LOCUS       NZ_CP092643.1          19730 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP092643.1 Agathobacter rectalis strain VPI 0990 chromosome,
            complete genome.
ACCESSION   NZ_CP092643
VERSION     NZ_CP092643.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:46:22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1215766
            Orig. end    :: 1235496
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..642
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 168.3; E-value:
                     3.6e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1157"
                     /transl_table=11
                     /translation="MIQLQNVTKRIKENTVLDNVSYTFKSGFVYGLYGQNGSGKTMLLR
                     AISGLINLDSGSIFIDGEKLHDKIEFPPETGIVIENMELLPECSAKRNLQMLAKIKNIA
                     DEKDISFSLERVGLDPDSDKKVKKFSLGMKQRLNIAQAIFENQKIILLDEPTNALDEDA
                     VQLIYKIIREEKSRGATIIVATHHKEDLKEVCDVILKIAEGKIVEENENK"
     protocluster    1..19730
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1225043:1225776]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9278..10010
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..19730
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..19730
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="3"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     PFAM_domain     49..471
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1157_0041"
                     /evalue="2.10E-29"
                     /label="ctg1_1157"
                     /locus_tag="ctg1_1157"
                     /protein_end="157"
                     /protein_start="16"
                     /score="102.9"
                     /tool="antismash"
                     /translation="LDNVSYTFKSGFVYGLYGQNGSGKTMLLRAISGLINLDSGSIFID
                     GEKLHDKIEFPPETGIVIENMELLPECSAKRNLQMLAKIKNIADEKDISFSLERVGLDP
                     DSDKKVKKFSLGMKQRLNIAQAIFENQKIILLDEPTN"
     CDS             617..1153
                     /locus_tag="ctg1_1158"
                     /transl_table=11
                     /translation="LLRKMKINKYFLGIILIIIIIMYFMAGVLFLGNTREDNNMKVSTE
                     QQRIEYQTFKSETEGYSLASKYAENLQNNSLDKEAINLQLQEAKKFLQDNIKGISRESD
                     NFAQMFYYCGIIYGLDSIYNCGDYEFVKVGIEVRKYIIKVQNGDMDDELEADLYDKLTK
                     LTADDIQEVVEAIDN"
     CDS             1409..1699
                     /locus_tag="ctg1_1159"
                     /transl_table=11
                     /translation="MVTTESVTIKVPVGMSKYLVTMNPETELTRNALLLYPYILNQTIS
                     HGRAAEILGIRKSELIDLYDKLGYSYFDMTMDDLDDELNTFRELKKKEAAV"
     CDS             1696..1830
                     /locus_tag="ctg1_1160"
                     /transl_table=11
                     /translation="MIVVSDTTPLRLEADEIRQKKFIVVKPVNNPESASIYIKKSGRS"
     CDS             2169..2525
                     /locus_tag="ctg1_1161"
                     /transl_table=11
                     /translation="LKIVVNLTSVPFVLGLIVELEDCYIVTSNRESGFGRYDVMLEPRD
                     KCDDAFIIEFKVQDSETEKDLEDTVKAGLEQIEYKKYAATLEARGIPEEKIHKYAFAFC
                     GKHVLIGKSTTGDK"
     PFAM_domain     2208..2501
                     /aSDomain="PDDEXK_9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08011.13"
                     /description="PD-(D/E)XK nuclease superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1161_0042"
                     /evalue="5.40E-17"
                     /label="ctg1_1161"
                     /locus_tag="ctg1_1161"
                     /protein_end="111"
                     /protein_start="13"
                     /score="61.7"
                     /tool="antismash"
                     /translation="LGLIVELEDCYIVTSNRESGFGRYDVMLEPRDKCDDAFIIEFKVQ
                     DSETEKDLEDTVKAGLEQIEYKKYAATLEARGIPEEKIHKYAFAFCGKHVLIG"
     CDS             3516..4160
                     /locus_tag="ctg1_1162"
                     /transl_table=11
                     /translation="MLIVREFSNRFQQMSGMPINSNETKERLKAAGIDINSKQYRAVMS
                     EMSRDGGGGYTTISAIKKRMSRYDKDGDWINPRTGLAGLLVTDKNCASKNRIVSISESI
                     MDEMFESTKKEFFMENGVHNGDTTNRSEIYQKLYQQTEKNDRLAAGYTLEEYERQYWQA
                     FTDAVKVADPKWEAGKPIMPGVLDRITSKSIDALLVKSGSQLIRKSFERMI"
     PFAM_domain     3570..4103
                     /aSDomain="DUF3879"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12995.9"
                     /description="Domain of unknown function, E. rectale Gene
                     description (DUF3879)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1162_0043"
                     /evalue="1.10E-100"
                     /label="ctg1_1162"
                     /locus_tag="ctg1_1162"
                     /protein_end="196"
                     /protein_start="18"
                     /score="334.9"
                     /tool="antismash"
                     /translation="INSNETKERLKAAGIDINSKQYRAVMSEMSRDGGGGYTTISAIKK
                     RMSRYDKDGDWINPRTGLAGLLVTDKNCASKNRIVSISESIMDEMFESTKKEFFMENGV
                     HNGDTTNRSEIYQKLYQQTEKNDRLAAGYTLEEYERQYWQAFTDAVKVADPKWEAGKPI
                     MPGVLDRITSKSIDA"
     CDS             4230..4682
                     /locus_tag="ctg1_1163"
                     /transl_table=11
                     /translation="MNTIKKRALTSIAVCFMACLMFSMPVLAASNSFSKTTVKLNAIDG
                     GVSQIAKVSSGSVLGTNPKITQVKVYLNVASGTDPFDLYIESPEGTVARLTPSTKSRTY
                     YVTDFVCENPKGDWYLQIENLGKTYDPNKLYPASTVTATITVTYSY"
     CDS             4936..5526
                     /locus_tag="ctg1_1164"
                     /transl_table=11
                     /translation="MRTKKFIVALCFSFFMFMCSVSTVYAYNTYNQHKLTYGVGNYGKD
                     TQHYFITSSASGYASYINTAMSEWVNTTSSMGVTTPISYTKTTTQSSSRMDIYQVSTVN
                     EWWGLTTMYNGSTEVDPFSSNWAWGKIQLDADFSDLSENKRLAVIAHEMGHVMGLAHSD
                     FSNVLMRADIAYNSSSTSRAQTNDLGGINYLYK"
     PFAM_domain     5308..5520
                     /aSDomain="Peptidase_M10"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00413.26"
                     /description="Matrixin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1164_0044"
                     /evalue="2.00E-09"
                     /label="ctg1_1164"
                     /locus_tag="ctg1_1164"
                     /protein_end="195"
                     /protein_start="124"
                     /score="37.5"
