LOCUS       c00005_NZ_SILH..       20918 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_SILH01000006.1 Rhizobium leguminosarum strain SM52 map
            unlocalized plasmid pSM52_Rh21 p_SM52_Rh21, whole genome shotgun
            sequence.
ACCESSION   NZ_SILH01000006
VERSION     NZ_SILH01000006
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:45:39
            Original ID  :: NZ_SILH01000006.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 98461
            Orig. end    :: 119379
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..930
                     /locus_tag="ctg5_105"
                     /transl_table=11
                     /translation="VVKARSGKNAKGSSDVEQKIDIEAILRDRMSDFSPSEQSLAAYIL
                     DNIQILPFETGSSIAEAVGVSEMTVTRFVRGLGFENLRDLKKRLRVAVAEKDSEVDDYM
                     ARFPMREGRQQMLQESLRLELDAIVKAYALTTTDAWDEAANLLAKARTIYVVGFQASKG
                     LAMDFASRLLWARSNVIFIDNASGTFGEIINADPKQSAVVLVDTASYATRGIKLLEKLK
                     SMDMPLVIVTDKFSHWAFAYTRFVFEAHTHVKTFWDSTASLSVVLNLLIDAVAIKLGPK
                     AKANFAMMSDMGTLFGEFVGGSYLRRND"
     protocluster    1..20918
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[107616:109966]"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9156..11505
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     cand_cluster    1..20918
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20918
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="2"
                     /rules="Autoind_synth"
                     /tool="antismash"
     PFAM_domain     64..285
                     /aSDomain="HTH_6"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01418.19"
                     /description="Helix-turn-helix domain, rpiR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_105_0017"
                     /evalue="2.70E-10"
                     /label="ctg5_105"
                     /locus_tag="ctg5_105"
                     /protein_end="95"
                     /protein_start="21"
                     /score="40.2"
                     /tool="antismash"
                     /translation="IEAILRDRMSDFSPSEQSLAAYILDNIQILPFETGSSIAEAVGVS
                     EMTVTRFVRGLGFENLRDLKKRLRVAVAE"
     PFAM_domain     436..813
                     /aSDomain="SIS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01380.24"
                     /description="SIS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_105_0018"
                     /evalue="7.90E-06"
                     /label="ctg5_105"
                     /locus_tag="ctg5_105"
                     /protein_end="271"
                     /protein_start="145"
                     /score="25.8"
                     /tool="antismash"
                     /translation="LLAKARTIYVVGFQASKGLAMDFASRLLWARSNVIFIDNASGTFG
                     EIINADPKQSAVVLVDTASYATRGIKLLEKLKSMDMPLVIVTDKFSHWAFAYTRFVFEA
                     HTHVKTFWDSTASLSVVLNLLI"
     CDS             960..2147
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 72.9; E-value: 4.4e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_106"
                     /transl_table=11
                     /translation="MTSISPFRDPTAPGNPLFPRQDWDRAPWNRWTFQHVRDLLPTTKV
                     WRGAGPASLLLADLRDIDVIPFVAEGEAHTIGSFLETSYADGFLVLHGGKIVAEHYLNG
                     MTSHTQHLSQSVAKSVVGTVAGILIGRGVVDPAASLTHYLPELEATAYRGATVQHVLDM
                     TSGVVFDETYTAPDSHMAQLDVASGWKNGQNPNWHKNIWDLVLSLKDLECPHGTSFRYR
                     SIETDVLSFVLERAAATPLAELVSRELWAPMGAEEDAYFTVDAAGYALGDGGFNATLRD
                     YARFALLHLRGGEINGRRIVPSEWIAGTRFGADPKLFGGIYQEVLPAGAYHNQFWIEDT
                     ARGVYMARGVFGQLIYIDPVADFAAVVLSSWPEFVSTTRTRTALAAVTAVREALL"
     PFAM_domain     1221..2108
                     /aSDomain="Beta-lactamase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00144.26"
                     /description="Beta-lactamase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_106_0019"
                     /evalue="1.00E-31"
                     /label="ctg5_106"
                     /locus_tag="ctg5_106"
                     /protein_end="383"
                     /protein_start="87"
                     /score="110.6"
                     /tool="antismash"
                     /translation="FLVLHGGKIVAEHYLNGMTSHTQHLSQSVAKSVVGTVAGILIGRG
                     VVDPAASLTHYLPELEATAYRGATVQHVLDMTSGVVFDETYTAPDSHMAQLDVASGWKN
                     GQNPNWHKNIWDLVLSLKDLECPHGTSFRYRSIETDVLSFVLERAAATPLAELVSRELW
                     APMGAEEDAYFTVDAAGYALGDGGFNATLRDYARFALLHLRGGEINGRRIVPSEWIAGT
                     RFGADPKLFGGIYQEVLPAGAYHNQFWIEDTARGVYMARGVFGQLIYIDPVADFAAVVL
                     SSWPEFVSTTRTRTA"
     CDS             2299..2715
                     /locus_tag="ctg5_107"
                     /transl_table=11
                     /translation="MARERRAKLRKLARFSLLRQSVIGRILHGWSPQQIAGRMRPERHP
                     ISIIMRRSITSPISRTVTPSNCGDTCRSIVQTPARYARRRHVRVFSREVNILNPDVVAA
                     RKQFGYRECVLMQFRKKFGKANVTSLVERVIRFR"
     CDS             complement(2959..4863)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 254.6; E-value:
                     3.2e-77)"
                     /gene_kind="transport"
                     /locus_tag="ctg5_108"
                     /transl_table=11
                     /translation="VTTMGKSTESNRLEQSMFGWFEQRLNPFPSEEPVAPPKGLFAFCW
                     HYSKPAAPWLGLIAVLTALIAIGEVALFQFLGDIVGWLTNADRATFLEREGHKLFWMAA
                     LVLVGLPLTAGLESFIMHQMMLGNYQMSARWQMHRFLLRHSMSFFANEAAGCVGTKVMQ
                     TSIAVRETVIRILDVFVYVVTYFLTMIVVIAAADWWLMIPILVWLAVYISIVAYFVPRL
                     RKIAAAQADARSMMTGRVVDSYTNIATVKLFSHAGREEVYAKESMDEFLQIVHKQLRKV
                     ALFHICVYLNNCVALFVISGQSIWFWLSGAISVGAIAIAIGLAMRFNFMSQWIMREVTA
                     LFENIGTVYDGMEMMSKQHDIVDKPGAPTLTAKKGAIHYDRIRFHYGKSKGVIDNLSLD
                     IKAGEKVGLVGRSGAGKTTLMKLLLRFYDLEAGRITIDGQDIAGVSQESLRSLIGVVTQ
                     DTSLLHRSIRDNIAYGRPDATDAEVIEAAKRANAWEFIEGLVDLQGREGLNAQVGERGV
                     KLSGGQRQRIAIARIFLKDAPILVLDEATSALDSEVEAAIQKNLFTLMEGKTVIAIAHR
                     LSTLTEMDRLIVLDKGRIIEAGSHSELIAGGGIYADLWNRQSGGSLSNHPEEAEVAAE"
     PFAM_domain     complement(3223..3684)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_108_0021"
                     /evalue="3.20E-34"
                     /label="ctg5_108"
                     /locus_tag="ctg5_108"
                     /protein_end="547"
                     /protein_start="393"
