LOCUS       c00006_NZ_SILH..       10387 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_SILH01000001.1 Rhizobium leguminosarum strain SM52 chrom_SM52,
            whole genome shotgun sequence.
ACCESSION   NZ_SILH01000001
VERSION     NZ_SILH01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:45:39
            Original ID  :: NZ_SILH01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2670294
            Orig. end    :: 2680681
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10387
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[2675294:2675681](-)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5387)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     cand_cluster    1..10387
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10387
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="4"
                     /rules="ectoine_synt"
                     /tool="antismash"
     CDS             579..752
                     /locus_tag="ctg6_2674"
                     /transl_table=11
                     /translation="MSKTNVRELQKRAERQVRNTSAGGHLGGTYFGQQPDGKTASSTNN
                     DSAKARPNNGSK"
     CDS             927..1859
                     /locus_tag="ctg6_2675"
                     /transl_table=11
                     /translation="VAFYSIDDAIRELAPALDKAPAGAVSGEWTATTMQAGHSSRTGGY
                     RDAEGNYVPEASRHPLDIISDVVEKLGASGMPRFNKVIIRWRKPKFPFMRGEITLETSY
                     DRTIVPRGPDDPIYETAAATRRVFWQSRGTVQEDFAAERGTANIHAQTKWFGPHRRILA
                     IHAPGRLTLATDGLSTPWAGISEPENGVECELFMEFDAATLDAAGIENWANLLINIGDL
                     VADGYRVARDVEKHGAILFCRLTEDYRPMTRIVLSRDAGRIDGLPFGSEPLILATPIKE
                     AEIEGQDLSDDWGAAAARNALAKRGIGSN"
     CDS             complement(1906..2349)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-141). E-value:
                     3.4e-08. Score: 25.8. Matches aSDomain:
                     nrpspksdomains_ctg6_2676_Polyketide_cyc2.1"
                     /NRPS_PKS="type: other"
                     /locus_tag="ctg6_2676"
                     /transl_table=11
                     /translation="MPSTIRLHRVLATTPEKVYRAFLEADALAKWLPPNGFLCTVHHSE
                     PVVGGTFRMSFRNFTTGNSHAFGGEYLELVPGERLRYTDRFDDPNLPGEMEVTVTLKKV
                     SVGTEVDIVQAGVPDVIPPEACYLGWQESLRNLARVVEPDIQE"
     PFAM_domain     complement(1924..2313)
                     /aSDomain="AHSA1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08327.13"
                     /description="Activator of Hsp90 ATPase homolog 1-like
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg6_2676_0113"
                     /evalue="4.60E-29"
                     /label="ctg6_2676"
                     /locus_tag="ctg6_2676"
                     /protein_end="142"
                     /protein_start="12"
                     /score="101.3"
                     /tool="antismash"
                     /translation="TTPEKVYRAFLEADALAKWLPPNGFLCTVHHSEPVVGGTFRMSFR
                     NFTTGNSHAFGGEYLELVPGERLRYTDRFDDPNLPGEMEVTVTLKKVSVGTEVDIVQAG
                     VPDVIPPEACYLGWQESLRNLARVVE"
     aSDomain        complement(1927..2337)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg6_2676_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="3.40E-08"
                     /label="ctg6_2676_Polyketide_cyc2.1"
                     /locus_tag="ctg6_2676"
                     /protein_end="141"
                     /protein_start="4"
                     /score="25.8"
                     /tool="antismash"
