LOCUS       NC_003080.1            10159 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_003080.1 Corynebacterium jeikeium K411 plasmid pKW4, complete
            sequence.
ACCESSION   NC_003080
VERSION     NC_003080.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:23:07
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3752
            Orig. end    :: 13911
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10159
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[8752:8911](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5159)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10159
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10159
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(416..874)
                     /locus_tag="ctg2_3"
                     /transl_table=11
                     /translation="MQPRHLRITSSVCKREYITSALGLLLFAAAFTLLYSLDVLWSREE
                     WFILVCAIIACVDIALSSVAPILKKKTTEVRIDDLSITLTKGILIRTRETIPRSNVTMV
                     VRSVNPFDRRWGHEKVTVKASSTELRLPVLPSGSAVDISRMLGIEFER"
     PFAM_domain     complement(476..661)
                     /aSDomain="bPH_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03703.16"
                     /description="Bacterial PH domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_3_0001"
                     /evalue="1.70E-06"
                     /label="ctg2_3"
                     /locus_tag="ctg2_3"
                     /protein_end="133"
                     /protein_start="71"
                     /score="28.2"
                     /tool="antismash"
                     /translation="TTEVRIDDLSITLTKGILIRTRETIPRSNVTMVVRSVNPFDRRWG
                     HEKVTVKASSTELRLPV"
     CDS             complement(883..1788)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 172.3; E-value:
                     2.2e-52)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MTKVVETRAVKKTFRGTGNVLNGVDLHVNESEVVGLLGPNGSGKS
                     TLLKIMVGLLAADGGKVTFWGKGYDNLESPVNRIGVLLSPEWVDERLTVEDFVTSQLIL
                     IKIQSSSRKKICKEILREVGLSGSEKRKISQLSLGMRQRVCLACCFASNPDVLILDEPL
                     NGLDADGVLWVQDLIRSHRDSGGSVLLSSHLMAEMQTVADTIAILNGGKIVARGTIDSL
                     SGERRSLISTDDNPRDLVSVYKNEGYSDVVLDGEKVSVGGISPSEAARLAFSNGFSISG
                     LSETTKSLEEIYRSVVGSRE"
     PFAM_domain     complement(1297..1728)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_4_0002"
                     /evalue="5.30E-31"
                     /label="ctg2_4"
                     /locus_tag="ctg2_4"
                     /protein_end="164"
                     /protein_start="20"
                     /score="108.0"
                     /tool="antismash"
                     /translation="LNGVDLHVNESEVVGLLGPNGSGKSTLLKIMVGLLAADGGKVTFW
                     GKGYDNLESPVNRIGVLLSPEWVDERLTVEDFVTSQLILIKIQSSSRKKICKEILREVG
                     LSGSEKRKISQLSLGMRQRVCLACCFASNPDVLILDEPLN"
     CDS             complement(1785..2528)
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MNTILSRVHTFTHTRVGRFSFAIATIILLAVSLSSAHKVKAGEIA
                     DVSELFSGGNSFALFIVGMGMTIFQASEYNSGGMPYILMRVPNRIEVAKDSLATSAVIS
