GCF_000736675.1_XBFFL_3524_PRJEB4320_genomic - 27 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_HG426725.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS	1	3,542	xenematide	NRP	100%

NZ_HG426726.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	NRPS	1	10,715	taxlllaid A	NRP	4%

NZ_HG426732.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	siderophore	34,255	57,364	putrebactin / avaroferrin	Other	90%

NZ_HG426745.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 19.1	RiPP-like	1	4,225

NZ_HG426747.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	NRPS	1	42,610

NZ_HG426750.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 24.1	NRPS,T1PKS	1	96,781	glidopeptin	NRP	37%

NZ_HG426798.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 61.1	NRPS-like	14,248	54,214

NZ_HG426803.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 65.1	NRPS-like	1	33,881

NZ_HG426804.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 66.1	betalactone	1	24,132	lipopolysaccharide	Saccharide:Lipopolysaccharide	5%

NZ_HG426809.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 69.1	NRPS	6,352	50,542	xenoamicin A / xenoamicin B	NRP:Cyclic depsipeptide	25%

NZ_HG426823.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 81.1	NRPS	1	38,946

NZ_HG426825.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 83.1	arylpolyene	1	27,821	aryl polyenes	Other	100%

NZ_HG426828.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 86.1	PUFA,hglE-KS	31,035	82,450	fabclavine-polyamine	Polyketide	90%

NZ_HG426829.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 87.1	NRPS	1	2,102	tolaasin I / tolaasin F	NRP:Lipopeptide	40%

NZ_HG426830.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 88.1	NRPS	13,633	37,155	taxlllaid A	NRP	33%

NZ_HG426843.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 97.1	thiopeptide,NRPS-like	1	13,062

NZ_HG426848.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 101.1	T1PKS	1	16,906

NZ_HG426849.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 102.1	NRPS	7,565	57,757	ambactin	NRP	50%

NZ_HG426861.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 108.1	NRPS-like,betalactone	1	26,525

NZ_HG426875.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 118.1	NRPS-like,T1PKS,CDPS	1	28,089

NZ_HG426883.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 125.1	NRPS,T1PKS	1	61,207	xenocoumacin 1 / xenocoumacin II	NRP + Polyketide:Modular type I	14%

NZ_HG426887.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 129.1	ladderane	1	40,789

NZ_HG426895.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 134.1	NRPS-like	1	15,225	taxlllaid A	NRP	17%

NZ_HG426914.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 147.1	PpyS-KS	233	20,729

NZ_HG426925.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 155.1	NRPS	47,089	90,499	thiomarinol	NRP + Polyketide	16%

NZ_HG426926.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 156.1	NRPS	63	76,779	xefoampeptides A-G	NRP	50%

NZ_HG426951.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 181.1	T1PKS,NRPS,NRPS-like	1	59,356	xenocoumacin 1 / xenocoumacin II	NRP + Polyketide:Modular type I	78%

No secondary metabolite regions were found in these records:: NZ_HG426727.1; NZ_HG426729.1; NZ_HG426731.1; NZ_HG426733.1; NZ_HG426734.1; NZ_HG426735.1; NZ_HG426736.1; NZ_HG426737.1; NZ_HG426738.1; NZ_HG426739.1; NZ_HG426740.1; NZ_HG426741.1; NZ_HG426742.1; NZ_HG426743.1; NZ_HG426744.1; NZ_HG426746.1; NZ_HG426748.1; NZ_HG426749.1; NZ_HG426751.1; NZ_HG426752.1; NZ_HG426753.1; NZ_HG426755.1; NZ_HG426756.1; NZ_HG426758.1; NZ_HG426759.1; NZ_HG426760.1; NZ_HG426761.1; NZ_HG426762.1; NZ_HG426763.1; NZ_HG426764.1; NZ_HG426765.1; NZ_HG426768.1; NZ_HG426769.1; NZ_HG426770.1; NZ_HG426771.1; NZ_HG426772.1; NZ_HG426773.1; NZ_HG426775.1; NZ_HG426779.1; NZ_HG426780.1; NZ_HG426781.1; NZ_HG426782.1; NZ_HG426784.1; NZ_HG426785.1; NZ_HG426786.1; NZ_HG426787.1; NZ_HG426788.1; NZ_HG426790.1; NZ_HG426791.1; NZ_HG426793.1; NZ_HG426794.1; NZ_HG426795.1; NZ_HG426796.1; NZ_HG426797.1; NZ_HG426800.1; NZ_HG426801.1; NZ_HG426802.1; NZ_HG426805.1; NZ_HG426808.1; NZ_HG426810.1; NZ_HG426811.1; NZ_HG426812.1; NZ_HG426813.1; NZ_HG426814.1; NZ_HG426816.1; NZ_HG426818.1; NZ_HG426819.1; NZ_HG426820.1; NZ_HG426821.1; NZ_HG426822.1; NZ_HG426824.1; NZ_HG426826.1; NZ_HG426827.1; NZ_HG426831.1; NZ_HG426832.1; NZ_HG426835.1; NZ_HG426836.1; NZ_HG426838.1; NZ_HG426839.1; NZ_HG426841.1; NZ_HG426842.1; NZ_HG426844.1; NZ_HG426845.1; NZ_HG426847.1; NZ_HG426850.1; NZ_HG426856.1; NZ_HG426858.1; NZ_HG426859.1; NZ_HG426860.1; NZ_HG426862.1; NZ_HG426863.1; NZ_HG426864.1; NZ_HG426865.1; NZ_HG426866.1; NZ_HG426868.1; NZ_HG426869.1; NZ_HG426870.1; NZ_HG426874.1; NZ_HG426876.1; NZ_HG426877.1; NZ_HG426878.1; NZ_HG426880.1; NZ_HG426881.1; NZ_HG426882.1; NZ_HG426884.1; NZ_HG426885.1; NZ_HG426886.1; NZ_HG426891.1; NZ_HG426892.1; NZ_HG426893.1; NZ_HG426894.1; NZ_HG426896.1; NZ_HG426897.1; NZ_HG426898.1; NZ_HG426903.1; NZ_HG426905.1; NZ_HG426906.1; NZ_HG426907.1; NZ_HG426908.1; NZ_HG426909.1; NZ_HG426911.1; NZ_HG426912.1; NZ_HG426913.1; NZ_HG426916.1; NZ_HG426918.1; NZ_HG426919.1; NZ_HG426920.1; NZ_HG426921.1; NZ_HG426922.1; NZ_HG426923.1; NZ_HG426927.1; NZ_HG426928.1; NZ_HG426929.1; NZ_HG426930.1; NZ_HG426931.1; NZ_HG426932.1; NZ_HG426933.1; NZ_HG426934.1; NZ_HG426935.1; NZ_HG426936.1; NZ_HG426937.1; NZ_HG426938.1; NZ_HG426939.1; NZ_HG426940.1; NZ_HG426941.1; NZ_HG426942.1; NZ_HG426943.1; NZ_HG426944.1; NZ_HG426945.1; NZ_HG426946.1; NZ_HG426947.1; NZ_HG426948.1; NZ_HG426949.1; NZ_HG426950.1; NZ_HG426952.1; NZ_HG426953.1; NZ_HG426954.1; NZ_HG426955.1; NZ_HG426956.1; NZ_HG426958.1; NZ_HG426959.1; NZ_HG426960.1

