LOCUS       c00012_NZ_QROT..       20585 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_QROT01000002.1 Eubacterium ventriosum strain AF37-4 AF37-4.Scaf2,
            whole genome shotgun sequence.
ACCESSION   NZ_QROT01000002
VERSION     NZ_QROT01000002
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:49:22
            Original ID  :: NZ_QROT01000002.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 164935
            Orig. end    :: 185520
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20585
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[174935:175520](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10585)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20585
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20585
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             849..2060
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 101.5; E-value:
                     7.6e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_136"
                     /transl_table=11
                     /translation="MNKRVTQAVILAGGLGTRLKPFTNTNPKPMYPINNVPFIDYLIRQ
                     MKNFGMEEVLLLLGYLPEKIMDYLGDGSRYGLTINYNITPVDYDTGMRIKHAAPQIADT
                     FFLLYCDNYCPINYLKLFSDFCNNKAKIQITVYSNRDNYTKNNLHITDDGLVTTYDKKR
                     IRSNLQGVDIGYALVDKSVISLLPEENCNFESEIYTQLVQKKEIFATVTEHRYYSVGSF
                     ERIKLTREFFKPKRVVFLDRDGTINKRPKQACYVEKPEDFIWLPGALEAIRLLKNNGFL
                     VIVITNQPGIARGNLTEEMLYCIHAKMHMELLKAETEIDDILYCPHNWNEGCFCRKPSP
                     GMLYEAQKKYELNLSECYLIGDDERDIEAGTIAGCKCRMVDEKHTILDVVKEIVALEKK
                     GEDT"
     PFAM_domain     870..1268
                     /aSDomain="NTP_transferase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00483.25"
                     /description="Nucleotidyl transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_136_0001"
                     /evalue="5.20E-14"
                     /label="ctg12_136"
                     /locus_tag="ctg12_136"
                     /protein_end="140"
                     /protein_start="7"
                     /score="52.5"
                     /tool="antismash"
                     /translation="AVILAGGLGTRLKPFTNTNPKPMYPINNVPFIDYLIRQMKNFGME
                     EVLLLLGYLPEKIMDYLGDGSRYGLTINYNITPVDYDTGMRIKHAAPQIADTFFLLYCD
                     NYCPINYLKLFSDFCNNKAKIQITVYSNR"
     aSDomain        1554..1982
                     /aSDomain="TIGR01662"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IIIA: HAD hydrolase, family IIIA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_136_0002"
                     /evalue="1.20E-29"
                     /identifier="TIGR01662"
                     /label="ctg12_136"
                     /locus_tag="ctg12_136"
                     /protein_end="378"
                     /protein_start="235"
                     /score="101.2"
                     /tool="antismash"
                     /translation="RVVFLDRDGTINKRPKQACYVEKPEDFIWLPGALEAIRLLKNNGF
                     LVIVITNQPGIARGNLTEEMLYCIHAKMHMELLKAETEIDDILYCPHNWNEGCFCRKPS
                     PGMLYEAQKKYELNLSECYLIGDDERDIEAGTIAGCKCR"
     PFAM_domain     1557..1934
                     /aSDomain="PNK3P"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08645.13"
                     /description="Polynucleotide kinase 3 phosphatase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_136_0002"
                     /evalue="1.20E-10"
                     /label="ctg12_136"
                     /locus_tag="ctg12_136"
                     /protein_end="362"
                     /protein_start="236"
                     /score="41.4"
                     /tool="antismash"
                     /translation="VVFLDRDGTINKRPKQACYVEKPEDFIWLPGALEAIRLLKNNGFL
                     VIVITNQPGIARGNLTEEMLYCIHAKMHMELLKAETEIDDILYCPHNWNEGCFCRKPSP
                     GMLYEAQKKYELNLSECYLIGD"
     aSDomain        1557..1979
                     /aSDomain="TIGR01656"
                     /aSTool="tigrfam"
                     /description="Histidinol-ppas: histidinol-phosphate
                     phosphatase domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_136_0001"
                     /evalue="2.90E-37"
                     /identifier="TIGR01656"
                     /label="ctg12_136"
                     /locus_tag="ctg12_136"
                     /protein_end="377"
                     /protein_start="236"
                     /score="125.8"
                     /tool="antismash"
                     /translation="VVFLDRDGTINKRPKQACYVEKPEDFIWLPGALEAIRLLKNNGFL
                     VIVITNQPGIARGNLTEEMLYCIHAKMHMELLKAETEIDDILYCPHNWNEGCFCRKPSP
                     GMLYEAQKKYELNLSECYLIGDDERDIEAGTIAGCKC"
     CDS             2057..3043
                     /locus_tag="ctg12_137"
                     /transl_table=11
                     /translation="MIISKTPLRASFFGGGTDFSTYYENSKLGYGTVVSTALDMYVYIT
                     VNKKFDDSIRIVYSDNELVSNVDEVKHNIIREALKIVGIERGIEIVYMADIPLSNAGIG
                     LASSSALAVGVLNALHVYKGEFVSQGVLAREACEIEINRLGQRIGIQDQFAVAHGGFNQ
                     YKFFSNGSVSVSPIVCRKDIVENLKKNLMLFYTGNTRDSREILNEQSDTIVEKTVMLDD
                     LVNTTDCAVRALYDGNIDYWGTELDRTWNIKKKFAKGISNLLIDEMYNKAKSAGAIGGK
                     ILGAGGGGFMLLYVPQKKQDSVKKELADFRNIPFSCSNEGSKIVFYD"
     PFAM_domain     2360..2536
                     /aSDomain="GHMP_kinases_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00288.28"
                     /description="GHMP kinases N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_137_0003"
                     /evalue="5.60E-06"
                     /label="ctg12_137"
                     /locus_tag="ctg12_137"
                     /protein_end="160"
                     /protein_start="101"
                     /score="26.6"
                     /tool="antismash"
                     /translation="GIGLASSSALAVGVLNALHVYKGEFVSQGVLAREACEIEINRLGQ
                     RIGIQDQFAVAHGG"
     PFAM_domain     2750..2977
                     /aSDomain="GHMP_kinases_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08544.15"
                     /description="GHMP kinases C terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_137_0004"
                     /evalue="2.00E-05"
                     /label="ctg12_137"
                     /locus_tag="ctg12_137"
                     /protein_end="307"
                     /protein_start="231"
                     /score="25.0"
                     /tool="antismash"
                     /translation="RALYDGNIDYWGTELDRTWNIKKKFAKGISNLLIDEMYNKAKSAG
                     AIGGKILGAGGGGFMLLYVPQKKQDSVKKEL"
     CDS             3058..3675
                     /locus_tag="ctg12_138"
                     /transl_table=11
                     /translation="MDYRKLIKSYIENEIETINKIDMDQINAALNLLEAGIKREATVYV
                     FGNGGSAATASHIQNDFNKGISEHTKEKFRFLCLNDNIATVMAIANDIGYEEIFRFQLI
                     GKIKSNDIIVAISGSGNSKNVINAVEYGKNHGCKVIGMTGYSGGKLKELADISLHSPIN
                     SMQITEDIHMIFNHLMMSIFYKTMCGINHIKNKGDTDEQNIY"
     PFAM_domain     3088..3489
                     /aSDomain="SIS_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13580.8"
                     /description="SIS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_138_0005"
                     /evalue="2.80E-23"
                     /label="ctg12_138"
                     /locus_tag="ctg12_138"
                     /protein_end="144"
                     /protein_start="10"
                     /score="82.5"
                     /tool="antismash"
                     /translation="IENEIETINKIDMDQINAALNLLEAGIKREATVYVFGNGGSAATA
                     SHIQNDFNKGISEHTKEKFRFLCLNDNIATVMAIANDIGYEEIFRFQLIGKIKSNDIIV
