LOCUS       c00001_NZ_ARWH..        9775 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_ARWH01000001.1 Methyloversatilis universalis Fam500
            Metunv3DRAFT_Contig245.1_C, whole genome shotgun sequence.
ACCESSION   NZ_ARWH01000001
VERSION     NZ_ARWH01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:54:53
            Original ID  :: NZ_ARWH01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1055688
            Orig. end    :: 1065463
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..258)
                     /locus_tag="ctg1_957"
                     /transl_table=11
                     /translation="MNVQFPGPAVPMQDGGISYRATVDGVTVACQFTWEALQDVNPEFT
                     LDQPINQFNFSAERLLAIAEKKIRNGGIVNGVVLVNTGDL"
     protocluster    1..9775
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1059821:1060670](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(4134..4982)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..9775
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9775
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="3"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(592..1998)
                     /locus_tag="ctg1_958"
                     /transl_table=11
                     /translation="MSVQRIKIPRVADRKIAETFTELGKKFATTHAHVNALAFSDIGQI
                     NLTGEPVGDWKVLLDHDSSLIESMGCSIGGLTISYARGGQYPSEQKSPIFDEIVLNWHN
                     QGTPTTAQKLDIVAFINSRLHPFEPGRVIGSGVSEEQAQLLAIHQSTLDRLERLNEDLI
                     RQSSEFRKGLEEKFEEKAAQVDAEYAEKKKRLEVDGQALTAQVEAKERALDEKLKAIDD
                     RDNTHVRREIRDRMLDDVKKRISQFGVSRFTSDKRRPVLVGIILLLAVFVGLLGWTGYE
                     INAMDNQYSSMLEAIKNISAWGPEKIKAAGLGADVVAHVSATDVDRTHLFWLWGRFTLF
                     SLGLVGTILYYIKWQNRWAEQHIISEFNLQQFYIDVNRANWVIESCLEWRKVTESAIPK
                     ELLGSITTGLFVNNQTEPERVIHPADELASALLGTASKLKLKVGGSELDFDKPKKIPNK
                     PIKVGVPHDE"
     misc_feature    complement(1201..1203)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             2365..3336
                     /locus_tag="ctg1_959"
                     /transl_table=11
                     /translation="MKTRITELLGIRYPIVQGGMMWVGRAELASAVSNAGGLGILTALT
                     QPTPEALTAEIARCRDMTDQPFGVNLTILPAIKPPPYEAYLDAMLDAGIRIIETAGNNP
                     EAFIAKAKVRGATIIHKCVAVRHALSAQKKGVDIVSIDGFECAGHPGEDDVPGLVLIPI
                     AARALDIPVIASGGIGDGRGMAAALALGAEGVNMGTRFCVTKEAPIHDSIKQALVKASE
                     RDTRLILRSLHNTARVFRNAVSDAVVEAESRGCTFEDIRPLVSGARGAAALAEGDIDGG
                     VVTAGQVIGLIDDIPGCAELIERMVADCRAALKAAAEKAAGD"
     PFAM_domain     2371..3288
                     /aSDomain="NMO"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03060.17"
                     /description="Nitronate monooxygenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_959_0130"
                     /evalue="2.50E-60"
                     /label="ctg1_959"
                     /locus_tag="ctg1_959"
                     /protein_end="308"
                     /protein_start="2"
                     /score="204.7"
                     /tool="antismash"
