LOCUS       c00016_NZ_JAHH..       10387 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAHHXM010000024.1 Oceanobacillus caeni strain 179-K 2A2 HS
            NODE_24_length_51614_cov_150.498729, whole genome shotgun sequence.
ACCESSION   c00016_NZ_JAHH..
VERSION     c00016_NZ_JAHH..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:07:09
            Original ID  :: NZ_JAHHXM010000024.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 18098
            Orig. end    :: 28485
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10387
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[23098:23485](-)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5387)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     cand_cluster    1..10387
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10387
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="1"
                     /rules="ectoine_synt"
                     /tool="antismash"
     CDS             834..1676
                     /locus_tag="ctg16_19"
                     /transl_table=11
                     /translation="VDFTELADYIIINLYKKGVFHMDYNIIEEIVTKIYQARETKTPIE
                     FIRNDYTLDENTAYAVQDELMKRIQEVHNEEIIGYKISMTSKETQAIANTHEPAYGTLL
                     TSNIVESGNNISLSNLFAPLVEPELVFILTEDLSPTATEEEILNKSKIAAGLEIPDSRY
                     IDWFPNFSLADLLSDDTATGLVVVSEGVTPPSLDELANIKMELFHNGEKISEGVSSAVL
                     DNPVSAVAWLVKKLASHHKTLKKGMMISSGTFISPLPVQVGKYEASYSSIGKLEVTFS"
     CDS             complement(2055..2489)
                     /locus_tag="ctg16_20"
                     /transl_table=11
                     /translation="MTQLRNMMTQNVMTVNESQSVQEAAAIMSQYNIGAVPVVNSGGQM
                     VGIVTDRDITLRTTAQGQNAQTPVSEVMTAQQMVKGTPDMDADQAAELMSQQQIRRLPI
                     EENGQLVGMVALGDLAVQNQHADEAGQALASISTPSSPQQ"
     PFAM_domain     complement(2130..2285)
                     /aSDomain="CBS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00571.30"
                     /description="CBS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg16_20_0002"
                     /evalue="2.30E-06"
                     /label="ctg16_20"
                     /locus_tag="ctg16_20"
                     /protein_end="120"
                     /protein_start="68"
                     /score="28.0"
                     /tool="antismash"
                     /translation="VSEVMTAQQMVKGTPDMDADQAAELMSQQQIRRLPIEENGQLVGM
                     VALGDLA"
     PFAM_domain     complement(2328..2474)
                     /aSDomain="CBS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00571.30"
                     /description="CBS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg16_20_0001"
                     /evalue="8.20E-14"
                     /label="ctg16_20"
                     /locus_tag="ctg16_20"
                     /protein_end="54"
                     /protein_start="5"
                     /score="51.9"
                     /tool="antismash"
                     /translation="NMMTQNVMTVNESQSVQEAAAIMSQYNIGAVPVVNSGGQMVGIVT
                     DRDI"
     CDS             2751..4007
                     /locus_tag="ctg16_21"
                     /transl_table=11
                     /translation="MMDYSPYPRNDVLCIDMRSFYASVEAIKLGLDPMTTLLAVVGDPN
                     RSGSIVLAASPTLKKKYSISNVSRYFELPKDPDIHIVPAHMADYLHVSIEITKLINQYV
                     PKEAIHQYSVDEVWVTVNGLKKLFGDRWEVAKKIKQDIFDHFGITSSIGIGDNKFLAKV
                     VMDIHGKKSGIAECKYEDVEEKLWPFPVEEIWGIGSRMKRNLNRMGIVTLGQLANYSLD
                     HLKSRFGIMGEQLYFHAWGIDLSPVYGNFTKTEQKGFGHGIALLRDYTKEEISTCILDL
                     CEEVCRRARTADKVGKTIHLGISYSKDTGGGGFSRSKSIEIPTNVTMDVHHVCMQLFHQ
                     FYDGFSNIRHVYVTLDNLSNKAETQLDLFEDRSKKTDIGYVMDAIRDKYGSTAILRASS
                     YTAAGVTLERSKKIGGHFA"
     PFAM_domain     2793..3245
                     /aSDomain="IMS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00817.22"
                     /description="impB/mucB/samB family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg16_21_0003"
                     /evalue="2.30E-28"
                     /label="ctg16_21"
                     /locus_tag="ctg16_21"
                     /protein_end="165"
                     /protein_start="14"
                     /score="99.2"
                     /tool="antismash"
                     /translation="IDMRSFYASVEAIKLGLDPMTTLLAVVGDPNRSGSIVLAASPTLK
                     KKYSISNVSRYFELPKDPDIHIVPAHMADYLHVSIEITKLINQYVPKEAIHQYSVDEVW
                     VTVNGLKKLFGDRWEVAKKIKQDIFDHFGITSSIGIGDNKFLAKVVM"
     PFAM_domain     3285..3380
