctgga ttatggaaat atagtaccta ataaataatt
    10561 tatataggag aataaagaaa aaagtgtgaa tatacaaaaa ggcattagtc ttgacagaag
    10621 ttccattttt gacacaatta tatacagttt ttggcaaggt gcgttttaag agataattct
    10681 atgctatagt aaattcaaca aacaagttgg tgccaatgtt gtttaataac tgaaaaactt
    10741 ttttagaaag gggaaatgat ttatgagaaa aattattaaa agaacacttt gcgttttaag
    10801 tgcaacaatg tgtgtgctgg ggacagcagc tacagcaagt gcggatacag tttcatttaa
    10861 tgtgacgatt ccgggtgatc catactctta tgcagtaagg aaagcggata cagaacagag
    10921 attctatgta acaggaacat cgtttaataa aagcggtaca ttgagatgca gatctggaaa
    10981 agcaggacag ggaacaagct ccaattcggc gtatatttct tctggttcaa gagcttcctc
    11041 tgccagctac acatcttatg cagcgcctaa ttatacatac gagatgtatg ctaccagtgg
    11101 aacaagtgga ttgaatgtta ggggacgttt cacaccgtaa ataaaactgt agatgaaggc
    11161 ggagaaatac gccttcgttt tttcaaggag gactatatga gaaaaggctt gagacaagca
    11221 atgatagtgc tgggaatatg tatgtgttta gggggctgtg aaaaagaaac ggaggcaaaa
    11281 acagagccgg aaggagagac ggtacagagc gaagacggag atttttttcc ggaatcatat
    11341 tcagaggaaa cagagaaggt gaaatttgag tgtgtagtaa acgttccgga gaaatttgaa
    11401 gttaccaact tccacgcccc tattataaaa ggtgtttcta acattgatgc agaaacagct
    11461 tacaaaaaat atgttgaggg aaaagtagtt acagaagaat atcatgacga accaactatt
    11521 gaaaatgaaa aaggaaatga tacgtatata ttggaggacg gaacagtgat agggttatcg
    11581 ggagtgtttc tgtacaatac acccgaatcc tcaatataca gacaggtagt gagaatgagc
    11641 gaacgcagcg ctccaaaaga taattttaaa tttgcatcag gagacgattg cacagaacag
    11701 gtaaaagaag aattaagatc actgggctgc cctgttgatg aatatcagtt tgactggttc
    11761 tctaccagcg gagaagatta tgcaatattg gagaagcgag ctttagatga cggaatgatt
    11821 gacagtcaaa gggcaaaaca ggacggctgg acagaagcca ataattctta tgagatatat
    11881 gggtggcagc tttatgaggg actgcaggtt cttccgccgt ggataacaag cgcgatgtca
    11941 cgggcgtttg aaagctatca gaaagcgccc atatctgctg tttacacaaa acagggtatg
    12001 ttgagtctgg cactgacaga agcgccatgt atatttgaac attctgatga aaccctggag
    12061 tttctgaagt tccctgaaat tgcagatata ctggaagaaa aatacagtgc tttattagac
    12121 gatgccgttt atacggtgac ttatgcaaaa ttagtcctgc ggacttattt tgatgagggt
    12181 cagaaattag cggcagagcc ggtctggtat tttgaagtaa cagacggtac ttctatggag
    12241 gttgctttgc ttaatgcggt tacaggaact gaaattttcc tgaattagca acgcttgtca
    12301 taccagattt tgcctgagaa agagagtgtg ataattttgc agtgttttat aaattacctt
    12361 cggacagatt ttcgccggct tggaaaaagt tatcgatggc tggctggaat tgttggtgta
    12421 gtggcaatcc tgtttttttc tctggaaagc gtgttgtttc aaaaagggct tgaaaatgga
    12481 aacgtactgt ctacctatgt gtattctaca aatatgacag gatttctgat tgcatattct
    12541 ttctgcgctt ttccatttgc aggggtatat ccggaagaac aggagcataa gtatattcgt
    12601 tacaatgtga taagaggaag cttaaagtca tatgtactat ctaaaacaac cgttatctat
    12661 atcagttcac tgagcattat gatattggga tcagttttgt ttctgttttt gtgccgtaca
    12721 tatgttccgt ggacagactg gagtatagat tcgtatggaa tagaattaaa cggctgttat
    12781 ggaagcattc tggaagaggg acatgtaatt ttatactgta cgctgtacgc attgaatctg