                     /tool="antismash"
                     /translation="NWAWGKIQLDADFSDLSENKRLAVIAHEMGHVMGLAHSDFSNVLM
                     RADIAYNSSSTSRAQTNDLGGINYLY"
     CDS             5538..6320
                     /locus_tag="ctg1_1165"
                     /transl_table=11
                     /translation="MKKIGIRILGCMALLSMVGCGRIEGASVQDLSNTKDAIVESETTL
                     AENNNEYSNKNSLFYSDISSYEIFTDVNSEAALKNLYYNIDEFIDSDSSDVIVKGNIIE
                     IEYVYIDGCSYSVLTVDVERAYKGEVQETITVYEDGGYTRLSDEKEQIEAHADLSQYTE
                     EEMENLLINHTFMGAEHSNVGDTVILFLKTNEGSILGDSYRINCSVFGRYTLNKDSYIR
                     PEFIVENDNPEKITTYSNMDTFEFSVSKSMLEDKLSQQ"
     CDS             7125..7850
                     /locus_tag="ctg1_1166"
                     /transl_table=11
                     /translation="MFRIAICDDEKIFRDDLKEILIRYMTDRGIMLEIDTFSSGKEFVE
                     LGIEMVKYKIVFLDINMDELDGIMTAKKIRENSKDMFIVFVTAFVNYTIEGYKVDAVRY
                     ILKDNKNLVASVYECMDAIHEKMDYKITWAEFDFCEGTRKVSLNRILYIESKLHKLEFH
                     VMEDCLQKYTLQGTLNEIDDKFAGNDFLRIHQSFLVNMKFIKNISRYRVLLNNGILLDI
                     ARARYKYVEEKFIAYRGEV"
     PFAM_domain     7134..7451
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1166_0045"
                     /evalue="1.70E-16"
                     /label="ctg1_1166"
                     /locus_tag="ctg1_1166"
                     /protein_end="109"
                     /protein_start="3"
                     /score="60.4"
                     /tool="antismash"
                     /translation="IAICDDEKIFRDDLKEILIRYMTDRGIMLEIDTFSSGKEFVELGI
                     EMVKYKIVFLDINMDELDGIMTAKKIRENSKDMFIVFVTAFVNYTIEGYKVDAVRYILK
                     DN"
     PFAM_domain     7548..7823
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1166_0046"
                     /evalue="1.50E-15"
                     /label="ctg1_1166"
                     /locus_tag="ctg1_1166"
                     /protein_end="233"
                     /protein_start="141"
                     /score="57.3"
                     /tool="antismash"
                     /translation="TRKVSLNRILYIESKLHKLEFHVMEDCLQKYTLQGTLNEIDDKFA
                     GNDFLRIHQSFLVNMKFIKNISRYRVLLNNGILLDIARARYKYVEEK"
     CDS             7851..9170
                     /locus_tag="ctg1_1167"
                     /transl_table=11
                     /translation="MFVYIQSLLIMMLEILCCKIFFEAFGIKREENNCWKNYSIVIGLT
                     VLCYFIAMIFRDYFIVKQVFSIILITFFMLLYLKLSFGKAMILSALFESLLLVMDYFAL
                     LMNIYIFHNMEEVWESHVIQGSLVVVLGKALLLFAVLIIRNHMEKKSLAMLADTEWLRF
                     IFFPIFTICVITAMIKMSEDIKNKAQENLFFVIACGLAGMNIVVFYLIYDILKRENKLQ
                     EERIYRIQVKNQIGMYRSISENFDKQKKMTHEYKNQIMCIDSLIKKKKYDSLESFVNKI
                     SGQISKELDFICTNNVIVDAVLNTKYQEIRDKGIVFVFKINDLSSLNISDEDVVVIMSN
                     LLNNAIEACEKCRGDKIIKLKIVIEDNNAIISVKNTYENAVIYENGEIQTTKILDTDEH
                     GIGIKNIAETIRKYGGSYVIQNDEREFYFSIMIPLVKSDF"
     PFAM_domain     8835..9149
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1167_0047"
                     /evalue="2.40E-25"
                     /label="ctg1_1167"
                     /locus_tag="ctg1_1167"
                     /protein_end="433"
                     /protein_start="328"
                     /score="88.5"
                     /tool="antismash"
                     /translation="ISDEDVVVIMSNLLNNAIEACEKCRGDKIIKLKIVIEDNNAIISV
                     KNTYENAVIYENGEIQTTKILDTDEHGIGIKNIAETIRKYGGSYVIQNDEREFYFSIMI
                     P"
     CDS             9278..9871
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1168"
                     /sec_met_domain="AgrB (E-value: 1.5e-32, bitscore: 110.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEKMAMGLVDQMAEEKMIDKEAEEYYVYTLVSLMEKFITIGTIL
                     LISVLIEKLVPTAFFLLFFLSLRKRTGGYHMNTFFQCYLGTVVTYMLVLGLCMVLVDYP
                     QLVFGLLLVAICIVEVIGTVNHPNIHMDAVELSESKRAARILCAVEVCVIYTFTLLGAD
                     MMYVCHMAVAVILCAVLLLIAKILKQEVKRNEEN"
     PFAM_domain     9302..9826
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1168_0048"
                     /evalue="4.00E-31"
                     /label="ctg1_1168"
                     /locus_tag="ctg1_1168"
                     /protein_end="183"
                     /protein_start="8"
                     /score="107.9"
                     /tool="antismash"
                     /translation="LVDQMAEEKMIDKEAEEYYVYTLVSLMEKFITIGTILLISVLIEK
                     LVPTAFFLLFFLSLRKRTGGYHMNTFFQCYLGTVVTYMLVLGLCMVLVDYPQLVFGLLL
                     VAICIVEVIGTVNHPNIHMDAVELSESKRAARILCAVEVCVIYTFTLLGADMMYVCHMA
                     VAVILCAVLLLI"
     CDS             9858..10010
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1169"
                     /sec_met_domain="TIGR04223 (E-value: 0.00015, bitscore:
                     19.4, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKINKKVLKVVERVIRNEIKRASGDPPFCLGIFHQPKRPVEHKC
                     NRENK"
     aSDomain        9936..9983
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1169_0014"
                     /evalue="2.10E-04"
                     /identifier="TIGR04223"
                     /label="ctg1_1169"
                     /locus_tag="ctg1_1169"
                     /protein_end="42"
                     /protein_start="26"
                     /score="19.4"
                     /tool="antismash"
                     /translation="PPFCLGIFHQPKRPVE"
     CDS             10311..10853
                     /locus_tag="ctg1_1170"
                     /transl_table=11
                     /translation="MKICYIVVSAFLIIFYPRQLTHLMCFGRHRDKNIVKSKAAYWGIY
                     LFWTIIFLIGCLMMGSAMKVNSTMDKLVYYFILGSDNRDCVELGSEENDEAYISTYYTR
                     KEINESFLFEVVQKHEYAYEMCQLQELIIKKQDERWILYLNDEVMGYVEVKKGFLIKEF
                     CFVWDRQKIDQRRQLYE"
     CDS             10846..10968
                     /locus_tag="ctg1_1171"
                     /transl_table=11
                     /translation="MSKKMCKRIFSVILSLGLVMVQSMNVNAAGNEIGKYSVFV"
     CDS             complement(11152..12189)
                     /locus_tag="ctg1_1172"
                     /transl_table=11
                     /translation="MIDNYEHYITKNIKAFYKRRLFSPIVYIILLTVLWFAFSLGDILS
                     PIHIDDSVSFEAAYKDSDRYVKTTLKKLYFTGYTMKDGNDIKGYYYYCMRDKHCSIVLL