                     /translation="TRITELLGIRYPIVQGGMMWVGRAELASAVSNAGGLGILTALTQP
                     TPEALTAEIARCRDMTDQPFGVNLTILPAIKPPPYEAYLDAMLDAGIRIIETAGNNPEA
                     FIAKAKVRGATIIHKCVAVRHALSAQKKGVDIVSIDGFECAGHPGEDDVPGLVLIPIAA
                     RALDIPVIASGGIGDGRGMAAALALGAEGVNMGTRFCVTKEAPIHDSIKQALVKASERD
                     TRLILRSLHNTARVFRNAVSDAVVEAESRGCTFEDIRPLVSGARGAAALAEGDIDGGVV
                     TAGQVIGLIDDIPGCAELIERMVAD"
     CDS             complement(3352..4137)
                     /locus_tag="ctg1_960"
                     /transl_table=11
                     /translation="MSALAELQRQFMHYLHDAPNAFIDTLAASDGLAPAARAHIYHNAY
                     RVRLLDTLKDSFDKTWAWLGDEAFESAGRRYIAAQPPTQFSLRPFGDRFPAWLQSAWPE
                     DPEVAELAALDWALRDAFDSADGAALDAAALAAYSAEDWGRIVFALQPGAQWLQFSRNT
                     LDLWHAMDRGDPPPALVTLAQPLTVLAWRKGEQPHFRSVDAPEAVMLRAMQAGTPFAAA
                     CACVDAPDAQTLIGGWLARWLADGLIREADCPAPPADPG"
     PFAM_domain     complement(3844..4122)
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_960_0131"
                     /evalue="4.40E-19"
                     /label="ctg1_960"
                     /locus_tag="ctg1_960"
                     /protein_end="98"
                     /protein_start="5"
                     /score="68.6"
                     /tool="antismash"
                     /translation="ELQRQFMHYLHDAPNAFIDTLAASDGLAPAARAHIYHNAYRVRLL
                     DTLKDSFDKTWAWLGDEAFESAGRRYIAAQPPTQFSLRPFGDRFPAWL"
     CDS             complement(4134..4982)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_961"
                     /sec_met_domain="DUF692 (E-value: 6e-99, bitscore: 328.4,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLTAPSPGFGLGLRPAHYAALLETRAPLEWLEIISENFMVDGG
                     KPMAMLDRLRADYPMALHGVALSIGSTDALDRNYLKKLKALADRVDPLWISDHFCWTGV
                     GGHTSHDLLPLPYTAEAVRLLVSRIGQVQHELGRRLVLENVSSYLGYAVSDMTEWDFIR
                     TVAEEADCLLLLDVNNVYVSSVNHGFDPLDYLAGIPAARVQQIHLAGHSTHDDHLVDTH
                     DQPVCEAVWALYEHACRLFGDVATMIERDDNIPDLPDLLTELARARRIAAQAVTAEQVA
                     A"
     PFAM_domain     complement(4170..4955)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_961_0132"
                     /evalue="1.30E-107"
                     /label="ctg1_961"
                     /locus_tag="ctg1_961"
                     /protein_end="271"
                     /protein_start="9"
                     /score="359.1"
                     /tool="antismash"
                     /translation="GFGLGLRPAHYAALLETRAPLEWLEIISENFMVDGGKPMAMLDRL
                     RADYPMALHGVALSIGSTDALDRNYLKKLKALADRVDPLWISDHFCWTGVGGHTSHDLL
                     PLPYTAEAVRLLVSRIGQVQHELGRRLVLENVSSYLGYAVSDMTEWDFIRTVAEEADCL
                     LLLDVNNVYVSSVNHGFDPLDYLAGIPAARVQQIHLAGHSTHDDHLVDTHDQPVCEAVW
                     ALYEHACRLFGDVATMIERDDNIPDLPDLLTELARARRIA"
     CDS             complement(5049..5339)
                     /locus_tag="ctg1_962"
                     /transl_table=11
                     /translation="MSTNTFGASIAAAAALLALSGTVFAADMPAGSKGAAVGAGDKVHC
