LOCUS       c00031_NZ_QGGH..       11187 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_QGGH01000031.1 Mesorhizobium loti strain DSM 2626 Ga0215673_131,
            whole genome shotgun sequence.
ACCESSION   NZ_QGGH01000031
VERSION     NZ_QGGH01000031
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:21:03
            Original ID  :: NZ_QGGH01000031.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11187
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..126
                     /locus_tag="ctg31_1"
                     /transl_table=11
                     /translation="RVKSIEAFERIQVLPHPIGGPDRVDGKPNGAQNVRALHNQL"
     protocluster    1..11187
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[554:1187](-)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(555..1187)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     cand_cluster    1..11187
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11187
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="hserlactone"
                     /region_number="1"
                     /rules="Autoind_synth"
                     /tool="antismash"
     CDS             complement(302..553)
                     /locus_tag="ctg31_2"
                     /transl_table=11
                     /translation="MVMIGNDADWPDWQDEKSYRHTRHLTQRGWGWEFLRRNPAFQRDL
                     RHALEHAEFAERRFDIEVVRSSLDLTRWGLLFCKLVEA"
     PFAM_domain     complement(317..523)
                     /aSDomain="DUF6499"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF20109.1"
                     /description="Family of unknown function (DUF6499)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg31_2_0001"
                     /evalue="2.10E-07"
                     /label="ctg31_2"
                     /locus_tag="ctg31_2"
                     /protein_end="79"
                     /protein_start="10"
                     /score="31.1"
                     /tool="antismash"
                     /translation="PDWQDEKSYRHTRHLTQRGWGWEFLRRNPAFQRDLRHALEHAEFA
                     ERRFDIEVVRSSLDLTRWGLLFCK"
     CDS             complement(555..1187)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_3"
                     /sec_met_domain="Autoind_synth (E-value: 4.4e-43, bitscore:
                     137.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIELIAPGWYGAFADELHEMHRVRYRVFKERLDWNVRTTGGFEID
                     SFDSLKPHYLVSRGSARRVGGGVRPLASTGPTMLRDVFSRLLEGRAAPEEPSVRESSRF
                     ALDLPPSAPKGSGSIAVATYELLAGMIEFGLSRQLTHIVTVTDLRMELFLRRAGWPLAR
                     IGPPQTIGTTRAFAGFLDVSEESLAAVRHNGGLGGPVLWAPVICTGA"
     PFAM_domain     complement(621..1142)
                     /aSDomain="Autoind_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00765.19"
                     /description="Autoinducer synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg31_3_0002"
                     /evalue="1.60E-45"
                     /label="ctg31_3"
                     /locus_tag="ctg31_3"
                     /protein_end="189"
                     /protein_start="15"
                     /score="155.0"
                     /tool="antismash"
                     /translation="ELHEMHRVRYRVFKERLDWNVRTTGGFEIDSFDSLKPHYLVSRGS
                     ARRVGGGVRPLASTGPTMLRDVFSRLLEGRAAPEEPSVRESSRFALDLPPSAPKGSGSI
                     AVATYELLAGMIEFGLSRQLTHIVTVTDLRMELFLRRAGWPLARIGPPQTIGTTRAFAG