                     /translation="IRLHRVLATTPEKVYRAFLEADALAKWLPPNGFLCTVHHSEPVVG
                     GTFRMSFRNFTTGNSHAFGGEYLELVPGERLRYTDRFDDPNLPGEMEVTVTLKKVSVGT
                     EVDIVQAGVPDVIPPEACYLGWQESLRNLARVV"
     CDS             complement(2464..2877)
                     /locus_tag="ctg6_2677"
                     /transl_table=11
                     /translation="MTRKYTGQCACGAVRFAFDTDPNFVANCHCLDCKRATGGEAATFF
                     AVPQEDFTVISGSPKAFHYIAASGKGLDRNFCPDCGARLFSSNLESFPGLVFVTLGSLD
                     RPELIKPGVEMFTRRRLAWARPLDLPQFDGMPG"
     PFAM_domain     complement(2524..2799)
                     /aSDomain="GFA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04828.16"
                     /description="Glutathione-dependent formaldehyde-activating
                     enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg6_2677_0114"
                     /evalue="2.40E-25"
                     /label="ctg6_2677"
                     /locus_tag="ctg6_2677"
                     /protein_end="118"
                     /protein_start="26"
                     /score="88.8"
                     /tool="antismash"
                     /translation="NCHCLDCKRATGGEAATFFAVPQEDFTVISGSPKAFHYIAASGKG
                     LDRNFCPDCGARLFSSNLESFPGLVFVTLGSLDRPELIKPGVEMFTR"
     CDS             complement(3137..3829)
                     /locus_tag="ctg6_2678"
                     /transl_table=11
                     /translation="MKILMVLTSHDQLGNTGKKTGFWLEELAAPYFVFRDAGVDITLAS
                     PKGGQPPLDPKSNEPAFQTEDTRRFERDAAAMAALANTIKLPEIDQADYDSVFFPGGHG
                     PLWDLTNDRNALSLIEDMLSAGKPVALVCHAPGILTNVKAPDGKPIAKGRAVTGFTDSE
                     EEAMHLVEVVPYLLEDVLKEQGAKFSKTADWGVHVVQDGLLITGQNPASSKQGARTLLD
                     ALGKKAAA"
     PFAM_domain     complement(3167..3757)
                     /aSDomain="DJ-1_PfpI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01965.26"
                     /description="DJ-1/PfpI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg6_2678_0115"
                     /evalue="1.90E-14"
                     /label="ctg6_2678"
                     /locus_tag="ctg6_2678"
                     /protein_end="221"
                     /protein_start="24"
                     /score="53.9"
                     /tool="antismash"
                     /translation="EELAAPYFVFRDAGVDITLASPKGGQPPLDPKSNEPAFQTEDTRR
                     FERDAAAMAALANTIKLPEIDQADYDSVFFPGGHGPLWDLTNDRNALSLIEDMLSAGKP
                     VALVCHAPGILTNVKAPDGKPIAKGRAVTGFTDSEEEAMHLVEVVPYLLEDVLKEQGAK
                     FSKTADWGVHVVQDGLLITGQNPASSKQGARTLL"
     CDS             4298..4771
                     /locus_tag="ctg6_2679"
                     /transl_table=11
                     /translation="MINRYTSVATLSTVVFSLLAFSPASAVDMAQAQQQPAQAQPPAQG
                     QTPMQGQPGGTGATAAVSDQKIEAFAVAYLQVDKVRQEYSAKIGATKDETAKQQLQEEA
                     KKQMVDTVKASPDISVEEYSSILTAAQSDPALAKKVLEKIGTPPPGQRQQQQQ"
     PFAM_domain     4484..4717
                     /aSDomain="DUF4168"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13767.8"
                     /description="Domain of unknown function (DUF4168)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg6_2679_0116"
                     /evalue="4.90E-16"
                     /label="ctg6_2679"
                     /locus_tag="ctg6_2679"
                     /protein_end="140"
                     /protein_start="62"
                     /score="59.7"
                     /tool="antismash"
                     /translation="SDQKIEAFAVAYLQVDKVRQEYSAKIGATKDETAKQQLQEEAKKQ