Compact view

NZ_HG426725.1 - Region 1 - NRPS

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Location: 1 - 3,542 nt. (total: 3,542 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001825.1	0.28	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001844.1	0.22	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758.1	0.22	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001132.1	0.22	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001641.1	0.22	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001479.1	0.22	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001128.1	0.22	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000307.1	0.22	NRP	AbT1	Aureobasidium pullulans
BGC0001135.1	0.22	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001833.1	0.22	NRP	icosalide A, icosalide B	Burkholderia gladioli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001825.1	0.61	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001844.1	0.56	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758.1	0.55	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001132.1	0.55	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001641.1	0.55	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001479.1	0.55	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001128.1	0.55	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000307.1	0.55	NRP	AbT1	Aureobasidium pullulans
BGC0001135.1	0.55	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001833.1	0.55	NRP	icosalide A, icosalide B	Burkholderia gladioli

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 3542:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1

Search NORINE for peptide: strict or relaxed

AMP-binding (18..419): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFhGqVcK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)

NZ_HG426726.1 - Region 1 - NRPS

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Location: 1 - 10,715 nt. (total: 10,715 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001479.1	0.35	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001133.1	0.34	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001825.1	0.33	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001132.1	0.28	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001135.1	0.27	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000404.1	0.26	NRP	penicillin	Penicillium chrysogenum
BGC0001128.1	0.26	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000313.1	0.26	NRP	beauvericin	Beauveria bassiana
BGC0001873.1	0.26	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000342.1	0.26	NRP	enniatin	Fusarium equiseti

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001479.1	0.68	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001133.1	0.67	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001825.1	0.66	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001132.1	0.61	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001135.1	0.60	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000404.1	0.60	NRP	penicillin	Penicillium chrysogenum
BGC0001128.1	0.60	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000313.1	0.60	NRP	beauvericin	Beauveria bassiana
BGC0001873.1	0.59	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000342.1	0.59	NRP	enniatin	Fusarium equiseti

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 10715:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser - leu - D-leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg2_2

Search NORINE for peptide: strict or relaxed

AMP-binding (53..470): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLIEK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

AMP-binding (1114..1515): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFhGqVcK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)

AMP-binding (2159..2560): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFhGqVcK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)

NZ_HG426732.1 - Region 1 - siderophore

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Location: 34,255 - 57,364 nt. (total: 23,110 nt) Show pHMM detection rules used

siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001870.1	0.50	Other	putrebactin, avaroferrin	Xenorhabdus budapestensis
BGC0001572.1	0.31	Other	desferrioxamine E	Pantoea agglomerans
BGC0000942.1	0.25	Other	petrobactin	Bacillus anthracis str. Ames
BGC0000295.1	0.22	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001478.1	0.22	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0001453.1	0.21	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.21	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0000941.1	0.21	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000939.1	0.20	Other	aerobactin	Grimontia hollisae
BGC0001499.1	0.20	Other	aerobactin	Pantoea ananatis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001870.1	0.79	Other	putrebactin, avaroferrin	Xenorhabdus budapestensis
BGC0001572.1	0.64	Other	desferrioxamine E	Pantoea agglomerans
BGC0000942.1	0.59	Other	petrobactin	Bacillus anthracis str. Ames
BGC0000295.1	0.55	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001478.1	0.55	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0001453.1	0.54	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.54	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0000941.1	0.54	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000939.1	0.52	Other	aerobactin	Grimontia hollisae
BGC0001499.1	0.52	Other	aerobactin	Pantoea ananatis

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_HG426745.1 - Region 1 - RiPP-like

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Location: 1 - 4,225 nt. (total: 4,225 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002004.1	0.23	RiPP	methanobactin	Methylosinus trichosporium OB3b
BGC0001486.1	0.12	RiPP	3-thiaglutamate	Pseudomonas syringae pv. maculicola str. ES4326
BGC0002027.1	0.12	RiPP	TglA-thiaGlu	Pseudomonas syringae pv. maculicola str. ES4326
BGC0000632.1	0.05	Terpene, Saccharide	brasilicardin A	Nocardia terpenica

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002004.1	0.56	RiPP	methanobactin	Methylosinus trichosporium OB3b
BGC0001486.1	0.39	RiPP	3-thiaglutamate	Pseudomonas syringae pv. maculicola str. ES4326
BGC0002027.1	0.39	RiPP	TglA-thiaGlu	Pseudomonas syringae pv. maculicola str. ES4326
BGC0000632.1	0.21	Terpene, Saccharide	brasilicardin A	Nocardia terpenica

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

NZ_HG426747.1 - Region 1 - NRPS

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Location: 1 - 42,610 nt. (total: 42,610 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001873.1	0.43	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000427.1	0.33	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000900.1	0.30	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.30	NRP	dimethylcoprogen	Alternaria alternata
BGC0001561.1	0.28	NRP	curacomycin	Streptomyces curacoi
BGC0001479.1	0.26	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001399.1	0.25	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001718.1	0.23	NRP	okaramine D	Aspergillus aculeatus ATCC 16872
BGC0001261.1	0.23	NRP	AM-toxin	Alternaria alternata
BGC0001132.1	0.23	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001873.1	0.74	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000427.1	0.66	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000900.1	0.64	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.64	NRP	dimethylcoprogen	Alternaria alternata
BGC0001561.1	0.62	NRP	curacomycin	Streptomyces curacoi
BGC0001479.1	0.60	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001399.1	0.58	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001718.1	0.57	NRP	okaramine D	Aspergillus aculeatus ATCC 16872
BGC0001261.1	0.57	NRP	AM-toxin	Alternaria alternata
BGC0001132.1	0.56	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061

Similar known gene clusters

No matches found.

