LOCUS       NZ_KB899874.1           8769 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KB899874.1 Cohnella laeviribosi DSM 21336
            F560DRAFT_scaffold00067.67, whole genome shotgun sequence.
ACCESSION   NZ_KB899874
VERSION     NZ_KB899874.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:30:12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8769
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..156)
                     /locus_tag="ctg67_1"
                     /transl_table=11
                     /translation="MKYKHARKQNQRIQQITESTLVVGADIAKKTHVARAVDFRGIELG
                     KDCVFGN"
     protocluster    1..8769
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5346:5993]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5347..5993
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..8769
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8769
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(275..1147)
                     /gene_functions="transport (smcogs) SMCOG1067:putative ABC
                     transporter permease protein (Score: 249.6; E-value:
                     6.4e-76)"
                     /gene_kind="transport"
                     /locus_tag="ctg67_2"
                     /transl_table=11
                     /translation="LNASRVRRFIAAALLPSVILYALFVFVPVIWSAYYSFFNWSGIGE
                     AKYIGFQNYAELIRDSVFWHSLKNNVIFVLASILGQVPIALVLAILLHKSNALQRFMRA
                     SIFMPMVLSSVVIGMIWQYIYHPQIGILNFLLDALGLGSWKMQWLSDPDISIYALLPPL
                     IWNFVGLYLIIFISALQNIPSEIHDAAKIDGVSGARKLFTITLPMIWGTIQVAIILCIS
                     GSLKSFDLVYVMTKGGPAHATELLATYMYNSTFSTYRYGYGSAISTAIVLISLLFIGTS
                     QWLTRRKAD"
     PFAM_domain     complement(290..907)
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg67_2_0001"
                     /evalue="1.30E-18"
                     /label="ctg67_2"
                     /locus_tag="ctg67_2"
                     /protein_end="286"
                     /protein_start="80"
                     /score="67.5"
                     /tool="antismash"
                     /translation="QVPIALVLAILLHKSNALQRFMRASIFMPMVLSSVVIGMIWQYIY
                     HPQIGILNFLLDALGLGSWKMQWLSDPDISIYALLPPLIWNFVGLYLIIFISALQNIPS
                     EIHDAAKIDGVSGARKLFTITLPMIWGTIQVAIILCISGSLKSFDLVYVMTKGGPAHAT
                     ELLATYMYNSTFSTYRYGYGSAISTAIVLISLLFIGTSQWLTR"
     CDS             complement(1213..2532)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143:sugar-binding lipoprotein (Score: 246.5; E-value:
                     1e-74)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg67_3"
                     /transl_table=11
                     /translation="MKKRFILALAIAVCVSLLAGCGGGQSADNDASGGKQEKITLTLWN
                     NWSGQDAKAVAMRKILDDFKAQHPEIDLQVEALATDGLKTRLRTAAAANEMPDLFVMWP
                     GAMTKEFVNGDLLQPIDDFLNSKPEWKNNFIPNALDDFTVDGKTYSVPMNLAPSSLIYY
                     NQAIFDQYGVKVPKTWDELLQAIDTFKRNNVIPIALGNKANWVVQSTTFSTIADRVTGT
                     EWFLKAVAQDGAKFTDPEFIKALTYMQELGKAGAYQDGYNSIDENQMIQLYTQGKAAMF