                     MVDTVKASPDISVEEYSSILTAAQSDPALAKKV"
     CDS             complement(5001..5387)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_2680"
                     /sec_met_domain="ectoine_synt (E-value: 1.3e-32, bitscore:
                     110.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFVRNLKEVELTERFVDWGNGTSHRLLTKDDGMGFTVCHTVVRAN
                     SEALLQYRNHLEACYCIKGEGEVEDMDGNVFPIRAGDIYVLDKHDRHYLRGGKDQDLIL
                     VSIFNPPLTGTERHDLNNKSGSQY"
     PFAM_domain     complement(5025..5387)
                     /aSDomain="Ectoine_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06339.14"
                     /description="Ectoine synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg6_2680_0117"
                     /evalue="3.50E-40"
                     /label="ctg6_2680"
                     /locus_tag="ctg6_2680"
                     /protein_end="121"
                     /protein_start="0"
                     /score="137.2"
                     /tool="antismash"
                     /translation="MFVRNLKEVELTERFVDWGNGTSHRLLTKDDGMGFTVCHTVVRAN
                     SEALLQYRNHLEACYCIKGEGEVEDMDGNVFPIRAGDIYVLDKHDRHYLRGGKDQDLIL
                     VSIFNPPLTGTERHDLN"
     CDS             5518..6396
                     /gene_functions="regulatory (smcogs) SMCOG1031:LysR family
                     transcriptional regulator (Score: 196.8; E-value: 8.5e-60)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg6_2681"
                     /transl_table=11
                     /translation="MQLPPLNALRAFEATARLMSLSKAGDELHVTHAAISHQIKHLETW
                     LGRKLLQKSGRGVALTAAGGEYYRAVSGSLAAIAHATGNMRRDHNMRAITVGCIPSIAS
                     RWLVPALPSFQESDPDLDVRIVYARAEERFDDESLDVLITMGEDLSGGRESRLLFSRRN
                     QPVASGHYLAKRNWTIDDVSLAGADLLHDESADGWKEWFRKAGQKAPEPLRGPIFQDFN
                     MLATAVVAGHGVALCPVEVFRREIECGDLLVLSDIATAENQGYYVISNSWAKKPVRRFI
                     DWFMTECGSGA"
     PFAM_domain     5533..5709
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg6_2681_0118"
                     /evalue="8.30E-18"
                     /label="ctg6_2681"
                     /locus_tag="ctg6_2681"
                     /protein_end="64"
                     /protein_start="5"
                     /score="64.2"
                     /tool="antismash"
                     /translation="LNALRAFEATARLMSLSKAGDELHVTHAAISHQIKHLETWLGRKL
                     LQKSGRGVALTAAG"
     PFAM_domain     5791..6381
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg6_2681_0119"
                     /evalue="1.10E-23"
                     /label="ctg6_2681"
                     /locus_tag="ctg6_2681"
                     /protein_end="288"
                     /protein_start="91"
                     /score="83.8"
                     /tool="antismash"
                     /translation="RAITVGCIPSIASRWLVPALPSFQESDPDLDVRIVYARAEERFDD
                     ESLDVLITMGEDLSGGRESRLLFSRRNQPVASGHYLAKRNWTIDDVSLAGADLLHDESA
                     DGWKEWFRKAGQKAPEPLRGPIFQDFNMLATAVVAGHGVALCPVEVFRREIECGDLLVL
                     SDIATAENQGYYVISNSWAKKPVRRFIDWFMTEC"
     CDS             6620..8275
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 190.3; E-value:
                     1.3e-57)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_2682"
                     /transl_table=11
                     /translation="MQKIRAAPSALGQTEARASSSIDRLLFFDRDFNPVENLLGTELPD
                     SVKPAASFWEHFPELDKSAITLALRSLGDSAQPLQISGDFGAPASHGLTIYRIGDLFAV