                     IGYALIANVFTVAVSLAYLTFSGTIQEISYDTSSILLTMIGTIFSYLIVGIIAFTTGDI
                     TQSTAGGVFIYFVIYWVLPLSGALVTAIRGEIGNALVQYSLASNVEKLLTTSGTAFIAS
                     MLIISAWAVLISIVGFAQFRRYSPK"
     CDS             complement(2544..2822)
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MTTLIIICALAAVAGLQYFLPRFGPNILGAVIPILFAVAAVILLM
                     NNGVDRIRDILLPLAGFFALLCIWGGAIEAKKAKTEDEMEKIDRQIS"
     CDS             complement(2825..3103)
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MVTKWIQNLSQSDLALLKNFVVQSGNIKSLSAQYSVSYPTMRARL
                     DTLIEKIKIGDEEPDTFIAQLQAYAIDRKVPSQFVQEIAEIYYTRKE"
     PFAM_domain     complement(2927..3094)
                     /aSDomain="DUF2089"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09862.11"
                     /description="Protein of unknown function (DUF2089)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_7_0003"
                     /evalue="6.80E-11"
                     /label="ctg2_7"
                     /locus_tag="ctg2_7"
                     /protein_end="59"
                     /protein_start="3"
                     /score="42.4"
                     /tool="antismash"
                     /translation="KWIQNLSQSDLALLKNFVVQSGNIKSLSAQYSVSYPTMRARLDTL
                     IEKIKIGDEEP"
     CDS             complement(3710..4507)
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="VTYDYWRPSQEQRDKVNEVASDRRPELLEESYREALAWLEDVDEF
                     SPTPDPAMATILKRALSRVQFYNQTVPDVDLPSPQWTPVDDLVLNGGVAKEWIASLHTV
                     HNIPTANSRDARQVRALLHALGHDVPSFLREQYQVASQGEAGVYCMVPDDRANVLAVRP
                     TSCRYLDTTGASVETHRDPSRGGNLAVFLRLNAGVLTLLPHESRHSGVQFGYSGTGPRN
                     LANDIVNAYPAASTLTDNQRDSETDRVFQEISVDGLTALMIHL"
     CDS             4669..4875
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="VILSMSAIDDPQHLLTRLAAADRLSLQSLLPGKLWVNLRPRLQGV
                     RQYAVDLTGAHETMMSVTAASAA"
     CDS             complement(5001..5159)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIi"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_10"
                     /sec_met_domain="Bacteriocin_IIi (E-value: 2.5e-32,
                     bitscore: 100.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGFLKVVKAVAKYGSKAVKWCWDNKGKILEWLNIGMAVDWIVEQ
                     VRKIVGA"
     PFAM_domain     complement(5004..5159)
                     /aSDomain="Bacteriocin_IIi"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11758.10"
                     /description="Aureocin-like type II bacteriocin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_10_0004"
                     /evalue="2.80E-29"
                     /label="ctg2_10"
                     /locus_tag="ctg2_10"
                     /protein_end="52"
                     /protein_start="0"
                     /score="100.8"
                     /tool="antismash"
                     /translation="MAGFLKVVKAVAKYGSKAVKWCWDNKGKILEWLNIGMAVDWIVEQ
                     VRKIVGA"
     CDS             complement(5638..5946)
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MTTVTRRDPADKAEIDAIEKKLLANPEIAKLIDDLGTSTTDANDL
