LOCUS       NZ_LS483377.1           9182 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LS483377.1 Stenotrophomonas maltophilia strain NCTC10258
            chromosome 1, complete sequence.
ACCESSION   NZ_LS483377
VERSION     NZ_LS483377.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:28:20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1177777
            Orig. end    :: 1186959
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..225
                     /locus_tag="ctg1_1069"
                     /transl_table=11
                     /translation="MAIVITLDRMLQERGMTLSELAGRIDITLANLSILKTGKARAIRF
                     STLDAICRELQCTPGDLLGHDPAQAQDAD"
     protocluster    1..9182
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1182360:1183206](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(4584..5429)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..9182
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9182
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     PFAM_domain     19..201
                     /aSDomain="HTH_26"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13443.8"
                     /description="Cro/C1-type HTH DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1069_0001"
                     /evalue="2.30E-20"
                     /label="ctg1_1069"
                     /locus_tag="ctg1_1069"
                     /protein_end="67"
                     /protein_start="6"
                     /score="72.9"
                     /tool="antismash"
                     /translation="LDRMLQERGMTLSELAGRIDITLANLSILKTGKARAIRFSTLDAI
                     CRELQCTPGDLLGHDP"
     CDS             269..1807
                     /gene_functions="other (smcogs) SMCOG1273:hypothetical
                     protein (Score: 308.6; E-value: 1.2e-93)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1070"
                     /transl_table=11
                     /translation="MEWLADPSIWMGLATLVVLEIVLGIDNLVFIAILADKLPPHQRDR
                     ARVIGLALALLMRLVLLAALAWIMKLTEPLLTLFDHSFSGRDLILLGGGLFLLFKGTME
                     LHERLEGREHHEDGKKVYASFAMVVAQIVVLDAVFSLDSVITAVGMVDNLGVMYAAVTI
                     AMALMLLASRPLTRFVNKHPTVVVLCLGFLLMIGFSLVAEGLGYKIPKGYLYAAIAFSI
                     LVEAFNQWVRFNRERNERRQPFRQRTADAVLRMLGARPANGHDDESADEHVDAEERLQP
                     AEHEMIRSVLGLADRPVSSVMTVRADVQWIDLARGQEDVVARLVASPHTRLLVGDGDLD
                     SLRGVVQSRDLLADLLQGRPLQLEGNLREPQYVLSSASALQALELIRQHPVPLAVAVDE
                     YGSVEGLVTANDLLAAIAGDLVDTQDERYGVVAQGEDQWEADGALTLDDLQRLAGVSLP
                     RSADYMTISGLVLERLGRLPDIGDAVEIADVRITVLAMEKRRIARLRVERLGHP"
     PFAM_domain     311..877
                     /aSDomain="TerC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03741.18"
                     /description="Integral membrane protein TerC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1070_0002"
                     /evalue="2.30E-48"
                     /label="ctg1_1070"
                     /locus_tag="ctg1_1070"
                     /protein_end="203"
                     /protein_start="14"
                     /score="164.4"
                     /tool="antismash"
                     /translation="TLVVLEIVLGIDNLVFIAILADKLPPHQRDRARVIGLALALLMRL
                     VLLAALAWIMKLTEPLLTLFDHSFSGRDLILLGGGLFLLFKGTMELHERLEGREHHEDG
                     KKVYASFAMVVAQIVVLDAVFSLDSVITAVGMVDNLGVMYAAVTIAMALMLLASRPLTR
                     FVNKHPTVVVLCLGFLLMIGFSLVAE"
     PFAM_domain     1370..1519
                     /aSDomain="CBS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00571.30"