                     VRSEESIDDERATLLHLATHDPLTGLPNRRQFSEDLAVLLRETAGSNETLSLMQLDLDD
                     FKPVNDTLGHPAGDKLLQLAASRIQECLTSDDRAYRLAGDEFTVISRGPGHPAKGHQLA
                     EALVDAFKKPFTIDGIALFVGASIGISAAPPDGTNPEQLMKASDVALYAAKKDGRGRAR
                     PFDPSMLELLEQRELLRRSLRMALVQQQFSIEYQPIAEGGSIVGFEALLRWNHPLLGKI
                     PPTAFIPMAEADGIMPEIGAWVLEQACREAMKWPQNYVVAVNVSAAEFLTSGLTDRVSQ
                     TLDLIGLPPDRLELEITESVLLERTVNNIDTLNTLNVLGIRISLDDFGTEYSSLSYLKT
                     FPFDTIKIDKYFITDLESDLKGQAIVRCIVNLAHDLDMQVTAEGVETPGQAEWLRGVGC
                     DRLQGYLISRPLPVEAIGEFITRAETSVRPALPQ"
     aSDomain        6977..7459
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg6_2682_0033"
                     /evalue="2.30E-36"
                     /identifier="TIGR00254"
                     /label="ctg6_2682"
                     /locus_tag="ctg6_2682"
                     /protein_end="280"
                     /protein_start="119"
                     /score="123.0"
                     /tool="antismash"
                     /translation="HLATHDPLTGLPNRRQFSEDLAVLLRETAGSNETLSLMQLDLDDF
                     KPVNDTLGHPAGDKLLQLAASRIQECLTSDDRAYRLAGDEFTVISRGPGHPAKGHQLAE
                     ALVDAFKKPFTIDGIALFVGASIGISAAPPDGTNPEQLMKASDVALYAAKKDGRGRA"
     PFAM_domain     6983..7453
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg6_2682_0120"
                     /evalue="3.60E-44"
                     /label="ctg6_2682"
                     /locus_tag="ctg6_2682"
                     /protein_end="278"
                     /protein_start="121"
                     /score="150.5"
                     /tool="antismash"
                     /translation="ATHDPLTGLPNRRQFSEDLAVLLRETAGSNETLSLMQLDLDDFKP
                     VNDTLGHPAGDKLLQLAASRIQECLTSDDRAYRLAGDEFTVISRGPGHPAKGHQLAEAL
                     VDAFKKPFTIDGIALFVGASIGISAAPPDGTNPEQLMKASDVALYAAKKDGRG"
     PFAM_domain     7514..8203
                     /aSDomain="EAL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00563.22"
                     /description="EAL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg6_2682_0121"
                     /evalue="2.90E-70"
                     /label="ctg6_2682"
                     /locus_tag="ctg6_2682"
                     /protein_end="528"
                     /protein_start="298"
                     /score="236.5"
                     /tool="antismash"
                     /translation="RSLRMALVQQQFSIEYQPIAEGGSIVGFEALLRWNHPLLGKIPPT
                     AFIPMAEADGIMPEIGAWVLEQACREAMKWPQNYVVAVNVSAAEFLTSGLTDRVSQTLD
                     LIGLPPDRLELEITESVLLERTVNNIDTLNTLNVLGIRISLDDFGTEYSSLSYLKTFPF
                     DTIKIDKYFITDLESDLKGQAIVRCIVNLAHDLDMQVTAEGVETPGQAEWLRGVGCDRL
                     QGYLISRP"
     CDS             8351..8860
                     /locus_tag="ctg6_2683"
                     /transl_table=11
                     /translation="LEQEAASFDDHAFAPMVSLELNVAMFKSRWQFCDRITEYLSDILG
                     QGHSDPARYSNFLSVATNELIELAFRSTSEPGRISFSLYRSATVNRLRIVFPGEEAFGR
                     KHANARSSERQPVPGAGSGYLVMKSDGTVLLSDLAAIFRATIRIEIDGGQGIQIIADFP
                     SAEDFR"
     CDS             8857..10029
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 82.2; E-value:
                     6.6e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_2684"
                     /transl_table=11
                     /translation="MSLLPQPFTVHFDPTNQELLLSGKMRPESATEIADALKVVQQSLE
                     KYSGIVYLNVKRLTHINMTAFVTLSDVLAASCRTRPERKIVIITSSVVAWSTSLFETLA