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 42610:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser - pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg21_13

Search NORINE for peptide: strict or relaxed

AMP-binding (444..851): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

AMP-binding (1509..1905): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFvsqVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 70% (weak)

NZ_HG426750.1 - Region 1 - NRPS,T1PKS

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Location: 1 - 96,781 nt. (total: 96,781 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000389.1	0.84	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001050.1	0.71	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000427.1	0.69	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000979.1	0.69	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.69	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0000438.1	0.69	NRP	syringopeptin 25A	Pseudomonas syringae pv. syringae
BGC0000375.1	0.68	NRP	indigoidine	Streptomyces chromofuscus
BGC0001132.1	0.66	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001128.1	0.65	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758.1	0.63	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000389.1	0.79	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000438.1	0.73	NRP	syringopeptin 25A	Pseudomonas syringae pv. syringae
BGC0001050.1	0.71	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0001758.1	0.71	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001641.1	0.71	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1	0.71	NRP	ambactin	Xenorhabdus miraniensis
BGC0001128.1	0.71	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001132.1	0.70	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001135.1	0.70	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001844.1	0.70	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 96781:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - thr - ala) + (ala - phe - thr - val) + (ile - ile) + (pro - ala - val - phe - phe - ala - ile - val - ala) + (X) + (X) + (ccmal) + (asp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg24_8

Search NORINE for peptide: strict or relaxed

AMP-binding (509..905): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHVGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

ctg24_9

PKS_AT (531..820): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 75.0%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 149.1
inactive: 108.0
Methoxymalonyl-CoA: 65.1
Methylmalonyl-CoA: 63.3
Propionyl-CoA: 47.2
Ethylmalonyl-CoA: 37.2
Benzoyl-CoA: 28.4
Isobutyryl-CoA: 25.9
CHC-CoA: 23.8
2-Methylbutyryl-CoA: 20.9
Acetyl-CoA: 12.0
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

ctg24_10

Search NORINE for peptide: strict or relaxed

AMP-binding (13..407): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DvWQFGLIfK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 80% (moderate)

ctg24_11

Search NORINE for peptide: strict or relaxed

AMP-binding (11..409): X

NRPSPredictor2: orn, lys, arg

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: aaAyFSLAnK
Nearest Stachelhaus code:: beta-ala
Stachelhaus code match:: 60% (weak)

ctg24_13

Search NORINE for peptide: strict or relaxed

AMP-binding (487..895): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)

AMP-binding (1555..1948): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

AMP-binding (2628..3030): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAwWLGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

AMP-binding (3691..4085): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWlIgAVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 80% (moderate)

AMP-binding (4765..5159): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWlIgAVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 80% (moderate)

AMP-binding (5819..6212): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

AMP-binding (6892..7294): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAwFLGVTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

AMP-binding (7954..8357): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAwWLGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

AMP-binding (9037..9430): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

ctg24_14

Search NORINE for peptide: strict or relaxed

AMP-binding (505..907): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAwFLGVTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

AMP-binding (1590..1992): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAwFLGVTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

ctg24_15

Search NORINE for peptide: strict or relaxed

AMP-binding (503..896): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

AMP-binding (1576..1974): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWlIgAVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 80% (moderate)

AMP-binding (2634..3044): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

AMP-binding (3724..4131): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAwWLGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

ctg24_16

Search NORINE for peptide: strict or relaxed

AMP-binding (590..992): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: VDtVISfgDK
Nearest Stachelhaus code:: ala-b
Stachelhaus code match:: 70% (weak)

AMP-binding (1675..2085): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

AMP-binding (2768..3161): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

NZ_HG426798.1 - Region 1 - NRPS-like

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Location: 14,248 - 54,214 nt. (total: 39,967 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001168.1	0.32	NRP	livipeptin	Streptomyces lividans 1326
BGC0001900.1	0.32	NRP	fragin	Burkholderia cenocepacia H111
BGC0001599.1	0.27	NRP	fragin	Burkholderia cenocepacia H111
BGC0001399.1	0.25	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000427.1	0.21	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.21	NRP	indigoidine	Streptomyces chromofuscus
BGC0001131.1	0.18	NRP	ambactin	Xenorhabdus miraniensis
BGC0001128.1	0.18	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758.1	0.18	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001844.1	0.18	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001168.1	0.66	NRP	livipeptin	Streptomyces lividans 1326
BGC0001900.1	0.65	NRP	fragin	Burkholderia cenocepacia H111
BGC0001599.1	0.61	NRP	fragin	Burkholderia cenocepacia H111
BGC0001399.1	0.59	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000427.1	0.54	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.53	NRP	indigoidine	Streptomyces chromofuscus
BGC0001131.1	0.50	NRP	ambactin	Xenorhabdus miraniensis
BGC0001128.1	0.50	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758.1	0.50	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001844.1	0.50	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 14247 - 54214:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg61_32

Search NORINE for peptide: strict or relaxed

AMP-binding (51..441): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

NZ_HG426803.1 - Region 1 - NRPS-like

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Location: 1 - 33,881 nt. (total: 33,881 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.32	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.31	NRP	indigoidine	Streptomyces chromofuscus
BGC0000900.1	0.27	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.27	NRP	dimethylcoprogen	Alternaria alternata
BGC0000885.1	0.26	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0001561.1	0.26	NRP	curacomycin	Streptomyces curacoi
BGC0000979.1	0.25	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.25	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0000876.1	0.24	Other	neopolyoxin C	Streptomyces tendae
BGC0000294.1	0.24	NRP	acinetobactin	Acinetobacter baumannii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.66	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.65	NRP	indigoidine	Streptomyces chromofuscus
BGC0000900.1	0.61	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.61	NRP	dimethylcoprogen	Alternaria alternata
BGC0000885.1	0.59	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0001561.1	0.59	NRP	curacomycin	Streptomyces curacoi
BGC0000979.1	0.59	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.59	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0000876.1	0.58	Other	neopolyoxin C	Streptomyces tendae
BGC0000294.1	0.57	NRP	acinetobactin	Acinetobacter baumannii

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 33881:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg65_12

Search NORINE for peptide: strict or relaxed

AMP-binding (64..472): X

NRPSPredictor2: orn, lys, arg

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAwqLGVcnK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 60% (weak)

NZ_HG426804.1 - Region 1 - betalactone

Download region GenBank file

Download region SVG

Location: 1 - 24,132 nt. (total: 24,132 nt) Show pHMM detection rules used

Region on contig edge.