                     /aSDomain="IMS_HHH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11798.10"
                     /description="IMS family HHH motif"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg16_21_0004"
                     /evalue="2.10E-08"
                     /label="ctg16_21"
                     /locus_tag="ctg16_21"
                     /protein_end="210"
                     /protein_start="178"
                     /score="34.1"
                     /tool="antismash"
                     /translation="YEDVEEKLWPFPVEEIWGIGSRMKRNLNRMGI"
     PFAM_domain     3528..3854
                     /aSDomain="IMS_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11799.10"
                     /description="impB/mucB/samB family C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg16_21_0005"
                     /evalue="3.00E-15"
                     /label="ctg16_21"
                     /locus_tag="ctg16_21"
                     /protein_end="368"
                     /protein_start="259"
                     /score="56.7"
                     /tool="antismash"
                     /translation="GHGIALLRDYTKEEISTCILDLCEEVCRRARTADKVGKTIHLGIS
                     YSKDTGGGGFSRSKSIEIPTNVTMDVHHVCMQLFHQFYDGFSNIRHVYVTLDNLSNKAE
                     TQLDL"
     CDS             4169..4594
                     /locus_tag="ctg16_22"
                     /transl_table=11
                     /translation="MYELKTKENDNSVIEFIEQVENSKKREDAYRLLDIFTETTGYKAK
                     MWGTSIIGFGSYHYKYATGHEGDAPLVGFSPRKTNFSLYFATGDTERDMLLQEFGKHKA
                     GKSCVYINKIADIDVEVLKKLIQQSIRFLREMYPDTK"
     PFAM_domain     4241..4555
                     /aSDomain="DUF1801"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08818.13"
                     /description="Domain of unknown function (DU1801)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg16_22_0006"
                     /evalue="1.80E-14"
                     /label="ctg16_22"
                     /locus_tag="ctg16_22"
                     /protein_end="129"
                     /protein_start="24"
                     /score="54.1"
                     /tool="antismash"
                     /translation="KREDAYRLLDIFTETTGYKAKMWGTSIIGFGSYHYKYATGHEGDA
                     PLVGFSPRKTNFSLYFATGDTERDMLLQEFGKHKAGKSCVYINKIADIDVEVLKKLIQQ
                     S"
     CDS             4711..4956
                     /locus_tag="ctg16_23"
                     /transl_table=11
                     /translation="MGFIIIEVCDYNILSSEELEEVFNRPEVAVMSYECMNYCGMCAMR
                     PYAMVNGKRVFGKTTEECIEKIKKEVEKELEELENF"
     PFAM_domain     4720..4929
                     /aSDomain="DUF1450"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07293.13"
                     /description="Protein of unknown function (DUF1450)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg16_23_0007"
                     /evalue="1.40E-22"
                     /label="ctg16_23"
                     /locus_tag="ctg16_23"
                     /protein_end="73"
                     /protein_start="3"
                     /score="79.3"
                     /tool="antismash"
                     /translation="IIIEVCDYNILSSEELEEVFNRPEVAVMSYECMNYCGMCAMRPYA
                     MVNGKRVFGKTTEECIEKIKKEVEK"
     CDS             complement(5001..5387)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_24"
                     /sec_met_domain="ectoine_synt (E-value: 6.5e-51, bitscore:
                     163.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVKSLEDIMGTEAETKGETWASRRFVLKKDGVGFSMTNTVIEAG
                     TENYFWYKNHIEAVYLIEGEGEIEKVETGEVWQLKPHTMYLLDQNDKHIVRVRKRMQMI
                     CVFNPPLVGTETHNEEGYYPLLTE"
     PFAM_domain     complement(5013..5387)
                     /aSDomain="Ectoine_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06339.14"
                     /description="Ectoine synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg16_24_0008"
                     /evalue="1.60E-56"
                     /label="ctg16_24"
                     /locus_tag="ctg16_24"
                     /protein_end="125"
                     /protein_start="0"
                     /score="190.0"
                     /tool="antismash"
                     /translation="MIVKSLEDIMGTEAETKGETWASRRFVLKKDGVGFSMTNTVIEAG
                     TENYFWYKNHIEAVYLIEGEGEIEKVETGEVWQLKPHTMYLLDQNDKHIVRVRKRMQMI
                     CVFNPPLVGTETHNEEGYYPL"
     CDS             complement(5436..6860)
                     /NRPS_PKS="Domain: Aminotran_3 (80-414). E-value: 6.4e-79.
