LOCUS       NZ_KB849705.1           9432 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KB849705.1 Acinetobacter johnsonii ANC 3681 acLro-supercont1.4,
            whole genome shotgun sequence.
ACCESSION   NZ_KB849705
VERSION     NZ_KB849705.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:12:19
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 977799
            Orig. end    :: 987231
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1053)
                     /locus_tag="ctg4_918"
                     /transl_table=11
                     /translation="VRQTKINNKNSYLSLLFYELSANVFMRVFKSKVVVNYKILCVFGV
                     LGSVLQGCTSLGNIAQAPFKNIASPQELIVERKINDSDKNSKEYVYHTVGVKNEKDIEA
                     LYPRSMFSQYCQAHGGRFSQTQKSSFSLVKDPWAKKLLRTYNSLKQGTGTFRCQLNNGE
                     QWLVSIEALSERKLPNSNDTRVVNLQSKVLTEPAPRSMTPITPSKKAVTKAPVIKAEVK
                     KEEESKKEVELKKENKVEVPPKAAKAVETPQQQQAKLYVSARRDINSGRNQVAACNSAQ
                     RAYNYGRLPGSDASNVYTESGILVARCLTGIPSYSSRFSNPKGQAKYVLQNLAKNHNHT
                     GAKNMLKQMK"
     protocluster    1..9432
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[982116:983541](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(4318..5742)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..9432
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9432
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1197..2393)
                     /locus_tag="ctg4_919"
                     /transl_table=11
                     /translation="MFKSFFPNPRWFFISLIVWFIVNLSLWYSGGSGWGSWIGFPAGYA
                     EADLVIGVSRFWSPAFLWFYLWFFVSTCLFALFWRFFSDNKWQRWSVWGSAFILFNIWF
                     GVQVSVVVNAWYNPFYDLIQEMLSNGGGDVNTLYTGVLTFLYVAMVAVTLMVLNLFFVS
                     HYVFRWRTAMNEYYTEHWEKLRHIEGASQRIQEDTMRFAKTTESLGVNLVEALMTLIAF
                     LPVLFSLSMHVKALPVVGEIPHALVWAAVGWAVFGTVVLMVVGAKLPGLEFNNQKVEAA
                     YRKELVYGEDHAERADPVSLKELFSKVRLNYFRLYFHYAYFNLVRIWYMQLDNIYGLFV
                     LFPSIAAGAITLGLMMQIANVFGKVRESFQYLIASWPTIIELLSIYKRLKAFEATLDD"
     PFAM_domain     complement(1206..2144)
                     /aSDomain="SbmA_BacA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05992.14"
                     /description="SbmA/BacA-like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_919_0014"
                     /evalue="1.70E-155"
                     /label="ctg4_919"
                     /locus_tag="ctg4_919"
                     /protein_end="396"
                     /protein_start="83"
                     /score="517.3"
                     /tool="antismash"
                     /translation="DNKWQRWSVWGSAFILFNIWFGVQVSVVVNAWYNPFYDLIQEMLS
                     NGGGDVNTLYTGVLTFLYVAMVAVTLMVLNLFFVSHYVFRWRTAMNEYYTEHWEKLRHI
                     EGASQRIQEDTMRFAKTTESLGVNLVEALMTLIAFLPVLFSLSMHVKALPVVGEIPHAL
                     VWAAVGWAVFGTVVLMVVGAKLPGLEFNNQKVEAAYRKELVYGEDHAERADPVSLKELF
                     SKVRLNYFRLYFHYAYFNLVRIWYMQLDNIYGLFVLFPSIAAGAITLGLMMQIANVFGK
                     VRESFQYLIASWPTIIELLSIYKRLKAFEATL"
     CDS             2843..3037
                     /locus_tag="ctg4_920"
                     /transl_table=11
                     /translation="METLVLELIKPLTLTKEDFPPINFEEGTVLKVLMKTPTGYLVTAD
                     SRFNFTVSFDDENQVWQKL"
     CDS             complement(3495..4280)
                     /NRPS_PKS="Domain: PKS_KR (8-163). E-value: 6.9e-10. Score:
                     30.9. Matches aSDomain: nrpspksdomains_ctg4_921_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     225; E-value: 1.7e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_921"