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000783.1	0.23	Saccharide	O-antigen	Xanthomonas oryzae pv. oryzae
BGC0000904.1	0.21	Other	FR-900098	Streptomyces rubellomurinus
BGC0001859.1	0.20	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000886.1	0.18	Other	allylmalonyl-CoA	Streptomyces tsukubensis
BGC0000841.1	0.15	Other (Non-NRP beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate, clavulanic acid	Streptomyces clavuligerus ATCC 27064
BGC0000774.1	0.15	Saccharide	lipopolysaccharide	Xanthomonas campestris pv. campestris
BGC0000896.1	0.15	Other	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0001587.1	0.14	Other	ethylenediaminesuccinic acid hydroxyarginine (EDHA)	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000815.1	0.14	Alkaloid	loline	Epichloe uncinata
BGC0001128.1	0.14	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000783.1	0.56	Saccharide	O-antigen	Xanthomonas oryzae pv. oryzae
BGC0000904.1	0.53	Other	FR-900098	Streptomyces rubellomurinus
BGC0001859.1	0.52	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000886.1	0.50	Other	allylmalonyl-CoA	Streptomyces tsukubensis
BGC0000841.1	0.46	Other (Non-NRP beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate, clavulanic acid	Streptomyces clavuligerus ATCC 27064
BGC0000774.1	0.44	Saccharide	lipopolysaccharide	Xanthomonas campestris pv. campestris
BGC0000896.1	0.44	Other	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0001587.1	0.44	Other	ethylenediaminesuccinic acid hydroxyarginine (EDHA)	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000815.1	0.43	Alkaloid	loline	Epichloe uncinata
BGC0001128.1	0.43	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_HG426809.1 - Region 1 - NRPS

Download region GenBank file

Download region SVG

Location: 6,352 - 50,542 nt. (total: 44,191 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001758.1	0.38	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0000426.1	0.38	NRP	sevadicin	Paenibacillus larvae
BGC0001131.1	0.38	NRP	ambactin	Xenorhabdus miraniensis
BGC0000389.1	0.37	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000438.1	0.37	NRP	syringopeptin 25A	Pseudomonas syringae pv. syringae
BGC0001844.1	0.37	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001833.1	0.35	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001135.1	0.35	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001128.1	0.34	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000331.1	0.34	NRP	cyanopeptin	Planktothrix agardhii NIVA-CYA 116

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001758.1	0.71	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0000426.1	0.70	NRP	sevadicin	Paenibacillus larvae
BGC0001131.1	0.70	NRP	ambactin	Xenorhabdus miraniensis
BGC0000389.1	0.70	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000438.1	0.69	NRP	syringopeptin 25A	Pseudomonas syringae pv. syringae
BGC0001844.1	0.69	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001833.1	0.68	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001135.1	0.68	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001128.1	0.68	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000331.1	0.67	NRP	cyanopeptin	Planktothrix agardhii NIVA-CYA 116

Similar known gene clusters

Module view

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Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 6351 - 50542:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser) + (X - X - X) + (X - X - pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg69_26

Search NORINE for peptide: strict or relaxed

AMP-binding (487..893): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHLSLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg69_27

Search NORINE for peptide: strict or relaxed

AMP-binding (511..924): X

NRPSPredictor2: glu, gln

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DnaDAGtVnK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 60% (weak)

AMP-binding (1585..1998): X

NRPSPredictor2: tyr, bht

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: tyr, bht
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DtsDtGtVsK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 50% (weak)

AMP-binding (2688..3104): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DtsDtGsViK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 50% (weak)

ctg69_28

Search NORINE for peptide: strict or relaxed

AMP-binding (511..927): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DtseTGtViK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 50% (weak)

AMP-binding (1611..2024): X

NRPSPredictor2: tyr, bht

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: tyr, bht
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DtsDtGtVsK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 50% (weak)

AMP-binding (2709..3118): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVLqtGLICK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 80% (moderate)

NZ_HG426823.1 - Region 1 - NRPS

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Location: 1 - 38,946 nt. (total: 38,946 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

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NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000389.1	0.32	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000373.1	0.25	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001806.1	0.25	NRP	tolaasin A	Pseudomonas tolaasii
BGC0000412.1	0.24	NRP	pyochelin	Pseudomonas aeruginosa PAO1
BGC0001469.1	0.23	NRP	marthiapeptide A	Brevibacillus sp. Leaf182
BGC0001790.1	0.21	NRP	sulfazecin	Pseudomonas acidophila
BGC0000410.1	0.21	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001758.1	0.21	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001844.1	0.21	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000343.1	0.21	NRP	enterobactin	Pseudomonas sp. J465

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000389.1	0.65	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000373.1	0.58	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001806.1	0.58	NRP	tolaasin A	Pseudomonas tolaasii
BGC0000412.1	0.57	NRP	pyochelin	Pseudomonas aeruginosa PAO1
BGC0001469.1	0.56	NRP	marthiapeptide A	Brevibacillus sp. Leaf182
BGC0001790.1	0.53	NRP	sulfazecin	Pseudomonas acidophila
BGC0000410.1	0.53	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001758.1	0.53	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001844.1	0.53	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000343.1	0.53	NRP	enterobactin	Pseudomonas sp. J465

Similar known gene clusters

No matches found.

Module view

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Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 38946:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys - cys) + (Me-cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg81_8

Search NORINE for peptide: strict or relaxed

AMP-binding (532..925): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

ctg81_9

Search NORINE for peptide: strict or relaxed

CAL_domain (126..396): pk

minowa: NH2

Prediction, score:

NH2: 73.2
Acetyl-CoA: 43.8
fatty_acid: 18.5
AHBA: 17.3
shikimic_acid: 0.0

AMP-binding (1595..1996): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

AMP-binding (3006..3406): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLwNMSMIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 90% (moderate)

NZ_HG426825.1 - Region 1 - arylpolyene

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Location: 1 - 27,821 nt. (total: 27,821 nt) Show pHMM detection rules used

Region on contig edge.