                     ASQPNLSVEVYDSAFYPGQSFVEDETFIPILRTQTKMTWRHERELLPRHGLRSGLVIAD
                     ICCGIGDFAALVQREFKPARLVALDHSVRSLEYARRVAVDFDLQGIEYTYGDASQMLLR
                     DNQFDFVTCRHSLQIFNRPEMLLRELYRICKPGGRVYITNEKNSHCLGEPHAETIRWTY
                     EEVAKLFRYFDMDVEMGPKSRHLLADAGFDSIKVDSFMVTNLDGDPQDFADIIEAWENV
                     YAGEMAVRRGDSLDFIRRFRQGFKDHVFAALHPKGYAGWPIWAASGRKPL"
     PFAM_domain     9343..9636
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08241.14"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg6_2684_0122"
                     /evalue="3.00E-17"
                     /label="ctg6_2684"
                     /locus_tag="ctg6_2684"
                     /protein_end="260"
                     /protein_start="162"
                     /score="63.1"
                     /tool="antismash"
                     /translation="DICCGIGDFAALVQREFKPARLVALDHSVRSLEYARRVAVDFDLQ
                     GIEYTYGDASQMLLRDNQFDFVTCRHSLQIFNRPEMLLRELYRICKPGGRVYI"
ORIGIN
        1 gcattgattc aagattagca aaccagcatg acacgcgttg aacatgcgat cgtgccgata
       61 ttatcggcaa caatgcccat atttcttaaa tcagaaccgg aatactcccc atccctaata
      121 aagtgttaac acatatactg tggaatgaaa gacgattttc ttgcgatggt aaatttatcc
      181 aggaattcgc tgcgagagac gccgaagtcg cagacctcga tcccgaccag cagtggggtg
      241 ggatggcggc gcgcaaggcg cttgcgaagc gcaggcccaa actttagagc ctttccgctt
      301 ttcctcgctt aggtcggcac cggctgctcc acgccgttca tcgggatgtt gtcccggatc
      361 ggctttctac aacgaagcca aaagaaggag ctccaaatgt ccgacgtgcg aatatttcca
      421 tcgggtcagc ggcagcgaag cgggacaccg acgacgggtg agcaaacgtt tcccccaagc
      481 ccgccgccga cgtaaaggac accgccctcc gcaaaaatat ggaaccgtgt cgtccgccat
      541 cggttgacca gatgtccacc tcaaacatgg agccgaaaat gagcaagacc aacgttcgtg
      601 aactccagaa acgcgccgaa cggcaggtga ggaacaccag cgccggcggc catctcggcg
      661 ggacatattt cgggcagcaa ccagacggaa aaaccgcctc gtcgaccaac aacgacagcg
      721 ccaaggcgcg cccgaacaac ggaagcaaat agcgccgcag gcctcacctc acctaggtaa
      781 ggaattctcc tgcgcccagg gatctgggcg cctcccctgc tcgcgacgtc cacctcgcta
      841 ttgatcggcg acgcctccgc gctagcttct gctcgcggcc gagcgaccgc gggggatacg
      901 atctttgggc gaaggcggag ggcgacgtgg cattctattc gattgacgat gcgatccggg
      961 aacttgcacc ggctctcgac aaggcgccgg cgggcgcggt cagcggcgaa tggacagcca
     1021 ccacgatgca ggcagggcat tcctcccgga cgggcggcta ccgcgatgcc gagggaaact
     1081 atgtccctga ggcctccagg catccgctcg atatcatctc tgatgtcgtt gaaaagctcg
     1141 gtgcatcagg gatgccccgc ttcaacaagg tgataatccg ctggaggaag ccgaagttcc
     1201 ccttcatgcg gggagagatc acgctcgaaa cgagttatga ccggacgatc gtgccgcgcg
     1261 gccccgacga cccgatctac gaaaccgctg ccgctacgcg gcgcgtcttc tggcagagcc
     1321 gcggtacagt ccaggaggat tttgccgcag agcgcggaac ggccaacatt cacgcccaga
     1381 cgaaatggtt cggcccgcac cgccggatcc tagccatcca tgcgccggga aggctgacgc
     1441 ttgccaccga cgggctgtcg accccctggg ccggcatatc cgagccggaa aacggcgtcg
     1501 aatgcgagct tttcatggaa ttcgacgccg cgacactgga tgcggccggg atcgaaaact
     1561 gggcgaacct gttgatcaac atcggcgacc tcgtggcaga cggttatcgt gtcgcccgcg
     1621 atgtcgagaa gcacggcgcc atcctgttct gccggctgac tgaggattac cgcccgatga
     1681 cccggatcgt gctcagccgt gacgcaggcc ggatcgacgg cctgcctttc ggctccgagc
     1741 cgctgatcct ggcaacgccg atcaaggaag ccgaaatcga ggggcaggac ctttccgacg
     1801 actggggcgc tgcggccgcc cgcaacgccc tggccaaacg cggcatcggc agtaattgat
     1861 gtcgcaggcg ccgggcggtt gccgcccggc aggcgcgatc ttgcgctatt cctggatgtc
     1921 gggttcgacg accctggcga ggtttcgcag cgactcctgc cagccgagat aacaagcctc
