LOCUS       NC_011312.1            12460 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_011312.1 Aliivibrio salmonicida LFI1238 chromosome 1, complete
            sequence.
ACCESSION   NC_011312
VERSION     NC_011312.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:54:54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 167802
            Orig. end    :: 180262
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12460
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[172802:175262](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7460
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
     cand_cluster    1..12460
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12460
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     CDS             51..1526
                     /locus_tag="ctg1_141"
                     /transl_table=11
                     /translation="VNKLTVSLMIGALLPLNVNANSCKIEGYTIGFFNGVATTKKDAER
                     GRDKIKSTLDITQYNGEKVEYQLFYNDSYIESNGFNVLADFAETFDQRTQELEQKQFDR
                     WEAFWDIVNGKQDSSIIKKISAAFSWFGGFFTDFNSQRSNIIIREFLELLTLSVDSPDT
                     AKTQMQHKLINDSNTWQGKKLIYIAHSQGNLWVNKSYNYVVSQLGYDASNIHVVHIAPA
                     SPTLSPNSDYILSSSDLVINGLNFTGVGSVPPFNTIIAPSSSDIAGHGLIEVYLTHPKS
                     IQKIKSATDKAFASLTKPDMEDVLFSIDYNYTPTFSESHASPEIEFVDNNNNWVKRTDI
                     YSEISYLQRADPNENKYELNPAKDFEPLSFIHNKKDRESQVISIDQCSDIPNNDPFILG
                     EQSNETIRYAWDKVPPNTKVSVTVRDRYGVKLQNDEVSINELRPRGHTYQGIFIDLNAI
                     NPYTKEEKAFIKQQKLETKYELYSDSILFSISS"
     CDS             2098..3645
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 378;
                     E-value: 9.7e-115)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_142"
                     /transl_table=11
                     /translation="MDTKYFEKNANNDTLFNQSSLLSNVDFFDSSSLDHYKEITELGLN
                     TLIKTVKETSHPNSGISPEELKNAFKNIDLDSPLIDINDVVDELDELYLKHAVYFHHKD
                     YLAHLNCPVLLTSLLAEQISCAINTAVETWDQSAGGTFIEQKVIDWLAYRIGYLKSADG
                     VFTTGGTQSNLMALLLAREQCSTKLDDTKKASLPTNTSKFRILCSEYSHYSIQKAAFVL
                     GLGQEAVISVPANAQRQMDPTALSSTLASLVEQGLIPMAVVATAGTTDFGSIDPIEEIA
                     SLCQQYQCWLHVDAAYGGVLLISNKFPHLLKSIEQADSVSIDFHKSFFQPLCCSALMVS
                     NGQSLSHLTYHADYLNPKHQADNGIPDLANKSLQTSRRFDALKIWLTLRACGPEAIGKL
                     FDDLILNTQEVYQRSQHLTDIKFVQEPQLTTLVFRFVDQRLTPTEQDTCNRAIREALSK
                     SRRALIAATVVKGRQYLKITMLNPQTPVNSIVAVFEAINTCGHSITEQLLTNVKQSA"
     PFAM_domain     2398..3402
                     /aSDomain="Pyridoxal_deC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00282.21"
                     /description="Pyridoxal-dependent decarboxylase conserved
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_142_0001"
                     /evalue="1.60E-66"
                     /label="ctg1_142"
                     /locus_tag="ctg1_142"
                     /protein_end="435"
                     /protein_start="100"
                     /score="224.7"
                     /tool="antismash"
                     /translation="HHKDYLAHLNCPVLLTSLLAEQISCAINTAVETWDQSAGGTFIEQ
                     KVIDWLAYRIGYLKSADGVFTTGGTQSNLMALLLAREQCSTKLDDTKKASLPTNTSKFR
                     ILCSEYSHYSIQKAAFVLGLGQEAVISVPANAQRQMDPTALSSTLASLVEQGLIPMAVV
                     ATAGTTDFGSIDPIEEIASLCQQYQCWLHVDAAYGGVLLISNKFPHLLKSIEQADSVSI
                     DFHKSFFQPLCCSALMVSNGQSLSHLTYHADYLNPKHQADNGIPDLANKSLQTSRRFDA
                     LKIWLTLRACGPEAIGKLFDDLILNTQEVYQRSQHLTDIKFVQEPQLTTLVFRF"
     CDS             3662..4990
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 418.7;
                     E-value: 3.7e-127)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_143"
                     /transl_table=11
                     /translation="VNKNIYDILGVGIGPFNLSLAALSSSVPDCKSIFLDARSHFDWHP
                     GMMLEGTRLQTPFMSDLVTMADPTNEYSFLNYAKLNDRLYPFYIRENFFLAREEYNHYC
                     QWACNRLSNLTFNSCVTHIDYDENEAIYCVKTQNTLLDREETYYCHHLVLGTGTQPYLP
                     DFCSKKEPKVTHSAHYLMNKAELKASTCITVVGSGQSAAEIFYDLLTDIDVEKYRLRWL