                     AISGSGNSKNVINAVEYGKNHGCKVIGMTG"
     CDS             3656..4678
                     /NRPS_PKS="Domain: NAD_binding_4 (49-186). E-value:
                     1.6e-12. Score: 38.9. Matches aSDomain:
                     nrpspksdomains_ctg12_139_NAD_binding_4.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     197.3; E-value: 6.4e-60)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_139"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.5e-20,
                     bitscore: 67.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.1e-21, bitscore:
                     69.9, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKIFISGAAGFIGSQLSYYLFKKGYHVTLLDNFSYGVEDNLIFP
                     DCDFRGKIIRGDIRDKNLIDELFKKNKFDYVYHIAAITPLPDCQINPIEAVDVNITGTL
                     TILEASRTYGVKKLVFASTSAVYENNEKFPLFEENPVRPNLIYPSTKYAAEQFCYDYVK
                     NYDMNITCLRFANVYGPHIDCLRKQPPVVGYIIRELFYDRSPILHSTGNQSRDFVYVED
                     LISLCEMVLNGKGFDIVNVSSGISVSINELMLMISKLMNREEINAIYKGEAFFWKKYPE
                     LYKKPYPIKNEVLVHEVKKYTNLSNKHAFERYGWKPQTSMEEGLKRTISFVCEMLEKHC
                     "
     PFAM_domain     3665..4354
                     /aSDomain="Epimerase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01370.23"
                     /description="NAD dependent epimerase/dehydratase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_139_0006"
                     /evalue="5.10E-52"
                     /label="ctg12_139"
                     /locus_tag="ctg12_139"
                     /protein_end="233"
                     /protein_start="3"
                     /score="176.8"
                     /tool="antismash"
                     /translation="IFISGAAGFIGSQLSYYLFKKGYHVTLLDNFSYGVEDNLIFPDCD
                     FRGKIIRGDIRDKNLIDELFKKNKFDYVYHIAAITPLPDCQINPIEAVDVNITGTLTIL
                     EASRTYGVKKLVFASTSAVYENNEKFPLFEENPVRPNLIYPSTKYAAEQFCYDYVKNYD
                     MNITCLRFANVYGPHIDCLRKQPPVVGYIIRELFYDRSPILHSTGNQSRDFVYVEDLIS
                     LCEMVLNG"
     aSDomain        3803..4213
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_139_NAD_binding_4.1"
                     /evalue="1.60E-12"
                     /label="ctg12_139_NAD_binding_4.1"
                     /locus_tag="ctg12_139"
                     /protein_end="186"
                     /protein_start="49"
                     /score="38.9"
                     /tool="antismash"
                     /translation="RGKIIRGDIRDKNLIDELFKKNKFDYVYHIAAITPLPDCQINPIE
                     AVDVNITGTLTILEASRTYGVKKLVFASTSAVYENNEKFPLFEENPVRPNLIYPSTKYA
                     AEQFCYDYVKNYDMNITCLRFANVYGPHIDCLR"
     CDS             4734..5909
                     /locus_tag="ctg12_140"
                     /transl_table=11
                     /translation="MEKRLFTSESVTEGHPDKICDQIADAILDEYMKKDVNSKVACEVA
                     ITTDFVLIMGEITSNAKVNIDKIVRDTIRDIGYDNVEYGFDCDNCNVIINIDEQSTDIA
                     LGVDKYKLDKVNKSSDLIGAGDQGMMFGYATDETSEMMPYPIYLAHKLTKRLTEVRKNG
                     ILKYLRPDGKSQVTVEYDSDDKPVRIEAVVISTQHNSEISQEQLHKDIRKYVIDSTIPP
                     NMVDSKTKYYINPTGRFVIGGPHGDSGLTGRKIIVDTYGGYARHGGGAFSGKDCTKVDR
                     SAAYMARYVAKNIVAARLAEKCEIQLSYAIGVTEPISISVNTFGTGKVSDSKLIQIIRN
                     KFDLSPYGIIKFFDLRRPIYRQVAAYGHFGRNELELPWEKTDKVSEIIKEL"
     PFAM_domain     4743..5033
                     /aSDomain="S-AdoMet_synt_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00438.22"
                     /description="S-adenosylmethionine synthetase, N-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_140_0007"
                     /evalue="1.90E-41"
                     /label="ctg12_140"
                     /locus_tag="ctg12_140"
                     /protein_end="100"
                     /protein_start="3"
                     /score="140.7"
                     /tool="antismash"
                     /translation="RLFTSESVTEGHPDKICDQIADAILDEYMKKDVNSKVACEVAITT
                     DFVLIMGEITSNAKVNIDKIVRDTIRDIGYDNVEYGFDCDNCNVIINIDEQS"
     aSDomain        4746..5894
                     /aSDomain="TIGR01034"
                     /aSTool="tigrfam"
                     /description="metK: methionine adenosyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_140_0003"
                     /evalue="2.50E-179"
                     /identifier="TIGR01034"
                     /label="ctg12_140"
                     /locus_tag="ctg12_140"
                     /protein_end="387"
                     /protein_start="4"
                     /score="594.0"
                     /tool="antismash"
                     /translation="LFTSESVTEGHPDKICDQIADAILDEYMKKDVNSKVACEVAITTD
                     FVLIMGEITSNAKVNIDKIVRDTIRDIGYDNVEYGFDCDNCNVIINIDEQSTDIALGVD
                     KYKLDKVNKSSDLIGAGDQGMMFGYATDETSEMMPYPIYLAHKLTKRLTEVRKNGILKY
                     LRPDGKSQVTVEYDSDDKPVRIEAVVISTQHNSEISQEQLHKDIRKYVIDSTIPPNMVD
                     SKTKYYINPTGRFVIGGPHGDSGLTGRKIIVDTYGGYARHGGGAFSGKDCTKVDRSAAY
                     MARYVAKNIVAARLAEKCEIQLSYAIGVTEPISISVNTFGTGKVSDSKLIQIIRNKFDL
                     SPYGIIKFFDLRRPIYRQVAAYGHFGRNELELPWEKTDKVSEI"
     PFAM_domain     5097..5450
                     /aSDomain="S-AdoMet_synt_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02772.18"
                     /description="S-adenosylmethionine synthetase, central
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_140_0008"
                     /evalue="1.30E-50"
                     /label="ctg12_140"
                     /locus_tag="ctg12_140"
                     /protein_end="239"
                     /protein_start="121"
                     /score="170.7"
                     /tool="antismash"
                     /translation="IGAGDQGMMFGYATDETSEMMPYPIYLAHKLTKRLTEVRKNGILK
                     YLRPDGKSQVTVEYDSDDKPVRIEAVVISTQHNSEISQEQLHKDIRKYVIDSTIPPNMV
                     DSKTKYYINPTGRF"
     PFAM_domain     5454..5873
                     /aSDomain="S-AdoMet_synt_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02773.18"
                     /description="S-adenosylmethionine synthetase, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_140_0009"
                     /evalue="1.80E-70"
                     /label="ctg12_140"
                     /locus_tag="ctg12_140"
                     /protein_end="380"
                     /protein_start="240"
                     /score="235.4"
                     /tool="antismash"
                     /translation="IGGPHGDSGLTGRKIIVDTYGGYARHGGGAFSGKDCTKVDRSAAY
                     MARYVAKNIVAARLAEKCEIQLSYAIGVTEPISISVNTFGTGKVSDSKLIQIIRNKFDL
                     SPYGIIKFFDLRRPIYRQVAAYGHFGRNELELPWEK"
     CDS             6032..6352
                     /locus_tag="ctg12_141"
                     /transl_table=11
                     /translation="MEKETNAGTRVRYARELNHFTREELAEYAGISTKFLYEIENNHKG
                     MSAHTLLNICKALDVSCDYIMTGGGDYTCDQEVITIIESFDASQIPNVKKILTELLELS
                     KY"
     PFAM_domain     6062..6226
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_141_0010"
                     /evalue="3.30E-10"
                     /label="ctg12_141"
                     /locus_tag="ctg12_141"
                     /protein_end="65"
                     /protein_start="10"
                     /score="39.9"
                     /tool="antismash"
                     /translation="VRYARELNHFTREELAEYAGISTKFLYEIENNHKGMSAHTLLNIC
                     KALDVSCDYI"
     CDS             6602..6919
                     /locus_tag="ctg12_142"
                     /transl_table=11
                     /translation="MNYMHSSEKIKGLRIHQGYTVEQLAEEANISTKFLYEIEAGRKGF
                     SANVLYKISKALNVSCDYILNDSNQQTVPDFIIELVKKLDSKEQVAVEHILVEIIRLRE