                     /sec_met_domain="adh_short (E-value: 2.9e-33, bitscore:
                     112.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQLLKDKVAFITGSASGIGHEIAKKFASEGAKVVISDMNAEKCA
                     ETVAALQKQGFEALSAPCDVTNEEAYKTAIELTQKTYGRLDILINNAGFQHVAVIEDFP
                     TAVYQKLINVMLVGSFIGIKYVFPIMKAQQFGRVINMASINGLIGFAGKAGYNSAKHGV
                     IGLTKVAALECARDGITVNALCPGYVDTPLVRGQIHDLAKTRNVSEQSALEDVILAMVP
                     QKRLLSVEEIADYAIFLASDKAGGITGQAVVMDGGYTAQ"
     aSDomain        complement(3498..4259)
                     /aSDomain="TIGR01963"
                     /aSTool="tigrfam"
                     /description="PHB_DH: 3-hydroxybutyrate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_921_0002"
                     /evalue="8.60E-106"
                     /identifier="TIGR01963"
                     /label="ctg4_921"
                     /locus_tag="ctg4_921"
                     /protein_end="261"
                     /protein_start="7"
                     /score="350.8"
                     /tool="antismash"
                     /translation="KVAFITGSASGIGHEIAKKFASEGAKVVISDMNAEKCAETVAALQ
                     KQGFEALSAPCDVTNEEAYKTAIELTQKTYGRLDILINNAGFQHVAVIEDFPTAVYQKL
                     INVMLVGSFIGIKYVFPIMKAQQFGRVINMASINGLIGFAGKAGYNSAKHGVIGLTKVA
                     ALECARDGITVNALCPGYVDTPLVRGQIHDLAKTRNVSEQSALEDVILAMVPQKRLLSV
                     EEIADYAIFLASDKAGGITGQAVVMDGGYTAQ"
     PFAM_domain     complement(3504..4241)
                     /aSDomain="adh_short_C2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13561.8"
                     /description="Enoyl-(Acyl carrier protein) reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_921_0015"
                     /evalue="2.50E-64"
                     /label="ctg4_921"
                     /locus_tag="ctg4_921"
                     /protein_end="259"
                     /protein_start="13"
                     /score="217.2"
                     /tool="antismash"
                     /translation="GSASGIGHEIAKKFASEGAKVVISDMNAEKCAETVAALQKQGFEA
                     LSAPCDVTNEEAYKTAIELTQKTYGRLDILINNAGFQHVAVIEDFPTAVYQKLINVMLV
                     GSFIGIKYVFPIMKAQQFGRVINMASINGLIGFAGKAGYNSAKHGVIGLTKVAALECAR
                     DGITVNALCPGYVDTPLVRGQIHDLAKTRNVSEQSALEDVILAMVPQKRLLSVEEIADY
                     AIFLASDKAGGITGQAVVMDGGYT"
     aSDomain        complement(3792..4256)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_921_PKS_KR.1"
                     /evalue="6.90E-10"
                     /label="ctg4_921_PKS_KR.1"
                     /locus_tag="ctg4_921"
                     /protein_end="163"
                     /protein_start="8"
                     /score="30.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAFITGSASGIGHEIAKKFASEGAKVVISDMNAEKCAETVAALQK
                     QGFEALSAPCDVTNEEAYKTAIELTQKTYGRLDILINNAGFQHVAVIEDFPTAVYQKLI
                     NVMLVGSFIGIKYVFPIMKAQQFGRVINMASINGLIGFAGKAGYNSAKHGV"
     CDS_motif       complement(4176..4247)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_921_0001"
                     /evalue="3.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg4_921"
                     /protein_end="35"
                     /protein_start="11"
                     /score="13.1"
                     /tool="antismash"
                     /translation="ITGSASGIGHEIAKKFASEGAKVV"