                     TRSPRFFSLEYTKLTLEMTSPEYIDYFHQLEPEQRRVLIQKQKHLYKGINADLINDIYD
                     LLYIKQLSHDFTVEMMTNVSVHSLSSEQSQVTLHCLHTETQHNFELQTQHIVMATGYEY
                     QLPQFLDGICAHLRFDSHGELDVQRNYSVDRNNKIFVQNVGLHTHGLTSPDLGMVCYRN
                     ATILNQVLGRTHYKVEKSIAFQQFSPPNCESHLYNATTEHSLE"
     PFAM_domain     3674..4678
                     /aSDomain="K_oxygenase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13434.8"
                     /description="L-lysine 6-monooxygenase (NADPH-requiring)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_143_0002"
                     /evalue="1.90E-118"
                     /label="ctg1_143"
                     /locus_tag="ctg1_143"
                     /protein_end="339"
                     /protein_start="4"
                     /score="395.6"
                     /tool="antismash"
                     /translation="IYDILGVGIGPFNLSLAALSSSVPDCKSIFLDARSHFDWHPGMML
                     EGTRLQTPFMSDLVTMADPTNEYSFLNYAKLNDRLYPFYIRENFFLAREEYNHYCQWAC
                     NRLSNLTFNSCVTHIDYDENEAIYCVKTQNTLLDREETYYCHHLVLGTGTQPYLPDFCS
                     KKEPKVTHSAHYLMNKAELKASTCITVVGSGQSAAEIFYDLLTDIDVEKYRLRWLTRSP
                     RFFSLEYTKLTLEMTSPEYIDYFHQLEPEQRRVLIQKQKHLYKGINADLINDIYDLLYI
                     KQLSHDFTVEMMTNVSVHSLSSEQSQVTLHCLHTETQHNFELQTQHIVMATGYE"
     CDS             5001..7460
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     80.1; E-value: 3.8e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_144"
                     /sec_met_domain="IucA_IucC (E-value: 4.2e-72, bitscore:
                     240.2, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDFTAKAQCSFTDRYAPKKDQLINISEFEFRNYNEDTDFSVINQ
                     WLSQSYSSYWGMNELTEDQRNLELKNTAHKFGLVGLKRGKILFYTELYHPAKDEIGEHY
                     PVQEGDCGMHLIIAPVDIPEHRLSQNVITAISSLILEHLPFTRLVVEPDIQNEKVHRLN
                     HLIGIEYSQIVPLNSKTAKLGFATKSQFLQSQGKVSSMKNSSKNPSLSLATSHLTTEYW
                     HKANQHLIAKMITELSHEQIITPIKLDDASNAQAASWCITFNSDTGTSEYLFRARQYQL
                     DHLFVEPQSITCTKDDKNQPLDAVSFILSCRHLLEISDALLPTYLEEITSTLYSKAYKL
                     MHQNKTSAQLANASYQEIEAAMTEGHPVFIANNGRIGFDMLDHVEFSPESGQSLNLQWI
                     AVLREKTSFAVIESLSYDRLIFDELGQSQLNEFNQQLSMQGLEPSHYYLMPIHPWQWRE
                     KISRIFAADIANQYVVPLGTTEDKYQAQQSIRTFFNLSSPEKCYVKTALSILNMGFMRG
                     LSPYYMSRTPAINTFIANLIETDPYFAKKQFFVLKEVAAIGYHHSYYEQATRTDNPYKK
                     MLSSLWRESPYAPDQHGNVLVNKQQKLLTMASLLHVDDQGKSLISALMADSPLSDHNWL
                     KQYMDLYLQPLLHSFFAYDLVFMPHGENLILVLEDNSPIKIIMKDIGEEVAILNGEKTL
                     PNDMNCLAVDLEDPMKLNYILLDIFDCIFRFIAPLLEQQTQVSESDFWEIVADSVKDYQ
                     QEHPQFDAKYQRYDLYCSSFARTCLNRIQLNNNQQMIDLEDREKNLRFAEDIANPLALF
                     AKTHRII"
     PFAM_domain     5109..5516
                     /aSDomain="Acetyltransf_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13523.8"
                     /description="Acetyltransferase (GNAT) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_144_0003"
                     /evalue="7.50E-30"
                     /label="ctg1_144"
                     /locus_tag="ctg1_144"
                     /protein_end="172"
                     /protein_start="36"
                     /score="103.6"
                     /tool="antismash"
                     /translation="DTDFSVINQWLSQSYSSYWGMNELTEDQRNLELKNTAHKFGLVGL
                     KRGKILFYTELYHPAKDEIGEHYPVQEGDCGMHLIIAPVDIPEHRLSQNVITAISSLIL
                     EHLPFTRLVVEPDIQNEKVHRLNHLIGIEYSQ"
     PFAM_domain     6060..6833
                     /aSDomain="IucA_IucC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04183.14"
                     /description="IucA / IucC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_144_0004"
                     /evalue="4.50E-71"
                     /label="ctg1_144"
                     /locus_tag="ctg1_144"
                     /protein_end="611"
                     /protein_start="353"
                     /score="239.3"
                     /tool="antismash"
                     /translation="SYQEIEAAMTEGHPVFIANNGRIGFDMLDHVEFSPESGQSLNLQW