                     /description="CBS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1070_0003"
                     /evalue="1.50E-04"
                     /label="ctg1_1070"
                     /locus_tag="ctg1_1070"
                     /protein_end="417"
                     /protein_start="367"
                     /score="22.2"
                     /tool="antismash"
                     /translation="REPQYVLSSASALQALELIRQHPVPLAVAVDEYGSVEGLVTANDL
                     LAAIA"
     PFAM_domain     1562..1795
                     /aSDomain="CorC_HlyC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03471.19"
                     /description="Transporter associated domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1070_0004"
                     /evalue="6.10E-22"
                     /label="ctg1_1070"
                     /locus_tag="ctg1_1070"
                     /protein_end="509"
                     /protein_start="431"
                     /score="77.5"
                     /tool="antismash"
                     /translation="AQGEDQWEADGALTLDDLQRLAGVSLPRSADYMTISGLVLERLGR
                     LPDIGDAVEIADVRITVLAMEKRRIARLRVERL"
     CDS             1942..3078
                     /locus_tag="ctg1_1071"
                     /transl_table=11
                     /translation="MVAVLSTIGLLMGLYVAWRLFWPLRMPIWMKVVLSLLLVGVAVQL
                     RIVATFWGTMASPEIPKLAIAVLATGSTAVLLLALMMLVLDAGLLLSRLLRWPRIASVL
                     RASKLRPLASLLALLVSGYGISQGMAVPQPRQIDVAIKDLPAAFDGYRVLQLTDIHASR
                     LLTGDWVRRVVDESNALTPDLIVITGDLIDGSVEARRDDARPLADLRAPDGVVAITGNH
                     EYYAQYQAWMQAFRALHLQVLENSHLQVRRGDAALTIAGVTDPVAARYGLPLPDLETAL
                     AGADPSAPVILLDHRPRNAREAAARGVKLQLSGHTHGGQIFGMDQLVKRANGGYVSGRY
                     DVDGMTLYVSNGAGLWAGFPARIGVPSEITLITLRRAP"
     PFAM_domain     2395..2892
                     /aSDomain="Metallophos"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00149.30"
                     /description="Calcineurin-like phosphoesterase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1071_0005"
                     /evalue="2.90E-11"
                     /label="ctg1_1071"
                     /locus_tag="ctg1_1071"
                     /protein_end="317"
                     /protein_start="151"
                     /score="44.4"
                     /tool="antismash"
                     /translation="RVLQLTDIHASRLLTGDWVRRVVDESNALTPDLIVITGDLIDGSV
                     EARRDDARPLADLRAPDGVVAITGNHEYYAQYQAWMQAFRALHLQVLENSHLQVRRGDA
                     ALTIAGVTDPVAARYGLPLPDLETALAGADPSAPVILLDHRPRNAREAAARGVKLQLSG
                     HTH"
     CDS             complement(3135..3773)
                     /locus_tag="ctg1_1072"
                     /transl_table=11
                     /translation="MAPSNTSFLHGWRLFVAVAVVLIAFALAAFALYPDAAEGSRAAIR
                     VTARTSFLLFLAAFTASSFASLLPGPFTRFLLRERRIIGLSFAFSHLLHAVAITSFGVL
                     NPAFWPARSALANLPGTVGYIAILALAITSHRGLARRMGPTAWRRLHVTGMWIIAAVFT
                     YSYFKRVPGNFWYAVPSALLFTAFVVRWIAKRAQALRRSAHVRPPLRAA"
     PFAM_domain     complement(3294..3623)
                     /aSDomain="Ferric_reduct"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01794.21"
                     /description="Ferric reductase like transmembrane
                     component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1072_0006"
                     /evalue="1.80E-08"
                     /label="ctg1_1072"