                     E"
     PFAM_domain     6629..6793
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_142_0011"
                     /evalue="6.10E-12"
                     /label="ctg12_142"
                     /locus_tag="ctg12_142"
                     /protein_end="64"
                     /protein_start="9"
                     /score="45.5"
                     /tool="antismash"
                     /translation="IKGLRIHQGYTVEQLAEEANISTKFLYEIEAGRKGFSANVLYKIS
                     KALNVSCDYI"
     CDS             6944..7282
                     /locus_tag="ctg12_143"
                     /transl_table=11
                     /translation="MKYDYLDYEQIKKMGERIKISRKSNNMTQSELADILGISADQVSN
                     IELGKSACKIDHIYLLMQVLDISADYLFGNFVNTNVVRVTDEQIINMATKTNKKMKMII
                     YELLMLMA"
     PFAM_domain     6995..7159
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_143_0012"
                     /evalue="1.80E-11"
                     /label="ctg12_143"
                     /locus_tag="ctg12_143"
                     /protein_end="72"
                     /protein_start="17"
                     /score="44.0"
                     /tool="antismash"
                     /translation="IKISRKSNNMTQSELADILGISADQVSNIELGKSACKIDHIYLLM
                     QVLDISADYL"
     CDS             7431..7817
                     /locus_tag="ctg12_144"
                     /transl_table=11
                     /translation="MDKKMISRKDRQKAKRLKSVRDRQHLTQEKMAERLDISYSTYQRM
                     ESGRNNITIEHLEKLHKEFGVSSDYILFGTVNDEKHYELELEYMNDKTKFLMVTRLIAC
                     LCRLDENKYKELMIKLEKDLKEIQ"
     PFAM_domain     7479..7643
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_144_0013"
                     /evalue="1.90E-15"
                     /label="ctg12_144"
                     /locus_tag="ctg12_144"
                     /protein_end="71"
                     /protein_start="16"
                     /score="56.7"
                     /tool="antismash"
                     /translation="LKSVRDRQHLTQEKMAERLDISYSTYQRMESGRNNITIEHLEKLH
                     KEFGVSSDYI"
     CDS             7828..8571
                     /locus_tag="ctg12_145"
                     /transl_table=11
                     /translation="MRMNTSDKQILIVEDNNKNMEKLCEVLKDIKDVYIHKAKNSEQAY
                     RYALEYNIDLFIVDIILNTKVFADISGLKFIESIRSINGYKFTPIIVTTSLEDPKFHAY
                     SNLHCFRYYEKPYDYAEFKKSVVEALEYTTPKKAKDFYYYKDDGVIYSIKTKNIVYFQT
                     NNRITYIKCKNGKVMPTPYKSNKKILLELNSKKFLRCSNNTIVNAEYIEGIDKSNRYVM
                     LVDGFGTLEIGPKLKKKFLEDFFKC"
     PFAM_domain     7855..8202
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_145_0014"
                     /evalue="5.40E-12"
                     /label="ctg12_145"
                     /locus_tag="ctg12_145"
                     /protein_end="125"
                     /protein_start="9"
                     /score="46.0"
                     /tool="antismash"
                     /translation="ILIVEDNNKNMEKLCEVLKDIKDVYIHKAKNSEQAYRYALEYNID
                     LFIVDIILNTKVFADISGLKFIESIRSINGYKFTPIIVTTSLEDPKFHAYSNLHCFRYY
                     EKPYDYAEFKKS"
     PFAM_domain     8275..8505
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_145_0015"
                     /evalue="2.70E-09"
                     /label="ctg12_145"
                     /locus_tag="ctg12_145"
                     /protein_end="226"
                     /protein_start="149"
                     /score="37.2"
                     /tool="antismash"
                     /translation="IYSIKTKNIVYFQTNNRITYIKCKNGKVMPTPYKSNKKILLELNS
                     KKFLRCSNNTIVNAEYIEGIDKSNRYVMLVDG"
     CDS             8565..9812
                     /locus_tag="ctg12_146"
                     /transl_table=11
                     /translation="MLERIYWLLEIISLAICISSIYGVKIKADIKTVAWIAIEVMFMGM
                     FKRNLITMQTYFIIYVLYILYVYIEFRMSLKIATFTAILSMIFTGLIQMIIALPVYYIG
                     DYCKTSENIMVLVINAGVLMAVVLISKTKFLHGVYKFLARKELILNITFILVMFIYGYC
                     MYRIKYSNKIQSDLYVIIVTFASIIACILLRWKVMERETEYQQEQIKLSNRYSEEYNAL
                     VEISRKKQHDFKNQINALYGLSDIKAEKEQRKYIDKLLDENKVVKILHSVEQPVLAGFL
                     YRKVNEIMAAGINIEFNLSVPDAELAIEVFDCIEIVGILLDNAVEALNKEKDKSIILEM
                     FTMEQKVEIRVKNVSPYYENDEISKFFQYNYSTKGKNRGIGLAKIKDLQKKYKFDILVE
                     MQEIHNKNWISFSVIK"
     PFAM_domain     9489..9767
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_146_0016"
                     /evalue="3.80E-13"
                     /label="ctg12_146"
                     /locus_tag="ctg12_146"
                     /protein_end="401"
                     /protein_start="308"
                     /score="49.3"
                     /tool="antismash"
                     /translation="EVFDCIEIVGILLDNAVEALNKEKDKSIILEMFTMEQKVEIRVKN
                     VSPYYENDEISKFFQYNYSTKGKNRGIGLAKIKDLQKKYKFDILVEMQ"
     CDS             complement(9871..10011)
                     /locus_tag="ctg12_147"
                     /transl_table=11
                     /translation="MFRKKLSLSCMNKICGSCLALMSFIHFSGISFLLFGERKFPTPIE
                     H"
     CDS             complement(10001..10585)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_148"
                     /sec_met_domain="AgrB (E-value: 8.8e-25, bitscore: 81.3,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKIRQALKTTYNYSDYELELVKYTLLSIASEFSKILLLYIFYII
                     IGKVLSFTVFILLLSLIRFNSGGFHCKHYTTCLLLTFVISYLAVVILPQLITPDILFIQ
                     FFTIVCILINYYIGPIVSPLRPSPNSVLLKHCQNNSFLIIFAFFIIVSIFNSHSIIYPY
                     LIIGFWTIILHTCQMMFAKILIIKGGLKNVS"
     PFAM_domain     complement(10052..10582)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_148_0017"
                     /evalue="4.40E-23"
                     /label="ctg12_148"
                     /locus_tag="ctg12_148"
                     /protein_end="178"
                     /protein_start="1"
                     /score="81.7"
                     /tool="antismash"
                     /translation="DKIRQALKTTYNYSDYELELVKYTLLSIASEFSKILLLYIFYIII
                     GKVLSFTVFILLLSLIRFNSGGFHCKHYTTCLLLTFVISYLAVVILPQLITPDILFIQF
                     FTIVCILINYYIGPIVSPLRPSPNSVLLKHCQNNSFLIIFAFFIIVSIFNSHSIIYPYL
                     IIGFWTIILHTCQM"
     CDS             10840..13116
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_149"
                     /sec_met_domain="ATP-grasp (E-value: 2.5e-07, bitscore:
                     24.7, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNIYWIGPRQSDIDNTNFKFAGSITIYGSNINGNTAYCSIANKR
                     INHNVDNDDCNRFFSEKLKEICHNDPKSQFLFYNFSYAYEFDDEIQKHVIGLNPYNIID
                     MLADKIRCRTILNNIVETVPFITLKGSECSFSNLCKYFCGYTEFVIQKKHSSGGEGTYI
                     INSNSDVIKLNAFDEYMISPYIKDSISLNVHIAIINNKTIVFPPSIQIITEQDGRLLYH
                     GADFICYQQISEKIKNEIKNLSTKIGDFVCKRGYKGVLGIDFLLNNGTIYFMEINPRFQ
                     ASSQLVNRGLLESNQSSLFEIHLQSFDLFPIRAISDFDVLYSNYVFSTNNITKTRLKKI
                     INSYEIEKFQADGYDIDCITPFEKNSYLCRCIFKQSICCININNKFTLHPNLFVEKIAY
                     NLFNKLNNKKEYIKFALLNHGVTLTKAALTYSRKQGTIREAVFDAIDITIFNNISVNVP
                     IKCKFVSFSPFTIDFIDNEYTLYWDDIRICTVSISFLPNNLINKKTLSGVPYDSIINLA
                     NDRIRINPAPICVYKLENESCQFCNLPTINDKYNINDIYEVIDYCLEYVDFRHFLIGGG
                     TYSKDGGWNIILNITKYIRSKCNKDIYLMSIPPKELSILDKLKDAGITEVAFNLEMFDR
                     NLAQNIMPGKGCIGLNQYLLAFRHSIKLWGNTGCVRSLLIYGFDTDDTFLSGIEQLCQL
                     GVEPIISIFRPLENTELSYLNPPPTSDILKIYQKCQDIVQKHNLILGPDCPQCQNNTLS
                     YTKIF"
     PFAM_domain     11158..11688
                     /aSDomain="ATP-grasp_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02655.16"