                     IAVLREKTSFAVIESLSYDRLIFDELGQSQLNEFNQQLSMQGLEPSHYYLMPIHPWQWR
                     EKISRIFAADIANQYVVPLGTTEDKYQAQQSIRTFFNLSSPEKCYVKTALSILNMGFMR
                     GLSPYYMSRTPAINTFIANLIETDPYFAKKQFFVLKEVAAIGYHHSYYEQATRTDNPYK
                     KMLSSLWRESPYAPDQHGNVLVNKQQKLLTMASLLH"
     PFAM_domain     6897..7370
                     /aSDomain="FhuF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06276.14"
                     /description="Ferric iron reductase FhuF-like transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_144_0005"
                     /evalue="2.20E-36"
                     /label="ctg1_144"
                     /locus_tag="ctg1_144"
                     /protein_end="790"
                     /protein_start="632"
                     /score="125.8"
                     /tool="antismash"
                     /translation="NWLKQYMDLYLQPLLHSFFAYDLVFMPHGENLILVLEDNSPIKII
                     MKDIGEEVAILNGEKTLPNDMNCLAVDLEDPMKLNYILLDIFDCIFRFIAPLLEQQTQV
                     SESDFWEIVADSVKDYQQEHPQFDAKYQRYDLYCSSFARTCLNRIQLNNNQQMI"
     CDS             7484..9649
                     /gene_functions="transport (smcogs)
                     SMCOG1051:TonB-dependent siderophore receptor (Score:
                     530.6; E-value: 1.1e-160)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_145"
                     /transl_table=11
                     /translation="MTLNTNMTSPKIPTYSLFYGLSCVLTLPVMAEDNDNEAMEVMTIT
                     AHKQEIASYKTGETSTSTGMDLSYLETPQSVTAVNEQAMKDQQLNSVVDVMNSVSSVYA
                     RPMDNDRYTVSARGMEVSTILYDGVPITYDTRFNYGDNLMDTAIYDRVEVVRGANGLMI
                     GAGEPSASINLIRKRPTHDFNANVSVGTGSWNLKRGVVDISGSVNTDESIRARLVAVHQ
                     ERDSYLDRYEQKRSTLYGVIEADLTTDTLLTVGTDYQYNEPKGTMAGGLPLFHSDGTRT
                     NYSTSATTAPDWASAETTALNSFVSLEHSFNPDWVIKGTYTYGDNSLDFNYLWPKGFPD
                     PNTNEGMVPGSINYIDGNRKINNLNLTLKGHFSLFGQDHQMIAGFNNQKMTFENTYYKG
                     LNAQSEVGDFTDPNWSYPEPEWSREKSWESTGETKQQGIYVASHINVTDQWSFVLGGRL
                     SDWETDMNDFGTLHKNKISNEFTSYVGTTYAITPIVAVYASYSDIFTPQNVKGKNNTYL
                     DPIKGKNYETGIKASLLDDQLNLSLNGFNTLQDNLGIKTGDVDPNTGMPIYRGVDGTET
                     KGFEFETNGAITDDWNLTLGYTYFKIEDPQGNRLKTDIPNKQLKLFTTYELGDVLEGLQ
                     IGGGARWYSSIYKEVSGIPNVGDTKVKQDSYAIYDVMVRYEVNKKLNVNANVKNLFDKE
                     YYSQMGIYNQYHAGEPRNISVNVDYQF"
     PFAM_domain     7694..7987
                     /aSDomain="Plug"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07715.17"
                     /description="TonB-dependent Receptor Plug Domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_145_0006"
                     /evalue="1.80E-13"
                     /label="ctg1_145"
                     /locus_tag="ctg1_145"
                     /protein_end="168"
                     /protein_start="70"
                     /score="51.1"
                     /tool="antismash"
                     /translation="ETPQSVTAVNEQAMKDQQLNSVVDVMNSVSSVYARPMDNDRYTVS
                     ARGMEVSTILYDGVPITYDTRFNYGDNLMDTAIYDRVEVVRGANGLMIGAGEP"
     aSDomain        7694..9646
                     /aSDomain="TIGR01783"
                     /aSTool="tigrfam"
                     /description="TonB-siderophor: TonB-dependent siderophore
                     receptor"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_145_0001"
                     /evalue="1.90E-95"
                     /identifier="TIGR01783"
                     /label="ctg1_145"
                     /locus_tag="ctg1_145"
                     /protein_end="721"
                     /protein_start="70"
                     /score="318.8"
                     /tool="antismash"
                     /translation="ETPQSVTAVNEQAMKDQQLNSVVDVMNSVSSVYARPMDNDRYTVS
                     ARGMEVSTILYDGVPITYDTRFNYGDNLMDTAIYDRVEVVRGANGLMIGAGEPSASINL
                     IRKRPTHDFNANVSVGTGSWNLKRGVVDISGSVNTDESIRARLVAVHQERDSYLDRYEQ
                     KRSTLYGVIEADLTTDTLLTVGTDYQYNEPKGTMAGGLPLFHSDGTRTNYSTSATTAPD
                     WASAETTALNSFVSLEHSFNPDWVIKGTYTYGDNSLDFNYLWPKGFPDPNTNEGMVPGS
                     INYIDGNRKINNLNLTLKGHFSLFGQDHQMIAGFNNQKMTFENTYYKGLNAQSEVGDFT