                     APSTCEEGLPSIDKLTVVGKIVKGKGTYTQFVNKLSKDLSWDSKGLSDTITGYYLNEPE
                     YHLKTTIFMFVFYFGTLIYAVISLIFYILCIRFPVLAPACQNLVVFGNPHKLLAEAEEE
                     LATLPQLATEDMFITEHYFIMTSPYGNAIVPIKEILWIYKYSTLHKILWYHFSISYTLH
                     ISANKHLYIHCPKNTKSDIDGIIDYLAEANHDILVGFSEENRLKVQAVQGKPLHIERLL
                     AWKKK"
     CDS             12293..13042
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 133.2; E-value:
                     1.9e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1173"
                     /transl_table=11
                     /translation="MEAYTSFARVYDMFMDNVPYEKWSRYIVEKLRANGIDSGYVVDLG
                     CGTGKLTTLLADAGYDMIGIDNSFDMLDMALEREDDRILYLMQDMREFEPGEKVSAVVS
                     ACDSINYILEPEDLQAVFFCVSESLKEGGIFIFDINTPYKYEVLMADNTIAENRDEGSF
                     IWDNYYDADEKINEYDLTLFIKEQSEDEDDIYKKFEETHFQRCYEISELKELLEQSGLV
                     FDAVYDAYTDNQVKCDSEKVTLIAHKA"
     PFAM_domain     12413..12691
                     /aSDomain="Methyltransf_25"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13649.8"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1173_0049"
                     /evalue="3.10E-13"
                     /label="ctg1_1173"
                     /locus_tag="ctg1_1173"
                     /protein_end="133"
                     /protein_start="40"
                     /score="50.3"
                     /tool="antismash"
                     /translation="VVDLGCGTGKLTTLLADAGYDMIGIDNSFDMLDMALEREDDRILY
                     LMQDMREFEPGEKVSAVVSACDSINYILEPEDLQAVFFCVSESLKEGG"
     CDS             13066..13932
                     /locus_tag="ctg1_1174"
                     /transl_table=11
                     /translation="MSDYIVRATAADANIRAFAVTSKEMVENAREDHMTTPVMTAALGR
                     LLSAGAMMGAMMKGDKDIITLQIQCSGPAKGLTVTADSHGNVKGFAMNPQVELPLNAAG
                     KLDVGGALDLGILTVIKDMGLKEPYSGQCELKTGEIAEDLTYYFATSEQIPSAVGLGVL
                     VDKDQSVKQSGGFIIQLMPFTPEDVVDRLEKKITEIDSVTQMLDRGLTPEQILEEILGD
                     FGLEITDTTETRFHCDCSKERVSRALSTLSKKDLDSIIADGESIEVKCQFCNKAYEFTV
                     DELKEMR"
     PFAM_domain     13072..13905
                     /aSDomain="HSP33"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01430.21"
                     /description="Hsp33 protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1174_0050"
                     /evalue="1.10E-90"
                     /label="ctg1_1174"
                     /locus_tag="ctg1_1174"
                     /protein_end="280"
                     /protein_start="2"
                     /score="303.8"
                     /tool="antismash"
                     /translation="DYIVRATAADANIRAFAVTSKEMVENAREDHMTTPVMTAALGRLL
                     SAGAMMGAMMKGDKDIITLQIQCSGPAKGLTVTADSHGNVKGFAMNPQVELPLNAAGKL
                     DVGGALDLGILTVIKDMGLKEPYSGQCELKTGEIAEDLTYYFATSEQIPSAVGLGVLVD
                     KDQSVKQSGGFIIQLMPFTPEDVVDRLEKKITEIDSVTQMLDRGLTPEQILEEILGDFG
                     LEITDTTETRFHCDCSKERVSRALSTLSKKDLDSIIADGESIEVKCQFCNKAYEFT"
     CDS             13933..15840
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294:Nitrilase/cyanide hydratase and apolipoprotein
                     (Score: 81.4; E-value: 1.1e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1175"
                     /transl_table=11
                     /translation="LKDGYIKVAAATPKVKVADTVYNGQLIKALMKECTDNGAKVVVFP
                     ELCITGYTCQDLFWQDKLIAAAEDELIGIADYSRSLDGIFFIGLPYEINGMLYNMAAVV
                     SRGEVLAMVPKTFLPNYNEFYEARHFASGENLSTYVTLKNGQQVSVDTDFIFSCKQLPK
                     LKIAVELCEDLWTPNPPSIRHAMSGATVIVNLSASDEVTGKAIYRRELVSGQSARLICG
                     YIYASAGDGESTQDVVYSGHNLICENGNVLAESGRFTNETIYSEFDVERIETERRRMTT
                     FVVEDDHRWAEFDLEVKDTTLSRYVNPAPFVPADKTDRDRRCDEILMIQAMGLKKRLEH
                     TNCKTAVIGISGGLDSTLALLVTVRAFDLLGKDHKDIAAVTMPGFGTTDRTYDNAVNLI
                     KCLGATFIEVDIKDAVNIHFRDIGQDPSVHDVTYENGQARERTQILMDIANKENGMVIG
                     TGDLSELALGWATYNGDHMSMYAVNASVPKTLVRHLVKYYADTCGSDLLESTLLDVLDT
                     PVSPELLPPENGKISQKTEDLVGPYELHDFFLYNMLRCGYAPAKVYRLARIAFEGKYDD
                     EFILKWLKNFYRRFFAQQFKRSCLPDGPKVGTVAVSPRGDLRMPSDACGRIWMDEVDKL
                     "
     PFAM_domain     13951..14754
                     /aSDomain="CN_hydrolase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00795.24"
                     /description="Carbon-nitrogen hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1175_0051"
                     /evalue="2.40E-17"
                     /label="ctg1_1175"
                     /locus_tag="ctg1_1175"
                     /protein_end="274"
                     /protein_start="6"
                     /score="63.2"
                     /tool="antismash"
                     /translation="KVAAATPKVKVADTVYNGQLIKALMKECTDNGAKVVVFPELCITG
                     YTCQDLFWQDKLIAAAEDELIGIADYSRSLDGIFFIGLPYEINGMLYNMAAVVSRGEVL
                     AMVPKTFLPNYNEFYEARHFASGENLSTYVTLKNGQQVSVDTDFIFSCKQLPKLKIAVE
                     LCEDLWTPNPPSIRHAMSGATVIVNLSASDEVTGKAIYRRELVSGQSARLICGYIYASA
                     GDGESTQDVVYSGHNLICENGNVLAESGRFTNETIYSEFDVERIET"
     PFAM_domain     14929..15429
                     /aSDomain="NAD_synthase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02540.19"
                     /description="NAD synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1175_0052"
                     /evalue="8.30E-32"
                     /label="ctg1_1175"
                     /locus_tag="ctg1_1175"
                     /protein_end="499"
                     /protein_start="332"
                     /score="110.3"
                     /tool="antismash"
                     /translation="GLKKRLEHTNCKTAVIGISGGLDSTLALLVTVRAFDLLGKDHKDI
                     AAVTMPGFGTTDRTYDNAVNLIKCLGATFIEVDIKDAVNIHFRDIGQDPSVHDVTYENG
                     QARERTQILMDIANKENGMVIGTGDLSELALGWATYNGDHMSMYAVNASVPKTLVRHLV
                     KYYA"
     aSDomain        14932..15423
                     /aSDomain="TIGR00552"
                     /aSTool="tigrfam"
                     /description="nadE: NAD+ synthetase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1175_0015"
                     /evalue="7.30E-26"
                     /identifier="TIGR00552"
                     /label="ctg1_1175"
                     /locus_tag="ctg1_1175"