    12841 gggcttattg cgggggcatt gtcgaatatg gctgccttat gttctgtgtt tatatcaaat
    12901 actgtgctgg ttcttgtctt tccggtactg gcatttcgcg ttctggtatc tgtgaatata
    12961 gctgattaca atatctacgc tttttatgcg tatacgaaaa tatttgcaag tgacggagta
    13021 aaccttttgt ttctgacggt tatatcagtg ggcatttccg ctctatcagc cgcggggtgc
    13081 tattgggggc tgaaaaagaa aatgtagcgg agggaggact atatgaaaac attaaaatac
    13141 ataatgaaaa cttctgcgca aaaaatattt aatgttaaat ttgcgacttt ctgcgcggcg
    13201 tttttaatct tgtcgtggac gtatgatcag ccatatttac agtttgttaa ggaaaaaaat
    13261 tatccgattt catggtgcat ttttcctttt tatatgtcct catttggaat tttatctatt
    13321 ttttatgtag gaattgttta tattcattct gatgttccat ttatgcagca tattaatatg
    13381 tatcaggtaa tccgtaccgg gagggaacgc tgggcactca gccagattgc cggtatcctg
    13441 ataaggtctt tttttgcagt tatcctgtct gcaatcgcag ctgttcttcc gttttgggga
    13501 catatagaat tttcgacaga ctggggaaaa gttataaaaa cgctcgcttc gcaaagagca
    13561 gatgagggat ttggatttgg aatggggcaa atgcttgatt ttcgcttcca ttatgggatt
    13621 cttgggaaat ttacgccggt acagcttatg ataattactg tcctgatatg tacattgata
    13681 tgtacgtttc ttggcatttt gatgtttctt atcagtttgt atgccggtaa aatccttgca
    13741 gtcgcagtga caatgatgag tgtggttgca ttatttattg tggagaatat atatggggaa
    13801 tggaaactga ttgtggcgca tgttgtacct acatactggg cggaggtggc attaagcgcg
    13861 acgcctgtca gcggacgtta tcgaatccct tccctgacat atatttttac atttttaatt
    13921 gttgcggttg ttttcatgtc tgtgataatt ttctgtaaag taaaacatac agagtttcac
    13981 tgggaaaatg aggacgcgta gcttacagac aggaggacag gacagatgga aaaacagagg
    14041 attgaagtaa atcatgtatt taaaagcttt aaggaaaaag aagtgttaaa agatgtatcg
    14101 ctgacctgtg aaagcggaaa aatatacgga atcgtaggac ataacgggtc tggcaaaacc
    14161 gtacttttca aatgtatctg cggatttttt tactgtgaca gaggagaaat cagagtaaat
    14221 gggaaatgta tggggaaaga tgccgacatg ctgcagaatg ccggaattat tatagaagaa
    14281 ccgggttttt tgcgccagtg gagcgggttt cataatctgg aatttctgta tacaatccga
    14341 aataaactga ataaaaaata catgtattcc gttctggaaa aggtgggact tgaaccacgt
    14401 tcaaaaattc ctgtaggaaa atattctctt ggtatgcggc agcgtttagc aatcggtcag
    14461 gcgattatgg aaaatccaga tattttaata ctggatgaac ctatgaacgg tttagataaa
    14521 aatggggtac aggaaatgag gggactgttt gagcagatga aaaacgaggg aaaactgatt
    14581 atcctggcaa gccataatag agaggatatt gatgtgttgt gtgatgaagt atatgaaatg
    14641 gaaaatggta tattgaaaaa acgaagataa ttaaaagata tagttggagg ttagtatgat
    14701 aataccatat gaaattttta aggaaaacaa aagatttaaa gaaagtatag ataatgccca
    14761 gaatgagaca gatatattgt tgtataatgc ggctaaagaa tatagtaata gtgtgaggaa
    14821 aagggcaaaa gcggtaacgg atataatcat ggaacgaatt gaaaaagaga tcaagaacag
    14881 ttaaacaaaa taagtggcat ctgtcaaaat gataccatta tatatccttg cgggtcattt
    14941 ttccggacat caatggtgtc agggaaagag ctgagtaatc atcttccgta aaagctggta
    15001 gtgtaaaata gtttgtgttt ttggtaaaaa ataactcctt tttggtaaga atttagatat
    15061 gacaattctt atcgaaaagg agtatttttt atggcagttg caaaagaaca aattcgacag
    15121 atcatctcag aaaacaacat taatagcgtt gcagatatat acacgcttct gaaagacagt