                     DPNWSYPEPEWSREKSWESTGETKQQGIYVASHINVTDQWSFVLGGRLSDWETDMNDFG
                     TLHKNKISNEFTSYVGTTYAITPIVAVYASYSDIFTPQNVKGKNNTYLDPIKGKNYETG
                     IKASLLDDQLNLSLNGFNTLQDNLGIKTGDVDPNTGMPIYRGVDGTETKGFEFETNGAI
                     TDDWNLTLGYTYFKIEDPQGNRLKTDIPNKQLKLFTTYELGDVLEGLQIGGGARWYSSI
                     YKEVSGIPNVGDTKVKQDSYAIYDVMVRYEVNKKLNVNANVKNLFDKEYYSQMGIYNQY
                     HAGEPRNISVNVDYQF"
     PFAM_domain     8219..9640
                     /aSDomain="TonB_dep_Rec"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00593.26"
                     /description="TonB dependent receptor"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_145_0007"
                     /evalue="3.90E-47"
                     /label="ctg1_145"
                     /locus_tag="ctg1_145"
                     /protein_end="719"
                     /protein_start="245"
                     /score="162.3"
                     /tool="antismash"
                     /translation="LTTDTLLTVGTDYQYNEPKGTMAGGLPLFHSDGTRTNYSTSATTA
                     PDWASAETTALNSFVSLEHSFNPDWVIKGTYTYGDNSLDFNYLWPKGFPDPNTNEGMVP
                     GSINYIDGNRKINNLNLTLKGHFSLFGQDHQMIAGFNNQKMTFENTYYKGLNAQSEVGD
                     FTDPNWSYPEPEWSREKSWESTGETKQQGIYVASHINVTDQWSFVLGGRLSDWETDMND
                     FGTLHKNKISNEFTSYVGTTYAITPIVAVYASYSDIFTPQNVKGKNNTYLDPIKGKNYE
                     TGIKASLLDDQLNLSLNGFNTLQDNLGIKTGDVDPNTGMPIYRGVDGTETKGFEFETNG
                     AITDDWNLTLGYTYFKIEDPQGNRLKTDIPNKQLKLFTTYELGDVLEGLQIGGGARWYS
                     SIYKEVSGIPNVGDTKVKQDSYAIYDVMVRYEVNKKLNVNANVKNLFDKEYYSQMGIYN
                     QYHAGEPRNISVNVDY"
     CDS             9768..10718
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 163.3; E-value:
                     1e-49)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_146"
                     /transl_table=11
                     /translation="MSSHTAAIPLNQISSSPFPVTIKTAHGTAVIPTHPQRVITLGATT
                     EDWCLLLGIVPIAIEAHYWGGDSKGYLPWFKQAVLEQEKALPSVLNSYPELDIEHILSL
                     KPDLILAPQSGITLETFNQLNSFVPVVAYPDQPWLTPIDKQVTLISTALGKTEEGEALL
                     VQLHQYLASLADANPQFKGKKLAYINAGSRFGNLALYVPGDPRIDSLLALGFIQLPEVK
                     DIKPTRGHFTANIGLEHSDIFNDADLIISWYESEKSKQAVEKIPLFSHINAVKQGRYLA
                     ITDPSIVMATSYGSLLSLEWVMPAFIPKIKEVMGK"
     PFAM_domain     10005..10607
                     /aSDomain="Peripla_BP_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01497.20"
                     /description="Periplasmic binding protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_146_0008"
                     /evalue="1.20E-18"
                     /label="ctg1_146"
                     /locus_tag="ctg1_146"
                     /protein_end="280"
                     /protein_start="79"
                     /score="67.6"
                     /tool="antismash"
                     /translation="LEQEKALPSVLNSYPELDIEHILSLKPDLILAPQSGITLETFNQL
                     NSFVPVVAYPDQPWLTPIDKQVTLISTALGKTEEGEALLVQLHQYLASLADANPQFKGK
                     KLAYINAGSRFGNLALYVPGDPRIDSLLALGFIQLPEVKDIKPTRGHFTANIGLEHSDI
                     FNDADLIISWYESEKSKQAVEKIPLFSHINAVKQGRYL"
     CDS             10715..11815
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 265.1; E-value: 1.2e-80)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_147"
                     /transl_table=11
                     /translation="MNNADNQLTSTPDLAILPSLISRNKKVTTTLILLIILSFSAIISG
                     LLLGTTTLSPFYLLRLFSENNLNHDTLIIQARLPRVLIGLLAGMSLAMAGCVMQALTRN
                     PLADPGLLGVNAGANASIITLSLLSFSANWPLFWLAIPGALLTSVMVYLLSRGHNQSPT
                     RLILSGAAISAVLGAYVQARVIVNPSLFSDLKYWMSGSLSGLQLSDINTIWPYFIIATV
                     ILLLLAPALNLLSIDRNIAISLGANLRWQPQLGWLGATILCAASTATVGSLTFVGLASA
                     HLSRFIAPQDFRWQLPISALIGGNLVVIADVIARTLMPPTELITGIVVAMLGAPFLYLA
                     VRRDQMKKSSSVTPCKRRLKRNSNEN"
     PFAM_domain     10835..11743
                     /aSDomain="FecCD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01032.20"