                     FLDVSEESLAA"
     CDS             complement(1288..2013)
                     /gene_functions="regulatory (smcogs)
                     SMCOG1197:autoinducer-binding transcriptional regulator,
                     (Score: 165.2; E-value: 2.6e-50)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg31_4"
                     /transl_table=11
                     /translation="MQLVFETLLEQLSLSVDEVDFHNALANAAGAFDIPAFAYLSLVSD
                     GVTKPRLISNYHSGWTSHYLRHQYERIDPVIERARCSECPFQWGRGFGHAGISKREQQL
                     FDEAAEFGICCGLTIPLVDRRGGVAAMTFAADRLDPSFMRIAEQYEQALEIMATCFHIG
                     VRRKLSGGLAVDGVSLTPREYECLEWTAKGKSAWEIGCILGIKERTAAFHLDNAKKKLG
                     VRTKNQAVTLLASSRSSIL"
     PFAM_domain     complement(1318..1482)
                     /aSDomain="GerE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00196.21"
                     /description="Bacterial regulatory proteins, luxR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg31_4_0004"
                     /evalue="4.70E-17"
                     /label="ctg31_4"
                     /locus_tag="ctg31_4"
                     /protein_end="232"
                     /protein_start="177"
                     /score="61.4"
                     /tool="antismash"
                     /translation="SLTPREYECLEWTAKGKSAWEIGCILGIKERTAAFHLDNAKKKLG
                     VRTKNQAVTL"
     PFAM_domain     complement(1531..1956)
                     /aSDomain="Autoind_bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03472.17"
                     /description="Autoinducer binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg31_4_0003"
                     /evalue="4.00E-28"
                     /label="ctg31_4"
                     /locus_tag="ctg31_4"
                     /protein_end="161"
                     /protein_start="19"
                     /score="97.8"
                     /tool="antismash"
                     /translation="DFHNALANAAGAFDIPAFAYLSLVSDGVTKPRLISNYHSGWTSHY
                     LRHQYERIDPVIERARCSECPFQWGRGFGHAGISKREQQLFDEAAEFGICCGLTIPLVD
                     RRGGVAAMTFAADRLDPSFMRIAEQYEQALEIMATCFH"
     CDS             2669..2854
                     /locus_tag="ctg31_5"
                     /transl_table=11
                     /translation="MMGSGERGLKATRGQLTGSIDAEHRPFRGGETEHLRRRRPHSVPA
                     LIVVLAIYRDFGLPLA"
     CDS             complement(2816..3307)
                     /locus_tag="ctg31_6"
                     /transl_table=11
                     /translation="MPHVVWLPRSVVDVMKSDADQWYDKETGGTFMGYWAETRVAVVTR
                     MIPAGPNAKRTRCSFLPDQDWQQAEIAKDYHRSGRLDTYLGDWHTHPDTFSNRLSRTDR
                     ACLRNVIGTPSARASTPIMMLMCGKTARWMLHAWVCGMGPRFFLLEGLCEWKAEVAVYG
                     "
     PFAM_domain     complement(2909..3283)
                     /aSDomain="Prok-JAB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14464.8"
                     /description="Prokaryotic homologs of the JAB domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg31_6_0005"
                     /evalue="1.10E-09"
                     /label="ctg31_6"
                     /locus_tag="ctg31_6"
                     /protein_end="133"
                     /protein_start="8"
                     /score="38.2"
                     /tool="antismash"