     CDS             complement(4318..5742)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03651"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_922"
                     /sec_met_domain="TIGR03651 (E-value: 0.00015, bitscore:
                     18.8, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWDLGVILLSLGLLMYTAYRGFSVILMAPICALLAVLLINPANVL
                     PFYSGVFMPKMVGFIKDYFLVFLLGAIFGKVVEMSGIAESIAKTIVNLIGSKNAMLTVV
                     LLGAILTYSGVSLFVVVFAVYPFANQLFRQANIPKRLIPGTIALGAFTFTMDALPGTPQ
                     IQNVIPTTFFGTDIYAAPFLGLIGAVFVLATGLSYLEWRRRVAARNGDGYATGIELTEA
                     EQQQLKQNLDTTSNGTTARQWLAFVPLILVAVTNKYLSTAIKEWYPNGFDFNAIGLAAY
                     TVDVAKTSAIWAVGLALIVGIIAAISFDFRRVYTGFKDGVNASIGGSLLAVMNTASEYG
                     FGAIIAALPGFAIISHALGNTFTNPLVNGAVTTTVLAGVTGSASGGMSIALSAMADQYN
                     AAILAMGIPPEVMHRIVAMASGGMDTLPHNGAVITLLAVTGLTHKQSYKDIFAITIIKT
                     IAVFVAIAAFTWFGIV"
     PFAM_domain     complement(4354..5550)
                     /aSDomain="GntP_permease"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02447.18"
                     /description="GntP family permease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_922_0016"
                     /evalue="8.30E-06"
                     /label="ctg4_922"
                     /locus_tag="ctg4_922"
                     /protein_end="463"
                     /protein_start="64"
                     /score="24.9"
                     /tool="antismash"
                     /translation="LVFLLGAIFGKVVEMSGIAESIAKTIVNLIGSKNAMLTVVLLGAI
                     LTYSGVSLFVVVFAVYPFANQLFRQANIPKRLIPGTIALGAFTFTMDALPGTPQIQNVI
                     PTTFFGTDIYAAPFLGLIGAVFVLATGLSYLEWRRRVAARNGDGYATGIELTEAEQQQL
                     KQNLDTTSNGTTARQWLAFVPLILVAVTNKYLSTAIKEWYPNGFDFNAIGLAAYTVDVA
                     KTSAIWAVGLALIVGIIAAISFDFRRVYTGFKDGVNASIGGSLLAVMNTASEYGFGAII
                     AALPGFAIISHALGNTFTNPLVNGAVTTTVLAGVTGSASGGMSIALSAMADQYNAAILA
                     MGIPPEVMHRIVAMASGGMDTLPHNGAVITLLAVTGLTHKQSYKDIFAITIIKTIAVFV
                     "
     CDS             6318..7199
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 199.2; E-value: 1.5e-60)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_923"
                     /transl_table=11
                     /translation="MTLKQLKAFLVLARTLNYANAANELCLSQSALSLSIKTLEEELGG
                     KLFKRNTRRVEITTEGQSLIPYAKKLLANWEDMEKDVKQRFKLNRGTLNIASMPFATHA
                     VLPEVMHDFAQQHPNISFSIHDITNEKIIEKVQEGIFEIGICFEPKANDQLIFQPIFNE
                     DFLALLPKHHVLAKQKSVTWLELCSCPFVTLQNPSIIRHVIEEHCAALQVVLDLKVECH
                     QISSLSHFVAYGMGVSAIPRHFQKFIDLEKNVLVEIEDNQAQLAVGIIYKKDYELSNMS
                     SQFIETTLWHHF"
     PFAM_domain     6324..6503
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_923_0017"
                     /evalue="1.20E-17"
                     /label="ctg4_923"
                     /locus_tag="ctg4_923"
                     /protein_end="62"
                     /protein_start="2"
                     /score="63.6"
                     /tool="antismash"
                     /translation="LKQLKAFLVLARTLNYANAANELCLSQSALSLSIKTLEEELGGKL
                     FKRNTRRVEITTEGQ"
     PFAM_domain     6582..7178
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_923_0018"
                     /evalue="3.20E-35"
                     /label="ctg4_923"
                     /locus_tag="ctg4_923"
                     /protein_end="287"
                     /protein_start="88"