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.63	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.51	Other	APE Ec	Escherichia coli CFT073
BGC0000837.1	0.27	Other	APE Vf	Aliivibrio fischeri ES114
BGC0001075.1	0.25	Terpene, Polyketide	aurachin RE	Rhodococcus erythropolis
BGC0001723.1	0.24	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000231.1	0.24	Polyketide	griseusin	Streptomyces griseus
BGC0000234.1	0.22	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000228.1	0.21	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000248.1	0.21	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000272.1	0.21	Polyketide	spore pigment	Streptomyces collinus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.85	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.79	Other	APE Ec	Escherichia coli CFT073
BGC0000837.1	0.60	Other	APE Vf	Aliivibrio fischeri ES114
BGC0001075.1	0.58	Terpene, Polyketide	aurachin RE	Rhodococcus erythropolis
BGC0001723.1	0.58	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000231.1	0.58	Polyketide	griseusin	Streptomyces griseus
BGC0000234.1	0.55	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000228.1	0.54	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000248.1	0.54	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000272.1	0.54	Polyketide	spore pigment	Streptomyces collinus

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_HG426828.1 - Region 1 - PUFA,hglE-KS

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Location: 31,035 - 82,450 nt. (total: 51,416 nt) Show pHMM detection rules used

PUFA: PUFA_KS
hglE-KS: (hglE or hglD)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001872.1	1.27	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004
BGC0000863.1	0.58	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000889.1	0.52	Other	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0000861.1	0.49	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0002029.1	0.48	Other	bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C	Streptomyces lunaelactis
BGC0001592.1	0.48	Other	ferroverdin	Streptomyces lunaelactis
BGC0000284.1	0.47	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0000056.1	0.47	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000858.1	0.47	Other	ectoine	Methylobacter marinus
BGC0001730.1	0.47	Polyketide	paramagnetoquinone 1, paramagnetoquinone 2	Actinoallomurus sp.

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001872.1	0.86	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004
BGC0000863.1	0.63	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000889.1	0.63	Other	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0002029.1	0.60	Other	bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C	Streptomyces lunaelactis
BGC0001592.1	0.60	Other	ferroverdin	Streptomyces lunaelactis
BGC0001730.1	0.58	Polyketide	paramagnetoquinone 1, paramagnetoquinone 2	Actinoallomurus sp.
BGC0000861.1	0.58	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0000284.1	0.57	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0000056.1	0.57	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000858.1	0.57	Other	ectoine	Methylobacter marinus

Similar known gene clusters

Module view

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Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 31034 - 82450:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 35616 - 82450:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg86_36

Search NORINE for peptide: strict or relaxed

AMP-binding (26..203): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: De--cD---K
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 30% (weak)

ctg86_42

PKS_AT (593..896): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 40.5
Methoxymalonyl-CoA: 28.7
Methylmalonyl-CoA: 22.3
Acetyl-CoA: 19.5
fatty_acid: 12.8
inactive: 12.3
Isobutyryl-CoA: 12.3
Benzoyl-CoA: 10.7
CHC-CoA: 9.8
trans-1,2-CPDA: 0.0
Propionyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

NZ_HG426829.1 - Region 1 - NRPS

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Location: 1 - 2,102 nt. (total: 2,102 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Pfam domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001825.1	0.29	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001133.1	0.27	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0000396.1	0.24	NRP	nodularin	Nostoc sp. 73.1
BGC0001806.1	0.24	NRP	tolaasin A	Pseudomonas tolaasii
BGC0001135.1	0.24	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000426.1	0.24	NRP	sevadicin	Paenibacillus larvae
BGC0001758.1	0.23	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0000465.1	0.23	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0001132.1	0.23	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001128.1	0.23	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001825.1	0.63	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001133.1	0.61	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0000396.1	0.57	NRP	nodularin	Nostoc sp. 73.1
BGC0001806.1	0.57	NRP	tolaasin A	Pseudomonas tolaasii
BGC0001135.1	0.57	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000426.1	0.57	NRP	sevadicin	Paenibacillus larvae
BGC0001758.1	0.57	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0000465.1	0.57	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0001132.1	0.57	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001128.1	0.57	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

NZ_HG426830.1 - Region 1 - NRPS

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Location: 13,633 - 37,155 nt. (total: 23,523 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001825.1	0.33	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001133.1	0.31	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0000342.1	0.25	NRP	enniatin	Fusarium equiseti
BGC0001873.1	0.25	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000457.1	0.24	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001833.1	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001758.1	0.23	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001135.1	0.23	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.23	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001166.1	0.23	NRP	HC-toxin	Alternaria jesenskae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001825.1	0.66	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001133.1	0.64	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0000342.1	0.59	NRP	enniatin	Fusarium equiseti
BGC0001873.1	0.58	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000457.1	0.58	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001833.1	0.57	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001758.1	0.56	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001135.1	0.56	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.56	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001166.1	0.56	NRP	HC-toxin	Alternaria jesenskae

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 13632 - 37155:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg88_26

Search NORINE for peptide: strict or relaxed

AMP-binding (467..889): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

NZ_HG426843.1 - Region 1 - NRPS-like,thiopeptide

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Location: 1 - 13,062 nt. (total: 13,062 nt) Show pHMM detection rules used

Region on contig edge.

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Thiopeptides

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001168.1	0.64	NRP	livipeptin	Streptomyces lividans 1326
BGC0001900.1	0.63	NRP	fragin	Burkholderia cenocepacia H111
BGC0001516.1	0.47	NRP	aspergillic acid	Aspergillus flavus NRRL3357
BGC0001599.1	0.39	NRP	fragin	Burkholderia cenocepacia H111
BGC0001844.1	0.37	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758.1	0.37	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.37	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001132.1	0.36	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001641.1	0.36	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001479.1	0.36	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001168.1	0.65	NRP	livipeptin	Streptomyces lividans 1326
BGC0001900.1	0.65	NRP	fragin	Burkholderia cenocepacia H111
BGC0001516.1	0.57	NRP	aspergillic acid	Aspergillus flavus NRRL3357
BGC0001599.1	0.52	NRP	fragin	Burkholderia cenocepacia H111
BGC0001844.1	0.50	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758.1	0.50	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.50	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001132.1	0.50	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001641.1	0.50	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001479.1	0.50	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102

Similar known gene clusters

No matches found.

Thiopeptide predictions

No core peptides found.

Module view

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Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Thiopeptides

Predicted core structure(s)

For candidate cluster 1, location 0 - 13062:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg97_7

Search NORINE for peptide: strict or relaxed

AMP-binding (34..426): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGgiFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 80% (moderate)

Core peptide predictions

No core peptides found.

NZ_HG426848.1 - Region 1 - T1PKS

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Location: 1 - 16,906 nt. (total: 16,906 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

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NRPS/PKS modules

Pfam domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001400.1	0.20	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001273.1	0.20	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001244.1	0.20	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001275.1	0.20	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001276.1	0.20	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001124.1	0.19	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0001254.1	0.18	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0001252.1	0.18	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0001265.1	0.17	Polyketide	melanin	Bipolaris oryzae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001400.1	0.53	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001273.1	0.53	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001244.1	0.52	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001275.1	0.52	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001276.1	0.52	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001124.1	0.51	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0001254.1	0.50	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0001252.1	0.50	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0001265.1	0.49	Polyketide	melanin	Bipolaris oryzae

Similar known gene clusters

No matches found.