                     YGLHACKGNSDCATTEHSCKGQNACKGHGFKATSAKQCLEQGGTIGDLSAK"
     CDS             complement(5547..6791)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 127.1; E-value: 1.9e-38)"
                     /gene_kind="other"
                     /locus_tag="ctg1_963"
                     /transl_table=11
                     /translation="MSDEFPGGAPVPIRPMDEISVPVALDGHDGVNRADRARLQIGADT
                     DMDAIRCFLTEYDRSPGTHRIYQRECERLLLWSLVECGKPLSSLNRQDFEGYLNFLVDP
                     QPAKLWCGPKVQRVRAEWRPFVGPLSESAVLTAIAAINSLMAYLVDAGYLAGNPLGLIR
                     QRRRKLAAQNAGPAHVIAQTEEMQKIERFLDAEMWQAVTRAIEAMPRDTDGERDEYERA
                     RFIAALLYMLAPRAGELESHRMNSFREERGRWWWHVVGKGGKQAKVPVADDMVHALVRY
                     RKHLGLPAMPKRTDLTPLLVSLKDRSPITSRRLNQILKKIFYAAAELLPEESEYKKDKL
                     RAASAHWGRHTGITAKLDAGMSERYVQKDARHTDARTTQRYIHEEEERWHDEAQKQQLP
                     WVVPDGPDASTPGSK"
     PFAM_domain     complement(5637..6143)
                     /aSDomain="Phage_integrase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00589.24"
                     /description="Phage integrase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_963_0133"
                     /evalue="2.40E-12"
                     /label="ctg1_963"
                     /locus_tag="ctg1_963"
                     /protein_end="385"
                     /protein_start="216"
                     /score="47.1"
                     /tool="antismash"
                     /translation="DEYERARFIAALLYMLAPRAGELESHRMNSFREERGRWWWHVVGK
                     GGKQAKVPVADDMVHALVRYRKHLGLPAMPKRTDLTPLLVSLKDRSPITSRRLNQILKK
                     IFYAAAELLPEESEYKKDKLRAASAHWGRHTGITAKLDAGMSERYVQKDARHTDARTTQ
                     RYIHEE"
     CDS             6881..9775
                     /locus_tag="ctg1_964"
                     /transl_table=11
                     /translation="MAAGRARTRKQVSFAAPAHDRPRIVCMNLLATVVLLPLLAGTSAC
                     ALIGRGNTPARRLLTALAAGGVTLAALALLLRMAPAVFAGEVPAAGFEWLPQLGLNIGW
                     RLDGLALMFGLLITGIGALIVLYAHHYLGSEDPAGKFYALLMLFMAAMLGVVLSDNLLM
                     LVVFWELTSVSSFLLVGYWGHRADARAGARMALAVTGGGGLVMLAGFVLLGQIAGSYEL
                     TEILQHRERIVADPLYPLVLALVLTGCFTKSAQLPFHFWLPEAMAAPTPVSAYLHSATM
                     VKAGIFLMLRLYPVLGGTALFEQVVTGFGLATVTFAAWVAIFRHDLKGLLAYSTVSHLG
                     FITVLIGLDAPMAKVAAVFHILNHATFKAALFMSAGIVDHACHSRDLRRLGGLYGWMPW
                     TATFALTAAAAMGGLPPLNGFLSKEMYFAEALAGADRLSWIVPAVALLAAVSSMAYSLR
                     FAHDTFFNGPTRDLPADAHPHDPPAGMLAPVALLALLCVAVGLFPESTYGPLVRLAADA
                     ALGGPPPEFHLALWHGVNGPLAMSAVAVLAGFALYAGLMKGRALHGYLPRAWSGKLAFG
                     CAIDRLFAFAGRVTAATENGSLQRSLLIMVAFAVLLAAAPFWQADALPAAGDRTLMPAT
                     PLALALWALLLITATVIAATHHQRFRALVLVGIVGLITALTFVGLSAPDLALTQLSVEV
                     VSTVLMLMGLALLPQHTPRESSALRRGRDALLALVAGGGVAGLTWLMLTRNHDSISWFF
                     LERSLTEGGGNNVVNVILVDFRGYDTFGEITVLGIAGLGALALLDGFRTRRPAADADGR
                     AWAFEQQPLLLRVAARVVLPLALLASAYIYWRGHNMPGGGFIAGLMTSVALVMQYMALG
                     QARAESLLHGAAGRRFTRWIGTGLGIAGLTGIGAFWFGRPFLTSAHGHPALPVIGELPL