                     /locus_tag="ctg1_1072"
                     /protein_end="160"
                     /protein_start="50"
                     /score="34.6"
                     /tool="antismash"
                     /translation="SFLLFLAAFTASSFASLLPGPFTRFLLRERRIIGLSFAFSHLLHA
                     VAITSFGVLNPAFWPARSALANLPGTVGYIAILALAITSHRGLARRMGPTAWRRLHVTG
                     MWIIAA"
     CDS             complement(3857..4591)
                     /locus_tag="ctg1_1073"
                     /transl_table=11
                     /translation="MAESLATLQRRWADHVRAPAKTAPDGIEARRMAVYRRLCIDSLDT
                     LLAGSLPRLKSQLGDACWRNTVEHYYARHACRTPLFPQIAGEFAAWLAVQDTLALPGWA
                     AELAHYESTQQSLHIEARDGGRPLQRAPVGNDVLAISPLVRVLGYQWPVHEDGALEPVL
                     STAPTLLVIQRLADFSLLTEELSPLAYALLSVFGDDSASVDEALQLLSETHGVAADALR
                     MACVPVLGELCAAGVLVALPAF"
     PFAM_domain     complement(4316..4570)
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1073_0007"
                     /evalue="1.00E-18"
                     /label="ctg1_1073"
                     /locus_tag="ctg1_1073"
                     /protein_end="92"
                     /protein_start="7"
                     /score="67.4"
                     /tool="antismash"
                     /translation="LQRRWADHVRAPAKTAPDGIEARRMAVYRRLCIDSLDTLLAGSLP
                     RLKSQLGDACWRNTVEHYYARHACRTPLFPQIAGEFAAWL"
     CDS             complement(4584..5429)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1074"
                     /sec_met_domain="DUF692 (E-value: 2.9e-119, bitscore:
                     395.1, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLPLPAHAAGLGLRRGLIDELLAMPAGAIDFLEVSPDNWIGVGG
                     AHGAALRQLSERHPLTCHGLSLSLGGPDPLDRTLLAQTRAFLDLHQVQLYSEHLSYCAA
                     GGHVYDLLPLPFTAEAVHHVAGRIAQVQDMLGRRIAVENISYYAVAGADMSEIDFINAV
                     LAEADCDLLLDVNNVFVNACNNGYDAFEFLARVPAHRVASLHVAGHFDEDDGFKIDTHG
                     APVKGVVWALLREAYARVGVRPTLLERDFNFPPLAELLAEVGQIRQAQAEARWPEVAHG
                     "
     PFAM_domain     complement(4620..5402)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1074_0008"
                     /evalue="4.70E-102"
                     /label="ctg1_1074"
                     /locus_tag="ctg1_1074"
                     /protein_end="270"
                     /protein_start="9"
                     /score="340.8"
                     /tool="antismash"
                     /translation="AGLGLRRGLIDELLAMPAGAIDFLEVSPDNWIGVGGAHGAALRQL
                     SERHPLTCHGLSLSLGGPDPLDRTLLAQTRAFLDLHQVQLYSEHLSYCAAGGHVYDLLP
                     LPFTAEAVHHVAGRIAQVQDMLGRRIAVENISYYAVAGADMSEIDFINAVLAEADCDLL
                     LDVNNVFVNACNNGYDAFEFLARVPAHRVASLHVAGHFDEDDGFKIDTHGAPVKGVVWA
                     LLREAYARVGVRPTLLERDFNFPPLAELLAEVGQIRQAQ"
     CDS             complement(5486..5962)
                     /locus_tag="ctg1_1075"
                     /transl_table=11
                     /translation="MSISTRNTPSSRLPRIGAIGIALAGGLLLAGQAAAIQPLAISAVA
                     MSATAEGKCGEGKCGANKATTGKPAGKAKVAEGQCGEGKCGDASFARTDRDHDGKVSRA
                     EFNAVAAKRAAEFDRIDTDHDGYISEQEAHDYLRSVYTANGKPMPKGLFSRVAD"
     PFAM_domain     complement(5567..5614)
                     /aSDomain="EF-hand_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13202.8"
                     /description="EF hand"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1075_0010"
                     /evalue="7.10E-04"
                     /label="ctg1_1075"
                     /locus_tag="ctg1_1075"