                     /score="121.5"
                     /tool="antismash"
                     /translation="NRGTLNIASMPFATHAVLPEVMHDFAQQHPNISFSIHDITNEKII
                     EKVQEGIFEIGICFEPKANDQLIFQPIFNEDFLALLPKHHVLAKQKSVTWLELCSCPFV
                     TLQNPSIIRHVIEEHCAALQVVLDLKVECHQISSLSHFVAYGMGVSAIPRHFQKFIDLE
                     KNVLVEIEDNQAQLAVGIIYKKDYELSNMSSQFIET"
     aSDomain        7437..8084
                     /aSDomain="TIGR02429"
                     /aSTool="tigrfam"
                     /description="pcaI_scoA_fam: 3-oxoacid CoA-transferase, A
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_924_0003"
                     /evalue="1.00E-78"
                     /identifier="TIGR02429"
                     /label="ctg4_924"
                     /locus_tag="ctg4_924"
                     /protein_end="216"
                     /protein_start="0"
                     /score="261.7"
                     /tool="antismash"
                     /translation="MNKVVANAAEALADVVANNQTVAVGGFGLCGIPEALIDALKDTGV
                     TGLTCISNNAGVDGFGLGKLLETKQIKKMIASYVGENKEFERQYLNGELEVELTPQGTL
                     AEKLRSGGAGIPAFFTQTGVGTLIAEGKEVRDFNGRPHILEMSLTADIALVKAYKADKA
                     GNLVFRKTARNFNPDCAMAGKFTIAEVEQVVEIGEIDPDDIHLPGIYINRVVL"
     CDS             7437..8141
                     /locus_tag="ctg4_924"
                     /transl_table=11
                     /translation="MNKVVANAAEALADVVANNQTVAVGGFGLCGIPEALIDALKDTGV
                     TGLTCISNNAGVDGFGLGKLLETKQIKKMIASYVGENKEFERQYLNGELEVELTPQGTL
                     AEKLRSGGAGIPAFFTQTGVGTLIAEGKEVRDFNGRPHILEMSLTADIALVKAYKADKA
                     GNLVFRKTARNFNPDCAMAGKFTIAEVEQVVEIGEIDPDDIHLPGIYINRVVLNATPKK
                     QIEQLTIKAEEA"
     PFAM_domain     7452..8087
                     /aSDomain="CoA_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01144.25"
                     /description="Coenzyme A transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_924_0019"
                     /evalue="1.40E-78"
                     /label="ctg4_924"
                     /locus_tag="ctg4_924"
                     /protein_end="217"
                     /protein_start="5"
                     /score="263.4"
                     /tool="antismash"
                     /translation="ANAAEALADVVANNQTVAVGGFGLCGIPEALIDALKDTGVTGLTC
                     ISNNAGVDGFGLGKLLETKQIKKMIASYVGENKEFERQYLNGELEVELTPQGTLAEKLR
                     SGGAGIPAFFTQTGVGTLIAEGKEVRDFNGRPHILEMSLTADIALVKAYKADKAGNLVF
                     RKTARNFNPDCAMAGKFTIAEVEQVVEIGEIDPDDIHLPGIYINRVVLN"
     CDS             8144..8791
                     /locus_tag="ctg4_925"
                     /transl_table=11
                     /translation="MAWTRNEMAQRAALELEDGFYVNLGIGLPTLVANYLPEGINVWLQ
                     SENGLLGIDEFPTRDAVDADLINAGKQTVTARKGAAFFSSSESFAMIRGGHVNIAILGA
                     MEVSETGDLANWMIPGKKVKGMGGAMDLVSGVQKVVVLMEHCAKDGTPKIVPQCTLPLT
                     GKAVVSRIITDLGVMDITAEGIKLVELARDVNLEQIQKMTGLELIINDFKAA"
     aSDomain        8150..8767
                     /aSDomain="TIGR02428"
                     /aSTool="tigrfam"
                     /description="pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_925_0004"
                     /evalue="7.90E-97"
                     /identifier="TIGR02428"
                     /label="ctg4_925"
                     /locus_tag="ctg4_925"
                     /protein_end="208"
                     /protein_start="2"
                     /score="320.6"