                     VRGMLQASITRGINAEMDVHLGYEPSDREGKTAAGTDNHRNGIYPKTVDSNYGAGNC"
     PFAM_domain     complement(5653..5835)
                     /aSDomain="Transposase_mut"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00872.20"
                     /description="Transposase, Mutator family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_11_0005"
                     /evalue="4.90E-05"
                     /label="ctg2_11"
                     /locus_tag="ctg2_11"
                     /protein_end="98"
                     /protein_start="37"
                     /score="22.5"
                     /tool="antismash"
                     /translation="STTDANDLVRGMLQASITRGINAEMDVHLGYEPSDREGKTAAGTD
                     NHRNGIYPKTVDSNYG"
     CDS             6238..6843
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MQLFYAGVGRKPRYCSQTCRSRAWEKRRAAREGLISQEVVDRPVE
                     VYKPIDAEQVAQWLSGHPRRLSAVLKLLEWTDEHLEVFRRGLEQSTEELSLIPTAEKER
                     LESASQKAFRFKHDLASWQRRLRTQREENAALRQELEQCKSVKVPTPVAEKRHPAEVAP
                     MPTFSGEAKTVKVEGQQVTVPARWSRKQIRQWMRSNGR"
     CDS             7162..7779
                     /locus_tag="ctg2_13"
                     /transl_table=11
                     /translation="MTNETDLSLPLELNEHQHVVTGQLVGYARVSTTGQNLDRQVAQLQ
                     KAGATEIYKEKISGASRERPQLEEMLRYLRKGDQLIVTSMDRLARSFLDLHNIIDDLIS
                     RGVSVRFLRESQTYSSHSDPVAVLMLGVLGSVAQFERAIMRERQAEGIAQAKKRGAYKG
                     RAPAMNEASIKQAREMIDMGVPKADVARRLGVSRATLYRYLP"
     PFAM_domain     7234..7641
                     /aSDomain="Resolvase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00239.23"
                     /description="Resolvase, N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_13_0006"
                     /evalue="2.50E-40"
                     /label="ctg2_13"
                     /locus_tag="ctg2_13"
                     /protein_end="160"
                     /protein_start="24"
                     /score="138.0"
                     /tool="antismash"
                     /translation="VGYARVSTTGQNLDRQVAQLQKAGATEIYKEKISGASRERPQLEE
                     MLRYLRKGDQLIVTSMDRLARSFLDLHNIIDDLISRGVSVRFLRESQTYSSHSDPVAVL
                     MLGVLGSVAQFERAIMRERQAEGIAQAKKRGA"
     PFAM_domain     7648..7776
                     /aSDomain="HTH_7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02796.17"
                     /description="Helix-turn-helix domain of resolvase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_13_0007"
                     /evalue="4.90E-11"
                     /label="ctg2_13"
                     /locus_tag="ctg2_13"
                     /protein_end="205"
                     /protein_start="162"
                     /score="42.6"
                     /tool="antismash"
                     /translation="GRAPAMNEASIKQAREMIDMGVPKADVARRLGVSRATLYRYLP"
     CDS             8317..9213
                     /locus_tag="ctg2_14"
                     /transl_table=11
                     /translation="MTISLPALSDDDDGQTVDYTNRIFVQALFPYRKSDEYRRAITQGS