                     /protein_end="132"
                     /protein_start="116"
                     /score="19.0"
                     /tool="antismash"
                     /translation="FDRIDTDHDGYISEQE"
     PFAM_domain     complement(5636..5695)
                     /aSDomain="EF-hand_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13202.8"
                     /description="EF hand"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1075_0009"
                     /evalue="2.10E-03"
                     /label="ctg1_1075"
                     /locus_tag="ctg1_1075"
                     /protein_end="109"
                     /protein_start="89"
                     /score="17.5"
                     /tool="antismash"
                     /translation="FARTDRDHDGKVSRAEFNAV"
     CDS             complement(6058..6702)
                     /locus_tag="ctg1_1076"
                     /transl_table=11
                     /translation="MISTASSVYTPRLDAVGRWLSPLALRTLLAWEFFESGREKLGGQN
                     WFADLEGRFPFPFSALPASLNWQLATWLELVGAVMLLLGLATRSVAYVFWILTIVAIAA
                     VHWPDQWNGLGELWQGYAITDQGYGNFKLPLLFLAMLLPLILNGGGALSVDRLLAGPQH
                     AAVGNDGLGWGVSLIALLLPVAALLPGIGFGGALLGGVLLLGYLLRRRRAT"
     PFAM_domain     complement(6382..6639)
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1076_0011"
                     /evalue="7.20E-17"
                     /label="ctg1_1076"
                     /locus_tag="ctg1_1076"
                     /protein_end="107"
                     /protein_start="21"
                     /score="61.9"
                     /tool="antismash"
                     /translation="PLALRTLLAWEFFESGREKLGGQNWFADLEGRFPFPFSALPASLN
                     WQLATWLELVGAVMLLLGLATRSVAYVFWILTIVAIAAVHW"
     CDS             7044..7835
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1077"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.4e-15, bitscore:
                     54.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTSLLAAALALAAAAPAFAAQVDTAAPPTVILVHGAFADGSSW
                     SKVISTLHDWKLPAVAVQNPLTSLADDVAATRRAIAAAPGKVVLVGHSWGGTVITEAGN
                     DPKVQALVYVAAFAPDAGQSSAQQGEGFPVGPGLARLQERDGYLTLPADAIAQDFAPDV
                     MKKSAALLYSTQVPLKASALGEVVNVAAWRSKPSWYVLSRDDRMLSPQLQAATAKRIGA
                     QLQSIGSSHVSLLSHPAQVADSILEAAGVKPAELPLAEQGG"
     PFAM_domain     7137..7772
                     /aSDomain="Abhydrolase_6"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12697.9"
                     /description="Alpha/beta hydrolase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1077_0012"
                     /evalue="1.10E-15"
                     /label="ctg1_1077"
                     /locus_tag="ctg1_1077"
                     /protein_end="243"
                     /protein_start="31"
                     /score="59.0"
                     /tool="antismash"
                     /translation="VILVHGAFADGSSWSKVISTLHDWKLPAVAVQNPLTSLADDVAAT
                     RRAIAAAPGKVVLVGHSWGGTVITEAGNDPKVQALVYVAAFAPDAGQSSAQQGEGFPVG
                     PGLARLQERDGYLTLPADAIAQDFAPDVMKKSAALLYSTQVPLKASALGEVVNVAAWRS
                     KPSWYVLSRDDRMLSPQLQAATAKRIGAQLQSIGSSHVSLLSHPAQVAD"
     CDS             7839..8384
                     /gene_functions="other (smcogs) SMCOG1241:lipoprotein dsbF
                     (Score: 110.9; E-value: 9.3e-34)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1078"
                     /transl_table=11
                     /translation="MAALRGYALPLLLALLGGAALLLAWPGADAGAQPLDAEPMAGFDG