                     Score: 257.2. Matches aSDomain:
                     nrpspksdomains_ctg16_25_Aminotran_3.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 380; E-value:
                     2.2e-115)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_25"
                     /sec_met_domain="Aminotran_3 (E-value: 3.6e-81, bitscore:
                     264.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLIREQTLLHAGKVVFFSKERKSKPTRNIDVSFSPDFLNNLEKD
                     EIMIMTTAVINNNKMETFEKLESAVRSYSRGWPTVFEKSKGYKLWDVDGKEYIDFFAGA
                     GTLNYGHNDTKMQEKIIEYIQQDGILHSLDMGTTPRKEFLETFQEIILTPRNLDYKVMF
                     PGPTGTNSVESALKIARKVTGRDTVISFTNAFHGMTIGSLSVTGNSFKRHGAGVPLHHT
                     VSMPFDDYVEDQNSIAYIERFLEDSGSGVALPAAIILETVQGEGGINAARMDWLKKIER
                     ICRRWDILLIVDDIQAGCGRTGTFFSFEPAGIKPDIVCLSKSIGGVGLPMALTLIKPEY
                     DKWGPGEHNGTFRGNNLAFIAAKEALRFWETDQFSSEIQDKAKLYKVKIDKIIAKYPEL
                     NGEARGRGLMQGIAVHVDDLASKICTKAFERGLILETSGPNDEVVKFLPPLIIDEEGIM
                     KGMAILDDSIAQVLSS"
     aSDomain        complement(5445..6689)
                     /aSDomain="TIGR00709"
                     /aSTool="tigrfam"
                     /description="dat: 2,4-diaminobutyrate 4-transaminase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg16_25_0002"
                     /evalue="1.50E-163"
                     /identifier="TIGR00709"
                     /label="ctg16_25"
                     /locus_tag="ctg16_25"
                     /protein_end="472"
                     /protein_start="57"
                     /score="542.4"
                     /tool="antismash"
                     /translation="NKMETFEKLESAVRSYSRGWPTVFEKSKGYKLWDVDGKEYIDFFA
                     GAGTLNYGHNDTKMQEKIIEYIQQDGILHSLDMGTTPRKEFLETFQEIILTPRNLDYKV
                     MFPGPTGTNSVESALKIARKVTGRDTVISFTNAFHGMTIGSLSVTGNSFKRHGAGVPLH
                     HTVSMPFDDYVEDQNSIAYIERFLEDSGSGVALPAAIILETVQGEGGINAARMDWLKKI
                     ERICRRWDILLIVDDIQAGCGRTGTFFSFEPAGIKPDIVCLSKSIGGVGLPMALTLIKP
                     EYDKWGPGEHNGTFRGNNLAFIAAKEALRFWETDQFSSEIQDKAKLYKVKIDKIIAKYP
                     ELNGEARGRGLMQGIAVHVDDLASKICTKAFERGLILETSGPNDEVVKFLPPLIIDEEG
                     IMKGMAILDDSIAQVL"
     aSDomain        complement(5454..6677)
                     /aSDomain="TIGR02407"
                     /aSTool="tigrfam"
                     /description="ectoine_ectB: diaminobutyrate--2-oxoglutarate
                     aminotransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg16_25_0001"
                     /evalue="4.00E-209"
                     /identifier="TIGR02407"
                     /label="ctg16_25"
                     /locus_tag="ctg16_25"
                     /protein_end="469"
                     /protein_start="61"
                     /score="692.3"
                     /tool="antismash"
                     /translation="TFEKLESAVRSYSRGWPTVFEKSKGYKLWDVDGKEYIDFFAGAGT
                     LNYGHNDTKMQEKIIEYIQQDGILHSLDMGTTPRKEFLETFQEIILTPRNLDYKVMFPG
                     PTGTNSVESALKIARKVTGRDTVISFTNAFHGMTIGSLSVTGNSFKRHGAGVPLHHTVS
                     MPFDDYVEDQNSIAYIERFLEDSGSGVALPAAIILETVQGEGGINAARMDWLKKIERIC
                     RRWDILLIVDDIQAGCGRTGTFFSFEPAGIKPDIVCLSKSIGGVGLPMALTLIKPEYDK
                     WGPGEHNGTFRGNNLAFIAAKEALRFWETDQFSSEIQDKAKLYKVKIDKIIAKYPELNG
                     EARGRGLMQGIAVHVDDLASKICTKAFERGLILETSGPNDEVVKFLPPLIIDEEGIMKG
                     MAILDDSIA"
     PFAM_domain     complement(5463..6626)
                     /aSDomain="Aminotran_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00202.23"
                     /description="Aminotransferase class-III"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg16_25_0009"