                     /protein_end="497"
                     /protein_start="333"
                     /score="88.8"
                     /tool="antismash"
                     /translation="LKKRLEHTNCKTAVIGISGGLDSTLALLVTVRAFDLLGKDHKDIA
                     AVTMPGFGTTDRTYDNAVNLIKCLGATFIEVDIKDAVNIHFRDIGQDPSVHDVTYENGQ
                     ARERTQILMDIANKENGMVIGTGDLSELALGWATYNGDHMSMYAVNASVPKTLVRHLVK
                     Y"
     CDS             15857..16816
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1176"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.1e-09, bitscore:
                     33.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKTHKKTHRRQGSIKRARHRDRRMKIGAIVLCAAIIITTFLACG
                     MQLLVPVADAVVGADNKTQSRDVDVQKNNNSLTASKMDSEKKQNSSEADVNSAEQDSEP
                     DKETKLDEILHSAKYPGQLKELAKKNDEAIDFIYEYPKEHSIEHDIDLTAEASQDTVPL
                     LQQWDKRWGYEKYSGNYFAASGCGPTALSMVVLYLTHDAQASPLAVAEYAKEAGYSVDG
                     SGSAWNLISKGCRHYGVNAKTIKVDEDTFKERLDEGNLIVVNVGPGDFTEKGHFMVITG
                     YDDEGFTINDPNSIIKSNTHWQFERLGSQIRAAWRMFV"
     PFAM_domain     16334..16735
                     /aSDomain="Peptidase_C39_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13529.8"
                     /description="Peptidase_C39 like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1176_0053"
                     /evalue="9.10E-20"
                     /label="ctg1_1176"
                     /locus_tag="ctg1_1176"
                     /protein_end="293"
                     /protein_start="159"
                     /score="71.8"
                     /tool="antismash"
                     /translation="TVPLLQQWDKRWGYEKYSGNYFAASGCGPTALSMVVLYLTHDAQA
                     SPLAVAEYAKEAGYSVDGSGSAWNLISKGCRHYGVNAKTIKVDEDTFKERLDEGNLIVV
                     NVGPGDFTEKGHFMVITGYDDEGFTINDPN"
     CDS             complement(16959..17969)
                     /locus_tag="ctg1_1177"
                     /transl_table=11
                     /translation="MSKLTIPKNYSSALNLHDTQLAIKTVKDFFQGMLAQRLSLTRVSA
                     PLFVDPTTGLNDNLNGYERPVTFGILEQGDKEAEVVHSLAKWKRYALKKYGFSLGEGIY
                     TDMNAIRRDEETDNIHSIFVDQWDWEKIIRKEDRNLDFLKETVKTVYKCLRKTEQYMAI
                     QYDYIDLILPKDITFITTSELEEMFPDNTPKEREYYFAKAKGAICVMQIGDKLANGEPH
                     DGRAPDYDDWALNADIIVYYPVLDIALELSSMGIRVDEKALKEQLDKAGCPERAKLPFQ
                     KAILNKELPYTIGGGIGQSRICMFFLRKAHIGEVQSSLWPEETIKACEEHGIQLL"
     aSDomain        complement(16992..17912)
                     /aSDomain="TIGR00669"
                     /aSTool="tigrfam"
                     /description="asnA: aspartate--ammonia ligase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1177_0016"
                     /evalue="2.30E-97"
                     /identifier="TIGR00669"
                     /label="ctg1_1177"
                     /locus_tag="ctg1_1177"
                     /protein_end="326"
                     /protein_start="19"
                     /score="324.2"
                     /tool="antismash"
                     /translation="QLAIKTVKDFFQGMLAQRLSLTRVSAPLFVDPTTGLNDNLNGYER
                     PVTFGILEQGDKEAEVVHSLAKWKRYALKKYGFSLGEGIYTDMNAIRRDEETDNIHSIF
                     VDQWDWEKIIRKEDRNLDFLKETVKTVYKCLRKTEQYMAIQYDYIDLILPKDITFITTS
                     ELEEMFPDNTPKEREYYFAKAKGAICVMQIGDKLANGEPHDGRAPDYDDWALNADIIVY
                     YPVLDIALELSSMGIRVDEKALKEQLDKAGCPERAKLPFQKAILNKELPYTIGGGIGQS
                     RICMFFLRKAHIGEVQSSLWPEETIK"
     PFAM_domain     complement(17232..17912)
                     /aSDomain="AsnA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03590.17"
                     /description="Aspartate-ammonia ligase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1177_0054"
                     /evalue="1.20E-106"
                     /label="ctg1_1177"
                     /locus_tag="ctg1_1177"
                     /protein_end="246"
                     /protein_start="19"
                     /score="355.7"
                     /tool="antismash"
                     /translation="QLAIKTVKDFFQGMLAQRLSLTRVSAPLFVDPTTGLNDNLNGYER
                     PVTFGILEQGDKEAEVVHSLAKWKRYALKKYGFSLGEGIYTDMNAIRRDEETDNIHSIF
                     VDQWDWEKIIRKEDRNLDFLKETVKTVYKCLRKTEQYMAIQYDYIDLILPKDITFITTS
                     ELEEMFPDNTPKEREYYFAKAKGAICVMQIGDKLANGEPHDGRAPDYDDWALNADIIVY
                     YPVLD"
     CDS             18168..18581
                     /locus_tag="ctg1_1178"
                     /transl_table=11
                     /translation="MTFASAVLEAIDAILALAYIGLQIYYGVCYHIQVFKFVANILVLL
                     LVYIAITWLQHYPEKLNHIAAELCVGNIRKYSLRLLTFVKLVFTAGLLVPCVCDAFGIA
                     IRDVYSLIMIGLILVVTAYYEYRIFQEIKSLRK"
     CDS             18597..19730
                     /locus_tag="ctg1_1179"
                     /transl_table=11
                     /translation="MQLSIEEVKKLDSNSYQIIDIRSEEEVAHGAIKGALNIQAEEIES
                     DERVPHDKKLVIVCSRGKTSVDVAEYLTEKGFDAASLKGGYISWLLDAMKEDEVAERDI
                     KADVEQSIRKKFKKSIWRKFTKAINTYELVKPGDKIAVCISGGKDSMLMAKLFQELKHH
                     NKFDFDVKFLVMDPGYNEANRHVIEENCRNLGIPATIFESDIFDAVYDIEKSPCYLCAR
                     MRRGHLYAFAKELGCNKIALGHHYDDVIETILMGMLYGAQVQTMMPKLHSTNFEGMELI
                     RPLYLVREDDIKAWRDYNGLHFIQCACKFTDTCTTCNNEENRSKRVEIKQLIANLKKVN
                     PFVEANIFKSVENVNLATVVAYKKDGIKHSFLDHYDE"
     PFAM_domain     18615..18866
                     /aSDomain="Rhodanese"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00581.22"
                     /description="Rhodanese-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1179_0055"
                     /evalue="7.60E-10"
                     /label="ctg1_1179"
                     /locus_tag="ctg1_1179"
                     /protein_end="90"
                     /protein_start="6"
                     /score="39.4"
                     /tool="antismash"
                     /translation="EVKKLDSNSYQIIDIRSEEEVAHGAIKGALNIQAEEIESDERVPH
                     DKKLVIVCSRGKTSVDVAEYLTEKGFDAASLKGGYISWL"
     PFAM_domain     19014..19511
                     /aSDomain="ATP_bind_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01171.22"
                     /description="PP-loop family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1179_0056"
                     /evalue="4.10E-19"
                     /label="ctg1_1179"