                     GGPWHNSPPLTLKQLRGQVVLVEFWTYTCRNCLNVAPHVHQWHARYASQGLRVIGVHTP
                     EFAYEGLPGNVRKAIARLDITWPVVQDNQYRIWNAWRNRFWPALYLLDRQGRVVYRHYG
                     EGDYARTESEIQRLLANP"
     PFAM_domain     7998..8315
                     /aSDomain="AhpC-TSA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00578.23"
                     /description="AhpC/TSA family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1078_0013"
                     /evalue="1.10E-09"
                     /label="ctg1_1078"
                     /locus_tag="ctg1_1078"
                     /protein_end="159"
                     /protein_start="53"
                     /score="38.3"
                     /tool="antismash"
                     /translation="PLTLKQLRGQVVLVEFWTYTCRNCLNVAPHVHQWHARYASQGLRV
                     IGVHTPEFAYEGLPGNVRKAIARLDITWPVVQDNQYRIWNAWRNRFWPALYLLDRQGRV
                     VY"
     CDS             8442..9182
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 192.2; E-value: 1.6e-58)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1079"
                     /transl_table=11
                     /translation="MNHVPHILVVDDDSEIRQMLADYLQRNGLRVSQADGGRAMRALMD
                     THAVDLVVLDVMMPGEDGLSLCRNLRAGKHRAVPVVLLTARDDETDRIIGLEMGADDYV
                     TKPFSSRELLARINAVIRRTQMLPPNLQVSEAGRQLAFGEWRLDTTARHLLDAQDTAHP
                     LSGAEFRLLRVFLDHANRVLSRDQLLSLTQGRDAELFDRSIDLLVSRVRQRLGDDAREP
                     TYIKTVRSEGYVFSVPVQLLGPDE"
     PFAM_domain     8460..8795
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1079_0014"
                     /evalue="6.40E-30"
                     /label="ctg1_1079"
                     /locus_tag="ctg1_1079"
                     /protein_end="118"
                     /protein_start="6"
                     /score="103.7"
                     /tool="antismash"
                     /translation="ILVVDDDSEIRQMLADYLQRNGLRVSQADGGRAMRALMDTHAVDL
                     VVLDVMMPGEDGLSLCRNLRAGKHRAVPVVLLTARDDETDRIIGLEMGADDYVTKPFSS
                     RELLARIN"
     PFAM_domain     8928..9146
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1079_0015"
                     /evalue="2.00E-19"
                     /label="ctg1_1079"
                     /locus_tag="ctg1_1079"
                     /protein_end="235"
                     /protein_start="162"
                     /score="69.5"
                     /tool="antismash"
                     /translation="PLSGAEFRLLRVFLDHANRVLSRDQLLSLTQGRDAELFDRSIDLL
                     VSRVRQRLGDDAREPTYIKTVRSEGYVF"
ORIGIN
        1 atggcgatcg tcatcaccct ggaccgcatg ctgcaggaac gcggcatgac cctgtccgag
       61 ctggccgggc gcatcgacat caccctggcc aatctgtcga tcctgaagac cggcaaggcg
      121 cgcgccatcc gcttttccac ccttgatgcg atctgccgcg agctgcagtg cacgcccggc
      181 gacctgctcg ggcacgaccc ggcgcaggca caggacgctg actgagcggt cgctcttttc
      241 ccttacctac tgacgaaacg gacctgaaat ggaatggttg gctgacccct cgatctggat
      301 gggccttgca accctggtcg tgctggagat cgttctcggc atcgacaacc tggtgttcat
      361 cgcgatcctt gccgacaagc taccgccgca ccagcgtgac cgcgcgcggg taatcggcct
      421 ggcgctggcc ttgctgatgc ggctggtgct gctggcggcg ttggcgtgga tcatgaaact
      481 gaccgagccg ctgctgacgc tgttcgacca cagcttctcc gggcgtgacc tgatcctgtt
      541 gggcggtggc ctgttcctgc tgttcaaggg caccatggag ctgcacgaac ggctggaagg
      601 ccgcgaacac cacgaggatg gcaagaaggt ctacgccagc ttcgcaatgg tggtggcaca
      661 gatcgtggtg ctcgacgcgg tgttctcgct ggactcggtg atcaccgcgg tgggcatggt
      721 cgacaacctg ggcgtgatgt atgccgccgt gaccatcgcg atggcgctga tgctgttggc
