GCF_003148495.1_ASM314849v1_genomic - 12 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_QGGH01000001 (original name was: NZ_QGGH01000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NAPAA	1,413,342	1,451,573

NZ_QGGH01000004 (original name was: NZ_QGGH01000004.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	NRPS	74,840	121,121	9-methylstreptimidone	Polyketide:Modular type I	6%
Region 4.2	lassopeptide	163,069	185,512	salecan	Saccharide	12%
Region 4.3	RRE-containing	190,099	210,383	salecan	Saccharide	18%
Region 4.4	hserlactone	486,047	506,685

NZ_QGGH01000005 (original name was: NZ_QGGH01000005.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	RRE-containing	2,753	23,181

NZ_QGGH01000007 (original name was: NZ_QGGH01000007.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	terpene	234,629	255,528

NZ_QGGH01000009 (original name was: NZ_QGGH01000009.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 9.1	T3PKS	53,428	94,369

NZ_QGGH01000013 (original name was: NZ_QGGH01000013.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 13.1	hserlactone	111,579	132,247

NZ_QGGH01000015 (original name was: NZ_QGGH01000015.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	phosphonate	45,129	86,037

NZ_QGGH01000016 (original name was: NZ_QGGH01000016.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	hserlactone	67,997	88,641

NZ_QGGH01000031 (original name was: NZ_QGGH01000031.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 31.1	hserlactone	1	11,187

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	NAPAA	1,413,342	1,451,573
Region 4.1	NRPS	74,840	121,121	9-methylstreptimidone	Polyketide:Modular type I	6%
Region 4.2	lassopeptide	163,069	185,512	salecan	Saccharide	12%
Region 4.3	RRE-containing	190,099	210,383	salecan	Saccharide	18%
Region 4.4	hserlactone	486,047	506,685
Region 5.1	RRE-containing	2,753	23,181
Region 7.1	terpene	234,629	255,528
Region 9.1	T3PKS	53,428	94,369
Region 13.1	hserlactone	111,579	132,247
Region 15.1	phosphonate	45,129	86,037
Region 16.1	hserlactone	67,997	88,641
Region 31.1	hserlactone	1	11,187

No secondary metabolite regions were found in these records:: NZ_QGGH01000002 (original name was: NZ_QGGH01000002.1); NZ_QGGH01000003 (original name was: NZ_QGGH01000003.1); NZ_QGGH01000006 (original name was: NZ_QGGH01000006.1); NZ_QGGH01000008 (original name was: NZ_QGGH01000008.1); NZ_QGGH01000010 (original name was: NZ_QGGH01000010.1); NZ_QGGH01000011 (original name was: NZ_QGGH01000011.1); NZ_QGGH01000012 (original name was: NZ_QGGH01000012.1); NZ_QGGH01000014 (original name was: NZ_QGGH01000014.1); NZ_QGGH01000017 (original name was: NZ_QGGH01000017.1); NZ_QGGH01000018 (original name was: NZ_QGGH01000018.1); NZ_QGGH01000019 (original name was: NZ_QGGH01000019.1); NZ_QGGH01000020 (original name was: NZ_QGGH01000020.1); NZ_QGGH01000021 (original name was: NZ_QGGH01000021.1); NZ_QGGH01000022 (original name was: NZ_QGGH01000022.1); NZ_QGGH01000023 (original name was: NZ_QGGH01000023.1); NZ_QGGH01000024 (original name was: NZ_QGGH01000024.1); NZ_QGGH01000025 (original name was: NZ_QGGH01000025.1); NZ_QGGH01000026 (original name was: NZ_QGGH01000026.1); NZ_QGGH01000027 (original name was: NZ_QGGH01000027.1); NZ_QGGH01000028 (original name was: NZ_QGGH01000028.1); NZ_QGGH01000029 (original name was: NZ_QGGH01000029.1); NZ_QGGH01000030 (original name was: NZ_QGGH01000030.1); NZ_QGGH01000032 (original name was: NZ_QGGH01000032.1); NZ_QGGH01000033 (original name was: NZ_QGGH01000033.1); NZ_QGGH01000034 (original name was: NZ_QGGH01000034.1); NZ_QGGH01000035 (original name was: NZ_QGGH01000035.1); NZ_QGGH01000036 (original name was: NZ_QGGH01000036.1); NZ_QGGH01000037 (original name was: NZ_QGGH01000037.1); NZ_QGGH01000038 (original name was: NZ_QGGH01000038.1); NZ_QGGH01000039 (original name was: NZ_QGGH01000039.1); NZ_QGGH01000040 (original name was: NZ_QGGH01000040.1); NZ_QGGH01000041 (original name was: NZ_QGGH01000041.1); NZ_QGGH01000042 (original name was: NZ_QGGH01000042.1); NZ_QGGH01000043 (original name was: NZ_QGGH01000043.1); NZ_QGGH01000044 (original name was: NZ_QGGH01000044.1); NZ_QGGH01000045 (original name was: NZ_QGGH01000045.1); NZ_QGGH01000046 (original name was: NZ_QGGH01000046.1); NZ_QGGH01000047 (original name was: NZ_QGGH01000047.1); NZ_QGGH01000048 (original name was: NZ_QGGH01000048.1); NZ_QGGH01000049 (original name was: NZ_QGGH01000049.1); NZ_QGGH01000050 (original name was: NZ_QGGH01000050.1); NZ_QGGH01000051 (original name was: NZ_QGGH01000051.1); NZ_QGGH01000052 (original name was: NZ_QGGH01000052.1)