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Detailed Pfam domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 16906:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg101_2

PKS_AT (520..795): mmal

ATSignature: (unknown)

No matches above 50%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 65.6
Methoxymalonyl-CoA: 63.9
Malonyl-CoA: 52.8
fatty_acid: 30.6
Propionyl-CoA: 29.8
Ethylmalonyl-CoA: 23.6
trans-1,2-CPDA: 20.1
CHC-CoA: 18.6
Isobutyryl-CoA: 18.2
3-Methylbutyryl-CoA: 15.8
Acetyl-CoA: 13.5
Benzoyl-CoA: 12.1
2-Methylbutyryl-CoA: 9.5
inactive: 0.0

NZ_HG426849.1 - Region 1 - NRPS

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Location: 7,565 - 57,757 nt. (total: 50,193 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

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Select a gene to view the details available for it

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NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001135.1	0.32	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001128.1	0.32	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1	0.32	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001132.1	0.30	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001758.1	0.30	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001844.1	0.29	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001166.1	0.28	NRP	HC-toxin	Alternaria jesenskae
BGC0001131.1	0.28	NRP	ambactin	Xenorhabdus miraniensis
BGC0001825.1	0.27	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001641.1	0.27	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001135.1	0.65	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001128.1	0.65	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1	0.65	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001132.1	0.64	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001758.1	0.63	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001844.1	0.63	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001166.1	0.61	NRP	HC-toxin	Alternaria jesenskae
BGC0001131.1	0.61	NRP	ambactin	Xenorhabdus miraniensis
BGC0001825.1	0.60	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001641.1	0.60	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 7564 - 57757:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - ala - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg102_18

Search NORINE for peptide: strict or relaxed

AMP-binding (490..885): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWLIGAIcK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 90% (moderate)

AMP-binding (1572..1969): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

AMP-binding (2639..3053): X

NRPSPredictor2: orn, lys, arg

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiSnIGAVtK
Nearest Stachelhaus code:: trp
Stachelhaus code match:: 70% (weak)

NZ_HG426861.1 - Region 1 - NRPS-like,betalactone

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Location: 1 - 26,525 nt. (total: 26,525 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

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Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.64	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.62	NRP	indigoidine	Streptomyces chromofuscus
BGC0000900.1	0.54	Other	ferrichrome	Aspergillus oryzae
BGC0000921.1	0.49	Other (Shikimate-derived), Polyketide, NRP	promysalin	Pseudomonas putida
BGC0000876.1	0.48	Other	neopolyoxin C	Streptomyces tendae
BGC0000979.1	0.48	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.48	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0001545.1	0.47	NRP	chrysogine	Fusarium graminearum PH-1
BGC0001859.1	0.46	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0001561.1	0.45	NRP	curacomycin	Streptomyces curacoi

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.65	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.65	NRP	indigoidine	Streptomyces chromofuscus
BGC0000900.1	0.60	Other	ferrichrome	Aspergillus oryzae
BGC0000921.1	0.58	Other (Shikimate-derived), Polyketide, NRP	promysalin	Pseudomonas putida
BGC0000876.1	0.57	Other	neopolyoxin C	Streptomyces tendae
BGC0000979.1	0.57	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.57	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0001545.1	0.57	NRP	chrysogine	Fusarium graminearum PH-1
BGC0001859.1	0.56	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0001561.1	0.55	NRP	curacomycin	Streptomyces curacoi

Similar known gene clusters

No matches found.

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 26525:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg108_5

Search NORINE for peptide: strict or relaxed

AMP-binding (15..406): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DALWLGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

ctg108_13

Search NORINE for peptide: strict or relaxed

AMP-binding (19..394): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GIiyVGifaK
Nearest Stachelhaus code:: tcl
Stachelhaus code match:: 50% (weak)

NZ_HG426875.1 - Region 1 - CDPS,NRPS-like,T1PKS

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Location: 1 - 28,089 nt. (total: 28,089 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
CDPS: (CDPS or cycdipepsynth)

Legend:

core biosynthetic genes

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Pfam domains

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Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001050.1	0.55	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000389.1	0.54	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000457.1	0.53	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001873.1	0.50	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0001161.1	0.48	Polyketide	1-heptadecene	Moorea bouillonii PNG
BGC0001162.1	0.48	Polyketide	1-heptadecene	Moorea producens JHB
BGC0001261.1	0.47	NRP	AM-toxin	Alternaria alternata
BGC0001573.1	0.47	Alkaloid	dihydrolysergic acid	Claviceps africana
BGC0001149.1	0.47	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001187.1	0.46	NRP, Polyketide	xenolozoyenone	Glarea lozoyensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001050.1	0.61	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000389.1	0.60	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000457.1	0.60	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001873.1	0.58	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0001161.1	0.58	Polyketide	1-heptadecene	Moorea bouillonii PNG
BGC0001162.1	0.57	Polyketide	1-heptadecene	Moorea producens JHB
BGC0001261.1	0.57	NRP	AM-toxin	Alternaria alternata
BGC0001573.1	0.57	Alkaloid	dihydrolysergic acid	Claviceps africana
BGC0001149.1	0.57	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001187.1	0.56	NRP, Polyketide	xenolozoyenone	Glarea lozoyensis

Similar known gene clusters

No matches found.

Module view

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Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 28089:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (X - mal) + (asn)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 16041 - 28089:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg118_2

Search NORINE for peptide: strict or relaxed

AMP-binding (482..917): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DATKVGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

ctg118_7

Search NORINE for peptide: strict or relaxed

AMP-binding (1219..1643): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiedLGAItK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 60% (weak)

ctg118_8

Search NORINE for peptide: strict or relaxed

AMP-binding (55..454): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: sfFFfaGPcK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 50% (weak)

PKS_AT (1249..1552): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 66.7%; 2-Rhyd-Malonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 83.4
inactive: 44.2
Methylmalonyl-CoA: 25.2
Methoxymalonyl-CoA: 24.4
Propionyl-CoA: 12.9
Isobutyryl-CoA: 10.2
fatty_acid: 9.5
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

NZ_HG426883.1 - Region 1 - NRPS,T1PKS

Download region GenBank file

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Location: 1 - 61,207 nt. (total: 61,207 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