     1981 gggcggaatg acgtcgggca cccctgcctg tacgatatcc acctcggtgc cgaccgaaac
     2041 cttcttcagc gtcacggtga cttccatttc gcccggcagg ttgggatcgt cgaacctgtc
     2101 ggtgtagcgc agacgttcgc ccgggacgag ctcgagatat tcgccgccga aggcgtggct
     2161 gttgcccgtc gtgaagttgc ggaaggacat tctgaacgtg ccgccgacaa ccggctccga
     2221 atggtgcaca gtgcagagga agccgttcgg cggaagccac ttggcaagcg cgtccgcctc
     2281 caggaatgcg cgatagactt tctccggggt ggtcgccaga acgcggtgca ggcgtatggt
     2341 actcggcata gtcgtgatcc tttttggatt tacggaatgg acgaacctag gacggacgtg
     2401 gcttggccga tccgacaccg gatcgaattt ttcttcaaga agaattcgat ccggcgtcgc
     2461 ggctcaacca ggcatgccat cgaactgcgg aagatcgagc ggccttgccc aggccagccg
     2521 gcgccgggtg aacatttcga cccccggctt gatcaactcg ggccggtcga ggctgccgag
     2581 cgtcacgaag acgaggccgg ggaagctctc caggttgctg ctgaataacc tggcgccgca
     2641 atcggggcaa aagttgcggt cgagcccctt gcctgaagcg gcgatgtaat gaaacgcttt
     2701 cgggctgccg ctgatcacgg tgaaatcttc ctgcggcacg gcgaagaacg tggcggcctc
     2761 gccgcccgtt gccctcttgc agtccaggca atggcagttg gcgacaaagt tcgggtccgt
     2821 gtcgaaggca aatcttactg cgccgcaggc gcattgcccg gtatatttcc tggtcatgtc
     2881 aggtgcctcc catcccgtgt tcgaacgtcg tgcgattggc tctccaccgc ctcagggcgc
     2941 cgtgcgtcct ttcggacgca caaaagacgc cctaactctt tcaatccgcg catcagcccg
     3001 acaagcgatt ccgattttcg ggccgatgcg ctggtgccgc agaggtcgtc gaaacgcgcc
     3061 tgcggccggc gtcggcacaa gccgaatgag gagatctcgc cacccgggca gcaatcgtgc
     3121 ccaggggctg aagtgcttaa gccgcggcct tttttcccaa ggcatcaagc agcgtgcggg
     3181 cgccctgttt tgacgaagcc gggttttggc cggtgatcag caggccgtcc tggacgacat
     3241 gcacgcccca atccgcggtc ttcgaaaact ttgcgccctg ctctttcagg acgtcttcga
     3301 gcaggtaggg aacgacctcg accaggtgca tggcctcttc ttcggaatcg gtgaaccccg
     3361 tgacggcccg gcccttggcg atgggctttc catccggcgc tttcacattc gtcaggatac
     3421 cgggtgcgtg gcacacgagc gccacgggtt ttcccgccga aagcatatcc tcgataagcg
     3481 acagcgcatt gcgatcgttc gtcagatccc aaagcgggcc gtgcccgccc gggaagaaca
     3541 cgctgtcata gtctgcctgg tcgatttcag gaagcttgat ggtgtttgcg agcgcagcca
     3601 ttgcggccgc gtctcgttca aaccgtctcg tatcttccgt ctggaacgcc ggctcattgc
     3661 tcttcggatc gagcggaggc tggccgccct tcggcgaagc gagtgtaata tcgaccccgg
     3721 cgtcgcggaa aacgaaataa ggagcagcaa gctcctcgag ccagaatccc gtcttcttgc
     3781 cggtgtttcc caactgatca tgcgatgtga gaaccatgag aattttcatt gctcagctcc
     3841 ttcaagccgg ccggcggaca acgccgtcgg cacccggatt tacggtgaat actgcctgca
     3901 gatctcatgc tgaaacggga gaggacatag agcggctgcg ctgcgaaaca agctctcccg
     3961 cgcagcgttt gctagaattg ctttagccga agcctaacca gacaaacgga ggtcgcgcgc
     4021 gacatccgtt tgtctgggct gagccgacca agacccgcgc tggaaaagcg cagcgtgaga
     4081 ccccgggctg accggctcgt gctggaattt cccgcactag tcgacatgcc ggcggtcaca
     4141 aaaccgccgc tcaatcgtca gcaaatcgcc ccgttaccgc cgcaccgtgc cctcttcaag
     4201 gttccatcgt cgcgacctcg ccggcctttg agcggctgag cgatcgaccg aggcggtctt
     4261 gctgccgatc aaatcatgca cttgaagagg aatgaatatg atcaatcgtt acacatctgt
     4321 cgcaacattg agcactgtgg tcttcagtct gcttgctttc agcccggcat ccgctgtcga
     4381 catggcccag gcgcaacagc agccggcaca ggcgcagccg ccggctcagg gccagacgcc
     4441 gatgcaggga cagcccggcg gcaccggcgc gacagcagcc gtcagcgatc agaaaatcga
     4501 ggccttcgcc gttgcctatc tgcaggtcga caaggtgagg caggaatatt cggccaagat
     4561 cggcgcgacg aaggacgaga ctgccaagca acaactgcag gaggaggcca agaagcagat
     4621 ggtcgacacc gtcaaggctt ctcccgacat ctccgtcgaa gaatactcgt cgatcctgac
     4681 ggccgcccag agcgacccgg ctttggccaa gaaagttctg gaaaaaatcg gcacgccacc
     4741 gccgggccaa cggcagcagc agcagcaata ggctgcgcgc ggcgctgtaa gtcgccacgg