                     IDGGWAVASLVNTASADLLRNTHITILPPIEGGKGEPQTTAGVVGTGLGVNKKLTGAKK
                     EAALELFYALAGPDGQRATLDSSTLVSYKIDVDKTKAHPLFVELTELMKNVKIVPVYDS
                     KLSSAAVEVINNGLQDLLMGGKPEDIAKRVQDAQAGAVGK"
     PFAM_domain     complement(1465..2367)
                     /aSDomain="SBP_bac_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01547.27"
                     /description="Bacterial extracellular solute-binding
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg67_3_0002"
                     /evalue="7.00E-36"
                     /label="ctg67_3"
                     /locus_tag="ctg67_3"
                     /protein_end="356"
                     /protein_start="55"
                     /score="124.9"
                     /tool="antismash"
                     /translation="AMRKILDDFKAQHPEIDLQVEALATDGLKTRLRTAAAANEMPDLF
                     VMWPGAMTKEFVNGDLLQPIDDFLNSKPEWKNNFIPNALDDFTVDGKTYSVPMNLAPSS
                     LIYYNQAIFDQYGVKVPKTWDELLQAIDTFKRNNVIPIALGNKANWVVQSTTFSTIADR
                     VTGTEWFLKAVAQDGAKFTDPEFIKALTYMQELGKAGAYQDGYNSIDENQMIQLYTQGK
                     AAMFIDGGWAVASLVNTASADLLRNTHITILPPIEGGKGEPQTTAGVVGTGLGVNKKLT
                     GAKKEAALELFYALAGPDGQ"
     CDS             3002..3514
                     /locus_tag="ctg67_4"
                     /transl_table=11
                     /translation="MVSREQRPSFWYIFFSHHPYCQLNRTLQVSLFGKKIVLCTRCTGQ
                     YSMMLLYLILSLLFEIKEPAVLIYLLPLPATLDWLTQTIKWRESTTPIRLLTGGLFGIW
                     LAAAVRHIIFWDSQILLQLLYQSIIYIMAVLLVLIAKKGSIDDYLQPYEDFINEYQTNI
                     KPHKSVE"
     PFAM_domain     3086..3319
                     /aSDomain="DUF2085"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09858.11"
                     /description="Predicted membrane protein (DUF2085)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg67_4_0003"
                     /evalue="1.00E-14"
                     /label="ctg67_4"
                     /locus_tag="ctg67_4"
                     /protein_end="106"
                     /protein_start="28"
                     /score="54.9"
                     /tool="antismash"
                     /translation="VSLFGKKIVLCTRCTGQYSMMLLYLILSLLFEIKEPAVLIYLLPL
                     PATLDWLTQTIKWRESTTPIRLLTGGLFGIWLA"
     CDS             complement(3605..4522)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     244.9; E-value: 1.7e-74)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg67_5"
                     /transl_table=11
                     /translation="MRTIKLGTSTLEVPVIAVGCMRINSLSKSEAERFVRTALDEGANF
                     FDHADIYGGGACEEIFADAIQMNDDVREKIILQSKCGIRKGSFDFSKEHILASVDGILK
                     RLKTDYLDVLLLHRPDALVEPEEVAEAFDTLQSSGKVRHFGVSNQKPMQIELLKKYVKQ
                     PIVANQLQLSITNATMISNGINVNMENDSAIDRDGSILDYCRLHDITIQPWSPFQYGFF
                     EGVFLGNDKFPELNQKIDEIAAKYNVTNTTIAIAWLLRHPARMQPVIGTMNIERLKDCC
                     KAADVHLTREEWYEIYRAAGNVLP"
     PFAM_domain     complement(3635..4477)
                     /aSDomain="Aldo_ket_red"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00248.23"