                     /translation="RSVVDVMKSDADQWYDKETGGTFMGYWAETRVAVVTRMIPAGPNA
                     KRTRCSFLPDQDWQQAEIAKDYHRSGRLDTYLGDWHTHPDTFSNRLSRTDRACLRNVIG
                     TPSARASTPIMMLMCGKTARW"
     CDS             complement(3295..5049)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_7"
                     /sec_met_domain="ThiF (E-value: 6.7e-33, bitscore: 104.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPYVDLKSAEVPKWEEDPVNRNRMRAELDHLFHFGGSTLLVDEI
                     ALADGVLHVEFRWPLPDGRLIDLEAIYPDSFPRLRPHVVLRCEPEQYPSRHCAPDGSLC
                     LLGRDSGLWQSRMTLADILYSNLAKALDASEDEDPQGEPAEVWWNEAADRGSGNYVLVD
                     SSWDLSGFDQGKVEIEFVVDWGKDRPAIQAAVSKVWSDTGELLAERSFPLPITLERRRD
                     TAVFPWKRDDHLPMPVPQELPSLLKRLGHGSRYAKTSGGDIRISATIKRSELQFQTYGE
                     AWVFVLHYSKNILRITRNGAQKTREVGFVVSTYRAGIGDIGSRVPSVGALRDKTIAIVG
                     LGALGSPLAVELAKNGCRKLIVLDCDYVEPGNSIRWAAGASAWGRQKIEFIKEHIELEY
                     PWTTVQPISHRIGSAGSGADGVGDHQLLTGLMDEANLVIDAAASTGVSFFLGDCCRALH
                     VPMICVYASTTLKGGIVAFHHPESGCPVCKEISYATGTIDRPPGMGDSQGLIQPPGCSE
                     ATFKGASFDLQELTLEAVRMAVDVLSRPQDFEVSLVHTLALHDGLKRIPPAWKVDELQP
                     SPECGCLT"
     PFAM_domain     complement(3616..4062)
                     /aSDomain="ThiF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00899.23"
                     /description="ThiF family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg31_7_0006"
                     /evalue="1.80E-12"
                     /label="ctg31_7"
                     /locus_tag="ctg31_7"
                     /protein_end="478"
                     /protein_start="329"
                     /score="47.0"
                     /tool="antismash"
                     /translation="ALRDKTIAIVGLGALGSPLAVELAKNGCRKLIVLDCDYVEPGNSI
                     RWAAGASAWGRQKIEFIKEHIELEYPWTTVQPISHRIGSAGSGADGVGDHQLLTGLMDE
                     ANLVIDAAASTGVSFFLGDCCRALHVPMICVYASTTLKGGIVAFH"
     CDS             5903..6160
                     /locus_tag="ctg31_8"
                     /transl_table=11
                     /translation="MSPKTVGIIGGLGPMATVAFMNSVLEYTPIKSNARSFIVEPQHGS
                     SGLARASQMLFEPGTGQLQQLWCRLQVDLGAKEVLMAQIG"
     CDS             complement(6729..7217)
                     /gene_functions="regulatory (smcogs) SMCOG1120:AsnC family
                     transcriptional regulator (Score: 134.6; E-value: 3.5e-41)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg31_9"
                     /transl_table=11
                     /translation="MLNLQVWLGHQTVDDLDKRILTALQRNNRHSFADLAELVGSSAAS
                     CMRRVNKLRAEGVIVADISLVDPKALGKSLTIVVTVELDRERLDLVDDFKRAMRAAKEV
                     TQCYMVTGDADFVLVVAVEDVEAFDVFVKTKLYTNPNVRKFRSMISLDRVKFEPRVTV"
     PFAM_domain     complement(6762..6983)
                     /aSDomain="AsnC_trans_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01037.23"
                     /description="Lrp/AsnC ligand binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg31_9_0008"
                     /evalue="1.60E-20"
                     /label="ctg31_9"
                     /locus_tag="ctg31_9"
                     /protein_end="152"
                     /protein_start="78"
                     /score="72.9"
                     /tool="antismash"
                     /translation="VTVELDRERLDLVDDFKRAMRAAKEVTQCYMVTGDADFVLVVAVE