                     /description="FecCD transport family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_147_0009"
                     /evalue="1.50E-76"
                     /label="ctg1_147"
                     /locus_tag="ctg1_147"
                     /protein_end="343"
                     /protein_start="40"
                     /score="257.5"
                     /tool="antismash"
                     /translation="AIISGLLLGTTTLSPFYLLRLFSENNLNHDTLIIQARLPRVLIGL
                     LAGMSLAMAGCVMQALTRNPLADPGLLGVNAGANASIITLSLLSFSANWPLFWLAIPGA
                     LLTSVMVYLLSRGHNQSPTRLILSGAAISAVLGAYVQARVIVNPSLFSDLKYWMSGSLS
                     GLQLSDINTIWPYFIIATVILLLLAPALNLLSIDRNIAISLGANLRWQPQLGWLGATIL
                     CAASTATVGSLTFVGLASAHLSRFIAPQDFRWQLPISALIGGNLVVIADVIARTLMPPT
                     ELITGIVVAMLGAPFLYLAVRR"
ORIGIN
        1 tttacaagat ggcgcagtaa gtacctctct gaatgcagag gcacaatact gtgaataaac
       61 taaccgtatc gctcatgata ggcgccttac ttccattaaa tgtaaatgcc aactcatgca
      121 aaatcgaagg ttacaccatc ggctttttta atggggttgc gacgacgaag aaagatgctg
      181 aacgtgggcg agataaaatc aaatctactc ttgatatcac tcaatacaac ggtgaaaaag
      241 tggagtacca acttttctat aacgattctt acattgaaag taatggcttt aacgtactgg
      301 ctgatttcgc cgaaaccttt gaccaaagaa ctcaagagct agagcaaaaa caatttgacc
      361 gatgggaagc gttttgggat atcgttaacg gcaagcaaga tagctctatc atcaaaaaaa
      421 tcagtgctgc attttcttgg tttggggggt tttttactga cttcaacagt caacgttcca
      481 atatcatcat ccgcgaattt ctagaattat taaccctatc ggttgattct ccagatacag
      541 caaagactca gatgcagcat aagctcatca atgattccaa tacatggcaa gggaaaaagc
      601 tgatttatat tgcccattct caaggaaact tatgggtaaa taaatcgtac aactatgttg
      661 tgtctcaatt aggttatgat gcaagtaata ttcatgtcgt tcatatcgcg ccagcctctc
      721 caacattaag tcctaatagc gattacattt tatctagctc agaccttgtc attaacggat
      781 taaattttac aggggtgggc tcagtgcctc catttaacac aataattgca cctagttctt
      841 ctgacattgc aggacatggt ttaattgagg tttatttaac tcaccctaaa tcgatacaaa
      901 aaataaaatc cgctacggat aaagcattcg catcactcac caaaccagac atggaggatg
      961 tactgttttc aattgattat aattacaccc ccactttttc tgaaagccat gcttcaccag
     1021 aaattgaatt tgttgataat aataacaatt gggtaaagag aacggacatt tattcagaga
     1081 tctcttactt acaaagagca gatccaaacg aaaataaata tgagctgaat cccgccaaag
     1141 attttgaacc actttcattc atacataata agaaggacag agagagtcaa gtaataagca
     1201 tagatcaatg ctctgacata ccaaacaatg accccttcat attgggagag caatctaacg
     1261 aaaccataag atacgcatgg gataaggtgc caccaaatac gaaggtatcg gttacggtca
     1321 gagatagata tggtgtgaag ttacaaaatg acgaagtatc tatcaatgaa cttcgtccta
     1381 gaggacatac ttatcagggg atttttattg atctaaacgc aattaaccct tacacaaaag
     1441 aagaaaaagc atttataaaa caacaaaagc tagagactaa atacgaactt tattcagact
     1501 caattctatt ttctatctca tcttaatctc tcctcatttt gtatggtcaa ctttagttaa
     1561 gtgggccgtt attacgtaac aataattaac tttcctattt attcactttt cttcttattt
     1621 aattacattc attgttattt ttaaaattac gttataccta gatcataatc acatgttttt
     1681 atattaaact tattgatata aaggacagta tattgatcgt cactaaaaaa taaaattaat
     1741 agtccatttg tttccgttta atttgaaaat aaaagtaatt catcctcttt taacggaggg
     1801 ttagtaatta ttatcgtaaa tttaaaaagg tattaactct taaattcacc tcattttttt
     1861 aatacaaaaa aatattttca gattaaattt cactcatcaa ttcccgctca agccttactc
     1921 taactaggta gaagttaaaa ttaacaaaaa ccacaaaaca accatgggaa tgataatcat
     1981 tttcatttga gttttatcat gatagattcc atacactctc aaaaacaaag ataaataata
     2041 catctcagtt aattacatgg gatttcattc aacattgata aatgcacaga gaaaaatatg
     2101 gatactaaat attttgaaaa aaacgccaat aacgatactc tctttaacca aagtagtctc
     2161 ttaagtaatg tggatttttt tgattcaagt tctttagatc attataaaga aatcacagag
     2221 ttagggctca acacgcttat taaaacagta aaagaaacat cacaccctaa ttctgggatc
     2281 tcgccagaag aattaaagaa cgccttcaaa aatatagatt tagattctcc tttaattgat
     2341 attaatgatg ttgtagatga attggatgag ctttacctta agcatgctgt ctatttccat
     2401 cataaagatt acttagcgca tttaaattgc cctgtattat taacctcatt attagctgag
     2461 caaattagct gtgcgattaa taccgcggtt gaaacctggg atcaaagtgc cggtggtaca
     2521 ttcattgaac agaaagtaat agattggctt gcataccgta taggttatct aaagtctgcc
     2581 gatggtgtat ttaccactgg aggtacacaa tctaatctaa tggcactgtt actggccaga