                     /description="ATP-grasp domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_149_0018"
                     /evalue="1.20E-10"
                     /label="ctg12_149"
                     /locus_tag="ctg12_149"
                     /protein_end="283"
                     /protein_start="106"
                     /score="41.8"
                     /tool="antismash"
                     /translation="ADKIRCRTILNNIVETVPFITLKGSECSFSNLCKYFCGYTEFVIQ
                     KKHSSGGEGTYIINSNSDVIKLNAFDEYMISPYIKDSISLNVHIAIINNKTIVFPPSIQ
                     IITEQDGRLLYHGADFICYQQISEKIKNEIKNLSTKIGDFVCKRGYKGVLGIDFLLNNG
                     TIYFMEINPRFQAS"
     CDS             complement(13121..14635)
                     /locus_tag="ctg12_150"
                     /transl_table=11
                     /translation="MKKLYSEKEIKESCIKVKRLLPDSDAMDNNFSLQYFNAEISKDFT
                     RKDLKRIAVNKSKFIKSKFNGAAATGSKFTKTKFAKCDFSGANFQYCYFINVSFTNDCL
                     IKGANFSHSVFIDCIFETTTIIESTLFDCLFENCTFISSEIRTDTLENSTMRNCKIRNI
                     DLSHINLEYMKFEKMQMENVTLPPYQIPYIIGATSYLNTTQDNVEIHTDNQNISKKEYC
                     SMYNDLAAFFYSHKEYFPLANIYIALNKDDLAYECIILGIQEACDLCDFRMVKHFCKLA
                     CSNENFSHPQLKSLYDIVTDLSHNNDWDLNVLHSYLLNIGEIRELLLNNLSHAQKVELL
                     IKTNINKDDLDAVNILYKQINNILRDNCSDKHIDSIELRHNSPYEFYITCVDSLPNIML
                     FISSIYTIFAAGNKFMDFYKKIEETRRVHQQNKLFKYELEEKKLDIKIKEKQIEQMDKQ
                     PSTQKKSGIYMVNEIEHSIKCSNLEVAQSIAPEYLHYKYSNNIQEQ"
     PFAM_domain     complement(14081..14311)
                     /aSDomain="Pentapeptide_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13599.8"
                     /description="Pentapeptide repeats (9 copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_150_0020"
                     /evalue="9.30E-08"
                     /label="ctg12_150"
                     /locus_tag="ctg12_150"
                     /protein_end="185"
                     /protein_start="108"
                     /score="32.3"
                     /tool="antismash"
                     /translation="NFSHSVFIDCIFETTTIIESTLFDCLFENCTFISSEIRTDTLENS
                     TMRNCKIRNIDLSHINLEYMKFEKMQMENVTL"
     PFAM_domain     complement(14333..14449)
                     /aSDomain="Pentapeptide"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00805.24"
                     /description="Pentapeptide repeats (8 copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_150_0019"
                     /evalue="5.00E-06"
                     /label="ctg12_150"
                     /locus_tag="ctg12_150"
                     /protein_end="101"
                     /protein_start="62"
                     /score="26.1"
                     /tool="antismash"
                     /translation="KFNGAAATGSKFTKTKFAKCDFSGANFQYCYFINVSFTN"
     CDS             complement(14719..15639)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 194.5; E-value: 5.4e-59)"
                     /gene_kind="other"
                     /locus_tag="ctg12_151"
                     /transl_table=11
                     /translation="MNNLQTHIEEYLKYCEIQKRLDAKTLKAYKIDLTQFMKEINTENF
                     IDITPSMLENFIANLHRKYKPKTVKRKIASIKALFHYFEYRDLIEKNPFNKLQIKFREA
                     ITLPKIIPLNYIEAILSTIYDSKVSAKTKFQQRNALRDVAVIELLFATGMRISELCSLG
                     INDINLDNGTILIFGKGSKERMLQIGNAEVINILKEYHADFLHECENCGYFFANQSGNP
                     LSDQTVRRMINKYTELASINLHITPHMFRHTFATSLLDADVDIRYIQEMLGHSSINITE
                     IYTHVATAKQKDILSTKHPRNMFNV"
     PFAM_domain     complement(14779..15243)
                     /aSDomain="Phage_integrase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00589.24"
                     /description="Phage integrase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_151_0022"
                     /evalue="1.10E-45"
                     /label="ctg12_151"
                     /locus_tag="ctg12_151"
                     /protein_end="287"
                     /protein_start="132"
                     /score="155.6"
                     /tool="antismash"
                     /translation="KFQQRNALRDVAVIELLFATGMRISELCSLGINDINLDNGTILIF
                     GKGSKERMLQIGNAEVINILKEYHADFLHECENCGYFFANQSGNPLSDQTVRRMINKYT
                     ELASINLHITPHMFRHTFATSLLDADVDIRYIQEMLGHSSINITEIYTHVA"
     PFAM_domain     complement(15394..15618)
                     /aSDomain="Phage_int_SAM_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02899.19"
                     /description="Phage integrase, N-terminal SAM-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_151_0021"
                     /evalue="2.40E-11"
                     /label="ctg12_151"
                     /locus_tag="ctg12_151"
                     /protein_end="82"
                     /protein_start="7"
                     /score="43.8"
                     /tool="antismash"
                     /translation="IEEYLKYCEIQKRLDAKTLKAYKIDLTQFMKEINTENFIDITPSM
                     LENFIANLHRKYKPKTVKRKIASIKALFHY"
     CDS             15905..16201
                     /locus_tag="ctg12_152"
                     /transl_table=11
                     /translation="MIYNVKESGRRIKELRKQKGYTQESFADDIGISVRTYSGIESGAH
                     STSIDTFVEIAEKLNVSLDYVILGQRENNLSIKVKKEEREIIKKFLYNIIQGV"
     PFAM_domain     15938..16102
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_152_0023"
                     /evalue="4.20E-18"
                     /label="ctg12_152"
                     /locus_tag="ctg12_152"
                     /protein_end="66"
                     /protein_start="11"
                     /score="65.2"
                     /tool="antismash"
                     /translation="IKELRKQKGYTQESFADDIGISVRTYSGIESGAHSTSIDTFVEIA
                     EKLNVSLDYV"
     CDS             16211..16351
                     /locus_tag="ctg12_153"
                     /transl_table=11
                     /translation="MIRSKYVSNHIKSKKKIKYSYIVIKKRAHLLVEILMKEGNIYVKD
                     F"
     CDS             16335..16703
                     /locus_tag="ctg12_154"
                     /transl_table=11
                     /translation="MLKIFNRKEAVNGVIFIKSIKDLNTVINVAKDIGKECKRRGLNVE
                     YCFLDTSEDNVIERKAIKQFLDEMQDKNINLVVLRTLDDISNNPIEREAFLTVMNDNGV
                     GIYLFEEGCFAMVNYNFE"
     CDS             16762..17106
                     /locus_tag="ctg12_155"
                     /transl_table=11
                     /translation="MYGGGNILKYEGWNVGSTIRRLRKEKNMTIEELSEAVGKSPSHIA
                     QIEQGSRRLGINLLYELITVLETDANTILVVHRKNSDLSIDKELMKLTPKVRIYFQKQF
                     LNMIEEFPIK"
     PFAM_domain     16816..16968
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_155_0024"
                     /evalue="4.40E-12"
                     /label="ctg12_155"
                     /locus_tag="ctg12_155"
                     /protein_end="69"
                     /protein_start="18"
                     /score="46.0"
                     /tool="antismash"
                     /translation="IRRLRKEKNMTIEELSEAVGKSPSHIAQIEQGSRRLGINLLYELI
                     TVLETD"
     CDS             17121..17489
                     /locus_tag="ctg12_156"
                     /transl_table=11
                     /translation="MGKKNRTIKVIAYLSVVNATEKNVEWKEDKQLRYIREYAKAHCIR
                     IVKILRRNILGKNVRDAQFRKMIGAIECGMVDGIIVCKMALISDTVVDAYKKVGDVVQA
                     GGHMITVDEGELNLPLKM"
     PFAM_domain     17199..17462
                     /aSDomain="Resolvase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00239.23"
                     /description="Resolvase, N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_156_0025"
                     /evalue="2.00E-05"