                     /description="Aldo/keto reductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg67_5_0004"
                     /evalue="3.00E-56"
                     /label="ctg67_5"
                     /locus_tag="ctg67_5"
                     /protein_end="296"
                     /protein_start="15"
                     /score="190.7"
                     /tool="antismash"
                     /translation="IAVGCMRINSLSKSEAERFVRTALDEGANFFDHADIYGGGACEEI
                     FADAIQMNDDVREKIILQSKCGIRKGSFDFSKEHILASVDGILKRLKTDYLDVLLLHRP
                     DALVEPEEVAEAFDTLQSSGKVRHFGVSNQKPMQIELLKKYVKQPIVANQLQLSITNAT
                     MISNGINVNMENDSAIDRDGSILDYCRLHDITIQPWSPFQYGFFEGVFLGNDKFPELNQ
                     KIDEIAAKYNVTNTTIAIAWLLRHPARMQPVIGTMNIERLKDCCKAADVHLTREEWYEI
                     "
     CDS             complement(4897..5274)
                     /locus_tag="ctg67_6"
                     /transl_table=11
                     /translation="MDVRFPVTRDPGNFSEVIELDLRDVDYIETHQTGFVVFHTKDEVF
                     YPVVPKLSILEKHLEDLGFLRLDRTNLSNIEKIRYYDEERSLVFFNDKISKSSKFTTVS
                     SSMKKMLKNRLARKSGRNGNH"
     PFAM_domain     complement(4930..5229)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg67_6_0005"
                     /evalue="2.90E-08"
                     /label="ctg67_6"
                     /locus_tag="ctg67_6"
                     /protein_end="115"
                     /protein_start="15"
                     /score="33.9"
                     /tool="antismash"
                     /translation="EVIELDLRDVDYIETHQTGFVVFHTKDEVFYPVVPKLSILEKHLE
                     DLGFLRLDRTNLSNIEKIRYYDEERSLVFFNDKISKSSKFTTVSSSMKKMLKNRL"
     CDS             complement(5347..5466)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_7"
                     /sec_met_domain="TIGR04223 (E-value: 5.8e-14, bitscore:
                     41.4, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKMAAKLLSNVLNGIAVFFVKTASPMLYRPEIPEELKK"
     aSDomain        complement(5350..5460)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg67_7_0001"
                     /evalue="2.60E-11"
                     /identifier="TIGR04223"
                     /label="ctg67_7"
                     /locus_tag="ctg67_7"
                     /protein_end="39"
                     /protein_start="2"
                     /score="41.4"
                     /tool="antismash"
                     /translation="KMAAKLLSNVLNGIAVFFVKTASPMLYRPEIPEELKK"
     CDS             complement(5463..5993)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_8"
                     /sec_met_domain="AgrB (E-value: 1.5e-21, bitscore: 66.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEAIAESLAAKIKRANQEQTASIAVMKFAIIIVLNFTIPVVTSL
                     AFGAFTGKWFETITATGFFVLLRMVSGGYHLETPIPCMLLTFAVMAVPPHLTFPEPWTL
                     ILTAVAFVLVTLLAPANMKGYNTIPERYYPLLKFASMLVVSSNFLFHSQTAAIVLAIQG
                     MTLLFHNKEVNQS"
     PFAM_domain     complement(5520..5975)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg67_8_0006"
                     /evalue="2.10E-18"
                     /label="ctg67_8"