Compact view

c00001_NZ_QGGH.. - Region 1 - NAPAA

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Location: 1,413,342 - 1,451,573 nt. (total: 38,232 nt) Show pHMM detection rules used

NAPAA: (AMP-binding and PP-binding and TIGR02353)

Legend:

core biosynthetic genes

additional biosynthetic genes

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000231.1	0.24	Polyketide	griseusin	Streptomyces griseus
BGC0001197.1	0.23	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000228.1	0.22	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000234.1	0.22	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001444.1	0.22	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0000427.1	0.22	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001538.1	0.20	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0002008.1	0.20	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000204.1	0.20	Polyketide	benastatin A, benastatin B, BE-43767, TAN1532B	Streptomyces sp. A2991200
BGC0000343.1	0.20	NRP	enterobactin	Pseudomonas sp. J465

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000231.1	0.57	Polyketide	griseusin	Streptomyces griseus
BGC0001197.1	0.56	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000228.1	0.55	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000234.1	0.55	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001444.1	0.55	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0000427.1	0.54	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001538.1	0.53	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0002008.1	0.53	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000204.1	0.52	Polyketide	benastatin A, benastatin B, BE-43767, TAN1532B	Streptomyces sp. A2991200
BGC0000343.1	0.52	NRP	enterobactin	Pseudomonas sp. J465

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 1413341 - 1451573:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1435

Search NORINE for peptide: strict or relaxed

AMP-binding (48..448): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ayyasAHmMK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 40% (weak)

ctg1_1439

Search NORINE for peptide: strict or relaxed

AMP-binding (61..458): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DFEaLgtVtK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 60% (weak)

c00004_NZ_QGGH.. - Region 1 - NRPS

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Location: 74,840 - 121,121 nt. (total: 46,282 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.34	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.32	NRP	indigoidine	Streptomyces chromofuscus
BGC0000457.1	0.32	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000900.1	0.32	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.31	NRP	dimethylcoprogen	Alternaria alternata
BGC0001585.1	0.28	Alkaloid	melinacidin IV	Escovopsis weberi
BGC0001479.1	0.27	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0000953.1	0.27	Saccharide	amicetin	Streptomyces vinaceusdrappus
BGC0001132.1	0.27	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000876.1	0.27	Other	neopolyoxin C	Streptomyces tendae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.68	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.65	NRP	indigoidine	Streptomyces chromofuscus
BGC0000457.1	0.65	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000900.1	0.65	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.64	NRP	dimethylcoprogen	Alternaria alternata
BGC0001585.1	0.62	Alkaloid	melinacidin IV	Escovopsis weberi
BGC0001479.1	0.61	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0000953.1	0.60	Saccharide	amicetin	Streptomyces vinaceusdrappus
BGC0001132.1	0.60	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000876.1	0.60	Other	neopolyoxin C	Streptomyces tendae