                     DVEAFDVFVKTKLYTNPNVRKFRSMISLD"
     PFAM_domain     complement(7041..7178)
                     /aSDomain="HTH_24"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13412.8"
                     /description="Winged helix-turn-helix DNA-binding"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg31_9_0007"
                     /evalue="1.30E-13"
                     /label="ctg31_9"
                     /locus_tag="ctg31_9"
                     /protein_end="59"
                     /protein_start="13"
                     /score="50.3"
                     /tool="antismash"
                     /translation="DDLDKRILTALQRNNRHSFADLAELVGSSAASCMRRVNKLRAEGV
                     I"
     CDS             complement(8672..8896)
                     /locus_tag="ctg31_10"
                     /transl_table=11
                     /translation="MTTSVWPQLREIDHVADAARGIDLFDHHQRQPSIGHRQTQAKEEA
                     WKGARQGKPLRRTVDGIRWFRYSISSTEA"
     CDS             complement(8973..9698)
                     /locus_tag="ctg31_11"
                     /transl_table=11
                     /translation="MHNSHLADEIIAWRRHLHLNPELDFDMHETTRFVRSWRPLESTTS
                     KWGHWHSSVHREGPTIHACGHGGHGGHTAMLGYGNSGHRCAHVPGGRGSRTTVGRAQNG
                     RGRLFGPFWHLPGLAVSRPLKPTSSRATRPRSAASDRSRLRTTFSSIRFHGNSRHPGTP
                     PISYRAYRVGRTLRLCHRDRRARATMYSCPDPLRPRRATNSPFSMSRPRPSRTVRGPTP
                     QGSRPAPGARRSIRQGAAP"
     CDS             9942..10499
                     /gene_functions="regulatory (smcogs) SMCOG1120:AsnC family
                     transcriptional regulator (Score: 70.1; E-value: 2.6e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg31_12"
                     /transl_table=11
                     /translation="MISTGGYSAPFKRTTGCHSPNSRISWVRLPLHACAVSISYVPSAA
                     CVITADISLVDPKALGKSLTVVVTVELDRERLDLVDDFKRAMRAAKEVTQCYMITGDAD
                     FVLIVAVEDVEAFDVFVKTKLYTNPNARKFKSMIALDRVKFEPRVLALLWQIFSGEGSA
                     ALGTTDWGRLRERGDDGLPNGG"
     PFAM_domain     10143..10364
                     /aSDomain="AsnC_trans_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01037.23"
                     /description="Lrp/AsnC ligand binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg31_12_0009"
                     /evalue="1.00E-19"
                     /label="ctg31_12"
                     /locus_tag="ctg31_12"
                     /protein_end="141"
                     /protein_start="67"
                     /score="70.4"
                     /tool="antismash"
                     /translation="VTVELDRERLDLVDDFKRAMRAAKEVTQCYMITGDADFVLIVAVE
                     DVEAFDVFVKTKLYTNPNARKFKSMIALD"
ORIGIN
        1 cgcgtgaaga gcattgaggc attcgagcgc attcaggtgc tgcctcatcc gatcggcggg
       61 ccagatcgcg tcgacggaaa gccgaacggg gcgcaaaacg tccgcgccct ccacaaccag
      121 ttgtaaatcc cggtgagcat ttcgcagcat gacatgctgg cgaccgtccg ccgtgatcac
      181 gagtgccgcc cgacatggca atgcagcgag atcaaacgaa aacgtttcgg gcgacaatgc
      241 cctttctgca atgagcggca ggacatgcgg gcattggcgg gagcaccaga acacattcgc
      301 atcaggcctc aacgagcttg caaaacagga gcccccaccg cgtcagatcg agcgacgatc
      361 tcaccacttc tatgtcgaag cgcctttctg caaattctgc gtgctcaagc gcgtgcctca
      421 agtcacgctg gaaggccgga ttgcgccgca ggaattccca gccccagccg cgttgcgtca
      481 ggtgccgcgt atgacgatag gatttctcat cctgccagtc cggccagtcg gcatcattac