                     /score="118.5"
                     /tool="antismash"
                     /translation="DNLSLDIKAGEKVGLVGRSGAGKTTLMKLLLRFYDLEAGRITIDG
                     QDIAGVSQESLRSLIGVVTQDTSLLHRSIRDNIAYGRPDATDAEVIEAAKRANAWEFIE
                     GLVDLQGREGLNAQVGERGVKLSGGQRQRIAIARIFLKDAPILVLDEATS"
     PFAM_domain     complement(3889..4698)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_108_0020"
                     /evalue="1.70E-14"
                     /label="ctg5_108"
                     /locus_tag="ctg5_108"
                     /protein_end="325"
                     /protein_start="55"
                     /score="54.3"
                     /tool="antismash"
                     /translation="GLIAVLTALIAIGEVALFQFLGDIVGWLTNADRATFLEREGHKLF
                     WMAALVLVGLPLTAGLESFIMHQMMLGNYQMSARWQMHRFLLRHSMSFFANEAAGCVGT
                     KVMQTSIAVRETVIRILDVFVYVVTYFLTMIVVIAAADWWLMIPILVWLAVYISIVAYF
                     VPRLRKIAAAQADARSMMTGRVVDSYTNIATVKLFSHAGREEVYAKESMDEFLQIVHKQ
                     LRKVALFHICVYLNNCVALFVISGQSIWFWLSGAISVGAIAIAIGLAM"
     CDS             complement(4991..6250)
                     /locus_tag="ctg5_109"
                     /transl_table=11
                     /translation="MKNPMLKIALERVIEAAEHLDLHPGFLEKLKKPLETTQARLSILM
                     DDGSTKCFIGWRCRYDDSLGPTKGGIRWDQMVNADEVETLGLLMTLKNALMGLPFGGGK
                     GGVKVDPRGLSNTEQERLGRAYIRAFAAVIGPDRDIPAPDVGTNEKIMAWMMDEYSTIV
                     GKRTPAVITGKPVALGGSRGRDDATARGAYNIMRYKADTLKLEHGTRVAIQGFGNAGKH
                     IAKLLAADGCKINAVSDSKGAVHAPAGLDISKLLAAKRHGSVTSMAGSAGVSEISGDEL
                     VSVECDILILAAVENMVHEGNAASIKARVIVELANGPVTPEADEILEAMNVEIIPDILV
                     NAGGVTVSYLEWVQNRQGERWTLEQVHAWLKTKMESEADAVLAYARDKNITLRTAAYVL
                     ALSRIAAAMEALGTDKFFQA"
     PFAM_domain     complement(5015..5716)
                     /aSDomain="ELFV_dehydrog"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00208.23"
                     /description="Glutamate/Leucine/Phenylalanine/Valine
                     dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_109_0023"
                     /evalue="8.60E-63"
                     /label="ctg5_109"
                     /locus_tag="ctg5_109"
                     /protein_end="412"
                     /protein_start="178"
                     /score="212.4"
                     /tool="antismash"
                     /translation="GGSRGRDDATARGAYNIMRYKADTLKLEHGTRVAIQGFGNAGKHI
                     AKLLAADGCKINAVSDSKGAVHAPAGLDISKLLAAKRHGSVTSMAGSAGVSEISGDELV
                     SVECDILILAAVENMVHEGNAASIKARVIVELANGPVTPEADEILEAMNVEIIPDILVN
                     AGGVTVSYLEWVQNRQGERWTLEQVHAWLKTKMESEADAVLAYARDKNITLRTAAYVLA
                     LSRIAAAMEALG"
     PFAM_domain     complement(5771..6145)
                     /aSDomain="ELFV_dehydrog_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02812.20"
                     /description="Glu/Leu/Phe/Val dehydrogenase, dimerisation
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_109_0022"
                     /evalue="3.40E-46"
                     /label="ctg5_109"
                     /locus_tag="ctg5_109"
                     /protein_end="160"
                     /protein_start="35"
                     /score="156.3"
                     /tool="antismash"
                     /translation="TTQARLSILMDDGSTKCFIGWRCRYDDSLGPTKGGIRWDQMVNAD
                     EVETLGLLMTLKNALMGLPFGGGKGGVKVDPRGLSNTEQERLGRAYIRAFAAVIGPDRD
                     IPAPDVGTNEKIMAWMMDEYS"
     CDS             complement(6434..6706)
                     /locus_tag="ctg5_110"
                     /transl_table=11
                     /translation="MAALRQIAFYGKGGIGKSTTSQNTLAALVELGRKILIGCQPLVDF
                     ARLILCKRRIERVKNWKFGKADYAKWGRLLGQRHSRLKGRPKLGP"
     PFAM_domain     complement(6539..6694)
                     /aSDomain="Fer4_NifH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00142.20"
                     /description="4Fe-4S iron sulfur cluster binding proteins,
                     NifH/frxC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_110_0024"
                     /evalue="7.30E-16"
                     /label="ctg5_110"
                     /locus_tag="ctg5_110"
                     /protein_end="56"
                     /protein_start="4"
                     /score="58.5"
                     /tool="antismash"
                     /translation="RQIAFYGKGGIGKSTTSQNTLAALVELGRKILIGCQPLVDFARLI
                     LCKRRIE"
     CDS             7412..7945
                     /locus_tag="ctg5_111"
                     /transl_table=11
                     /translation="MRIDSISIGKNPPDDVNVIVEVPVGGQPIEYKMNKESGALVVERF
                     LSTPMAYPGNYGFVPHTMSEDGDSIDVLIVDTRPLVERCVINVRPIGVLVMEENGRKDE
                     KIIAVPMANLTRLYDKVRDYTDLPEISLKQIEYFFSYYKDLKPGEWVKIAGWKDVNVAK
                     KMILEAAGRYNSKT"
     PFAM_domain     7463..7930
                     /aSDomain="Pyrophosphatase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00719.21"
                     /description="Inorganic pyrophosphatase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_111_0025"
                     /evalue="9.70E-45"
                     /label="ctg5_111"
                     /locus_tag="ctg5_111"
                     /protein_end="173"
                     /protein_start="17"
                     /score="152.3"
                     /tool="antismash"
                     /translation="VIVEVPVGGQPIEYKMNKESGALVVERFLSTPMAYPGNYGFVPHT
                     MSEDGDSIDVLIVDTRPLVERCVINVRPIGVLVMEENGRKDEKIIAVPMANLTRLYDKV
                     RDYTDLPEISLKQIEYFFSYYKDLKPGEWVKIAGWKDVNVAKKMILEAAGRY"
     CDS             8150..8737
                     /locus_tag="ctg5_112"
                     /transl_table=11
                     /translation="MKRTYSQIDMEERRKIARWRTAGISVDVIAEKLHRHRSTIFRELR
                     RNTFEDREMPDLNGYYCVMANDMARERRAKLRKLARFSQLRQSVIERIMHGWSPQQIAG
                     RLQLERHPISVSHETIYKFAYSSDGHAIKLWRHLPEHRARRRPRHARRRHGRRFTRMST
                     FSTGQTPSPSANSSGIGNAISSSFARSSERPT"
     PFAM_domain     8162..8290
                     /aSDomain="HTH_38"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13936.8"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_112_0026"
                     /evalue="2.10E-13"
                     /label="ctg5_112"
                     /locus_tag="ctg5_112"