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 74839 - 121121:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg4_88

Search NORINE for peptide: strict or relaxed

AMP-binding (10..414): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: hisSrAApqK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 40% (weak)

AMP-binding (1101..1517): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ssrDLaMgiK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 40% (weak)

ctg4_89

Search NORINE for peptide: strict or relaxed

AMP-binding (21..420): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: asahaArhIK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 30% (weak)

c00004_NZ_QGGH.. - Region 2 - lassopeptide

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Location: 163,069 - 185,512 nt. (total: 22,444 nt) Show pHMM detection rules used

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Lasso peptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001549.1	0.35	RiPP	citrulassin B	Streptomyces aurantiacus JA 4570
BGC0001356.1	0.33	RiPP	paeninodin	Paenibacillus dendritiformis C454
BGC0001634.1	0.32	RiPP	keywimysin	Streptomyces sp. NRRL F-5702
BGC0000575.1	0.32	RiPP	lariatin	Rhodococcus jostii
BGC0001655.1	0.32	RiPP	LP2006	Nocardiopsis alba DSM 43377
BGC0001552.1	0.31	RiPP	citrulassin F	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0001550.1	0.31	RiPP	citrulassin D	Streptomyces katrae
BGC0001548.1	0.31	RiPP	citrulassin A	Streptomyces albulus
BGC0001176.1	0.30	RiPP	streptomonomicin	Streptomonospora alba
BGC0001496.1	0.29	RiPP	actinokineosin	Actinokineospora spheciospongiae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001549.1	0.68	RiPP	citrulassin B	Streptomyces aurantiacus JA 4570
BGC0001356.1	0.66	RiPP	paeninodin	Paenibacillus dendritiformis C454
BGC0001634.1	0.66	RiPP	keywimysin	Streptomyces sp. NRRL F-5702
BGC0000575.1	0.66	RiPP	lariatin	Rhodococcus jostii
BGC0001655.1	0.65	RiPP	LP2006	Nocardiopsis alba DSM 43377
BGC0001552.1	0.65	RiPP	citrulassin F	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0001550.1	0.65	RiPP	citrulassin D	Streptomyces katrae
BGC0001548.1	0.64	RiPP	citrulassin A	Streptomyces albulus
BGC0001176.1	0.64	RiPP	streptomonomicin	Streptomonospora alba
BGC0001496.1	0.62	RiPP	actinokineosin	Actinokineospora spheciospongiae

Similar known gene clusters

Lasso peptide predictions

Lassopeptide(s) for ctg4_152 - Putative Class II

ctg4_152 leader / core peptide / cleaved tail: MEQNVEKHEYETPSLTVHGSIETITQ - GGGGSTAIDASFPAHTPIGDLTFS

Legend:

Red: Putative macrolactam
Purple: Putative cleaved off residues

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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Lasso peptides

Core peptide predictions

ctg4_152 - Class II: Cleavage pHMM score: -0.30; RODEO score: 27; Monoisotopic mass: 2257.1 Da; Molecular weight: 2258.4 Da; Number of bridges: 0