                     /locus_tag="ctg1_1179"
                     /protein_end="305"
                     /protein_start="139"
                     /score="69.1"
                     /tool="antismash"
                     /translation="IAVCISGGKDSMLMAKLFQELKHHNKFDFDVKFLVMDPGYNEANR
                     HVIEENCRNLGIPATIFESDIFDAVYDIEKSPCYLCARMRRGHLYAFAKELGCNKIALG
                     HHYDDVIETILMGMLYGAQVQTMMPKLHSTNFEGMELIRPLYLVREDDIKAWRDYNGLH
                     FIQ"
ORIGIN
        1 atgatacaat tacaaaatgt aacaaagagg ataaaggaaa atacggtatt ggataatgta
       61 tcgtatacgt ttaaaagtgg ttttgtttat ggtttatatg ggcaaaatgg ttcaggaaag
      121 actatgctgc taagagctat aagtggtttg ataaatctgg atagtggaag tattttcatt
      181 gatggggaaa aactgcatga taaaattgag tttccacctg agaccggtat tgttatagaa
      241 aatatggaat tgctgccgga atgttccgca aagagaaatc ttcagatgct tgcaaagata
      301 aaaaatatag ctgatgaaaa agatataagc ttttctctgg aaagggtggg tctggacccc
      361 gactctgata aaaaagtgaa aaaattttca ttgggaatga aacaacgatt aaatattgca
      421 caggcaattt ttgaaaatca gaaaattata ttgcttgatg aaccgacaaa tgcattggat
      481 gaagatgcag tgcagcttat atataaaata ataagagagg agaagtcaag aggcgcaacg
      541 attattgtag ccactcatca taaagaagat ttaaaggaag tgtgtgatgt gatattaaaa
      601 attgcggagg gaaaaattgt tgaggaaaat gaaaataaat aagtattttc ttggaattat
      661 tcttataatc ataataatta tgtactttat ggctggagtt cttttcctgg gaaatacaag
      721 agaagataat aatatgaaag ttagtactga acaacagaga atagaatatc agacttttaa
      781 gtccgaaaca gaaggctata gtcttgcatc aaaatacgca gaaaatctgc agaataattc
      841 tttggacaaa gaagctatta atttacaatt gcaggaggca aagaaatttt tacaggataa
      901 tattaaagga ataagcaggg aaagtgataa ttttgcgcag atgttttatt attgtgggat
      961 catatatggg ttagattcta tttacaattg tggtgattat gaatttgtaa aggttggaat
     1021 tgaagtcaga aagtatatta ttaaagttca aaatggtgat atggatgatg agcttgaagc
     1081 tgacttatat gataagctga caaaactcac tgctgatgat atacaggagg ttgtcgaagc
     1141 aattgataat taaaacaaga taaaaatagc aaaaatctct ggacactgca acaaatggga
     1201 tatgtacagt tctaaattaa cccattcttt tgtagtgcat tgtaaaacat agcacgtcca
     1261 gaatagttcc aatacgcaca attttgacga ggaagattac ttgaataaaa gcagataaaa
     1321 atcagttgta gaaaatccaa ataatggata taataataat ataggaaaag agacgaacat
     1381 agatttctaa cagaaaggac gtgatattat ggtaacaaca gaatctgtaa ctattaaagt
     1441 tccggtagga atgtcaaaat atctggtaac tatgaatccg gaaacagagc ttactcgaaa
     1501 tgcactgttg ctgtatccat atatactgaa tcagacgata tcccatggtc gtgcggctga
     1561 aattctggga atcagaaaat ccgagttgat tgatctgtat gataagctgg gatattccta
     1621 ttttgatatg acgatggatg atctggatga tgaactgaat actttcagag aactcaaaaa
     1681 gaaggaggct gcggtatgat tgttgtatca gatacaacac cgcttcggct ggaagccgat
     1741 gagatcaggc agaagaaatt tatcgtagtg aagcctgtca ataatccgga atcagcaagt
     1801 atatatatta aaaagagcgg caggtcttga ccagggcgag agtgaagcga ttgtcctgtc
     1861 agatgaatta aaagcagatc tgttattgat ggatgaagca aagggaagaa atgtatcagc
     1921 tcagatggga cttagaatca tggggacgat agggattctt atggcagcct atgaggaaca
     1981 cgaactgaca tcggatgaag tcagagaatg cgtgaatggt ctgcaacgtg ccggacgaca
     2041 tatcggacag cggcattatc agatgctgtt aagcagattg aaagactaaa tatactctgg
     2101 ttctataata gtatcgtggt tctggattgg ttctaaaaag ttctgaaacg agatgcagga
     2161 tagaaaaatt gaaaatagta gtaaatctga cgtctgtacc atttgttctg gggctgattg
     2221 tagaactgga ggattgttat attgtgactt cgaaccggga gagtggattc ggaagatacg
     2281 atgtgatgtt ggagccaaga gataagtgcg atgatgcatt tattattgag ttcaaggttc
     2341 aggattcgga aacagagaaa gatctggaag atacagtgaa agccgggctg gagcagattg
     2401 aatataagaa gtatgctgca acgttggagg caagaggaat tccggaggaa aagattcata
     2461 aatatgcgtt tgcgttttgc gggaaacatg ttttgatagg gaagtcaaca acaggagata
     2521 aatagcaaaa atctctggac actgcataaa acaggagcct cgcaggagaa cttgctacaa
     2581 aattcgctgt acgaagcggc ttagcagctg ttggaattat gtcaagatac agcaatgggg
     2641 ctgtaaaaaa actcccctag aaaaaaatcg cccaggccgt gaggtctgag cgattttttg
     2701 gtataattaa ttatgctact aacagactat actaatggta attatactat gcgtcagctg
     2761 aaattaccat tagaaatcgc aaaattgatc gatatttctg atccggtata tactttttgt
     2821 gtccaatgta ttgacataga tccaatgctt tgtaccattg atggaaaaat tcaatcgcac
     2881 atatggtcat tatccgaaat atcaggttgc tgatgccgga tacggttctt acaataatta
     2941 tctttattgc gaagaacacg gcatggaaaa acacatgaaa tttcccatgt acaaaaaagc
     3001 aacgacagac gaaagctgaa taaaactcaa gcgtgattag ctgagcttta ttaaattcac
     3061 cattttttat acccaaagat gcagacctgt tcaaaaatag aaaaattcat acaaagaaac
     3121 aacaaaaccg acatttgccg gagttggcgt ttcttaatta gggacttatt ttacagcccc
     3181 attaaattat agctgaatca ttataatata tgagatgata cctataacac tataaaagca
     3241 atgaatgaga gtatgacagc aaaatctatg cctgttatgg ttggaaagaa acgataagaa
     3301 gatattcctt gaattgaact ttggtttgat tcaagggaat tttatatttg gagtgtcatt
     3361 ttctgcaatt aggagtcact ttctgcaaga acaattgaac aatacaattt atttgatata
     3421 tttaaagaag aaagtgatat ttaatttgac aagagtataa tcgtttgtta aagaagaaaa
     3481 tggatttcag agtaatttat caaggagaga aaattatgct tatagtaaga gagtttagca
     3541 atagatttca gcaaatgtct ggaatgccta tcaatagtaa cgaaacaaag gaaagactta
     3601 aagcggctgg aatagatata aatagtaaac aatatcgagc tgttatgagt gagatgtcca
     3661 gagatggtgg cggtggatat actacaatct cagccattaa gaaacgaatg agccgatatg
     3721 ataaagatgg agactggatt aatccacgca caggattggc ggggttactc gttacagata
     3781 aaaattgtgc tagcaaaaat agaattgttt caatttcaga aagcattatg gatgagatgt
     3841 ttgaaagcac taaaaaagaa ttttttatgg aaaatggggt gcataacggc gatacaacaa
     3901 acagatcaga gatatatcaa aagttgtatc agcaaactga gaaaaacgac agattagcag
     3961 cagggtatac attagaggag tatgagcgac agtattggca ggcattcaca gatgccgtaa
     4021 aagtagcaga ccctaaatgg gaggctggaa aacctatcat gccgggagtt ttagatagaa
     4081 ttacaagtaa atccattgat gctttattag taaaatctgg tagtcaactg attagaaagt
     4141 catttgaacg aatgatataa aaagtatcca ttttgcggga gagcattctg tttgataata
     4201 tttatgtttt gacttaagga ggatttttta tgaatactat taagaagaga gctttaacat
     4261 caattgcagt atgttttatg gcatgtttaa tgttttcaat gccggtatta gcagcttcaa
     4321 attcattttc gaagaccact gtaaagttaa atgcgataga tggtggggta tctcaaatag
     4381 caaaagtttc ttcaggaagt gttttaggaa ccaatcctaa aatcactcag gtgaaagtat
     4441 acttaaatgt agcaagtggt acagatccgt ttgaccttta tattgagagt ccagaaggaa
     4501 cagtagcaag gttgacacct tctacaaagt caaggacata ttatgtaacc gattttgtgt
     4561 gtgaaaatcc caaaggagat tggtatcttc aaattgaaaa tttaggcaaa acctatgatc