    15181 ttcaaggata tcctgcagga gctgatggag gcagaactgg atgcaactcc tggctacgag
    15241 aaaaaccata agggagatct acagacagac aataaaagaa atggtcattc tacaaaaaac
    15301 ttaaagagtc aatacggtga atttcaaatc gatgtaccaa gagaccgtaa cggtgagttt
    15361 gaaccaaaac tcatccctaa ataccagaga gatatttccg ggattgagga aaaagtgatc
    15421 tctttatatg cccgtggtat gagtacacgt gacatccacg accagctcca ggatctttat
    15481 ggaattgagc tatcagctga aatggtcagc aagatcacag acaagatact tcctcaggtt
    15541 aaggaatggc agtcccgtcc tctgaacccg gtttatccgt ttgtctttat ggactgtatt
    15601 cattataaag tacgtgagga tggcagaatc ctgagtcgtg ctgcgtatgt agttcctggc
    15661 gttacagtgg agggatacaa agatatcctc agcatcacag caggcgcaaa tgaaaccagc
    15721 aagttctggc ttgggatgct taatgatctt aagaaccgcg gagtaaaaga tgtccttttc
    15781 ttctgcgtgg atggtcttcc gagttttaaa gaagctattc aggcagttta tccgcaggca
    15841 gagatccaga gatgtgtgat ccatatgcta cgcaattctt tcaaatatgt aaattataat
    15901 gatctgaaaa agttttcctc ggatttcaaa gaagtgtaca atgctccgaa cgaaacagcc
    15961 gctttaacag agctggagaa catgaaagaa aaatggggga agaaatatcc gtacgcgatc
    16021 agtaactggg aaaataattg ggaagatgta agttcctttt tccagttttc taatgatatc
    16081 agacgcatta tgtacacgac aaatatcata gaaggattga accgccagta tcggaaagtc
    16141 acgaaaacga aaagcgtatt cccaagcgat cctgcattgg aaaagatgct gtatcttgcc
    16201 agcgagaacg tagtcaaaaa gtggacgcag agataccgga actgggatca ggtattgaat
    16261 cagctgatag tcctttacgg agaacggctc actgcttatc tgtaagagaa aagaaaagca
    16321 ggaatgggga agctctttta agcccctcat tcctgctctc tgtctattcc ttcggcattt
    16381 atattattgc cagaaatttc cgatcctatt ccagaggtcg ggtgtgggca gagcccacaa
    16441 aaggcaatga tcatgatgcc ttacttgtca tgcaaaaaaa tcgaaaatga tgtatataat
    16501 tttcctacat ggcaatactg taagtacaaa gatatattcg acagccgcat aatcattaat
    16561 tcgacagcaa aattttacat atctatttct tatcagaaag atttactttc catagacaca
    16621 agaattttta caccctctaa aagcttcacc gttatcctgc ttctgcttta atttccggaa
    16681 tacttcatct gcattcttat ctttcagata aatcggttag gtactcccct atttgttaag
    16741 tatagtcctc attcgtgcct tgaaaatgtc ttcggctgtt cttttgtctt ttatcatttg
    16801 taaggattta cgtttgtcct cctttatatg ctcattttac cagaatatac ttcatttctc
    16861 cagtcgaaat tgtgaaaaga caggttgact tttcgacagt gtattattta ctctggaaaa
    16921 agaaaattat ttttattaaa attgcaactt taccattcaa aatccgtctt atcttatgaa
    16981 ggcaaataaa agaaacgtga ggtgaaaaaa gtggaagata cagtaattat caatctgtat
    17041 tttgacagat cagaaaaagc catacaggcg accgaagaaa aatatagcag gtactgtttt
    17101 agtattgctt ggaatgttct gtatgataaa gaagactcca atgaatgtgt caatgataca
    17161 tggctagcca catggaactc cataccaccc agaaaaccgg caattctgtc tgcttttctt
    17221 ggaaaaataa cccgaaacct ggcaattgac tgttttcgca ggaaaaaagc tgcaaaacgg
    17281 tcaacagagc acatattaga attatgcaaa gaactggaag agatagagga tgtaacagca
    17341 tattctttga atgatgaaat ccagagaaaa gagattctgg aaatccttga aaaatttctg
    17401 gaatccctga aaaaaggtga ttgtgacatt tttatacgac gctactggta tatggacagc
    17461 atcagtgaaa tttcagcccg gcatggaatt tcggaaagca gaatcaaatc cagtctctat