                     ASAAAFDLGVYITVVGATLLTLSVLGAASKEDHA"
     PFAM_domain     7166..7306
                     /aSDomain="Proton_antipo_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00662.22"
                     /description="NADH-Ubiquinone oxidoreductase (complex I),
                     chain 5 N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_964_0134"
                     /evalue="2.30E-07"
                     /label="ctg1_964"
                     /locus_tag="ctg1_964"
                     /protein_end="142"
                     /protein_start="95"
                     /score="30.8"
                     /tool="antismash"
                     /translation="PQLGLNIGWRLDGLALMFGLLITGIGALIVLYAHHYLGSEDPAGK
                     FY"
     PFAM_domain     7352..8185
                     /aSDomain="Proton_antipo_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00361.22"
                     /description="Proton-conducting membrane transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_964_0135"
                     /evalue="1.80E-59"
                     /label="ctg1_964"
                     /locus_tag="ctg1_964"
                     /protein_end="435"
                     /protein_start="157"
                     /score="201.4"
                     /tool="antismash"
                     /translation="SDNLLMLVVFWELTSVSSFLLVGYWGHRADARAGARMALAVTGGG
                     GLVMLAGFVLLGQIAGSYELTEILQHRERIVADPLYPLVLALVLTGCFTKSAQLPFHFW
                     LPEAMAAPTPVSAYLHSATMVKAGIFLMLRLYPVLGGTALFEQVVTGFGLATVTFAAWV
                     AIFRHDLKGLLAYSTVSHLGFITVLIGLDAPMAKVAAVFHILNHATFKAALFMSAGIVD
                     HACHSRDLRRLGGLYGWMPWTATFALTAAAAMGGLPPLNGFLSKEMYFAEALAGAD"
     PFAM_domain     8810..9007
                     /aSDomain="DUF4040"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13244.8"
                     /description="Domain of unknown function (DUF4040)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_964_0136"
                     /evalue="2.80E-18"
                     /label="ctg1_964"
                     /locus_tag="ctg1_964"
                     /protein_end="709"
                     /protein_start="643"
                     /score="65.9"
                     /tool="antismash"
                     /translation="LLLITATVIAATHHQRFRALVLVGIVGLITALTFVGLSAPDLALT
                     QLSVEVVSTVLMLMGLALLPQ"
     PFAM_domain     9347..9727
                     /aSDomain="MnhB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04039.15"
                     /description="Domain related to MnhB subunit of Na+/H+
                     antiporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_964_0137"
                     /evalue="5.10E-30"
                     /label="ctg1_964"
                     /locus_tag="ctg1_964"
                     /protein_end="949"
                     /protein_start="822"
                     /score="104.4"
                     /tool="antismash"
                     /translation="LRVAARVVLPLALLASAYIYWRGHNMPGGGFIAGLMTSVALVMQY
                     MALGQARAESLLHGAAGRRFTRWIGTGLGIAGLTGIGAFWFGRPFLTSAHGHPALPVIG