                     /evalue="1.20E-78"
                     /label="ctg16_25"
                     /locus_tag="ctg16_25"
                     /protein_end="466"
                     /protein_start="78"
                     /score="264.7"
                     /tool="antismash"
                     /translation="TVFEKSKGYKLWDVDGKEYIDFFAGAGTLNYGHNDTKMQEKIIEY
                     IQQDGILHSLDMGTTPRKEFLETFQEIILTPRNLDYKVMFPGPTGTNSVESALKIARKV
                     TGRDTVISFTNAFHGMTIGSLSVTGNSFKRHGAGVPLHHTVSMPFDDYVEDQNSIAYIE
                     RFLEDSGSGVALPAAIILETVQGEGGINAARMDWLKKIERICRRWDILLIVDDIQAGCG
                     RTGTFFSFEPAGIKPDIVCLSKSIGGVGLPMALTLIKPEYDKWGPGEHNGTFRGNNLAF
                     IAAKEALRFWETDQFSSEIQDKAKLYKVKIDKIIAKYPELNGEARGRGLMQGIAVHVDD
                     LASKICTKAFERGLILETSGPNDEVVKFLPPLIIDEEGIMKGMAILDD"
     aSDomain        complement(5619..6620)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg16_25_Aminotran_3.1"
                     /evalue="6.40E-79"
                     /label="ctg16_25_Aminotran_3.1"
                     /locus_tag="ctg16_25"
                     /protein_end="414"
                     /protein_start="80"
                     /score="257.2"
                     /tool="antismash"
                     /translation="FEKSKGYKLWDVDGKEYIDFFAGAGTLNYGHNDTKMQEKIIEYIQ
                     QDGILHSLDMGTTPRKEFLETFQEIILTPRNLDYKVMFPGPTGTNSVESALKIARKVTG
                     RDTVISFTNAFHGMTIGSLSVTGNSFKRHGAGVPLHHTVSMPFDDYVEDQNSIAYIERF
                     LEDSGSGVALPAAIILETVQGEGGINAARMDWLKKIERICRRWDILLIVDDIQAGCGRT
                     GTFFSFEPAGIKPDIVCLSKSIGGVGLPMALTLIKPEYDKWGPGEHNGTFRGNNLAFIA
                     AKEALRFWETDQFSSEIQDKAKLYKVKIDKIIAKYPELNGEARGRGLMQGIAV"
     CDS             complement(6941..7546)
                     /locus_tag="ctg16_26"
                     /transl_table=11
                     /translation="LTKHFLPFKLINVLNNKNFLGGEIINISEVVDRLNIKTTEYHFRK
                     PNKDDGASVWELVKHTGNLDLNSSYSYLMWCEIFSDTSIVVVRKGAQKVVGFISGFIHP
                     EKEDTLFIWQVAVHESERGNGLATKMLLQLLDRDTSENVHYVEATVSPSNTPSKRLFLG
                     LARKFETNWVISDYFTSDDFPSLEHEEELLFKIGPFEK"
     aSDomain        complement(6947..7420)
                     /aSDomain="TIGR02406"
                     /aSTool="tigrfam"
                     /description="ectoine_EctA: diaminobutyrate
                     acetyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg16_26_0003"
                     /evalue="2.90E-58"
                     /identifier="TIGR02406"
                     /label="ctg16_26"
                     /locus_tag="ctg16_26"
                     /protein_end="200"
                     /protein_start="42"
                     /score="194.3"
                     /tool="antismash"
                     /translation="FRKPNKDDGASVWELVKHTGNLDLNSSYSYLMWCEIFSDTSIVVV
                     RKGAQKVVGFISGFIHPEKEDTLFIWQVAVHESERGNGLATKMLLQLLDRDTSENVHYV
                     EATVSPSNTPSKRLFLGLARKFETNWVISDYFTSDDFPSLEHEEELLFKIGPFE"
     PFAM_domain     complement(7064..7339)
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg16_26_0010"
                     /evalue="3.70E-13"
                     /label="ctg16_26"
                     /locus_tag="ctg16_26"
                     /protein_end="161"
                     /protein_start="69"
                     /score="49.8"
                     /tool="antismash"
                     /translation="YSYLMWCEIFSDTSIVVVRKGAQKVVGFISGFIHPEKEDTLFIWQ
                     VAVHESERGNGLATKMLLQLLDRDTSENVHYVEATVSPSNTPSKRLF"
     CDS             complement(7710..9353)
                     /locus_tag="ctg16_27"
                     /transl_table=11
                     /translation="MENMKWQTPEELRSLLAELVSWKSMTLSEGERQFPIKLQAKLQDL