                     /locus_tag="ctg67_8"
                     /protein_end="158"
                     /protein_start="6"
                     /score="66.4"
                     /tool="antismash"
                     /translation="ESLAAKIKRANQEQTASIAVMKFAIIIVLNFTIPVVTSLAFGAFT
                     GKWFETITATGFFVLLRMVSGGYHLETPIPCMLLTFAVMAVPPHLTFPEPWTLILTAVA
                     FVLVTLLAPANMKGYNTIPERYYPLLKFASMLVVSSNFLFHSQTAAIV"
     CDS             complement(5986..6642)
                     /locus_tag="ctg67_9"
                     /transl_table=11
                     /translation="MDGLDVLAFIFFSALEWLALIVLTFAIFKFPLRGYWGRLLFSALM
                     LSFLSYLILVTLNLALYGSFIQLPIVFIYFWQLFRIPVFYAGLMVVNGYVLYTLLQAAI
                     LFVFQNAGIMVMPNVPTAFVVQTITACVAFFMAWLLVRKNMGFTFVPDTDRAKVKWTKL
                     NIRLLVMSILGYAALSMFNFLYFKGYTPLLILILGAVVFGFLQYLVFKREYYENG"
     CDS             7425..8129
                     /locus_tag="ctg67_10"
                     /transl_table=11
                     /translation="VRSKKLQALAISFALFCSFTVAGVAGAQKPDLDHPIQPKSVVKKE
                     FVPTDPEDFIKKNGLRKPSKDAVLVKVVDVDYVYENDPSAGETVHPLEIGGNEYYIKNV
                     GPEYVTYGSYVVASVEESGATNGTLTLSQAVAVANSYNVSVSVNAQIITAAVGYNVTQT
                     WTTTATYSQNVTKDNKITVIDAYDKYYQRSFEVWEDDVFYDDFVTTGTSKRHVGFRYVV
                     WEKSAGSGGGWV"
ORIGIN
        1 attgccgaac acgcagtctt taccgagctc gattccgcgg aaatcgacgg ctctggcgac
       61 atgtgttttc ttggcaatgt cggccccgac aacaagagtt gattcggtaa tttgttgaat
      121 tcgttgattc tgtttcctgg cgtgtttata cttcattgta gagtgcctcc tgcgctggga
      181 tttgttcttt ggtcggaacg ttccccagta tacagaaggt acttttttca ttcaaacctc
      241 gaattcattc attacaggaa tggctccttt ccgactaatc cgcttttctt cgggtcagcc
      301 actggctggt gccgatgaac agcaggctga tcaggacgat ggccgttgaa atggcgctgc
      361 cgtatccgta gcggtaagtc gagaacgtgg aattgtacat ataagtcgcc agcagttcgg
      421 tcgcatgggc gggaccgcct ttggtcatga cgtagacgag gtcgaacgat ttcaagctgc
      481 cggaaatgca gaggatgatc gccacctgaa tggtgcccca gatcatcggc agggtgatcg
      541 taaacagctt tctggcgccg gatacgccat cgatcttggc cgcgtcgtgg atttcgctcg
      601 ggatgttttg cagcgcggaa atgaagatga tgaggtacag cccgacgaag ttccagatga
      661 gcggaggcag cagcgcatag atcgagatgt ccggatcgga cagccactgc atcttccaag
      721 agccaagtcc caaagcgtcc agcaggaaat tcaaaatccc gatttgcggg tggtaaatat
      781 actgccagat catcccgatg accacggaag acaggaccat cggcataaag atcgaagcgc
      841 gcatgaaccg ctgcagcgcg ttgctcttgt gcagcagaat cgccagcacc aatgcgatcg
      901 gcacttggcc caatatggaa gcgaggacga agatgacatt gtttttgagc gaatgccaaa
      961 agaccgaatc gcggatcaat tcggcatagt tttgaaatcc gatatatttg gcctcgccga
     1021 tgcccgacca attaaaaaaa ctgtagtagg ccgaccaaat gaccggcacg aacacgaaca
     1081 aagcgtagag gattaccgaa ggcagcaaag ctgccgcaat aaaccggcgt acgcgggatg
     1141 cattcaattc gatcacttcc ttgacgtaat cagccctcct ggaaggaggg ctgtttcggg
     1201 aaccgcttgc gcttacttac cgactgcgcc ggcttgagcg tcctgaactc tcttggcaat
     1261 gtcttccggt ttgccgccca tgagcagatc ttgaaggccg ttgttgatca cttcgactgc
     1321 cgcggagcta agcttggagt cgtaaaccgg cacgatcttc acgttcttca tcagctcggt