                     ELPLASAAAFDLGVYITVVGATL"
ORIGIN
        1 ctaaaggtcg cctgtattga cgagtacgac tccattcaca atgcctccat tgcgaatctt
       61 cttttccgca atcgcgagga gccgctctgc actaaagtta aattggttga tcggttgatc
      121 tagggtgaac tccggattga cgtcttggag ggcttcccag gtgaactgac aagcaaccgt
      181 cacgccgtcg acggtcgcgc gataagaaat tcctccgtcc tgcatgggaa cggcaggacc
      241 tggaaattga acgttcatct gtttcctcct ttgtgaaatc tgtcttctta tcgaccgcgc
      301 aaaccccgga tttcatgcgt cgctggcggt ggcctcattg aacctaacgt ggaagctagg
      361 agcagccgga gcacggaggg cacagaaggg ttaccgaccg attgtatttc tctgcatcca
      421 tggcgaactc ccatgagtga gtgggcgcat agcgttcaag gtcaggagcg aaataggggg
      481 cagaccacga ttatgttgcc ccaccggtaa ttcagatttc tgaagacgtg gtccgcacct
      541 attgttcagc ctgtcccttg ttgttcttca tttccttatc tccgcacagg attattcatc
      601 atggggcact cctaccttga ttggtttgtt cgggattttc ttcggtttgt cgaaatcgag
      661 ctcgctacca ccgaccttga gcttcagctt tgacgccgta cccaatagcg ccgacgcgag
      721 ttcgtctgcg gggtggatga cacgctctgg ctccgtctgg ttgttcacaa aaagcccggt
      781 tgtaatgctc ccgagcagtt ccttaggaat ggccgactcc gtcacctttc gccactccag
      841 gcaactttca atgacccagt tggccctgtt gacgtcgata tagaattgct gaaggttaaa
      901 ctccgaaatg atgtgctgtt cagcccatct gttctgccac ttgatgtagt agagaatcgt
      961 gccgacaagc cctagtgaga agagggtgaa tctgccccac agccagaata gatgagtgcg
     1021 gtccacatcg gtagcggaga cgtgagcaac gacgtccgcg ccgagcccag ccgcttttat
     1081 cttttccggc ccccatgccg atatgttctt tattgcttca agcatgctgg agtactggtt
     1141 gtccatggcg ttgatttcgt atccagtcca gcccaacagt ccgacgaata cagccaatag
     1201 taaaataatt cccacaagaa ccgggcgccg cttatctgat gtgaacctgg aaacgccgaa
     1261 ttgactgatc cgtttcttga cgtcgtcaag cattcgatcg cgaatctcac gccggacatg
     1321 ggtgttgtct cgatcatcaa tggccttcag cttctcgtcg agtgcccgct ctttagcttc
     1381 gacctgagcg gtaagtgctt gcccatcaac ttcgagacgc ttcttcttct cagcatactc
     1441 agcatcgact tgcgctgctt tctcttcaaa tttctcttct aggcccttcc gaaactcgga
     1501 gctttgtcga ataaggtctt cattcaacct ctcaagtcga tcaagcgtgc tttggtggat
     1561 cgccaagagt tgtgcctgct cctctgagac cccagatccg attactcgac cgggttcgaa
     1621 tggatgcagt cggctattta taaaagcgac gatgtcgagc ttttgtgcgg ttgttggagt
     1681 cccttgattg tgccaattta gaacaatttc atcgaagatc ggcgactttt gctcagacgg
     1741 atactggcct ccccgagcgt acgaaatagt aagcccgcca atcgagcagc ccatcgattc
     1801 gatcaaactt gaatcgtggt ccagcagaac cttccaatcg ccgactggtt ccccggttag
     1861 gttaatctgg ccaatgtcgc taaatgccaa cgcgttcaca tgggcgtggg ttgttgcaaa
     1921 tttttttcca agctcggtaa acgtctcagc gatttttctg tcggcgacgc gaggaatctt
     1981 aatgcgctga acgctcatgg acggcctcaa tgaaaatgga atggtgaagc ataaaatgat
     2041 gtgtgcgagg gtttcatcgt gtacgaaggg ctctgtttcg ataaatggag aaaccggaca
     2101 ctggtctccc tcatatattc aaaacatcgc attcgatttt ctgcttaaga aagaaaccgt
     2161 gaaactggac atatggttct cgcttcccga tcctgccttc tcttttggca gcgagcactt
     2221 tttacttcat gcgtgcacgc gactataccg cgtgcatctc cgtcagaccc atcggccgtt
     2281 ttcccgagca caccgtttga aacgccccgt ctccacccca ctggcgcatc atcaccccct
     2341 gttccccgtc accggacgca aggcatgaaa acgcgcatca ccgaacttct gggcatccgc