                     KEVIISSPNGLPYGKYPRLIMAYIITTAVARAHQVEQGLMDSDEARQIPLGESLNEFFR
                     RIGVVARGTGGSRGTVTRIREQLVRLASSSIVVRSRIKKGRVDIHWGVNHPIAGEWEPW
                     FDADNPDQAAIQLTDRFFQLIADAPIPIDLDILHKLGKPRAMDIYVWITVKKARLNYQN
                     RPSFTFSWKQMEHQFSPKELTTWAQRANFRKEFNGCLETIRALWPDVGVDTDTKAGVTL
                     HKSAPSVTMRPSRKQLR"
     PFAM_domain     8485..9006
                     /aSDomain="RepA_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04796.14"
                     /description="Plasmid encoded RepA protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_14_0008"
                     /evalue="2.00E-38"
                     /label="ctg2_14"
                     /locus_tag="ctg2_14"
                     /protein_end="230"
                     /protein_start="56"
                     /score="132.0"
                     /tool="antismash"
                     /translation="PYGKYPRLIMAYIITTAVARAHQVEQGLMDSDEARQIPLGESLNE
                     FFRRIGVVARGTGGSRGTVTRIREQLVRLASSSIVVRSRIKKGRVDIHWGVNHPIAGEW
                     EPWFDADNPDQAAIQLTDRFFQLIADAPIPIDLDILHKLGKPRAMDIYVWITVKKARLN
                     YQNRPSFTFSW"
     CDS             9250..9477
                     /locus_tag="ctg2_15"
                     /transl_table=11
                     /translation="MSTATWGAARRIAGTLGGRSTVLGSFGASETDRQHLLALVGLDRE
                     VDKAFGAPRKLTTECQRQELLFENYSKLTS"
     CDS             9574..10158
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 49.1; E-value: 9.1e-15)"
                     /gene_kind="other"
                     /locus_tag="ctg2_16"
                     /transl_table=11
                     /translation="MRVSFVHTKGGVGKTTSAIMVAAAATRHGRAVEVFDTDPQGSASR
                     WAEIAEGRGDTLPFPVRYLTANELRQLPADESTLQIVDTPPGEAASIQAAIDTADLVVV
                     PSGASPMDIDRVWPTIETITGHPAGVLLTGVLMHTRFYTEARHLLEDQGVATFYNAIPQ
                     REEIKAAFGTNPIRFHGYDDVYQEISEVEEL"
     PFAM_domain     9583..10083
                     /aSDomain="CbiA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01656.25"
                     /description="CobQ/CobB/MinD/ParA nucleotide binding
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_16_0009"
                     /evalue="4.00E-13"
                     /label="ctg2_16"
                     /locus_tag="ctg2_16"
                     /protein_end="170"
                     /protein_start="3"
                     /score="49.6"
                     /tool="antismash"
                     /translation="SFVHTKGGVGKTTSAIMVAAAATRHGRAVEVFDTDPQGSASRWAE
                     IAEGRGDTLPFPVRYLTANELRQLPADESTLQIVDTPPGEAASIQAAIDTADLVVVPSG
                     ASPMDIDRVWPTIETITGHPAGVLLTGVLMHTRFYTEARHLLEDQGVATFYNAIPQREE
                     IKAA"
ORIGIN
        1 taacagcata ggcattctcc ggagacaaac agcagaaaac agccgtttcc agtgatgaac
       61 ccgcgaagta gacttttagc cgtttgcaac ccagccacct cagaaggaga ttttcttcga
      121 tctcgacacc tgaaacccca gcccatttag aagaaatata cctcttcgaa gatatccctc
      181 ttccgataga aataccggcg tccgttgccc acccagaaat accaactgta gatataagta
      241 tgcggtatac cctggtccag gagtagtaga ccgcagatac tacgagagtg ccgaaccaca