     2641 gagcaatgca gcactaaact tgatgacacc aagaaagcat cattacctac caataccagt
     2701 aaattccgta ttctttgttc tgaatacagc cattatagta ttcaaaaagc ggcattcgtt
     2761 ttaggcttag gtcaagaggc ggtaattagt gttcctgcta acgctcagcg acaaatggat
     2821 ccgactgcgc tttcatcaac attggcatca ctggtagagc aaggattaat tccaatggcg
     2881 gtggttgcta ccgctggcac caccgatttt ggttctatcg atcctatcga agagatagct
     2941 tctctttgtc agcaatatca atgttggttg catgtagacg cggcatacgg tggcgtatta
     3001 ctgatttcga ataaatttcc tcacttattg aaaagtattg aacaagccga ttctgttagc
     3061 atcgattttc ataaatcatt tttccaacct ttatgctgct cagcccttat ggtgagtaat
     3121 ggtcaatctc tttctcatct tacctatcat gccgattacc taaacccaaa acaccaagcc
     3181 gataatggta ttcctgacct tgccaacaaa agtcttcaaa catcacgacg attcgacgct
     3241 ttaaagattt ggcttacttt acgagcttgc gggccagaag ccatcggtaa gttatttgat
     3301 gacttaatcc ttaatactca agaagtctat caacgcagtc agcacctaac cgatattaag
     3361 tttgttcaag agccacaact gaccacattg gtatttagat tcgtcgacca acgccttacc
     3421 ccgacagaac aggacacctg caacagggca attagagagg cactttctaa atcaagaaga
     3481 gcgttaatcg cagcaaccgt ggttaaaggt cgtcaatatc tcaaaataac gatgttaaac
     3541 cctcaaaccc ccgtgaacag catcgttgcc gtatttgaag ccattaatac gtgtggtcat
     3601 tcaatcaccg agcaactgct taccaatgta aaacaaagcg cctaataaaa aaggatatcc
     3661 agtgaataaa aatatatacg atattttagg tgtcggtatt ggtccattta atcttagcct
     3721 tgccgccctt tcttcctctg ttcctgactg taaaagcatt tttcttgatg ctcgtagcca
     3781 cttcgattgg cacccaggga tgatgttaga gggcacaaga ttacagacac cttttatgtc
     3841 tgaccttgtc acaatggctg atccaaccaa tgaatacagt tttcttaact acgcaaaatt
     3901 aaatgatcgt ctgtaccctt tttatataag agaaaacttc tttttagcca gagaagaata
     3961 caaccactat tgccaatggg cttgtaaccg cctatcaaac ctaacgttta atagctgcgt
     4021 cacccatatt gattatgatg aaaatgaggc gatatattgc gtaaaaacac aaaacacgtt
     4081 actggatcgt gaagaaacct attactgcca tcatttagtt ctcggcactg ggacacagcc
     4141 ttacctgcct gacttttgca gtaaaaagga accgaaagtg acccactctg ctcactacct
     4201 aatgaataaa gcagaattaa aagcgtctac ctgcatcact gttgttggta gtggtcaaag
     4261 tgcggctgag attttctatg atttattaac cgacatcgac gtagaaaagt accgtcttcg
     4321 ctggctaacg cgttctcctc gattcttctc attggagtat acaaaactca cattggaaat
     4381 gacgtcacca gaatacatcg actatttcca tcaacttgaa ccagagcaac gccgagtatt
     4441 aatccagaaa caaaagcacc tatataaagg cattaacgcc gatttgatta atgatattta
     4501 tgatctttta tacattaaac agttatcaca tgactttact gttgaaatga tgacgaacgt
     4561 ttctgttcac tctttatcaa gcgaacaatc acaggtaacg cttcattgtc tgcacactga
     4621 aactcaacat aatttcgaac tacagactca acacattgtg atggcaacgg gttatgaata
     4681 tcaattacct caatttctag atggcatttg cgcgcattta cgctttgatt cacatggaga
     4741 acttgatgtt cagcgaaact acagcgttga tagaaacaac aaaatcttcg tacaaaacgt
     4801 tggcttacat actcatgggc tgacttcccc agatcttgga atggtgtgct atagaaacgc
     4861 gaccattttg aatcaggtac ttggcagaac ccactacaaa gtagaaaaat ccatcgcctt
     4921 tcagcaattc tctcctccaa attgcgaaag tcatttatat aacgcaacca ctgaacactc
     4981 actcgaataa agagataacg atgacagatt tcacagccaa agctcaatgt agctttacgg
     5041 atcgttacgc gccaaaaaaa gaccaattaa tcaatatctc tgaatttgag ttcagaaatt
     5101 acaacgaaga caccgatttt agcgttatta atcaatggtt atctcagagt tattcatcgt
     5161 attggggaat gaatgaactt accgaagatc agcgcaacct tgagctaaaa aacacagccc
     5221 ataaatttgg actggtggga ctaaaacgcg gaaaaatact gttttatacc gagctatatc
     5281 atccagcgaa agacgaaata ggtgagcatt acccagttca agaaggtgac tgtggcatgc
     5341 acttgattat cgctcccgtt gatattccag agcatcgttt aagtcaaaac gtcattaccg
     5401 caatctcgtc attaatttta gaacacctgc cttttacaag gctcgttgtt gaaccggata
     5461 tccaaaatga gaaagtacac cgtttaaacc acttaatagg tattgagtac agtcaaatcg
     5521 ttccgcttaa cagcaaaacc gcaaaattag ggtttgctac taagtcacaa tttttgcagt
     5581 cacaagggaa agtatcttca atgaaaaata gcagtaagaa tccatcatta tcactcgcca
     5641 cttctcattt aacgacagag tattggcata aagcgaatca acatttaatc gcgaaaatga
     5701 tcaccgagtt gagccatgag caaatcatca caccgataaa attagatgat gcatcaaatg
     5761 cacaagccgc ctcttggtgt atcaccttca actcggatac gggaacgtct gaatacctct
     5821 ttcgtgcacg ccaatatcaa ctcgatcatt tatttgttga accacaatca atcacttgca