     2401 taccccattg tgcagggcgg gatgatgtgg gtggggcggg cggagctggc ttctgcggtg
     2461 tcgaatgccg gcgggctggg cattcttacc gcgctgacgc agccgacgcc tgaggcgctg
     2521 acggcggaga ttgcgcgctg tcgtgacatg acggatcagc ctttcggcgt gaatctgacg
     2581 atactgccgg cgatcaagcc gccgccttac gaggcctatc tcgacgcgat gctggatgcg
     2641 ggcatccgca tcatcgaaac cgcgggcaac aatccggagg cgttcatcgc caaggcgaag
     2701 gtgcgcgggg cgacgatcat ccacaagtgc gttgcggtgc ggcatgcgct gtcggcgcag
     2761 aaaaagggcg tggatatcgt gagcatcgac ggcttcgagt gtgccgggca cccgggtgag
     2821 gacgacgtgc cgggcctggt gctgattccg atcgcggcgc gggcgctgga cattccggtg
     2881 atcgcgtccg gcggcatcgg cgacggccgc ggcatggcag cggcgctggc gctgggcgcc
     2941 gagggcgtga acatgggcac gcgcttctgc gtgacgaagg aggcgcctat ccacgacagc
     3001 atcaagcagg cgctggtgaa ggcgagcgag cgcgacacgc ggctcatcct gcgcagcctg
     3061 cacaacacgg cgcgcgtgtt ccgcaacgcg gtgtcggacg cggtggtcga ggcggaaagc
     3121 cgcggctgca cctttgagga catccgcccg ctggtgagcg gggcgcgcgg tgcggcggcg
     3181 ctggccgagg gcgatatcga tggcggtgtg gtgaccgccg gtcaggtgat cgggctgatc
     3241 gacgacattc cgggctgcgc ggagctgatc gaacgcatgg tggcggactg ccgcgcggcg
     3301 ctgaaagccg ctgctgaaaa ggcggccggc gactgaggcc ggcgggcccg ctcagcccgg
     3361 gtcggcaggc ggcgccgggc agtcggcttc gcggatgagc ccgtcggcca gccagcgcgc
     3421 cagccagccg ccgatcagcg tctgcgcgtc cggcgcatcc acgcaggcgc aggcggcggc
     3481 gaagggcgtg ccggcctgca tcgcacgcag catgacggct tccggcgcgt cgaccgagcg
     3541 gaaatgcggc tgttcgccct tgcgccacgc cagcacggtg agcggctgcg ccagcgtcac
     3601 gagagcgggc ggcgggtcgc cgcggtccat cgcgtgccac agatccagcg tgttgcggct
     3661 gaactgcagc cactgcgcgc ccggctgcag cgcgaacacg atgcggcccc agtcttcggc
     3721 gctgtaggcc gccagcgcgg cggcatcgag cgctgcgccg tcggcgctgt cgaaggcgtc
     3781 gcgcaacgcc cagtcgagcg cggccagttc ggccacttcc gggtcttccg gccatgcgct
     3841 ctgcagccac gcggggaagc ggtcgccgaa aggccgcagg ctgaactgcg tgggcggttg
     3901 ggccgcgatg tagcgccggc cggccgactc gaaggcctcg tcgcccagcc aggcccaggt
     3961 cttgtcgaaa ctgtctttca gcgtgtcgag cagacgcacc cggtaggcgt tgtgatagat
     4021 gtgcgcccgc gcggccggcg ccagcccgtc gctcgcggcc agcgtgtcga tgaaggcgtt
     4081 cggcgcgtca tgcaggtaat gcatgaactg ccgctgcagt tcggccagcg cgctcatgcg
     4141 gccacctgtt cggcggtgac ggcctgcgcg gcgatgcggc gggcgcgggc gagttctgtg
     4201 agcaggtcgg gcagatccgg gatgttgtcg tcgcgctcta tcatcgtggc gacgtcgccg
     4261 aacaggcggc aggcgtgctc atacagcgcc cacactgctt cgcacaccgg ctggtcatgg
     4321 gtgtcgacca gatggtcgtc gtgggtcgag tggccggcga gatggatctg ctgcacccgc
     4381 gcggcaggaa tgccggccag atagtcgagc gggtcgaagc cgtgattgac gctgctgaca
     4441 tagacgttgt tcacgtcgag cagcagcagg cagtccgcct cttcggccac ggtgcggatg
     4501 aagtcccact cggtcatgtc ggacaccgcg tagccgaggt agctggatac gttttccagc
     4561 accagccggc ggccgagttc gtgctgcacc tgaccgatgc ggctcaccag caggcgcacc
     4621 gcctctgcgg tatagggcag cggcagcagg tcatgagaag tgtggccgcc gacgccggtc
     4681 cagcagaagt ggtcggaaat ccacagcgga tcgacccggt ctgccagcgc tttcagcttc
     4741 ttcaggtagt tgcggtcgag cgcgtcggtc gagccgatgg acagcgccac gccgtgcagg
     4801 gccatcgggt agtcggcgcg caggcggtcc agcatggcca tcggcttgcc gccgtcgacc