     4621 ccaataaact atatcctgca tcaacggtaa cggcaacaat aacagtcaca tacagttact
     4681 gatttaatat caataggatg acattctcgc aagtaaataa tgatttgttc atttgcaaca
     4741 tgttaaacac gatacttttt tagaggataa aggttttggg ttttacaaaa aaaggcacca
     4801 tttacaaagc caattgaccc ttgaattgtt gtcaattata gttgtcaaaa aatacggagg
     4861 tgagataaaa aattttagta gtattttgtt gctttataat tgtatgtatt aagaaaatta
     4921 agcggagaaa gttttatgag aacaaaaaaa tttatagttg cattatgttt tagctttttt
     4981 atgttcatgt gtagtgtgtc aactgtgtat gcgtataata catataatca gcacaaattg
     5041 acatatggtg tgggaaatta tggaaaagat acacaacatt actttattac atcaagtgca
     5101 agcggctatg catcttatat taatacggca atgagcgaat gggtaaatac aactagtagc
     5161 atgggagtaa caacccctat ttcttataca aaaaccacaa cacaatcaag tagtagaatg
     5221 gatatatatc aagtaagtac tgttaatgaa tggtgggggt taacaactat gtataatgga
     5281 agtacagagg ttgatccatt cagtagcaat tgggcttggg gaaaaataca attagatgcg
     5341 gatttttcgg atttaagtga aaataaaaga ttggctgtta tagctcatga aatggggcat
     5401 gttatggggt tggcacattc agactttagt aatgttttga tgagggcaga tattgcttat
     5461 aattcaagta gtacctcgag agcacaaact aatgatttag gtggaataaa ttatttatat
     5521 aagtaggagg aagtaaaatg aaaaaaattg gtattagaat attagggtgt atggcattat
     5581 tgtcaatggt tggttgtgga aggatagaag gtgcaagtgt tcaggattta agcaatacta
     5641 aagatgcaat tgttgaaagt gaaaccactt tggcagaaaa taataatgaa tattcaaata
     5701 aaaattccct attttatagt gatatttcta gttatgaaat ttttacagat gtaaatagtg
     5761 aagctgcgtt aaaaaatctt tactataata ttgatgaatt tattgatagt gactcatcag
     5821 atgtcattgt aaaaggaaat attatagaaa tagaatatgt gtatattgat ggatgttctt
     5881 attctgtgct taccgttgat gtggagagag catataaagg cgaggtgcag gaaaccatca
     5941 ctgtgtatga ggatggagga tatactcggc tgagcgatga aaaggaacaa attgaagcac
     6001 atgccgattt gtcacaatac acagaagaag aaatggaaaa tttgctaatt aaccatactt
     6061 ttatgggtgc ggaacattca aatgttggag atactgttat tctatttctg aaaacaaatg
     6121 aaggcagtat tctgggtgac agttatcgaa ttaactgttc agtctttgga cggtacactt
     6181 tgaataaaga tagctatatt agacctgaat ttattgttga gaatgataat ccagagaaaa
     6241 taacaacata tagtaatatg gatacattcg agttttcggt gtctaaatca atgcttgaag
     6301 ataaactttc acagcagtaa aatgtctata ttgaaaatat tggaaaaaag taaatgtttg
     6361 atataacaga ctatcaaaga aaattatgca ttttttctat ggggtattct tgcaacagtg
     6421 atgtaattta ataggcacag gaatatgtca aaagaccaaa acagaaagtg ttaatgataa
     6481 taggtgttta ctgttataac atttgttatt taaagggact gtcgctttaa cgatttagca
     6541 tgacagcccc tttttcgaat ctctttttta aaatattata gggaagaaac aagatggact
     6601 agaacaagtc ccttttcatc atgcatattg cataaaataa tgcaaaaaga accaaaatgg
     6661 gttcataggc atggtgaaaa gggatggaac agaaaataaa gcaagatgag atatttattg
     6721 gtaagaatat ccggcgtata aggaaagaaa gaggaagaac atttgctaaa gagatataat
     6781 tatattcttt aagttcggag acagtagtaa tgccggcata tgttaatgca aatttggtaa
     6841 tagaagaaag attaagctgt tcaaaatgtt gattttggtc attttctaca aatataggtc
     6901 gatttctgcc ttttatttga ttgttcgggt gagaaatagt aatatatgac tgtaaaatgg
     6961 ttttatatta ttctaattga acgagggaaa ataagctatg tttatatgga agtaaataaa
     7021 gtttttgttg gaaggtgcca aaatataaaa atatgtacaa aattaaaaaa acacaaccaa
     7081 ccaaacgagg aaatatgcaa aatttagaga ggggggaaaa acgtatgttt agaattgcta
     7141 tatgcgatga tgaaaagatt tttagagatg acctaaagga aatacttata cgttatatga
     7201 ctgacagagg aataatgctt gaaattgata cttttagttc aggaaaagaa tttgttgaac
     7261 tgggaattga aatggtaaaa tataagattg tttttctgga tatcaacatg gatgaactgg
     7321 atggaattat gacagcaaaa aagatccggg aaaacagcaa ggatatgttt attgtttttg
     7381 ttacagcctt tgtaaactat acgatagaag gatataaggt agatgcagta agatatattt
     7441 taaaggacaa taaaaatctg gttgccagtg tttatgagtg catggatgca attcatgaaa
     7501 aaatggatta taagattact tgggctgaat ttgatttctg cgaaggtaca aggaaagttt
     7561 cattgaatcg catattgtat attgagagta aattacataa attggagttt catgtaatgg
     7621 aggattgtct gcaaaaatat acattacaag ggacgctaaa tgaaatagat gataagtttg
     7681 ccggaaatga ttttctgcgg atacatcaga gctttctggt taatatgaaa ttcattaaaa
     7741 atataagcag atacagagta ttgctgaata atggaattct attagatata gctagagcga
     7801 gatataaata tgtagaagaa aagtttatcg cttatagagg tgaagtataa atgtttgttt
     7861 acattcagag tcttttgatt atgatgttgg aaatattatg ctgcaaaatt ttttttgaag
     7921 catttggaat aaaaagagag gaaaataatt gttggaaaaa ttatagtata gttatcggat
     7981 tgacagtgct ttgctatttt attgcaatga tttttcgaga ctattttatt gtaaagcagg
     8041 tattttcaat tattctcata acattcttta tgttgcttta tcttaaactg agttttggta
     8101 aggcgatgat tttatcagca ttatttgaga gtcttttgct cgtgatggat tatttcgcgt
     8161 tacttatgaa tatttatatt tttcataaca tggaagaagt atgggaatca catgttatac
     8221 agggttcatt ggtcgttgtt ttaggaaagg cattgttact ttttgctgta ttaattatta
     8281 gaaatcatat ggagaaaaaa tctttggcta tgctggcaga tacagaatgg cttcggttta
     8341 tttttttccc tattttcaca atatgtgtta ttacagctat gataaaaatg tctgaagata
     8401 taaaaaataa agcccaggag aatttatttt ttgttatagc gtgtggattg gcgggaatga
     8461 acatagttgt attttattta atatatgata ttttaaaacg agaaaataaa ttgcaggagg
     8521 aacgtattta taggatacag gttaaaaacc aaataggtat gtatcgttct atttctgaaa
     8581 attttgataa acaaaagaaa atgacacatg aatataaaaa tcagattatg tgcattgatt
     8641 ctttgataaa aaagaagaaa tatgattcat tggaaagctt tgtaaataaa atcagtggtc
     8701 aaattagtaa agaattggat tttatttgta caaataatgt gattgtggat gcggtattga
     8761 atactaaata tcaggaaata agggataaag gtattgtttt tgtatttaaa attaatgatt
     8821 tatcatcttt gaatattagc gatgaggatg ttgtggttat tatgtccaat ttattaaaca
     8881 atgcgattga agcatgtgaa aagtgcagag gggataaaat aataaaattg aaaattgtta
     8941 tagaggacaa taatgcgatt atatcggtga aaaatactta tgagaatgct gttatttatg
     9001 aaaatggaga gatacagact acaaagattc tggatacaga tgaacatgga ataggaataa
     9061 aaaatatagc tgaaacaata aggaagtacg ggggctctta tgtgattcaa aacgatgaac
     9121 gagagtttta tttttccatt atgattcctc tagtgaaaag tgatttctga gaacaaatca
     9181 cttttttgtc gttttctgca aaataagtac actttctgca atagaccttg ttaagaaatt
     9241 gtgtattgtt atacttacag tagaaggagg cgttgatatg attgagaaga tggcaatggg
     9301 gttggttgac caaatggctg aggaaaaaat gattgacaag gaagcggaag aatattatgt
     9361 ctatacgctt gtttcgttaa tggaaaaatt tataaccatt ggaactattt tgctaataag
     9421 tgtactgatt gagaaattag ttccaacagc attctttttg ttattctttt tgtcattaag
     9481 aaaaagaaca ggcggatatc atatgaatac cttttttcaa tgttatttgg gtacagtggt
     9541 tacttatatg cttgtcttag gtttatgtat ggttctggtt gactatccgc agctggtttt
     9601 tggattatta ttagttgcaa tttgcatagt tgaagttata gggactgtta atcatcccaa