      301 ctccgtccgc tacaaacata aatccaaaca ggatgctata gacggggata gaatttggca
      361 acaaggatac aatctcaagt agtatcccgc gtttactgtt cttcagctcc attggtcatc
      421 tctcgaattc tatgccgagc attctggaaa tatctacggc cgaacctgac ggtagtacgg
      481 ggagccgtaa ctcggtagat gaagctttca cggttacttt ttcatgaccc caccttctgt
      541 cgaaaggatt aaccgacctg acgaccattg tcacgttcga tcggggaata gtctcccgag
      601 tacgaatcaa tatcccctta gttagggtta tggataaatc atcaattcgc acttccgttg
      661 tcttcttctt gaggatagga gcaacagaag acaaagcaat atctacgcat gcaataattg
      721 cgcagactaa tataaaccac tcttccctgg accatagaac atctagagaa tagagtagag
      781 taaatgcggc agcaaacaga agtaaaccca gcgcagaagt aatgtattcg cgcttgcaga
      841 cactcgaagt tatccgtagg tgtcgaggtt gcatacagcc ctctattctc tagaccccac
      901 gactgaccgg taaatctcct ccaggctctt agtcgtctcg gacagcccac tgatagagaa
      961 cccattggag aaagcaagac gagctgcttc tgacggggaa atacccccta ccgatacctt
     1021 ctctccatcc aatacaacgt cagaatatcc ttcattctta tatacagaaa ctagatcacg
     1081 tgggttatcg tctgtggaga tcagggaacg acgctccccg gaaaggctat caattgttcc
     1141 tcgtgccact atttttccgc catttaaaat agcaattgta tccgcaactg tttgcatttc
     1201 ggccatgagg tgtgaagaca agagtaccga gccaccacta tcccgatggg aacgtataag
     1261 atcttgcacc caaagtacgc cgtctgcgtc caatccgtta agcggttcat ccagaatgag
     1321 aacatcaggg ttagatgcaa aacagcatgc caagcacaca cgttgcctca tcccaagtga
     1381 gagttgcgat atttttctct tctcagaacc agaaagtccg acttcccgta gtatttcttt
     1441 gcatatcttc ttacgactgg atgactgtat cttgataagg atgagttgtg aagttacgaa
     1501 gtcttcgaca gtcaatcgct catccaccca ctcgggggat agaagtacgc ctattctatt
     1561 caccggagat tcgaggttat cgtacccttt accccagaac gttacttttc ctccgtcggc
     1621 cgctagaagt cctaccatta tcttcaggag agtagacttg cccgatccgt taggacccag
     1681 caggccgacc acttcggatt cgttgacatg gagatcgacc ccatttaaaa cattcccggt
     1741 cccccggaaa gtctttttta cagctctcgt ctcgactact ttagtcattt cggtgagtac
     1801 ctcctgaact gagcgaagcc aacgattgat atcaacacgg cccatgccga aataataagc
     1861 atgctggcta tgaaagcagt tccacttgta gttaggagct tctctacgtt agacgccaag
     1921 ctatactgca ccagtgcatt tcctatttca ccgcgtatag ctgtaactag tgcgccagat
     1981 agcggaagta cccagtagat gacgaagtat atgaacacgc ccccggcagt actttgtgtt
     2041 atatcgcctg tggtgaaagc gatgatcccg acaatcagat acgagaatat cgtacctatc
     2101 atcgtcagta ggattgaaga agtgtcatag cttatctctt gtatcgttcc gctgaaggtg
     2161 aggtatgcga gcgaaacggc aacggtgaat acgttcgcga tcaatgcgta tccgattgat
     2221 atcactgcgg acgttgccag ggaatctttc gcgacctcga ttctatttgg cactcgcatg
     2281 agtatgtacg gcatacctcc cgagttatac tcagaggcct gaaatatcgt catgcccata
     2341 ccgactatga aaagcgcaaa gctatttccg ccagagaaga gttccgatac atctgctatt
     2401 tcgccggcct tgactttgtg agcactcgat aacgacactg ccagtagtat tattgtggca
     2461 atggcgaatg agaatcggcc cactcttgtg tgtgtgaatg tatgcaccct ggagaggatg
     2521 gtgttcattt atttgtcccc tgtttaactg atttgcctgt cgattttttc catttcatct
     2581 tcagtcttgg ccttttttgc ttcaattgct ccaccccaga tgcagagcaa ggcaaaaaat
     2641 ccagcaagtg gcaggaggat atctcggatc ctgtcaacgc cattgttcat caggagaatt
     2701 acagcggcaa cggcaaatag aataggaatt accgcaccaa gaatgttcgg tccaaatctg