      781 cagcaggccg ctgacgcgct tcgtcaacaa gcatcctacg gtggtggtgc tgtgcctggg
      841 cttcctgctg atgatcggtt tcagcctggt ggccgagggc ctgggctaca agattccgaa
      901 gggttacctg tacgcggcga ttgccttctc gatcctggtc gaggcgttca accagtgggt
      961 gcgtttcaac cgtgagcgca acgaacgccg ccagcccttc cgccagcgca ccgccgacgc
     1021 cgtgctgcgc atgctgggcg cgcgcccggc caatggccac gacgacgaaa gcgcggacga
     1081 acacgtcgat gccgaagagc gcctgcagcc ggcggagcac gagatgatcc gcagcgtgct
     1141 ggggctggcc gatcgcccgg tgtcgagcgt gatgacggtg cgtgccgacg tgcagtggat
     1201 cgacctggcc cgtgggcagg aggatgtggt ggcacgcctg gtggcgtcgc cgcacacccg
     1261 cttgctggtg ggtgatggcg acctggacag cctgcgtggc gtggtgcaga gccgcgacct
     1321 gctggccgac ctgctgcagg gcaggccgct gcagctggaa ggcaacctgc gcgagccgca
     1381 gtacgtgctg tccagtgcca gcgcgctgca ggcgctggaa ctgatccgcc agcacccggt
     1441 gccgttggcg gtggcggtgg acgagtacgg cagcgtggaa ggcctggtga ccgccaacga
     1501 cctgctggcg gccattgccg gtgacctggt cgatacccag gacgagcgct atggcgtggt
     1561 cgcgcagggc gaggaccaat gggaggccga cggtgccctg accctggacg acctgcagcg
     1621 gctggccggc gtatcgctgc cgcgcagtgc cgactacatg accatctccg gcctggtgct
     1681 ggagcgtctg gggcgcctgc cggacatcgg tgacgcggtg gagattgcgg atgttcgcat
     1741 caccgtactg gcgatggaga agcgtcgcat cgcccgcctg cgggtggagc gcctggggca
     1801 tccgtagcgt cgagccatgc gcgatcgggg ttctgtagcg tcgagccatg ctcgacggct
     1861 tcctgggcag ccgagcatgg gcccggctct acacaacacg acccgcagcc gtcaccatgg
     1921 cgggcccgct ttctttcctg gatggttgca gtgctgagta cgatcggttt gttgatgggc
     1981 ctgtatgtgg cctggcgcct gttctggcca ctgcgcatgc ccatctggat gaaggtcgtg
     2041 ctgtcgttgc tgctggtggg cgtggccgtg cagctgcgca tcgtcgccac cttctggggc
     2101 acgatggcct cgccggagat cccgaagctg gccatcgccg ttctggccac cggctccacg
     2161 gcggtactgc tgctcgcctt gatgatgctg gtactggatg ccggcctgct gctttcgcgc
     2221 ctgctgcgtt ggccgcgcat cgcatcggtc ctgcgcgcct cgaagctgcg gccgttggcc
     2281 agcctgctgg cgctgcttgt gagtggctat ggcatcagcc agggcatggc cgtgccccag
     2341 cctcggcaga tcgacgtggc gatcaaggat ctacctgctg cgttcgacgg ctatcgcgtg
     2401 ctgcagctga ccgacatcca tgccagccgc ctgctgaccg gcgactgggt gcgcagggtt
     2461 gtggacgaga gcaacgcact gacaccggac ctgatcgtga tcactggcga tctgatcgac
     2521 ggcagtgtcg aggcccgccg tgacgacgcg cgcccgctcg cggacctgcg ggcgccggac
     2581 ggcgtcgtcg ccatcaccgg caaccacgag tactacgcgc agtaccaggc gtggatgcag
     2641 gcgttccgcg cgctgcacct gcaggtgctg gagaacagcc acctgcaggt gcggcgcggc
     2701 gatgctgcgc tgaccatcgc cggcgtcacc gatccggtgg cggcacgcta tggcctgccg
     2761 ctgccggatc tggaaaccgc gctggccggc gccgatccct ctgcaccggt gatcctgctc
     2821 gatcaccgcc cgcgcaatgc gcgtgaagct gccgcgcgcg gtgtgaagct gcaattgtcc
     2881 gggcataccc acggcgggca gatctttggt atggaccagc tggtgaaacg agccaacggc
     2941 ggctatgtct ccggccgcta cgacgtggac gggatgacac tgtacgtgag caacggtgcg
     3001 ggcctctggg caggtttccc ggcgcgcatc ggtgtgccgt cggagatcac cctgatcacg
     3061 ctgcgccgcg cgccttgacc tgaagtgggg gtcagatccc attcccgcag gtaaaggcat
     3121 ctggcgccag cccctcaggc cgcccgcagc ggcggccgca catgcgcact tcggcgcagc
     3181 gcctgcgccc gcttggcaat ccagcgcacc acgaaggcgg tgaacagcag cgccgacggc
     3241 accgcatacc agaagttgcc cggaacgcgc ttgaagtacg agtaggtaaa caccgccgcg
     3301 atgatccaca tgccggtgac gtgcaggcga cgccaggcgg tgggtcccat gcgccgggcg
     3361 agcccccggt gcgaggtgat ggccagcgcc aggatggcaa tgtagcccac cgtgcccggg
     3421 aggttggcca gcgcggatcg tgctggccag aacgccgggt tgaggacgcc gaaactggtg
     3481 atcgcgactg catgcaacag gtgcgagaac gcgaaggaca ggccgatgat gcgccgttcg
     3541 cgcagcagga agcgggtgaa cggaccgggc agaaggctgg cgaacgacga tgccgtgaac