                     /tool="antismash"
                     /translation="WTRNEMAQRAALELEDGFYVNLGIGLPTLVANYLPEGINVWLQSE
                     NGLLGIDEFPTRDAVDADLINAGKQTVTARKGAAFFSSSESFAMIRGGHVNIAILGAME
                     VSETGDLANWMIPGKKVKGMGGAMDLVSGVQKVVVLMEHCAKDGTPKIVPQCTLPLTGK
                     AVVSRIITDLGVMDITAEGIKLVELARDVNLEQIQKMTGLELI"
     PFAM_domain     8162..8695
                     /aSDomain="CoA_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01144.25"
                     /description="Coenzyme A transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_925_0020"
                     /evalue="1.40E-41"
                     /label="ctg4_925"
                     /locus_tag="ctg4_925"
                     /protein_end="184"
                     /protein_start="6"
                     /score="142.4"
                     /tool="antismash"
                     /translation="EMAQRAALELEDGFYVNLGIGLPTLVANYLPEGINVWLQSENGLL
                     GIDEFPTRDAVDADLINAGKQTVTARKGAAFFSSSESFAMIRGGHVNIAILGAMEVSET
                     GDLANWMIPGKKVKGMGGAMDLVSGVQKVVVLMEHCAKDGTPKIVPQCTLPLTGKAVVS
                     RIITDLGVMDITAEG"
     CDS             9046..9432
                     /locus_tag="ctg4_926"
                     /transl_table=11
                     /translation="MSQQDYENGLKVRTEVMGESFVKRAQDNTVPFTQPLQDWINEHAW
                     GSTWQREGVLPRKYRSLITIAFLTAQKSPTELKGHVRGALNNGATVEEIQEVLLHSLPY
                     CGAPATQEAFRAALEVIQEYQSNS"
     PFAM_domain     9151..9399
                     /aSDomain="CMD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02627.22"
                     /description="Carboxymuconolactone decarboxylase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_926_0021"
                     /evalue="3.60E-22"
                     /label="ctg4_926"
                     /locus_tag="ctg4_926"
                     /protein_end="118"
                     /protein_start="35"
                     /score="78.3"
                     /tool="antismash"
                     /translation="LQDWINEHAWGSTWQREGVLPRKYRSLITIAFLTAQKSPTELKGH
                     VRGALNNGATVEEIQEVLLHSLPYCGAPATQEAFRAAL"
ORIGIN
        1 ttacttcatt tgcttgagca tatttttagc acctgtgtgg ttatggtttt tggctaagtt
       61 ctgcaaaaca tattttgcct gccctttagg gttggaaaaa cgactgctat aacttggaat
      121 acccgttaaa caacgtgcaa ctaatatgcc cgattcggta tagacatttg aggcatccga
      181 ccccggcaaa cgaccatagt tatatgcgcg ttgtgcactg ttacaggcag cgacttggtt
      241 gcgtccactg ttaatatcac ggcgtgcaga cacatacagt ttggcctgtt gctgctgcgg
      301 tgtttctaca gctttggcgg ctttaggtgg tacttctact ttgttttctt ttttaagctc
      361 tacttctttt ttgctttctt cctctttctt cacctctgcc ttgatcacag gtgccttcgt
      421 caccgctttt ttgcttggcg taataggggt catactccgt ggtgctggct cagtcagtac
      481 tttgctttgt agattaacca cacgagtatc atttgagtta ggcagtttgc gttcagacaa
      541 tgcctcaata ctcaccaacc actgttcacc attattgagt tggcaacgaa aagtacccgt
      601 tccctgtttt aaactgttat aggtgcgaag taactttttc gcccacggat ctttcactaa
      661 gctgaaacta cttttttgtg tctgactaaa acggccgcca tgtgcttggc aatactgact
      721 aaacatgctc cgtgggtata acgcctcgat atctttttca ttttttacgc ctaccgtgtg
      781 atacacgtat tctttgctgt ttttatcgct atcattaatt tttcgttcta cgattagttc
      841 ttgtggtgat gcaatatttt taaaaggtgc ttgtgctata tttcccagac tggtacagcc
      901 ctgcaataca ctccccaaaa ctccaaatac acataaaatt ttataattca ctacgacttt
      961 actcttaaac acccgcataa aaacattagc ggaaagctca taaaataaca aacttaaata
     1021 actgttttta ttatttattt tagtttgacg cacacatcat tctgctttgt tttatgataa