                     /label="ctg12_156"
                     /locus_tag="ctg12_156"
                     /protein_end="114"
                     /protein_start="26"
                     /score="24.8"
                     /tool="antismash"
                     /translation="KEDKQLRYIREYAKAHCIRIVKILRRNILGKNVRDAQFRKMIGAI
                     ECGMVDGIIVCKMALISDTVVDAYKKVGDVVQAGGHMITVDEG"
     CDS             17505..17867
                     /locus_tag="ctg12_157"
                     /transl_table=11
                     /translation="MRQIMRGDVIYVDLGQHPNSSIQSGIRPCVVISNNQNNKYSKVIS
                     VCPCTGRVTKKKVITHILVTTKDVNGYFQKNSILLIEQITVVEKKQIISKVGHIPRDSE
                     VMKKVNCLIKKQLGVD"
     PFAM_domain     17520..17852
                     /aSDomain="PemK_toxin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02452.19"
                     /description="PemK-like, MazF-like toxin of type II
                     toxin-antitoxin system"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_157_0026"
                     /evalue="8.40E-22"
                     /label="ctg12_157"
                     /locus_tag="ctg12_157"
                     /protein_end="116"
                     /protein_start="5"
                     /score="77.7"
                     /tool="antismash"
                     /translation="RGDVIYVDLGQHPNSSIQSGIRPCVVISNNQNNKYSKVISVCPCT
                     GRVTKKKVITHILVTTKDVNGYFQKNSILLIEQITVVEKKQIISKVGHIPRDSEVMKKV
                     NCLIKKQ"
     CDS             17919..18116
                     /locus_tag="ctg12_158"
                     /transl_table=11
                     /translation="VNENTNVIEPALLTLEQACKYLCIGKTSCRKLFKEHEHEFVVRIG
                     NRLYANKSLLDKWIDDQTRA"
     PFAM_domain     17952..18101
                     /aSDomain="HTH_17"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12728.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_158_0027"
                     /evalue="2.70E-06"
                     /label="ctg12_158"
                     /locus_tag="ctg12_158"
                     /protein_end="61"
                     /protein_start="11"
                     /score="27.6"
                     /tool="antismash"
                     /translation="LLTLEQACKYLCIGKTSCRKLFKEHEHEFVVRIGNRLYANKSLLD
                     KWIDD"
     CDS             18270..19484
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 140.1; E-value: 2e-42)"
                     /gene_kind="other"
                     /locus_tag="ctg12_159"
                     /transl_table=11
                     /translation="MGKKTLVKTKKEPNIRRRSNGLWEARKQINGIPIRVTGHDKKQVL
                     AEFDKKVEEAENPALISSDITVDAFRDKWFNTFKVPKIKTTSIYPMTRRYERTFGNRIG
                     KRKLNSLTCFDIQVAINGMLSDGIGITTIKDALGSFRECLESAKNNGLIAINPCFEIIL
                     PEKTNSKQRRFLTVDEQKRFLETAETEYGWYYPMLKVMLLTGMRISEVGGLCWSDIDYD
                     NDVIHIRRALFSQYEYGKKKLHFTTTKTINSVRDIPMMADCKKMLRLQKKNQNKIKKEL
                     GKRYRSENEEGLSDLVFTSSMGSAATRYNVAPIINKIVKSINLREDYESVKENRKPIYM
                     EPVSPHALRRTFCTRCFEAGMNIKVVQKIMGHSNYAVTANIYTEVMPDKMNEEVELFNS
                     KLLTM"
     PFAM_domain     18789..19424
                     /aSDomain="Phage_integrase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00589.24"
                     /description="Phage integrase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_159_0028"
                     /evalue="1.60E-29"
                     /label="ctg12_159"
                     /locus_tag="ctg12_159"
                     /protein_end="385"
                     /protein_start="173"
                     /score="103.0"
                     /tool="antismash"
                     /translation="FLTVDEQKRFLETAETEYGWYYPMLKVMLLTGMRISEVGGLCWSD
                     IDYDNDVIHIRRALFSQYEYGKKKLHFTTTKTINSVRDIPMMADCKKMLRLQKKNQNKI
                     KKELGKRYRSENEEGLSDLVFTSSMGSAATRYNVAPIINKIVKSINLREDYESVKENRK
                     PIYMEPVSPHALRRTFCTRCFEAGMNIKVVQKIMGHSNYAVTANIYTEV"
     CDS             20020..20247
                     /locus_tag="ctg12_160"
                     /transl_table=11
                     /translation="MSVSYNGLWKLLIDKNMKKIDLTNNLGISSSTVAKMTKGEKVSMN
                     ILEKICDELDCDFGDLIHYEKNKDGGKDEL"
     PFAM_domain     20041..20217
                     /aSDomain="HTH_26"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13443.8"
                     /description="Cro/C1-type HTH DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_160_0029"
                     /evalue="7.60E-18"
                     /label="ctg12_160"
                     /locus_tag="ctg12_160"
                     /protein_end="66"
                     /protein_start="7"
                     /score="64.8"
                     /tool="antismash"
                     /translation="LWKLLIDKNMKKIDLTNNLGISSSTVAKMTKGEKVSMNILEKICD
                     ELDCDFGDLIHYEK"
ORIGIN
        1 ggatctacag ataaaactcc agagatatgt cataagtatg aaaaaaaata tgaaaatata
       61 agagtagtac ataaagaaaa cgaaggggta tctgctgcaa gaaatagagg aattgaggag
      121 gcaactggtg attatatact gtttgttgat ggggatgatt ggatagaaaa taatacaatt
      181 gaagcattgg tttggttgga agaagagaat gaatcggata tcgcttttat cattaaagca
      241 ggaaatgagc attcaacagg agaggtactg attggtgatg gaaagaaaat gatattacat
      301 attttggaaa tatcggctgg tgaagtttgg gggaaattat ttaaaaaaca aatatttgaa
      361 gacgtgaagt ttccggaagg gaagcttcat gaggacttat atgtgatgcc aactattttt
      421 ttaaaatgta aaaagatagt tgcatatcac aagggattat atcattacag gattagagat
      481 gatggattga tggggacaga aataaaagga aatttgaaag atttatatga atgctggtta
      541 gatggaataa gaaaatgccg tttgttaagc tctgataaaa aatttgtgaa agacttgcaa
      601 aaaaggtatc tgtatgatgt gttatggtat ttttacaata tagtatgtct tatgagtgat
      661 gaaaaattta aagagtccgt agtaaatatt tcattgtttt ataaaaaaac gagatatata
      721 tatttaataa attcggcagt gaaaattagt gatagaataa gattcctttt gatatcaata
      781 tgtccaatga ctgtcaggaa ctttaatata ctacgatatg gtcgtggata aaaataagag
      841 gagtgaatat gaacaaaaga gttacgcaag cagtcattct tgctggtggt ttgggtacac
      901 gtctaaaacc atttacaaat actaatccta aaccgatgta tccgattaat aacgttccat
      961 ttattgatta tctaatacgt cagatgaaga atttcggaat ggaagaggtg ctactccttt
     1021 taggatatct acctgaaaaa ataatggatt atcttggaga tggttcacgt tatggcttaa
     1081 ctataaatta taatattaca cccgtggatt acgacacagg tatgcgaata aaacatgctg
     1141 ctccacagat tgcagataca ttttttcttt tatattgtga taattattgt ccaattaact
     1201 atttaaaatt gttctcagac ttttgtaata ataaagcaaa gattcaaatt acagtctata
     1261 gcaatcgtga caactatacc aaaaataatt tacatattac tgacgatggt ttggttacaa
     1321 cttatgataa aaaacgtatt agatcaaatt tacagggggt tgatatcggt tatgccttag
     1381 ttgataaaag tgttatttct ctgctaccag aggaaaattg taattttgag tcagaaattt
     1441 atactcaatt agttcaaaag aaagaaatat ttgcaacagt gacagaacat agatattatt
     1501 ctgttggttc ttttgaacga atcaaactta caagagaatt tttcaaacca aaacgtgttg
     1561 tatttcttga tagagatggg acgataaata aacgcccaaa acaagcttgc tatgtagaaa
     1621 aaccagaaga ttttatttgg cttccgggag cattagaagc aatccgtttg cttaaaaata
     1681 atggattcct tgtaattgta attactaatc aaccaggaat tgcacgaggt aatcttacag
     1741 aagaaatgtt atattgcatt catgcgaaaa tgcatatgga gcttttaaag gcagaaacag
     1801 aaattgatga tatactttac tgccctcata attggaacga gggatgcttt tgcagaaagc
     1861 caagtccagg tatgctttat gaagcacaga aaaagtacga attaaatctt tctgaatgtt
     1921 atcttatagg agatgacgaa agagacattg aagcaggaac aattgcagga tgtaagtgta
     1981 gaatggttga tgaaaaacac acgatattgg acgtcgtgaa agagatagtt gcattagaga
     2041 aaaaaggaga agatacatga ttatttcaaa aacaccccta agagcttcat tttttggtgg
     2101 tggaacagat ttttccactt actatgaaaa cagtaagtta ggttatggta cagttgttag
     2161 tacagctttg gatatgtatg tttatattac tgtaaataag aagtttgatg atagcattag