      541 caatcataac catatcaggc gcccgtgcag atcaccggcg cccacagcac aggaccgcca
      601 agaccgccat tgtggcggac tgcagcaagg ctctcctctg agacatccaa aaagccggca
      661 aaggcgcgcg tggtgccgat tgtctggggc ggaccgatcc gggcgagcgg ccatccggcg
      721 cgacgcagga atagctccat gcgcaaatcc gtaaccgtga cgatatgggt gagttgccgt
      781 gacaaaccga actcgatcat gccggcgaga agttcatagg tggcaacagc tatactccca
      841 ctgcccttcg gtgcagacgg tggaagatca agggcgaaac ggctgctttc ccggacactc
      901 ggttcctcgg gtgccgctct cccttccaac agcctcgaaa agacgtctcg cagcatcgtc
      961 ggtcccgtcg aggccagagg gcgtacgccg cccccgacgc gacgggcgga accgcgcgac
     1021 acgagatagt gcggtttcag ggaatcgaat gaatcgatct cgaagccgcc ggtcgtgcgc
     1081 acgttccagt ccagccgttc cttgaagacg cggtagcgca cgcggtgcat ttcgtgaagt
     1141 tcgtcggcaa aggcgccgta ccagccgggc gcaataagct cgatcatgat ggtctcctcg
     1201 caggtatgac cctgccattg gaggcgaacc ttcatgccgc gactgcctgt gcatttgcac
     1261 aggtagatca aagagggatt ctgtccctca gagaattgat gatcgggagg aggccagcag
     1321 tgtcactgcc tgatttttgg tgcgcacgcc gagcttcttc ttggcattgt ccagatggaa
     1381 agcggccgtg cgctccttga tccccaagat acagccgatc tcccaggcgg acttgccctt
     1441 cgccgtccat tccaggcatt cgtactcacg gggcgtcagc gaaacaccat ccaccgccag
     1501 accacccgaa agcttgcggc gaacgccaat gtgaaagcac gtcgccataa tctcgagcgc
     1561 ttgctcatat tgctcggcga tgcgcataaa gctcggatcg agcctgtctg ccgcgaaggt
     1621 catcgcagcg acaccgccgc ggcggtcgac aagtggaatc gtcagtccgc agcagatgcc
     1681 gaattcggca gcctcatcga aaagctgttg ctctcgcttt gaaatgccgg catggccgaa
     1741 accccgtccc cactgaaagg gacattcgct gcatcttgcc cgttctatga ccgggtcaat
     1801 cctttcatat tggtggcgca agtagtgcga cgtccagccg gaatgatagt tcgatatcag
     1861 cctgggtttt gtgacgccat cagacacaag agacagatag gcgaatgcgg gaatgtcgaa
     1921 ggcgccggcg gcgttggcca gtgcgttatg gaaatcgact tcatcgacgc tcaaagacaa
     1981 ctgttccagc agagtttcga agacgagttg cattttctcc tgcgctgttt tcatttaaac
     2041 tttggagttc tgacttcttg cggcgaggag actcgccccc gagatatttg gcgccggaga
     2101 aaattcacct ccccggaggt tcgatcatgt gaagcgagac gcgtgcgaca acgccggctg
     2161 cggtcagccg cgcgtcggaa gctgcgattg aggcggttgc catggcatgt cagaaatatc
     2221 gaagctcgat gtgccatcga tatattcaga tgacctcctt ctcgaactct tgattgagcg
     2281 cgctacaatg acccctccca gcgggtcaaa caaggcgccc tgccggcggg gaggtacacc
     2341 ggcagggcgc gcggcgccgg gcattaacga gttcgggcga gtcttcttca ttttagccgc
     2401 ctccatcgga gcgccttgcg cggcatgttg cagtttacaa gggccgtctg tgcgatcaac
     2461 gtgccgaact gtgatttaac cgacgcttat cctaagatta ctctttcctt ccgagcaata
     2521 tgatactgat ctgcagagac gccaatatgc tgactaacag gcttctctga ttaggggtcg
     2581 gtcaggtcaa gcttttcctg ccttcttccc ggatcatgtc ggcccgcggg tcactcgctt
     2641 ctttccgcgg tcggcgcgga gccgccgcat gatggggtca ggagagcgag gcctgaaggc
     2701 tacccgcggc cagctgaccg gatcgatcga tgcggaacat cgtccattta gaggtggcga
     2761 gacggagcat ttgcgtcgcc gtcgccccca ctctgttccc gcgctaattg tcgttttagc
     2821 catataccgc gacttcggcc ttccactcgc ataggccttc taacaagaag aaacgtggcc
     2881 ccattccgca aacccaggcg tgcagcatcc atctggctgt tttgccgcac atcagcatca
     2941 taatcggggt agaagcccgc gcagacggcg ttccgatgac gttcctgaga caggctcgat
     3001 ctgttcggct caatctgttg gaaaatgtgt ccgggtgcgt atgccaatcg ccgaggtagg
     3061 tgtcgagcct acctgatcga tgatagtcct tagcgatctc ggcctgttgc cagtcttgat
     3121 cgggaagaaa gctgcagcgt gtgcgcttcg cgttggggcc ggccgggatc attctcgtga
