GCF_030026565.1_ASM3002656v1_genomic - 6 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

c00001_NZ_JASE.. (original name was: NZ_JASERB010000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	thiopeptide	88,416	114,710	O-antigen	Saccharide	14%

c00009_NZ_JASE.. (original name was: NZ_JASERB010000017.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 9.1	siderophore	46,536	60,966	aerobactin	Other	77%

c00016_NZ_JASE.. (original name was: NZ_JASERB010000003.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	redox-cofactor	162,648	184,810	lankacidin C	NRP + Polyketide	13%

c00018_NZ_JASE.. (original name was: NZ_JASERB010000005.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 18.1	arylpolyene	26,756	70,352	aryl polyenes	Other	100%

c00020_NZ_JASE.. (original name was: NZ_JASERB010000007.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 20.1	NRPS	131,031	174,945	thailanstatin A	NRP + Polyketide	10%

c00022_NZ_JASE.. (original name was: NZ_JASERB010000009.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	terpene	247,914	271,528	carotenoid	Terpene	100%

No secondary metabolite regions were found in these records:: c00002_NZ_JASE.. (original name was: NZ_JASERB010000010.1); c00003_NZ_JASE.. (original name was: NZ_JASERB010000011.1); c00004_NZ_JASE.. (original name was: NZ_JASERB010000012.1); c00005_NZ_JASE.. (original name was: NZ_JASERB010000013.1); c00006_NZ_JASE.. (original name was: NZ_JASERB010000014.1); c00007_NZ_JASE.. (original name was: NZ_JASERB010000015.1); c00008_NZ_JASE.. (original name was: NZ_JASERB010000016.1); c00010_NZ_JASE.. (original name was: NZ_JASERB010000018.1); c00011_NZ_JASE.. (original name was: NZ_JASERB010000019.1); c00012_NZ_JASE.. (original name was: NZ_JASERB010000002.1); c00013_NZ_JASE.. (original name was: NZ_JASERB010000020.1); c00014_NZ_JASE.. (original name was: NZ_JASERB010000021.1); c00015_NZ_JASE.. (original name was: NZ_JASERB010000022.1); c00017_NZ_JASE.. (original name was: NZ_JASERB010000004.1); c00019_NZ_JASE.. (original name was: NZ_JASERB010000006.1); c00021_NZ_JASE.. (original name was: NZ_JASERB010000008.1)

Compact view

c00001_NZ_JASE.. - Region 1 - thiopeptide

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Location: 88,416 - 114,710 nt. (total: 26,295 nt) Show pHMM detection rules used

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

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Thiopeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.24	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.16	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0001534.1	0.14	Other	branched-chain fatty acids	Streptomyces filamentosus
BGC0000800.1	0.14	Saccharide	xanthan	Xanthomonas campestris
BGC0001285.1	0.07	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0001302.1	0.06	Other	lomofungin	Streptomyces lomondensis
BGC0002012.1	0.05	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001283.1	0.05	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0001196.1	0.04	NRP	desotamide	Streptomyces scopuliridis
BGC0001814.1	0.04	NRP	ulleungmycin	Streptomyces sp. KCB13F003

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.58	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.47	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0001534.1	0.44	Other	branched-chain fatty acids	Streptomyces filamentosus
BGC0000800.1	0.44	Saccharide	xanthan	Xanthomonas campestris
BGC0001285.1	0.29	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0001302.1	0.24	Other	lomofungin	Streptomyces lomondensis
BGC0002012.1	0.23	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001283.1	0.22	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0001196.1	0.20	NRP	desotamide	Streptomyces scopuliridis
BGC0001814.1	0.17	NRP	ulleungmycin	Streptomyces sp. KCB13F003

Similar known gene clusters

Thiopeptide predictions

No core peptides found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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Thiopeptides

Core peptide predictions

No core peptides found.

c00009_NZ_JASE.. - Region 1 - siderophore

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Location: 46,536 - 60,966 nt. (total: 14,431 nt) Show pHMM detection rules used

siderophore: IucA_IucC

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KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001499.1	0.56	Other	aerobactin	Pantoea ananatis
BGC0001498.1	0.40	Other	aerobactin	Xenorhabdus szentirmaii DSM 16338
BGC0001453.1	0.29	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.29	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001572.1	0.29	Other	desferrioxamine E	Pantoea agglomerans
BGC0001531.1	0.29	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0001713.1	0.28	Other	ochrobactin	Ochrobactrum anthropi
BGC0001478.1	0.28	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0001555.1	0.27	RiPP	colicin V	Escherichia coli chi7122
BGC0000939.1	0.26	Other	aerobactin	Grimontia hollisae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001499.1	0.82	Other	aerobactin	Pantoea ananatis
BGC0001498.1	0.72	Other	aerobactin	Xenorhabdus szentirmaii DSM 16338
BGC0001453.1	0.63	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.63	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001572.1	0.63	Other	desferrioxamine E	Pantoea agglomerans
BGC0001531.1	0.62	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0001713.1	0.62	Other	ochrobactin	Ochrobactrum anthropi
BGC0001478.1	0.62	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0001555.1	0.61	RiPP	colicin V	Escherichia coli chi7122
BGC0000939.1	0.59	Other	aerobactin	Grimontia hollisae

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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c00016_NZ_JASE.. - Region 1 - redox-cofactor