     3601 gctgccagga acagcaggaa cgatgtgcgc gcagtgaccc ggatcgcggc tcggctgcct
     3661 tcggctgcat cgggatacag ggcgaaggcc gccagcgcga aggcgatcag gaccaccgct
     3721 acggccacga acaggcgcca gccatgcagg aaggacgtgt tggaaggagc catgatgaga
     3781 cctcgaagta gggggacggt agtgccggcc gctggccggt caaggaacgg gtagtgccgg
     3841 ccggtggcca gcaacctcag aaagcaggca atgcaaccag cacgcccgcc gcgcacagct
     3901 cgcccagaac aggcacgcag gccatgcgca atgcgtccgc tgccacgcca tgtgtttcgg
     3961 acagcagctg cagtgcttca tccaccgacg cgctgtcgtc accgaacacc gacagcagcg
     4021 cgtaggccag cggtgacagt tcctcggtca gcaggctgaa atcggcgagg cgctggatca
     4081 ccagcagcgt gggagccgtg ctcaacaccg gctccagcgc cccgtcctca tgtactggcc
     4141 actggtagcc aagcacccgc accaacggcg aaatcgccag cacatcattg cctacgggag
     4201 cccgctgcag cggccgccca ccgtcacgcg cttcaatgtg cagcgactgc tgcgtgctct
     4261 cgtagtgcgc cagttccgct gcccagcccg gcagcgccag cgtgtcctgc accgccagcc
     4321 aggccgcgaa ctcgcccgcg atctgcggga acaacggcgt gcggcaggcg tgcctcgcgt
     4381 agtagtgctc gacggtgttg cgccagcagg catcgcccag ctgcgacttc aaccgcggca
     4441 ggctgccggc cagcagggtg tccaagctgt cgatgcacag gcggcggtag accgccatcc
     4501 gccgcgcctc gatgccatcg ggtgcggtct ttgcaggggc gcgcacatga tcggcccagc
     4561 gccgttgcag ggtagccagc gactcagcca tgggccacct cgggccaacg tgcctcggcc
     4621 tgcgcctggc ggatctgccc gacctcggcc agcaattcgg caagcggggg gaagttgaag
     4681 tcgcgttcga gcagcgtggg gcgcacgccc acccgcgcat aggcctcgcg caacagtgcc
     4741 cagaccacgc ctttcaccgg cgcaccatgg gtatcgatct tgaagccatc gtcttcatcg
     4801 aagtggcccg ctacgtgcag cgaggcgacg cggtgggccg gcacgcgggc caggaattcg
     4861 aaggcgtcgt agccgttgtt gcaggcgttg acgaaaacgt tgttgacgtc cagaagcagg
     4921 tcgcagtcgg cttcggcgag cacggcgttg atgaagtcga tctcgctcat gtccgcgccg
     4981 gcaacggcgt agtaggagat gttctccacg gcgatgcgtc ggcccagcat gtcctgcacc
     5041 tgggcgatgc gaccggcgac atggtgaacg gcctcggcgg tgaacggcag cggcagcagg
     5101 tcgtagacat ggccgccggc ggcgcagtag ctcaggtgtt cgctgtacag ctgcacctgg
     5161 tgcaggtcga ggaaggcacg ggtctgtgcc agcagggtgc ggtccagcgg atcaggacct
     5221 cccagcgaca gcgacaggcc gtggcaggtc aggggatggc gctcgctgag ctggcgcagc
     5281 gcggcgccgt gtgcaccgcc gacgccgatc cagttgtcag gggagacttc gaggaagtcg
     5341 atggcaccgg ccggcatggc cagcagttcg tcgatcagcc cacggcgcag gccaagaccg
     5401 gcggcatggg cgggcagggg cagggacatg gtggatgctc cagggagagg gcgccgcctt
     5461 gaaggcggcg ccgggtgaac gtcgatcaat cggcaacgcg ggagaacagg cccttcggca
     5521 tcggcttgcc gttggcggtg tagacgctgc gcaggtagtc gtgcgcttcc tgctcgctga
     5581 tgtaaccgtc gtggtcggtg tcgatgcggt cgaactcggc ggcgcgcttg gcggccacag
     5641 cgttgaactc ggcacgcgag accttgccgt cgtggtcgcg gtcagtgcgg gcaaacgagg
     5701 cgtcgccgca cttgccttcg ccacactggc cctcggccac cttggccttg ccggcgggct
     5761 tgccggtggt ggccttgttg gccccgcact tgccttcacc gcacttgcct tcggcggtgg
     5821 cgctcatggc caccgcgctg atcgccagcg gttggatcgc ggcggcctgg ccggccagca
     5881 gcaggccacc ggccagggca atgccgatgg caccgatgcg cggcaggcgg gaggaggggg
     5941 tgttcctggt cgagatggac atggtgatga ctccttggga aagcacgcgg ggcgtgcggg
     6001 atggacgccg ccgaggaggc gacggaaagc gaaaggcgcg ggaacagggg aatcagctca
     6061 ggtggcgcgg cggcgacgca gcagatagcc cagcagcagc acgccgccga gcagggcacc
     6121 gccgaagccg atgccgggca gcagcgcggc aaccggcagc agcagggcga tcaggctgac
     6181 gccccagccc aggccgtcat tgccgacagc ggcatgctgt gggccggcca gcagccggtc
     6241 cacgctgagc gcgccaccgc cgttgaggat cagcggcagc aacatggcca ggaacagcag
     6301 tggcagcttg aagttgccgt agccctggtc ggtgatcgcg tagccctgcc agagttcacc