                     TYFQKNPEYLKLHDADLRRKFLTALYKHPKAKKTICFISHFDTVNTEEYGDDEPLATQP
                     EELTKVWKERTDHLPNEVIHDIESGEYLFGRGTMDMKMGLVMHMRIIEKASVESWPINL
                     LLLTVPDEEVNSSGMRHAVPKLIEIQRKHHLTYSLFLNSEPVFSQNPNNDHHYFYTGSI
                     GKILAAALFYGKETHAGESLKGMTSPFISSYLTREMEWNASFQETVFNEKTPLPITLQQ
                     TDLRLLYSTQTPYRSSALYNIFVFRKNASEVFELFEQVAKQAAKKCNNDYKNICKANET
                     EPIGEVKVIKYKDLLQYAEKRFGTEFIKDIKSDIYYHEEWDDREKSLRMTDRLMIHCQE
                     LAPAIVVLLAPPYYPAVNSSNHPLVKKCSEYIIQRAKEKYQLTISQIHYFNGICDLSYV
                     NYNGPKEGWSAFEENTPVWGDTYSIPFEDMQKLQAPVLNVGPFGKDPHKRSERLHIQNA
                     FVETPVLLEDMIKMIINEKSIDEDKVNIKN"
     PFAM_domain     complement(8022..9032)
                     /aSDomain="Peptidase_M20"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01546.30"
                     /description="Peptidase family M20/M25/M40"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg16_27_0011"
                     /evalue="1.30E-08"
                     /label="ctg16_27"
                     /locus_tag="ctg16_27"
                     /protein_end="444"
                     /protein_start="107"
                     /score="34.9"
                     /tool="antismash"
                     /translation="TKVWKERTDHLPNEVIHDIESGEYLFGRGTMDMKMGLVMHMRIIE
                     KASVESWPINLLLLTVPDEEVNSSGMRHAVPKLIEIQRKHHLTYSLFLNSEPVFSQNPN
                     NDHHYFYTGSIGKILAAALFYGKETHAGESLKGMTSPFISSYLTREMEWNASFQETVFN
                     EKTPLPITLQQTDLRLLYSTQTPYRSSALYNIFVFRKNASEVFELFEQVAKQAAKKCNN
                     DYKNICKANETEPIGEVKVIKYKDLLQYAEKRFGTEFIKDIKSDIYYHEEWDDREKSLR
                     MTDRLMIHCQELAPAIVVLLAPPYYPAVNSSNHPLVKKCSEYIIQRAKEKYQLTIS"
ORIGIN
        1 catatctaac aaatgttgat ttgccctgtt cgttgataaa tcggaacgta ttaactggcc
       61 aagcttccat catccgccag cttcttggac ggccccgata ggacataagc cacataataa
      121 aatgggcaat ttcctgatta ttggagatat aatcccaggc attatcgtgc gcaacagttg
      181 cttgtgggac acctgtcctt ggattcggtt tgaccgcatg ggtaaaatcg gcaaatttca
      241 tggcatccat aatagcgaag atagcaaatg agagtgccag catatcataa tttccttctt
      301 gtgtgtaaaa cttggttgca aaaccacgta tatcaatggc tgtatccttg gaccctttac
      361 tccctataaa gttggaaaat cggacaaata caggtgtttt agtgccaggt tcttgcaaaa
      421 agtgtgctct tgttacatgt ttcatggatt tgtataactc aaattcccca tatgctccgt
      481 cacctcttgc atgaacaact ttttctggta tccgttcccg actaaaatgt gactgttttc
      541 tgtaaaaatg gaagtcctga aataatgtcg gcccccgctt tccggctctt aaggaccacc
      601 gatcgttcga aattttaaac ccagcgtcat ctgtcatttt ctcgccttta cctgtgtttt
      661 tctctctata ctgttccaac tgctcctgtt ttttatcttt atcaaactta ttgttatctc
      721 ttggtgactt atccatgtat tctatcatcc tttcttataa aaagctttaa acttaaactc
      781 gatatttata tgtatatgac tattccgcaa aattagaaca ttagggggaa aatgtggatt
      841 ttacagaatt ggctgattat attatcatta atttatacaa aaaaggggtg tttcatatgg
      901 actacaatat aatagaagaa atcgttacaa aaatttacca agctcgtgaa acaaaaactc
      961 caattgagtt tattcgaaat gattatactt tagatgaaaa tactgcatat gctgttcaag
     1021 atgagttaat gaagagaatt caagaagtac ataacgagga aattatcgga tataaaatta
     1081 gtatgacaag taaagaaaca caggctatag caaatactca tgaaccggca tacggaacat
     1141 tactcacttc caatattgtc gaatccggta acaatatttc cttatctaat ttatttgcac
     1201 cattagttga gccagaatta gtgtttatat taacagagga tttatcccct actgcaacag
     1261 aagaagaaat tcttaataag agtaagatag cagctggact tgagattcct gattcacgct
     1321 atatagattg gttccctaac ttctctttag ctgacctact ttccgatgat acagcaacag
     1381 gacttgtggt tgtttctgaa ggagttacgc caccttcatt ggatgaatta gctaatatta
     1441 aaatggaact gttccacaat ggtgaaaaaa ttagtgaggg tgtttcttca gcagtgttag
     1501 ataatccggt atctgctgta gcatggttag ttaaaaagct tgctagtcat cataaaacac