     4801 acgtcttgcc gttcacgccg gaagcagtgc ccgccattcg acgggctctg ctttccacct
     4861 aagaagtcga cgaaatgatc ggctaaaaca ggatgatatt aggccgggtc ggcctaatat
     4921 ctgaatcctg ttctacatca tgtagtgaga gcatgatttc gtccgaaaac cgctcacact
     4981 tttcggcatc atgctttcgt tcagtattgc gagccgctct tgttgttcag gtcgtgccgt
     5041 tcggtgcccg tcagcggcgg gttgaagatg ctgaccagaa tgagatcctg atccttgccg
     5101 ccccgcagat aatggcggtc atgcttgtcc agcacataga tatcaccggc gcggatcgga
     5161 aagacgttgc cgtccatatc ctccacttcg ccctcgccct tgatgcaata gcaggcctcc
     5221 agatgattgc ggtactgaag cagggcttcg ctattggcgc gaacgacggt atggcacacc
     5281 gtaaagccca tgccgtcgtc tttggtcagc aagcggtggc tcgtgccgtt gccccagtcg
     5341 acgaaacgct cggtgagctc cacctccttc agatttctga cgaacatcgc cgattctcct
     5401 gataaattat tgaagatgca gcgatgattc ttttttatcg ctcacgacaa ttagctattg
     5461 aaatggctgg cattttcaaa tgatgattct tgcgtcatct gtgaggaaat tttacaaatg
     5521 caattgccgc cgttgaacgc cctgcgcgct ttcgaagcca cggcccgcct gatgagcctt
     5581 tcgaaagcgg gcgacgagct gcacgttacc catgcggcga tcagccatca gatcaagcat
     5641 ctggagacct ggctcggccg caagctgttg cagaaatcgg gccgcggtgt cgcgctgacc
     5701 gcagccggcg gcgaatatta ccgcgccgtg tcaggatcgc tggcggcgat cgcgcatgcg
     5761 accggcaaca tgcggcgcga tcacaacatg cgggccatca ccgtcggctg cattccctcg
     5821 atcgcctccc gctggctcgt cccggccctg ccctccttcc aggagagcga ccccgatctc
     5881 gacgtcagga tcgtctatgc acgcgccgaa gaacgcttcg acgacgaaag cctggacgtg
     5941 ctgatcacca tgggcgagga tctgagcggc ggcagggaaa gccgcctgct cttctcccgc
     6001 cgcaaccagc ccgtcgccag cggccattac cttgccaaac gaaactggac gatcgacgac
     6061 gtctcgctcg ccggcgccga tctgctgcac gacgaatccg ccgacggctg gaaggaatgg
     6121 ttccgcaagg ccggccagaa agcgccggag ccgctccggg gtccgatatt ccaggatttc
     6181 aacatgctgg cgacggccgt agtcgccggc catggcgtgg cgctctgccc tgtcgaggtg
     6241 ttccgccgcg agatcgaatg cggcgatctg ctggtgcttt ccgacatcgc gacggcagaa
     6301 aaccaaggct attacgtcat atcgaacagc tgggcgaaaa agccggtgcg ccgctttatc
     6361 gactggttca tgacggagtg cggatcgggc gcgtgagatc ccctgcccgc aatttatcga
     6421 agggtcgccg ccgagacgat ggatgcaaat gggtcgcgaa aataaagatg tggcataagc
     6481 ccatccgtga gcgagttggg ccgaggttgg ggattgttaa tcagaaatgc ctaatgtaaa
     6541 tcttggcgtg cacaagttgt gtgggagcta atttgctaca atatctggtt atgacatgag
     6601 actaaggagg gcctcggaca tgcagaaaat tcgtgcggcc ccctcggcgc tcggacaaac
     6661 agaggcgaga gcttcgagct cgatcgaccg gcttttgttc tttgaccgcg atttcaatcc
     6721 cgtcgagaat ttgctgggca ctgagctgcc tgattctgtc aaaccagcag cgtcgttttg
     6781 ggaacatttt ccagaattgg acaaatcggc gattacactc gccctccgtt cattgggcga
     6841 cagtgcccag cctttgcaaa tatcggggga ttttggcgcg ccggcgtcgc acggactgac
     6901 gatctatcgg atcggagatc tgtttgccgt ggttcggtcc gaggaatcta tcgacgatga
     6961 gcgggcgacc cttttgcatc tggccaccca cgatccgctc actggactgc cgaaccgacg
     7021 ccagttcagc gaggacctcg ctgtgttgtt acgggagacc gcaggctcga acgagactct
     7081 gtccctgatg caactcgatc ttgacgattt caaacccgtt aacgacacgc ttgggcatcc
     7141 ggccggcgac aagctccttc agcttgctgc aagccgcatt caagagtgcc ttaccagcga
     7201 cgacagagcc tatcgactgg cgggtgacga attcaccgtc atatcaaggg gcccgggaca
     7261 tcccgccaaa ggacaccagc tagcagaagc tttggttgat gcattcaaaa agcccttcac
     7321 gatagatggc atcgcgctat ttgtgggtgc cagcatcggc atatctgctg ctccaccgga
     7381 cggtacaaat ccggagcagc tgatgaaggc gtccgacgtc gcactctacg ccgcgaagaa
     7441 agacggacgc ggtcgcgcaa gaccgtttga tccctcaatg cttgagttgc tggaacaacg
     7501 cgaactgctg cgccgcagcc ttcgcatggc cctggtccaa caacaattct ctatcgagta
     7561 ccaacccatc gccgagggcg gcagcattgt cggcttcgaa gccttgctca gatggaacca