     2761 gggaggaaat actgaagtcc cgctacagct gccaatgcac agatgatgat taatgttgtc
     2821 attttcactc ttttctcgtg tagtaaatct ctgcgatttc ctggacgaat tgcgatggaa
     2881 cctttcgatc tatcgcatag gcctgcagtt gcgcgatgaa cgtatctggt tcttcgtcgc
     2941 cgatttttat cttctcaatt agagtgtcta gccgtgctct cattgtggga tacgacacgg
     3001 agtattgagc ggagagcgat tttatattgc cggactgaac gacgaaattc ttcagtaagg
     3061 caagatcgct ttgggagagg ttttgaatcc acttagttac catctttttt caatccaggt
     3121 gtgactggtg tgtttgcgtt caggttagct ttgttgagct atttagtttt ggacgatatc
     3181 acgttggcgc gacaccctcg tgaggtaaat ttcagctacc ccattctgga tatttctcat
     3241 cttgacatag tgtccctagc ggctttgtga actgcatgtt tgcttccact ttcttaactg
     3301 tgatgtgggt cacactatgg tagcgttacc cccatttcgg tctacttctt tcgcggagtt
     3361 accacctcct acactcccga ttccatacct ggagcttccc atcatttacg tcactgtgac
     3421 gtattcggct cgcacctcct taggtatcgc cgctgtcgcg gagagcatcg ttttcccttt
     3481 gcggagcacc tactaatggt ttcggcccca ggggctaggc cgtgttgcta aaggggctga
     3541 cttcatccag ttcaccgtcg ccgccaagcg caccccaggg tgaagagcct ttaaacattg
     3601 tttatatgag ttcaggacgg gcacgacagt ccttcgctgg tggtgcggtt caggcaccgt
     3661 cgccgagcag ccacgactcc aggtccccag tgctgaaacc ggcccagagc tataggtgga
     3721 tcatcagggc ggtgaggccg tcgacggaga tctcctgaaa gaccctgtct gtctcactgt
     3781 cccgttggtt gtccgtcagg gtactggcgg ctgggtacgc gttgacgatg tcgttggcga
     3841 ggtttctggg gccggtgccg ctgtaaccga actgcacgcc gctgtgtcga gactcgtgtg
     3901 ggagaagggt caacaccccg gcgttcagcc ggaggaagac ggccaggttg ccccctcggc
     3961 tcggatcgcg gtgtgtctcc acactggccc cggtggtatc caaatagcgg cagctcgtcg
     4021 ggcgtaccgc caagacgttg gcacgatcgt cagggaccat gcagtacact ccggcctcgc
     4081 cctgggaggc cacctggtac tgctcacgca ggaacgacgg cacatcgtgt ccgagggcgt
     4141 gcagaagcgc ccggacctga cgagcatccc gactgttggc tgtaggaata ttgtgcacag
     4201 tgtgcaggct ggcgatccac tccttcgcta ccccaccgtt gaggacgaga tcgtcgacgg
     4261 gggtccactg aggtgatgga agatccacgt ccgggacggt ttggttgtag aactgcaccc
     4321 tgctcaacgc ccgcttgagg attgtggcca tcgccggatc cggtgtgggg ctgaattcgt
     4381 caacgtcctc aagccaggcc aacgcttccc tatacgactc ctcgagcaat tcgggtcggc
     4441 gatcactggc aacttcattg accttgtccc gttgctcctg cgacggtcgc cagtagtcgt
     4501 acgtcacggc tatgcgttcc ttcagtcacg gcgggtagag agacagtgga gagtggtcga
     4561 tcagattgaa catcccactg acctcatggg cgagctgggt agcgaactgc gcccgcagcg
     4621 gctcatgctc ctggttgatc tgcgagagcg gccgaccgag gggccgtagt gatcctcagc
     4681 atgtccgcga tcgatgaccc acagcacctg ctgacgagac tggccgccgc tgatcgcctg
     4741 tcgctacaat cgctcctgcc ggggaagctc tgggttaacc tccggccacg tctccagggg
     4801 gtgagacagt acgcggtcga cctcaccggt gcgcacgaga cgatgatgag cgtcacggcc
     4861 gcgtccgcgg cgtgactact tgttgtcacc taatcgtgca tcaaacccgt atggcgaaca
     4921 tattcttcca gcggacatgc aacataaaaa cataaaagtg cgcccgagct tacgctcggg
     4981 cgcacttccg aagatgaagg ctaggcgcca acaatcttac gaacctgctc gacgatccag
     5041 tccacagcca taccgatgtt cagccactcc aggatctttc ccttgttgtc ccagcaccac
     5101 ttcacagcct tggaaccata cttcgcaaca gccttaacga ccttcagaaa accagccatc
     5161 ttaaatcttt cctttctgac acgccacctg ggacgatttg aaaaatttcc tcatttcctt