     1561 taaaaaaagg aatgatgatt tcttctggaa cctttatttc acctttacct gtacaagttg
     1621 gtaaatacga agcgtcttac tcctccatcg gaaaattaga agtcaccttt tcataacaaa
     1681 ggcgtaagtg cccttacagg ctaaaaacgc gacgtcctga cgcaactcct gtgcttcgta
     1741 gcaacataca aactgcactc cgcaataaca ggtggtccga ttgccgggcg cttcggggac
     1801 gcggcctggg atagtggaaa aacccctttt tatgagacta gttttcttgc ccttactctc
     1861 ttttgcctta tccatatact attattgtaa atggaggtga gattatgagt tacagcggcg
     1921 gttatggcgg aagtagtagc ttcgcgttaa ttgtagttct atttatcctt ttaattatcg
     1981 ttggaacttc ctatgttggt ggttactagt atgtaataaa tacggggatg cgacttcagc
     2041 atccccgtat ttttttattg ttgtggggaa gacggggtag aaatacttgc tagcgcttgt
     2101 ccagcttcat cagcatgttg attctgaact gctaaatctc ctaatgctac cattccaact
     2161 aactgaccat tttcctcaat tggcaatcga cgaatttgtt gctgtgacat taactctgca
     2221 gcctggtctg catccatatc tggagtacct tttaccattt gttgcgctgt cattacttcg
     2281 gaaaccggcg tttgtgcatt ttgtccttgt gctgttgtac gtaaagtgat atcacgatcc
     2341 gttacaatcc ctaccatttg acctccactg ttaacaacag gtaccgctcc aatattgtac
     2401 tggctcataa tagcagctgc ctcttgtacc gattgtgatt catttacggt cattacattt
     2461 tgcgtcatca tatttcttaa ttgtgtcatg taagtattac ctccttcacc cttagagtgg
     2521 tttaattttt cctagttata cctccttttc attaatacgt gataaagcca tcagtgggga
     2581 tctcccttca tcccccacta ataattagtc gcacttatcg tctttacggg cagtaaaact
     2641 cctacctcaa gcttctaggg ataaaagttt tccggaataa attcccattg ctatttttaa
     2701 aaaagttacc taaaataaga acatacgttt cataacttta ggcggtgaag atgatggatt
     2761 actctcctta tcctcggaat gatgtattat gtattgatat gcgttcattc tatgctagtg
     2821 tagaagcaat taaattagga cttgatccaa tgactacctt actcgcagta gttggggatc
     2881 ctaatcgttc gggcagtatt gtactggctg cttctccaac tttgaaaaaa aagtatagta
     2941 tcagcaatgt cagccgctac tttgaactac cgaaagatcc agatattcat attgttcctg
     3001 cacatatggc agattatctc catgtttcta ttgaaatcac aaaattaatt aaccaatatg
     3061 ttccgaaaga agccatccat caatactctg tggatgaagt ttgggttact gtaaatggat
     3121 tgaaaaagct tttcggtgat cgttgggaag tagcaaaaaa gatcaaacaa gatattttcg
     3181 atcattttgg aatcacttct tctattggaa ttggtgataa taagtttctt gctaaggtag
     3241 tgatggatat tcatgggaaa aaatccggga ttgccgaatg caaatatgaa gatgtagaag
     3301 aaaaactttg gccctttcct gttgaagaaa tttggggaat tggtagcaga atgaaacgca
     3361 atctcaatcg aatgggcatt gttactctcg gtcaacttgc caattatagt ttagaccact
     3421 taaaaagtcg ctttgggatt atgggggaac agttatactt tcatgcttgg ggaattgatt
     3481 taagtcccgt gtatggaaac tttacgaaaa cagaacaaaa agggtttggt catggaattg
     3541 ctttattacg tgattataca aaggaagaaa tttctacatg tattcttgat ttatgtgaag
     3601 aggtatgccg aagagcccga actgctgaca aggtaggaaa aaccattcac ctaggcatct
     3661 cttattccaa agatacaggt ggaggcggat tttctcgttc caaatcaatc gagattccga
     3721 caaatgtgac aatggatgtt catcatgttt gtatgcagct ttttcatcaa ttttacgatg
     3781 gctttagtaa tattcgtcat gtctacgtta cgttagataa cctctctaat aaagcagaaa
     3841 cccaactcga tttatttgaa gaccgttcaa aaaagacgga tattggatat gtcatggatg
     3901 cgattcgtga caaatatggt tctactgcta ttcttcgtgc ttctagttat acagctgctg
     3961 gcgtaaccct tgaacgtagt aaaaaaattg gaggccattt tgcatgatta gaaactcggt
     4021 attggatata ccaaaaatag acaaaccatt catagatgac ttaacatagt aaataccatg
     4081 ggaagaaatt taagattcca cgtcctcaca gaaggtatag aaaagaacta acaaatctat
     4141 taaaaaatct gattaaagga ggatttaaat gtatgaatta aagacaaaag aaaatgataa
     4201 tagtgtaatt gagtttattg aacaagtcga gaattcaaaa aaacgtgagg atgcctatcg
     4261 tttgctagat atcttcacag aaacgaccgg atacaaagca aaaatgtggg gaaccagcat
     4321 cattggcttc ggatcttatc attacaaata tgcaaccggc catgaaggcg atgcaccttt
     4381 agttggcttt tcaccgcgca aaaccaattt tagtttatat tttgctaccg gagatactga
     4441 acgtgatatg ttactacagg aattcggaaa acataaagca gggaaatctt gtgtatatat