                     /protein_end="47"
                     /protein_start="4"
                     /score="49.9"
                     /tool="antismash"
                     /translation="YSQIDMEERRKIARWRTAGISVDVIAEKLHRHRSTIFRELRRN"
     CDS             8809..9159
                     /locus_tag="ctg5_113"
                     /transl_table=11
                     /translation="MDGLIQVLQSLPHLARRSITFDRGTEFTDWPYLQASIGAQTWFCD
                     PQSPWQKGTVENTNRRARKWLSREVDPLSLSDRDLTEICNRLNATPRKCLGYKTPAEVF
                     RQKLLAQIRRTG"
     CDS             complement(9156..9851)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_114"
                     /sec_met_domain="Autoind_synth (E-value: 3.3e-23, bitscore:
                     76.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRLYVGRHESRGQAMEKIWRFRHEQFVERLGWEALRRNDGLEID
                     QFDHDRALHLALFFEDTVVGYTRLLPTTEPHLLSDVYPQIMKGQAWPRSPEIFEWTRCI
                     VAEGQILINGVSASHVLMTGVMEFCLVAGITSVIVETHPKLVQLLVSTGWNVTELGPPS
                     LLNGVLIVPIQAKPSMSGLRKHHQLYSIQGSTLLLEPEVRNPLKPEATLHHLHYCEFMA
                     KRDLEADRG"
     PFAM_domain     complement(9363..9812)
                     /aSDomain="Autoind_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00765.19"
                     /description="Autoinducer synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_114_0027"
                     /evalue="5.90E-21"
                     /label="ctg5_114"
                     /locus_tag="ctg5_114"
                     /protein_end="163"
                     /protein_start="13"
                     /score="74.9"
                     /tool="antismash"
                     /translation="QAMEKIWRFRHEQFVERLGWEALRRNDGLEIDQFDHDRALHLALF
                     FEDTVVGYTRLLPTTEPHLLSDVYPQIMKGQAWPRSPEIFEWTRCIVAEGQILINGVSA
                     SHVLMTGVMEFCLVAGITSVIVETHPKLVQLLVSTGWNVTELGPPS"
     CDS             complement(10115..10858)
                     /gene_functions="regulatory (smcogs)
                     SMCOG1197:autoinducer-binding transcriptional regulator,
                     (Score: 152.8; E-value: 1.6e-46)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg5_115"
                     /transl_table=11
                     /translation="VDSEALATANVMFDFISDAALAKSSEDILKSLNRTACHFGFSCFA
                     MSGIPLPTERIDPYFLLNAWPYEWFERYSTGNYVHADPVIHLSKMQDGAFVWSEALQGQ
                     ELGRHARRIMMEAREFKMKDGYSVPLHTADGFQAIITFGAEKVDLSRAARGALHIISIY
                     AHNTVRSLLTKNVSSQDRRLLRITAREREIIQWCAAGKTAVEIAAILGRSHRTIQNEIL
                     NVQRKLDVVNSAQMIAESFRYGILR"
     PFAM_domain     complement(10148..10300)
                     /aSDomain="GerE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00196.21"
                     /description="Bacterial regulatory proteins, luxR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_115_0029"
                     /evalue="3.00E-12"
                     /label="ctg5_115"
                     /locus_tag="ctg5_115"
                     /protein_end="237"
                     /protein_start="186"
                     /score="46.0"
                     /tool="antismash"
                     /translation="TAREREIIQWCAAGKTAVEIAAILGRSHRTIQNEILNVQRKLDVV
                     NSAQMI"
     PFAM_domain     complement(10358..10786)
                     /aSDomain="Autoind_bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03472.17"
                     /description="Autoinducer binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_115_0028"
                     /evalue="7.20E-30"
                     /label="ctg5_115"
                     /locus_tag="ctg5_115"
                     /protein_end="167"
                     /protein_start="24"
                     /score="103.5"
                     /tool="antismash"
                     /translation="SEDILKSLNRTACHFGFSCFAMSGIPLPTERIDPYFLLNAWPYEW
                     FERYSTGNYVHADPVIHLSKMQDGAFVWSEALQGQELGRHARRIMMEAREFKMKDGYSV
                     PLHTADGFQAIITFGAEKVDLSRAARGALHIISIYAHNT"
     CDS             complement(11011..11505)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_116"
                     /sec_met_domain="Autoind_synth (E-value: 2.1e-16, bitscore:
                     54.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRLYVGRHESRGQAMEKIWRFRHEQFVERLGWEALCRNDGLEID
                     QFDHDRALHLALFFEDTVVGYTRLLPTTEPHLLSDVYPQIMKGQAWPRSPEIVPIQAKP
                     SMSGLRKHHQLYSIQGNTLLLEPEARNPLKPDATLHQVKPALTSGPGHLQVHCHKQRRS
                     C"
     PFAM_domain     complement(11221..11466)
                     /aSDomain="Autoind_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00765.19"
                     /description="Autoinducer synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_116_0030"
                     /evalue="4.20E-14"
                     /label="ctg5_116"
                     /locus_tag="ctg5_116"
                     /protein_end="95"
                     /protein_start="13"
                     /score="52.6"
                     /tool="antismash"
                     /translation="QAMEKIWRFRHEQFVERLGWEALCRNDGLEIDQFDHDRALHLALF
                     FEDTVVGYTRLLPTTEPHLLSDVYPQIMKGQAWPRSP"
     CDS             11742..12260
                     /locus_tag="ctg5_117"
                     /transl_table=11
                     /translation="MRLFVNFFQPSFKLLEKRRDGTLVKKRYASPATPHQRLKTDPRTS
                     TEVRNRLLHMSEQLDSVKLLRGIRAGQQRLVDIAHQGAPSTDAPDIESFLQSLRVAWTD
                     GKVRPTAKAKPKLKGERRRPDPLVSVTEDLRAWFQEEPWRTGRELLERLQSIYPGEYLD
                     GLIRTCSGE"
     CDS             complement(12614..13318)
                     /locus_tag="ctg5_118"
                     /transl_table=11
                     /translation="MLIAIEGIDGAGKTHIARKLAHNLRDGGYLARYLNKSDIEFGDAF
                     TDSRLRLLKEIIWPEQGEPKIDLLGTHFYLFLLASWFSAVGQMLRREPRFGNLITVMDG
                     SQFRVVAKAHCRAKIDRAQLLDYFDRAAEPDLVVLLEIEPHVSWHRRTVFKETEMGRWD
                     GYRGDPRDAYCAYQTKIQNVLQEMACERGWLVVPQNEDTRDTDVVDCILQHIAAQHDVE
                     EYHLARKATPCE"
     CDS             complement(13411..14847)
                     /locus_tag="ctg5_119"
                     /transl_table=11
                     /translation="MAKLLQLAIKGGRRLARRSLYEEQTVERVAIIGGGPAGLAVGQAL
                     AKQRIKFLLFEAGRTLAERKHDVADHLGSGIGGAGLFSDGKFSFFPSGTHLYTLEGRCR
                     LEDAYGAIERQLAEVGIPAPPFDPDTETSFLGTGQPMICKDYPSTYGSLAQRNALIAAM