     2221 aattgtgtat tctgataatg aattagttag taatgtggat gaagttaagc ataatattat
     2281 tagagaagca ttaaaaattg tcggaataga aagaggaatt gaaattgttt atatggcaga
     2341 catacctttg agcaatgcgg gaattggact tgcttcatca agtgcattag cggttggagt
     2401 gttgaatgca ttacatgtct ataaaggtga gtttgtatcg caaggtgttt tagcacgtga
     2461 agcatgtgaa atagaaatta atcgtttagg tcaacgaatt ggaattcaag atcagtttgc
     2521 tgttgcacat ggtggcttta atcaatacaa attttttagt aatggaagtg taagtgtttc
     2581 accaatagtt tgcagaaaag atatagtaga aaacttaaaa aagaatttaa tgctatttta
     2641 tacaggaaat actagggatt caagagaaat tcttaatgaa caatcggaca caatagtaga
     2701 aaaaacagta atgctagatg atttagtgaa cacaacagat tgtgcagtaa gggctttata
     2761 tgatggaaat atagactact ggggaactga acttgaccga acatggaata ttaagaaaaa
     2821 atttgctaaa ggtatatcaa atttattaat agatgaaatg tataataagg ctaaaagtgc
     2881 cggtgctatt ggtggaaaaa ttcttggtgc aggtggtgga gggtttatgt tactttatgt
     2941 tccacaaaaa aaacaagatt cagtaaaaaa agaacttgca gattttagaa atattccgtt
     3001 ttcttgcagt aatgaaggca gtaagattgt cttttacgat taatggagga aaggattatg
     3061 gattatagaa aattaattaa gagttatatt gaaaatgaaa tagaaaccat aaataaaatt
     3121 gacatggacc aaataaatgc agctttaaat ttattggaag caggaataaa aagagaagca
     3181 acagtctatg tatttgggaa tggtggtagt gcagcaacag catcacatat tcaaaatgat
     3241 tttaataagg gaatatctga acacacaaag gagaaattta gatttctctg tctaaatgat
     3301 aatatagcta cagttatggc aatagcaaat gatataggat atgaagaaat atttcgcttc
     3361 cagctaattg gaaaaataaa aagtaacgat attatagttg ccatatctgg aagtggaaac
     3421 tcaaaaaatg taattaacgc agtagagtat ggtaaaaatc atggttgtaa agtaattggt
     3481 atgacaggat attcaggagg aaaattaaaa gagttggcgg atatttcttt acattcacct
     3541 atcaatagta tgcaaattac cgaagatata catatgattt ttaatcattt gatgatgagt
     3601 attttttaca agactatgtg cggaattaat catattaaaa ataaaggaga tactgatgag
     3661 caaaatattt attagtggtg cggcaggatt cataggttca caactttcgt attatttatt
     3721 caaaaaagga tatcatgtaa cattacttga taatttttca tatggagtgg aagataattt
     3781 gatttttcct gattgtgatt ttaggggaaa aataattaga ggggacataa gagacaaaaa
     3841 tctcattgat gagttattta aaaaaaataa atttgattat gtttatcaca tagcagctat
     3901 tacaccactt ccagattgtc agataaaccc gatagaagct gtagatgtaa acataacagg
     3961 aactttaacc atacttgagg caagtcgaac atacggagta aagaagttag tgtttgcaag
     4021 tacttcagca gtatatgaaa ataatgaaaa attcccatta ttcgaggaaa atccagtacg
     4081 accaaactta atttatccat caactaaata tgcagcagaa caattttgtt atgattatgt
     4141 aaaaaattat gatatgaata ttacatgttt aagatttgca aatgtatatg gaccacatat
     4201 agattgtttg cgtaagcaac ctccagttgt gggatatatt ataagagaac ttttttatga
     4261 tagaagtcct attttacata gtacgggcaa tcagagcagg gattttgtgt atgtagaaga
     4321 tttaataagt ctttgtgaaa tggttttgaa tggaaaagga tttgatattg ttaatgtttc
     4381 tagtggaata tctgtatcaa ttaatgaatt aatgcttatg atttcaaaac tgatgaatag
     4441 agaggaaatc aatgcgattt ataaaggaga agcttttttt tggaaaaagt atcctgaatt
     4501 atataaaaag ccatatccca taaaaaatga agtgttagta catgaagtga aaaaatatac
     4561 taacctttca aataaacatg catttgaaag gtatggatgg aaaccgcaaa cttcaatgga
     4621 agaaggttta aaaagaacaa taagttttgt atgtgaaatg ttagagaagc attgttaaaa
     4681 ataaaatatg ttactaacag tattatatat aaatgtaaat ggaggaaaat acaatggaga
     4741 aaagattatt tacatctgaa tcggtaacag agggacatcc agataaaata tgtgatcaga
     4801 tagcagatgc aatattagat gaatatatga aaaaagatgt caatagcaaa gtggcatgtg
     4861 aagttgcaat aacaacagat tttgtcttga ttatgggaga aatcacgtct aatgcaaaag
     4921 taaatattga taaaattgta agagacacaa tcagagatat tggatatgat aatgtagagt
     4981 atggatttga ttgtgataat tgtaacgtga ttattaacat agatgaacaa tcaacagata
     5041 ttgctttagg agtagataaa tataaattag ataaagtaaa taaatcgtca gatttgatag
     5101 gtgcaggtga tcaggggatg atgtttggat atgcaacgga cgaaacaagt gaaatgatgc
     5161 catatcctat ttatttggct cataagttaa caaaaaggct taccgaggta agaaagaatg
     5221 gaatacttaa atacttaaga ccagatggaa aaagtcaagt tacagtagaa tatgattcag
     5281 atgataagcc agtaagaatt gaagcagttg taataagtac acagcataat tcggaaattt
     5341 cacaagaaca attgcacaaa gacataagaa aatatgtaat agatagtacc atacccccta
     5401 atatggttga ttctaaaact aagtattata tcaatccgac aggaaggttt gtaataggag
     5461 gaccacatgg tgatagtgga cttacagggc gaaaaattat tgtagacaca tatggaggat
     5521 atgctcgtca tggtggtggt gctttttcgg gaaaggattg tacaaaagtg gatcgctcgg
     5581 cagcttatat ggcaaggtat gtagcaaaaa atattgttgc tgcaagactt gctgaaaaat
     5641 gcgaaataca gttatcatat gctataggag taacagaacc aatttctatt tcagtgaata
     5701 catttggaac aggaaaggtc agcgatagca aattaataca aatcatacga aacaaatttg
     5761 atctatcgcc atatggaatt ataaaatttt ttgacttaag gagacctatt tatagacagg
     5821 tagcagctta tggacatttt ggtcgaaatg agttggaact tccatgggaa aaaacagata
     5881 aagtatctga aattataaaa gaactttagt taagtgaaaa atacataata tagaactaaa
     5941 ggtaagataa gattgaacta tagctggttt agtaaagtaa cagttgagtt tatagtaata
     6001 gtaacacaaa agatagggga gaagcgttac tatggaaaag gaaacgaatg ctggtacaag
     6061 agtaagatat gccagagaat taaatcattt cacgcgtgag gaacttgcag agtatgctgg
     6121 gatatcaaca aagtttttgt atgaaataga aaataaccat aaaggtatgt ctgcacatac
     6181 attattaaat atctgtaaag cattagatgt ttcttgtgat tatattatga caggtggagg
     6241 tgattacact tgtgatcagg aagtaattac aattatagaa tcttttgatg catcacaaat
     6301 tccaaatgta aaaaaaattc ttacagaatt attagaacta agcaaatact aataatatat
     6361 ggtttttcaa cctcctctaa gctgcctgaa aaggcagctt tttttgaaag caaattagaa
     6421 tactaaaata ttggaaaaga tggttttaaa aatgttattt aattacagat aaaagtaatg
     6481 ttttttgtga taaatcatat aaatgattaa tttaacacat aataaattcg tgttcgttaa
     6541 aatatatgtt gcattggtga tactgtgtat aataatagat agtagaataa ggggataaga
     6601 tatgaattat atgcactcaa gtgaaaaaat aaaaggcctc agaatacacc aaggttatac
     6661 ggttgaacaa ttggcggaag aggcaaatat ttcaactaaa ttcttatatg aaattgaagc
     6721 aggtaggaaa gggttttcgg caaatgtgtt atataaaatt tctaaagcac taaacgttag
     6781 ttgtgattac atattaaatg acagtaatca acaaacagtt cctgatttta ttatcgaatt
     6841 agtgaaaaaa ttagatagta aggaacaggt cgcagtggag cacattttgg tggaaataat
     6901 cagactgaga gaagaataag tttaatacct ggagataaat ataatgaaat acgattattt
     6961 agattatgag caaattaaaa aaatgggaga gaggataaaa ataagtagaa aaagcaataa
     7021 tatgacacaa agcgaattgg ctgatatttt gggaatatca gcagatcagg tctcaaatat
     7081 tgaattagga aaaagtgcct gtaaaataga tcacatatac ttgttgatgc aagtattgga
     7141 tatatcggct gattatttgt ttggaaattt tgtaaataca aatgtagtgc gggtaactga
     7201 tgagcaaata ataaatatgg caacgaaaac aaataaaaag atgaaaatga taatatatga
     7261 gttacttatg cttatggcat agtactcata tattttttta taagtggcat aaatatacta
     7321 tgaacgcata tgacataaag tagcgtgtga cgtgctacat tgtgcaatgg tgcatacaca
     7381 aaaaagaatt taaaatcatt tagtgaaaaa agcgggagtg gtatagttat atggacaaga
     7441 aaatgatatc gagaaaagac aggcagaaag caaaaagatt aaaaagtgta agagataggc
     7501 aacatttaac acaggagaaa atggcggaaa gattagatat atcgtattca acatatcaaa
     7561 gaatggaaag tggacgaaac aatattacta tcgaacattt ggaaaagttg cataaagagt
     7621 ttggagtatc atcggattat attttatttg gtacagtcaa cgacgaaaaa cattatgaac
     7681 tggaactcga atatatgaat gataaaacaa aatttttaat ggttactagg ctgatagcgt
     7741 gtttatgcag attggatgaa aataaataca aagaacttat gataaaatta gagaaagatt
     7801 taaaagaaat acaataggtg gcaggtaatg cgtatgaata cttcagataa acaaatttta
     7861 atagtagaag ataataataa aaatatggag aagctatgcg aggtactgaa agatattaaa
     7921 gatgtctata tacataaggc aaagaatagt gaacaggcat atagatatgc attggagtat
     7981 aatatagacc tatttattgt agatattata ttgaatacca aagtgtttgc tgatatatca
     8041 gggctaaaat tcatagaaag cattcgatca attaatggtt ataaattcac accaattata
     8101 gtaacaacgt ctttagaaga tcctaaattt catgcttatt ctaatctaca ttgtttcaga
     8161 tattatgaaa agccttatga ttatgcagaa tttaagaaat cagtagttga ggcattagaa
     8221 tatacaacac ccaaaaaagc taaagatttt tattattaca aagatgatgg agtcatttat
     8281 tctatcaaaa caaaaaatat tgtatatttt caaacaaata atagaattac ttacataaaa