     7621 ccctctactt ggaaaaatcc caccaacggc atttattccg atggccgagg ccgatggaat
     7681 catgccggaa ataggtgcat gggttttgga gcaggcatgt cgcgaggcaa tgaagtggcc
     7741 gcagaactac gtcgtcgcgg tcaatgtgtc cgcggctgaa ttcttgacaa gcggcctcac
     7801 tgatcgggta tcccaaacgc tagacctgat cgggttgccg cccgaccgtc tggagcttga
     7861 gataaccgaa agcgtgctcc ttgagcggac cgtcaacaat atcgacaccc tgaatactct
     7921 caacgtgcta gggatacgaa tctcgctcga tgatttcggg acagaatatt cttccttgag
     7981 ctatctgaag acattccctt tcgacacgat caaaatcgac aaatacttta tcaccgacct
     8041 cgaaagcgat ctgaaaggcc aggcaatcgt ccgctgcatc gttaacctcg cccatgacct
     8101 cgacatgcag gtgacagccg aaggggttga gacaccaggt caggcggaat ggttgcgcgg
     8161 tgtgggctgc gatagacttc aaggctattt gattagcagg ccgcttccgg tcgaggcgat
     8221 tggcgagttc atcacccggg cggaaacatc cgtaagaccc gcgctaccac agtgaacaac
     8281 cgattttcgc cgcgccttta gctatcgcgt gcatcaacct gacgccccag gcaaacgaaa
     8341 ggagggtgta ttggaacagg aagcagctag cttcgatgac catgcatttg cgccgatggt
     8401 atcgctggaa ctgaacgttg cgatgttcaa atcccgatgg cagttttgcg acaggattac
     8461 cgaatacctc tcagacattc tcggccaagg tcacagcgat cccgctcgat attccaattt
     8521 tctttccgtc gcgacgaatg agctcattga acttgctttc cgttcaacga gcgagccagg
     8581 aaggataagt ttcagtctct atcggagcgc gacagtcaat cggctgagaa ttgtgtttcc
     8641 cggcgaggaa gcatttggcc gaaagcacgc aaatgcaaga tcaagtgaac gccagccggt
     8701 ccccggcgcc ggctctggat acttggtgat gaagtccgac gggacggttt tgctcagcga
     8761 tttggcagca atattccgcg cgacgatccg gattgagata gacggcggac aagggataca
     8821 gatcattgcg gatttcccct cggccgagga cttccgatga gcctgctccc gcagcccttc
     8881 accgttcatt ttgatccgac aaatcaggag ctgttgctgt ctggcaagat gcgaccggaa
     8941 agcgcgactg agattgccga tgccctcaag gtggtgcagc aaagtttgga aaaatacagc
     9001 gggatcgttt acctcaatgt caaacgtctg acgcacatta acatgactgc cttcgtaacc
     9061 ctgtccgatg tcctcgcggc aagctgtcgg accaggccag aacggaagat tgtcatcatc
     9121 acgtcgagcg tggtggcatg gtcgacctct ttgttcgaga cgctggcggc atcacaacca
     9181 aacttgtcgg ttgaagtcta cgattcggca ttttatccgg gccagagctt tgtcgaggac
     9241 gagactttca tccccattct gcgcacccag acgaaaatga catggaggca cgaacgtgaa
     9301 ctgttgcctc gccacggcct gcgcagcggt cttgtcatcg cggatatctg ttgcggaatt
     9361 ggtgatttcg cggccttggt tcagagggaa tttaaaccgg cacgccttgt cgcgctggat
     9421 cattccgtgc gcagcctcga atatgcgcgc agggtcgctg tcgacttcga tctacaggga
     9481 atcgagtaca cctatggtga cgcctcccaa atgctgctgc gagacaatca atttgacttt
     9541 gtgacctgcc gacattcgct gcagattttc aaccgtcccg agatgctgct gcgggagctc
     9601 taccgcatct gtaagcctgg cggccgtgtc tacatcacga acgaaaaaaa ttcgcattgt
     9661 ctcggcgaac cacatgctga aacaataaga tggacttacg aggaagtcgc caaattgttc
     9721 aggtatttcg acatggatgt cgagatgggg ccgaaaagcc gccatctcct cgccgacgcg
     9781 gggttcgata gtatcaaggt cgattccttt atggtcacga accttgacgg ggacccccaa
     9841 gacttcgcgg acatcatcga agcttgggaa aatgtctatg cgggtgagat ggccgttcga
     9901 cggggcgact cgttggattt tattcgcagg ttccggcagg gattcaaaga tcatgtcttt
     9961 gctgctcttc accccaaggg ttatgcaggc tggccgatct gggcagcctc cggccgaaag
    10021 ccgctatgat ggacgagaga tcattgaaga gaccgacaag actaggctca tttcgggcaa
    10081 aattcatcct ggtcgtcggt ggagcagttc tctttgactt gctggtcagc ggcgggctgg
    10141 cactttggaa cgttcagagg ctgtcgcgcg acgcaaccct cgaagtcgga cagggccttg
    10201 aagcggcaaa ccaggaatac attcgtacat atgctgattc caccgcagcc caggtgagtt
    10261 tgctcctgcg gcaggttcat aacgacgtca gcaccttggc aggtgtgctc caggcgcaga
    10321 tcgacgatcc cgagcgtaat tccgacgttg gcgcggcgat cgctcgcaca tcgcccagca
    10381 gcgtcag
//