     3181 ccacggctac acgggtttcg gcccagtagc ccatgaaggt tccacccgtt tccttgtcat
     3241 accattggtc ggcatcagac ttcatcacgt caaccacgga gcgaggaagc cagactacgt
     3301 gaggcatccg cactccggac tgggctgcaa ttcatccacc ttccaagctg gcggtattcg
     3361 cttcaaacca tcgtgcagag ccagggtatg gacgagcgac acctcgaagt cctgcgggcg
     3421 ggaaagcacg tcgactgcca tccgaacggc ttcgagcgtc agctcctgga gatcgaacga
     3481 agcgcctttg aaggttgcct cggagcagcc cggcggctga atcaggccct gagagtcgcc
     3541 catgccggga ggtctatcaa tcgtgccggt cgcataggag atctctttgc agaccgggca
     3601 gccggattcc gggtgatgga aggcaacaat ccctcccttc agtgtcgtcg aggcatagac
     3661 gcagatcatt ggaacatgga gcgctcggca gcaatcgccc aggaaaaagg aaactccggt
     3721 ggaggcagca gcatcgatca ccagattggc ttcgtccatt aagccggtaa ggagctggtg
     3781 gtcccctact ccatccgccc ctgacccagc gctgccgatc ctgtgagata tcggttgcac
     3841 ggtggtccag gggtattcaa gttcgatatg ttccttgatg aactctattt tttgcctgcc
     3901 ccaagctgaa gcacctgcag cccagcggat ggagttcccc ggctcgacat aatcacaatc
     3961 caacacgatc aattttcgac agccgttctt ggccaactcg acagccagcg gcgagcccag
     4021 cgctccgagt cccacgatgg ctatcgtctt gtcgcgcagg gctccgacag aggggactcg
     4081 gctgccaatg tccccgatcc cggccctgta ggtagagaca acgaacccaa cctctctggt
     4141 cttctgcgca ccgttcctgg tgatgcgaag aatgttcttg ctgtagtgca aaacgaaaac
     4201 ccatgcctca ccgtatgtct ggaactgcaa ttcggatctc ttaatcgtgg cggagatccg
     4261 aatgtcgcca ccagaggttt tcgcatagcg cgagccgtga ccgagacgtt ttaacaggct
     4321 cggcagctcc tggggcaccg gcatgggaag atgatcgtcc cgcttccatg gaaacaccgc
     4381 cgtatcccgt cttcgctcaa gggtgattgg gagcggaaag ctgcgctcgg cgagcagctc
     4441 tccggtatcg ctccacacct tcgagacggc ggcctgaatc gccggacgat ctttccccca
     4501 gtccactacg aattcgatct caactttccc ctggtcgaac cccgaaagat cccaggaact
     4561 gtcgaccagc acatagttgc cgctgccgcg atcggcggct tcattccacc aaacctctgc
     4621 cggctcaccc tgggggtcct catcctccga agcatcgagc gctttggcca gattggaata
     4681 aaggatgtcg gccaaagtca tcctactctg ccacaagccg ctgtcccggc cgagcagaca
     4741 tagactgccg tctggggcgc agtgacgcga tgggtattgc tccggttcgc accggagcac
     4801 cacatgaggg cggagccgcg ggaacgagtc gggatatatt gcctcgaggt cgatcaggcg
     4861 cccgtccggc aaaggccatc gaaactcaac gtggaggaca ccgtccgcca acgctatttc
     4921 atcgacgaga agtgtgctcc cgccgaaatg gaaaagatga tccaattcgg cccgcatacg
     4981 attgcggttg actggatctt cttcccattt cggtacttcc gcggatttca gatcgacata
     5041 gggaatcatg cagcgccaac cggcctcggc ggaacgtgcg gagggtcttt cggcccagga
     5101 atgtgtcccg gccgccccgg cgcgtgatcc ggaggatttg gcagatggtc tggaggaccg
     5161 gacggatgat cgggccggcc aggattttca ggctttccag ccatgggagt cttcctttcg
     5221 ctgtttggtt ttcactcatg cgaacgaacg tcgcgtcctc atccggccga ccgaggttcg
     5281 aagaagccgt cgtcgcgcga acatcagaag gatagtagat tcgtgaggga gatttgctcc
     5341 agattacgtc ggctgctgca acgtgggttg cagaaggccc tgcggtttga aatcgtcgac
     5401 ctcggtgcta cactatcaag ggcggccgca aaaaaagcga gaagagcgct cctcgccaaa
     5461 gcctgtccga cagggtcaag actgtgtgca tcgctcggaa aggttagcta atcgaggagt
     5521 gccacgcctg gcgcccgcgc cgcaagcaga ggccattctg gaacggctac agaagctctc
     5581 gaagccgttc ggcaccaatg tcgagatcga aaacgaggtt ggagtgatcc gagtacgggc
     5641 caactcggcg cgtccggtat gtaccgatac agcacccccc catctaatgc gaggtgtgga
     5701 cgacgggatg ggagctgccg tagaataagg atagagtgcc accatggccg cgcatcccaa
     5761 ttggccgact tcgccttgga tgctgatccc ctttttttga tgcctaacgg cgtttcggcg
     5821 gtagaatcca aggtagtcgg tcggcaccag cggcgggctc cctgcgtccg ccggtagtat