     4861 atgaagtttt cggaaatgat ttccagccac tcgagcggcg cgcgcgtttc gagcagcgct
     4921 gcgtagtggg ccggacgcag gcccaggccg aagccgggcg agggggcggt gagtgttgtc
     4981 atcggcggtg cgcggcccgg tgcgaagagg tctggacaga agccccgggc cgcgtgtcgg
     5041 cgcgaagctt acttggccga caggtcgccg atggtgccgc cttgttccag gcactgcttg
     5101 gccgaggtgg ccttgaagcc gtgacccttg caggcgttct ggcccttgca gctgtgttcg
     5161 gtggtggcgc agtcgctgtt gcccttgcag gcgtgcaggc cgtagcaatg caccttgtcg
     5221 ccggcgccca ctgcggcgcc cttgctgccg gccggcatgt cggcagcgaa aacggttccg
     5281 gacagggcga gcagggcagc agcagcggcg atcgaagcgc cgaaagtgtt cgtggacatc
     5341 gaaattctcc tcgggaggtg cggccgggcg ggatgcacgg caacgcggcg ggtgcgccgc
     5401 cggtgtccgg atcaccggcg gcgacagtcc tgcccacaag acctgcccga tgcggaaaac
     5461 cttaccggga tctttcgcgt gccctcaaat tttccggccg gccctgctcc gggccgtgat
     5521 gagcaggggc agggcggcgg gccgggtcac ttcgatccgg gtgtcgacgc gtccggcccg
     5581 tcgggcacca cccacggcag ctgctgcttc tgagcctcgt cgtgccagcg ctcttcctct
     5641 tcgtggatgt agcgctgggt ggtgcgcgcg tcggtgtggc gcgcgtcctt ctgcacgtag
     5701 cgctcgctca tgccggcgtc gagcttggcg gtgatgccgg tgtggcggcc ccagtgggcg
     5761 gaggcggcgc gcagcttgtc cttcttgtat tccgattctt ccggcagcag ttcggccgcg
     5821 gcgtagaaga tctttttcag gatctggttc agccggcgcg aggtgatcgg gctgcggtcc
     5881 ttcagcgaca ccagcagcgg cgtgaggtcg gtgcgcttcg gcatggccgg caggcccaga
     5941 tgcttgcggt agcgcaccag cgcatgaacc atgtcgtcgg ccaccggcac cttggcctgc
     6001 ttgccgccct tgccgaccac atgccaccac cagcgcccgc gctcttcgcg gaagctgttc
     6061 atgcggtgcg attccagctc gccggcgcgc ggcgccagca tgtagagcag ggcggcgatg
     6121 aagcgggcgc gctcgtactc gtcgcgctcg ccgtcggtgt cgcgcggcat ggcctcgatg
     6181 gcgcgggtga ccgcctgcca catttcggcg tcgagaaagc gctcgatctt ctgcatctct
     6241 tcggtctgcg cgatcacgtg cgccgggccc gcgttctgcg cggccagctt gcggcggcgc
     6301 tggcggatca ggccgagcgg gttgcccgcc agatagccgg cgtcgaccag ataggccatc
     6361 agcgaattga tggcggcgat cgcggtgagc accgccgatt ccgacagcgg gccgacgaag
     6421 ggccgccact cggcgcgcac ccgctgcacc ttggggccac accacagctt cgccggctgc
     6481 gggtcgacca ggaagttgag atagccctcg aagtcctgcc ggttcaggct ggacagcggc
     6541 ttgccgcact cgaccagcga ccacagcagc agccgttcgc actcgcgctg gtagatgcgg
     6601 tgggtgccgg gcgagcggtc gtattcggtc aggaagcagc ggatggcgtc catgtcggtg
     6661 tcggcgccga tctgcagccg cgcgcggtca gcgcggttca cgccgtcatg gccgtcgagt
     6721 gcgaccggca ccgaaatttc gtccatcgga cggatgggca ccggtgcgcc gccaggaaat
     6781 tcatcgctca tggggcgtga tgttaccgcc cgctccgctc gtgcggcaga gcggtgccgg
     6841 gaacctgccg ccgcaccggc ggtcaggtcg gaaatccgaa atggcggccg gccgggcgcg
     6901 cacgcgaaaa caggtatcct tcgccgctcc cgcgcacgac cgcccccgca tcgtctgcat
     6961 gaatcttctc gccaccgtcg tactgctccc gctgctggcc ggaacgtccg cctgtgccct
     7021 gatcgggcgc ggcaatacgc cggcgcgccg cctgctcacc gcgctggcgg ccggcggcgt
     7081 gacgctggcc gcactcgcgc tgctgctgcg catggcgccg gcggtattcg cgggcgaggt
     7141 gccggcagcc ggtttcgaat ggctgccgca gctgggcctg aacatcggct ggcggctcga
     7201 cggcctggcg ctgatgttcg gcctgctcat caccggcatc ggcgcgctca tcgtgctgta
     7261 cgcccatcac tatctgggca gcgaagaccc ggcgggcaag ttctacgcgc tgctcatgct