c00004_NZ_QGGH.. - Region 3 - RRE-containing

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Location: 190,099 - 210,383 nt. (total: 20,285 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001645.1	0.21	RiPP	lagmysin	Streptomyces sp. NRRL S-118
BGC0001779.1	0.21	RiPP	siamycin	Streptomyces nodosus
BGC0001549.1	0.20	RiPP	citrulassin B	Streptomyces aurantiacus JA 4570
BGC0001634.1	0.20	RiPP	keywimysin	Streptomyces sp. NRRL F-5702
BGC0001176.1	0.19	RiPP	streptomonomicin	Streptomonospora alba
BGC0001889.1	0.18	RiPP	fusilassin	Thermobifida fusca YX
BGC0000761.1	0.17	Saccharide	exopolysaccharide	Methylobacillus sp. 12S
BGC0000780.1	0.17	Saccharide	O&K-antigen	Vibrio parahaemolyticus
BGC0000760.1	0.17	Saccharide	emulsan	Acinetobacter venetianus RAG-1 = CIP 110063
BGC0001947.1	0.17	Saccharide	K53 capsular polysaccharide	Acinetobacter baumannii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001645.1	0.54	RiPP	lagmysin	Streptomyces sp. NRRL S-118
BGC0001779.1	0.54	RiPP	siamycin	Streptomyces nodosus
BGC0001549.1	0.52	RiPP	citrulassin B	Streptomyces aurantiacus JA 4570
BGC0001634.1	0.52	RiPP	keywimysin	Streptomyces sp. NRRL F-5702
BGC0001176.1	0.51	RiPP	streptomonomicin	Streptomonospora alba
BGC0001889.1	0.49	RiPP	fusilassin	Thermobifida fusca YX
BGC0000761.1	0.49	Saccharide	exopolysaccharide	Methylobacillus sp. 12S
BGC0000780.1	0.49	Saccharide	O&K-antigen	Vibrio parahaemolyticus
BGC0000760.1	0.48	Saccharide	emulsan	Acinetobacter venetianus RAG-1 = CIP 110063
BGC0001947.1	0.48	Saccharide	K53 capsular polysaccharide	Acinetobacter baumannii

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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c00004_NZ_QGGH.. - Region 4 - hserlactone

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Location: 486,047 - 506,685 nt. (total: 20,639 nt) Show pHMM detection rules used

hserlactone: Autoind_synth

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000853.1	0.24	Other	ectoine	Streptomyces anulatus
BGC0000860.1	0.24	Other	ectoine	Methylarcula marina
BGC0000858.1	0.24	Other	ectoine	Methylobacter marinus
BGC0000857.1	0.23	Other	ectoine	Methylophaga alcalica
BGC0000855.1	0.23	Other	ectoine	Methylomicrobium kenyense
BGC0000856.1	0.23	Other	ectoine	Methylophaga thalassica
BGC0000854.1	0.23	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000859.1	0.23	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000852.1	0.23	Other	ectoine	Sporosarcina pasteurii
BGC0000919.1	0.16	Other	phaseolotoxin	Pseudomonas syringae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000853.1	0.57	Other	ectoine	Streptomyces anulatus
BGC0000860.1	0.57	Other	ectoine	Methylarcula marina
BGC0000858.1	0.57	Other	ectoine	Methylobacter marinus
BGC0000857.1	0.57	Other	ectoine	Methylophaga alcalica
BGC0000855.1	0.57	Other	ectoine	Methylomicrobium kenyense
BGC0000856.1	0.56	Other	ectoine	Methylophaga thalassica
BGC0000854.1	0.56	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000859.1	0.56	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000852.1	0.56	Other	ectoine	Sporosarcina pasteurii
BGC0000919.1	0.46	Other	phaseolotoxin	Pseudomonas syringae

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00005_NZ_QGGH.. - Region 1 - RRE-containing

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Location: 2,753 - 23,181 nt. (total: 20,429 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001551.1	0.20	RiPP	citrulassin E	Streptomyces glaucescens
BGC0000554.1	0.17	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001120.1	0.16	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0001407.1	0.16	RiPP	bicereucin	Bacillus cereus SJ1
BGC0001526.1	0.16	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0001525.1	0.16	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0000744.1	0.16	Saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000745.1	0.16	Saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000741.1	0.16	Saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000500.1	0.16	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001551.1	0.52	RiPP	citrulassin E	Streptomyces glaucescens
BGC0000554.1	0.48	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001120.1	0.47	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0001407.1	0.47	RiPP	bicereucin	Bacillus cereus SJ1
BGC0001526.1	0.47	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0001525.1	0.47	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0000744.1	0.47	Saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000745.1	0.47	Saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000741.1	0.47	Saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000500.1	0.46	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum

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c00007_NZ_QGGH.. - Region 1 - terpene