     4501 aaataaaatc gccgacattg atgtggaagt gttaaagaaa ttaatccaac aatctattcg
     4561 atttctaagg gaaatgtatc ccgatacaaa gtaacatctc tccaattcaa ctagttgtac
     4621 aagtccaaat cattatgtaa gatagatgaa gaattaaaat ttaaaatcca taatgaaaaa
     4681 atgttggatt gtaaggaaag cgtgtttaat atgggattca tcattattga agtatgtgat
     4741 tacaatatac tctcttctga agaattagag gaagtattta accgtcccga agttgccgtc
     4801 atgagttatg aatgcatgaa ttattgtgga atgtgtgcaa tgagaccata tgccatggta
     4861 aacggaaaac gggtattcgg caaaacaaca gaagaatgta ttgaaaagat aaaaaaagaa
     4921 gtagagaagg aacttgaaga acttgaaaat ttttaaatag aaaagaacag atacaccgtg
     4981 tacctgttct tttatatacc ctattccgtt aatagtggat agtatccttc ttcattatgc
     5041 gtttccgtcc ctaccaaagg tggattaaat acgcaaatca tttgcattct ctttctaaca
     5101 cgtactatgt gtttatcatt ctgatctaat aaatacatcg tatgtggttt aagttgccac
     5161 acttcccctg tttctacctt ttcaatctca ccttcacctt caataagata aacggcttca
     5221 atatgatttt tataccaaaa gtaattttct gttccagctt caataactgt attcgtcata
     5281 ctgaaaccta caccgtcttt ctttaaaaca aatctgcggc tagcccatgt ttcccctttt
     5341 gtttcagctt ctgttcccat aatatcttca agtgatttta cgatcatatg gttcatctcc
     5401 ttttctattc gttttttata tatcctacgc gggaattagc tagatagaac ttgagcaatg
     5461 ctatcgtcta gaattgccat ccctttcatt atcccttctt catcaataat aagaggcgga
     5521 aggaacttaa caacttcatc attaggtcca gatgtttcta aaattagccc acgttcaaat
     5581 gcctttgtgc aaattttact agcgaggtca tcaacatgaa ccgcaattcc ttgcattaaa
     5641 cctctcccgc gagcttcccc atttaattca ggatatttgg cgattatctt gtctattttc
     5701 actttataca attttgcttt atcttgtatt tcgctggaga attgatccgt ttcccaaaat
     5761 ctaagtgctt cttttgctgc gataaatgct aggttgttac cgcggaaagt tccgttatgc
     5821 tcaccaggtc cccatttgtc atattcaggt ttaatcagtg ttagtgccat tggtagtcca
     5881 acgccgccga ttgatttaga aagacaaacg atatccggtt taatcccagc tggttcaaaa
     5941 ctaaagaatg taccagttct tccacatcct gcttgaatgt catcgacaat taatagaata
     6001 tcccaacgac gacaaatacg ctctattttc ttcagccagt ccatacgcgc agcattaatt
     6061 ccaccttctc cttgcaccgt ttctaaaata atcgctgcag gtaatgcaac accgctacca
     6121 ctatcttcta gaaatctttc aatatatgca atagagtttt gatcttccac ataatcatca
     6181 aaaggcatgg ataccgtatg gtggagcggt acaccagcac catggcgttt aaaagagtta
     6241 cctgtcacag ataatgatcc gattgtcatt ccatgaaacg cgtttgtaaa acttattacc
     6301 gtatcgcgcc ctgtaacttt cctagctatc ttcaatgcac tttctactga attggttcca
     6361 gttgggccag gaaacataac tttataatcg aggtttcgag gtgtaagtat gatttcttgg
     6421 aaggtttcta aaaattcttt tcttggagtt gttcccatat cgaggctatg aaggatccca
     6481 tcttgttgaa tatattcaat aattttttcc tgcattttcg tatcattatg cccatagttt
     6541 aatgtacctg ccccagcaaa aaaatcgata tattcttttc catctacatc ccatagttta
     6601 tatccttttg acttctcaaa tactgtaggc caaccacgac tgtagctcct aacagcagat
     6661 tccaatttct caaatgtttc catcttatta ttgtttatta cagcagtcgt cattatcatt
     6721 atctcatcct tttcaaggtt attcaaaaag tccggtgaaa atgacacgtc gatgtttcta
     6781 gttggcttgc ttttccgttc cttggaaaag aaaaccactt ttccggcgtg caagagcgtc
     6841 tgctcacgta ttaattgcat acgttccgct actcagagct acgccgcctc gaacttcttg
     6901 gtccttttca tccacctttt tgaacacgta ttttttattt ttatttttca aacggtccaa
     6961 ttttaaacaa cagttcctct tcatgttcta aacttggaaa gtcatccgaa gtaaaataat
     7021 cactaattac ccaatttgtc tcaaactttc ttgcaaggcc taagaataaa cgctttgaag
     7081 gagtatttga cggtgatacg gtcgcttcaa catagtgaac attttcactt gtatcacggt
     7141 caagtaactg taacaacatc tttgttgcca atccatttcc ccgttcagat tcatgaactg
     7201 caacctgcca aataaacaac gtatcttcct tttctggatg aataaatcca gaaataaaac
     7261 caacgacttt ttgtgcacct tttcttacca ctacaataga agtatcggaa aaaatctcac
     7321 accacattaa atagctataa gaagaattga gatctaaatt tccagtatgt ttaacaagct
     7381 cccaaacaga agccccgtca tctttattcg gcttacggaa atggtattcc gtggtcttta