     5881 ccataggact tcgaggtttg ttatgtcgcc aaaaacggtc ggaatcatcg gcggcctcgg
     5941 tcccatggcc acggtcgcct tcatgaattc ggttctggag tatacgccga taaagagcaa
     6001 cgctcgcagc ttcattgtcg agccgcaaca tggctcatcg gggttggcgc gcgcatcgca
     6061 gatgctgttc gaaccgggta ctggccaact ccagcagttg tggtgtcgcc ttcaggtaga
     6121 cctcggtgcc aaggaggttc tgatggccca gataggctga cagcatgggc aacttggcgt
     6181 gtacgcgcct tgagcgcgcc aggttgaatt ggacccgatc cgcgaaatcc catacgggcc
     6241 cgcggcatgt gacagccgca acagaagccg gacacatgtc agcacccgac cacgctccgc
     6301 gcccttcgaa aaattgcgaa gattggggcg ctgaacgacg agcttgtcca actggcgcgc
     6361 aacgatgccg ccacacgcag gttgacctcg atccccggca ttggggtgct caacgcgacg
     6421 gctttggtcg cggcagtagg taatgcaagc aactttgcca aggcccgaga ccttggctcc
     6481 tggctcgggt tggttccgag acaatacagc acgggcggca agtctcggct gcttgggaat
     6541 ccaagcgcgg caacacctat ctgcgcactt tgctcccgcg cggcattgcc atcgctttca
     6601 aagagcgaca cgcctttggg ttctgcgaga gccccgttgc gaactctgga ctggagaccg
     6661 cagaagttgg agggaaggcg cttcaaaggc ggctcggatc gattcgcttc agcgcaatct
     6721 gctaaaagct ataccgtgac ccggggctcg aacttaacgc gatcaaggct gatcatactc
     6781 ctaaattttc gcacgttggg gttggtatag agctttgtct tgacaaagac gtcaaaggcc
     6841 tcgacgtcct cgaccgctac gaccaggacg aaatcggcat cgcccgtcac catgtagcac
     6901 tgagttacct ccttggctgc gcgcatcgcg cgcttgaagt cgtcgacaag gtccagacgt
     6961 tcacggtcaa gttcaaccgt cacaacaatg gtaagcgatt tgccaagagc cttcggatcc
     7021 acgagtgaga tatccgcaac gattacgcct tccgcacgca acttgttcac tcgacgcatg
     7081 catgaggcag cggaagaacc gacgagttcc gcgaggtcgg caaaggagtg ccgattgttc
     7141 ctctgtagcg ccgtcaggat ccttttgtct aggtcgtcca ccgtctgatg ccccagccat
     7201 acttggagat ttaacattta cttcgcaatc ttaacaattt cacagttctc cgcaacgttt
     7261 atttcaaatc acgcacaaaa atgaaacaaa aacattcacg gtccggcagt taatcaaata
     7321 tgcgttcacc cgcgctttgt gtgatccgca tgtcagcagt ggcgttttgg caacacgccg
     7381 cactctgccg tttccagcat gcgccagcac attcctcatg aagtgaggcg tgcccgttga
     7441 agaagtccac ttgggcgaac cgctttgaga tgagacggga tccgccttcg catgatggtt
     7501 tggcgtgacc ctcagaccgc tcgtcttgct accgacggct cgatccggag cagcggaata
     7561 ccagccgaag gaactggtcc aaatatgcgg ctgccagccg cttgaggttc acggccggag
     7621 ccgtgagagt aggcctggat tttcatatcg ggaaggccgc gcctggagcc ctgactacct
     7681 cgcctcaatc ctcgaagagc ttcgccgtta acctggattc gtagccctgt ctccgtagcg
     7741 tgttgccgtt cgcatggatc cgtcgatttg aacatgcgaa gaagcctctc ttggaggggc
     7801 tcacgggacg ggttgctggc tggcttgagg tagtcgcagg tccgacgggc ggcggcagcg
     7861 ttcgacgaag gcgcggctcg cgtggagagt cttctgccct gggcgcgggc cgcaaagctg
     7921 gtggccgagg ccatgcctta aggcaacttg agccgtacct tccgatcaga ccgctcgggc
     7981 cagtcataga cctggccgcc gcatggaacg tctcagcgag ttttggtagg cgacgttcaa
     8041 gggacaccgg tttgagcatt cagtgatcct gctttgcatg ctggtatctg gcagtccggc
     8101 gggatcattg ggccccacgt acatcgcgga tcacccgcga cagatgcccg gcatcgacgt
     8161 catgccccgc ccagatcacg gcgtcgccca cgacgctctc gatggaagcc cccgccgcct
     8221 tgttccgcgc cggctcttca tcgcaagcga gcgcggggcc ccgtgcctgc ttgccacctc
     8281 ggccacaggc cggtttcgtc gtggctgacg aacctttcgc caaaaacgac ggcgaactgg
     8341 gtcctggcct cgaaccattc gcgcggtggt cgtttccatt cttcggccgc gtggatcagg
     8401 accagatatc gcagccttat tccttcagaa actccaaatt caagcgcatc cttaccggcc
     8461 agacgttcca acgcgacgac tactatgact actatcatgg cgcggaattt gcattgagag