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Location: 234,629 - 255,528 nt. (total: 20,900 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000698.1	0.15	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0000703.1	0.15	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000666.1	0.15	Terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0002009.1	0.13	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina
BGC0001633.1	0.12	Other	ketomemicin B3, ketomemicin B4	Streptomyces mobaraensis NBRC 13819 = DSM 40847
BGC0000889.1	0.09	Other	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0002029.1	0.08	Other	bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C	Streptomyces lunaelactis
BGC0001592.1	0.08	Other	ferroverdin	Streptomyces lunaelactis
BGC0001553.1	0.07	NRP, Polyketide	clifednamide A	Streptomyces sp. JV178
BGC0001726.1	0.07	NRP, Polyketide	pactamides	Streptomyces pactum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000698.1	0.46	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0000703.1	0.45	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000666.1	0.45	Terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0002009.1	0.42	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina
BGC0001633.1	0.40	Other	ketomemicin B3, ketomemicin B4	Streptomyces mobaraensis NBRC 13819 = DSM 40847
BGC0000889.1	0.34	Other	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0002029.1	0.32	Other	bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C	Streptomyces lunaelactis
BGC0001592.1	0.32	Other	ferroverdin	Streptomyces lunaelactis
BGC0001553.1	0.28	NRP, Polyketide	clifednamide A	Streptomyces sp. JV178
BGC0001726.1	0.27	NRP, Polyketide	pactamides	Streptomyces pactum

Similar known gene clusters

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Detailed TIGRFAM domain annotation

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c00009_NZ_QGGH.. - Region 1 - T3PKS

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Location: 53,428 - 94,369 nt. (total: 40,942 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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core biosynthetic genes

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NRPS/PKS domains

MIBiG comparison

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Pfam domains

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Detailed domain annotation

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Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001938.1	0.35	Polyketide	entotheonella	Candidatus Entotheonella serta
BGC0001962.1	0.35	Polyketide	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0001905.1	0.32	Polyketide	violapyrone B	Streptomyces somaliensis
BGC0001831.1	0.24	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001538.1	0.19	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001525.1	0.17	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0001444.1	0.17	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0000225.1	0.17	Polyketide	frenolicin B	Streptomyces roseofulvus
BGC0000938.1	0.17	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0001526.1	0.17	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001938.1	0.68	Polyketide	entotheonella	Candidatus Entotheonella serta
BGC0001962.1	0.68	Polyketide	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0001905.1	0.66	Polyketide	violapyrone B	Streptomyces somaliensis
BGC0001831.1	0.57	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001538.1	0.51	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001525.1	0.48	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0001444.1	0.48	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0000225.1	0.48	Polyketide	frenolicin B	Streptomyces roseofulvus
BGC0000938.1	0.48	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0001526.1	0.48	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099

Similar known gene clusters

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Detailed TIGRFAM domain annotation

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c00013_NZ_QGGH.. - Region 1 - hserlactone

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Location: 111,579 - 132,247 nt. (total: 20,669 nt) Show pHMM detection rules used

hserlactone: Autoind_synth

Legend:

core biosynthetic genes

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Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001591.1	0.17	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.17	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001525.1	0.17	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0001343.1	0.17	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001526.1	0.17	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0000554.1	0.16	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000500.1	0.16	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0001407.1	0.16	RiPP	bicereucin	Bacillus cereus SJ1
BGC0001765.1	0.16	Saccharide	salecan	Agrobacterium tumefaciens
BGC0000513.1	0.16	RiPP	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001591.1	0.48	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.48	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001525.1	0.48	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0001343.1	0.48	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001526.1	0.48	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0000554.1	0.47	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000500.1	0.47	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0001407.1	0.47	RiPP	bicereucin	Bacillus cereus SJ1
BGC0001765.1	0.47	Saccharide	salecan	Agrobacterium tumefaciens
BGC0000513.1	0.47	RiPP	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338

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c00015_NZ_QGGH.. - Region 1 - phosphonate