     6361 caggccgttc cattggtcgg gccagtgcac ggcggcgatg gcaacgatgg tgaggatcca
     6421 gaagacgtag gccaccgagc gcgtggccag gccgagcagc agcatcaccg cgcccaccag
     6481 ttccagccag gtcgccagct gccagttcag cgatgcgggc agggcggaga acgggaacgg
     6541 gaagcggcct tccaggtcgg cgaaccagtt ctggccgccc agcttctcgc ggccggattc
     6601 aaagaactcc caggccagca gggtgcgcag cgccaatggc gagagccagc ggccgacggc
     6661 atccaggcgg ggggtataca cggaagaggc ggtgctgatc atggtggtgt cctgcgggcc
     6721 agtggtcgat ggagaccatt ccaggcggcg caggtatcgg caacgtgtgc cgttgcccgg
     6781 ggttttgtca gcgactgtgg tcgcggccgg ggtttcgtac agtcagatac aaagacgatg
     6841 cgttgacgca catcggggcg ttgcgcgccc gcgtgcgggg agcgatattc acccgaaagc
     6901 gcccagccag gaccggcgcg cgaatgtatc ccactgtaga aacccgcctg cgccctacag
     6961 tccggtacaa ctccgcgctg cggagaaaca gcgccgatac accggcaggc ggaaatggcc
     7021 actcccaaca ccggagtgcc cccatgatcc gtacctcctt gctggccgcc gctctcgccc
     7081 ttgccgccgc cgcccctgcc ttcgctgccc aggtcgatac cgctgcaccg cccaccgtca
     7141 tcctggtgca cggcgccttc gccgatggct ccagctggag caaggtcatc agtaccctgc
     7201 atgactggaa gctgccggcg gtggccgtac agaatccgct cacctcgttg gccgacgacg
     7261 tcgccgccac ccgtcgtgcg attgccgctg cgcctggcaa ggtggtgctg gtcggccaca
     7321 gctggggtgg cacggtcatc accgaagcgg gcaatgaccc gaaggtgcag gcgctggtgt
     7381 acgtggcggc gttcgcaccg gatgcagggc aatcttcggc gcaacagggc gaaggtttcc
     7441 cggtcggtcc gggtctggcc cgactgcagg aaagggacgg ctacctgacc ttgccggctg
     7501 atgccatcgc ccaggacttc gcgccggacg tgatgaaaaa atcggccgca ctgctgtaca
     7561 gcacgcaggt cccgttgaag gccagcgcgc tgggcgaagt agtgaacgtt gcggcgtggc
     7621 gcagcaagcc gagctggtac gtgctcagcc gtgacgatcg catgctgtcg ccgcagctgc
     7681 aggccgccac cgcaaagcgc attggcgcgc agctgcaatc gatcggcagc agccatgtgt
     7741 cgctgctttc gcatccggcg caggtggccg acagcatcct ggaagcggcg ggggtgaagc
     7801 cggcggaact gccgctggcc gagcaggggg gctgagcgat ggccgcactg cgagggtacg
     7861 cattgccgct gttgctggcc ctgctgggcg gagcggcgtt gttgctggca tggcccggcg
     7921 cggatgccgg cgcgcaaccg ctcgatgcag aaccgatggc ggggttcgac ggtggcgggc
     7981 cctggcacaa cagcccaccg ctcacactga agcagttgcg ggggcaggtg gtgctggtcg
     8041 agttctggac ctacacctgc cgcaactgcc tcaacgtggc gccgcatgtc caccagtggc
     8101 atgcacgcta cgcgtcgcag ggcctgaggg tgatcggcgt gcatacgccg gagttcgcct
     8161 atgaagggtt gcccggcaac gtgcgcaagg ccatcgcacg gttggacatc acctggccgg
     8221 tggtgcagga caaccagtac cggatctgga acgcctggcg caaccgcttc tggcccgcgc
     8281 tgtacctgct cgaccgtcag gggcgggtgg tctaccgcca ttacggcgag ggcgactacg
     8341 cacgtaccga aagcgagatc cagcgcctgc tggccaaccc ctgagccgcg ctaccatggc
     8401 cgcgcagcgc ggccctgacc tccgtcttca tcgagaacgc aatgaaccac gtaccgcata
     8461 tcctggtcgt cgacgatgac agcgagatcc gccagatgct ggccgattac ctgcagcgca
     8521 acggcctgcg cgtgagccag gccgacggtg gccgggccat gcgcgcgctg atggataccc
     8581 atgccgtgga tctggtggtg ctggacgtga tgatgccggg cgaggacggc ctgagcctgt
     8641 gccgcaacct gcgcgccggc aagcatcgcg cggtgccggt ggtgctgctg accgcccgcg
     8701 acgacgagac cgaccgcatc atcggcctgg aaatgggcgc tgatgactat gtgaccaagc
     8761 ccttctcttc gcgcgaactg ctggcacgca tcaatgcggt gatccgccgc acgcagatgc
     8821 tgccgccgaa tctgcaggtg agcgaagcag gtcgccagct tgccttcggc gagtggcgcc
     8881 tggacaccac cgcacgccat ctgctggatg cgcaggacac cgcgcatccg ctcagtggcg
     8941 ccgagttccg cctgttgcgc gtgttcctcg atcacgccaa tcgggtgctc agccgtgacc
     9001 agctgctcag cctcacccag ggccgcgatg ccgaactgtt cgaccgctcg atcgatctgc
     9061 tggtcagccg cgtgcggcag cgcctgggtg acgacgcacg cgagccgacc tacatcaaga
     9121 ccgtgcgcag cgaaggctat gtgttcagcg tgccggtgca gttgctgggg ccggacgaat
     9181 ga
//