                     MHEFSNLILANTRVEMIIPSPQGYLVQSRGADGDLREEFFTHLAIATGRFGPQALRSMM
                     TAPIAMTDLRYEFGIRIEHPNGVGFLNAVKRPDVKYILDAACTEVRTFCTCRDGEVWMI
                     PYGGTAALSGRSDGPPTGYSNFGLLARFGGNNLDRGRQIWADLQQRLGSDTTATWQPLT
                     EFLDRPSISQALEFGKADRPWFPRQKFSRGDVAALLHPELYRILAESARMLITQFPDMA
                     TPETVCIFPSVEGVGAFPTVDAALQNHSGRIWYCGDVVGRFRGLVPALVSGHYVGASIA
                     ACLRETAAEELHDVQTIAAQ"
     PFAM_domain     complement(14665..14757)
                     /aSDomain="NAD_binding_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13450.8"
                     /description="NAD(P)-binding Rossmann-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_119_0031"
                     /evalue="1.30E-04"
                     /label="ctg5_119"
                     /locus_tag="ctg5_119"
                     /protein_end="61"
                     /protein_start="30"
                     /score="22.2"
                     /tool="antismash"
                     /translation="IIGGGPAGLAVGQALAKQRIKFLLFEAGRTL"
     CDS             complement(14889..16004)
                     /locus_tag="ctg5_120"
                     /transl_table=11
                     /translation="MVQLSREETFLLLTCRPDLTPSDDVRLQRIVDSDLDWSFVLWRAE
                     SYQTLPLCGFHLNRLALLPRTPEWVVHYIHMWSQLSKARSEVQFRRLGELLGHFRACDL
                     EHYLFKGPLLAALLYSDPALRPMQDLDIMVRKADVWRVQKELYRLGYQHGVFNPADGVF
                     THMFRKITHQTLEHKYALHSVTMVEEIRPKFDTTLIAPEWRTRQIKSFVQDDGSVRMPV
                     FVDIHFSLGAGMEEVDVWRGAGPRRLLGREVHCQSLTSVLWFSAARIYFEAYQHGTLKL
                     QMLGDIDALLRLHAEDIDWPELLAVAGKYGFSAAIFYVLEQVRRLFDAPVPLKVLALLM
                     PDQQGRPDEADFGDIVPKLLSRTVISDLQLA"
     PFAM_domain     complement(15024..15905)
                     /aSDomain="NTP_transf_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14907.8"
                     /description="Uncharacterised nucleotidyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_120_0032"
                     /evalue="1.00E-32"
                     /label="ctg5_120"
                     /locus_tag="ctg5_120"
                     /protein_end="327"
                     /protein_start="33"
                     /score="113.8"
                     /tool="antismash"
                     /translation="DLDWSFVLWRAESYQTLPLCGFHLNRLALLPRTPEWVVHYIHMWS
                     QLSKARSEVQFRRLGELLGHFRACDLEHYLFKGPLLAALLYSDPALRPMQDLDIMVRKA
                     DVWRVQKELYRLGYQHGVFNPADGVFTHMFRKITHQTLEHKYALHSVTMVEEIRPKFDT
                     TLIAPEWRTRQIKSFVQDDGSVRMPVFVDIHFSLGAGMEEVDVWRGAGPRRLLGREVHC
                     QSLTSVLWFSAARIYFEAYQHGTLKLQMLGDIDALLRLHAEDIDWPELLAVAGKYGFSA
                     AIFYVLEQVRRLF"
     CDS             complement(16026..16442)
                     /locus_tag="ctg5_121"
                     /transl_table=11
                     /translation="MSDSLLFGYSVEENDGKFVITLAGKLAVLIMQDIGANIEPEASGT
                     ACLPMMFPYSLLASHAVRMSSQAAVEGGQKSESTLSDIFAQGFDKDLGEFDRQLERYQA
                     LLSPAGSNGRGHETPVAVNEAADVAKTKTVVSKN"
     CDS             complement(16559..16843)
                     /locus_tag="ctg5_122"
                     /transl_table=11
                     /translation="MAYARNPFLQASRAATSSTKPSRGFWTSPAGKHLRLAKNCFALAK
                     QHRAAGNKKKYWSLLNAGRSALALSRHEVSLWKRGQSVRRRSYAIHRAV"
     CDS             17088..17372
                     /locus_tag="ctg5_123"
                     /transl_table=11
                     /translation="VHARLGETVQQRLHAELAAVHVRKEGRCASFPGLLQPATKGLLCV
                     LCEWRTSLFAASSDVLHLSTAAEHYRVSVEIDDLGEPRHPVRAASSRRV"
     CDS             17900..18472
                     /locus_tag="ctg5_124"
                     /transl_table=11
                     /translation="MADDYLKYGDRLRIINAYGGVGLGGYLGVGGESKVPSAVDNVGTY
                     ASLSGQELATQWTIMAAPGSSKTPGQNVCSGDQIRLQNYQDESYLALFSSNPPGDSGYP
                     VATTTTLNDDTIAAAWYVLISSQNKRNDPNLSDTNDIYLVATFGTLAGALDTNGVGAGG
                     FKYSVTGARLLNRDGGSGSWQVVKIRN"
     CDS             19521..19748
                     /locus_tag="ctg5_125"
                     /transl_table=11
                     /translation="MNRRDNMHTYKARIDRPEMKVSRVAGERDRDLLRMALNSTARESD
                     KSQPRLYYRPANLARAKTRAGIGRPKYFQP"
     CDS             19826..20530
                     /gene_functions="regulatory (smcogs) SMCOG1071:GntR family
                     transcriptional regulator (Score: 66.7; E-value: 4.7e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg5_126"
                     /transl_table=11
                     /translation="MRCCKNAPPRRGVDLNFDIEPEPAKADIAYDAIRRLLHSYGRVPD
                     QHLREQDLASKLDIGRTPVREALQRLAAEGKIQYIPQRGFFTRPMSENTLLDFYVVGRE
                     TLISALNRMRPQAPESWSVSDKLSPDELALRTEAIFAKIAEEAANCEACKIVHRFCFCT
                     HPLRMEITASDLRPAFVKSLGRLSAAMSELGVATDRAQSALMNHLDLEQGAVSRVVHEV
                     NERGLTGFSRPA"
     PFAM_domain     19910..20083
                     /aSDomain="GntR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00392.23"
                     /description="Bacterial regulatory proteins, gntR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_126_0033"
                     /evalue="4.90E-14"
                     /label="ctg5_126"
                     /locus_tag="ctg5_126"
                     /protein_end="86"
                     /protein_start="28"
                     /score="51.8"
                     /tool="antismash"
                     /translation="AYDAIRRLLHSYGRVPDQHLREQDLASKLDIGRTPVREALQRLAA
                     EGKIQYIPQRGFF"
     CDS             complement(20664..20918)
                     /locus_tag="ctg5_127"
                     /transl_table=11
                     /translation="VGRDLQRQGGAVIMFAFSRREMMADLVKTRGRGKPASALWLQLIC
                     EANRVLVDGCAEPCIEREKDWDHTSSEGPAKMISNCRRI"
ORIGIN
        1 gtggtgaaag cacgaagcgg caaaaatgct aagggatcga gcgacgttga gcagaagata
       61 gacatcgaag cgatcttgcg cgaccgcatg tccgatttct cgccctcgga gcaaagcctg
      121 gccgcctata tcttggataa tatccagata ttgcccttcg agaccggcag cagcatagct
      181 gaggcggtgg gcgtcagcga aatgaccgtc acgcggttcg ttcgtggcct cggtttcgag
      241 aacctgcgag acctcaagaa gcggttgcgc gtcgcggtcg cggagaagga cagcgaagtc
      301 gacgactata tggcccgctt tccgatgcgc gaaggccgac agcagatgct gcaggaaagc
      361 ctgcggctgg aactcgacgc tatcgtgaag gcctacgcct tgactaccac cgacgcgtgg
      421 gacgaggccg caaacctgct cgcgaaggcg cgcaccatct atgtcgtcgg cttccaggcc