     5881 ctaaagatga taaaaaccaa cctcttgatg ccgtctcttt tattctttct tgtcgtcacc
     5941 ttcttgagat cagtgatgca ttgttaccta cgtatttaga ggaaatcact agcacgctat
     6001 acagcaaagc ctataagctc atgcaccaaa ataagacctc agctcaatta gcgaatgcaa
     6061 gctaccaaga gattgaagct gccatgacag aaggtcatcc agtattcatt gctaataacg
     6121 gcagaattgg ctttgatatg ttagatcatg ttgaattttc accagaaagt ggacaatcat
     6181 taaatttaca atggattgca gtgctgcgtg aaaaaacaag ctttgccgtc atcgaatcat
     6241 taagctacga ccgcctaatt tttgatgaat taggtcaatc acaactgaat gagttcaatc
     6301 aacaactctc tatgcaaggg cttgaaccat cacattatta cttaatgccc atccacccat
     6361 ggcaatggcg agaaaaaata tcacgtatct tcgccgctga tatcgccaat cagtatgtag
     6421 ttcctcttgg cacgacggaa gataagtatc aagcacagca atctattcga acctttttta
     6481 acctttcttc accagaaaag tgctatgtga aaaccgcctt atcgatttta aatatgggct
     6541 tcatgcgtgg gttatctccg tattacatga gccgaacacc ggctatcaat acgttcattg
     6601 caaacctcat tgaaaccgat ccctactttg ctaaaaagca attttttgtt cttaaagaag
     6661 tcgcggcaat aggctatcac cacagctact atgagcaagc tactcgcact gacaatcctt
     6721 ataaaaaaat gctttcttct ttatggcgtg aaagtccata cgcaccagat caacatggca
     6781 atgtattggt aaacaagcag caaaaactac tgacaatggc ttcattactg catgttgatg
     6841 accaaggaaa aagcctgata tcagcgttaa tggccgattc gccgttgtct gatcataact
     6901 ggcttaagca gtacatggat ctttatctac aacctcttct gcacagcttt tttgcttatg
     6961 atcttgtctt tatgccacac ggtgaaaact taattttagt acttgaagac aacagcccaa
     7021 tcaaaataat catgaaagac atcggggaag aagtggccat tttaaatgga gaaaaaactc
     7081 taccaaatga catgaattgc ttggcagttg atcttgaaga cccaatgaaa cttaactaca
     7141 ttttgctcga tatttttgat tgtattttcc gattcatcgc tccattgctt gagcaacaaa
     7201 ctcaggttag cgaatctgat ttttgggaga tagttgccga ttcagtcaaa gactaccaac
     7261 aagaacaccc gcaatttgat gcgaaatatc aacgttacga tctgtattgc agctcgttcg
     7321 cccgtacctg cctaaatcga attcaactaa acaataatca gcaaatgatt gaccttgaag
     7381 atagagaaaa gaacttacgt tttgctgagg atattgcaaa ccctctcgct ctatttgcta
     7441 agactcatcg cattatttag ttcactgact tttaggccaa acaatgacat tgaatacgaa
     7501 catgacatca ccaaaaatac cgacatactc acttttctat gggttatctt gtgttttaac
     7561 gttgccagta atggcagagg acaatgataa cgaggcaatg gaagtaatga ccattaccgc
     7621 gcataaacaa gagattgcca gctataaaac aggtgaaacc tcaacctcaa cagggatgga
     7681 tttatcctat ttagaaacac cacaatctgt aactgccgtg aacgaacaag ccatgaaaga
     7741 tcaacaacta aacagtgttg ttgatgtaat gaacagcgta tcgagtgttt acgctcgacc
     7801 tatggacaac gacagataca ccgtctctgc tcgtggtatg gaagtaagca ccattcttta
     7861 tgatggcgtt cctatcacct atgacacccg tttcaattac ggtgataacc taatggatac
     7921 ggcgatttat gatcgcgttg aagtggttcg cggtgcgaac ggattaatga ttggtgcagg
     7981 cgagccttca gcctctatca accttattag aaaacgtcct actcacgatt ttaatgccaa
     8041 tgttagcgta ggcacgggat cttggaattt aaaacgtggg gtcgttgata tctctggcag
     8101 cgtaaatact gatgaaagta ttagagctcg tcttgttgct gtccatcaag aacgtgactc
     8161 ctacttagac agatacgaac agaaaagaag tacattatat ggcgttattg aggccgattt
     8221 aaccaccgac accttattaa cggtcggtac cgattatcaa tataacgagc caaaaggcac
     8281 catggcggga ggacttcccc tctttcatag cgatggtacg agaacaaatt acagcacatc
     8341 agcaaccacc gctcctgact gggcatccgc tgaaaccaca gcattaaatt catttgtcag
     8401 tctagagcat agctttaacc cagattgggt aataaaagga acgtatacct atggtgataa
     8461 cagcttagat ttcaattatt tatggccgaa aggttttcct gacccaaata caaatgaagg
     8521 tatggttcca ggcagtatta attatattga tggaaatcga aaaattaata atcttaacct
     8581 aactctcaaa ggtcattttt ctctgtttgg acaagatcac caaatgatcg cgggtttcaa
     8641 caatcaaaaa atgacgttcg agaatactta ctataaaggg ctaaacgcac aatcagaggt
     8701 cggtgatttt actgacccaa attggtctta tccagaaccg gaatggagca gagaaaaaag
     8761 ctgggaatca acaggagaaa ccaaacaaca agggatctat gtcgcctcac atatcaatgt
     8821 aactgaccag tggtctttcg ttcttggtgg acgattgagt gactgggaaa ccgatatgaa
     8881 tgactttgga acccttcata aaaataaaat cagtaatgaa tttacctcat acgttgggac
     8941 gacttatgca ataaccccca ttgttgcggt atacgccagt tactctgata ttttcacacc
     9001 gcaaaacgta aaaggtaaaa ataatacgta tctcgacccg attaaaggaa agaactatga
     9061 aacaggaatt aaagcaagcc tcttggatga tcagttaaac ctttctctta atggcttcaa
     9121 cacgttacag gataatttag gaataaaaac tggcgacgtc gatccaaata cagggatgcc