     1081 cctcaacaac attacataaa tttaatttga accacacaac aaaagttaca gacaaaacga
     1141 tgcttgagca cataaaaaac ctgccgttaa aggcaggtta aatacatcaa aaatatttag
     1201 tcatccaaag tcgcttcaaa agctttcaga cgcttataaa tcgagagcag ttcgataata
     1261 gttggccatg atgcaatcaa atactgaaat gactctcgga ctttgccaaa aacatttgcg
     1321 atttgcatca tcaaacctaa ggtgatcgca cccgcggcaa tacttggaaa taaaacaaat
     1381 aaaccataaa tattgtcaag ttgcatatac caaatacgca ctaagttaaa ataagcatag
     1441 tggaaatata ggcggaaata gttaagacgt actttgctaa acagctcttt taaactcact
     1501 ggatcagcac gttcagcatg atcttcgcca tacaccaact cttttcgata tgctgcttcg
     1561 actttttgat tattaaactc taaacctggt aatttagcac caacgaccat cagcacaact
     1621 gtaccaaaca cagcccaacc tactgccgcc caaaccaatg catgcggaat ttcacctacc
     1681 acaggcaaag ctttgacatg catagataag ctaaataaca caggtaaaaa tgcaatgaga
     1741 gtcattaacg cttcaaccaa gttcaccccc aaactttcag tggttttggc aaagcgcatg
     1801 gtgtcttctt gaatacgctg tgatgccccc tcaatgtgtc gtagtttttc ccaatgctca
     1861 gtgtaatatt cattcattgc agtacgccaa cggaacacat aatggctgac gaaaaataaa
     1921 tttagcacca ttaaagtcac ggccaccatt gccacataca aaaaggtcag gacacctgta
     1981 taaagggtgt tgacgtctcc gcccccatta ctcaacattt cttggattaa gtcataaaaa
     2041 gggttatacc aagcatttac aacgacactg acctgtacac caaaccaaat gttaaacaag
     2101 atgaatgctg atccccatac cgaccaacgc tgccatttat tgtcagaaaa aaaacgccaa
     2161 aataaggcaa acaagcaggt cgaaacaaag aaccacaaat aaaaccataa aaaagcgggc
     2221 gaccaaaaac ggcttactcc aatgactaaa tcagcttcag cataacctgc aggaaagcca
     2281 atccaactac cccatccact gccacccgaa taccataaag aaagattgac aataaaccac
     2341 acaatcaatg agataaaaaa ccatctaggg tttgggaaaa atgacttaaa catgaacgat
     2401 atatatccct tttatatttc aggtatgcaa tccgtgcata ctaatcctta tttcttaatt
     2461 tagtaaaatc gcattacagc aagtttgtac actttactta tccttatttg gttatacgtt
     2521 atttgatttg tatgcccctt cacaagagct caggacatta ttttccgact tgatcagtca
     2581 catcacaatc aaaataaatt atttcaataa cttatgaaaa taggaaagga cttggcccca
     2641 gatttaaaat aatattttat tgcttataac ttttgggttt caaactgaaa aattgcttag
     2701 gatttaaagc gagtgcaatg acggtatttc tctgacaacc atacgattac ttgttgattt
     2761 tatgtataaa agaatgaagt ttgcacattt taaaatgact tcatgctact atcttttcat
     2821 taaaaactat tggatctatg acatggaaac cctagtactt gaactgatca aaccactcac
     2881 actgacaaaa gaagactttc cacccattaa ctttgaagaa ggcactgtgc tcaaagttct
     2941 catgaaaaca cctacaggtt acttggtaac ggcggactct cgttttaatt ttacggtgtc
     3001 ttttgatgat gaaaatcaag tatggcagaa gctgtaattt gcaatgctct ttaataaaag
     3061 aataatccat tcaataagat aaaaataaaa tccatctttt tttattgatt taaaactgat
     3121 tatttttatt aaaatttaat tttttatacc gaatcagcaa atgaataccg tactgagagt
     3181 tttctgtacc tattgatttt gtgatttcta gggctcattt gtagcatcgt tatgcattca
     3241 ttttctcctt aatctattga tttaattact ctacactaag tctttcatcc ttagtattta
     3301 aaacattgaa ctataaatca gaaaaagaga aaggatttga aaatcttcag tctataaatc
     3361 tatatttacc gactcattca tcaagctcac cacttattta aacctaggtc tttctgcaaa
     3421 atctatcgct ataaaaaaag ccccagatac gaacatccaa ggcttctcaa tttttaaatc
     3481 tatgctgagc taagttattg cgcggtataa ccaccatcca tcaccacggc ttgaccagtt
     3541 ataccgcccg ccttatcact ggcaaggaag attgcataat ccgcaatttc ttctacactg
     3601 agtaagcgtt tttgcggcac catcgccaaa atcacatctt ctaatgcact ttgctcactg
     3661 acatttcggg ttttagccaa gtcatgaatt tgaccacgta ccaacggcgt atcgacatag
     3721 cccggacaca gagcattcac ggtgatgcca tcgcgcgcgc actctaaagc cgcaactttg
     3781 gtcaaaccaa ttacaccatg cttagcactg ttatagccgg ccttgccagc aaaaccgatc
     3841 agaccgttaa tcgaagccat attaatcacg cgaccaaact gctgcgcttt catgattgga