     5221 tccctaacta cactagcttc aaaatctccc gagacaacag gaaggagcga caaatcaata
     5281 gatgaaaact tttctttcac aatgtatgaa agaaattcat caccgctttc gcaaagttaa
     5341 acgccactgc aagcgtaggg tcctgaacta cccccatgtg gggtattgtc gaatgcgtgc
     5401 agcacagtga acgcaggcaa ggtacggacc gagccgagag gcagcacctc cccgaggctt
     5461 gagcacgcag agaaacctta tcggcaaccc aaatcagtcc gattacctat agctattcgg
     5521 gggatatggt tccccacgct ccgaagcgcc gctgcgtaac gccctcactg cctgatgcag
     5581 gttccagcag acagaaccac tcgcaggtat cggccaagcc aacgatcgcg tgggacatca
     5641 acagttaccg gccccgtagt tagagtccac ggttttcggg tagatgccgt tgcggtgatt
     5701 gtctgttcca gctgcagttt taccctccct atcgctgggc tcgtagccaa ggtggacatc
     5761 catttcagcg ttgattcccc tggtaatcga ggcttgcaac atgccccgaa ccaggtcgtt
     5821 tgcatccgtc gtagacgtgc ctaggtcatc aatcagtttc gcgatttcgg ggttagcaag
     5881 cagcttcttt tcaatcgcgt caatctcggc cttatcggcc ggatctcgtc tcgtcacagt
     5941 agtcattctg gtccatctcc tcatgcaggt tgggtaccca cacacaaacc atcagacact
     6001 ctccatcgtg ggcagcgcta caccccaccc cagcctgtta gacgctcgcg cagatcgata
     6061 gcagcgcatc cacctgggca tttgcccgtg tcgctatcgc tacgggcagt cgcccttcaa
     6121 attcactcac accgtttgca catcatgtgt gtcgggttac gttgtgacga aatgggttag
     6181 tgtggaggca tggataaccc cttagaatcc acgcgcctgc actgcgttga gtgcggtatg
     6241 caattgttct acgcgggagt gggacgcaag ccgcgctact gtagccaaac ctgtcgcagc
     6301 cgagcgtggg aaaaacgccg tgcagcccgc gaagggttga tttcccagga ggtcgtggat
     6361 cgtcccgtag aggtctacaa acccatcgac gcagagcagg tagcccagtg gctaagcggg
     6421 cacccgcgac ggctatctgc ggtgctgaaa ctcttggagt ggacagacga acatcttgag
     6481 gtatttcgca gaggattaga gcaaagcacc gaagagttaa gcctgattcc tacggcggaa
     6541 aaagaacgac tcgagtctgc ctcgcagaag gcatttcgct tcaaacatga ccttgcttct
     6601 tggcaacgtc gtctgcgtac gcagcgagag gaaaacgccg cgctgaggca agaactcgag
     6661 caatgcaaaa gcgtgaaagt ccccacgccc gttgcagaaa agcggcaccc tgctgaggtg
     6721 gcaccaatgc ctacgtttag cggtgaggct aagaccgtca aagttgaagg ccaacaggtc
     6781 actgttccgg ctcgctggag tcggaaacag attcgtcaat ggatgcggag taatggacgg
     6841 taaactcggt aaaaaaattg acctgttttg tcacaacgta acccgacaca catgatgtgc
     6901 aaaaggtgtg cgtggatttg gagggctagt gcccgtagcg agttcgatac gggcaaatat
     6961 ccaggtggat gtactgctat tgatctgtgt gagcggctag caggctgggg tggggtgtag
     7021 cgctgcccgc aatgtatgtg aggataaatc tgcgcagtct gacctacgca aacacgaact
     7081 tctcgcaaga gtgtcttttt agggcatgcc aaatgagaca ctttcgagtt acagggaaag
     7141 ctgttgcttt agggttggtt tatgaccaat gagacagatc tgtcgctacc gcttgagcta
     7201 aatgaacatc agcatgtcgt cactggacag ttggtggggt acgcccgtgt aagcacgacg
     7261 ggtcagaatt tggatcgtca ggtcgctcag ctccaaaagg cgggggcgac cgagatctac
     7321 aaggagaaga tcagtggcgc gtcccgtgag aggccgcaac tggaggagat gctgcgctat
     7381 ctgcgtaagg gggatcaact gatcgtcacg agcatggatc ggctggcgcg gtctttcctc
     7441 gacctgcaca acatcattga tgacctcatt agtcggggag tgtccgtgcg gtttctgcgg
     7501 gagtcgcaga cctactcgtc tcacagtgac ccggtggccg tgttgatgct cggtgtcctg
     7561 gggagcgttg cgcagttcga gcgggcgatc atgcgagagc gtcaggctga ggggatcgcg
     7621 caggcgaaga agcgcggcgc atacaaggga agggcgccgg cgatgaacga ggccagcatt