     1381 cagctcgacg aacagcggat gagctttggt tttatcgacg tcgattttgt agctaaccag
     1441 cgtgctgctg tccagcgtcg ctctttggcc gtcgggtccg gccagcgcat agaacagctc
     1501 caatgccgct tctttcttcg cacccgtcag tttcttgttg acgcccagac ccgtaccgac
     1561 aacgccggcg gtcgtttggg gctcgccttt tccgccttcg atcggaggca gaatcgtaat
     1621 atgcgtgttc ctcaaaaggt ccgccgaagc agtgttcacc aagcttgcca cggcccagcc
     1681 gccatcgatg aacatcgccg ctttgccttg cgtatagagc tggatcattt ggttttcgtc
     1741 gatgctgttg tagccgtctt gataagcgcc ggctttgccc aattcttgca tataggtaag
     1801 agccttaatg aattccggat ccgtaaattt cgccccgtct tgcgcaacgg ctttcaggaa
     1861 ccattccgta ccggttacgc ggtcggcgat ggtgctgaag gtcgtggatt ggacaaccca
     1921 gttcgctttg tttccaagcg cgatcggaat gacgttgttc cgtttgaagg tatcgatggc
     1981 ttgcagcagc tcgtcccagg tcttaggaac ctttacgccg tattgatcga agatcgcctg
     2041 gttgtaataa attagggagc taggcgccag gttcatcgga accgagtacg ttttgccgtc
     2101 taccgtaaaa tcgtccaacg cgtttggaat aaagttgttt ttccattccg gcttgctgtt
     2161 caggaagtcg tcaatcggct gcagaagatc gccgtttacg aattccttgg tcatggcgcc
     2221 cggccacata acgaacaggt ccggcatttc atttgcggca gccgccgtgc gcaggcgcgt
     2281 tttcaaccca tcggtcgcaa gcgcttccac ctgaaggtcg atttcagggt gctgcgcttt
     2341 aaaatcatcc aggatttttc tcatcgcgac cgctttggca tcttggccgg accagttgtt
     2401 ccaaagcgtc agcgttattt tttcctgttt gccgccggac gcgtcgttgt ctgcagattg
     2461 tccgccgccg caaccagcca gcagagacac gcagaccgct atcgctaagg cgagtatgaa
     2521 gcgttttttc atggatgtaa ccctcccctg tttatgtcca cgttcattct atatgggatg
     2581 tttcattccc gtaaggggaa gatgataagg accagggggg aaaaagatcg gatcgcgtgg
     2641 tgcgcggagg ctttcagcgc ggagaaatag agaggatcta agtactacaa aaaccaacaa
     2701 aaatgtagta acaaatacct aaaaattcag cgcatcaatg ttgatataag gagaaatatg
     2761 gaattaaatc tcgaataatg tatgtatcta atgaacaaaa ggggaataat gcatggctga
     2821 aattaggtat tgtgaactat gcaatcgaaa tgtagaacct actaaaaaat tcaattggct
     2881 tgtcttcatt tttctatgcg gactctttta tctgctttac tacccgttta aatcgaagag
     2941 atgccccatc tgcggcacaa cacatctttc ggctccaaga cccatgcatc atctataatt
     3001 tatggttagc agagagcaga gaccgagttt ttggtacata tttttttctc atcatcctta
     3061 ttgccagttg aataggacac tacaggtatc gttattcggg aaaaaaattg ttctatgcac
     3121 tcgttgcact ggccaataca gcatgatgct actttatttg attttgagtt tattatttga
     3181 aataaaagaa cctgctgtat tgatctatct ccttccttta ccggcaacct tagattggtt
     3241 gacgcaaacg attaaatggc gggaatcgac aacgccaatc cgcttgctta cgggaggact
     3301 ttttggtatt tggctagctg cggccgttag acatatcatt ttttgggatt cacaaatact
     3361 tcttcaatta ctttatcaaa gcatcatcta cattatggct gttttgttgg ttcttattgc
     3421 gaaaaaaggc tctattgatg attacttgca gccatacgag gactttatca acgaatatca
     3481 aaccaatatc aaacctcaca aatctgttga ataggatgta gtcaaaccta tactttaccc
     3541 cacttcgatt tcatttaaga agccgacctc acatggtcgg cttttttcgt accgcttttc
     3601 tcccttacgg caacacgttg cctgccgcac ggtaaatttc gtaccattct tcgcgggtca
     3661 gatgaacgtc ggcggccttg cagcaatctt tcaaccgttc aatattcatc gtgccgatca
     3721 ccggctgcat gcgggccgga tggcgcagca gccacgcgat cgcgatcgtc gtgttggtca
     3781 cgttgtattt ggcggcgatt tcgtcgattt tctgattcag ttcggggaac ttgtcgttgc