     3901 aatacgtact taatgccaat gaacgacccc accaacatga cattaatcag cttttgatag
     3961 actgcagttg gaaagtcttc aatcactgca acatgctgaa aacccgcatt attgatgagg
     4021 atgtccaacc gcccataggt tttctgagtc agttcaattg ctgttttata tgcctcttca
     4081 ttggtcacat cgcaaggcgc agacaatgct tcaaagcctt gcttttgaag tgccgccacc
     4141 gtttcagcac acttctctgc attcatatca gaaatgacaa cttttgcacc ttcactggca
     4201 aatttctttg caatttcatg tccaatacca ctggctgaac cggtaataaa tgcaacttta
     4261 tcttttaaca gttgactcat gatgtactcc gttgtcttct tttttcattc caaagtctta
     4321 aacaatacca aaccaagtaa aggcagcaat ggcaacaaat accgcgatgg ttttaataat
     4381 cgtgatggca aaaatatctt tataagattg tttatgggtt aaacctgtga ccgcaagtaa
     4441 ggtaatcacg gcgccgttat gcggtaaggt atccatacca ccagatgcca tcgcaacaat
     4501 acggtgcatc acttcaggtg gaatacccat ggctaaaatc gcagcattgt actgatccgc
     4561 catcgcactt aaagcgatac tcataccgcc agaggctgaa ccagtcacac ccgctaagac
     4621 tgtcgtggta accgcaccat tgaccagtgg attggtaaaa gtattgccca atgcatggct
     4681 aataatcgca aagcccggta aggccgcaat aatcgcacca aaaccatatt cagatgcggt
     4741 attcatcacg gcaagtaaag acccgccaat actggcattg acaccatctt tgaagcccgt
     4801 atagacacga cggaagtcaa atgaaattgc cgcgataatg cccacaatta aggctaaacc
     4861 cacggcccaa atggcagagg ttttcgcaac atcgacggtg taagctgcaa gtccaatggc
     4921 attgaaatca aaaccgtttg gataccattc tttaattgca gtggataaat acttattggt
     4981 cacggcaact aaaatgaggg gtacaaaagc caaccattga cgtgcggtag taccattcga
     5041 ggttgtatct aagttttgct tcagttgttg ttgctcagct tctgtcagct caatgcctgt
     5101 ggcataacca tcgccatttc gagcagctac acggcgacgc cattccaaat agctcaaacc
     5161 tgtagcaaga acaaataccg caccaatcaa accaagaaac ggcgctgcat aaatatctgt
     5221 accaaaaaag gtcgtcggaa taacgttttg aatctgcggg gttcccggca aggcatccat
     5281 ggtaaaggta aatgcaccaa gggcaatggt tcccggaatc aaacgctttg gaatgttggc
     5341 ttgtctaaaa agttgatttg caaatggata aactgcaaag accaccacaa agagactgac
     5401 accgctatag gttaaaatcg cccctaaaag cacaacggtt aacattgcat ttttagagcc
     5461 aatcaggttc acaatggttt tggcaatgga ttctgcaatc cctgacattt caaccacttt
     5521 accgaagatg gcaccgagta aaaacaccaa gaaataatct ttaatgaacc caaccatttt
     5581 gggcataaat acgcctgaat aaaaaggcaa aacgttagca gggttaatca gtaaaactgc
     5641 caacagggca caaatcggtg ccataagaat tacagaaaaa cctctgtagg ctgtatacat
     5701 cagtagccca agagacaata aaattacacc caaatcccac atatttttta ctccatcctt
     5761 aaagaaaata tgtcttgatg tgctgtgata ttaatggcga atgatgtcaa atctagttga
     5821 gtcacagtgc aatcagcctg tgcggaaaga ccgaatacgc attcatagac cgtctatttt
     5881 ccctcatgac gagatgtcta tttgcactct gatctatgta ctatatttat ccatcagagc
     5941 attaatattt cagcttatgg gtcagactat aatgcatata aacccacgca ttgtttaaaa
     6001 ataatcattg agtaagaaga aaaattgatt aatatccaag ccctagcaag actgataaaa
     6061 ctaattgcat caagttaaag gtaaaatttc aaaatcgcac gaaatgacca atttttatat
     6121 ttttcattca gttaaaacat atttttacag actatcatgc tcttcgactt atactgcttt
     6181 gacgacttga taaaaatgca cccacttcca tcacttgatc tgttttgacc gtctgttgta
     6241 tttttcatgt aaaccatttg agaacagcac gtttattttc tttcaacatc gtgttgcatc
     6301 attgctcagg gaagctcatg acactcaaac aattaaaagc ctttttggtc cttgcacgta
     6361 cgcttaatta tgccaatgca gccaatgaac tgtgtctgag ccaatccgct cttagcttaa
     6421 gcattaaaac attagaagaa gaactgggtg gaaaactgtt taaacgcaac acgcgccgag
     6481 tagaaatcac cactgaaggt cagtccctca ttccctatgc caaaaaactc ttggccaact
     6541 gggaggatat ggaaaaagat gtcaaacagc gctttaaact caaccgtggc actttaaata
     6601 ttgcctcaat gccctttgcc actcatgcgg tactccccga agtgatgcat gattttgcac