     9661 catacatatg gatgcggtag aactgtcaga atcaaagagg gcggcaagaa ttttgtgtgc
     9721 agttgaagtg tgtgttattt acacttttac tttgctcgga gccgatatga tgtatgtttg
     9781 ccatatggca gttgctgtta tattatgtgc ggttctgttg ctgatagcta aaatattaaa
     9841 acaggaggta aagagaaatg aagaaaatta acaaaaaggt attgaaggtt gtggagaggg
     9901 tgataagaaa tgagattaag agagccagtg gtgatcctcc gttttgtttg gggatatttc
     9961 atcaaccgaa aagaccggta gaacataaat gtaatagaga aaataaataa agaaataaat
    10021 ggtagtatat ttcttcacag actccttaaa tcctataatt tcaagctttt gcgatacttt
    10081 gttgttcata tcattattca cccaccaggt gaagaaaata tatggtaaaa tagacgtaac
    10141 aaaacctata gattggagtc ttttaccatg aataacaacc accgaatcac actgagcacc
    10201 aataagaaca ttattgttga gtttacaaat gatacaataa atcgttctga ataaagtgtt
    10261 tttcaggaaa catccaattt aggaattttg attaagagag agataataaa atgaaaatat
    10321 gttatatagt tgtttcagct tttttgatta ttttctatcc aagacaatta acacatctta
    10381 tgtgctttgg gagacatcgt gataagaata ttgtcaaaag caaagctgct tattggggaa
    10441 tatatttgtt ttggacaatt atttttttga ttggttgtct gatgatgggt tcagcgatga
    10501 aagtaaattc tacaatggat aaattagtgt attatttcat tttaggaagt gataataggg
    10561 attgtgttga attgggaagt gaagagaatg atgaggcata tatttctaca tattatacac
    10621 gaaaggaaat caatgagagc tttttatttg aggttgtcca aaaacatgaa tatgcatatg
    10681 agatgtgtca attacaggag ttgataatta agaaacagga tgaaagatgg atactttatt
    10741 tgaatgatga ggtgatggga tatgtagaag taaaaaaagg ttttttaatt aaggagtttt
    10801 gttttgtgtg ggataggcaa aaaatagacc aaaggaggca gttatatgag taaaaaaatg
    10861 tgcaagagga tattttcagt aattttatca ttaggtcttg ttatggttca atccatgaat
    10921 gttaatgcag caggtaatga aattggtaaa tattcagtat tcgtttagtg gcagatatgc
    10981 ggtgcggaca ggcatctatt tgggatttta aaaaatagca aaaatctctg gacactgcaa
    11041 caaacaggag cctcgcagga acactgctgt aaaatccgct tagtatgagc gtattttgca
    11101 gcaagtgctc ctgcgaggct ttgtcattta atccaataaa cttaaaacgc tttatttctt
    11161 cttccacgca agaagcctct caatatgcag cggtttcccc tgaacagcct gcaccttcaa
    11221 tctgttttcc tcactgaaac caaccagaat atcatgatta gcctcagcca gataatcgat
    11281 gataccatcg atatcagact tcgtgttctt cggacaatga atatacagat gcttatttgc
    11341 ggaaatatgc agtgtatatg agatgctgaa atgataccac agaatcttgt gcagggtaga
    11401 gtatttgtaa atccataaaa tctctttgat aggcacgatg gcattgccat aaggcgaggt
    11461 catgataaaa tagtgctctg tgataaacat gtcctcggtg gcaagctgtg gcagtgtcgc
    11521 aagctcctcc tcagcctcgg caagcagttt gtgcggattg ccaaatacaa caagattctg
    11581 acatgccggt gccaaaacag gaaacctgat gcataggatg tagaatatca ggctgataac
    11641 agcatagatg agagtgccaa aataaaaaac aaacataaaa atagtagttt tcaaatggta
    11701 ctcaggctca ttaagatagt agcctgttat ggtatcggag agtcccttgg aatcccaact
    11761 cagatcctta gacagtttat ttacaaactg tgtgtaggtg ccctttccct ttacgatttt
    11821 accgaccacc gtgagtttgt cgatagaggg cagaccctcc tcacaggtgg atggtgcaag
    11881 cagtacaata gagcagtgct tatcacgcat gcagtagtag taatagccct tgatatcgtt
    11941 gccgtccttc atggtgtagc cggtaaagta aagcttttta agggtggttt ttacatatct
    12001 gtccgaatcc ttgtatgcag cttcaaagct gacagaatcg tcaatgtgta tgggcgataa
    12061 aatatctccg agtgaaaatg caaaccatag cacggtaagc agaatgatgt atacaatcgg
    12121 agagaaaaga cgccttttgt aaaatgcttt gatgtttttt gttatgtagt gttcgtaatt
    12181 atcaatcata tgcttagtat aatggttttt gtgccttata tcaaccttga ttttgagaca
    12241 tttaattgtt attatatagt tactgtaaat agaaacacga aatgaggtaa ttatggaagc
    12301 atacacgagt tttgcccggg tgtatgacat gttcatggac aatgtgccat atgagaagtg
    12361 gagcagatat attgtcgaaa aactgcgtgc aaatggcata gacagtggat atgtcgtgga
    12421 cttaggctgt ggtacgggaa agcttaccac gcttcttgca gatgcaggct atgatatgat
    12481 aggcattgac aattcttttg acatgcttga tatggcgctt gagagagagg atgacagaat
    12541 cctttatctg atgcaggata tgagagagtt tgaaccggga gaaaaggtga gtgccgtcgt
    12601 aagcgcatgt gacagcatca attacattct tgagcctgag gatctgcagg cagttttttt
    12661 ctgcgtgagc gaaagtctca aagagggtgg catttttata tttgatatca atactccata
    12721 caaatatgag gtgctcatgg ctgataatac catagctgaa aaccgtgatg agggcagctt
    12781 tatatgggac aattattatg atgccgatga gaaaataaac gagtatgacc tgacactttt
    12841 tataaaggag cagtcagagg atgaggatga catctacaag aagtttgagg aaactcattt
    12901 ccagagatgc tatgagattt cagagcttaa ggagcttctt gagcagtcgg gacttgtgtt
    12961 tgatgcggtg tatgatgcgt acacagacaa tcaggtgaaa tgtgacagtg agaaggtcac
    13021 tttaattgca cataaagcat agaattagat aatgagaggt aaattatgtc agattatata
    13081 gtaagagcaa cagcggcgga tgccaatatc agagcatttg ctgtaacatc aaaggagatg
    13141 gtggagaacg ccagagagga tcacatgaca acacctgtca tgacggcggc acttggcaga
    13201 ctcctttctg cgggagccat gatgggagct atgatgaagg gcgataagga tatcataact
    13261 cttcagatac agtgcagcgg acctgcaaag ggacttaccg tcacagcaga ttcgcacggc
    13321 aatgtaaagg gctttgccat gaatccacag gttgagctgc cactcaatgc ggcaggcaag
    13381 ctcgatgtgg gaggagcgct tgatcttggt atacttacag tcataaagga tatgggctta
    13441 aaggagccgt attcaggtca gtgtgagctt aaaacaggtg agatagctga ggatctgact
    13501 tattattttg ccacatctga gcagattccg tcggcggttg gtcttggcgt gctggtggat
    13561 aaggaccaga gcgtgaagca gtccggtgga tttatcatcc agcttatgcc gtttacaccg
    13621 gaggatgttg tggacaggct tgaaaagaaa atcacagaga ttgattctgt gacacagatg
    13681 cttgacaggg ggctgactcc ggagcagata cttgaggaaa ttttagggga tttcgggctt
    13741 gaaatcacag atacgacaga gacacgcttc cactgtgact gttcaaagga gcgtgtgagc
    13801 agagcacttt ccacacttag caaaaaggat cttgattcca ttatcgcaga tggcgagagc
    13861 attgaggtaa agtgccagtt ctgtaataag gcatatgagt ttacggtgga tgagttgaag
    13921 gagatgcgct aattgaagga cggatatata aaggtcgctg cagcgacacc aaaggtaaag
    13981 gtagctgata ctgtatacaa cggacagctt attaaagctc ttatgaagga gtgcactgac
    14041 aacggggcaa aggtggttgt tttcccggag ctttgcatta ccggatacac ctgtcaggat
    14101 cttttctggc aggataagct catagctgca gcagaggatg agcttatagg gatagcagat
    14161 tacagcagga gccttgacgg catatttttc atagggcttc catatgagat aaacggcatg
    14221 ctctataata tggcggcagt tgtatcgcgc ggagaggtgc ttgccatggt gccaaagaca
    14281 tttctgccaa actataatga gttttatgag gcaaggcatt ttgcatcggg agaaaactta
    14341 agcacatatg tcacactgaa aaatggacag caggtgtctg tagatactga ttttattttt
    14401 agctgcaagc agctgccaaa gcttaagata gcggtggagc tttgtgagga tctttggact
    14461 ccgaacccgc cgagcatcag acacgcgatg tctggtgcca ctgtgattgt aaatctgtct
    14521 gcatcagatg aggtgacagg caaggcaata tacaggagag agcttgtgag cggacagtct
    14581 gccagattaa tctgtggata tatttatgcg tcagcgggag acggtgagtc cacacaggat
    14641 gtggtctact caggacacaa tctcatctgt gaaaacggaa atgtgcttgc cgagtcaggg