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Location: 162,648 - 184,810 nt. (total: 22,163 nt) Show pHMM detection rules used

redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001540.1	0.16	Other	CC-1065	Streptomyces zelensis
BGC0000678.1	0.14	Terpene	pentalenolactone	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000847.1	0.14	Other (Non-NRP beta-lactam)	thienamycin	Streptomyces cattleya
BGC0001995.1	0.11	Terpene	heptelidic acid	Aspergillus oryzae RIB40
BGC0001100.1	0.09	NRP, Polyketide	lankacidin C	Streptomyces rochei
BGC0001902.1	0.09	NRP, Polyketide	bengamide	Myxococcus virescens
BGC0000653.1	0.08	Terpene	pentalenolactone	Streptomyces arenae
BGC0001626.1	0.08	Polyketide	isoindolinone	Stachybotrys chlorohalonata IBT 40285
BGC0001365.1	0.08	NRP	clapurines	Claviceps purpurea 20.1
BGC0000321.1	0.07	NRP	chaetocin	Collariella virescens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001540.1	0.47	Other	CC-1065	Streptomyces zelensis
BGC0000678.1	0.43	Terpene	pentalenolactone	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000847.1	0.43	Other (Non-NRP beta-lactam)	thienamycin	Streptomyces cattleya
BGC0001995.1	0.38	Terpene	heptelidic acid	Aspergillus oryzae RIB40
BGC0001100.1	0.34	NRP, Polyketide	lankacidin C	Streptomyces rochei
BGC0001902.1	0.33	NRP, Polyketide	bengamide	Myxococcus virescens
BGC0000653.1	0.32	Terpene	pentalenolactone	Streptomyces arenae
BGC0001626.1	0.31	Polyketide	isoindolinone	Stachybotrys chlorohalonata IBT 40285
BGC0001365.1	0.31	NRP	clapurines	Claviceps purpurea 20.1
BGC0000321.1	0.29	NRP	chaetocin	Collariella virescens

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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c00018_NZ_JASE.. - Region 1 - arylpolyene

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Location: 26,756 - 70,352 nt. (total: 43,597 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

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core biosynthetic genes

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Gene details

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KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.55	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.53	Other	APE Ec	Escherichia coli CFT073
BGC0000837.1	0.26	Other	APE Vf	Aliivibrio fischeri ES114
BGC0000228.1	0.26	Polyketide	granaticin	Streptomyces violaceoruber
BGC0001197.1	0.22	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000194.1	0.22	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0000219.1	0.22	Polyketide, Saccharide	elloramycin	Streptomyces olivaceus
BGC0001897.1	0.21	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000272.1	0.21	Polyketide	spore pigment	Streptomyces collinus
BGC0000261.1	0.21	Polyketide	R1128	Streptomyces sp. R1128

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.82	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.80	Other	APE Ec	Escherichia coli CFT073
BGC0000837.1	0.60	Other	APE Vf	Aliivibrio fischeri ES114
BGC0000228.1	0.60	Polyketide	granaticin	Streptomyces violaceoruber
BGC0001197.1	0.56	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000194.1	0.55	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0000219.1	0.54	Polyketide, Saccharide	elloramycin	Streptomyces olivaceus
BGC0001897.1	0.54	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000272.1	0.54	Polyketide	spore pigment	Streptomyces collinus
BGC0000261.1	0.53	Polyketide	R1128	Streptomyces sp. R1128

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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c00020_NZ_JASE.. - Region 1 - NRPS

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Location: 131,031 - 174,945 nt. (total: 43,915 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.32	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001890.1	0.28	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0001437.1	0.25	NRP	obafluorin	Pseudomonas fluorescens
BGC0001710.1	0.25	NRP	obafluorin	Pseudomonas fluorescens
BGC0001132.1	0.24	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000417.1	0.24	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0001131.1	0.24	NRP	ambactin	Xenorhabdus miraniensis
BGC0001844.1	0.23	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758.1	0.23	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.66	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001890.1	0.61	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0001437.1	0.58	NRP	obafluorin	Pseudomonas fluorescens
BGC0001710.1	0.58	NRP	obafluorin	Pseudomonas fluorescens
BGC0001132.1	0.58	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.58	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000417.1	0.57	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0001131.1	0.57	NRP	ambactin	Xenorhabdus miraniensis
BGC0001844.1	0.57	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758.1	0.56	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 131030 - 174945:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg20_140

Search NORINE for peptide: strict or relaxed

AMP-binding (472..873): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

c00022_NZ_JASE.. - Region 1 - terpene

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Location: 247,914 - 271,528 nt. (total: 23,615 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

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Gene details

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KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000642.1	0.58	Terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000640.1	0.55	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000656.1	0.54	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000638.1	0.53	Terpene	carotenoid	Pantoea ananatis
BGC0000641.1	0.53	Terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0000647.1	0.48	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000639.1	0.45	Terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000630.1	0.36	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000648.1	0.34	Terpene	carotenoid	Myxococcus xanthus
BGC0000664.1	0.26	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000642.1	0.83	Terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000640.1	0.81	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000656.1	0.81	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000638.1	0.80	Terpene	carotenoid	Pantoea ananatis
BGC0000641.1	0.80	Terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0000647.1	0.77	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000639.1	0.75	Terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000630.1	0.68	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000648.1	0.67	Terpene	carotenoid	Myxococcus xanthus
BGC0000664.1	0.59	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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