     6661 agcagcaccc caacatcagt ttttcaatcc atgacatcac caatgaaaaa atcattgaaa
     6721 aagttcaaga aggcattttt gagattggca tttgttttga acccaaggcc aatgaccaac
     6781 tgatttttca gcctatattc aatgaagact ttttagctct cttgcccaaa caccacgtct
     6841 tagccaaaca aaaaagcgtg acatggcttg aactctgctc ttgtccattt gtgaccttac
     6901 aaaacccctc gattattcgc catgtgattg aggaacattg tgctgcgctt caagtggtgt
     6961 tggacttgaa agtcgaatgc caccaaatca gttcgctttc acattttgtt gcctacggta
     7021 tgggcgtgag tgctattcca cgacacttcc aaaaattcat cgatcttgaa aaaaatgtgt
     7081 tggttgaaat tgaggacaac caagcgcaac tcgcggtggg cattatttat aaaaaagatt
     7141 atgaactgtc taacatgtcg tctcaattta ttgaaaccac actttggcat catttctaag
     7201 ctaagctctc cccccttctc tgggcgaaac tgaagctaaa ccttgatagc tcagaataag
     7261 ccgtatgatt atttgcatgg ctttaccaca tgctttgact cttcttttat ttatttttct
     7321 tcgtaaatat tctacattaa tgagtttttc ttattatacg ttagaaagat tcaatttcta
     7381 aaaagtacag cgcaatgcta aaaaaataac aagcaaggaa gatcaggaaa taaaacatga
     7441 ataaagtcgt cgcaaatgca gccgaagcat tagctgatgt agttgccaat aatcaaacgg
     7501 ttgccgtggg tggttttggc ctctgtggta ttccagaagc attaattgat gccttaaaag
     7561 atacaggtgt cacaggttta acctgtattt cgaataatgc aggtgtggat ggcttcggtt
     7621 taggtaaatt attagaaacc aaacaaatta aaaaaatgat tgcctcttat gtcggtgaaa
     7681 ataaagagtt tgagcgacag tatctcaatg gcgaacttga agttgagctt actccacaag
     7741 gtacactcgc agaaaaacta cgttcaggtg gcgcaggtat tcctgcattt ttcacccaaa
     7801 caggtgtagg caccctcatt gccgaaggta aagaagtccg cgactttaat ggtcgtccgc
     7861 atattttaga aatgtccctt actgcggaca ttgctttagt gaaagcctac aaagccgata
     7921 aagcagggaa cttagtgttc cgtaaaacag ctcgtaactt taaccctgac tgtgccatgg
     7981 caggcaaatt caccattgcc gaagttgaac aggtggttga aattggtgaa atcgatccag
     8041 atgacatcca tttaccgggt atctacatca accgtgtggt actgaacgcc accccaaaaa
     8101 agcagatcga acaactgacc attaaagcag aggaagctta atcatggctt ggacacgtaa
     8161 tgaaatggcg cagcgtgctg cccttgaact cgaagatggt ttttatgtca acttaggtat
     8221 tggcttgccg actttagtgg ccaattatct gccagaaggg atcaatgttt ggttacagtc
     8281 agaaaatggc ttgctcggta ttgatgaatt tccaacccgt gatgccgtcg atgcagactt
     8341 gattaatgca ggaaaacaaa ccgtcaccgc acgtaaagga gctgcatttt tctcaagctc
     8401 agaatctttt gccatgattc ggggtggtca tgtcaatatt gctattttag gcgcaatgga
     8461 agtctctgaa acaggcgact tggcaaactg gatgattccg ggtaaaaaag tcaaaggcat
     8521 gggcggtgca atggacttgg tctctggtgt acaaaaagtt gtggttctga tggaacactg
     8581 cgccaaagat ggcacgccaa aaatcgtgcc ccaatgtacc ctaccactca cgggtaaagc
     8641 tgtcgtcagc cgtatcatta ctgacttagg cgtgatggat atcactgctg aaggtataaa
     8701 actggttgaa ctggcacgcg atgtgaacct agaacaaatc caaaaaatga ctggattaga
     8761 actcatcatc aatgacttta aagccgctta gtacaaaacg acatcattca aagcagcttc
     8821 ggctgctttc ttattgggct caatcaaaaa gattttcagt tagaaagaga cttctttata
     8881 gcctttgaat caagcataaa aaccatcatc agcttgatta agagtatctt tatactcccg
     8941 aatttagcga atgatgactc ccgcgcacat cttttcaacc caaatacctg atgaaaaacc
     9001 aaaccgctcg gctactatat ttgcactcca cattcagagg tttccatgtc acaacaagat
     9061 tatgaaaatg gtttaaaagt tcgcacagaa gtcatgggcg aatcttttgt taaacgtgct
     9121 caggacaata ctgtaccttt cacccaacct ttgcaggact ggattaatga acatgcttgg
     9181 ggctcaacat ggcaacgtga aggtgtctta ccacgtaaat atcgctcgtt aattaccatt
     9241 gcatttttga cggcacaaaa aagtccaact gagctgaaag gtcacgttcg tggtgcgttg
     9301 aataacggtg caacggttga agaaattcaa gaagtccttt tacacagttt gccttattgc
     9361 ggcgcacctg cgactcaaga ggctttccgt gctgcgctgg aagtgattca ggaatatcaa
     9421 agcaactcat aa
//