     7441 tattcaatct atccactact tctgaaatat taatgatttc acctccgaga aaatttttat
     7501 tattcaatac gttaattagc ttaaatggta aaaaatgttt cgtcaaaata gataaaattg
     7561 gataagatgt gtttaaacat catgcgctac cattcataaa caatacatgc caaaacctat
     7621 taaatactaa gctatagtgt caaataatat gttttttaaa taatcctgta taatcaaaaa
     7681 ctagcaatcc cttatggggc aagggattgc tagtttttga tatttacttt atcttcgtca
     7741 atactttttt catttatgat cattttaatc atgtcttcca ataaaaccgg agtttctaca
     7801 aaggcatttt gtatatgcaa acgttccgaa cgtttatgtg gatctttgcc gaaaggaccg
     7861 acatttaata caggagcttg cagtttttgc atatcttcaa aggggataga atacgtatct
     7921 ccccaaaccg gtgtattctc ttcaaatgca ctccaccctt ccttaggacc gttataatta
     7981 acataactta aatcacaaat accattaaag taatggattt gactaatcgt cagttgatat
     8041 ttttcctttg ccctctgtat gatatattcg gagcatttct tgactaatgg atgattagac
     8101 gaattaactg ccggataata cggaggagca agtaatacaa caatagccgg tgccaactct
     8161 tgacaatgaa tcatcaatcg atccgtcata cgaagtgatt tttcccggtc atcccattcc
     8221 tcgtgataat aaatatcaga tttaatatct ttaatgaatt cggtaccaaa ccttttctcg
     8281 gcatattgta ataaatcttt atatttaata acttttactt cgccaatggg ctcagtttca
     8341 ttagctttac atatattttt ataatcgtta ttacattttt ttgccgcttg tttcgctact
     8401 tgctcgaaca gttcgaaaac ttctgatgca ttttttctaa atacaaaaat attatatagt
     8461 gcggaagaac gataaggggt ttgagtggaa tataaaagcc ttaaatccgt ttgttgtaaa
     8521 gttattggca gaggagtttt ttcattgaac accgtttctt gaaaactagc attccattcc
     8581 atttctctcg ttaaataaga acttataaac ggtgaggtca tcccttttaa tgattcgcct
     8641 gcatgtgtct ctttcccata gaataatgca gccgctaata ttttcccaat ggaacctgtg
     8701 taaaaatagt gatgatcgtt atttggattc tgggaaaata ccggttcact atttaaaaac
     8761 aaactgtatg ttaaatgatg tttcctttgt atctcgatta gtttcggaac cgcatggcgc
     8821 atcccagatg aatttacttc ctcatcaggt acagtaagca acaatagatt aattggccaa
     8881 ctttctacac ttgctttttc aattatacgc atatgcatca caagtcccat cttcatatcc
     8941 atggtgcccc gtccaaataa atattcacca gattcaatat cgtgaataac ctcattaggt
     9001 aaatgatccg ttcgttcttt ccaaaccttc gttaattcct ccggttgtgt tgcaagcggt
     9061 tcatcatctc catattcttc cgtatttacc gtatcaaaat gactaatgaa gcaaatcgtc
     9121 tttttcgctt ttggatgttt ataaagtgca gttagaaatt ttcttcgtag gtcagcatca
     9181 tgcaatttaa gatattccgg atttttttga aaataagtca aatcctgtag ctttgcttgt
     9241 aatttaatag gaaactgtct ttccccttct gacaatgtca tacttttcca actaacaagc
     9301 tccgctaaca aactccgtaa ttcttctggt gtctgccatt tcatattctc catctctcat
     9361 tcattcctcc tatccaaaag gaaacaatct attcttacca tattatattc attccattat
     9421 aattttgtca taagacaaga tagaaaaaga taaaatggaa aaagtgatac ttattcagtc
     9481 gattttcttt tatcttctac ctgagttaat acttaacgga gacagattat tattttaaga
     9541 tataaagaag acttccatca ttggggtttt tccctcaggc agttgatctc ccacctgcct
     9601 tctttgtttc cccagaagct tgcaggtggt agttttattg cctgtttagg tgggaaatat
     9661 aaattctttt agactaaaga aaggtgagga tacatttgaa atctggctta aacattctta
     9721 tcttaggtgg cgataaccgc tacctagaag taataaatat attagcttcg aataatatga
     9781 atatattttt aaatggattt aacaaattat ctttcgagga tccatctatc cataatctag
     9841 aaacatcaga aattgatttt agtatcatgg atgcgatttt actccccgca tccggaacag
     9901 ataaagatgg tgaaatagaa gctacatatt ctaatacatc gattagatta acagaaaaac
     9961 aattacaaca aacacctgac cattgtacga tttatactgg aatatccaac gactttttag
    10021 ataaaataac gcactcaagt aatcgaaaaa tggttcgttt atttgctcgt aacgatattg
    10081 ccatctataa ttcaatccct accgctgaag ctacattaaa aatcgcaata gaagaaacag
    10141 atgtaacgat acacggatct gaagttctcg taataggttt tgggagagtt ggaataacgg
    10201 tagctcgcct ttttgcagca ttaggagcga aagtaacggt tgctgccaga aagtcggaac
    10261 attttgctcg catagcggaa atggggttaa aatccattga gaccagtagg gtagaaaata
    10321 tcgtaacgaa tatggatatt tgcattaata cggttcccca ttccatcatc ggtccaaaaa
    10381 tcataga
//