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Location: 45,129 - 86,037 nt. (total: 40,909 nt) Show pHMM detection rules used

phosphonate: phosphonates

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Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000897.1	0.30	Other	dehydrophos	Streptomyces luridus
BGC0001859.1	0.28	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000846.1	0.26	Other	tabtoxin	Pseudomonas syringae
BGC0000802.1	0.24	Saccharide	succinoglycan	Sinorhizobium meliloti
BGC0001336.1	0.24	Alkaloid	erdasporine A, erdasporine B, erdasporine C	uncultured bacterium
BGC0000885.1	0.22	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0001184.1	0.21	Other	bacilysin	Bacillus velezensis FZB42
BGC0000888.1	0.21	Other	bacilysin	Bacillus sp. CS93
BGC0000937.1	0.20	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0001538.1	0.19	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000897.1	0.64	Other	dehydrophos	Streptomyces luridus
BGC0001859.1	0.62	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000846.1	0.59	Other	tabtoxin	Pseudomonas syringae
BGC0000802.1	0.58	Saccharide	succinoglycan	Sinorhizobium meliloti
BGC0001336.1	0.57	Alkaloid	erdasporine A, erdasporine B, erdasporine C	uncultured bacterium
BGC0000885.1	0.55	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0001184.1	0.54	Other	bacilysin	Bacillus velezensis FZB42
BGC0000888.1	0.54	Other	bacilysin	Bacillus sp. CS93
BGC0000937.1	0.53	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0001538.1	0.52	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937

Similar known gene clusters

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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c00016_NZ_QGGH.. - Region 1 - hserlactone

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Location: 67,997 - 88,641 nt. (total: 20,645 nt) Show pHMM detection rules used

hserlactone: Autoind_synth

Legend:

core biosynthetic genes

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Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001488.1	0.15	Other	4-formylaminooxyvinylglycine	Pseudomonas fluorescens WH6
BGC0001765.1	0.13	Saccharide	salecan	Agrobacterium tumefaciens
BGC0001380.1	0.13	Saccharide	salecan	Agrobacterium sp. ZX09
BGC0000926.1	0.09	Other	rhizocticin A	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001671.1	0.09	NRP	monobactam	Agrobacterium tumefaciens
BGC0000608.1	0.09	RiPP	nocathiacin	Actinokineospora fastidiosa
BGC0001417.1	0.07	NRP, Polyketide	myxochromide D	Cystobacterineae bacterium
BGC0000613.1	0.07	RiPP	thiomuracin A	Nonomuraea sp. Bp3714-39
BGC0001005.1	0.07	NRP, Polyketide	locillomycin	Bacillus subtilis
BGC0001860.1	0.07	RiPP	thiomuracin	Thermobispora bispora DSM 43833

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001488.1	0.45	Other	4-formylaminooxyvinylglycine	Pseudomonas fluorescens WH6
BGC0001765.1	0.42	Saccharide	salecan	Agrobacterium tumefaciens
BGC0001380.1	0.42	Saccharide	salecan	Agrobacterium sp. ZX09
BGC0000926.1	0.33	Other	rhizocticin A	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001671.1	0.33	NRP	monobactam	Agrobacterium tumefaciens
BGC0000608.1	0.33	RiPP	nocathiacin	Actinokineospora fastidiosa
BGC0001417.1	0.29	NRP, Polyketide	myxochromide D	Cystobacterineae bacterium
BGC0000613.1	0.29	RiPP	thiomuracin A	Nonomuraea sp. Bp3714-39
BGC0001005.1	0.29	NRP, Polyketide	locillomycin	Bacillus subtilis
BGC0001860.1	0.29	RiPP	thiomuracin	Thermobispora bispora DSM 43833

Similar known gene clusters

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Detailed TIGRFAM domain annotation

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c00031_NZ_QGGH.. - Region 1 - hserlactone

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Location: 1 - 11,187 nt. (total: 11,187 nt) Show pHMM detection rules used

Region on contig edge.

hserlactone: Autoind_synth

Legend:

core biosynthetic genes

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Similar gene clusters

Analysis type:

Reference	hserlactone	Similarity score	Type	Compound(s)	Organism
BGC0001671.1		0.07	NRP	monobactam	Agrobacterium tumefaciens
BGC0000144.1		0.03	Polyketide	salinomycin	Streptomyces albus

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0001671.1		0.29	NRP	monobactam	Agrobacterium tumefaciens
BGC0000144.1		0.15	Polyketide	salinomycin	Streptomyces albus

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Detailed Pfam domain annotation

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