      481 tcgaaggggc tggccatgga tttcgccagc cgcctgctct gggcgcgctc taacgtgatt
      541 ttcatcgaca acgcttcggg cacgtttggc gagatcatca atgcagatcc caagcagagc
      601 gcagtcgttc tcgttgacac ggcctcgtac gcgacgcgcg gcatcaagct gctggagaag
      661 ctgaagtcga tggacatgcc gttggtcatc gtcaccgaca agttcagtca ctgggctttt
      721 gcctatacgc gcttcgtctt tgaggcgcat acccatgtga aaaccttctg ggattctacg
      781 gcaagcctca gtgtggtact caatctgctc atcgacgccg ttgccatcaa actagggccg
      841 aaggctaagg cgaacttcgc catgatgagc gacatgggca ccctcttcgg ggagttcgtc
      901 ggaggcagct atctccgccg taacgattga tccatcccaa accgcaaacg agagcatgca
      961 tgaccagtat ttcgccattc cgtgatccga ctgcacccgg caatcctctc tttccgaggc
     1021 aagactggga ccgcgcgccc tggaatcgct ggacgttcca acatgtccgg gatctgctgc
     1081 cgaccacaaa ggtctggcgc ggagcggggc cagcaagcct gttgttggcc gatcttcggg
     1141 atatcgatgt cattcccttc gtggcggagg gggaggccca taccattggc agcttcctcg
     1201 agacgagcta tgccgatggt ttcctggtgc tccatggcgg caagatcgtt gccgagcact
     1261 acctgaacgg catgacgtcg catacccagc acctgtcgca atctgttgcc aagtctgtcg
     1321 tcggcaccgt ggcgggcatc ctaatcggcc gaggagtggt cgacccggcc gcgtccctga
     1381 cgcattatct gccggagctg gaggcgaccg cctaccgcgg cgctactgtc cagcacgtgc
     1441 tcgacatgac cagcggcgtg gtcttcgacg agacttacac tgcgcccgac tcccacatgg
     1501 cgcagctgga tgtcgccagc ggctggaaga atggtcagaa cccgaactgg cacaagaata
     1561 tctgggacct ggtcctgtct ttgaaggatc tagagtgccc gcacggtacc tccttccgct
     1621 atcgctcgat cgagacggat gtactatcct tcgttctcga gcgcgccgcc gctaccccgc
     1681 ttgcagaact cgtcagccgt gaattgtggg cgccgatggg ggcggaggaa gacgcctatt
     1741 tcaccgtgga cgctgcgggc tatgctctgg gtgacggcgg gttcaatgcg actcttcgcg
     1801 actatgctcg tttcgccctg ctgcatcttc gcggcggcga gatcaacggg cggcgtatcg
     1861 tccccagcga gtggattgcc gggacacggt tcggggcaga tccgaaactc ttcggcggca
     1921 tctatcaaga ggttctgccg gccggcgcat atcacaacca gttctggatc gaggatactg
     1981 cacgcggcgt ctacatggcc cgcggggttt tcgggcaact gatttacatc gacccggtgg
     2041 cggatttcgc ggcggttgtc ctgtcgagct ggccggaatt tgtcagcacg acgcggacgc
     2101 ggacagcgct ggcggcggtg acggctgtaa gagaagcgct gttgtagtag caatcgggct
     2161 attcccctgt tcaggttgac gtgatcgcga gaagctacac cgacatcgct caaccatttt
     2221 cctgagctgc gccgcaacac gttcgaggat cagcagatac cggatctcaa cggctactac
     2281 tgcgtgacgg cgaatgcgat ggcacgtgag cgacgtgcca agctgcgtaa gcttgcgcgg
     2341 ttctcgcttc tgcgtcagtc ggtgatcggg cgcatcctgc atggctggtc gccgcagcag
     2401 attgccggtc ggatgcgacc ggagcggcat ccgatctcta tcatcatgag acgatctata
     2461 acttcgccta tttctcggac ggtcacgcca tcaaactgtg gggacacctg ccggagcatc
     2521 gtccagacgc cggcccggta cgccaggcgc cgtcatgtcc gggtttttag ccgggaggtc
     2581 aacattctga accccgatgt ggtcgccgca cgcaagcagt tcgggtatcg ggaatgcgtt
     2641 ctgatgcagt tccgcaagaa gttcggaaag gccaacgtga cgtcgctggt cgaacgggtc
     2701 atccgattcc gatgatggac gacttaacag gctgctgaaa ttgacgctgc gttgccggcg
     2761 cccttcctgc cgcgcgacgc gatcgtcgcc gaggccattg ccacttggat cggccagaag
     2821 gagcactcat cgaacagcac ggcgtgatcg atcaagccga cagcttatga aatgaggtaa
     2881 ccgctgccgg tcgtcagcac cgtccggcaa gaattcaaga ggccctcccc gcttccgtgg
     2941 ggagggcctc atttcttcct attccgccgc cacttccgct tcctcggggt gattggagag
     3001 ggagccgccg gactggcggt tccagaggtc ggcatagatg ccgcctcccg cgatcagttc
     3061 gctgtgcgaa ccggcctcta tgatccgccc cttgtcgagc acgatcagcc ggtccatctc
     3121 cgtaagcgtc gaaagtcggt gggcgatcgc gatcaccgtc ttgccctcca tcaaggtgaa
     3181 gaggtttttc tggatcgccg cctcgacttc cgaatcgagt gccgaggttg cctcgtcgag
     3241 caccaggatc ggcgcgtcct tcaggaagat tcgggcgatc gcgatgcgct gccgctggcc
     3301 gccggagagc ttgacgccgc gttcgccgac ctgcgcattc agcccttcgc ggccctgcaa
     3361 gtcgacgaga ccttcgatga actcccaggc attggcgcgt ttggcggcct cgatcacctc
     3421 ggcgtccgtt gcatcggggc gaccataggc gatgttgtcg cggatcgagc gatgcagcag
     3481 cgaggtgtcc tgcgtcacca cgccgatcag cgagcgcagg ctttcctgcg agacgccggc
     3541 gatatcctgc ccgtcgatgg tgatgcggcc ggcctccaga tcgtagaagc gcagcaacag
     3601 cttcatcagc gtcgtcttgc cggcgccgga acggccgact aggccgacct tttcgccggc
     3661 cttgatgtcg agcgaaaggt tgtcgatgac gcccttgctc ttgccgtagt ggaagcggat
     3721 gcggtcgtag tgaatcgcac ccttcttcgc cgtcagggtg ggtgcgcccg gcttgtcgac
     3781 gatgtcgtgc tgtttgctca tcatctccat gccgtcatag accgtgccga tattctcgaa
     3841 cagcgccgtg acttcccgca tgatccattg cgacatgaag ttgaagcgca tggcaagacc
     3901 gatggcgatg gcgatggcgc cgaccgagat cgctccgctc agccagaacc agatcgactg
     3961 gcccgagatg acgaagagcg caacacagtt gttcaggtag acgcagatgt ggaagagcgc
     4021 caccttgcgc aactgcttgt gcacgatctg caggaactcg tccatgcttt ccttggcgta
     4081 gacctcctcg cggcccgcat gcgaaaacag cttgaccgtc gcgatattcg tatagctgtc
     4141 gaccacgcgc cccgtcatca tcgagcgcgc atccgcctgc gccgcggcaa tcttgcgaag
     4201 ccgcggcacg aaataggcga caatgctgat atagaccgcc agccagacga ggatcgggat
     4261 catcagccac cagtcggctg ccgcaatcac gacgatcatc gtcaggaagt aggtcacgac
     4321 atagacgaag acatcgagga tcctgatcac cgtttcgcgt acggcaatcg aggtctgcat
     4381 caccttggtc ccgacgcacc cggccgcctc gttggcgaag aacgacatgc tgtggcgcag
     4441 caggaagcgg tgcatctgcc agcgtgcgct catctgataa ttgccgagca tcatctgatg
     4501 catgatgaaa gactcgagcc cggccgtcag cggcaggccg accagcacca gcgccgccat
     4561 ccagaaaagc ttgtgacctt ctctctccag gaaggtggcg cggtcggcat tagtcagcca
     4621 gccgacgatg tcgccgagga actggaagag ggccacttcg ccgatagcga tcagcgccgt
     4681 cagcacggct atcaagccga gccaaggcgc agccggtttg ctgtagtgcc agcaaaaagc
     4741 aaagagacct ttaggagggg cgacgggctc ctcgctcgga aagggattga ggcgctgttc
     4801 gaaccagcca aacattgatt gctccaagcg gttgctctca gttgattttc ccatcgtcgt
     4861 cacgacgttt cctccaggtt ttgggccgtt tctcgagtga cggcagcaac caggctgccg
     4921 tctttacccg agaacaactt tcaatcgtgg tttcagatgg cgctggaggc gcagcggggg
     4981 cggtctcacc tcaagcctga aaaaacttgt ccgttccgag ggcctccata gctgcggcaa
     5041 tccgagagag cgcaagaacg taggcggcgg tgcgcagggt gatgttcttg tctcgcgcat
     5101 atgccaaaac ggcgtcggct tcgctttcca tcttcgtctt cagccacgca tgaacctgtt
     5161 cgagggtcca tcgttcgccc tggcggttct gcacccattc gaggtacgag accgtgacgc
     5221 cacccgcatt cacgaggata tcgggaatga tttcgacgtt catggcctcg aggatctcgt
     5281 cggcctccgg ggtgaccggg ccgttggcga gttcgacaat gaccctggcc tttatgcttg
     5341 ccgcgttgcc ctcgtgaacc atgttctcta ccgctgctaa gatgaggatg tcgcattcga
     5401 ccgacacgag ctcgtcgcca gaaatctcgg acacaccagc tgaacctgcc atgctagtga
     5461 cacttccatg gcgcttggcg gccagcagtt tgctgatgtc gaggcccgcc ggggcatgga
     5521 ccgcaccctt ggagtccgag accgcgttga tcttgcatcc gtcggcggca agcagcttgg