    17521 cgaagcagaa agaaactatg ggaaagggtg aaacatttat atggaaaaag gatttaagac
    17581 attagaactg atcggtgatc tggatgataa atacatatat gaagcttcta aaccatggaa
    17641 aaaacagcat cgttttttcc atatacaaag gagttggaaa acagcagtcg ccgggatcat
    17701 attgcttatt atggttggat gcacattaag atatcaggaa gatgtaaaag cagcattaca
    17761 gagagtaact tcatggatcg gacaggcatt gggaattaag aacggtgata ccgattctta
    17821 tacaaatgtt gtaggaaaaa gcatttcaag agatggaatc accataacat taaatgagat
    17881 tgtgatggac agcaaaaatt tatggattgc gtattacgac agcgaagatt cagacgcaga
    17941 tatgaaggat gcggtggaag acaaactttt atatacagaa gtatgcatta acggtcagga
    18001 aattcagcag ggcttaggcc aaagaacagt taatgctttc tcagaaaatc caataacagt
    18061 ggaagatttc acaatcggag aagaagttaa cactgaggga actgtaaaca tagagttcaa
    18121 agtctggccg attgcaatgg acgatgctga tacatgggaa aatgttcaga aaatacaggc
    18181 tgatacagaa ccttatacat ttaaacttgc gacatcaaaa gaagagctgg agaaaaacac
    18241 tgtggattta aatctgaatc agaatattaa aatggattcc aatgtcctga acctcacaga
    18301 attcagatgg aatccattcg aaagtacaat ttacggaatg tatcatggaa cagtatatat
    18361 tgacagtgat tattatctga ttggaacaga cgatcaggga aacaaaatct gctatcagga
    18421 aacaggaaga aatggtcagg aaactatgtt ccggcaaacg ataggtctat atcccggata
    18481 tgaagaaatc tccccggaag caaacacaat cacattacag ttatatgaag taaaaaacga
    18541 cacagcgcat caggtgtctg aagaaaaaat ggataaggat ccctctgatg atatctacga
    18601 agaatccaca gtctatgtat ataatgaggg agaaagcccc acagatgatg caataccaat
    18661 aggagacaag tttacagtac agataagatg aaaatgaaga agacatatta tttaaacaaa
    18721 gatgttctgc cgacaatccc ggtaccacat gattgtataa ttaaaaaaat ccgtatagag
    18781 cacaaatggc taatatttac ctttgacaat gatacatcct attatgattc tgtcagaaaa
    18841 cttagcccaa acatcaggaa tttgattttg aaatatcatc taagtaatcc agaagacttt
    18901 tctgtatata agtgtagtaa aactttaaaa cgaatcttaa ataaagaatg ctatatacgc
    18961 cagaatacca ggaaaattac aaaattaccc cgcaaacgtc tggaatattt gtaccataat
    19021 gtaggatact gttcgattat aactaagttg cattcagatg ctcctgttat gatagatgca
    19081 ggggttgatt atctggtata tgagtggata gaatagtatg actaatgaag taaaatatat
    19141 atctttgtag acgttacatc ctcgaaacgt tatactattt ccataaacta atcgaggtga
    19201 tcccaaaatg aaaaacaaaa tcctggtaat cgaagatgac agagcaattt ccgaattatt
    19261 atgtatgaac ctaaccatag ctggatacga aacagtagcc gcctacgacg gaatagaagc
    19321 ccagcgccta ttgctatgga atgaagatgc agaccttgca gttgtcgata ttatgcttcc
    19381 cggcaaagat ggctttgctc tgatggaaga tttccgcgca aagaatctcc cggtgatcta
    19441 ccttactgca aaagatgacg tagcatccaa agtaaaaggc ctgaaactcg gtgcagaaga
    19501 ttatatggta aagcctttcg aaatgttgga acttcttgta cggattgaaa aaatccttga
    19561 aagaaccggc cgtgcaaaga gaattctcac aatcaaaaat attcaggcag atctccagag
    19621 ccatcagatt ctgaaagatg ggattcccgt aaacctgaaa ccactggaat acgatctctt
    19681 tatcctgctc ttacagaaca aaaacatcgc acttggaaga gaagaactat taaaacgtgt
    19741 ctggggcgaa gaatatctgg gagagagcag aactgtagac gtgcatatcg gccagctccg
    19801 caagaaactg gagttgtacg atgaaataaa aacaatccca aaacttggct atcgactgga
    19861 ggactaa
//