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other genes

resistance

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Gene details

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NRPS/PKS domains

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NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001050.1	0.79	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000427.1	0.75	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001132.1	0.70	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000979.1	0.69	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.69	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0001434.1	0.69	NRP	nematophin	Xenorhabdus budapestensis
BGC0001698.1	0.69	NRP	nevaltophin A, nevaltophin B, nevaltophin C, nevaltophin D	Xenorhabdus budapestensis
BGC0000375.1	0.69	NRP	indigoidine	Streptomyces chromofuscus
BGC0000457.1	0.67	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001128.1	0.67	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001050.1	0.71	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000427.1	0.70	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000979.1	0.69	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.69	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0001434.1	0.69	NRP	nematophin	Xenorhabdus budapestensis
BGC0001698.1	0.69	NRP	nevaltophin A, nevaltophin B, nevaltophin C, nevaltophin D	Xenorhabdus budapestensis
BGC0001132.1	0.68	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000457.1	0.68	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000375.1	0.68	NRP	indigoidine	Streptomyces chromofuscus
BGC0001128.1	0.67	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters

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Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 61207:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (asn) + (X) + (pk) + (ser) + (ser) + (leu - lys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg125_7

Search NORINE for peptide: strict or relaxed

AMP-binding (324..678): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DylFyGVViK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 60% (weak)

AMP-binding (1332..1713): lys

NRPSPredictor2: lys

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: glu, gln
Single AA prediction:: lys

Stachelhaus prediction details:

Stachelhaus sequence:: DgESIGSiaK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 70% (weak)

ctg125_9

Search NORINE for peptide: strict or relaxed

AMP-binding (32..450): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

AMP-binding (1141..1454): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg125_11

PKS_AT (540..837): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 34.0
Malonyl-CoA: 29.4
Methylmalonyl-CoA: 23.5
inactive: 16.3
Propionyl-CoA: 11.3
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg125_12

Search NORINE for peptide: strict or relaxed

AMP-binding (490..877): X

NRPSPredictor2: asp, asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DpenIGhVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 60% (weak)

ctg125_13

PKS_AT (12..294): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 62.6
Methylmalonyl-CoA: 34.4
Methoxymalonyl-CoA: 32.4
inactive: 29.0
Propionyl-CoA: 24.2
2-Methylbutyryl-CoA: 16.4
CHC-CoA: 13.0
fatty_acid: 11.0
Ethylmalonyl-CoA: 10.5
Benzoyl-CoA: 10.1
Isobutyryl-CoA: 9.4
trans-1,2-CPDA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ctg125_14

Search NORINE for peptide: strict or relaxed

AMP-binding (477..885): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

ctg125_15

Search NORINE for peptide: strict or relaxed

AMP-binding (12..433): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHySLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 90% (moderate)

NZ_HG426887.1 - Region 1 - ladderane

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Location: 1 - 40,789 nt. (total: 40,789 nt) Show pHMM detection rules used

Region on contig edge.

ladderane: ladderane

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000858.1	0.23	Other	ectoine	Methylobacter marinus
BGC0000857.1	0.23	Other	ectoine	Methylophaga alcalica
BGC0000854.1	0.23	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000859.1	0.23	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000855.1	0.23	Other	ectoine	Methylomicrobium kenyense
BGC0000856.1	0.23	Other	ectoine	Methylophaga thalassica
BGC0000906.1	0.21	Other	heme D1	Heliophilum fasciatum
BGC0000905.1	0.21	Other	heme D1	Heliobacillus mobilis
BGC0001591.1	0.18	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.18	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000858.1	0.57	Other	ectoine	Methylobacter marinus
BGC0000857.1	0.56	Other	ectoine	Methylophaga alcalica
BGC0000854.1	0.56	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000859.1	0.56	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000855.1	0.56	Other	ectoine	Methylomicrobium kenyense
BGC0000856.1	0.56	Other	ectoine	Methylophaga thalassica
BGC0000906.1	0.53	Other	heme D1	Heliophilum fasciatum
BGC0000905.1	0.53	Other	heme D1	Heliobacillus mobilis
BGC0001591.1	0.50	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.50	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_HG426895.1 - Region 1 - NRPS-like

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Location: 1 - 15,225 nt. (total: 15,225 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.29	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000900.1	0.27	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.27	NRP	dimethylcoprogen	Alternaria alternata
BGC0000375.1	0.26	NRP	indigoidine	Streptomyces chromofuscus
BGC0001479.1	0.25	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001132.1	0.22	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001135.1	0.21	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001128.1	0.21	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001825.1	0.21	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001517.1	0.20	NRP	asperphenamate	Aspergillus terreus NIH2624

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.62	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000900.1	0.61	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.61	NRP	dimethylcoprogen	Alternaria alternata
BGC0000375.1	0.60	NRP	indigoidine	Streptomyces chromofuscus
BGC0001479.1	0.58	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001132.1	0.54	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001135.1	0.54	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001128.1	0.54	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001825.1	0.53	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001517.1	0.53	NRP	asperphenamate	Aspergillus terreus NIH2624

Similar known gene clusters

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 15225:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg134_12

Search NORINE for peptide: strict or relaxed

AMP-binding (53..470): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLIEK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

NZ_HG426914.1 - Region 1 - PpyS-KS

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Location: 233 - 20,729 nt. (total: 20,497 nt) Show pHMM detection rules used

Region on contig edge.

PpyS-KS: PpyS

Legend:

core biosynthetic genes

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000386.1	0.22	NRP	malleobactin A, malleobactin B, malleobactin C, malleobactin D	Burkholderia thailandensis E264
BGC0001285.1	0.19	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0000896.1	0.14	Other	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0000843.1	0.11	Other (Non-NRP beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate	Streptomyces clavuligerus ATCC 27064
BGC0000943.1	0.11	Other	staphylobactin	Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000469.1	0.09	RiPP	bottromycin A2	Streptomyces sp. BC16019
BGC0000653.1	0.09	Terpene	pentalenolactone	Streptomyces arenae
BGC0001790.1	0.09	NRP	sulfazecin	Pseudomonas acidophila
BGC0001942.1	0.09	NRP, Polyketide	malonomycin	Streptomyces rimosus subsp. paromomycinus
BGC0001671.1	0.08	NRP	monobactam	Agrobacterium tumefaciens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000386.1	0.54	NRP	malleobactin A, malleobactin B, malleobactin C, malleobactin D	Burkholderia thailandensis E264
BGC0001285.1	0.51	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0000896.1	0.43	Other	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0000843.1	0.38	Other (Non-NRP beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate	Streptomyces clavuligerus ATCC 27064
BGC0000943.1	0.37	Other	staphylobactin	Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000469.1	0.34	RiPP	bottromycin A2	Streptomyces sp. BC16019
BGC0000653.1	0.33	Terpene	pentalenolactone	Streptomyces arenae
BGC0001790.1	0.33	NRP	sulfazecin	Pseudomonas acidophila
BGC0001942.1	0.32	NRP, Polyketide	malonomycin	Streptomyces rimosus subsp. paromomycinus
BGC0001671.1	0.30	NRP	monobactam	Agrobacterium tumefaciens