     7321 gttcatggcc gccatgctgg gcgtggtgct gtcggacaac ctgctcatgc tggtggtgtt
     7381 ctgggagctc accagcgtgt cctccttcct cctggtcggc tactggggtc accgggctga
     7441 cgcgcgcgcc ggcgcgcgga tggcgctggc ggtgaccggc ggcggcgggc tggtcatgct
     7501 ggctggcttc gtgctgctgg gccagatcgc cggcagctat gaactgaccg aaatcctgca
     7561 gcaccgcgaa cgcatcgtcg ccgacccgct ttacccgctg gtgctggcgc tggtgctgac
     7621 tggctgcttc accaagagcg cgcagctgcc cttccatttc tggctgccgg aggcgatggc
     7681 cgcgccgacg ccggtgtccg cctacctgca ctcggccacc atggtgaagg ccggcatttt
     7741 cctgatgctg cggctgtatc cggtgctggg cggcaccgcg ctgttcgaac aggtggtgac
     7801 cggcttcggt ctggccaccg tcaccttcgc cgcctgggtt gccatcttcc gtcacgacct
     7861 gaaggggctg ctcgcctatt cgaccgtgag ccacctcggt ttcatcaccg tcctcatcgg
     7921 cctcgatgcg ccgatggcca aggtggccgc ggtgtttcac atcctgaacc acgccacctt
     7981 caaggcggcg ctgttcatga gcgcgggcat cgtcgatcac gcctgtcaca gccgggacct
     8041 gcgccggctc ggcggcctgt acggctggat gccctggacc gccactttcg cgctgaccgc
     8101 ggccgcggcc atgggcggcc tgccgccgct gaacggcttc ctgtccaagg aaatgtattt
     8161 cgccgaagca ctggccggcg ccgaccgcct gagctggatc gtgccggcgg tcgcgctgct
     8221 ggcggcggtg tcgtccatgg cctattcgct gcgtttcgcg cacgacacct tcttcaacgg
     8281 cccgacgcgc gatctgccgg cggacgccca tccgcacgac ccgccggccg gcatgctggc
     8341 gccggtcgcg ctgctggcgc tgctgtgcgt ggcggtcggc ctgttcccgg aaagcactta
     8401 cgggccgctg gtgcggctgg cggccgatgc cgcgctgggc ggcccgccgc cggaattcca
     8461 tctggcactg tggcatggcg tgaatgggcc gctggcgatg agcgcggtgg cggtgctggc
     8521 cggcttcgcg ctgtatgccg gactgatgaa gggccgcgca ttgcacggtt acctgccgcg
     8581 cgcatggtcc ggcaagttgg cgttcggctg cgcgatcgac cggctgttcg cattcgccgg
     8641 ccgcgtcacc gccgccaccg agaacggttc gctgcagcgt tcgctgctca tcatggtggc
     8701 gttcgcggtg ctgctggccg cggcgccgtt ctggcaggcg gacgcgctgc cggcggcagg
     8761 agatcgcacg ctgatgccgg ccacgccgct ggcgctggcg ctgtgggcgc tgctgctcat
     8821 caccgccacc gtgatcgcgg ccacccatca tcagcgcttc cgcgcgctgg tgctggtggg
     8881 catcgtcggc ctcatcaccg cgctgacctt cgtcggcctg tcggcgccgg atctggcgct
     8941 cacccagctg tcggtcgagg tggtgtccac cgtgctcatg ctgatggggc tggcactgct
     9001 gccgcagcac acgccgcgtg aatcgagcgc gctgcggcgc ggccgcgacg cgctgctggc
     9061 gctggtggcc ggcggcggcg tggccgggct gacctggctc atgctgaccc gcaatcacga
     9121 ctcgatctcg tggttcttcc tggagcgctc gctgaccgaa ggcggcggca acaatgtggt
     9181 gaatgtgatc ctggtcgact tccgcggcta tgacaccttc ggcgaaatca cggtgctggg
     9241 catcgccgga ctgggcgcgc tggcgctgct cgacggcttc cgcacgcgcc ggccggccgc
     9301 cgacgccgac ggccgtgcct gggccttcga acagcagccg ctgctgctgc gggtggcggc
     9361 gcgcgtggtg ctgccgctgg cgctgctcgc ctccgcctac atctactggc gcggccacaa
     9421 catgccgggc ggcggcttca tcgccggcct gatgacttcg gtcgcgctgg tgatgcagta
     9481 catggcgctc ggtcaggcgc gtgccgaaag cctgctgcac ggcgcggccg gccgccgctt
     9541 cacccgctgg atcggtaccg gtctgggcat tgccgggctg accggcatcg gcgccttctg
     9601 gttcggccgc cccttcctga ccagcgcaca tggccacccg gcgctgccag tgatcggcga
     9661 actgccgctg gccagcgcgg cggccttcga tctgggtgtg tacatcacgg tggtcggcgc
     9721 cacgctgctc acactgtcgg tgctgggcgc ggccagcaag gaagatcacg catga
//