     5581 cgatgtgctt gccggcattg ccaaatccct ggatcgccac tcgtgttcca tgctccaatt
     5641 tgagagtgtc ggctttatat cgcatgatgt tataggctcc gcgtgctgtc gcatcgtcgc
     5701 gcccgcgcga gccgccaagg gcgacgggtt tgccggtaat caccgctggc gtcctcttgc
     5761 cgacaatggt gctgtattcg tccatcatcc acgccatgat cttttcattg gtgccgacat
     5821 caggcgctgg aatgtcccga tctggaccaa tgaccgcagc gaaagcccgg atgtaggcgc
     5881 ggccgaggcg ttcctgctcc gtgttggaga ggccgcgagg atccaccttc acgccgccct
     5941 ttccgccgcc aaatggcagg cccatcagcg cgttcttcaa ggtcattagc aggccaagcg
     6001 tttccacctc atcggcgttc accatctgat cccagcggat gccgcccttc gtaggaccga
     6061 ggctatcgtc atagcgacag cgccacccga taaaacactt ggtcgacccg tcgtccatga
     6121 ggatcgacag acgcgcttgc gtcgtctcga gcggtttctt cagcttttcg agaaaacctg
     6181 gatgaagatc caggtgctcg gctgcttcaa tgacgcgttc cagcgcaatt ttcagcatgg
     6241 ggttcttcat agttagttcc tcactttcaa aggttgggag acttgcacgt cagcggccac
     6301 gcgtcccccg gcaccaaccc gatgcagttt gtgcctgagt ccccctagga ctcgtcgtgc
     6361 caagccgatc gcgcggtgat aacttgcggt ttcggcgagt ttgctttcgc caggttccgc
     6421 agtgcgacag cttttagggc cccagttttg gtctgccctt caaccgggag tgacgttgcc
     6481 cgaggagtcg cccccatttg gcgtagtctg cctttccgaa cttccagttc ttgacacgtt
     6541 cgattcgacg cttgcacagg atcaatcgcg cgaaatcgac cagtggctgg caaccgatga
     6601 ggattttccg cccaagttcg acaagggcgg cgagcgtatt ctgggatgta gtggatttgc
     6661 caatacctcc ctttccgtaa aacgcgatct gacgcagagc agccattagt gcttcctttt
     6721 cgtgttcgaa ccgaccgagg tgttgccgcg acaccggacg cggctggtcc cgtcgcagcc
     6781 cgagaacaat tttcaagcgt cgtgccaatt gagctgattg atggggcagg tcgaaattac
     6841 gtgctgccac agacacttag agggataaaa taccggaccg aagaatccta aagcgtgtca
     6901 cgaagccgac aaaggtgacg acaatgtcgt acatatgtcg tgagggtcct gaagaggccg
     6961 cggaatagaa gcgccaatgt gcaagcaatt cttggtcgaa tgagccgcac ttgatgcaaa
     7021 tgctggcaat ggaaagcggc gcggtgctct agcgaaatcg tttgcggtta aaaatctcgc
     7081 aagcagtgtt gcacccctgc caagcgcatg cagccacccg tgtcgcaaac ctgacaaagc
     7141 tgtcgcactg tcgactacta gccaacccga ttccccccga aatccgccag ctaatcaccg
     7201 cgcaatcggc ttggcacgac gagtgctagg accgaccgag acaccttgac gactcgacgc
     7261 tctctaacca cgcggtggcc aatcacctga tagccaaccg gctgaactgg aaggctggct
     7321 gacgacagga cggatgacgt ggatcatgct tggaccgtcg tcgtgagagt acctgcgtgc
     7381 ctgcgcgtca acattcacca aaggagcccc catgcgtatc gactcgattt cgattggcaa
     7441 gaacccgccg gacgacgtga atgtcattgt cgaggtgccg gtcggcggcc agccgattga
     7501 gtataaaatg aacaaggaat ccggtgcact cgtcgtcgaa cgcttcctct ccacgccgat
     7561 ggcctatccg ggcaattatg gctttgtgcc gcacacgatg tcagaagatg gcgattcgat
     7621 cgacgtcctg atagtagaca ctcgaccact cgttgagcgc tgcgttataa atgtgcgtcc
     7681 gataggtgtt ctggtcatgg aagagaatgg tcgcaaggac gagaagataa tcgccgtgcc
     7741 gatggcgaat ttgacgcgcc tctacgacaa ggttagggac tacaccgacc tgccggaaat
     7801 ctccctgaag cagatcgagt acttcttctc gtactacaaa gatctgaagc ccggcgagtg
     7861 ggtgaagata gccggctgga aggacgtcaa tgtcgccaaa aagatgattc ttgaggcggc
     7921 cggccgctac aattcgaaaa cctgattggc aatcgggaga cccgcgaggg gtcgtcgacg
     7981 gccgaagcgg agcaggctaa gtcacaggat tatggacaac caataaccaa gcactggccc
     8041 gtagttccat aagtatgctt acgccacttc tttatgtagc cgggtgggtt caaggatgaa
     8101 gcgcgacttg caatagataa caacgattta tccctgcaag gaacgagata tgaagcgcac
     8161 ctactcccag atcgatatgg aggaacgccg caagattgcc cgctggcgca cggctgggat
     8221 cagcgttgac gtgatcgccg agaagctgca ccggcatcgc tcaaccattt tccgtgagct
     8281 gcgccgcaat acgttcgagg atcgtgagat gccggacctc aacggttact actgcgtgat
     8341 ggccaatgac atggcgcgag aacggcgtgc caagctgcgc aaacttgccc ggttctcgca
     8401 gctgcgccaa tcggtgatcg agcgcatcat gcatggctgg tcgccacaac agatcgctgg
     8461 ccgattgcag cttgagcgcc atccgatctc cgtcagccat gagacgatct ataagttcgc
     8521 ctattcctcg gacggtcacg cgatcaaact gtggcgacac ctgccggagc atcgtgccag
     8581 acgcaggccg cgccacgcca gacgccgcca tggcaggcgg ttcacccgga tgtcaacatt
     8641 ctctaccggc cagacgccgt cgccgagcgc aaacagttcg ggcattggga atgcgatctc
     8701 atccagtttc gcaagaagtt cggaaaggcc aacgtgacgt cgctggtcga acgggtcagc
     8761 cgatttgccg tcttgctgcg caacaatgac cggcaatcga ggccggtgat ggacggcctg
     8821 atccaggtgc tgcaatccct gccccacctc gcccgccgct cgatcacctt cgatcgtggc
     8881 acggagttca ctgactggcc ttacctgcag gccagcatcg gagcgcagac atggttttgc
     8941 gatccgcaat ccccgtggca gaagggcacc gtcgagaaca ccaatagacg ggccaggaaa
     9001 tggctttcga gagaggtcga tccactgtct ctcagcgacc gcgatctgac cgagatctgc
     9061 aaccgcctga acgcaacgcc acgcaaatgc ctcggctaca aaacaccggc agaagtcttc
     9121 cgccagaaac tcctcgccca aatccggcgc accggttagc ctctatcagc ctccaagtcg
     9181 cgcttcgcca tgaattcaca gtaatgcaaa tggtgcaaag tagcttcggg cttcaacgga
     9241 tttcgaacct ccggctcgag caagagggtg cttccttgga tagaatagag ttgatgatgc
     9301 ttcctcaagc cagacatgga aggctttgcc tggattggta cgattaatac gccattgagc
     9361 agcgaaggcg gaccaagctc ggttacgttc caaccggttg agactaagag ttgcacgagc
     9421 ttcgggtgcg tttcgacgat caccgaggtt atgccggcaa caaggcaaaa ttccatcacg
     9481 ccggtcatca agacatgtga cgccgatacc ccatttatta gaatttgacc ttccgcgaca
     9541 atacatcggg tccactcgaa tatctcgggc gaacgcggcc atgcttgccc tttcatgatc
     9601 tgcggataaa catccgataa gagatgaggt tcagtcgtcg ggagcaatcg cgtatatccc
     9661 acgacggtat cttcgaagaa caatgcaagg tgcagcgcac ggtcgtgatc gaactggtcg
     9721 atttctaatc cgtcatttct acgaagcgcc tcccagccaa gcctttccac gaattgctcg
     9781 tgccgaaagc gccaaatttt ctccattgct tgcccgcgtg attcgtggcg accgacgtaa
     9841 agtcttatca ttctgccccc ccaacatagt gcaagaatgc attagactcc cggtcgttta
     9901 aatgagtgaa attacctagt tttcacgcgt tcgccggcca acgccgtcgt cgatggtcct
     9961 gcgaagtgat aaggagtgcc taaaggtgac atggcgaacg gaccgcggtc catagtgttg
    10021 agattggcta aggtttgggg ttcacgcgcg ccttatcgga caatcgtgat cagacgtcat
    10081 cgaaattgcg gccctcaccc aggagggcgt tactttaccg aaggattccg taacgaaaac
    10141 tctccgctat catctgcgcc gaattgacga catcgagttt gcgttgaaca ttgagtatct
    10201 cattttggat ggttctatgc gagcggccta gaattgccgc gatctccacc gctgtcttgc
    10261 ccgcagcgca ccactgaatg atctctcgtt cacgcgcagt tattcttaaa aggcgcctgt
    10321 cttgggagct cacgtttttc gttaacaggc tgcgcactgt gttatgggcg taaattgata
    10381 tgatatgtag cgctcctctg gcagctcgcg acagatccac cttctctgcc ccgaaagtga
    10441 taattgcttg aaagccgtcg gcggtatgca gtggcacact gtaaccatcc ttcattttga
    10501 actctcgggc ctccatcata atccggcgcg catgacggcc gagctcttga ccctgcagtg
    10561 cttccgacca cacaaaggca ccgtcttgca ttttactcaa atggatcacg ggatcggcat
    10621 ggacgtaatt gcccgttgaa taacgttcaa accactcgta gggccatgcg ttcaacaaga
    10681 aatacggatc gatgcgctcc gtaggcaagg gtatgccgga cattgcaaag caactaaaac