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_HG426925.1 - Region 1 - NRPS

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Location: 47,089 - 90,499 nt. (total: 43,411 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001778.1	0.29	Other	showdomycin	Streptomyces showdoensis
BGC0000427.1	0.22	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001758.1	0.22	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001132.1	0.22	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.21	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000457.1	0.21	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001131.1	0.21	NRP	ambactin	Xenorhabdus miraniensis
BGC0000375.1	0.21	NRP	indigoidine	Streptomyces chromofuscus
BGC0001825.1	0.21	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001641.1	0.21	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001778.1	0.63	Other	showdomycin	Streptomyces showdoensis
BGC0000427.1	0.55	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001758.1	0.55	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001132.1	0.55	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.54	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000457.1	0.54	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001131.1	0.54	NRP	ambactin	Xenorhabdus miraniensis
BGC0000375.1	0.53	NRP	indigoidine	Streptomyces chromofuscus
BGC0001825.1	0.53	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001641.1	0.53	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 47088 - 90499:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg155_55

Search NORINE for peptide: strict or relaxed

AMP-binding (534..937): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

NZ_HG426926.1 - Region 1 - NRPS

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Location: 63 - 76,779 nt. (total: 76,717 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

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regulatory genes

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Gene details

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Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.65	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001185.1	0.55	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001825.1	0.54	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001824.1	0.52	NRP	xefoampeptides A-G	Xenorhabdus beddingii
BGC0000401.1	0.50	NRP	paenibactin	Paenibacillus elgii B69
BGC0001149.1	0.50	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001833.1	0.49	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001132.1	0.49	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001131.1	0.47	NRP	ambactin	Xenorhabdus miraniensis
BGC0000417.1	0.46	NRP	rhodochelin	Rhodococcus jostii RHA1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001185.1	0.69	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0000410.1	0.67	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001615.1	0.66	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000457.1	0.64	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001824.1	0.64	NRP	xefoampeptides A-G	Xenorhabdus beddingii
BGC0001825.1	0.64	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000426.1	0.64	NRP	sevadicin	Paenibacillus larvae
BGC0001149.1	0.62	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001671.1	0.62	NRP	monobactam	Agrobacterium tumefaciens
BGC0001790.1	0.62	NRP	sulfazecin	Pseudomonas acidophila

Similar known gene clusters

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 62 - 76779:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-phe - leu - cys) + (D-X - ser)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 62 - 34736:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - ser)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 25397 - 76779:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-phe - leu - cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg156_8

Search NORINE for peptide: strict or relaxed

AMP-binding (483..894): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DsWdmGyIDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 60% (weak)

AMP-binding (2024..2426): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg156_13

Search NORINE for peptide: strict or relaxed

AMP-binding (36..438): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PMPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

ctg156_33

Search NORINE for peptide: strict or relaxed

AMP-binding (447..849): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAfTLGAvCK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 80% (moderate)

AMP-binding (1929..2329): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAmmAGCVcK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 70% (weak)

AMP-binding (2987..3384): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSgvWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 80% (moderate)

NZ_HG426951.1 - Region 1 - NRPS,NRPS-like,T1PKS

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Location: 1 - 59,356 nt. (total: 59,356 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: cds(Condensation and (AMP-binding or A-OX))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001050.1	1.11	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0001054.1	1.07	NRP, Polyketide	xenocoumacin 1, xenocoumacin II	Xenorhabdus nematophila ATCC 19061
BGC0000979.1	1.05	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	1.05	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0000427.1	1.01	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.99	NRP	indigoidine	Streptomyces chromofuscus
BGC0000900.1	0.93	Other	ferrichrome	Aspergillus oryzae
BGC0001909.1	0.92	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000348.1	0.92	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001249.1	0.92	NRP	dimethylcoprogen	Alternaria alternata

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001054.1	0.74	NRP, Polyketide	xenocoumacin 1, xenocoumacin II	Xenorhabdus nematophila ATCC 19061
BGC0001050.1	0.70	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000979.1	0.69	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.69	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0000427.1	0.67	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.66	NRP	indigoidine	Streptomyces chromofuscus
BGC0000900.1	0.64	Other	ferrichrome	Aspergillus oryzae
BGC0001909.1	0.64	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000348.1	0.64	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001249.1	0.64	NRP	dimethylcoprogen	Alternaria alternata

Similar known gene clusters

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 59356:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal - mal) + (asn) + (ohmal) + (asn) + (glu) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg181_2

PKS_AT (451..743): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 138.4
inactive: 86.2
Methoxymalonyl-CoA: 45.7
Methylmalonyl-CoA: 41.9
Propionyl-CoA: 21.3
2-Methylbutyryl-CoA: 20.5
Isobutyryl-CoA: 12.6
fatty_acid: 10.5
Benzoyl-CoA: 9.9
CHC-CoA: 9.3
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ctg181_3

Search NORINE for peptide: strict or relaxed

AMP-binding (244..643): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAQDmGaVqK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 70% (weak)

ctg181_5

Search NORINE for peptide: strict or relaxed

AMP-binding (459..840): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

ctg181_8

PKS_AT (524..812): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 96.6
Methoxymalonyl-CoA: 65.1
inactive: 55.0
Methylmalonyl-CoA: 52.6
Propionyl-CoA: 29.4
2-Methylbutyryl-CoA: 19.9
Isobutyryl-CoA: 14.8
Ethylmalonyl-CoA: 13.0
fatty_acid: 8.2
trans-1,2-CPDA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ctg181_9

Search NORINE for peptide: strict or relaxed

AMP-binding (461..854): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

ctg181_12

PKS_AT (1109..1396): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 75.0%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 123.6
inactive: 108.5
Methoxymalonyl-CoA: 51.8
Methylmalonyl-CoA: 44.3
Propionyl-CoA: 32.8
Isobutyryl-CoA: 16.9
Ethylmalonyl-CoA: 16.9
2-Methylbutyryl-CoA: 12.4
fatty_acid: 12.3
CHC-CoA: 11.7
Benzoyl-CoA: 10.8
trans-1,2-CPDA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (2605..2897): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 70.8%; 2-Rhyd-Malonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 120.5
inactive: 82.4
Methoxymalonyl-CoA: 43.4
Methylmalonyl-CoA: 36.7
Propionyl-CoA: 25.8
Isobutyryl-CoA: 19.4
fatty_acid: 18.6
Benzoyl-CoA: 10.9
CHC-CoA: 10.1
2-Methylbutyryl-CoA: 9.8
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0