     9181 tatttatcgt ggtgttgatg gtacagaaac caaagggttc gagtttgaaa ccaatggtgc
     9241 catcacagat gactggaact taacgcttgg ctatacctat ttcaaaatag aagatccaca
     9301 aggaaataga ttaaaaacag acatccctaa caaacaactc aaactcttca ccacttatga
     9361 attaggtgac gttttagagg gcctccaaat tggcggaggg gctcgttggt acagcagtat
     9421 ttataaagaa gtaagcggta tacctaatgt tggagatacc aaagtaaaac aagacagtta
     9481 cgcgatatac gatgtaatgg tgcgatatga ggtaaacaaa aaacttaacg tcaatgcaaa
     9541 tgttaaaaac ctttttgata aagaatatta cagccagatg gggatctata accaatatca
     9601 cgctggcgag cctcgtaata taagcgtgaa tgttgactac caattttaag accaacgctg
     9661 ttcattcatt tatctcaaat ttacttggag gcccctaccg taaggtaggg cgacatttta
     9721 taactatatt aaaatggcca aaagcaatct ctctgctgtt tatattcatg agtagccaca
     9781 ctgctgctat tcccttaaac caaataagca gctccccatt ccctgtcacc attaaaaccg
     9841 cgcatggaac cgcggttatt cctactcacc cgcaacgcgt catcactcta ggcgcaacaa
     9901 ccgaagattg gtgcttgctc ttaggcattg tgcctatcgc cattgaagct cattattggg
     9961 gtggtgacag caaaggttat ctaccttggt ttaaacaagc cgtcctagaa caagaaaaag
    10021 ccttaccctc agtactcaat agctaccctg aactcgatat cgagcatatt ttatcattaa
    10081 aacccgacct aattttagcg ccacaatctg ggatcacact cgaaacgttt aaccaattaa
    10141 acagttttgt tcctgttgtt gcttatccag atcaaccttg gcttacccct atcgataagc
    10201 aagttaccct catttcaacg gctttaggaa aaacagaaga aggagaggcc ctgcttgttc
    10261 aattacacca ataccttgct tcacttgccg atgcaaaccc tcaatttaaa ggtaaaaaac
    10321 tggcgtatat taatgcagga agtcgattcg gtaatcttgc gttgtatgta cctggcgatc
    10381 cacgtatcga ttctctactc gcactcggct ttatacaact tcctgaagtc aaagacataa
    10441 aaccaactcg tggacatttc acggccaaca ttggtttaga gcactccgat atatttaatg
    10501 atgccgatct cattattagt tggtatgagt ctgaaaaaag caaacaagcc gttgaaaaaa
    10561 tcccgctttt ctcacacatc aacgccgtta agcaaggacg atatcttgcg ataaccgatc
    10621 cctcaattgt aatggcgacg tcctatggca gtttactcag tttggaatgg gtaatgcccg
    10681 catttattcc aaaaatcaaa gaggttatgg gtaaatgaat aacgcagata accaattaac
    10741 tagtacacct gacttggcta ttctcccttc tttaatcagc agaaataaaa aggtcactac
    10801 cacattaata ttgctaatta tattaagttt ttctgcaatt atttctgggc ttcttttagg
    10861 aacaacaacc ctatctccct tttatctact gcgcttattt agtgaaaata atctcaatca
    10921 cgatactctt attatacaag ctcgactccc acgagttctg attggtttat tggctggaat
    10981 gtcattagca atggcaggct gcgtcatgca agccttaact cgaaaccctt tagctgatcc
    11041 gggtttactc ggtgtaaatg cgggagcgaa tgcctcaata ataacactca gcttattatc
    11101 attcagtgcc aactggcctc ttttttggtt agcgattcct ggtgcgttac tcacgagcgt
    11161 gatggtctac ttattgtcac gaggccacaa tcaatcccca acaaggctta tcctatctgg
    11221 tgccgccatt agtgccgtat taggtgctta tgtgcaagca agagtcatcg taaacccatc
    11281 gctttttagt gacctaaagt attggatgtc ggggtcatta tcaggactcc aactatctga
    11341 tattaatacg atatggcctt actttattat cgctactgtc attcttcttc tattagctcc
    11401 tgctttaaat ttactctcta tcgatagaaa cattgcgata tccttggggg cgaatttacg
    11461 atggcagccg caactaggtt ggcttggcgc tacgattttg tgtgcggcct caaccgccac
    11521 cgtcgggtca ctgacttttg ttggtttagc atccgcccac ctttctcgat ttattgcccc
    11581 acaggatttt cgctggcaat tgcccatatc ggcactcatt ggcggtaacc ttgttgttat
    11641 tgctgatgtg atcgcccgaa cactcatgcc tccgacagag cttattactg gcatcgttgt
    11701 cgctatgctc ggcgctcctt ttctctacct cgcagtgaga agagatcaaa tgaaaaagtc
    11761 gtcatcagta acaccttgta aacgacgtct gaagagaaac tcaaatgaaa actaatttag
    11821 tctcaacatg gcagttaggg tcaatcgtaa tactggcccc aagcaaaagg acactcaacg
    11881 ccgtaatcat ggcgatgata ttaatcaccc tatctctggt ttttagttta atgttaggca
    11941 agaatggcat aacacctgat gattttataa cgctatttaa aggtgaagcg tccccatacc
    12001 aagattggtt gttttggcaa tccagattac caagggtttt gtgtgccatc ggagccggtg
    12061 ccgcactcgg tatttctggg gcagtatttc aaacgttaac taaaaatcca ttaggcagcc
    12121 ctgacattat tggtataaac gccggagcaa gtgctggcgc agtattgtgg ttatggtttt
    12181 tgccgaatca accaatagct attggtgcct tactcggtgc cgtctctgtt ttaacaatca
    12241 tgctgatcgc attagggaaa tcgtggcaat tatcacgaca actggttctg cttgggatcg
    12301 ccatcaatgc ctttgctgtc gcgaccgttc aactcatttt aactctggtt caacgagaac
    12361 aagctcagca gctttttggt taccttagtg gcagtttagc caaccgaaat tggcaagacg
    12421 tttccgtcat cttcatgact cttattattt ttgttccact
//