    10741 caaagtggca cgctgttctg ttcaatgact tcagtatatc ctcactgctc ttcgctagtg
    10801 cagcgtctga tataaagtcg aacattacat ttgccgttgc caacgcctcg ctgtccactc
    10861 ttccctccag gacatgctac tcaaggcagc atttttcatg gtcgcttccg gtaggagcta
    10921 actctccgag tagccactgt agacgaaaaa cccagcgaag aggagccttg tctgtatctt
    10981 tggcaaagtt gcccagacaa cgaaaccagg tcaacagctc cgcctttgct tatgacaatg
    11041 tacttgcaaa tggcccggac ctgatgtcag agctggcttg acctggtgca aagtagcatc
    11101 gggcttcagc ggatttcgag cctccggctc gagcaagagg gtgtttcctt ggatagaata
    11161 gagttgatga tgcttcctca agccagacat ggaaggcttt gcctggattg gtacgatctc
    11221 gggcgaacgc ggccatgctt gccctttcat gatctgcgga taaacatccg ataagagatg
    11281 aggttcagtc gtcgggagca atcgcgtata tcccacgaca gtatcttcga agaacaatgc
    11341 aaggtgcagc gcacggtcgt gatcgaactg gtcgatttct aatccgtcat ttctacaaag
    11401 cgcctcccag ccaagccttt ccacgaattg ctcgtgccga aagcgccaaa ttttctccat
    11461 tgcttgcccg cgtgattcgt ggcgaccgac gtaaagtctt atcattctgc cccccatcat
    11521 agtgcaagaa tgcattagac ccccggtcgt ttaaatgagt gaaattacct agttttcacg
    11581 cgttcgccgg ccaacgccgt cgtcgatggt cctgcgaagt gataaggagt gcctaaaggt
    11641 gtcgagcaga agaacggatc ggtcgtccgg cggggattgc cggctatcat cgccacgaag
    11701 gcgttgaagc tgcggcgacg ctcgcggacc tataccgttc aatgcgtttg ttcgtaaact
    11761 tctttcaacc gtcgttcaaa ctcctggaaa agcggcgtga tggcacattg gtcaagaaaa
    11821 gatacgcttc tcccgcgaca ccgcatcagc ggctgaagac ggatccaaga acgtcgaccg
    11881 aggttcgcaa tcgcctattg cacatgagcg agcaactcga ctccgtaaag cttctccgcg
    11941 gcattcgtgc gggacaacag cgcctcgttg acatcgctca ccagggcgca ccatcaaccg
    12001 acgctcctga tatcgagagc tttctacaaa gcttgcgtgt cgcttggaca gacgggaagg
    12061 ttcgtccgac ggcgaaagcg aagccgaaac tcaagggtga gcggcggcga cccgacccgc
    12121 tcgttagcgt tacggaagat ctccgtgcat ggttccagga ggaaccatgg agaaccggcc
    12181 gggaactatt ggagaggctt cagtccattt atccaggtga atatctggat ggcctaataa
    12241 ggacgtgcag cggcgagtga aagactggcg tcgggatggt gcgcatacga tgatcttcgg
    12301 aatcgacccc agcagaacaa cggagctgcc ctaacgcgaa aggagcattt tggtgaggca
    12361 ataggcagtt cattcaggag cattctccaa tgaggctata cgaatctcac cttgtttgcc
    12421 gctacgcacc gtggggctta agctgcgtga acggctgggc ttaaagggcg ccgccccggc
    12481 gggcgtctgt atgttttctt acgaagtttt cgtttcttgt gccttcggag accaattatt
    12541 tatgctgtga cactgcagaa gggccgccaa tggcagctgc cgatgtaaag tgggttggcg
    12601 atttgcagta attttattca cacggtgtag ccttcctagc caggtggtat tcctcgacgt
    12661 cgtgttgcgc ggcaatgtgc tgcaaaatgc aatcaacgac atcggtatcg cgtgtatcct
    12721 cattctgagg aacgacaagc caaccacgtt cgcaagccat ctcctgcaag acgttctgaa
    12781 tctttgtctg ataggcgcag taagcgtcgc gcggatcgcc gcgataaccg tcccaacgcc
    12841 ccatctcggt ctctttgaag accgtgcgcc ggtgccaaga tacatgcggc tctatctcca
    12901 acaggacgac tagatcaggc tcggcagccc gatcgaaata atcgagaagc tgggctctgt
    12961 cgatcttcgc tcggcaatgc gctttggcga ccactctgaa ctgcgaaccg tccataacgg
    13021 tgatgagatt gccaaacctg ggctctctgc gaagcatttg gcccacggca gaaaaccagg
    13081 atgcgagcaa aaacaaataa aaatgggttc cgagcaggtc aatcttcggt tcgccctgtt
    13141 caggccaaat gatttccttt agcaggcgaa gccgactatc agtgaaagcg tctccgaatt
    13201 ctatgtcgct cttattcaaa taacgggcca gatacccccc atcacgcagg ttatgagcca
    13261 actttcgggc aatatgagtc ttgcccgctc catcaattcc ttcgattgct ataagcatgc
    13321 tccactacct cccgcaaatg gtctgcgctt atcgcagtat tgccgcccgt tgatcggctc
    13381 ggattttcgg atgtgtactt ccgcgccagt ttattgtgcg gcaattgtct gcacatcatg
    13441 taactcctcg gccgcagttt cgcgaagaca tgccgcgatg gaggccccga cataatgtcc
    13501 gctgacaagg gcggggacga ggccgcgaaa ccggccgacg acatcgccgc aataccagat
    13561 ccgcccacta tgattctgca aggcggcatc aacggtcggg aaggcaccaa caccctcgac
    13621 tgatgggaaa atgcagacag tctctggcgt cgccatgtcc ggaaactgcg tgatgagcat
    13681 acgcgcgctt tcggcgagga tcctatagag ttcgggatgt aatagagcgg ccacgtcgcc
    13741 cctgctgaac ttctgccgcg ggaaccaggg acgatcagcc tttccgaatt caagcgcttg
    13801 ggatatggaa gggcgatcta ggaattcggt gagtggctgc catgtcgccg tcgtatcgct
    13861 ccccaaccgc tgttgcaaat cggcccaaat ctgtcgacct ctgtcgagat tattcccgcc
    13921 gaagcgcgcc agtaaaccga aattggagta gccggtcggg ggtccgtccg accgaccgga
    13981 aagagcagca gtgccaccat aggggatcat ccaaacctcc ccgtcgcgac aagtgcaaaa
    14041 ggttcgcact tccgtacacg ccgcatcgag aatgtatttc acgtctgggc gtttaacggc
    14101 gttaaggaac ccaactccgt taggatgttc gatacggata ccaaactcgt atcgcaggtc
    14161 ggtcatggcg atcggcgccg tcatcatgga ccgtagtgcc tgcggaccga agcgcccagt
    14221 tgcgatcgca agatgggtga aaaactcctc tctcagatcg ccgtccgctc cacgactttg
    14281 cacgaggtag ccttgtggcg agggaatgat catttccacg cgcgtgttgg ccaagatgag
    14341 gttgctgaac tcatgcatca tggcggctat cagcgcgttt cgctgcgcca acgagccgta
    14401 ggtcgacgga tagtccttgc atatcatggg ctggcccgtg ccgagaaagc tggtttcggt
    14461 gtccggatca aaagggggcg ccggaatgcc cacctccgcc agctggcgtt cgattgcgcc
    14521 ataggcatcc tcaagacggc aacggccctc tagcgtgtaa agatgtgtgc cggatggaaa
    14581 aaagctgaac ttgccgtcgg agaaaaggcc ggcaccacca attccgcttc ctagatggtc
    14641 tgccacgtca tgcttacgtt ctgcaagcgt acggccagcc tcgaacaaga ggaatttaat
    14701 acgctgtttg gcaagagcct ggccaactgc caggccggcc ggccctccac cgattattgc
    14761 tacgcgttcc accgtttgct cctcatataa ggatcgcctt gccaggcggc gaccaccttt
    14821 gatcgctagc tgcaatagct tagccatgtt gtaattgccg tgtcgcaagg ccggccgcgg
    14881 gtcccgcctc aagcgagctg aagatcactg atgactgtac gcgataacag cttagggaca
    14941 atgtctccga agtccgcttc atccggccgt ccttgctgat ctggcatcag aagcgccaac
    15001 accttcaaag gaaccggcgc atcaaagagg cgacgaacct gttcaaggac gtagaagatt
    15061 gcagctgaaa agccgtactt gccggcaacc gcaagcaact cgggccagtc gatgtcctcg
    15121 gcatgaaggc gcaacagcgc gtcgatgtcg cccagcatct gcaatttcag ggtgccatgt
    15181 tggtaggctt caaaatagat gcgggcagcg ctgaaccaca gaacgctagt cagcgactga
    15241 caatgcactt ctcgaccgag caacctgcgg ggaccggcgc cgcgccagac gtctacctcc
    15301 tccatgccag ctccaagact gaagtggatg tcgacgaaca ccggcatccg caccgagcca
    15361 tcgtcttgga cgaaggattt gatctgccgc gttcgccatt ctggcgcgat tagggtcgta
    15421 tcgaacttcg gccgaatctc ctcgaccata gtgactgaat gtagcgcgta cttatgctcg
    15481 agcgtctggt gtgtgatctt gcggaacatg tgtgtgaaga caccatccgc cggattgaat
    15541 actccgtgct gataacccaa tcggtaaagc tctttctgca ctcgccagac atctgctttg
    15601 cgcaccataa tgtccaaatc ctgcatcggg cgcagtgccg ggtcggaata tagcagagct
    15661 gccaatagag gacccttgaa caaatagtgt tccagatcgc acgcacgaaa atgtcctaga
    15721 agttcaccaa ggcgacggaa ttgtacctcg ctccgcgcct tcgacaactg cgaccacata
    15781 tgtatgtagt ggacgaccca ttctggtgtc cggggaagca aggctagtct attgaggtgg