     8341 tgcaagaatg gaaaggtaat gccaacacct tataaatcta acaaaaagat attattagag
     8401 ctgaattcaa aaaagtttct cagatgtagt aataatacaa tagtgaacgc tgagtatata
     8461 gaagggatag ataagtcaaa tagatatgtt atgttggtag atggttttgg aacattggaa
     8521 ataggaccca agttgaagaa aaaattttta gaggactttt tcaaatgtta gaaagaatat
     8581 attggttatt agaaattatt tccttggcaa tatgtataag tagtatttat ggtgtgaaaa
     8641 ttaaggcaga tattaaaaca gtagcttgga ttgctataga agttatgttt atgggaatgt
     8701 ttaaaagaaa tttaattaca atgcaaacat attttatcat atatgtgttg tatattttgt
     8761 atgtatatat tgaatttaga atgtctttaa aaatagcaac ttttacagca atattaagta
     8821 tgatatttac aggattgatt cagatgataa ttgcacttcc ggtgtattac ataggagatt
     8881 actgtaaaac aagcgaaaac ataatggtct tagtaattaa tgctggtgtt ttaatggctg
     8941 ttgtactcat aagtaaaaca aaatttctac acggtgttta caaattttta gcaagaaaag
     9001 agttgatttt gaatataacg tttatactgg taatgttcat atatggatat tgcatgtata
     9061 gaataaagta tagtaacaaa atacaatctg acttgtatgt aattattgta acgtttgcat
     9121 caataatagc ttgtatttta ttaagatgga aagtaatgga aagggagaca gaatatcaac
     9181 aggagcagat aaaattgtca aatcgttata gtgaagagta caatgcttta gttgaaatat
     9241 caagaaaaaa gcaacatgat ttcaaaaatc agattaatgc attatatggt ttgtcagata
     9301 taaaagcaga aaaggaacaa agaaaatata tagacaaatt gttagacgaa aataaagttg
     9361 tcaaaatatt gcattctgta gaacagcctg tattagctgg attcttatat cgaaaagtga
     9421 atgagattat ggcagcagga ataaatatag aatttaattt atctgttcca gacgcagagt
     9481 tagcgataga agtgtttgac tgtattgaaa tagtaggaat acttttggat aatgcagtgg
     9541 aagcattgaa taaagaaaaa gataaaagta ttattctaga aatgttcaca atggaacaaa
     9601 aggttgaaat aagggttaaa aatgtaagcc cttattatga gaatgatgag atttcaaagt
     9661 tctttcagta taattattct acaaaaggca aaaatagagg aataggttta gctaagataa
     9721 aagatttaca gaaaaagtat aaatttgata ttttagttga aatgcaggaa atacataata
     9781 aaaactggat aagtttttca gtaattaaat aaagaatagt aaaagccccc ctaaagttac
     9841 cattttgata actttagggg gtttttagca ttagtgttct attggcgttg ggaattttct
     9901 ttcaccaaaa agtagaaaac taattccaga aaaatgaata aatgacatta aagccagaca
     9961 tgaaccacaa attttgttca tgcatgataa acttaatttt ttacgaaaca ttttttagac
    10021 ctcctttgat tattagaatt ttagcaaaca tcatttgaca tgtgtgtaat atgatagtcc
    10081 aaaagccaat aattaaatat ggatatatta tgctatggct attgaaaatg ctaactatta
    10141 taaaaaaagc aaatataata agaaaactat tgttctgaca gtgttttaac aatacgctat
    10201 ttggagatgg tctaagaggt gaaactattg gaccaatgta atagttaatt aggatacaga
    10261 caatagtaaa aaattgaata aataagatat ccggagttat taattgtgga aggataacta
    10321 ctgccagata agatatcacg aaagttaaca gcaaacaggt tgtataatgt ttacaatgaa
    10381 agccaccact gttaaatcta attaatgata ataaaagtat aaatacggta aaacttaaaa
    10441 ctttaccaat aataatgtaa aaaatatata gcaatagtat cttgctaaat tcagatgcaa
    10501 tggaaagtaa tgtatacttt actaattcca attcataatc tgaatagtta tatgttgttt
    10561 ttaaggcttg tctgatttta tccatagtaa atagtccttt gtaagttgtt gactatatca
    10621 tatatggtgt agcggataat attagatttt tttcagaaag ttgatttttt tacaaaaaaa
    10681 gaagaaatat atatgcttat agaaaaagaa agatcttttt agaagaaaaa acgtagaaaa
    10741 tgaaaaataa gaaaaggttg ggtgaaattg ggtgagggat gtagtataat aacagataat
    10801 tgatgattat tcatcatttt tttacaatgg aggtagaata tgaacaatat atattggata
    10861 ggtccacgtc aatctgatat tgataataca aattttaaat ttgcaggatc aataacaatt
    10921 tatggaagca atattaatgg caatacagca tattgctcca tagctaataa aagaataaat
    10981 cataatgtgg ataatgatga ttgtaatcga ttttttagcg agaaattaaa agaaatatgt
    11041 cataatgatc ctaagtccca atttcttttt tacaattttt catatgctta tgaattcgat
    11101 gatgaaattc aaaaacatgt gataggatta aatccatata acataatcga tatgttagct
    11161 gataaaataa gatgcagaac aattcttaat aatatagtag aaacagttcc atttattaca
    11221 ttgaaaggtt ccgaatgttc atttagtaac ttatgcaaat atttttgtgg ttatactgaa
    11281 tttgttattc aaaaaaagca ttcttctggt ggagaaggga catatatcat caattcaaat
    11341 tctgacgtta ttaaattaaa cgcttttgat gaatatatga tttcccctta tataaaagat
    11401 tcaatatcat taaatgttca cattgcaata ataaataata aaacaattgt gtttccaccg
    11461 tctattcaaa ttattacaga acaggacgga cgcttattgt atcatggtgc agattttata
    11521 tgctaccaac aaatatctga aaaaataaaa aatgaaataa aaaacttatc tactaaaatt
    11581 ggtgattttg tatgtaaacg tggatataaa ggtgtattgg gtatagattt tctattaaat
    11641 aatggaacaa tttattttat ggaaatcaat cctcgttttc aagcttctag tcaattagta
    11701 aacagaggat tgttagagtc taatcaaagt tcgctttttg aaattcattt gcaatctttt
    11761 gatttgttcc ctatcagagc gataagtgac tttgatgttc tgtatagtaa ttatgtattc
    11821 tcaaccaata atattactaa aacaagacta aaaaaaataa ttaattccta cgaaattgaa
    11881 aaatttcaag ctgatggata tgatatagat tgtataacac catttgagaa aaattcttat
    11941 ttatgtagat gtatatttaa acaaagtatc tgctgtataa atataaacaa caaatttact
    12001 ttacatccaa atttatttgt tgaaaaaata gcatataatt tatttaacaa attaaataat
    12061 aaaaaagagt acataaaatt tgcactatta aatcatggag taactcttac taaagctgca
    12121 ttaacatatt cacgaaaaca aggaacaata agagaagcgg tatttgatgc gattgacatt
    12181 acaatattta ataacatttc agtgaatgtc cctataaaat gtaagtttgt ttcatttagt
    12241 ccttttacaa ttgattttat tgataacgaa tatactcttt attgggacga tattagaatt
    12301 tgtactgttt ccatttcatt tttgcctaac aacttgatta ataaaaaaac tctctcagga
    12361 gtcccatatg attcaatcat aaatcttgca aatgatagaa tacgtataaa cccagctcct
    12421 atttgtgttt ataaattaga aaatgaatca tgtcagtttt gtaatttacc aacaataaat
    12481 gataaatata atattaatga tatttatgag gttattgatt attgtttgga atatgtggat
    12541 ttccgacact ttctaattgg aggtggtaca tattcaaaag atggtggttg gaatataata
    12601 ttaaatataa ctaaatatat tcgttctaaa tgtaacaaag atatatatct tatgtcgatt
    12661 ccacctaaag aactatcaat attagataaa ctaaaagatg ctggaattac cgaggttgca
    12721 tttaatttag aaatgttcga ccgtaatcta gcacaaaata ttatgccagg gaaaggatgc
    12781 ataggattaa atcaatatct attggctttt agacattcaa taaagttatg gggaaatact
    12841 ggctgtgtac gaagcttgtt aatttatgga tttgacacag acgatacttt tttgtctgga
    12901 attgaacagc tttgtcaatt aggggtagaa ccaataatat caattttcag acctttggaa
    12961 aatactgaat tatcatattt gaatccaccc ccaacgtctg atattttgaa gatatatcaa
    13021 aaatgtcaag atatagttca aaaacataac ttaattttgg ggcctgactg tccacaatgt
    13081 caaaataata cattgagtta cactaaaata ttttaaaata ttattgttcc tgaatattgt
    13141 tgctatattt ataatgcaga tattcaggag caatactttg agcaacttct aaattactac
    13201 atttaatact atgctcaatt tcatttacca tatatattcc tgatttcttt tgagttgatg
    13261 gttgcttatc catttgttca atttgctttt cttttatttt tatgtctaat tttttttctt
    13321 ctaattcata tttaaaaagt ttgttttgct gatgaactct acgtgtttct tcaatttttt
    13381 tgtagaaatc cataaactta ttgcctgctg caaaaatggt atatattgaa ctaataaaca
    13441 acattatgtt tggtaatgaa tccacacatg taatgtaaaa ttcatatggt gaattatgtc
    13501 gtaattctat agaatctata tgtttatccg aacaattatc acgtagaata ttatttattt
    13561 gtttatacaa tatatttact gcatctaagt catctttatt tatattagtc ttaattaata
    13621 attcaacttt ctgtgcatga gacaaattgt taagtagcaa ttctctaatt tctccaatat
    13681 ttaataaata tgaatgtaat acgttcaaat cccaatcgtt attatgtgac aaatcggtaa
    13741 ctatatcata taatgatttc aattgaggat gagaaaagtt ctcattagag catgctaatt
    13801 tacaaaaatg ttttaccatt ctgaaatcac ataaatcaca agcctcttga atacctaata
    13861 taatacactc atatgctaaa tcatctttat tcaatgcaat ataaatattt gctaacggaa
    13921 aatattcctt atgtgaatag aaaaatgcag caaggtcgtt gtacatcgaa caatattctt
    13981 tctttgatat attttggtta tctgtatgta tttccacatt atcctgtgtt gtatttaaat
    14041 aactagtagc acctataata tacggaattt gatatggtgg aagtgtcaca ttttccattt
    14101 gcattttttc aaatttcata tattctaaat taatgtgtga taaatcaata tttcggattt
    14161 tacaattacg cattgtagaa ttttccagag tatccgttct gatttcagac gaaataaatg
    14221 tacaattttc aaataagcaa tcaaacaacg tgctttcaat tattgtagtt gtttcgaaga
    14281 tgcaatctat aaatacgcta tgactaaagt ttgctccctt aattaagcaa tcgttagtga
    14341 aggaaacatt gataaaataa caatattgaa agttagctcc actaaaatca catttagcaa
    14401 atttagtttt tgtaaatttt gatccagtag cagctgctcc attaaattta cttttaataa