     8521 ctccgcggct tcactctcgg ctgtccagtc gggcatggcg ggggcgcttc cctgatcacg
     8581 aagcagcacc ctacaaatcc gcgaccagcg caaatccccc ggcagccgca actttctgac
     8641 tctgtaagac taggaggccg tagtccgcgc atcacgcctc ggtcgaagag atgctgtatc
     8701 ggaaccaccg aatcccatca accgttctgc gcaacggctt gccctgccgg gcgcccttcc
     8761 aggcttcttc cttggcctgc gtttggcggt gacctatgct tggctgtctc tggtggtggt
     8821 cgaacaggtc aatgccacga gcggcatcgg ctacatgatc gatctcgcgc aactgcggcc
     8881 agactgacgt cgtcatcgtc ggtcttctcg tctacgcgtt gctcggtctc gtctgcgacg
     8941 gcatcgtccg cttcttccag gaaaggtccc tgtcatggcg ccgcaccttg gcggattgag
     9001 cggcgcgccc ctggtgcggg tcgagagcct tggggggtcg ggccgcgaac cgtcctcgac
     9061 ggcctcggcc tcgacatcga gaagggggag ttcgtcgccc ttctcggccg tagcgggtcg
     9121 gggcatgagt acattgttgc gcgcgctcgc cgatctcgat gacaaagtct cagggtccgg
     9181 ccgactcgat acgcccgata agaaatcggt ggtgttccag gatgccgact gttgccatgg
     9241 aaacgaatgc tggaaaatgt ggttcttagt ctcgacctgt cggacgccgc cgaacgcgga
     9301 cgggtagctc tcgaagaggt tggcttgagc ggccgtgaga ccgcaagacc tgggagatgc
     9361 caaaacggtc caaaaagccg tcctcgacca ttttgagccc gcccgacggt agttcgactt
     9421 cctcggccgc ctggaacatg agcgcaacgg tgccctgaat ttccgtatcc aagcatagcc
     9481 gtatggccgc catggccgcc atggccgcag gcgtgtatgg tcggcccttc gcgatgaacg
     9541 ctactatgcc agtgccccca tttcgatgtg gttgattcca aaggacgcca gcttctcacg
     9601 aaccgtgtcg tctcatgcat atcaaagtcg agttcgggat ttagatgaag atgccggcgc
     9661 caggctatga tctcgtcggc caggtgcgag ttgtgcatgc tgactccgtt catcgacgtc
     9721 tggaggatgt cgtaggctat gtggcggact taatttgccg agagcgtttg gcagagttcg
     9781 ggcaaactcg catttgggtg aaaatgaaac agtctcgttt tcgtggcgat tgcaataata
     9841 gtgcttgtcg gatgggcagc gtttcattga gcggctgttc ttgcaatgaa cgttccagat
     9901 tgctaatgcg acgatgattt cgcatagtgc aggcatgata gatgatctcg accggcggat
     9961 actcggcgcc cttcaaaaga acaacaggct gtcattctcc gaactcgcgg atctcgtggg
    10021 ttcgtctgcc gcttcatgca tgcgccgtgt caataagtta cgtgccgagt gccgcgtgcg
    10081 ttatcaccgc tgatatctcg ctagtcgacc ccaaggcgct cggaaagtcg ctgaccgtgg
    10141 tcgtcacagt ggagctcgac cgcgagcgct tagacctcgt cgacgacttc aagcgagcga
    10201 tgagggcggc gaaagaagtc actcaatgct acatgatcac aggcgatgcc gacttcgttc
    10261 ttattgtagc cgtggaggac gtcgaggcct ttgacgtttt tgtaaagacc aaactctata
    10321 caaatcccaa tgcccgtaag ttcaagagca tgattgcgct ggaccgagtg aagttcgagc
    10381 cacgggtgct agcactactt tggcagattt ttagcggaga gggttctgcg gcactgggga
    10441 caacggattg ggggcggctg cgcgagcgcg gtgacgatgg cttgcctaac ggcgggtagg
    10501 ctcggttgga gcggcgggcc gaggattctt ttttccccct cccgcttgtt tgaggcggcg
    10561 agattgcagg aaggcgtagg cgatcatcgt catcagcgcg tgccggtgca ggcccgtcca
    10621 tgagcgcccc tcgaagtggt cgaggccaag ttcctccttg agctgctgat gcgcctgctc
    10681 gcagacccag cgcgccttga tagcgcctgc gatctgcttg agcggggtgt cggcgggcaa
    10741 gttggagagg tagtatttgc gctcgccggt cgcgcggtgc tcgccgatca cccagacctc
    10801 ctcgccgggc agatgctgag cgcccatgtc gcggatgcgc tggggtgggc catctgcaac
    10861 ccggacacgg acagcggcga agcgcgccga gaggcggcct ttggtgccac gccgccaact
    10921 gaccgtccgc cattgggctt tttccagcat cgcctgcgcg gtcatcgact tcacatcggg
    10981 gatatgccgg cggcgcgggc ggccgcgtcc ggcaacgggg aagatcatcg ccacgtcggc
    11041 ggcatggacc ttctgcttga acgggatgcc gacggcccag atcaggccgc gctctgtgag
    11101 cgcctgccgg aagggggcgc ttaagccata tccggcatcg gcgagcacgc agccaaagca
    11161 taagccggct gcgcgagccc ggtcgat
//