    14701 cgctttacaa atgagactat atacagcgag tttgatgtgg aaagaataga gactgagagg
    14761 cgcaggatga caacctttgt tgtcgaggat gaccacagat gggctgagtt tgaccttgag
    14821 gtaaaggata ccactcttag ccgctatgtg aatccggctc cgtttgttcc ggcggacaag
    14881 acagacaggg acagacgctg tgatgagatt ctcatgattc aggctatggg acttaaaaag
    14941 cgattagagc ataccaactg taagacagca gttatcggta tttcaggagg acttgactcc
    15001 acattggcac tgcttgtcac ggtaagggca tttgatcttt tgggaaagga tcacaaggat
    15061 atagcggcag ttactatgcc gggctttgga acaacagacc gcacatatga caatgcggta
    15121 aacctaataa aatgccttgg tgctacattt atcgaggtgg atataaagga tgctgtaaat
    15181 atacatttca gggatatcgg acaggatccg tctgtgcatg atgtcaccta cgagaatgga
    15241 caggcacgcg agcgcacaca gatacttatg gatatcgcaa acaaggaaaa cggaatggtc
    15301 ataggtacag gagatttgtc agagctggca ctcggctggg ctacctacaa cggagaccat
    15361 atgtccatgt atgctgtaaa tgcatcggtt ccaaagactc tggtgcgcca tctggtaaaa
    15421 tactatgcag atacctgcgg cagcgatttg ctggaaagta cacttcttga tgtgcttgat
    15481 acacctgttt ctcctgagct tttaccacct gaaaacggta agatttcaca gaagacagag
    15541 gatcttgtgg gcccttatga gctgcatgac ttcttccttt acaatatgct gcgctgcggc
    15601 tatgctcctg ccaaggttta ccgccttgca aggatagcat ttgaaggaaa atatgatgat
    15661 gagtttattc tcaaatggct taagaacttc tatcgcagat ttttcgcaca gcagttcaag
    15721 cgctcatgtc tgccggatgg accaaaggta ggaacagtgg cggtctcacc gagaggagac
    15781 ctaaggatgc cttctgatgc gtgtggacgt atctggatgg atgaggttga taagctgtaa
    15841 tagtaagagg agaacaatgg gaaagacaca taagaaaact catagaaggc agggaagcat
    15901 aaaacgtgca aggcaccgcg acaggcgcat gaaaataggc gcaatagttc tttgtgcagc
    15961 gataatcata acaacatttc tggcgtgtgg catgcagctt ttagttcccg tagctgacgc
    16021 ggtggtaggt gctgataata agacgcaatc aagagatgtt gatgtgcaga agaataataa
    16081 ttcacttacc gcatctaaaa tggattcaga aaaaaagcaa aacagctcag aggctgatgt
    16141 aaactctgcg gagcaagaca gtgagcctga caaggaaacg aagcttgatg agatacttca
    16201 cagtgcaaag tatccgggac agctaaagga gcttgccaag aaaaatgatg aggcaattga
    16261 cttcatatat gagtatccta aggagcattc gatagagcat gatattgatc tgactgcaga
    16321 ggcttcgcag gatacagtac ctcttttgca gcagtgggat aagagatggg gctatgaaaa
    16381 gtacagtggc aattattttg cggcgagtgg ctgcggtccg actgcacttt cgatggttgt
    16441 attatatctg acacatgatg cacaggcatc ccctcttgcg gtggcagagt atgcaaagga
    16501 ggccggctac agtgtggatg gctccggaag tgcatggaat cttataagca agggctgcag
    16561 gcactacggg gtaaatgcaa agactataaa ggtggatgag gatacattta aagaaaggct
    16621 tgatgagggc aatctgatag tcgtaaatgt cggtccggga gatttcacag aaaagggaca
    16681 ttttatggtg atcacaggct atgatgatga gggctttact ataaatgatc caaacagtat
    16741 cataaagagc aatacccact ggcagtttga gaggctgggt tcgcagatca gggctgcatg
    16801 gaggatgttt gtgtagataa tagcagcaat acatgcattt atgctgatgt ttgtgatgca
    16861 tatggaaaaa ttaaaaataa gaaataaaaa acctgctgtg tcatgcttgt ctgacacagc
    16921 aggtttttaa taacaaacag taaagtatgg tatgcagatt atagcaattg aataccatgc
    16981 tcctcacatg ccttaattgt ctcctcaggc cacagtgagc tctgtacctc accgatatga
    17041 gcctttctga ggaagaacat acagattcgt gactgtccga ttccgcctcc gatagtgtac
    17101 ggaagctcct tgttgaggat agccttctgg aatggaagct tagcacgctc aggacatccg
    17161 gccttgtcaa gctgttcctt tagggctttt tcatctacac ggatacccat tgatgaaagc
    17221 tcaagtgcga tatcaagaac aggatagtac acgatgatat cagcgtttaa agcccagtcg
    17281 tcatagtcag gggcacgtcc gtcgtgaggc tctccgtttg caagcttgtc accaatctgc
    17341 attacacaga ttgcaccctt tgcctttgca aaataatact cgcgctcctt tggagtattg
    17401 tccgggaaca tttcctcaag ctctgatgtg gtgataaagg tgatatcctt tggcagaatt
    17461 aaatctatgt agtcgtactg tatagccatg tactgctcgg tcttgcgcag gcatttgtat
    17521 actgtcttta ctgtttcctt aaggaagtct aagtttctgt cctccttgcg gatgatcttt
    17581 tcccagtccc actggtcaac aaatatagag tggatattgt cagtctcctc atcacgtctt
    17641 atggcattca tatctgtgta gatgccctcg ccgagagaga agccgtattt ctttaatgca
    17701 tatctcttcc acttggcaag agagtgaacg acctctgcct ccttgtcacc ctgctcaagg
    17761 atgccgaagg taacaggtct ttcatatccg tttaagttat cgtttaagcc tgtggtagga
    17821 tcaacgaaaa gcggtgctga aacacgtgtc agggaaagac gctgtgcgag catgccctgg
    17881 aagaaatcct taacagtctt gatggcaagc tgtgtatcgt gaagattcag tgccgaagaa
    17941 tagttctttg gtattgttaa tttgctcatt ttcgattaaa cctcgttgta ttattaattt
    18001 ttaaataaaa ttcctttaac ctgattatta tatcacaatt tttctagaaa gatagtccat
    18061 aatatgataa aattagatag tttaaagaga aacaatatcg ttttacctta tttttacgtg
    18121 tttaaggtgt taatgaaagg tagtagattt atatgagaaa aagagatatg acctttgctt
    18181 cggcggtgct tgaggcaata gatgctattt tagctcttgc gtatataggc ttacagattt
    18241 attatggagt gtgctatcac atacaggtat ttaagtttgt ggccaatata cttgtgcttt
    18301 tgcttgtata cattgcaatc acatggctgc agcattatcc ggaaaagctc aatcacatag
    18361 cagcggagct gtgtgtgggc aatatcagaa agtattcact caggcttttg acgtttgtaa
    18421 agcttgtttt tactgcgggg cttttggtgc catgcgtgtg tgatgcgttt ggaatagcaa
    18481 tacgcgatgt atacagcctt attatgatag ggctcatcct tgtggtgacg gcatattatg
    18541 agtacaggat atttcaggaa ataaagtcat tgcggaaata atataggaga aataaaatgc
    18601 agcttagtat agaagaagtt aaaaagctgg atagtaacag ctatcagata atagatataa
    18661 gaagtgagga agaggtggcg cacggtgcca taaagggagc actcaatatt caggcagagg
    18721 aaatagagtc agatgagagg gtgccacatg ataagaagct tgtcatagtc tgcagccgtg
    18781 gtaagacgag tgtggatgtg gcagagtatc tcacagaaaa aggttttgat gcggcaagct
    18841 taaagggagg ctatataagc tggctgcttg atgccatgaa agaggatgag gtggcagagc
    18901 gcgatataaa ggcagatgtg gagcaaagca tcagaaagaa atttaagaaa tccatctggc
    18961 gcaagtttac aaaggcgata aatacctatg agcttgtaaa accgggggat aagattgcag
    19021 tgtgtatctc gggaggtaag gattccatgc tcatggcaaa gctgtttcag gagcttaagc
    19081 atcacaataa gtttgatttt gatgtgaagt ttctcgtcat ggacccgggc tacaatgagg
    19141 caaacaggca tgtcatagag gaaaactgca ggaaccttgg catccctgcc actatttttg
    19201 agtcagatat atttgatgct gtatatgata tcgaaaaatc gccatgctat ttatgtgcga
    19261 ggatgagaag aggacatctg tatgcatttg caaaggagct gggctgcaac aaaattgcgc
    19321 tcggacatca ctatgatgat gttattgaga cgatactcat gggtatgctc tacggtgcac
    19381 aggtacagac catgatgcct aagcttcaca gcacaaactt tgagggcatg gagcttatca
    19441 ggcctcttta cctggtcagg gaggacgata tcaaggcatg gcgtgattac aacggtctgc
    19501 atttcataca gtgtgcctgc aagtttacag atacctgtac cacctgcaat aatgaggaaa
    19561 accgctcaaa gcgtgttgag ataaagcagc tcatcgctaa tcttaaaaag gtgaatcctt
    19621 ttgtcgaggc aaatatattt aagagcgtgg agaatgtaaa tctggctacg gttgtagcat
    19681 ataaaaagga tggcataaag cacagcttcc tagatcacta tgatgaataa
//