    14461 acttagattt gttaactgct attcttttta aatcttttcg cgtaaaatcc ttagaaattt
    14521 ctgcattaaa gtactgtaat gaaaaattat tatccattgc atcactatct ggtaataatc
    14581 tttttacttt aatgcaggat tcttttattt ctttctctga atataatttt ttcataagtg
    14641 ttctccatta tgtaaacata gttttttgat gaataatcat caattatcaa tcaaaaaata
    14701 aaattattta tgatgaagtt agacattaaa catattccta gggtgtttag tacttaaaat
    14761 atctttttgt tttgcagtag caacatgagt gtatatttca gtaatgttta ttgaactgtg
    14821 tccaagcatt tcctgaatgt atctaatatc aacatctgca tctaaaagac ttgttgcaaa
    14881 tgtatggcgg aacatatgtg gtgttatgtg tagatttatg gaggcaagtt cagtatactt
    14941 gtttatcatt cttcgaacag tttggtctga gagtggattg ccagactgat tggcaaaaaa
    15001 atacccacag ttttcacatt cgtgcaaaaa atctgcgtga tattctttta aaatattaat
    15061 aacttcggca tttcctattt gtaacattcg ttctttagag ccttttccaa aaattaaaat
    15121 tgttccgtta tctaagttaa tgtcattaat accaagagag cacagttcag atattctcat
    15181 acctgtagca aataggagtt caatgacagc tacatcacgt aaggcatttc tttgctgaaa
    15241 tttagttttt gcagaaactt tggaatcata tatagtagat aaaattgctt cgatatagtt
    15301 caagggaatt attttaggta atgttattgc ttctctaaat ttaatctgaa gtttgttgaa
    15361 tggatttttc tcgattaaat cacgatattc gaaataatga aataaggctt tgatagatgc
    15421 aattttgcgc ttgacggttt taggtttata ttttctgtgt agattagcta taaaattctc
    15481 aagcatagaa ggtgtaatgt caataaaatt ttcagtatta atttctttca taaattgtgt
    15541 taaatctatt ttataagcct ttagtgtttt tgcatctagt cttttttgaa tttcacaata
    15601 ttttaaatat tcttcaatgt gtgtctgtaa attgttcata ataataaatc tcctttgtaa
    15661 attaaattta gtaatataca tcttatatct ttttattggt tgtttaaata ttaaaaagca
    15721 tgctgtattc aaaaataaaa tttaaataaa aaataaagtc tatatgcaat taagaaaata
    15781 aactttgttt tcccaatttg gttaggaaga aaatgtacga atattaatat agaatttatg
    15841 aagaacattt ttgtattaga taataaaaat ttatctggta taaatcagaa aagagagaaa
    15901 acatatgatt tacaacgtaa aagaaagcgg cagaaggatt aaagaactaa gaaaacagaa
    15961 gggatatacg caggaaagct ttgcagatga tataggtatt tcggtaagaa cttatagtgg
    16021 tattgaatcc ggggcacata gtacgagtat agatactttt gtagaaatag ctgaaaaact
    16081 aaatgtttcg ctagactatg tgattttagg acaaagggag aataatttat cgattaaggt
    16141 aaaaaaggaa gaacgagaaa taattaaaaa attcttatat aacataattc aaggtgttta
    16201 ggctacgcat atgatacgta gtaaatacgt aagtaaccac ataaaaagta agaaaaaaat
    16261 caagtacagt tatattgtga ttaagaaacg tgcacatttg ttagtcgaaa tacttatgaa
    16321 agaaggaaat atttatgtta aagattttta atcgtaaaga agccgttaat ggagtaatat
    16381 tcattaagtc aataaaagat ttgaacacag taattaatgt agctaaagat attggtaagg
    16441 aatgcaaaag gagaggttta aatgtagagt attgtttttt ggacacaagt gaagataatg
    16501 taatcgaaag aaaagcaatt aagcagtttt tagatgaaat gcaggataaa aacattaatc
    16561 tggttgtgtt aagaactctg gatgatataa gtaataatcc tatcgaaaga gaagcatttc
    16621 ttacagtcat gaatgataat ggagtaggaa tttatctttt tgaggaagga tgtttcgcta
    16681 tggtcaacta taattttgaa taataaaccc tatgttaggc agacatatcg ttgtctgctt
    16741 aacataatag gatacagatg aatgtatgga ggaggcaaca tattgaaata tgaaggatgg
    16801 aatgttggtt caactattcg aagattgaga aaagaaaaaa atatgacgat agaagaatta
    16861 agtgaagctg taggcaaaag tccttcgcat atagcacaaa tagagcaggg ctctagaagg
    16921 ttaggtatta atctgcttta cgaattaata acggtattag aaactgatgc aaatacaatt
    16981 ttggttgtcc atagaaagaa ttcggattta tcaattgata aagaattaat gaagttgaca
    17041 ccgaaagtaa gaatatattt tcaaaagcag tttcttaata tgatagaaga gtttccgatt
    17101 aagtaagaaa ggtaaaaggt atgggaaaga aaaatagaac aattaaggta attgcatatt
    17161 tgtcagttgt aaatgcaaca gaaaagaatg tggaatggaa ggaagacaag caactgagat
    17221 acataagaga gtatgcaaaa gcacattgca ttagaatagt aaagatatta cgtagaaaca
    17281 tattaggtaa aaatgtacgt gatgcacaat ttagaaaaat gattggagcc atagaatgcg
    17341 ggatggttga tggtattata gtatgtaaaa tggctttaat atctgacacg gttgttgatg
    17401 cgtataagaa agttggagac gtggtgcagg caggtggaca tatgataact gtagatgaag
    17461 gagagttaaa tcttcctcta aaaatgtaaa ggagatataa ctatatgaga cagattatga
    17521 ggggagatgt gatatatgtg gatttgggac aacatccaaa tagttccatt cagtcaggca
    17581 ttcgtccctg tgtagtaata agtaataacc aaaataacaa atattcaaaa gtaatttcag
    17641 tttgtccctg tacaggaaga gtaacgaaga agaaagtgat aacacatatc ttagttacta
    17701 cgaaagatgt aaatggatat tttcaaaaga actcaatatt attaattgaa caaattaccg
    17761 tggttgaaaa gaaacaaata ataagtaagg taggtcatat tccacgagat tcagaggtta
    17821 tgaaaaaagt taattgttta attaaaaagc aattgggagt tgactaaata atagaattaa
    17881 taaaagtaaa gattcaaaat gaggtggagg aagaaaaagt gaatgaaaac actaatgtta
    17941 tcgaaccagc attactaaca ttggagcagg cttgcaaata tttgtgtatt ggaaagacat
    18001 cttgcagaaa gttgtttaaa gagcatgaac atgaatttgt tgtacgaatt gggaataggc
    18061 tatatgcaaa taaatcacta ttggataaat ggattgatga tcaaaccagg gcttaaaaga
    18121 ggaataacta aatagtaatg cttgagaaaa aggagaaaag aaaatttaga aatataaagc
    18181 gattattgta ttgaaaaaga gagcaaactt tgctataata cgaatagaac gtttgttctc
    18241 taaattacat ttcgcagaaa ggagaacaaa tgggcaaaaa aacattagta aaaactaaaa
    18301 aagagccaaa tataagaagg cgttcaaatg gcttatggga agcgagaaag cagattaatg
    18361 gaattccaat tcgtgttacc gggcatgata agaaacaggt attagctgaa tttgacaaaa
    18421 aagttgaaga agctgaaaat ccagcactta ttagtagtga tattacggtt gatgcgttta
    18481 gagacaaatg gtttaataca tttaaggttc ctaaaattaa aactacaagt atatatccta
    18541 tgactagaag atatgaaaga acttttggta atagaattgg taaaagaaag ttgaatagct
    18601 taacttgctt tgacatacag gtagctatta atggaatgtt aagtgatgga ataggtatca
    18661 ccacaataaa agatgctctt ggaagtttca gagaatgtct tgaatcagct aagaataatg
    18721 gattgattgc tataaatccc tgctttgaaa ttattcttcc tgaaaagaca aatagtaagc
    18781 aaagacgatt tttaactgta gatgagcaaa agaggttttt ggaaacagct gaaacagaat
    18841 atggttggta ttaccctatg ctgaaagtta tgttgcttac aggaatgcgt attagtgaag
    18901 tgggcggatt atgttggtca gatattgatt atgataatga tgtaattcat attagaagag
    18961 cattatttag tcaatatgaa tatggtaaaa agaaattaca ttttacaact acaaagacta
    19021 ttaattcggt aagagatatt ccaatgatgg cagattgtaa aaaaatgttg agacttcaaa
    19081 aaaagaatca gaataagata aaaaaggaat taggaaaaag atatagaagt gaaaatgaag
    19141 aaggattatc tgatttagta tttacatcat ctatgggctc agcagcaaca agatataatg
    19201 ttgcaccaat tataaataag attgtaaaat caattaattt gagagaagat tatgagtctg
    19261 taaaagaaaa tcgtaaaccg atatatatgg agccggtttc accccatgct cttagaagaa
    19321 cattttgtac aagatgtttt gaagcaggta tgaacataaa ggttgttcag aaaattatgg
    19381 gacatagtaa ctatgcagtt acagcaaata tatatacaga agtaatgccg gataaaatga
    19441 atgaagaagt tgaacttttt aattctaagt tattgacaat gtaaagaatt tggtccaact
    19501 tttgcaatgg accaaatact catagacttg aaaatggtag agaaaatagt tttgctaatg
    19561 tgaagagaga gtcgttcaac ttaaaagttg gaccagaaaa aattatatat agtatttctt
    19621 actgcattga aggagaataa taaaaaaagt tatcacttca gatgaaataa atcgtaagtt
    19681 atcataactt gattttataa aaaagaattc tattttataa cgggtgaaaa cccacattat
    19741 agaggagaaa atcccttaaa tgtactattt ttagtatgtt tgagggattt ttttggctct
    19801 ttgtcaagag tgggaataaa aaaattataa aaatatcaaa tagaaaaaca aaaaacacaa
    19861 aaaatatgtt tgacttctcg aagtgaatct ttcaaattaa aattgataga atgatgtata
    19921 tatggtaaaa taactatagt taaatatcta attggacaaa aaagaattcg aatgaaaaaa
    19981 cactggtaaa gtagtggatt taatgaagag gtagcgcata tgtcagtatc atataatgga
    20041 ttatggaaac tattgattga taaaaatatg aagaagattg atttgacaaa taatctcggt
    20101 ataagtagta gtacagttgc caaaatgaca aagggtgaga aggtatctat gaatattctg
    20161 gaaaaaattt gtgatgaatt agattgtgat tttggagatc ttatccacta tgaaaagaat
    20221 aaagatggtg gaaaggatga attataaaat atagcacagg attaacgtca aacttgcttt
    20281 ggctacaaat actggtatga aaaagcgtat agaagtgttg ttaaagataa agaattgcaa
    20341 gtttaagttt tgaaagaaat tgaattaata aagatataag caggaggttt gacgattgaa
    20401 agataatatt ttagaagaat taaatcttaa agaagatcat gatcgagaat gcaagctggc
    20461 aaccggtgga cttccggaaa gtatatggga aacatattct tcctttgcga ataccaatgg
    20521 tggaactatt cttcttggaa taaaagaaca tagagattca tttactgtgg aaggtttgac
    20581 ggaaa
//