     7681 aagcaggcgc gagaaatgat cgatatggga gtacccaaag cagacgttgc tcgccgtctt
     7741 ggtgtgagta gagcgactct ttatcggtat ctcccttagt cttcatgagg gtaaatctgc
     7801 gcagcctggc aacgctattg ctgaccaggc acgccagagg tagcagacag tacgcattca
     7861 ccatcgagcg ccagcgtcaa gagccactgt ttgagaacta ctccaagcta acgtcataac
     7921 gctataacgc taacgttatg acgttgcgac gctagaacgc tagaacgtga taacgttgta
     7981 cgcaggtaga cggcaacaaa aatgaatggt gatacatgag agtatcgttc gtcccctcgg
     8041 gtgcatcccc cgagtgtgtg gccaacgata gaaaccatta ctggccaccc cgccggcgtg
     8101 ttgcttaccg gtgtacttat gcacacccgg ttcgagtccg gggtgcgcac cttctcttaa
     8161 atagggaaat agggaaaacc ccgcaccgta gaggcggcaa cctctagcgg gggtttgaag
     8221 cgagactttc cggccctcgt tgttggatgt atctcattag gacgcgatat acagcaacgg
     8281 ctgaaaacct tcgtacagat aaaggagtac ctatccatga caatcagcct tcccgcccta
     8341 tctgacgacg atgacggtca gactgtcgac tacacgaacc ggattttcgt ccaagcactg
     8401 ttcccctacc gcaaaagcga cgagtaccgg cgcgcaatca cgcagggcag caaagaagtc
     8461 atcatcagct cccccaacgg gttgccttac ggtaagtacc ctcggctaat catggcctac
     8521 atcatcacta ctgccgtcgc gcgagcgcac caagtcgagc aagggcttat ggatagcgat
     8581 gaagcgcgtc agattcccct cggggagtct ctcaacgagt tcttccggcg cataggtgtt
     8641 gttgcacgcg ggacgggcgg atcacgtggc actgtcaccc gtatccgcga gcagctggtt
     8701 cgccttgctt catcctccat tgtcgtccga agtcgtatca aaaaaggccg cgtggacatt
     8761 cattggggcg taaaccaccc catcgctggc gaatgggagc cgtggtttga cgcagacaat
     8821 cccgatcaag cggctatcca actcactgat aggttcttcc agctcatagc tgacgctccg
     8881 attcctattg atctcgacat cctgcacaag ctgggcaagc cacgggcaat ggacatctat
     8941 gtgtggatca ctgtcaaaaa agccaggctc aattatcaga accggcctag cttcacgttc
     9001 tcctggaagc agatggaaca ccagttctcc cccaaagaac tgacaacctg ggcacagcga
     9061 gctaacttcc gcaaggagtt caacgggtgc ctagaaacaa tccgtgccct atggcctgac
     9121 gttggtgtgg acacggacac taaggctggc gtaacccttc acaagagcgc cccgtctgta
     9181 accatgcgac catcgcggaa acaactccgc tagtccactt tcgatacacc ccacaccgcg
     9241 tcttcatcca tgtccacggc cacgtggggc gctgcacgtc ggattgccgg cactctcggc
     9301 gggcgtagta ccgtcctcgg ctcgtttgga gccagcgaga ccgaccggca gcaccttctt
     9361 gccctcgtag gccttgaccg tgaagttgat aaagcattcg gtgcaccacg gaagctcaca
     9421 acggagtgcc agcgccaaga gctactgttc gagaactact ccaagctaac gtcataacgc
     9481 tataacgcta acgctatgac gttgcgacgc tatggcgcta gaacgtgata acgttgtatg
     9541 caggtagacg gcaacaaaaa ggaatggtga tacatgagag tatcgttcgt ccacaccaaa
     9601 ggaggtgtag gaaaaacgac tagcgcgatc atggttgcag cagcagcaac ccgccatggg
     9661 cgcgcagtgg aagtgttcga cactgatccg caaggatcag cctcgcggtg ggcagagatc
     9721 gccgaagggc gcggtgatac cctcccgttc cccgttcgct acctgactgc caacgagcta
     9781 cggcagctac ccgcagacga atccactctt cagattgtcg ataccccgcc cggcgaagca
     9841 gcatccattc aagccgctat cgataccgcc gatctagtag tcgtcccctc gggtgcatcc
     9901 ccgatggata ttgaccgtgt gtggccaacg atagaaacca ttactggcca ccccgccggc
     9961 gtgttgctca ccggtgtgct tatgcacacc cggttctaca ccgaagcacg ccaccttctc
    10021 gaagaccaag gggtagccac cttttacaat gcgatccccc aacgcgagga aattaaagcg
    10081 gcgttcggca ctaaccccat ccgctttcat ggctacgacg atgtgtacca agagatctcc
    10141 gaagttgagg aactgtaat
//