     3841 cgagaaatac cccttcaaaa aatccgtatt ggaacggcga ccaaggctga atcgtgatgt
     3901 cgtgcagacg gcaatagtcg aggatgcttc cgtcgcggtc gatcgcggaa tcgttctcca
     3961 tattgacgtt aatgccgttg gaaatcatcg tggcgttggt aatgctgagt tgcagctggt
     4021 tggcaacgat cggctgcttg acgtactttt tcaacagttc gatctgcatc ggtttttggt
     4081 tggatacgcc aaaatggcgt actttccccg agctttgcag agtgtcgaac gcttcggcca
     4141 cctcttcggg ctcaaccagc gcatcgggac ggtgcaggag cagcacatcg agatagtcgg
     4201 tcttcagccg cttcaggatg ccgtccacgg acgccagaat atgctccttg gaaaaatcga
     4261 agctgccctt gcgaatgccg cacttggatt gaaggatgat cttctcgcga acgtcatcgt
     4321 tcatctgaat cgcgtcggca aagatttcct cgcaggcccc gccgccgtaa atatcggcat
     4381 gatcgaagaa attcgcccct tcgtccagcg ccgttcgcac aaaacgctcc gcctcggatt
     4441 tactcagcga attaatccgc atgcagccga ccgctataac agggacttca agcgtgctgg
     4501 ttcccagttt gatcgttctc atgataaacg tcacttcctt cgttaaatta gatgcgaccg
     4561 gtttcgcagg aaaaaagatg cgcaatatgt aagcggtaac accaaatcgc tgcgcaaaac
     4621 ggtgaatccc tatattattg tgacatagaa gtatggaagc tttcaaggct gatggtgttt
     4681 tttagtagac acctatgctc ctatgacgct ggcgaagtgc tatcagggag ggaacgtgcg
     4741 actatcctgg tttttttcaa tttacagcgc catcctaaga accggatgtt ttcctatatt
     4801 ccatgcatac agcatgtgca taaacaaaaa atccaccctt ggatcaggca gatttccatt
     4861 tctaatgtcg gctaaccgtc tccatcccgg ggcagttcaa tgattcccgt ttctgccgct
     4921 cttgcgggca aggcgatttt ttagcatttt tttcatactg gatgatacgg tggtaaattt
     4981 gcttgatttt gaaatcttgt cgttaaaaaa aacgagcgat cgctcttcat cgtaataccg
     5041 gatcttctcg atgttgctca gattcgttcg atccaaacgg agaaagccca ggtcttcaag
     5101 atgtttttcc agaatggata atttaggaac tacgggataa aaaacttcat ccttggtgtg
     5161 aaacacgaca aagcccgtct gatgcgtttc aatatagtcg acatctctca aatcgagttc
     5221 gataacctcc gaaaaattgc cggggtctct tgtcaccggg aaacgcacat ccattcaact
     5281 ccaaaaccgg cagacaaggg ctgcccgatg aaatgacccg tatgacagcc cttgatgtcg
     5341 agtgggttac tttttcagtt cttcagggat ctcgggacgg taaagcatgg gagaagcagt
     5401 tttcacaaaa aaaacagcaa ttccattcaa cacgttagac agtaatttgg ctgccatttt
     5461 cctcatgatt ggttcacctc cttgttgtgg aacaataagg tcatcccttg aattgccagc
     5521 acaatggccg ccgtttgcga atgaaacagg aaattgctag aaacaaccag cattgaagca
     5581 aatttcagca aaggatagta cctttcaggt atcgtgttat agcctttcat attggcggga
     5641 gctagcagtg tcacaaggac aaaggcaacc gctgttaaaa tcaaggtcca tggttcggga
     5701 aaagtcaagt gtggtggaac ggccataacc gcgaaggtca gcagcataca tgggatcggt
     5761 gtctccaaat ggtacccgcc tgataccata cgaagcaaaa cgaaaaagcc agtcgccgta
     5821 atggtctcga accatttccc tgtgaatgca ccgaatgcta gcgaagtgac aaccggaatc
     5881 gtgaaattaa ggacaataat aatcgcaaat ttcattacag caatacttgc tgtttgttcc
     5941 tgattagccc ttttgatttt tgctgccaaa ctctcggcta tcgcttcaac cattttcgta
     6001 atactccctt ttgaacacca aatactgaag aaacccaaaa acgacagcac caagaatcag
     6061 aataagcaac ggggtgtatc ctttaaaata taaaaagtta aacatggaga gagcggcata
     6121 tcctaaaatg ctcataacaa gtagtcgaat attgagcttg gtccatttca ccttggcacg
     6181 atccgtatcg ggcacaaacg taaagcccat gttctttcga accaataacc aagccatgaa
     6241 gaaggcaacg caggcggtta tcgtttggac gacaaatgct gttggaacgt taggcattac