    15841 aaaccgcaca acggcaatgt ctgatagctc tcggcacgcc aaaggacgaa tgaccaatcc
    15901 agatccgaat cgacaatccg ctgcaggcgc acgtcatcgg agggcgtcag gtccggtcta
    15961 caagtcagta ggagaaaagt ctcctctcgg gacagctgaa ccattgttgc tctccttcta
    16021 tcctcttaat ttttcgagac gaccgttttt gttttagcga catcggcggc ttcattcacg
    16081 gcaaccggcg tctcgtgccc gcgcccgttc gatccagctg gcgatagcag agcctgataa
    16141 cgttcgagtt ggcgatcgaa ttctcctaaa tccttgtcaa agccctgtgc aaagatgtcg
    16201 gagagtgtgg actcgctctt ctgtcccccc tcgacagcgg cctgagagct catccggacg
    16261 gcatgggatg caagcaggct atagggaaac atcatgggca agcaggcagt gccagaagct
    16321 tcgggttcga tgtttgcccc aatatcttgc ataatcagaa cagccagctt ccccgccaac
    16381 gtgatgacga acttgccgtc gttctcttct accgaatatc caaaaagcaa cgagtcgctc
    16441 atcttagtta ttcctcccta gaccgaaatg cagccaaaag accgttgcct cgggctgcgc
    16501 agaaacaatt gccgcggaat gcactcgcga gaatacattc cgcgccggag ggacacacct
    16561 agacggcgcg atggatcgcg taagacctgc gccggacact ctgcccgcgc ttccaaaggg
    16621 acacctcgtg ccgggaaagg gccaaagcac tgcggccggc attcagcagg ctccaatact
    16681 tcttcttgtt gcctgccgcc ctatgctgtt tcgccaatgc gaagcagttc ttggctagac
    16741 gtaggtgttt tccagctggc gaagtccaaa aaccgcggct aggttttgtc gaagatgttg
    16801 ctgcacgcga tgcttgaaga aagggatttc ttgcataagc catttccatt ctcctctttt
    16861 gaagtcatgc gtcccgctat acgcaatctg tagttgccga tagccgatca ttcttttggg
    16921 tgtagtggtc gtataaaggt atttttcgta tgttgtgata accactgtga gctaaaaaag
    16981 gattcactta aataggtact attacttagc tttgccgacg tgctgagcaa caactcacgg
    17041 ccgctgatgt catttgacgg ttttcccgag ccactctcgg agacgcagtg cacgcgcgcc
    17101 tgggcgaaac tgttcagcag cgcctgcacg ctgagcttgc cgccgtgcat gttcggaaag
    17161 agggccgctg cgcctcgttt cctgggcttc ttcagccagc aacgaagggc ttgctgtgcg
    17221 tcctttgtga gtggcgtacc tcgctctttg cggcctcttc cgatgtattg cacctatcca
    17281 ccgcggccga acattaccgc gtctcggtcg agatcgatga cctcggagag ccccgccacc
    17341 ccgttcgcgc ggccagcagt agaagagtgt gatcgccgcg ttccggccat gtgcttcgat
    17401 ccgtacagtc cagaatcgct tcaatctcgg gcctggtgag aaactgaagc ctccgcttgt
    17461 cacatcgctc ggtaagctcc cggtggccgc cttgcgaggt tgatgcgaat atcggaagtc
    17521 cttctgtaat gggcgtactg cgcgctattc ccaatacgac tacaatctcg cgggagctgg
    17581 tcccgcttcc ggcaagtcgc agcatttatc gtaatgtctc atgctcagtc ttctctttgc
    17641 cggctcaaaa tgtcctcgat catcacgagg tatcgatgcc aaacgttgct gacccaggag
    17701 gtaatcttca gtgccgaaaa ttggccggtc tttgattgga acggtggccg ggttcacgtc
    17761 tgaaatccgc aacaaggccg ctcaattaag taaatttact catttactag cgccaccaac
    17821 ccaggttcaa gtgagacgca ttattaaacc tacgatggaa cgatcctttc gatcgtcaca
    17881 tcgctaccgg gagcgtaaaa tggcagacga ttatctcaaa tacggcgata gattgcgcat
    17941 catcaacgca tacggaggag tcgggcttgg cggctacctc ggtgttggcg gggaatcaaa
    18001 ggtacccagt gccgtggata atgtcggaac atatgcaagc ctatcaggac aagaacttgc
    18061 tacgcaatgg acaataatgg cggcgccggg ctcctctaaa acccctggac aaaacgtttg
    18121 cagcggtgat cagattcgcc ttcaaaatta ccaagatgaa agttatttgg cattattcag
    18181 cagcaatccg ccgggtgata gcggttatcc cgtggcaacc accaccactt tgaatgatga
    18241 tacgattgcg gccgcttggt acgtcctcat tagtagccaa aataaacgca atgatccaaa
    18301 tctgagcgac acaaacgaca tatatttggt agctaccttt ggtacgctgg caggcgcttt
    18361 ggataccaac ggcgtaggtg caggcggctt caaatacagc gtcacgggtg cgcgtctgct
    18421 caatcgtgac ggcggaagcg gctcttggca ggtagtgaaa atcagaaact gagcttcaaa
    18481 ttcatccatc cagcgttgta ccgttactgg cctcgtgtca agttaaggcg cgaggtccct
    18541 caagcggcct acagatgggc aagctctctc catacggtag ctcgccttag cttgggtcga
    18601 gcataggatg ccattgcggc ggtcgagagg gtgatttcct gccacgattt atggcggcgt
    18661 ttcgcagttt gcgatgttca gcagtgctcg ttcggttgcg gccaagatgg aagaggttgt
    18721 ggatcggatt gtaagtatga ggaactgctg gcgtgcggga ctgatttgaa ccgactcata
    18781 tggtgttccc cgcggtcggg ctgttggcgc gagacctcgc agcgattgtg aaatttcggc
    18841 tctgtccaac tgcacgtcgg aattctacct tcgatctccg tgctaaagag agccgtctag
    18901 aaggcaaaca gcgaattcgc cgccgctgca tggcttgcga caccgatcga tcaagcatca
    18961 ccagcgtcag cttgtcggtc ttgcgcatta actccaccta caggttgata aatacatgag
    19021 atccaaggcg ttaagccaaa gtcttcgtta cccacgcgct tgaaagtgcc tgatccccta
    19081 ccctgacaac ggcgatgata cacttccatt gcgtttccta tggtatttga ttttctcgaa
    19141 gaaattcact cccgtggcca tcggctccga ggtgaggaac taatcgagcc acctaaaatg
    19201 ttggaattgt ctagcaagac gaggaactta tccggctgct tgagcgattg gtaagcgaac
    19261 atggccagtt aaagattttg cgactcgcca actgagaatc gtgtgaccga acatgcgcag
    19321 ttgtttgatt aatacgtaca gtattatacg tttacttagt catccgcaga aagctaaaat
    19381 acaaaaactt acgctcgagc gataacccca aaatatcaaa aaatatatta tccttatata
    19441 ttgatctgtg gcgaggcgcc gtctagatct gctcaacacg cggcacgggg gcctaccccg
    19501 gtcagcgaag ggaggcttag atgaaccgac gtgacaacat gcacacatac aaagccagaa
    19561 ttgacaggcc agagatgaag gtcagccgtg tagctggaga acgtgaccgc gacctcttgc
    19621 gcatggcatt gaactcaact gcgagagaaa gtgataaaag ccaaccgcgg ctgtactaca
    19681 ggccggcgaa tctcgctcgg gccaaaactc gtgccggtat agggaggcca aaatattttc
    19741 agccttgaat tcggaacgac gcccgatatc aacgaataag atcctgtaga gtccttaaag
    19801 gacatcgaca gaggaaaact atcaaatgcg gtgttgcaag aacgcgcctc cacgtcgcgg
    19861 ggtcgattta aattttgaca ttgaaccaga acctgcaaag gccgatattg cctacgatgc
    19921 tattcggcga ttgctgcaca gttacggccg tgtgccggac caacatctca gggaacagga
    19981 tctggcgtct aagctcgata ttggtcgaac cccagtacgc gaagcacttc agcggctggc
    20041 ggcggaaggg aagatccaat acatccctca gagaggtttt ttcacgagac cgatgtcaga
    20101 aaatacactg ttggattttt atgttgttgg acgcgagacc ctcatttcgg ccttaaatcg
    20161 aatgcggccg caggcgccag agagctggag cgtgtcggac aaattgtccc ctgacgaact
    20221 cgccttaagg acagaagcga tattcgcaaa aatcgccgag gaagcggcca attgtgaggc
    20281 ttgcaaaatc gtccaccgat tttgtttttg tactcaccct ttacgaatgg aaataaccgc
    20341 gtcggatctt cggcccgcgt ttgtcaaaag cctcggaaga ctaagtgccg caatgtctga
    20401 attaggcgtg gcaacggacc gggcgcagtc cgcgttgatg aaccaccttg atctagaaca
    20461 gggtgccgtc tcaagggtcg tacacgaggt gaacgaacgt ggattaacag ggttttctcg
    20521 gccggcgtga atcttgtgat atcgcataac tgaagcccta aggctcgaat tcactcgacg
    20581 ccgctctgcg ttcgaaagac ctcgcaatga acgaaccggc ggagagaaaa gctcacctct
    20641 gcaatgctcg cagaataaga gcgttagatc ctgcgacagt tcgagatcat cttggcgggg
    20701 ccttcactgc ttgtgtggtc ccaatctttt tcccgctcaa tgcacggctc cgcacagccg
    20761 tcgacgagga ccctattcgc ctcacaaata agctgcagcc acagagccga tgcgggtttt
    20821 ccgcggccgc gtgtcttcac cagatcggcc atcatctctc gccggctgaa ggcgaacatg
    20881 atcacagcac cgccctgacg ttgaaggtca cgccccac
//