     6301 cataattccg gcattttgaa atacgaaaag gatcgcggcc tgaagcaacg tgtacaacac
     6361 gtaaccatta acgaccatca gccccgcata gaaaaccgga atccgaaata attgccagaa
     6421 ataaatgaat acgatgggca gttgaatgaa cgatccatac aaagccaaat tcaatgttac
     6481 caaaatcaga taggatagga acgatagcat taaagcagaa aacaaaagcc ggccccaata
     6541 gccgcgcaac ggaaatttga aaatggcaaa cgtgagtacg atcaaggcca gccactcgag
     6601 tgccgaaaag aaaataaagg ccaaaacgtc caagccgtcc atttcgactc tccttgcttc
     6661 gcgattcatg ccttaaatac gcggagtaac atatttcgcc aatgatcacg ataaatcctt
     6721 cttttttccc actttattaa acataaattt cgtatgaaat gaaaaaagca ctataccgat
     6781 atttatgacc atctacctga aaacaatagt acgaatcata aatgcatgga ttacaagatg
     6841 caacccgaat ctcgtccaat atacctgaat tgcgactaat ggtgttattt tccttaaaat
     6901 acattgtagg ttgtttttag ttgcttagct ggccactatg aacggacggg acaatttaaa
     6961 agaaaaaacc cgctcctccc cggcgaggac cggtcaaagg actttgacgt acgttgattc
     7021 caagcaatcg actaaagaaa gtagaagcct acgataacgg cgatgacgcc tccgcttctg
     7081 atgatgataa gtgcaacttg gcttggctcg gtacctttat actgccatcc atactgtaag
     7141 taccagaaga atttcgggaa aaggatattg atgataccta agatgataaa aaggaaagct
     7201 acagttttaa aaaggttcat atgttttcac ccattttcaa attcttttgt tatgagttta
     7261 catttgattc caattgaata agtattaagc ggtgcttact gattataaag atatgctaaa
     7321 atttataaag aattccgttt tgcttatttc caaatataag caattatggt accatattaa
     7381 cggaaattgg ccaatatcca aaaaaatgtg aggaggctag tatagtgaga agtaaaaagt
     7441 tgcaagcatt ggcaatatca ttcgctttat tctgttcttt tactgtcgca ggggttgcgg
     7501 gagcacaaaa gccggatcta gatcacccta tacaacccaa aagtgtcgtg aagaaggaat
     7561 ttgtacctac ggaccctgaa gattttatca aaaagaacgg tctcaggaaa ccttcgaaag
     7621 atgcagttct tgtaaaagtt gttgacgtag attatgttta tgagaatgat ccatctgcag
     7681 gtgaaactgt tcatcccttg gaaataggag ggaacgaata ctatattaag aatgtaggtc
     7741 cggaatatgt aacgtatggc tcatatgttg ttgcgtctgt agaggagtcg ggtgccacaa
     7801 atggaacgtt gactctttcg caagcagtag cagttgccaa ttcatacaac gtgagtgttt
     7861 cggtcaatgc gcaaatcatt actgcagcgg ttggatataa tgtaacacaa acatggacta
     7921 caacagcaac atattcgcaa aatgttacca aagataataa aattactgta attgatgcct
     7981 atgataaata ttaccaaaga agtttcgaag tttgggaaga tgatgttttt tacgatgatt
     8041 ttgtaacaac aggaacatct aaacgtcacg tcggatttag atatgttgta tgggagaaat
     8101 cagctggttc cggtggcggt tgggtataat cgaatataga catagctatt ggctccccat
     8161 gtctcttcga agcgatccag ttccacaagt gccatttctt ccgtcgcagc tttgtaaatg
     8221 ggctttaggt ccgccgttac ttttttgagg tccttgtagg acacttagcg cgtcgaattg
     8281 cggatttggt gaatgatgca cttctgaatc tcggtcttcg ggtagctaca gactccggcg
     8341 tagccgaaga ggacctcgtt aaactccggc aaaagggact cgaggtggtt gttgcttagc
     8401 gggatcgaac ttttcggctc ttgcccttcc cggtgggagg aggaaagggc gttgtttatg
     8461 ttctggggat cgagtaggag ggggcggcta acccccgtcc tctcacaaca cctagcatgc
     8521 gggtccgcac taggcgtttc caaaaggttg acaaagttcc agataacgag aaagcaaact
     8581 tttcagccct tttgcttccc aataggaagt tggaagggcg ttgtttatgg ttcgggacat
     8641 ttcccaagga cctcgtctag aattggccat catgaagacc atccaatcgg gcatgccaag
     8701 cgcccggagt tcgcggatgc gggttcgtac ccgtttccac tgtttccatt ggcacatgcg
     8761 aagccttct
//
